Michael Kelner

Title(s)Professor, Pathology
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Collapse Research 
    Collapse Research Activities and Funding
    Halogenated Alkenes and Microsomal GSH-transferases
    NIH R01ES013687Aug 8, 2006 - Apr 30, 2012
    Role: Principal Investigator
    ALTERATION OF ERCC GENE EXPRESSION IN VITRO AND IN VIVO
    NIH R01AG013153Aug 1, 1996 - Jul 31, 2000
    Role: Principal Investigator
    Coordinated Regulation of Antioxidant Enzymes
    NIH R01CA052310Apr 1, 1992 - Jun 30, 2006
    Role: Principal Investigator
    GENETIC INSIGHT INTO OXIDATIVE DAMAGE
    NIH R01AG010746Jan 15, 1992 - Dec 31, 1995
    Role: Principal Investigator
    GPX1 ENZYME REGULATION BY OXIDATIVE XENOBIOTICS
    NIH R01ES004989Jul 1, 1990 - Nov 30, 2004
    Role: Principal Investigator
    INHIBITION OF PARAQUAT OXYGEN-MEDIATED TOXICITY
    NIH K08ES000142Jul 1, 1985 - Jan 31, 1989
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Evaluation of a Benzodiazepine Immunoassay for Urine Drug Testing in Clinical Specimens. J Appl Lab Med. 2024 Aug 20. Ge M, Alabi A, Kelner MJ, Fitzgerald RL, Suhandynata RT. PMID: 39163145.
      View in: PubMed   Mentions:    Fields:    Translation:HumansPHPublic Health
    2. Evaluating the performance of the Roche FEN2 fentanyl immunoassay and its clinical implementation: The role of LDT-based mass spectrometry testing. J Mass Spectrom Adv Clin Lab. 2023 Apr; 28:105-113. Menlyadiev M, Suhandynata RT, Lund K, Kelner MJ, Fitzgerald RL. PMID: 37025609; PMCID: PMC10070886.
      View in: PubMed   Mentions: 2  
    3. Comparison of two highly sensitive benzodiazepine immunoassay lab developed tests for urine drug testing in clinical specimens. J Mass Spectrom Adv Clin Lab. 2023 Apr; 28:91-98. Lund K, Menlyadiev M, Lee K, Kelner MJ, Fitzgerald RL, Suhandynata RT. PMID: 36937812; PMCID: PMC10020650.
      View in: PubMed   Mentions: 1  
    4. Real-World Clinical Performance Evaluation of a Fourth-Generation HIV Antigen/Antibody Differentiation Test. J Appl Lab Med. 2021 11 01; 6(6):1417-1432. Krasowski MD, Wier D, Smith S, Riedel A, Lauseker-Hao Y, Kelner M, Wang S. PMID: 34333654.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCellsPHPublic Health
    5. SARS-CoV-2 Serology Status Detected by Commercialized Platforms Distinguishes Previous Infection and Vaccination Adaptive Immune Responses. J Appl Lab Med. 2021 09 01; 6(5):1109-1122. Suhandynata RT, Bevins NJ, Tran JT, Huang D, Hoffman MA, Lund K, Kelner MJ, McLawhon RW, Gonias SL, Nemazee D, Fitzgerald RL. PMID: 34170314; PMCID: PMC8409063.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCellsPHPublic Health
    6. SARS-CoV-2 Serology Status Detected by Commercialized Platforms Distinguishes Previous Infection and Vaccination Adaptive Immune Responses. medRxiv. 2021 Mar 12. Suhandynata RT, Bevins NJ, Tran JT, Huang D, Hoffman MA, Lund K, Kelner MJ, McLawhon RW, Gonias SL, Nemazee D, Fitzgerald RL. PMID: 33758902; PMCID: PMC7987061.
