Michael Kelner

Title(s)Professor, Pathology
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Collapse Research 
    Collapse Research Activities and Funding
    Halogenated Alkenes and Microsomal GSH-transferases
    NIH R01ES013687Aug 8, 2006 - Apr 30, 2012
    Role: Principal Investigator
    ALTERATION OF ERCC GENE EXPRESSION IN VITRO AND IN VIVO
    NIH R01AG013153Aug 1, 1996 - Jul 31, 2000
    Role: Principal Investigator
    Coordinated Regulation of Antioxidant Enzymes
    NIH R01CA052310Apr 1, 1992 - Jun 30, 2006
    Role: Principal Investigator
    GENETIC INSIGHT INTO OXIDATIVE DAMAGE
    NIH R01AG010746Jan 15, 1992 - Dec 31, 1995
    Role: Principal Investigator
    GPX1 ENZYME REGULATION BY OXIDATIVE XENOBIOTICS
    NIH R01ES004989Jul 1, 1990 - Nov 30, 2004
    Role: Principal Investigator
    INHIBITION OF PARAQUAT OXYGEN-MEDIATED TOXICITY
    NIH K08ES000142Jul 1, 1985 - Jan 31, 1989
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    1. Real-World Clinical Performance Evaluation of a Fourth-Generation HIV Antigen/Antibody Differentiation Test. J Appl Lab Med. 2021 11 01; 6(6):1417-1432. Krasowski MD, Wier D, Smith S, Riedel A, Lauseker-Hao Y, Kelner M, Wang S. PMID: 34333654.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCellsPHPublic Health
    2. SARS-CoV-2 Serology Status Detected by Commercialized Platforms Distinguishes Previous Infection and Vaccination Adaptive Immune Responses. J Appl Lab Med. 2021 09 01; 6(5):1109-1122. Suhandynata RT, Bevins NJ, Tran JT, Huang D, Hoffman MA, Lund K, Kelner MJ, McLawhon RW, Gonias SL, Nemazee D, Fitzgerald RL. PMID: 34170314; PMCID: PMC8409063.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCellsPHPublic Health
    3. SARS-CoV-2 Serology Status Detected by Commercialized Platforms Distinguishes Previous Infection and Vaccination Adaptive Immune Responses. medRxiv. 2021 Mar 12. Suhandynata RT, Bevins NJ, Tran JT, Huang D, Hoffman MA, Lund K, Kelner MJ, McLawhon RW, Gonias SL, Nemazee D, Fitzgerald RL. PMID: 33758902; PMCID: PMC7987061.
      View in: PubMed   Mentions:
    4. Commercial Serology Assays Predict Neutralization Activity against SARS-CoV-2. Clin Chem. 2021 01 30; 67(2):404-414. Suhandynata RT, Hoffman MA, Huang D, Tran JT, Kelner MJ, Reed SL, McLawhon RW, Voss JE, Nemazee D, Fitzgerald RL. PMID: 33084854; PMCID: PMC7665417.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansCells
    5. Multi-Platform Comparison of SARS-CoV-2 Serology Assays for the Detection of COVID-19. J Appl Lab Med. 2020 11 01; 5(6):1324-1336. Suhandynata RT, Hoffman MA, Kelner MJ, McLawhon RW, Reed SL, Fitzgerald RL. PMID: 32766840; PMCID: PMC7454554.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCellsPHPublic Health
    6. Longitudinal Monitoring of SARS-CoV-2 IgM and IgG Seropositivity to Detect COVID-19. J Appl Lab Med. 2020 09 01; 5(5):908-920. Suhandynata RT, Hoffman MA, Kelner MJ, McLawhon RW, Reed SL, Fitzgerald RL. PMID: 32428207; PMCID: PMC7313967.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansCellsPHPublic Health
    7. A Dilution Method to Mitigate Biotin Interference in Cardiac Troponin T Testing. J Appl Lab Med. 2019 11; 4(3):415-421. Bevins NJ, Hubbard JA, Fitzgerald RL, Kelner MJ. PMID: 31659079.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    8. MGST1, a GSH transferase/peroxidase essential for development and hematopoietic stem cell differentiation. Redox Biol. 2018 07; 17:171-179. Bräutigam L, Zhang J, Dreij K, Spahiu L, Holmgren A, Abe H, Tew KD, Townsend DM, Kelner MJ, Morgenstern R, Johansson K. PMID: 29702404; PMCID: PMC6006721.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    9. Hydroxyurea derivatives of irofulven with improved antitumor efficacy. Bioorg Med Chem Lett. 2016 Apr 01; 26(7):1836-8. Staake MD, Kashinatham A, McMorris TC, Estes LA, Kelner MJ. PMID: 26922141.