William Gerwick

Title(s)Professor, School of Pharmacy and Pharmaceutical Science
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
vCardDownload vCard

    Collapse Research 
    Collapse Research Activities and Funding
    Development of an efficient cyanobacterial platform for heterologous expression and biosynthetic interrogations of natural products.
    NIH R01GM118815Jan 12, 2017 - Dec 31, 2020
    Role: Principal Investigator
    Development of Gallinamide A-Inspired Agents for the Treatment of Chagas? Disease
    NIH R21AI127505Dec 7, 2016 - Nov 30, 2019
    Role: Principal Investigator
    Unified Computation Tools for Natural Products Research
    NIH R01GM107550Sep 5, 2013 - Apr 30, 2025
    Role: Principal Investigator
    Huntington's Disease Natural Product Drug Discovery
    NIH R21AG038772Sep 1, 2011 - Aug 31, 2015
    Role: Principal Investigator
    Biosynthetic Analysis of Marine Cyanobacterial Pathways
    NIH R01CA108874Jul 1, 2004 - Mar 31, 2017
    Role: Principal Investigator
    ICBG: Training, Conservation and Drug Discovery using Panamanian Microorganisms
    NIH U01TW006634Sep 27, 2003 - Apr 30, 2015
    Role: Principal Investigator
    Training Program in Marine Biotechnology
    NIH T32GM067550Jul 1, 2003 - Jun 30, 2021
    Role: Principal Investigator
    US-Japan Seminar on Marine Bioorganic Chemistry
    NIH R13CA102377Jun 1, 2003 - May 31, 2004
    Role: Principal Investigator
    Neurotoxins from Marine Algae and Cyanobacteria
    NIH R01NS053398Jul 1, 2001 - Jun 30, 2017
    Role: Principal Investigator
    Neurotoxins from Marine Algae and Cyanobacteria
    NIH R01GM063554Jul 1, 2001 - Jun 30, 2005
    Role: Principal Investigator
    EICOSANOID BIOSYNTHESIS IN MARINE PLANTS
    NIH F06TW001616Jun 21, 1991
    Role: Principal Investigator
    Targeted Discovery of Marine-derived Anticancer Leads
    NIH U19CA052955Sep 1, 1990 - Apr 30, 2012
    Role: Co-Investigator
    SMALL INSTRUMENTATION PROGRAM
    NIH S15ES005267Aug 15, 1989 - Jul 31, 1990
    Role: Principal Investigator
    ANTINEOPLASTIC AGENTS FROM BLUE GREEN ALGAE
    NIH R23CA042850Jul 1, 1986 - Jun 30, 1990
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Light-gated Integrator for Highlighting Kinase Activity in Living Cells. bioRxiv. 2024 Mar 20. Lin W, Phatarphekar A, Zhong Y, Liu L, Kwon HB, Gerwick WH, Wang Y, Mehta S, Zhang J. PMID: 38562887; PMCID: PMC10983958.
      View in: PubMed   Mentions:
    2. PECAN Predicts Patterns of Cancer Cell Cytostatic Activity of Natural Products Using Deep Learning. J Nat Prod. 2024 Mar 22; 87(3):567-575. Gahl M, Kim HW, Glukhov E, Gerwick WH, Cottrell GW. PMID: 38349959; PMCID: PMC10960629.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    3. Structure and Biosynthesis of Hectoramide B, a Linear Depsipeptide from Marine Cyanobacterium Moorena producens JHB Discovered via Coculture with Candida albicans. ACS Chem Biol. 2024 Mar 15; 19(3):619-628. Ngo TE, Ecker A, Ryu B, Guild A, Remmel A, Boudreau PD, Alexander KL, Naman CB, Glukhov E, Avalon NE, Shende VV, Thomas L, Dahesh S, Nizet V, Gerwick L, Gerwick WH. PMID: 38330248; PMCID: PMC10949194.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    4. microbeMASST: a taxonomically informed mass spectrometry search tool for microbial metabolomics data. Nat Microbiol. 2024 Feb; 9(2):336-345. Zuffa S, Schmid R, Bauermeister A, P Gomes PW, Caraballo-Rodriguez AM, El Abiead Y, Aron AT, Gentry EC, Zemlin J, Meehan MJ, Avalon NE, Cichewicz RH, Buzun E, Terrazas MC, Hsu CY, Oles R, Ayala AV, Zhao J, Chu H, Kuijpers MCM, Jackrel SL, Tugizimana F, Nephali LP, Dubery IA, Madala NE, Moreira EA, Costa-Lotufo LV, Lopes NP, Rezende-Teixeira P, Jimenez PC, Rimal B, Patterson AD, Traxler MF, Pessotti RC, Alvarado-Villalobos D, Tamayo-Castillo G, Chaverri P, Escudero-Leyva E, Quiros-Guerrero LM, Bory AJ, Joubert J, Rutz A, Wolfender JL, Allard PM, Sichert A, Pontrelli S, Pullman BS, Bandeira N, Gerwick WH, Gindro K, Massana-Codina J, Wagner BC, Forchhammer K, Petras D, Aiosa N, Garg N, Liebeke M, Bourceau P, Kang KB, Gadhavi H, de Carvalho LPS, Silva Dos Santos M, Pérez-Lorente AI, Molina-Santiago C, Romero D, Franke R, Brönstrup M, Vera Ponce de León A, Pope PB, La Rosa SL, La Barbera G, Roager HM, Laursen MF, Hammerle F, Siewert B, Peintner U, Licona-Cassani C, Rodriguez-Orduña L, Rampler E, Hildebrand F, Koellensperger G, Schoeny H, Hohenwallner K, Panzenboeck L, Gregor R, O'Neill EC, Roxborough ET, Odoi J, Bale NJ, Ding S, Sinninghe Damsté JS, Guan XL, Cui JJ, Ju KS, Silva DB, Silva FMR, da Silva GF, Koolen HHF, Grundmann C, Clement JA, Mohimani H, Broders K, McPhail KL, Ober-Singleton SE, Rath CM, McDonald D, Knight R, Wang M, Dorrestein PC. PMID: 38316926; PMCID: PMC10847041.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    5. Orthogonal Deprotection Strategy of Fmoc Provides Improved Synthesis of Sensitive Peptides: Application to Z-Arg-Lys-AOMK. ACS Omega. 2024 Jan 23; 9(3):3997-4003. Almaliti J, Alhindy M, Yoon MC, Hook V, Molinski TF, O'Donoghue AJ, Gerwick WH. PMID: 38284081; PMCID: PMC10809369.
      View in: PubMed   Mentions:
    6. Open access repository-scale propagated nearest neighbor suspect spectral library for untargeted metabolomics. Nat Commun. 2023 Dec 20; 14(1):8488. Bittremieux W, Avalon NE, Thomas SP, Kakhkhorov SA, Aksenov AA, Gomes PWP, Aceves CM, Caraballo-Rodríguez AM, Gauglitz JM, Gerwick WH, Huan T, Jarmusch AK, Kaddurah-Daouk RF, Kang KB, Kim HW, Kondic T, Mannochio-Russo H, Meehan MJ, Melnik AV, Nothias LF, O'Donovan C, Panitchpakdi M, Petras D, Schmid R, Schymanski EL, van der Hooft JJJ, Weldon KC, Yang H, Xing S, Zemlin J, Wang M, Dorrestein PC. PMID: 38123557; PMCID: PMC10733301.
      View in: PubMed   Mentions: 3     Fields:    
    7. Lake Avernus Has Turned Red: Bioindicator Monitoring Unveils the Secrets of "Gates of Hades". Toxins (Basel). 2023 12 13; 15(12). Esposito G, Glukhov E, Gerwick WH, Medio G, Teta R, Lega M, Costantino V. PMID: 38133202; PMCID: PMC10747548.
      View in: PubMed   Mentions:    Fields:    Translation:CellsPHPublic Health
    8. Covalent Macrocyclic Proteasome Inhibitors Mitigate Resistance in Plasmodium falciparum. ACS Infect Dis. 2023 Oct 13; 9(10):2036-2047. Bennett JM, Ward KE, Muir RK, Kabeche S, Yoo E, Yeo T, Lam G, Zhang H, Almaliti J, Berger G, Faucher FF, Lin G, Gerwick WH, Yeh E, Fidock DA, Bogyo M. PMID: 37712594; PMCID: PMC10591878.