      View in: PubMed   Mentions:
    7. Commercial Serology Assays Predict Neutralization Activity against SARS-CoV-2. Clin Chem. 2021 01 30; 67(2):404-414. Suhandynata RT, Hoffman MA, Huang D, Tran JT, Kelner MJ, Reed SL, McLawhon RW, Voss JE, Nemazee D, Fitzgerald RL. PMID: 33084854; PMCID: PMC7665417.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCells
    8. Multi-Platform Comparison of SARS-CoV-2 Serology Assays for the Detection of COVID-19. J Appl Lab Med. 2020 11 01; 5(6):1324-1336. Suhandynata RT, Hoffman MA, Kelner MJ, McLawhon RW, Reed SL, Fitzgerald RL. PMID: 32766840; PMCID: PMC7454554.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCellsPHPublic Health
    9. Longitudinal Monitoring of SARS-CoV-2 IgM and IgG Seropositivity to Detect COVID-19. J Appl Lab Med. 2020 09 01; 5(5):908-920. Suhandynata RT, Hoffman MA, Kelner MJ, McLawhon RW, Reed SL, Fitzgerald RL. PMID: 32428207; PMCID: PMC7313967.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansCellsPHPublic Health
    10. A Dilution Method to Mitigate Biotin Interference in Cardiac Troponin T Testing. J Appl Lab Med. 2019 11; 4(3):415-421. Bevins NJ, Hubbard JA, Fitzgerald RL, Kelner MJ. PMID: 31659079.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    11. MGST1, a GSH transferase/peroxidase essential for development and hematopoietic stem cell differentiation. Redox Biol. 2018 07; 17:171-179. Bräutigam L, Zhang J, Dreij K, Spahiu L, Holmgren A, Abe H, Tew KD, Townsend DM, Kelner MJ, Morgenstern R, Johansson K. PMID: 29702404; PMCID: PMC6006721.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    12. Hydroxyurea derivatives of irofulven with improved antitumor efficacy. Bioorg Med Chem Lett. 2016 Apr 01; 26(7):1836-8. Staake MD, Kashinatham A, McMorris TC, Estes LA, Kelner MJ. PMID: 26922141.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    13. Absence of MGST1 mRNA and protein expression in human neuroblastoma cell lines and primary tissue. Free Radic Biol Med. 2014 Apr; 69:167-71. Kelner MJ, Diccianni MB, Yu AL, Rutherford MR, Estes LA, Morgenstern R. PMID: 24486338; PMCID: PMC4010302.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    14. A rare and unique case of aggressive IgE-λ plasma cell myeloma in a 28-year-old woman presented initially as an orbital mass. Hum Pathol. 2012 Dec; 43(12):2376-84. Li K, Ku G, Yan M, Broome HE, Kelner M, Wang HY. PMID: 23084304.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    15. Structure-activity studies of urea, carbamate, and sulfonamide derivatives of acylfulvene. J Med Chem. 2010 Feb 11; 53(3):1109-16. McMorris TC, Chimmani R, Alisala K, Staake MD, Banda G, Kelner MJ. PMID: 20067264.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    16. Stability of levothyroxine sodium 0.4 microg/mL in 0.9% sodium chloride injection. Prog Transplant. 2009 Dec; 19(4):354-6; quiz 357. Stadalman KA, Kelner MJ, Box K, Dominguez A, Rigby JF. PMID: 20050459.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    17. Preparation of crotaline F-ab antivenom (CroFab) with automated mixing methods: in vitro observations. Clin Toxicol (Phila). 2009 Jan; 47(1):69-71. Vohra R, Kelner M, Clark RF. PMID: 19153853.