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    10. Absence of MGST1 mRNA and protein expression in human neuroblastoma cell lines and primary tissue. Free Radic Biol Med. 2014 Apr; 69:167-71. Kelner MJ, Diccianni MB, Yu AL, Rutherford MR, Estes LA, Morgenstern R. PMID: 24486338; PMCID: PMC4010302.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    11. A rare and unique case of aggressive IgE-λ plasma cell myeloma in a 28-year-old woman presented initially as an orbital mass. Hum Pathol. 2012 Dec; 43(12):2376-84. Li K, Ku G, Yan M, Broome HE, Kelner M, Wang HY. PMID: 23084304.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    12. Structure-activity studies of urea, carbamate, and sulfonamide derivatives of acylfulvene. J Med Chem. 2010 Feb 11; 53(3):1109-16. McMorris TC, Chimmani R, Alisala K, Staake MD, Banda G, Kelner MJ. PMID: 20067264.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    13. Stability of levothyroxine sodium 0.4 microg/mL in 0.9% sodium chloride injection. Prog Transplant. 2009 Dec; 19(4):354-6; quiz 357. Stadalman KA, Kelner MJ, Box K, Dominguez A, Rigby JF. PMID: 20050459.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    14. Preparation of crotaline F-ab antivenom (CroFab) with automated mixing methods: in vitro observations. Clin Toxicol (Phila). 2009 Jan; 47(1):69-71. Vohra R, Kelner M, Clark RF. PMID: 19153853.
      View in: PubMed   Mentions:    Fields:    
    15. CroFab reconstitution in various media: an in vitro solubility study. Clin Toxicol (Phila). 2008 Nov; 46(9):808-10. Vohra R, Clark R, Kelner M. PMID: 18821147.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    16. Synergy of irofulven in combination with other DNA damaging agents: synergistic interaction with altretamine, alkylating, and platinum-derived agents in the MV522 lung tumor model. Cancer Chemother Pharmacol. 2008 Dec; 63(1):19-26. Kelner MJ, McMorris TC, Rojas RJ, Estes LA, Suthipinijtham P. PMID: 18305940.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    17. Synergy of Irofulven in combination with various anti-metabolites, enzyme inhibitors, and miscellaneous agents in MV522 lung carcinoma cells: marked interaction with gemcitabine and 5-fluorouracil. Invest New Drugs. 2008 Oct; 26(5):407-15. Kelner MJ, McMorris TC, Rojas RJ, Estes LA, Suthipinijtham P. PMID: 18227973.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    18. Disruption of the ugt1 locus in mice resembles human Crigler-Najjar type I disease. J Biol Chem. 2008 Mar 21; 283(12):7901-11. Nguyen N, Bonzo JA, Chen S, Chouinard S, Kelner MJ, Hardiman G, Bélanger A, Tukey RH. PMID: 18180294.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimals
    19. Synthesis and antitumor activity of amine analogs of irofulven. Bioorg Med Chem Lett. 2007 Dec 15; 17(24):6770-2. McMorris TC, Chimmani R, Gurram M, Staake MD, Kelner MJ. PMID: 17977722.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    20. Phase I/II study of continuous-infusion troxacitabine in refractory acute myeloid leukemia. J Clin Oncol. 2007 Jan 01; 25(1):10-5. Roboz GJ, Giles FJ, Ritchie EK, Allen-Bard S, Curcio TJ, Wilkes MA, Park SL, Kantarjian HM, Faderl S, Ravandi F, Kelner MJ, Feldman EJ. PMID: 17146106.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCTClinical Trials
