Our site may be slower due to heavy traffic from automated "bots" and AI crawlers. We're working to fix this.

Dianne Mckay

Title(s)Clinical Professor (Voluntary), Family Medicine
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
vCardDownload vCard

    Collapse Research 
    Collapse research activities and funding
    Role of NOD2 in ischemia reperfusion injury
    NIH/NIDDK R01DK113162Apr 1, 2017 - Mar 31, 2021
    Role: Principal Investigator
    Role of Nlrp3 in Ischemic Organ Injury
    NIH/NIDDK R01DK091136Sep 15, 2011 - Aug 31, 2016
    Role: Principal Investigator
    The Role of Inflammation in Ischemic Organ Injury
    NIH/NIDDK R01DK075718Feb 1, 2008 - Jan 31, 2014
    Role: Principal Investigator
    Donor Antigen-Induced Peripheral Tolerance
    NIH/NIDDK R01DK062135Sep 1, 2002 - Mar 31, 2008
    Role: Principal Investigator
    MECHANISMS OF IN VIVO T CELL UNRESPONSIVENESS
    NIH/NIDDK R03DK058814Sep 30, 2000 - Aug 31, 2003
    Role: Principal Investigator
    TOLERANCE MECHANISMS--KIDNEY AND HEART TRANSPLANTATION
    NIH/NIDDK K08DK002472Aug 30, 1997 - Jun 30, 2003
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Simultaneous NOD1 and NOD2 Deletion in Hematopoietic Stem and Progenitor cells Promotes Long-Term Donor Chimerism. Transplant Cell Ther. 2026 Feb 02. Hawkes AA, Kasimsetty SG, Li H, Morris GP, Kurian SM, Almeida S, DeWolf SE, McKay DB. PMID: 41638572.
      View in: PubMed   Mentions:    Fields:    
    2. Pregnancy, Where Assisted Reproductive Technology and Transplant Science Intersect. Transplantation. 2025 Dec 01; 109(12):1825-1826. El Kassis Y, Josephson MA, McKay DB. PMID: 40958147.
      View in: PubMed   Mentions:    Fields:    
    3. Human pulmonary microvascular endothelial cells respond to DAMPs from injured renal tubular cells. Pulm Circ. 2024 Jul; 14(3):e12379. DeWolf SE, Hawkes AA, Kurian SM, Gorial DE, Hepokoski ML, Almeida SS, Posner IR, McKay DB. PMID: 38962184; PMCID: PMC11220341.
      View in: PubMed   Mentions: 3  
    4. CD100 boosts the inflammatory response in the challenge phase of allergic contact dermatitis in mice. Contact Dermatitis. 2023 Dec; 89(6):442-452. Mraz V, Funch AB, Jee MH, Gadsbøll AØ, Weber JF, Yeung K, Lohmann RKD, Hawkes A, Ødum N, Woetmann A, McKay D, Witherden D, Geisler C, Bonefeld CM. PMID: 37700557.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    5. The junctional adhesion molecule-like protein (JAML) is important for the inflammatory response during contact hypersensitivity. Contact Dermatitis. 2023 Nov; 89(5):323-334. Mraz V, Lohmann RKD, Menzel M, Hawkes A, Vaher H, Funch AB, Jee MH, Gadsbøll AØ, Weber JF, Yeung K, Ødum N, Woetmann A, McKay D, Witherden D, Geisler C, Bonefeld CM. PMID: 37619972; PMCID: PMC11034946.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    6. CD14 blockade to prevent ischemic injury to donor organs. Transpl Immunol. 2022 06; 72:101580. Own J, Ulevitch R, McKay D. PMID: 35283329; PMCID: PMC9762458.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    7. DAMPs Released From Injured Renal Tubular Epithelial Cells Activate Innate Immune Signals in Healthy Renal Tubular Epithelial Cells. Transplantation. 2022 08 01; 106(8):1589-1599. DeWolf SE, Kasimsetty SG, Hawkes AA, Stocks LM, Kurian SM, McKay DB. PMID: 34954736; PMCID: PMC9218002.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    8. Tests for the noninvasive diagnosis of kidney transplant rejection should be evaluated by kidney transplant programs. Am J Transplant. 2021 11; 21(11):3811. Danovitch GM, Bunnapradist S, Cohen D, Hariharan S, McKay D, Ratner L, Stegall MD, Steiner RW, Stock PG, Vincenti F. PMID: 34080294.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    9. Blockade of T cell activation induced by the simultaneous absence of Nod1 and Nod2 is bypassed by TLR2 signals. Transpl Immunol. 2021 04; 65:101348. Kasimsetty S, Hawkes A, DeWolf SE, Welch A, McKay DB. PMID: 33706865; PMCID: PMC10425202.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    10. TLR2 and NODs1 and 2 cooperate in inflammatory responses associated with renal ischemia reperfusion injury. Transpl Immunol. 2020 02; 58:101260. Kasimsetty SG, Hawkes A, Barekatain K, Soo E, Welch AK, McKay DB. PMID: 31760144; PMCID: PMC7041897.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    11. Optimizing organs for transplantation; advancements in perfusion and preservation methods. Transplant Rev (Orlando). 2020 01; 34(1):100514. Soo E, Marsh C, Steiner R, Stocks L, McKay DB. PMID: 31645271; PMCID: PMC6905200.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    12. Pro-Inflammatory Milieu in Human Kidney Perfusates Treated with Hypothermic Pulsatile Machine Perfusion. J Oncol Res Ther. 2019; 4(1). Ratigan E, Kasimsetty S, Cohen J, Shigeoka A, Stocks L, Mekeel K, Steiner R, McKay DB. PMID: 39554799; PMCID: PMC11566414.