      View in: PubMed   Mentions:    Fields:    
    18. CroFab reconstitution in various media: an in vitro solubility study. Clin Toxicol (Phila). 2008 Nov; 46(9):808-10. Vohra R, Clark R, Kelner M. PMID: 18821147.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    19. Synergy of irofulven in combination with other DNA damaging agents: synergistic interaction with altretamine, alkylating, and platinum-derived agents in the MV522 lung tumor model. Cancer Chemother Pharmacol. 2008 Dec; 63(1):19-26. Kelner MJ, McMorris TC, Rojas RJ, Estes LA, Suthipinijtham P. PMID: 18305940.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    20. Synergy of Irofulven in combination with various anti-metabolites, enzyme inhibitors, and miscellaneous agents in MV522 lung carcinoma cells: marked interaction with gemcitabine and 5-fluorouracil. Invest New Drugs. 2008 Oct; 26(5):407-15. Kelner MJ, McMorris TC, Rojas RJ, Estes LA, Suthipinijtham P. PMID: 18227973.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    21. Disruption of the ugt1 locus in mice resembles human Crigler-Najjar type I disease. J Biol Chem. 2008 Mar 21; 283(12):7901-11. Nguyen N, Bonzo JA, Chen S, Chouinard S, Kelner MJ, Hardiman G, Bélanger A, Tukey RH. PMID: 18180294.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansAnimals
    22. Synthesis and antitumor activity of amine analogs of irofulven. Bioorg Med Chem Lett. 2007 Dec 15; 17(24):6770-2. McMorris TC, Chimmani R, Gurram M, Staake MD, Kelner MJ. PMID: 17977722.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    23. Phase I/II study of continuous-infusion troxacitabine in refractory acute myeloid leukemia. J Clin Oncol. 2007 Jan 01; 25(1):10-5. Roboz GJ, Giles FJ, Ritchie EK, Allen-Bard S, Curcio TJ, Wilkes MA, Park SL, Kantarjian HM, Faderl S, Ravandi F, Kelner MJ, Feldman EJ. PMID: 17146106.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCTClinical Trials
    24. Structural organization of the murine microsomal glutathione S-transferase gene (MGST1) from the 129/SvJ strain: identification of the promoter region and a comprehensive examination of tissue expression. Biochim Biophys Acta. 2004 May 25; 1678(2-3):163-9. Kelner MJ, Bagnell RD, Morgenstern R. PMID: 15157743.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    25. Synthesis and biological activity of enantiomers of antitumor irofulven. J Org Chem. 2004 Feb 06; 69(3):619-23. McMorris TC, Staake MD, Kelner MJ. PMID: 14750783.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    26. Structure-activity relationship studies of illudins: analogues possessing a spiro-cyclobutane ring. J Org Chem. 2003 Dec 12; 68(25):9648-53. McMorris TC, Cong Q, Kelner MJ. PMID: 14656090.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    27. Basal expression of the human MAPEG members microsomal glutathione transferase 1 and prostaglandin E synthase genes is mediated by Sp1 and Sp3. Biochim Biophys Acta. 2003 Jun 19; 1627(2-3):79-84. Ekström L, Lyrenäs L, Jakobsson PJ, Morgenstern R, Kelner MJ. PMID: 12818425.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    28. Reaction of irofulven with zinc and acid. J Nat Prod. 2003 Feb; 66(2):310-2. McMorris TC, Moon SS, Kelner MJ. PMID: 12608875.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    29. Anti-tumour compounds illudin S and Irofulven induce DNA lesions ignored by global repair and exclusively processed by transcription- and replication-coupled repair pathways. DNA Repair (Amst). 2002 Dec 05; 1(12):1027-38. Jaspers NG, Raams A, Kelner MJ, Ng JM, Yamashita YM, Takeda S, McMorris TC, Hoeijmakers JH. PMID: 12531012.
      View in: PubMed   Mentions: 59     Fields:    Translation:HumansAnimalsCells
    30. Sesquiterpenes from Omphalotus illudens. Phytochemistry. 2002 Oct; 61(4):395-8. McMorris TC, Kashinatham A, Lira R, Rundgren H, Gantzel PK, Kelner MJ, Dawe R. PMID: 12377232.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    31. Enhanced antitumor activity of irofulven in combination with antimitotic agents. Invest New Drugs. 2002 Aug; 20(3):271-9. Kelner MJ, McMorris TC, Rojas RJ, Trani NA, Velasco TR, Estes LA, Suthipinijtham P. PMID: 12201490.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    32. Enhanced antitumor activity of irofulven in combination with thiotepa or mitomycin C. Cancer Chemother Pharmacol. 2002 May; 49(5):412-8. Kelner MJ, McMorris TC, Rojas RJ, Trani NA, Estes L. PMID: 11976836.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    33. Structure-activity studies of antitumor agent irofulven (hydroxymethylacylfulvene) and analogues. J Org Chem. 2001 Sep 07; 66(18):6158-63. McMorris TC, Yu J, Lira R, Dawe R, MacDonald JR, Waters SJ, Estes LA, Kelner MJ. PMID: 11529745.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    34. The effect of gamma hydroxybutyrate on serum osmolality. J Toxicol Clin Toxicol. 