    21. Structural organization of the murine microsomal glutathione S-transferase gene (MGST1) from the 129/SvJ strain: identification of the promoter region and a comprehensive examination of tissue expression. Biochim Biophys Acta. 2004 May 25; 1678(2-3):163-9. Kelner MJ, Bagnell RD, Morgenstern R. PMID: 15157743.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    22. Synthesis and biological activity of enantiomers of antitumor irofulven. J Org Chem. 2004 Feb 06; 69(3):619-23. McMorris TC, Staake MD, Kelner MJ. PMID: 14750783.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    23. Structure-activity relationship studies of illudins: analogues possessing a spiro-cyclobutane ring. J Org Chem. 2003 Dec 12; 68(25):9648-53. McMorris TC, Cong Q, Kelner MJ. PMID: 14656090.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    24. Basal expression of the human MAPEG members microsomal glutathione transferase 1 and prostaglandin E synthase genes is mediated by Sp1 and Sp3. Biochim Biophys Acta. 2003 Jun 19; 1627(2-3):79-84. Ekström L, Lyrenäs L, Jakobsson PJ, Morgenstern R, Kelner MJ. PMID: 12818425.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    25. Reaction of irofulven with zinc and acid. J Nat Prod. 2003 Feb; 66(2):310-2. McMorris TC, Moon SS, Kelner MJ. PMID: 12608875.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    26. Anti-tumour compounds illudin S and Irofulven induce DNA lesions ignored by global repair and exclusively processed by transcription- and replication-coupled repair pathways. DNA Repair (Amst). 2002 Dec 05; 1(12):1027-38. Jaspers NG, Raams A, Kelner MJ, Ng JM, Yamashita YM, Takeda S, McMorris TC, Hoeijmakers JH. PMID: 12531012.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansAnimalsCells
    27. Sesquiterpenes from Omphalotus illudens. Phytochemistry. 2002 Oct; 61(4):395-8. McMorris TC, Kashinatham A, Lira R, Rundgren H, Gantzel PK, Kelner MJ, Dawe R. PMID: 12377232.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    28. Enhanced antitumor activity of irofulven in combination with antimitotic agents. Invest New Drugs. 2002 Aug; 20(3):271-9. Kelner MJ, McMorris TC, Rojas RJ, Trani NA, Velasco TR, Estes LA, Suthipinijtham P. PMID: 12201490.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    29. Enhanced antitumor activity of irofulven in combination with thiotepa or mitomycin C. Cancer Chemother Pharmacol. 2002 May; 49(5):412-8. Kelner MJ, McMorris TC, Rojas RJ, Trani NA, Estes L. PMID: 11976836.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    30. Structure-activity studies of antitumor agent irofulven (hydroxymethylacylfulvene) and analogues. J Org Chem. 2001 Sep 07; 66(18):6158-63. McMorris TC, Yu J, Lira R, Dawe R, MacDonald JR, Waters SJ, Estes LA, Kelner MJ. PMID: 11529745.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    31. The effect of gamma hydroxybutyrate on serum osmolality. J Toxicol Clin Toxicol. 2001; 39(4):417-8. Ingels M, Kelner MJ, Clark RF. PMID: 11527239.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    32. Sesquiterpenes from the basidiomycete Omphalotus illudens. J Nat Prod. 2000 Nov; 63(11):1557-9. McMorris TC, Lira R, Gantzel PK, Kelner MJ, Dawe R. PMID: 11087609.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    33. Preparation and biological activity of amino acid and peptide conjugates of antitumor hydroxymethylacylfulvene. J Med Chem. 2000 Sep 21; 43(19):3577-80. McMorris TC, Yu J, Ngo HT, Wang H, Kelner MJ. PMID: 11000013.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    34. Structural organization of the human gastrointestinal glutathione peroxidase (GPX2) promoter and 3'-nontranscribed region: transcriptional response to exogenous redox agents. Gene. 2000 May 02; 248(1-2):109-16. Kelner MJ, Bagnell RD, Montoya MA, Lanham KA. PMID: 10806356.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    35. Structural organization of the microsomal glutathione S-transferase gene (MGST1) on chromosome 12p13.1-13.2. Identification of the correct promoter region and demonstration of transcriptional regulation in response to oxidative stress. J Biol Chem. 2000 Apr 28; 275(17):13000-6. Kelner MJ, Bagnell RD, Montoya MA, Estes LA, Forsberg L, Morgenstern R. PMID: 10777602.