      View in: PubMed   Mentions:    Fields:    
    9. Artificial intelligence for natural product drug discovery. Nat Rev Drug Discov. 2023 11; 22(11):895-916. Mullowney MW, Duncan KR, Elsayed SS, Garg N, van der Hooft JJJ, Martin NI, Meijer D, Terlouw BR, Biermann F, Blin K, Durairaj J, Gorostiola González M, Helfrich EJN, Huber F, Leopold-Messer S, Rajan K, de Rond T, van Santen JA, Sorokina M, Balunas MJ, Beniddir MA, van Bergeijk DA, Carroll LM, Clark CM, Clevert DA, Dejong CA, Du C, Ferrinho S, Grisoni F, Hofstetter A, Jespers W, Kalinina OV, Kautsar SA, Kim H, Leao TF, Masschelein J, Rees ER, Reher R, Reker D, Schwaller P, Segler M, Skinnider MA, Walker AS, Willighagen EL, Zdrazil B, Ziemert N, Goss RJM, Guyomard P, Volkamer A, Gerwick WH, Kim HU, Müller R, van Wezel GP, van Westen GJP, Hirsch AKH, Linington RG, Robinson SL, Medema MH. PMID: 37697042.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    10. Enzymatic Halogenation of Terminal Alkynes. J Am Chem Soc. 2023 08 30; 145(34):18716-18721. Lukowski AL, Hubert FM, Ngo TE, Avalon NE, Gerwick WH, Moore BS. PMID: 37594919; PMCID: PMC10486310.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    11. Structural elucidation of recombinant Trichomonas vaginalis 20S proteasome bound to covalent inhibitors. bioRxiv. 2023 Aug 17. Silhan J, Fajtova P, Bartosova J, Hurysz BM, Almaliti J, Miyamoto Y, Eckmann L, Gerwick WH, O'Donoghue AJ, Boura E. PMID: 37645851; PMCID: PMC10462138.
      View in: PubMed   Mentions:
    12. DeepSAT: Learning Molecular Structures from Nuclear Magnetic Resonance Data. J Cheminform. 2023 Aug 07; 15(1):71. Kim HW, Zhang C, Reher R, Wang M, Alexander KL, Nothias LF, Han YK, Shin H, Lee KY, Lee KH, Kim MJ, Dorrestein PC, Gerwick WH, Cottrell GW. PMID: 37550756; PMCID: PMC10406729.
      View in: PubMed   Mentions:
    13. Evaluation of bumetanide as a potential therapeutic agent for Alzheimer's disease. Front Pharmacol. 2023; 14:1190402. Boyarko B, Podvin S, Greenberg B, Momper JD, Huang Y, Gerwick WH, Bang AG, Quinti L, Griciuc A, Kim DY, Tanzi RE, Feldman HH, Hook V. PMID: 37601062; PMCID: PMC10436590.
      View in: PubMed   Mentions: 1  
    14. A Taxonomically-informed Mass Spectrometry Search Tool for Microbial Metabolomics Data. Res Sq. 2023 Aug 03. Zuffa S, Schmid R, Bauermeister A, Gomes PWP, Caraballo-Rodriguez AM, Abiead YE, Aron AT, Gentry EC, Zemlin J, Meehan MJ, Avalon NE, Cichewicz RH, Buzun E, Terrazas MC, Hsu CY, Oles R, Ayala AV, Zhao J, Chu H, Kuijpers MCM, Jackrel SL, Tugizimana F, Nephali LP, Dubery IA, Madala NE, Moreira EA, Costa-Lotufo LV, Lopes NP, Rezende-Teixeira P, Jimenez PC, Rimal B, Patterson AD, Traxler MF, de Cassia Pessotti R, Alvarado-Villalobos D, Tamayo-Castillo G, Chaverri P, Escudero-Leyva E, Quiros-Guerrero LM, Bory AJ, Joubert J, Rutz A, Wolfender JL, Allard PM, Sichert A, Pontrelli S, Pullman BS, Bandeira N, Gerwick WH, Gindro K, Massana-Codina J, Wagner BC, Forchhammer K, Petras D, Aiosa N, Garg N, Liebeke M, Bourceau P, Kang KB, Gadhavi H, de Carvalho LPS, Dos Santos MS, Pérez-Lorente AI, Molina-Santiago C, Romero D, Franke R, Brönstrup M, de León AVP, Pope PB, Rosa SL, Barbera G, Roager HM, Laursen MF, Hammerle F, Siewert B, Peintner U, Licona-Cassani C, Rodriguez-Orduña L, Rampler E, Hildebrand F, Koellensperger G, Schoeny H, Hohenwallner K, Panzenboeck L, Gregor R, O'Neill EC, Roxborough ET, Odoi J, Bale NJ, Ding S, Sinninghe Damsté JS, Guan XL, Cui JJ, Ju KS, Silva DB, Silva FMR, da Silva GF, Koolen HHF, Grundmann C, Clement JA, Mohimani H, Broders K, McPhail KL, Ober-Singleton SE, Rath CM, McDonald D, Knight R, Wang M, Dorrestein PC. PMID: 37577622; PMCID: PMC10418563.
      View in: PubMed   Mentions:
    15. Structure and Biosynthesis of Hectoramide B, a Linear Depsipeptide from the Marine Cyanobacterium Moorena producens JHB Discovered via Co-culture with Candida albicans. bioRxiv. 2023 Jul 06. Ngo TE, Ecker A, Guild A, Remmel A, Boudreau PD, Alexander KL, Naman CB, Glukhov E, Avalon NE, Shende VV, Gerwick L, Gerwick WH. PMID: 37461655; PMCID: PMC10350029.
      View in: PubMed   Mentions:
    16. Methods in marine natural product drug discovery: what's new? Expert Opin Drug Discov. 2023 07; 18(7):687-691. Almaliti J, Gerwick WH. PMID: 37194298.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    17. Development of subunit selective substrates for Trichomonas vaginalis proteasome. bioRxiv. 2023 Apr 06. Fajtova P, Hurysz BM, Miyamoto Y, Serafim M, Jiang Z, Trujillo DF, Liu L, Somani U, Almaliti J, Myers SA, Caffrey CR, Gerwick WH, Kirk CJ, Boura E, Eckmann L, O'Donoghue AJ. PMID: 37066163; PMCID: PMC10104049.
      View in: PubMed   Mentions:
    18. Mitigating the risk of antimalarial resistance via covalent dual-subunit inhibition of the Plasmodium proteasome. Cell Chem Biol. 2023 05 18; 30(5):470-485.e6. Deni I, Stokes BH, Ward KE, Fairhurst KJ, Pasaje CFA, Yeo T, Akbar S, Park H, Muir R, Bick DS, Zhan W, Zhang H, Liu YJ, Ng CL, Kirkman LA, Almaliti J, Gould AE, Duffey M, O'Donoghue AJ, Uhlemann AC, Niles JC, da Fonseca PCA, Gerwick WH, Lin G, Bogyo M, Fidock DA. PMID: 36963402; PMCID: PMC10198959.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    19. Development of Potent and Highly Selective Epoxyketone-Based Plasmodium Proteasome Inhibitors. Chemistry. 2023 Apr 06; 29(20):e202203958. Almaliti J, Fajtová P, Calla J, LaMonte GM, Feng M, Rocamora F, Ottilie S, Glukhov E, Boura E, Suhandynata RT, Momper JD, Gilson MK, Winzeler EA, Gerwick WH, O'Donoghue AJ. PMID: 36617500; PMCID: PMC10894724.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    20. Kalkitoxin: A Potent Suppressor of Distant Breast Cancer Metastasis. Int J Mol Sci. 2023 Jan 07; 24(2). Shrestha SK, Min KH, Kim SW, Kim H, Gerwick WH, Soh Y. PMID: 36674719.
      View in: PubMed   Mentions: 1     Fields:    
    21. Rapid Biotic and Abiotic Transformation of Toxins produced by Ostreopsis. cf. ovata. Mar Drugs. 2022 Nov 28; 20(12). Ternon E, Thomas OP, Lemée R, Gerwick WH. PMID: 36547895; PMCID: PMC9787646.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    22. NPOmix: A machine learning classifier to connect mass spectrometry fragmentation data to biosynthetic gene clusters. PNAS Nexus. 2022 Nov; 1(5):pgac257. Leão TF, Wang M, da Silva R, Gurevich A, Bauermeister A, Gomes PWP, Brejnrod A, Glukhov E, Aron AT, Louwen JJR, Kim HW, Reher R, Fiore MF, van der Hooft JJJ, Gerwick L, Gerwick WH, Bandeira N, Dorrestein PC. PMID: 36712343; PMCID: PMC9802219.