2001; 39(4):417-8. Ingels M, Kelner MJ, Clark RF. PMID: 11527239.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    35. Sesquiterpenes from the basidiomycete Omphalotus illudens. J Nat Prod. 2000 Nov; 63(11):1557-9. McMorris TC, Lira R, Gantzel PK, Kelner MJ, Dawe R. PMID: 11087609.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    36. Preparation and biological activity of amino acid and peptide conjugates of antitumor hydroxymethylacylfulvene. J Med Chem. 2000 Sep 21; 43(19):3577-80. McMorris TC, Yu J, Ngo HT, Wang H, Kelner MJ. PMID: 11000013.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    37. Structural organization of the human gastrointestinal glutathione peroxidase (GPX2) promoter and 3'-nontranscribed region: transcriptional response to exogenous redox agents. Gene. 2000 May 02; 248(1-2):109-16. Kelner MJ, Bagnell RD, Montoya MA, Lanham KA. PMID: 10806356.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    38. Structural organization of the microsomal glutathione S-transferase gene (MGST1) on chromosome 12p13.1-13.2. Identification of the correct promoter region and demonstration of transcriptional regulation in response to oxidative stress. J Biol Chem. 2000 Apr 28; 275(17):13000-6. Kelner MJ, Bagnell RD, Montoya MA, Estes LA, Forsberg L, Morgenstern R. PMID: 10777602.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    39. Structural organization of the human glutathione reductase gene: determination of correct cDNA sequence and identification of a mitochondrial leader sequence. Biochem Biophys Res Commun. 2000 Mar 16; 269(2):366-8. Kelner MJ, Montoya MA. PMID: 10708558.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    40. Efficacy of MGI 114 (HMAF) against the MRP+ metastatic MV522 lung carcinoma xenograft. Anticancer Drugs. 2000 Mar; 11(3):217-24. Kelner MJ, McMorris TC, Estes LA, Oval MY, Rojas RJ, Lynn JR, Lanham KA, Samson KM. PMID: 10831281.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    41. Anti-leukemic action of the novel agent MGI 114 (HMAF) and synergistic action with topotecan. Leukemia. 2000 Jan; 14(1):136-41. Kelner MJ, McMorris TC, Estes L, Samson KM, Trani NA, MacDonald JR. PMID: 10637489.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    42. Metabolism of antitumor hydroxymethylacylfulvene by rat liver cytosol. Drug Metab Dispos. 1999 Sep; 27(9):983-5. McMorris TC, Elayadi AN, Yu J, Hu Y, Kelner MJ. PMID: 10460795.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    43. Distribution of microsomal glutathione transferase 1 in mammalian tissues. A predominant alternate first exon in human tissues. Eur J Biochem. 1999 Mar; 260(2):409-13. Estonius M, Forsberg L, Danielsson O, Weinander R, Kelner MJ, Morgenstern R. PMID: 10095775.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    44. Metabolism of antitumor acylfulvene by rat liver cytosol. Biochem Pharmacol. 1999 Jan 01; 57(1):83-8. McMorris TC, Elayadi AN, Yu J, Kelner MJ. PMID: 9920288.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    45. Characterization of MGI 114 (HMAF) histiospecific toxicity in human tumor cell lines. Cancer Chemother Pharmacol. 1999; 44(3):235-40. Kelner MJ, McMorris TC, Montoya MA, Estes L, Uglik SF, Rutherford M, Samson KM, Bagnell RD, Taetle R. PMID: 10453725.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    46. Mice with a homozygous null mutation for the most abundant glutathione peroxidase, Gpx1, show increased susceptibility to the oxidative stress-inducing agents paraquat and hydrogen peroxide. J Biol Chem. 1998 Aug 28; 273(35):22528-36. de Haan JB, Bladier C, Griffiths P, Kelner M, O'Shea RD, Cheung NS, Bronson RT, Silvestro MJ, Wild S, Zheng SS, Beart PM, Hertzog PJ, Kola I. PMID: 9712879.
      View in: PubMed   Mentions: 109     Fields:    Translation:AnimalsCells
    47. Structural organization of the human selenium-dependent phospholipid hydroperoxide glutathione peroxidase gene (GPX4): chromosomal localization to 19p13.3. Biochem Biophys Res Commun. 1998 Aug 10; 249(1):53-5. Kelner MJ, Montoya MA. PMID: 9705830.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    48. Efficacy of MGI 114 (6-hydroxymethylacylfulvene, HMAF) against the mdr1/gp170 metastatic MV522 lung carcinoma xenograft. Eur J Cancer. 1998 May; 34(6):908-13. Kelner MJ, McMorris TC, Estes L, Samson KM, Bagnell RD, Taetle R. PMID: 9797706.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    49. Characterization of acylfulvene histiospecific toxicity in human tumor cell lines. Cancer Chemother Pharmacol. 1998; 41(3):237-42. Kelner MJ, McMorris TC, Montoya MA, Estes L, Uglik SF, Rutherford M, Samson KM, Bagnell RD, Taetle R. PMID: 9443641.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    50. Design and Synthesis of Antitumor Acylfulvenes. J Org Chem. 1997 May 02; 62(9):3015-3018. McMorris TC, Yu J, Hu Y, Estes LA, Kelner MJ. PMID: 11671671.