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    36. Structural organization of the human glutathione reductase gene: determination of correct cDNA sequence and identification of a mitochondrial leader sequence. Biochem Biophys Res Commun. 2000 Mar 16; 269(2):366-8. Kelner MJ, Montoya MA. PMID: 10708558.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    37. Efficacy of MGI 114 (HMAF) against the MRP+ metastatic MV522 lung carcinoma xenograft. Anticancer Drugs. 2000 Mar; 11(3):217-24. Kelner MJ, McMorris TC, Estes LA, Oval MY, Rojas RJ, Lynn JR, Lanham KA, Samson KM. PMID: 10831281.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    38. Anti-leukemic action of the novel agent MGI 114 (HMAF) and synergistic action with topotecan. Leukemia. 2000 Jan; 14(1):136-41. Kelner MJ, McMorris TC, Estes L, Samson KM, Trani NA, MacDonald JR. PMID: 10637489.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    39. Metabolism of antitumor hydroxymethylacylfulvene by rat liver cytosol. Drug Metab Dispos. 1999 Sep; 27(9):983-5. McMorris TC, Elayadi AN, Yu J, Hu Y, Kelner MJ. PMID: 10460795.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    40. Distribution of microsomal glutathione transferase 1 in mammalian tissues. A predominant alternate first exon in human tissues. Eur J Biochem. 1999 Mar; 260(2):409-13. Estonius M, Forsberg L, Danielsson O, Weinander R, Kelner MJ, Morgenstern R. PMID: 10095775.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    41. Metabolism of antitumor acylfulvene by rat liver cytosol. Biochem Pharmacol. 1999 Jan 01; 57(1):83-8. McMorris TC, Elayadi AN, Yu J, Kelner MJ. PMID: 9920288.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    42. Characterization of MGI 114 (HMAF) histiospecific toxicity in human tumor cell lines. Cancer Chemother Pharmacol. 1999; 44(3):235-40. Kelner MJ, McMorris TC, Montoya MA, Estes L, Uglik SF, Rutherford M, Samson KM, Bagnell RD, Taetle R. PMID: 10453725.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    43. Mice with a homozygous null mutation for the most abundant glutathione peroxidase, Gpx1, show increased susceptibility to the oxidative stress-inducing agents paraquat and hydrogen peroxide. J Biol Chem. 1998 Aug 28; 273(35):22528-36. de Haan JB, Bladier C, Griffiths P, Kelner M, O'Shea RD, Cheung NS, Bronson RT, Silvestro MJ, Wild S, Zheng SS, Beart PM, Hertzog PJ, Kola I. PMID: 9712879.
      View in: PubMed   Mentions: 103     Fields:    Translation:AnimalsCells
    44. Structural organization of the human selenium-dependent phospholipid hydroperoxide glutathione peroxidase gene (GPX4): chromosomal localization to 19p13.3. Biochem Biophys Res Commun. 1998 Aug 10; 249(1):53-5. Kelner MJ, Montoya MA. PMID: 9705830.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    45. Efficacy of MGI 114 (6-hydroxymethylacylfulvene, HMAF) against the mdr1/gp170 metastatic MV522 lung carcinoma xenograft. Eur J Cancer. 1998 May; 34(6):908-13. Kelner MJ, McMorris TC, Estes L, Samson KM, Bagnell RD, Taetle R. PMID: 9797706.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    46. Characterization of acylfulvene histiospecific toxicity in human tumor cell lines. Cancer Chemother Pharmacol. 1998; 41(3):237-42. Kelner MJ, McMorris TC, Montoya MA, Estes L, Uglik SF, Rutherford M, Samson KM, Bagnell RD, Taetle R. PMID: 9443641.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    47. Design and Synthesis of Antitumor Acylfulvenes. J Org Chem. 1997 May 02; 62(9):3015-3018. McMorris TC, Yu J, Hu Y, Estes LA, Kelner MJ. PMID: 11671671.