      View in: PubMed   Mentions: 2  
    23. Native metabolomics identifies the rivulariapeptolide family of protease inhibitors. Nat Commun. 2022 08 08; 13(1):4619. Reher R, Aron AT, Fajtová P, Stincone P, Wagner B, Pérez-Lorente AI, Liu C, Shalom IYB, Bittremieux W, Wang M, Jeong K, Matos-Hernandez ML, Alexander KL, Caro-Diaz EJ, Naman CB, Scanlan JHW, Hochban PMM, Diederich WE, Molina-Santiago C, Romero D, Selim KA, Sass P, Brötz-Oesterhelt H, Hughes CC, Dorrestein PC, O'Donoghue AJ, Gerwick WH, Petras D. PMID: 35941113; PMCID: PMC9358669.
      View in: PubMed   Mentions: 6     Fields:    
    24. Discovery of Novel Tyrosinase Inhibitors From Marine Cyanobacteria. Front Microbiol. 2022; 13:912621. He Y, Suyama TL, Kim H, Glukhov E, Gerwick WH. PMID: 35910604; PMCID: PMC9329053.
      View in: PubMed   Mentions:
    25. Discovery of pH-Selective Marine and Plant Natural Product Inhibitors of Cathepsin B Revealed by Screening at Acidic and Neutral pH Conditions. ACS Omega. 2022 Jul 26; 7(29):25346-25352. Phan VV, Mosier C, Yoon MC, Glukhov E, Caffrey CR, O'Donoghue AJ, Gerwick WH, Hook V. PMID: 35910167; PMCID: PMC9330179.
      View in: PubMed   Mentions:
    26. Hippo pathway regulation by phosphatidylinositol transfer protein and phosphoinositides. Nat Chem Biol. 2022 10; 18(10):1076-1086. Li FL, Fu V, Liu G, Tang T, Konradi AW, Peng X, Kemper E, Cravatt BF, Franklin JM, Wu Z, Mayfield J, Dixon JE, Gerwick WH, Guan KL. PMID: 35788180.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    27. Heterologous Expression in Anabaena of the Columbamide Pathway from the Cyanobacterium Moorena bouillonii and Production of New Analogs. ACS Chem Biol. 2022 07 15; 17(7):1910-1923. Taton A, Rohrer S, Diaz B, Reher R, Caraballo Rodriguez AM, Pierce ML, Dorrestein PC, Gerwick L, Gerwick WH, Golden JW. PMID: 35761435.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    28. Secondary Metabolite Variation and Bioactivities of Two Marine Aspergillus Strains in Static Co-Culture Investigated by Molecular Network Analysis and Multiple Database Mining Based on LC-PDA-MS/MS. Antibiotics (Basel). 2022 Apr 12; 11(4). Wang Y, Glukhov E, He Y, Liu Y, Zhou L, Ma X, Hu X, Hong P, Gerwick WH, Zhang Y. PMID: 35453264; PMCID: PMC9031932.
      View in: PubMed   Mentions: 9  
    29. On the Hunt for New Toxin Families Produced by a Mediterranean Strain of the Benthic Dinoflagellate Ostreopsis cf. ovata. Toxins (Basel). 2022 03 23; 14(4). Ternon E, Glukhov E, Trytten E, Lemée R, Gerwick WH. PMID: 35448843; PMCID: PMC9030729.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    30. Antillatoxin-Stimulated Neurite Outgrowth Involves the Brain-Derived Neurotrophic Factor (BDNF) - Tropomyosin Related Kinase B (TrkB) Signaling Pathway. J Nat Prod. 2022 03 25; 85(3):562-571. Mehrotra S, Pierce ML, Cao Z, Jabba SV, Gerwick WH, Murray TF. PMID: 35239341; PMCID: PMC9245549.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    31. Intramolecular Interactions Enhance the Potency of Gallinamide A Analogues against Trypanosoma cruzi. J Med Chem. 2022 03 10; 65(5):4255-4269. Barbosa Da Silva E, Sharma V, Hernandez-Alvarez L, Tang AH, Stoye A, O'Donoghue AJ, Gerwick WH, Payne RJ, McKerrow JH, Podust LM. PMID: 35188371.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    32. Adaptive laboratory evolution in S. cerevisiae highlights role of transcription factors in fungal xenobiotic resistance. Commun Biol. 2022 02 11; 5(1):128. Ottilie S, Luth MR, Hellemann E, Goldgof GM, Vigil E, Kumar P, Cheung AL, Song M, Godinez-Macias KP, Carolino K, Yang J, Lopez G, Abraham M, Tarsio M, LeBlanc E, Whitesell L, Schenken J, Gunawan F, Patel R, Smith J, Love MS, Williams RM, McNamara CW, Gerwick WH, Ideker T, Suzuki Y, Wirth DF, Lukens AK, Kane PM, Cowen LE, Durrant JD, Winzeler EA. PMID: 35149760; PMCID: PMC8837787.
      View in: PubMed   Mentions: 6  Translation:Animals
    33. Molecular Features of CA-074 pH-Dependent Inhibition of Cathepsin B. Biochemistry. 2022 02 15; 61(4):228-238. Yoon MC, Christy MP, Phan VV, Gerwick WH, Hook G, O'Donoghue AJ, Hook V. PMID: 35119840; PMCID: PMC9096814.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    34. SMART-Miner: A convolutional neural network-based metabolite identification from 1 H-13 C HSQC spectra. Magn Reson Chem. 2022 Nov; 60(11):1070-1075. Kim HW, Zhang C, Cottrell GW, Gerwick WH. PMID: 34928526.
      View in: PubMed   Mentions: 7     Fields:    
    35. Luquilloamides, Cytotoxic Lipopeptides from a Puerto Rican Collection of the Filamentous Marine Cyanobacterium Oscillatoria sp. J Org Chem. 2022 01 21; 87(2):1043-1055. Kim GJ, Mascuch SJ, Mevers E, Boudreau PD, Gerwick WH, Choi H. PMID: 34967649.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    36. Potent Anti-SARS-CoV-2 Activity by the Natural Product Gallinamide A and Analogues via Inhibition of Cathepsin L. J Med Chem. 2022 02 24; 65(4):2956-2970. Ashhurst AS, Tang AH, Fajtová P, Yoon MC, Aggarwal A, Bedding MJ, Stoye A, Beretta L, Pwee D, Drelich A, Skinner D, Li L, Meek TD, McKerrow JH, Hook V, Tseng CT, Larance M, Turville S, Gerwick WH, O'Donoghue AJ, Payne RJ. PMID: 34730959; PMCID: PMC8577376.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    37. NPClassifier: A Deep Neural Network-Based Structural Classification Tool for Natural Products. J Nat Prod. 2021 11 26; 84(11):2795-2807. Kim HW, Wang M, Leber CA, Nothias LF, Reher R, Kang KB, van der Hooft JJJ, Dorrestein PC, Gerwick WH, Cottrell GW. PMID: 34662515; PMCID: PMC8631337.
      View in: PubMed   Mentions: 64     Fields:    Translation:Cells
    38. First Total Synthesis and Structure-Activity Relationship of Iheyamide A, an Antitrypanosomal Linear Peptide Isolated from a Dapis sp. Marine Cyanobacterium. J Nat Prod. 2021 09 24; 84(9):2587-2593. Iwasaki A, Teranuma K, Kurisawa N, Rahmawati Y, Jeelani G, Nozaki T, Gerwick WH, Suenaga K. PMID: 34488344.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    39. Selective Neutral pH Inhibitor of Cathepsin B Designed Based on Cleavage Preferences at Cytosolic and Lysosomal pH Conditions. ACS Chem Biol. 2021 09 17; 16(9):1628-1643. Yoon MC, Solania A, Jiang Z, Christy MP, Podvin S, Mosier C, Lietz CB, Ito G, Gerwick WH, Wolan DW, Hook G, O'Donoghue AJ, Hook V. PMID: 34416110; PMCID: PMC9104225.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    40. SIRT1 Activation Enhancing 8,3'-Neolignans from the Twigs of Corylopsis coreana Uyeki. Plants (Basel). 2021 Aug 16; 10(8). Kim HW, Jeon JB, Zhang M, Cho HM, Ryu B, Lee BW, Gerwick WH, Oh WK. PMID: 34451729; PMCID: PMC8398912.