      View in: PubMed   Mentions: 2     Fields:    
    51. Preclinical antitumor activity of 6-hydroxymethylacylfulvene, a semisynthetic derivative of the mushroom toxin illudin S. Cancer Res. 1997 Jan 15; 57(2):279-83. MacDonald JR, Muscoplat CC, Dexter DL, Mangold GL, Chen SF, Kelner MJ, McMorris TC, Von Hoff DD. PMID: 9000568.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    52. Characterization of cellular accumulation and toxicity of illudin S in sensitive and nonsensitive tumor cells. Cancer Chemother Pharmacol. 1997; 40(1):65-71. Kelner MJ, McMorris TC, Montoya MA, Estes L, Rutherford M, Samson KM, Taetle R. PMID: 9137532.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    53. Heterologous expression of carbonyl reductase: demonstration of prostaglandin 9-ketoreductase activity and paraquat resistance. Life Sci. 1997; 61(23):2317-22. Kelner MJ, Estes L, Rutherford M, Uglik SF, Peitzke JA. PMID: 9408054.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    54. Reactive oxygen species and their contribution to pathology in Down syndrome. Adv Pharmacol. 1997; 38:379-402. de Haan JB, Wolvetang EJ, Cristiano F, Iannello R, Bladier C, Kelner MJ, Kola I. PMID: 8895817.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    55. (Hydroxymethyl)acylfulvene: an illudin derivative with superior antitumor properties. J Nat Prod. 1996 Sep; 59(9):896-9. McMorris TC, Kelner MJ, Wang W, Yu J, Estes LA, Taetle R. PMID: 8864242.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    56. Structural organization of the human microsomal glutathione S-transferase gene (GST12). Genomics. 1996 Aug 15; 36(1):100-3. Kelner MJ, Stokely MN, Stovall NE, Montoya MA. PMID: 8812420.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    57. Elevation in the ratio of Cu/Zn-superoxide dismutase to glutathione peroxidase activity induces features of cellular senescence and this effect is mediated by hydrogen peroxide. Hum Mol Genet. 1996 Feb; 5(2):283-92. de Haan JB, Cristiano F, Iannello R, Bladier C, Kelner MJ, Kola I. PMID: 8824885.
      View in: PubMed   Mentions: 53     Fields:    Translation:HumansCells
    58. Acylfulvenes, a new class of potent antitumor agents. Experientia. 1996 Jan 16; 52(1):75-80. McMorris TC, Kelner MJ, Wang W, Diaz MA, Estes LA, Taetle R. PMID: 8575564.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimals
    59. Efficacy of HMAF (MGI-114) in the MV522 metastatic lung carcinoma xenograft model nonresponsive to traditional anticancer agents. Invest New Drugs. 1996; 14(2):161-7. Kelner MJ, McMorris TC, Estes L, Wang W, Samson KM, Taetle R. PMID: 8913837.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    60. Efficacy of Acylfulvene Illudin analogues against a metastatic lung carcinoma MV522 xenograft nonresponsive to traditional anticancer agents: retention of activity against various mdr phenotypes and unusual cytotoxicity against ERCC2 and ERCC3 DNA helicase-deficient cells. Cancer Res. 1995 Nov 01; 55(21):4936-40. Kelner MJ, McMorris TC, Estes L, Starr RJ, Rutherford M, Montoya M, Samson KM, Taetle R. PMID: 7585533.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    61. Heterologous expression of selenium-dependent glutathione peroxidase affords cellular resistance to paraquat. Arch Biochem Biophys. 1995 Oct 20; 323(1):40-6. Kelner MJ, Bagnell RD, Uglik SF, Montoya MA, Mullenbach GT. PMID: 7487071.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    62. Superoxide dismutase abolishes the platelet-derived growth factor-induced release of prostaglandin E2 by blocking induction of nitric oxide synthase: role of superoxide. Arch Biochem Biophys. 1995 Sep 10; 322(1):31-8. Kelner MJ, Uglik SF. PMID: 7574691.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    63. In vitro and in vivo studies on the anticancer activity of dehydroilludin M. Anticancer Res. 1995 May-Jun; 15(3):873-8. Kelner MJ, McMorris TC, Taetle R. PMID: 7645974.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    64. Nonresponsiveness of the metastatic human lung carcinoma MV522 xenograft to conventional anticancer agents. Anticancer Res. 1995 May-Jun; 15(3):867-71. Kelner MJ, McMorris TC, Estes L, Starr R, Samson K, Varki N, Taetle R. PMID: 7645973.