      View in: PubMed   Mentions: 2     Fields:    
    48. Preclinical antitumor activity of 6-hydroxymethylacylfulvene, a semisynthetic derivative of the mushroom toxin illudin S. Cancer Res. 1997 Jan 15; 57(2):279-83. MacDonald JR, Muscoplat CC, Dexter DL, Mangold GL, Chen SF, Kelner MJ, McMorris TC, Von Hoff DD. PMID: 9000568.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    49. Reactive oxygen species and their contribution to pathology in Down syndrome. Adv Pharmacol. 1997; 38:379-402. de Haan JB, Wolvetang EJ, Cristiano F, Iannello R, Bladier C, Kelner MJ, Kola I. PMID: 8895817.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    50. Characterization of cellular accumulation and toxicity of illudin S in sensitive and nonsensitive tumor cells. Cancer Chemother Pharmacol. 1997; 40(1):65-71. Kelner MJ, McMorris TC, Montoya MA, Estes L, Rutherford M, Samson KM, Taetle R. PMID: 9137532.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    51. Heterologous expression of carbonyl reductase: demonstration of prostaglandin 9-ketoreductase activity and paraquat resistance. Life Sci. 1997; 61(23):2317-22. Kelner MJ, Estes L, Rutherford M, Uglik SF, Peitzke JA. PMID: 9408054.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    52. (Hydroxymethyl)acylfulvene: an illudin derivative with superior antitumor properties. J Nat Prod. 1996 Sep; 59(9):896-9. McMorris TC, Kelner MJ, Wang W, Yu J, Estes LA, Taetle R. PMID: 8864242.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    53. Structural organization of the human microsomal glutathione S-transferase gene (GST12). Genomics. 1996 Aug 15; 36(1):100-3. Kelner MJ, Stokely MN, Stovall NE, Montoya MA. PMID: 8812420.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    54. Elevation in the ratio of Cu/Zn-superoxide dismutase to glutathione peroxidase activity induces features of cellular senescence and this effect is mediated by hydrogen peroxide. Hum Mol Genet. 1996 Feb; 5(2):283-92. de Haan JB, Cristiano F, Iannello R, Bladier C, Kelner MJ, Kola I. PMID: 8824885.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansCells
    55. Acylfulvenes, a new class of potent antitumor agents. Experientia. 1996 Jan 16; 52(1):75-80. McMorris TC, Kelner MJ, Wang W, Diaz MA, Estes LA, Taetle R. PMID: 8575564.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimals
    56. Efficacy of HMAF (MGI-114) in the MV522 metastatic lung carcinoma xenograft model nonresponsive to traditional anticancer agents. Invest New Drugs. 1996; 14(2):161-7. Kelner MJ, McMorris TC, Estes L, Wang W, Samson KM, Taetle R. PMID: 8913837.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    57. Efficacy of Acylfulvene Illudin analogues against a metastatic lung carcinoma MV522 xenograft nonresponsive to traditional anticancer agents: retention of activity against various mdr phenotypes and unusual cytotoxicity against ERCC2 and ERCC3 DNA helicase-deficient cells. Cancer Res. 1995 Nov 01; 55(21):4936-40. Kelner MJ, McMorris TC, Estes L, Starr RJ, Rutherford M, Montoya M, Samson KM, Taetle R. PMID: 7585533.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    58. Heterologous expression of selenium-dependent glutathione peroxidase affords cellular resistance to paraquat. Arch Biochem Biophys. 1995 Oct 20; 323(1):40-6. Kelner MJ, Bagnell RD, Uglik SF, Montoya MA, Mullenbach GT. PMID: 7487071.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    59. Superoxide dismutase abolishes the platelet-derived growth factor-induced release of prostaglandin E2 by blocking induction of nitric oxide synthase: role of superoxide. Arch Biochem Biophys. 1995 Sep 10; 322(1):31-8. Kelner MJ, Uglik SF. PMID: 7574691.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    60. In vitro and in vivo studies on the anticancer activity of dehydroilludin M. Anticancer Res. 1995 May-Jun; 15(3):873-8. Kelner MJ, McMorris TC, Taetle R. PMID: 7645974.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    61. Nonresponsiveness of the metastatic human lung carcinoma MV522 xenograft to conventional anticancer agents. Anticancer Res. 1995 May-Jun; 15(3):867-71. Kelner MJ, McMorris TC, Estes L, Starr R, Samson K, Varki N, Taetle R. PMID: 7645973.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    62. Transfection with human copper-zinc superoxide dismutase induces bidirectional alterations in other antioxidant enzymes, proteins, growth factor response, and paraquat resistance. Free Radic Biol Med. 1995 Mar; 18(3):497-506. Kelner MJ, Bagnell R, Montoya M, Estes L, Uglik SF, Cerutti P. PMID: 9101240.