      View in: PubMed   Mentions:
    41. Portobelamides A and B and Caciqueamide, Cytotoxic Peptidic Natural Products from a Caldora sp. Marine Cyanobacterium. J Nat Prod. 2021 08 27; 84(8):2081-2093. Demirkiran O, Almaliti J, Leão T, Navarro G, Byrum T, Valeriote FA, Gerwick L, Gerwick WH. PMID: 34269583.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    42. Cyanobacteria-shrimp colonies in the Mariana Islands. Aquat Ecol. 2021 Jun; 55(2):453-465. Leber CA, Reyes AJ, Biggs JS, Gerwick WH. PMID: 34177357; PMCID: PMC8223766.
      View in: PubMed   Mentions:
    43. Total Synthesis of Laucysteinamide A, a Monomeric Congener of Somocystinamide A. J Nat Prod. 2021 03 26; 84(3):865-870. Taylor KS, Zhang C, Glukhov E, Gerwick WH, Suyama TL. PMID: 33635664.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    44. Kalkitoxin Reduces Osteoclast Formation and Resorption and Protects against Inflammatory Bone Loss. Int J Mol Sci. 2021 Feb 25; 22(5). Li L, Yang M, Shrestha SK, Kim H, Gerwick WH, Soh Y. PMID: 33669069; PMCID: PMC7956546.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    45. A Multi-Omics Characterization of the Natural Product Potential of Tropical Filamentous Marine Cyanobacteria. Mar Drugs. 2021 Jan 06; 19(1). Leão T, Wang M, Moss N, da Silva R, Sanders J, Nurk S, Gurevich A, Humphrey G, Reher R, Zhu Q, Belda-Ferre P, Glukhov E, Whitner S, Alexander KL, Rex R, Pevzner P, Dorrestein PC, Knight R, Bandeira N, Gerwick WH, Gerwick L. PMID: 33418911; PMCID: PMC7825088.
      View in: PubMed   Mentions: 11     Fields:    Translation:Cells
    46. Potent in vitro anti-SARS-CoV-2 activity by gallinamide A and analogues via inhibition of cathepsin L. bioRxiv. 2020 Dec 24. Ashhurst AS, Tang AH, Fajtová P, Yoon M, Aggarwal A, Stoye A, Larance M, Beretta L, Drelich A, Skinner D, Li L, Meek TD, McKerrow JH, Hook V, Tseng CK, Turville S, Gerwick WH, O'Donoghue AJ, Payne RJ. PMID: 33398273; PMCID: PMC7781308.
      View in: PubMed   Mentions: 3  
    47. Natural Products with Potential to Treat RNA Virus Pathogens Including SARS-CoV-2. J Nat Prod. 2021 01 22; 84(1):161-182. Christy MP, Uekusa Y, Gerwick L, Gerwick WH. PMID: 33352046; PMCID: PMC7771248.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    48. Systematic classification of unknown metabolites using high-resolution fragmentation mass spectra. Nat Biotechnol. 2021 04; 39(4):462-471. Dührkop K, Nothias LF, Fleischauer M, Reher R, Ludwig M, Hoffmann MA, Petras D, Gerwick WH, Rousu J, Dorrestein PC, Böcker S. PMID: 33230292.
      View in: PubMed   Mentions: 147     Fields:    Translation:Animals
    49. Heterologous Expression of Cryptomaldamide in a Cyanobacterial Host. ACS Synth Biol. 2020 12 18; 9(12):3364-3376. Taton A, Ecker A, Diaz B, Moss NA, Anderson B, Reher R, Leão TF, Simkovsky R, Dorrestein PC, Gerwick L, Gerwick WH, Golden JW. PMID: 33180461; PMCID: PMC8514081.
      View in: PubMed   Mentions: 16     Fields:    Translation:Cells
    50. Applying a Chemogeographic Strategy for Natural Product Discovery from the Marine Cyanobacterium Moorena bouillonii. Mar Drugs. 2020 Oct 14; 18(10). Leber CA, Naman CB, Keller L, Almaliti J, Caro-Diaz EJE, Glukhov E, Joseph V, Sajeevan TP, Reyes AJ, Biggs JS, Li T, Yuan Y, He S, Yan X, Gerwick WH. PMID: 33066480; PMCID: PMC7602127.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    51. The Chemistry, Biochemistry and Pharmacology of Marine Natural Products from Leptolyngbya, a Chemically Endowed Genus of Cyanobacteria. Mar Drugs. 2020 Oct 06; 18(10). Li Y, Naman CB, Alexander KL, Guan H, Gerwick WH. PMID: 33036172; PMCID: PMC7600079.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    52. Epicortical Brevetoxin Treatment Promotes Neural Repair and Functional Recovery after Ischemic Stroke. Mar Drugs. 2020 Jul 21; 18(7). Sequeira E, Pierce ML, Akasheh D, Sellers S, Gerwick WH, Baden DG, Murray TF. PMID: 32708077; PMCID: PMC7404386.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    53. Correction to "Highly Convergent Total Synthesis and Assignment of Absolute Configuration of Majusculamide D, a Potent and Selective Cytotoxic Metabolite from Moorea sp." Org Lett. 2020 Aug 07; 22(15):6220. Caro-Diaz EJE, Valeriote FA, Gerwick WH. PMID: 32680425.
      View in: PubMed   Mentions:    Fields:    
    54. Synergism of anisotropic and computational NMR methods reveals the likely configuration of phormidolide A. Chem Commun (Camb). 2020 Jul 09; 56(55):7565-7568. Ndukwe IE, Wang X, Lam NYS, Ermanis K, Alexander KL, Bertin MJ, Martin GE, Muir G, Paterson I, Britton R, Goodman JM, Helfrich EJN, Piel J, Gerwick WH, Williamson RT. PMID: 32520016; PMCID: PMC7436192.
      View in: PubMed   Mentions: 6     Fields:    Translation:Cells
    55. An anti-inflammatory isoflavone from soybean inoculated with a marine fungus Aspergillus terreus C23-3. Biosci Biotechnol Biochem. 2020 Aug; 84(8):1546-1553. Yang JM, Liu YY, Yang WC, Ma XX, Nie YY, Glukhov E, Gerwick L, Gerwick WH, Lei XL, Zhang Y. PMID: 32434451.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    56. Commensal Oral Rothia mucilaginosa Produces Enterobactin, a Metal-Chelating Siderophore. mSystems. 2020 Apr 28; 5(2). Uranga CC, Arroyo P, Duggan BM, Gerwick WH, Edlund A. PMID: 32345739; PMCID: PMC7190385.
      View in: PubMed   Mentions: 24     Fields:    
    57. Palstimolide A: A Complex Polyhydroxy Macrolide with Antiparasitic Activity. Molecules. 2020 Mar 31; 25(7). Keller L, Siqueira-Neto JL, Souza JM, Eribez K, LaMonte GM, Smith JE, Gerwick WH. PMID: 32244512; PMCID: PMC7180531.
      View in: PubMed   Mentions: 9     Fields:    Translation:Cells
    58. Author Correction: Small Molecule Accurate Recognition Technology (SMART) to Enhance Natural Products Research. Sci Rep. 2020 Mar 10; 10(1):4724. Zhang C, Idelbayev Y, Roberts N, Tao Y, Nannapaneni Y, Duggan BM, Min J, Lin EC, Gerwick EC, Cottrell GW, Gerwick WH. PMID: 32152329; PMCID: PMC7062778.