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    65. Transfection with human copper-zinc superoxide dismutase induces bidirectional alterations in other antioxidant enzymes, proteins, growth factor response, and paraquat resistance. Free Radic Biol Med. 1995 Mar; 18(3):497-506. Kelner MJ, Bagnell R, Montoya M, Estes L, Uglik SF, Cerutti P. PMID: 9101240.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    66. Characterization of illudin S sensitivity in DNA repair-deficient Chinese hamster cells. Unusually high sensitivity of ERCC2 and ERCC3 DNA helicase-deficient mutants in comparison to other chemotherapeutic agents. Biochem Pharmacol. 1994 Jul 19; 48(2):403-9. Kelner MJ, McMorris TC, Estes L, Rutherford M, Montoya M, Goldstein J, Samson K, Starr R, Taetle R. PMID: 8053936.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    67. Mechanism of prostaglandin E2 release and increase in PGH2/PGE2 isomerase activity by PDGF: involvement of nitric oxide. Arch Biochem Biophys. 1994 Jul; 312(1):240-3. Kelner MJ, Uglik SF. PMID: 7518221.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    68. PDGF-induces the glutathione-dependent enzyme PGH2/PGE2 isomerase in NIH3T3 and pEJ transformed fibroblasts. Biochem Biophys Res Commun. 1994 Jan 14; 198(1):298-303. Kelner MJ, Uglik SF. PMID: 8292033.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    69. Thioureas and thioamides react with superoxide to form a novel product. Free Radic Biol Med. 1993 Feb; 14(2):225-6. Kelner MJ. PMID: 8381108.
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    70. HPLC determination of a new anticancer agent (acylfulvene) in serum. Neoplasma. 1992; 39(6):369-73. Brandsteterová E, Kelner MJ, McMorris TC, Estes L, Bagnell R, Montoya M. PMID: 1491727.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    71. Alteration of growth rate and fibronectin by imbalances in superoxide dismutase and glutathione peroxidase activity. Adv Exp Med Biol. 1991; 283:305-9. Kelner MJ, Bagnell R. PMID: 2069002.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    72. On the mechanism of toxicity of illudins: the role of glutathione. Chem Res Toxicol. 1990 Nov-Dec; 3(6):574-9. McMorris TC, Kelner MJ, Wang W, Moon S, Taetle R. PMID: 2103329.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    73. Preclinical evaluation of illudins as anticancer agents: basis for selective cytotoxicity. J Natl Cancer Inst. 1990 Oct 03; 82(19):1562-5. Kelner MJ, McMorris TC, Taetle R. PMID: 2402017.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    74. Alteration of endogenous glutathione peroxidase, manganese superoxide dismutase, and glutathione transferase activity in cells transfected with a copper-zinc superoxide dismutase expression vector. Explanation for variations in paraquat resistance. J Biol Chem. 1990 Jul 05; 265(19):10872-5. Kelner MJ, Bagnell R. PMID: 2358446.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    75. Thioureas react with superoxide radicals to yield a sulfhydryl compound. Explanation for protective effect against paraquat. J Biol Chem. 1990 Jan 25; 265(3):1306-11. Kelner MJ, Bagnell R, Welch KJ. PMID: 2153125.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    76. Glutathione-dependent enzymes alone can produce paraquat resistance. Free Radic Biol Med. 1990; 9(2):149-53. Kelner MJ, Bagnell R. PMID: 2172100.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    77. Paraquat resistance associated with reduced NADPH reductase in an energy-dependent paraquat-accumulating cell line. Arch Biochem Biophys. 1989 Nov 01; 274(2):366-74. Kelner MJ, Bagnell R. PMID: 2802616.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    78. Inactivation of intracellular copper-zinc superoxide dismutase by copper chelating agents without glutathione depletion and methemoglobin formation. Free Radic Biol Med. 1989; 6(4):355-60. Kelner MJ, Bagnell R, Hale B, Alexander NM. PMID: 2540068.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    79. Definitive liquid-chromatographic demonstration that N-ethylglycine is the metabolite of lidocaine that interferes in the Kodak sarcosine oxidase-coupled method for creatinine. Clin Chem. 1988 Dec; 34(12):2569-72. Roberts RT, Alexander NM, Kelner MJ. PMID: 3197304.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    80. Methylene blue competes with paraquat for reduction by flavo-enzymes resulting in decreased superoxide production in the presence of heme proteins. Arch Biochem Biophys. 1988 May 01; 262(2):422-6. Kelner MJ, Bagnell R, Hale B, Alexander NM. PMID: 2835006.