      View in: PubMed   Mentions:
    13. Overcoming Translational Barriers in Acute Kidney Injury: A Report from an NIDDK Workshop. Clin J Am Soc Nephrol. 2018 07 06; 13(7):1113-1123. Zuk A, Palevsky PM, Fried L, Harrell FE, Khan S, McKay DB, Devey L, Chawla L, de Caestecker M, Kaufman JS, Thompson BT, Agarwal A, Greene T, Okusa MD, Bonventre JV, Dember LM, Liu KD, Humphreys BD, Gossett D, Xie Y, Norton JM, Kimmel PL, Star RA. PMID: 29523680; PMCID: PMC6032575.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimals
    14. Lack of Both Nucleotide-Binding Oligomerization Domain-Containing Proteins 1 and 2 Primes T Cells for Activation-Induced Cell Death. J Immunol. 2017 08 01; 199(3):1196-1205. Kasimsetty SG, Shigeoka AA, Scheinok AA, Gavin AL, Ulevitch RJ, McKay DB. PMID: 28652394; PMCID: PMC5600491.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    15. Expression of TLR2, NOD1, and NOD2 and the NLRP3 Inflammasome in Renal Tubular Epithelial Cells of Male versus Female Mice. Nephron. 2017; 137(1):68-76. DeWolf SE, Shigeoka AA, Scheinok A, Kasimsetty SG, Welch AK, McKay DB. PMID: 28614830; PMCID: PMC5599100.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    16. mTOR Inhibition by Everolimus Does Not Impair Closure of Punch Biopsy Wounds in Renal Transplant Patients. Transplant Direct. 2017 Apr; 3(4):e147. Dutt SB, Gonzales J, Boyett M, Costanzo A, Han PP, Steinberg S, McKay DB, Jameson JM. PMID: 28405603; PMCID: PMC5381740.
      View in: PubMed   Mentions: 2  
    17. Sex differences in transplantation. Transplant Rev (Orlando). 2017 07; 31(3):145-150. Momper JD, Misel ML, McKay DB. PMID: 28262425; PMCID: PMC5795092.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    18. The Bacterial Peptidoglycan-Sensing Molecules NOD1 and NOD2 Promote CD8+ Thymocyte Selection. J Immunol. 2017 04 01; 198(7):2649-2660. Martinic MM, Caminschi I, O'Keeffe M, Thinnes TC, Grumont R, Gerondakis S, McKay DB, Nemazee D, Gavin AL. PMID: 28202617; PMCID: PMC5360474.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    19. Pregnancy in chronic kidney disease and kidney transplantation. Kidney Int. 2017 05; 91(5):1047-1056. Webster P, Lightstone L, McKay DB, Josephson MA. PMID: 28209334.
      View in: PubMed   Mentions: 53     Fields:    Translation:Humans
    20. Urine Fibrosis Markers and Risk of Allograft Failure in Kidney Transplant Recipients: A Case-Cohort Ancillary Study of the FAVORIT Trial. Am J Kidney Dis. 2017 Mar; 69(3):410-419. Ix JH, Katz R, Bansal N, Foster M, Weiner DE, Tracy R, Jotwani V, Hughes-Austin J, McKay D, Gabbai F, Hsu CY, Bostom A, Levey AS, Shlipak MG. PMID: 28024930; PMCID: PMC7321838.
      View in: PubMed   Mentions: 34     Fields:    Translation:Humans
    21. Hematopoietic stem cells and solid organ transplantation. Transplant Rev (Orlando). 2016 10; 30(4):227-34. Elahimehr R, Scheinok AT, McKay DB. PMID: 27553809; PMCID: PMC5056784.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    22. Ischemia as a factor affecting innate immune responses in kidney transplantation. Curr Opin Nephrol Hypertens. 2016 Jan; 25(1):3-11. Kasimsetty SG, McKay DB. PMID: 26625866; PMCID: PMC4744806.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    23. Inflammation in AKI: Current Understanding, Key Questions, and Knowledge Gaps. J Am Soc Nephrol. 2016 Feb; 27(2):371-9. Rabb H, Griffin MD, McKay DB, Swaminathan S, Pickkers P, Rosner MH, Kellum JA, Ronco C, Acute Dialysis Quality Initiative Consensus XIII Work Group. PMID: 26561643; PMCID: PMC4731128.