      View in: PubMed   Mentions:    Fields:    
    59. A Convolutional Neural Network-Based Approach for the Rapid Annotation of Molecularly Diverse Natural Products. J Am Chem Soc. 2020 03 04; 142(9):4114-4120. Reher R, Kim HW, Zhang C, Mao HH, Wang M, Nothias LF, Caraballo-Rodriguez AM, Glukhov E, Teke B, Leao T, Alexander KL, Duggan BM, Van Everbroeck EL, Dorrestein PC, Cottrell GW, Gerwick WH. PMID: 32045230; PMCID: PMC7210566.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansCells
    60. Tutuilamides A-C: Vinyl-Chloride-Containing Cyclodepsipeptides from Marine Cyanobacteria with Potent Elastase Inhibitory Properties. ACS Chem Biol. 2020 03 20; 15(3):751-757. Keller L, Canuto KM, Liu C, Suzuki BM, Almaliti J, Sikandar A, Naman CB, Glukhov E, Luo D, Duggan BM, Luesch H, Koehnke J, O'Donoghue AJ, Gerwick WH. PMID: 31935054; PMCID: PMC7480958.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    61. Pagoamide A, a Cyclic Depsipeptide Isolated from a Cultured Marine Chlorophyte, Derbesia sp., Using MS/MS-Based Molecular Networking. J Nat Prod. 2020 03 27; 83(3):617-625. Li Y, Yu HB, Zhang Y, Leao T, Glukhov E, Pierce ML, Zhang C, Kim H, Mao HH, Fang F, Cottrell GW, Murray TF, Gerwick L, Guan H, Gerwick WH. PMID: 31916778; PMCID: PMC7210564.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    62. Repurposing the GNAT Fold in the Initiation of Polyketide Biosynthesis. Structure. 2020 01 07; 28(1):63-74.e4. Skiba MA, Tran CL, Dan Q, Sikkema AP, Klaver Z, Gerwick WH, Sherman DH, Smith JL. PMID: 31785925; PMCID: PMC6949403.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    63. 20S Proteasome as a Drug Target in Trichomonas vaginalis. Antimicrob Agents Chemother. 2019 11; 63(11). O'Donoghue AJ, Bibo-Verdugo B, Miyamoto Y, Wang SC, Yang JZ, Zuill DE, Matsuka S, Jiang Z, Almaliti J, Caffrey CR, Gerwick WH, Eckmann L. PMID: 31451503; PMCID: PMC6811414.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    64. MetaMiner: A Scalable Peptidogenomics Approach for Discovery of Ribosomal Peptide Natural Products with Blind Modifications from Microbial Communities. Cell Syst. 2019 12 18; 9(6):600-608.e4. Cao L, Gurevich A, Alexander KL, Naman CB, Leão T, Glukhov E, Luzzatto-Knaan T, Vargas F, Quinn R, Bouslimani A, Nothias LF, Singh NK, Sanders JG, Benitez RAS, Thompson LR, Hamid MN, Morton JT, Mikheenko A, Shlemov A, Korobeynikov A, Friedberg I, Knight R, Venkateswaran K, Gerwick WH, Gerwick L, Dorrestein PC, Pevzner PA, Mohimani H. PMID: 31629686; PMCID: PMC6952069.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansCells
    65. Design of Gallinamide A Analogs as Potent Inhibitors of the Cysteine Proteases Human Cathepsin L and Trypanosoma cruzi Cruzain. J Med Chem. 2019 10 24; 62(20):9026-9044. Boudreau PD, Miller BW, McCall LI, Almaliti J, Reher R, Hirata K, Le T, Siqueira-Neto JL, Hook V, Gerwick WH. PMID: 31539239; PMCID: PMC7240701.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimals
    66. Cytotoxic Microcolin Lipopeptides from the Marine Cyanobacterium Moorea producens. J Nat Prod. 2019 09 27; 82(9):2608-2619. Yu HB, Glukhov E, Li Y, Iwasaki A, Gerwick L, Dorrestein PC, Jiao BH, Gerwick WH. PMID: 31468974.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    67. The Proteasome as a Drug Target in the Metazoan Pathogen, Schistosoma mansoni. ACS Infect Dis. 2019 10 11; 5(10):1802-1812. Bibo-Verdugo B, Wang SC, Almaliti J, Ta AP, Jiang Z, Wong DA, Lietz CB, Suzuki BM, El-Sakkary N, Hook V, Salvesen GS, Gerwick WH, Caffrey CR, O'Donoghue AJ. PMID: 31355632; PMCID: PMC7283364.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    68. Nature's Combinatorial Biosynthesis Produces Vatiamides A-F. Angew Chem Int Ed Engl. 2019 07 01; 58(27):9027-9031. Moss NA, Seiler G, Leão TF, Castro-Falcón G, Gerwick L, Hughes CC, Gerwick WH. PMID: 31071229; PMCID: PMC6626303.
      View in: PubMed   Mentions: 20     Fields:    Translation:Cells
    69. Analysis of the antiparasitic and anticancer activity of the coconut palm (Cocos nucifera L. ARECACEAE) from the natural reserve of Punta Patiño, Darién. PLoS One. 2019; 14(4):e0214193. Tayler NM, Boya CA, Herrera L, Moy J, Ng M, Pineda L, Almanza A, Rosero S, Coronado LM, Correa R, Santamaría R, Caballero Z, Durant-Archibold AA, Tidgewell KJ, Balunas MJ, Gerwick WH, Spadafora A, Gutiérrez M, Spadafora C. PMID: 30939131; PMCID: PMC6445518.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    70. Highly Convergent Total Synthesis and Assignment of Absolute Configuration of Majusculamide D, a Potent and Selective Cytotoxic Metabolite from Moorea sp. Org Lett. 2019 02 01; 21(3):793-796. Caro-Diaz EJE, Valeriote FA, Gerwick WH. PMID: 30673235.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    71. 1-Octen-3-ol, a self-stimulating oxylipin messenger, can prime and induce defense of marine alga. BMC Plant Biol. 2019 Jan 22; 19(1):37. Chen H, Yang R, Chen J, Luo Q, Cui X, Yan X, Gerwick WH. PMID: 30669983; PMCID: PMC6341616.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    72. Integrated Genomic and Metabolomic Approach to the Discovery of Potential Anti-Quorum Sensing Natural Products from Microbes Associated with Marine Samples from Singapore. Mar Drugs. 2019 Jan 21; 17(1). Ong JFM, Goh HC, Lim SC, Pang LM, Chin JSF, Tan KS, Liang ZX, Yang L, Glukhov E, Gerwick WH, Tan LT. PMID: 30669697; PMCID: PMC6356914.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    73. Marine natural products as potential anti-tubercular agents. Eur J Med Chem. 2019 Mar 01; 165:273-292. Hou XM, Wang CY, Gerwick WH, Shao CL. PMID: 30685527.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimals
    74. Dragocins A-D, Structurally Intriguing Cytotoxic Metabolites from a Panamanian Marine Cyanobacterium. Org Lett. 2019 01 04; 21(1):266-270. Choi H, Engene N, Byrum T, Hwang S, Oh DC, Gerwick WH. PMID: 30566359.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    75. MS/MS-Based Molecular Networking Approach for the Detection of Aplysiatoxin-Related Compounds in Environmental Marine Cyanobacteria. Mar Drugs. 2018 Dec 13; 16(12). Ding CYG, Pang LM, Liang ZX, Goh KKK, Glukhov E, Gerwick WH, Tan LT. PMID: 30551660; PMCID: PMC6315786.
      View in: PubMed   Mentions: 10     Fields:    Translation:Cells
    76. Ketoreductase Domain Dysfunction Expands Chemodiversity: Malyngamide Biosynthesis in the Cyanobacterium Okeania hirsuta. ACS Chem Biol. 2018 12 21; 13(12):3385-3395. Moss NA, Leão T, Rankin MR, McCullough TM, Qu P, Korobeynikov A, Smith JL, Gerwick L, Gerwick WH. PMID: 30444349; PMCID: PMC6470004.
      View in: PubMed   Mentions: 13     Fields:    Translation:Cells
    77. Structural Basis of Polyketide Synthase O-Methylation. ACS Chem Biol. 2018 12 21; 13(12):3221-3228. Skiba MA, Bivins MM, Schultz JR, Bernard SM, Fiers WD, Dan Q, Kulkarni S, Wipf P, Gerwick WH, Sherman DH, Aldrich CC, Smith JL. PMID: 30489068; PMCID: PMC6470024.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    78. Correction: The value of universally available raw NMR data for transparency, reproducibility, and integrity in natural product research. Nat Prod Rep. 2019 01 01; 36(1):248-249. McAlpine JB, Chen SN, Kutateladze A, MacMillan JB, Appendino G, Barison A, Beniddir MA, Biavatti MW, Bluml S, Boufridi A, Butler MS, Capon RJ, Choi YH, Coppage D, Crews P, Crimmins MT, Csete M, Dewapriya P, Egan JM, Garson MJ, Genta-Jouve G, Gerwick WH, Gross H, Harper MK, Hermanto P, Hook JM, Hunter L, Jeannerat D, Ji NY, Johnson TA, Kingston DGI, Koshino H, Lee HW, Lewin G, Li J, Linington RG, Liu M, McPhail KL, Molinski TF, Moore BS, Nam JW, Neupane RP, Niemitz M, Nuzillard JM, Oberlies NH, Ocampos FMM, Pan G, Quinn RJ, Reddy DS, Renault JH, Rivera-Chávez J, Robien W, Saunders CM, Schmidt TJ, Seger C, Shen B, Steinbeck C, Stuppner H, Sturm S, Taglialatela-Scafati O, Tantillo DJ, Verpoorte R, Wang BG, Williams CM, Williams PG, Wist J, Yue JM, Zhang C, Xu Z, Simmler C, Lankin DC, Bisson J, Pauli GF. PMID: 30468235; PMCID: PMC6474672.