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    63. Characterization of illudin S sensitivity in DNA repair-deficient Chinese hamster cells. Unusually high sensitivity of ERCC2 and ERCC3 DNA helicase-deficient mutants in comparison to other chemotherapeutic agents. Biochem Pharmacol. 1994 Jul 19; 48(2):403-9. Kelner MJ, McMorris TC, Estes L, Rutherford M, Montoya M, Goldstein J, Samson K, Starr R, Taetle R. PMID: 8053936.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    64. Mechanism of prostaglandin E2 release and increase in PGH2/PGE2 isomerase activity by PDGF: involvement of nitric oxide. Arch Biochem Biophys. 1994 Jul; 312(1):240-3. Kelner MJ, Uglik SF. PMID: 7518221.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    65. PDGF-induces the glutathione-dependent enzyme PGH2/PGE2 isomerase in NIH3T3 and pEJ transformed fibroblasts. Biochem Biophys Res Commun. 1994 Jan 14; 198(1):298-303. Kelner MJ, Uglik SF. PMID: 8292033.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    66. Thioureas and thioamides react with superoxide to form a novel product. Free Radic Biol Med. 1993 Feb; 14(2):225-6. Kelner MJ. PMID: 8381108.
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    67. HPLC determination of a new anticancer agent (acylfulvene) in serum. Neoplasma. 1992; 39(6):369-73. Brandsteterová E, Kelner MJ, McMorris TC, Estes L, Bagnell R, Montoya M. PMID: 1491727.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    68. Alteration of growth rate and fibronectin by imbalances in superoxide dismutase and glutathione peroxidase activity. Adv Exp Med Biol. 1991; 283:305-9. Kelner MJ, Bagnell R. PMID: 2069002.
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    69. On the mechanism of toxicity of illudins: the role of glutathione. Chem Res Toxicol. 1990 Nov-Dec; 3(6):574-9. McMorris TC, Kelner MJ, Wang W, Moon S, Taetle R. PMID: 2103329.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    70. Preclinical evaluation of illudins as anticancer agents: basis for selective cytotoxicity. J Natl Cancer Inst. 1990 Oct 03; 82(19):1562-5. Kelner MJ, McMorris TC, Taetle R. PMID: 2402017.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    71. Alteration of endogenous glutathione peroxidase, manganese superoxide dismutase, and glutathione transferase activity in cells transfected with a copper-zinc superoxide dismutase expression vector. Explanation for variations in paraquat resistance. J Biol Chem. 1990 Jul 05; 265(19):10872-5. Kelner MJ, Bagnell R. PMID: 2358446.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    72. Thioureas react with superoxide radicals to yield a sulfhydryl compound. Explanation for protective effect against paraquat. J Biol Chem. 1990 Jan 25; 265(3):1306-11. Kelner MJ, Bagnell R, Welch KJ. PMID: 2153125.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    73. Glutathione-dependent enzymes alone can produce paraquat resistance. Free Radic Biol Med. 1990; 9(2):149-53. Kelner MJ, Bagnell R. PMID: 2172100.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    74. Paraquat resistance associated with reduced NADPH reductase in an energy-dependent paraquat-accumulating cell line. Arch Biochem Biophys. 1989 Nov 01; 274(2):366-74. Kelner MJ, Bagnell R. PMID: 2802616.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    75. Inactivation of intracellular copper-zinc superoxide dismutase by copper chelating agents without glutathione depletion and methemoglobin formation. Free Radic Biol Med. 1989; 6(4):355-60. Kelner MJ, Bagnell R, Hale B, Alexander NM. PMID: 2540068.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    76. Definitive liquid-chromatographic demonstration that N-ethylglycine is the metabolite of lidocaine that interferes in the Kodak sarcosine oxidase-coupled method for creatinine. Clin Chem. 1988 Dec; 34(12):2569-72. Roberts RT, Alexander NM, Kelner MJ. PMID: 3197304.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    77. Methylene blue competes with paraquat for reduction by flavo-enzymes resulting in decreased superoxide production in the presence of heme proteins. Arch Biochem Biophys. 1988 May 01; 262(2):422-6. Kelner MJ, Bagnell R, Hale B, Alexander NM. PMID: 2835006.