      View in: PubMed   Mentions: 321     Fields:    Translation:HumansAnimals
    24. Exploring principles of hibernation for organ preservation. Transplant Rev (Orlando). 2016 Jan; 30(1):13-9. Ratigan ED, McKay DB. PMID: 26613668.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimals
    25. Simultaneous deletion of NOD1 and NOD2 inhibits in vitro alloresponses but does not prevent allograft rejection. Immunobiology. 2015 Nov; 220(11):1227-31. Kasimsetty SG, Scheinok AT, Shigeoka AA, McKay DB. PMID: 26159289; PMCID: PMC4558238.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    26. Assessment and management of hypertension in transplant patients. J Am Soc Nephrol. 2015 Jun; 26(6):1248-60. Weir MR, Burgess ED, Cooper JE, Fenves AZ, Goldsmith D, McKay D, Mehrotra A, Mitsnefes MM, Sica DA, Taler SJ. PMID: 25653099; PMCID: PMC4446882.
      View in: PubMed   Mentions: 58     Fields:    Translation:Humans
    27. Regulation of TLR2 and NLRP3 in primary murine renal tubular epithelial cells. Nephron Clin Pract. 2014; 127(1-4):119-23. Kasimsetty SG, DeWolf SE, Shigeoka AA, McKay DB. PMID: 25343834; PMCID: PMC4896108.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    28. Innate immunity in donor procurement. Curr Opin Organ Transplant. 2013 Apr; 18(2):154-60. Cheung KP, Kasimsetty SG, McKay DB. PMID: 23313940; PMCID: PMC4515366.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    29. Kidney transplantation and the ageing immune system. Nat Rev Nephrol. 2012 Dec; 8(12):700-8. McKay D, Jameson J. PMID: 23147756.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    30. Hypopigmentation and maternal-zygotic embryonic lethality caused by a hypomorphic mbtps1 mutation in mice. G3 (Bethesda). 2012 Apr; 2(4):499-504. Rutschmann S, Crozat K, Li X, Du X, Hanselman JC, Shigeoka AA, Brandl K, Popkin DL, McKay DB, Xia Y, Moresco EM, Beutler B. PMID: 22540041; PMCID: PMC3337478.
      View in: PubMed   Mentions: 6     Fields:    
    31. The role of innate immunity in donor organ procurement. Semin Immunopathol. 2011 Mar; 33(2):169-84. McKay DB. PMID: 21424913.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    32. Intracellular pattern recognition receptors and renal ischemia. Crit Rev Immunol. 2011; 31(4):297-306. McKay DB. PMID: 21899512.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    33. An inflammasome-independent role for epithelial-expressed Nlrp3 in renal ischemia-reperfusion injury. J Immunol. 2010 Nov 15; 185(10):6277-85. Shigeoka AA, Mueller JL, Kambo A, Mathison JC, King AJ, Hall WF, Correia Jda S, Ulevitch RJ, Hoffman HM, McKay DB. PMID: 20962258; PMCID: PMC3020135.
      View in: PubMed   Mentions: 127     Fields:    Translation:HumansAnimalsCells
    34. Pregnancy in the renal transplant recipient. Obstet Gynecol Clin North Am. 2010 Jun; 37(2):211-22. Josephson MA, McKay DB. PMID: 20685549.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    35. Nod1 and nod2 are expressed in human and murine renal tubular epithelial cells and participate in renal ischemia reperfusion injury. J Immunol. 2010 Mar 01; 184(5):2297-304. Shigeoka AA, Kambo A, Mathison JC, King AJ, Hall WF, da Silva Correia J, Ulevitch RJ, McKay DB. PMID: 20124104; PMCID: PMC3020136.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansAnimalsCells
    36. Defects in skin gamma delta T cell function contribute to delayed wound repair in rapamycin-treated mice. J Immunol. 2008 Sep 15; 181(6):3974-83. Mills RE, Taylor KR, Podshivalova K, McKay DB, Jameson JM. PMID: 18768852; PMCID: PMC2547144.
      View in: PubMed   Mentions: 43     Fields:    Translation:AnimalsCells
    37. Patients seeking alternatives to the long waiting list: a reality faced by transplant physicians. Prog Transplant. 2008 Sep; 18(3):203-7. McKay D, Potter SR, Behrend T, Stella F, Steinberg S. PMID: 18831487.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    38. Pregnancy after kidney transplantation. Clin J Am Soc Nephrol. 2008 Mar; 3 Suppl 2:S117-25. McKay DB, Josephson MA. PMID: 18308999; PMCID: PMC3152271.