      View in: PubMed   Mentions: 2     Fields:    
    79. Exploration of the carmaphycins as payloads in antibody drug conjugate anticancer agents. Eur J Med Chem. 2019 Jan 01; 161:416-432. Almaliti J, Miller B, Pietraszkiewicz H, Glukhov E, Naman CB, Kline T, Hanson J, Li X, Zhou S, Valeriote FA, Gerwick WH. PMID: 30384045; PMCID: PMC6248884.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    80. The Metabolome of a Cyanobacterial Bloom Visualized by MS/MS-Based Molecular Networking Reveals New Neurotoxic Smenamide Analogs (C, D, and E). Front Chem. 2018; 6:316. Via CW, Glukhov E, Costa S, Zimba PV, Moeller PDR, Gerwick WH, Bertin MJ. PMID: 30094232; PMCID: PMC6071517.
      View in: PubMed   Mentions: 11  
    81. The value of universally available raw NMR data for transparency, reproducibility, and integrity in natural product research. Nat Prod Rep. 2019 01 01; 36(1):35-107. McAlpine JB, Chen SN, Kutateladze A, MacMillan JB, Appendino G, Barison A, Beniddir MA, Biavatti MW, Bluml S, Boufridi A, Butler MS, Capon RJ, Choi YH, Coppage D, Crews P, Crimmins MT, Csete M, Dewapriya P, Egan JM, Garson MJ, Genta-Jouve G, Gerwick WH, Gross H, Harper MK, Hermanto P, Hook JM, Hunter L, Jeannerat D, Ji NY, Johnson TA, Kingston DGI, Koshino H, Lee HW, Lewin G, Li J, Linington RG, Liu M, McPhail KL, Molinski TF, Moore BS, Nam JW, Neupane RP, Niemitz M, Nuzillard JM, Oberlies NH, Ocampos FMM, Pan G, Quinn RJ, Reddy DS, Renault JH, Rivera-Chávez J, Robien W, Saunders CM, Schmidt TJ, Seger C, Shen B, Steinbeck C, Stuppner H, Sturm S, Taglialatela-Scafati O, Tantillo DJ, Verpoorte R, Wang BG, Williams CM, Williams PG, Wist J, Yue JM, Zhang C, Xu Z, Simmler C, Lankin DC, Bisson J, Pauli GF. PMID: 30003207; PMCID: PMC6350634.
      View in: PubMed   Mentions: 38     Fields:    Translation:Cells
    82. Identification of a 3-Alkylpyridinium Compound from the Red Sea Sponge Amphimedon chloros with In Vitro Inhibitory Activity against the West Nile Virus NS3 Protease. Molecules. 2018 06 18; 23(6). O'Rourke A, Kremb S, Duggan BM, Sioud S, Kharbatia N, Raji M, Emwas AH, Gerwick WH, Voolstra CR. PMID: 29912151; PMCID: PMC6099703.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    83. Corrigendum to: "Alkaloids from Corydalis decumbens suppress neuronal excitability in primary cultures of mouse neocortical neurons" [Phytochemistry (2018) 150 85-92]. Phytochemistry. 2018 10; 154:106-107. Huang Q, Chen J, Zhang W, Zhou B, Zhang C, Gerwick WH, Cao Z. PMID: 29907440.
      View in: PubMed   Mentions:    Fields:    
    84. Characterization of Rhamnolipids Produced by an Arctic Marine Bacterium from the Pseudomonas fluorescence Group. Mar Drugs. 2018 May 14; 16(5). Kristoffersen V, Rämä T, Isaksson J, Andersen JH, Gerwick WH, Hansen E. PMID: 29758007; PMCID: PMC5983294.
      View in: PubMed   Mentions: 17     Fields:    Translation:Cells
    85. Biosynthesis of t-Butyl in Apratoxin A: Functional Analysis and Architecture of a PKS Loading Module. ACS Chem Biol. 2018 06 15; 13(6):1640-1650. Skiba MA, Sikkema AP, Moss NA, Lowell AN, Su M, Sturgis RM, Gerwick L, Gerwick WH, Sherman DH, Smith JL. PMID: 29701944; PMCID: PMC6003868.
      View in: PubMed   Mentions: 12     Fields:    Translation:Cells
    86. Collection, Culturing, and Genome Analyses of Tropical Marine Filamentous Benthic Cyanobacteria. Methods Enzymol. 2018; 604:3-43. Moss NA, Leao T, Glukhov E, Gerwick L, Gerwick WH. PMID: 29779657.
      View in: PubMed   Mentions: 8     Fields:    Translation:CellsPHPublic Health
    87. Eckmaxol, a Phlorotannin Extracted from Ecklonia maxima, Produces Anti-β-amyloid Oligomer Neuroprotective Effects Possibly via Directly Acting on Glycogen Synthase Kinase 3β. ACS Chem Neurosci. 2018 06 20; 9(6):1349-1356. Wang J, Zheng J, Huang C, Zhao J, Lin J, Zhou X, Naman CB, Wang N, Gerwick WH, Wang Q, Yan X, Cui W, He S. PMID: 29608860.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCells
    88. Alkaloids from Corydalis decumbens suppress neuronal excitability in primary cultures of mouse neocortical neurons. Phytochemistry. 2018 Jun; 150:85-92. Huang Q, Chen J, Zhang W, Zhou B, Zhang C, Gerwick WH, Cao Z. PMID: 29571149.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    89. Samholides, Swinholide-Related Metabolites from a Marine Cyanobacterium cf. Phormidium sp. J Org Chem. 2018 03 16; 83(6):3034-3046. Tao Y, Li P, Zhang D, Glukhov E, Gerwick L, Zhang C, Murray TF, Gerwick WH. PMID: 29457979; PMCID: PMC5859247.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    90. Bastimolide B, an Antimalarial 24-Membered Marine Macrolide Possessing a tert-Butyl Group. J Nat Prod. 2018 01 26; 81(1):211-215. Shao CL, Mou XF, Cao F, Spadafora C, Glukhov E, Gerwick L, Wang CY, Gerwick WH. PMID: 29327931.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    91. Marine Natural Product Honaucin A Attenuates Inflammation by Activating the Nrf2-ARE Pathway. J Nat Prod. 2018 03 23; 81(3):506-514. Mascuch SJ, Boudreau PD, Carland TM, Pierce NT, Olson J, Hensler ME, Choi H, Campanale J, Hamdoun A, Nizet V, Gerwick WH, Gaasterland T, Gerwick L. PMID: 29215273; PMCID: PMC6553616.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    92. A Mononuclear Iron-Dependent Methyltransferase Catalyzes Initial Steps in Assembly of the Apratoxin A Polyketide Starter Unit. ACS Chem Biol. 2017 12 15; 12(12):3039-3048. Skiba MA, Sikkema AP, Moss NA, Tran CL, Sturgis RM, Gerwick L, Gerwick WH, Sherman DH, Smith JL. PMID: 29096064; PMCID: PMC5784268.
      View in: PubMed   Mentions: 12     Fields:    Translation:Cells
    93. Small Molecule Accurate Recognition Technology (SMART) to Enhance Natural Products Research. Sci Rep. 2017 10 27; 7(1):14243. Zhang C, Idelbayev Y, Roberts N, Tao Y, Nannapaneni Y, Duggan BM, Min J, Lin EC, Gerwick EC, Cottrell GW, Gerwick WH. PMID: 29079836; PMCID: PMC5660213.
