Chair, Division of Pharmaceutical Chemistry
Affiliate Faculty Department of Chemistry and Biochemistry
Our group synthesizes molecules with an emphasis on structurally complex compounds with profound biological effects. Natural products provide an ideal medium, providing challenging molecular architectures to enable the training of synthetic chemists as well as drive drug development. Through broad collaborative efforts with research groups in different disease areas we optimize compounds that originate in their laboratories for pharmacokinetic and pharmacodynamics properties. We also build novel molecular probes to decipher the mechanisms of action of these compounds.