      View in: PubMed   Mentions: 17     Fields:    Translation:Cells
    78. Potential of methylene blue to block oxygen radical generation in reperfusion injury. Basic Life Sci. 1988; 49:895-8. Kelner MJ, Bagnell R, Hale B, Alexander NM. PMID: 2855011.
      View in: PubMed   Mentions: 17     Fields:    Translation:Animals
    79. Newer cardiac agents: antiarrhythmics and antianginal agents. Clin Lab Med. 1987 Sep; 7(3):567-85. Kelner MJ. PMID: 3308297.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    80. Preclinical evaluation of illudins as anticancer agents. Cancer Res. 1987 Jun 15; 47(12):3186-9. Kelner MJ, McMorris TC, Beck WT, Zamora JM, Taetle R. PMID: 3472654.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    81. Endocrine hormone abnormalities in Amanita poisoning. J Toxicol Clin Toxicol. 1987; 25(1-2):21-37. Kelner MJ, Alexander NM. PMID: 3586085.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    82. Thiol stimulation of the cytochrome P-450-dependent reduction of 1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane (DDT) to 1,1-dichloro-2,2-bis(p-chlorophenyl)ethane (DDD). Biochem Pharmacol. 1986 Jun 01; 35(11):1805-7. Kelner MJ, McLenithan JC, Anders MW. PMID: 3718529.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    83. Oxidation of glutathione by methylene blue is equivalent in G-6-PD deficient and normal erythrocytes. Res Commun Chem Pathol Pharmacol. 1986 May; 52(2):265-8. Kelner MJ, Alexander NM. PMID: 3715203.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    84. Inhibition of erythrocyte superoxide dismutase by diethyldithiocarbamate also results in oxyhemoglobin-catalyzed glutathione depletion and methemoglobin production. J Biol Chem. 1986 Feb 05; 261(4):1636-41. Kelner MJ, Alexander NM. PMID: 3003078.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    85. In vitro oxidation of uric acid in serum by methylene blue. Clin Chem. 1986 Jan; 32(1 Pt 1):177-9. Andranovich T, Kelner MJ. PMID: 3940703.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    86. Methylene blue directly oxidizes glutathione without the intermediate formation of hydrogen peroxide. J Biol Chem. 1985 Dec 05; 260(28):15168-71. Kelner MJ, Alexander NM. PMID: 4066667.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    87. Mismeasurement of methemoglobin ("methemoglobin revisited") Clin Chem. 1985 Jan; 31(1):168-9. Kelner MJ, Bailey DN. PMID: 3965210.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    88. Rapid separation and identification of myoglobin and hemoglobin in urine by centrifugation through a microconcentrator membrane. Clin Chem. 1985 Jan; 31(1):112-4. Kelner MJ, Alexander NM. PMID: 3965185.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    89. Positive diphenhydramine interference in the EMIT-d.a.u. assay. Clin Chem. 1984 Aug; 30(8):1430. Kelner MJ. PMID: 6378429.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    90. Micro-analysis for quinidine in serum by thin-layer chromatography followed by fluorescence densitometry. Clin Chem. 1983 Dec; 29(12):2100-2. Kelner M, Bailey DN. PMID: 6640909.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    91. Reversed-phase liquid-chromatographic simultaneous analysis for thiopental and pentobarbital in serum. Clin Chem. 1983 Jun; 29(6):1097-100. Kelner M, Bailey DN. PMID: 6851102.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
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