      View in: PubMed   Mentions: 33     Fields:    Translation:Cells
    94. The Face of a Molecule. J Nat Prod. 2017 09 22; 80(9):2583-2588. Gerwick WH. PMID: 28885833.
      View in: PubMed   Mentions: 10     Fields:    Translation:Cells
    95. 5-Hydroxycyclopenicillone, a New β-Amyloid Fibrillization Inhibitor from a Sponge-Derived Fungus Trichoderma sp. HPQJ-34. Mar Drugs. 2017 Aug 19; 15(8). Fang F, Zhao J, Ding L, Huang C, Naman CB, He S, Wu B, Zhu P, Luo Q, Gerwick WH, Yan X, Wang Q, Zhang Z, Cui W. PMID: 28825620; PMCID: PMC5577614.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    96. Fucoxanthin, a Marine Carotenoid, Attenuates β-Amyloid Oligomer-Induced Neurotoxicity Possibly via Regulating the PI3K/Akt and the ERK Pathways in SH-SY5Y Cells. Oxid Med Cell Longev. 2017; 2017:6792543. Lin J, Yu J, Zhao J, Zhang K, Zheng J, Wang J, Huang C, Zhang J, Yan X, Gerwick WH, Wang Q, Cui W, He S. PMID: 28928905; PMCID: PMC5591933.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansCells
    97. Discovery and Synthesis of Caracolamide A, an Ion Channel Modulating Dichlorovinylidene Containing Phenethylamide from a Panamanian Marine Cyanobacterium cf. Symploca Species. J Nat Prod. 2017 08 25; 80(8):2328-2334. Naman CB, Almaliti J, Armstrong L, Caro-Díaz EJ, Pierce ML, Glukhov E, Fenner A, Spadafora C, Debonsi HM, Dorrestein PC, Murray TF, Gerwick WH. PMID: 28783331.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    98. Development of a Potent Inhibitor of the Plasmodium Proteasome with Reduced Mammalian Toxicity. J Med Chem. 2017 08 10; 60(15):6721-6732. LaMonte GM, Almaliti J, Bibo-Verdugo B, Keller L, Zou BY, Yang J, Antonova-Koch Y, Orjuela-Sanchez P, Boyle CA, Vigil E, Wang L, Goldgof GM, Gerwick L, O'Donoghue AJ, Winzeler EA, Gerwick WH, Ottilie S. PMID: 28696697; PMCID: PMC5554889.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansAnimalsCells
    99. Reply to Skinnider and Magarvey: Rates of novel natural product discovery remain high. Proc Natl Acad Sci U S A. 2017 08 01; 114(31):E6273. Pye CR, Bertin MJ, Lokey RS, Gerwick WH, Linington RG. PMID: 28710331; PMCID: PMC5547657.
      View in: PubMed   Mentions: 1     Fields:    
    100. Dudawalamides A-D, Antiparasitic Cyclic Depsipeptides from the Marine Cyanobacterium Moorea producens. J Nat Prod. 2017 06 23; 80(6):1827-1836. Almaliti J, Malloy KL, Glukhov E, Spadafora C, Gutiérrez M, Gerwick WH. PMID: 28535042.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    101. Digitizing mass spectrometry data to explore the chemical diversity and distribution of marine cyanobacteria and algae. Elife. 2017 05 11; 6. Luzzatto-Knaan T, Garg N, Wang M, Glukhov E, Peng Y, Ackermann G, Amir A, Duggan BM, Ryazanov S, Gerwick L, Knight R, Alexandrov T, Bandeira N, Gerwick WH, Dorrestein PC. PMID: 28492366; PMCID: PMC5441867.
      View in: PubMed   Mentions: 19     Fields:    Translation:Cells
    102. Retrospective analysis of natural products provides insights for future discovery trends. Proc Natl Acad Sci U S A. 2017 05 30; 114(22):5601-5606. Pye CR, Bertin MJ, Lokey RS, Gerwick WH, Linington RG. PMID: 28461474; PMCID: PMC5465889.
      View in: PubMed   Mentions: 154     Fields:    Translation:Humans
    103. A Maldiisotopic Approach to Discover Natural Products: Cryptomaldamide, a Hybrid Tripeptide from the Marine Cyanobacterium Moorea producens. J Nat Prod. 2017 05 26; 80(5):1514-1521. Kinnel RB, Esquenazi E, Leao T, Moss N, Mevers E, Pereira AR, Monroe EA, Korobeynikov A, Murray TF, Sherman D, Gerwick L, Dorrestein PC, Gerwick WH. PMID: 28448144; PMCID: PMC5748289.
      View in: PubMed   Mentions: 14     Fields:    Translation:Cells
    104. Laucysteinamide A, a Hybrid PKS/NRPS Metabolite from a Saipan Cyanobacterium, cf. Caldora penicillata. Mar Drugs. 2017 Apr 14; 15(4). Zhang C, Naman CB, Engene N, Gerwick WH. PMID: 28420100; PMCID: PMC5408267.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    105. Streptomyces artemisiae MCCB 248 isolated from Arctic fjord sediments has unique PKS and NRPS biosynthetic genes and produces potential new anticancer natural products. 3 Biotech. 2017 May; 7(1):32. Dhaneesha M, Benjamin Naman C, Krishnan KP, Sinha RK, Jayesh P, Joseph V, Bright Singh IS, Gerwick WH, Sajeevan TP. PMID: 28401470; PMCID: PMC5388659.
      View in: PubMed   Mentions: 8  
    106. Comparative genomics uncovers the prolific and distinctive metabolic potential of the cyanobacterial genus Moorea. Proc Natl Acad Sci U S A. 2017 03 21; 114(12):3198-3203. Leao T, Castelão G, Korobeynikov A, Monroe EA, Podell S, Glukhov E, Allen EE, Gerwick WH, Gerwick L. PMID: 28265051; PMCID: PMC5373345.
      View in: PubMed   Mentions: 35     Fields:    Translation:Cells
    107. Integrating Molecular Networking and Biological Assays To Target the Isolation of a Cytotoxic Cyclic Octapeptide, Samoamide A, from an American Samoan Marine Cyanobacterium. J Nat Prod. 2017 03 24; 80(3):625-633. Naman CB, Rattan R, Nikoulina SE, Lee J, Miller BW, Moss NA, Armstrong L, Boudreau PD, Debonsi HM, Valeriote FA, Dorrestein PC, Gerwick WH. PMID: 28055219; PMCID: PMC5758054.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    108. Corrigendum: Biosynthesis-Assisted Structural Elucidation of the Bartolosides, Chlorinated Aromatic Glycolipids from Cyanobacteria. Angew Chem Int Ed Engl. 2016 11 21; 55(48):14895. Leão PN, Nakamura H, Costa M, Pereira AR, Martins R, Vasconcelos V, Gerwick WH, Balskus EP. PMID: 27860179; PMCID: PMC6547823.
      View in: PubMed   Mentions:    Fields:    
    109. Domain Organization and Active Site Architecture of a Polyketide Synthase C-methyltransferase. ACS Chem Biol. 2016 12 16; 11(12):3319-3327. Skiba MA, Sikkema AP, Fiers WD, Gerwick WH, Sherman DH, Aldrich CC, Smith JL. PMID: 27723289; PMCID: PMC5224524.
      View in: PubMed   Mentions: 24     Fields:    Translation:Cells
    110. Bissubvilides A and B, Cembrane-Capnosane Heterodimers from the Soft Coral Sarcophyton subviride. J Nat Prod. 2016 10 28; 79(10):2552-2558. Sun P, Yu Q, Li J, Riccio R, Lauro G, Bifulco G, Kurtán T, Mándi A, Tang H, Li TJ, Zhuang CL, Gerwick WH, Zhang W. PMID: 27704808.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    111. Bioactive new metabolites from the green alga Udotea orientalis growing on the Gorgonian coral Pseudopterogorgia rigida. Nat Prod Res. 2017 Jun; 31(11):1245-1250. Sabry OM, Goeger DE, Gerwick WH. PMID: 27653761; PMCID: PMC5553317.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    112. Cytotoxic halogenated monoterpenes from Plocamium cartilagineum. Nat Prod Res. 2017 Feb; 31(3):261-267. Sabry OM, Goeger DE, Valeriote FA, Gerwick WH. PMID: 27627578; PMCID: PMC5748142.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    113. A novel uncultured heterotrophic bacterial associate of the cyanobacterium Moorea producens JHB. BMC Microbiol. 2016 08 30; 16(1):198. Cummings ME, Barbé D, Leao TF, Korobeynikov A, Engene N, Glukhov E, Gerwick WH, Gerwick L. PMID: 27577966; PMCID: PMC5006271.
      View in: PubMed   Mentions: 7     Fields:    Translation:Cells
    114. Anatomy of the β-branching enzyme of polyketide biosynthesis and its interaction with an acyl-ACP substrate. Proc Natl Acad Sci U S A. 2016 09 13; 113(37):10316-21. Maloney FP, Gerwick L, Gerwick WH, Sherman DH, Smith JL. PMID: 27573844; PMCID: PMC5027445.