      View in: PubMed   Mentions: 17     Fields:    Translation:Cells
    81. Potential of methylene blue to block oxygen radical generation in reperfusion injury. Basic Life Sci. 1988; 49:895-8. Kelner MJ, Bagnell R, Hale B, Alexander NM. PMID: 2855011.
      View in: PubMed   Mentions: 17     Fields:    Translation:Animals
    82. Newer cardiac agents: antiarrhythmics and antianginal agents. Clin Lab Med. 1987 Sep; 7(3):567-85. Kelner MJ. PMID: 3308297.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    83. Preclinical evaluation of illudins as anticancer agents. Cancer Res. 1987 Jun 15; 47(12):3186-9. Kelner MJ, McMorris TC, Beck WT, Zamora JM, Taetle R. PMID: 3472654.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    84. Endocrine hormone abnormalities in Amanita poisoning. J Toxicol Clin Toxicol. 1987; 25(1-2):21-37. Kelner MJ, Alexander NM. PMID: 3586085.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    85. Thiol stimulation of the cytochrome P-450-dependent reduction of 1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane (DDT) to 1,1-dichloro-2,2-bis(p-chlorophenyl)ethane (DDD). Biochem Pharmacol. 1986 Jun 01; 35(11):1805-7. Kelner MJ, McLenithan JC, Anders MW. PMID: 3718529.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    86. Oxidation of glutathione by methylene blue is equivalent in G-6-PD deficient and normal erythrocytes. Res Commun Chem Pathol Pharmacol. 1986 May; 52(2):265-8. Kelner MJ, Alexander NM. PMID: 3715203.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    87. Inhibition of erythrocyte superoxide dismutase by diethyldithiocarbamate also results in oxyhemoglobin-catalyzed glutathione depletion and methemoglobin production. J Biol Chem. 1986 Feb 05; 261(4):1636-41. Kelner MJ, Alexander NM. PMID: 3003078.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    88. In vitro oxidation of uric acid in serum by methylene blue. Clin Chem. 1986 Jan; 32(1 Pt 1):177-9. Andranovich T, Kelner MJ. PMID: 3940703.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    89. Methylene blue directly oxidizes glutathione without the intermediate formation of hydrogen peroxide. J Biol Chem. 1985 Dec 05; 260(28):15168-71. Kelner MJ, Alexander NM. PMID: 4066667.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    90. Mismeasurement of methemoglobin ("methemoglobin revisited") Clin Chem. 1985 Jan; 31(1):168-9. Kelner MJ, Bailey DN. PMID: 3965210.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    91. Rapid separation and identification of myoglobin and hemoglobin in urine by centrifugation through a microconcentrator membrane. Clin Chem. 1985 Jan; 31(1):112-4. Kelner MJ, Alexander NM. PMID: 3965185.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    92. Positive diphenhydramine interference in the EMIT-d.a.u. assay. Clin Chem. 1984 Aug; 30(8):1430. Kelner MJ. PMID: 6378429.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    93. Micro-analysis for quinidine in serum by thin-layer chromatography followed by fluorescence densitometry. Clin Chem. 1983 Dec; 29(12):2100-2. Kelner M, Bailey DN. PMID: 6640909.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    94. Reversed-phase liquid-chromatographic simultaneous analysis for thiopental and pentobarbital in serum. Clin Chem. 1983 Jun; 29(6):1097-100. Kelner M, Bailey DN. PMID: 6851102.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
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