      View in: PubMed   Mentions: 30     Fields:    Translation:Humans
    39. TLR2 is constitutively expressed within the kidney and participates in ischemic renal injury through both MyD88-dependent and -independent pathways. J Immunol. 2007 May 15; 178(10):6252-8. Shigeoka AA, Holscher TD, King AJ, Hall FW, Kiosses WB, Tobias PS, Mackman N, McKay DB. PMID: 17475853.
      View in: PubMed   Mentions: 130     Fields:    Translation:HumansAnimalsCells
    40. Considerations in the medical management of pregnancy in transplant recipients. Adv Chronic Kidney Dis. 2007 Apr; 14(2):156-67. Josephson MA, McKay DB. PMID: 17395118.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    41. Simultaneous deletion of MyD88 and Trif delays major histocompatibility and minor antigen mismatch allograft rejection. Eur J Immunol. 2006 Aug; 36(8):1994-2002. McKay D, Shigeoka A, Rubinstein M, Surh C, Sprent J. PMID: 16874736.
      View in: PubMed   Mentions: 31     Fields:    Translation:AnimalsCells
    42. Reproduction and pregnancy in transplant recipients: current practices. Prog Transplant. 2006 Jun; 16(2):127-32. McKay DB, Adams PL, Bumgardner GL, Davis CL, Fine RN, Krams SM, Martinez OM, Murphy B, Pavlakis M, Tolkoff-Rubin N, Sherman MS, Josephson MA. PMID: 16789701.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    43. Pregnancy in recipients of solid organs--effects on mother and child. N Engl J Med. 2006 Mar 23; 354(12):1281-93. McKay DB, Josephson MA. PMID: 16554530.
      View in: PubMed   Mentions: 60     Fields:    Translation:Humans
    44. Signaling T-cell survival and death by IL-2 and IL-15. Am J Transplant. 2005 Nov; 5(11):2623-31. Zambricki E, Shigeoka A, Kishimoto H, Sprent J, Burakoff S, Carpenter C, Milford E, McKay D. PMID: 16212621.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    45. Reproduction and transplantation: report on the AST Consensus Conference on Reproductive Issues and Transplantation. Am J Transplant. 2005 Jul; 5(7):1592-9. McKay DB, Josephson MA, Armenti VT, August P, Coscia LA, Davis CL, Davison JM, Easterling T, Friedman JE, Hou S, Karlix J, Lake KD, Lindheimer M, Matas AJ, Moritz MJ, Riely CA, Ross LF, Scott JR, Wagoner LE, Wrenshall L, Adams PL, Bumgardner GL, Fine RN, Goral S, Krams SM, Martinez OM, Tolkoff-Rubin N, Pavlakis M, Scantlebury V, Women's Health Committee of the American Society of Transplantation. PMID: 15943616.
      View in: PubMed   Mentions: 87     Fields:    Translation:Humans
    46. Renal insufficiency and end-stage renal disease in the heart transplant population. J Heart Lung Transplant. 2004 Mar; 23(3):289-300. Rubel JR, Milford EL, McKay DB, Jarcho JA. PMID: 15019638.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    47. Effect of anti-IL-2Ralpha antibody on IL-2-induced Jak/STAT signaling. Am J Transplant. 2002 Jan; 2(1):31-40. Tkaczuk J, Yu CL, Baksh S, Milford EL, Carpenter CB, Burakoff SJ, McKay DB. PMID: 12095053.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    48. Avoidance of cyclosporine in renal transplantation: effects of daclizumab, mycophenolate mofetil, and steroids. J Am Soc Nephrol. 2000 Oct; 11(10):1903-1909. Tran HTB, Acharya MK, McKay DB, Sayegh MH, Carpenter CB, Auchincloss H, Kirkman RL, Milford EL. PMID: 11004222.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCTClinical Trials
    Dianne's Networks
    Concepts (222)
    Derived automatically from this person's publications.
    Explore
    _
    Co-Authors (18)
    People in Profiles who have published with this person.
    Explore
    _
    Similar People (60)
    People who share similar concepts with this person.
    Explore
    _
    Same Department
    Search Department
    _

    UCSD Profiles is managed by the UC San Diego Altman Clinical and Translational Research Institute (ACTRI).
    This site is running Profiles RNS version UCSF-v3.1.0-21-g9d46e6c4 on PROFILES-PWEB03. We use cookies to operate our website. We also use cookies to analyze our site’s performance and improve your experience on our site. For more information about how we use cookies, please see our Website Terms of Use.

    Copyright © The Regents of the University of California