      View in: PubMed   Mentions: 12     Fields:    Translation:Cells
    115. Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking. Nat Biotechnol. 2016 08 09; 34(8):828-837. Wang M, Carver JJ, Phelan VV, Sanchez LM, Garg N, Peng Y, Nguyen DD, Watrous J, Kapono CA, Luzzatto-Knaan T, Porto C, Bouslimani A, Melnik AV, Meehan MJ, Liu WT, Crüsemann M, Boudreau PD, Esquenazi E, Sandoval-Calderón M, Kersten RD, Pace LA, Quinn RA, Duncan KR, Hsu CC, Floros DJ, Gavilan RG, Kleigrewe K, Northen T, Dutton RJ, Parrot D, Carlson EE, Aigle B, Michelsen CF, Jelsbak L, Sohlenkamp C, Pevzner P, Edlund A, McLean J, Piel J, Murphy BT, Gerwick L, Liaw CC, Yang YL, Humpf HU, Maansson M, Keyzers RA, Sims AC, Johnson AR, Sidebottom AM, Sedio BE, Klitgaard A, Larson CB, P CAB, Torres-Mendoza D, Gonzalez DJ, Silva DB, Marques LM, Demarque DP, Pociute E, O'Neill EC, Briand E, Helfrich EJN, Granatosky EA, Glukhov E, Ryffel F, Houson H, Mohimani H, Kharbush JJ, Zeng Y, Vorholt JA, Kurita KL, Charusanti P, McPhail KL, Nielsen KF, Vuong L, Elfeki M, Traxler MF, Engene N, Koyama N, Vining OB, Baric R, Silva RR, Mascuch SJ, Tomasi S, Jenkins S, Macherla V, Hoffman T, Agarwal V, Williams PG, Dai J, Neupane R, Gurr J, Rodríguez AMC, Lamsa A, Zhang C, Dorrestein K, Duggan BM, Almaliti J, Allard PM, Phapale P, Nothias LF, Alexandrov T, Litaudon M, Wolfender JL, Kyle JE, Metz TO, Peryea T, Nguyen DT, VanLeer D, Shinn P, Jadhav A, Müller R, Waters KM, Shi W, Liu X, Zhang L, Knight R, Jensen PR, Palsson BO, Pogliano K, Linington RG, Gutiérrez M, Lopes NP, Gerwick WH, Moore BS, Dorrestein PC, Bandeira N. PMID: 27504778; PMCID: PMC5321674.
      View in: PubMed   Mentions: 1343     Fields:    
    116. Biologically active new metabolites from a Florida collection of Moorea producens. Nat Prod Res. 2017 Mar; 31(5):555-561. Sabry OM, Goeger DE, Gerwick WH. PMID: 27426414; PMCID: PMC5605289.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    117. Uprolides N, O and P from the Panamanian Octocoral Eunicea succinea. Molecules. 2016 Jun 22; 21(6). Torres-Mendoza D, González Y, Gómez-Reyes JF, Guzmán HM, López-Perez JL, Gerwick WH, Fernandez PL, Gutiérrez M. PMID: 27338338; PMCID: PMC6273691.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    118. Assessment of Anabaena sp. Strain PCC 7120 as a Heterologous Expression Host for Cyanobacterial Natural Products: Production of Lyngbyatoxin A. ACS Synth Biol. 2016 09 16; 5(9):978-88. Videau P, Wells KN, Singh AJ, Gerwick WH, Philmus B. PMID: 27176641.
      View in: PubMed   Mentions: 24     Fields:    Translation:Cells
    119. Small Molecule DFPM Derivative-Activated Plant Resistance Protein Signaling in Roots Is Unaffected by EDS1 Subcellular Targeting Signal and Chemical Genetic Isolation of victr R-Protein Mutants. PLoS One. 2016; 11(5):e0155937. Kunz HH, Park J, Mevers E, García AV, Highhouse S, Gerwick WH, Parker JE, Schroeder JI. PMID: 27219122; PMCID: PMC4878808.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    120. Apratoxin Kills Cells by Direct Blockade of the Sec61 Protein Translocation Channel. Cell Chem Biol. 2016 05 19; 23(5):561-566. Paatero AO, Kellosalo J, Dunyak BM, Almaliti J, Gestwicki JE, Gerwick WH, Taunton J, Paavilainen VO. PMID: 27203376.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansCells
    121. Apratoxin A Shows Novel Pancreas-Targeting Activity through the Binding of Sec 61. Mol Cancer Ther. 2016 06; 15(6):1208-16. Huang KC, Chen Z, Jiang Y, Akare S, Kolber-Simonds D, Condon K, Agoulnik S, Tendyke K, Shen Y, Wu KM, Mathieu S, Choi HW, Zhu X, Shimizu H, Kotake Y, Gerwick WH, Uenaka T, Woodall-Jappe M, Nomoto K. PMID: 27196783.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    122. Role of bacteria in the production and degradation of Microcystis cyanopeptides. Microbiologyopen. 2016 06; 5(3):469-78. Briand E, Humbert JF, Tambosco K, Bormans M, Gerwick WH. PMID: 26918405; PMCID: PMC4905998.
      View in: PubMed   Mentions: 16     Fields:    Translation:Cells
    123. Alkaloids from the Sponge Stylissa carteri Present Prospective Scaffolds for the Inhibition of Human Immunodeficiency Virus 1 (HIV-1). Mar Drugs. 2016 Feb 04; 14(2). O'Rourke A, Kremb S, Bader TM, Helfer M, Schmitt-Kopplin P, Gerwick WH, Brack-Werner R, Voolstra CR. PMID: 26861355; PMCID: PMC4771981.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    124. Unique marine derived cyanobacterial biosynthetic genes for chemical diversity. Nat Prod Rep. 2016 Feb; 33(2):348-64. Kleigrewe K, Gerwick L, Sherman DH, Gerwick WH. PMID: 26758451.
      View in: PubMed   Mentions: 26     Fields:    Translation:Cells
    125. Medusamide A, a Panamanian Cyanobacterial Depsipeptide with Multiple β-Amino Acids. Org Lett. 2016 Feb 05; 18(3):352-5. Fenner AM, Engene N, Spadafora C, Gerwick WH, Balunas MJ. PMID: 26784681.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    126. The Phormidolide Biosynthetic Gene Cluster: A trans-AT PKS Pathway Encoding a Toxic Macrocyclic Polyketide. Chembiochem. 2016 Jan; 17(2):164-73. Bertin MJ, Vulpanovici A, Monroe EA, Korobeynikov A, Sherman DH, Gerwick L, Gerwick WH. PMID: 26769357; PMCID: PMC4878910.
      View in: PubMed   Mentions: 13     Fields:    Translation:Cells
    127. Kalkipyrone B, a marine cyanobacterial γ-pyrone possessing cytotoxic and anti-fungal activities. Phytochemistry. 2016 Feb; 122:113-118. Bertin MJ, Demirkiran O, Navarro G, Moss NA, Lee J, Goldgof GM, Vigil E, Winzeler EA, Valeriote FA, Gerwick WH. PMID: 26632528; PMCID: PMC4724546.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    128. Combined LC-MS/MS and Molecular Networking Approach Reveals New Cyanotoxins from the 2014 Cyanobacterial Bloom in Green Lake, Seattle. Environ Sci Technol. 2015 Dec 15; 49(24):14301-10. Teta R, Della Sala G, Glukhov E, Gerwick L, Gerwick WH, Mangoni A, Costantino V. PMID: 26567695; PMCID: PMC4851459.
      View in: PubMed   Mentions: 25     Fields:    Translation:Cells
    129. Integrating mass spectrometry and genomics for cyanobacterial metabolite discovery. J Ind Microbiol Biotechnol. 2016 Mar; 43(2-3):313-24. Moss NA, Bertin MJ, Kleigrewe K, Leão TF, Gerwick L, Gerwick WH. PMID: 26578313; PMCID: PMC5065021.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    130. Bromo-honaucin A inhibits osteoclastogenic differentiation in RAW 264.7 cells via Akt and ERK signaling pathways. Eur J Pharmacol. 2015 Dec 15; 769:100-9. Sapkota M, Li L, Choi H, Gerwick WH, Soh Y. PMID: 26550952; PMCID: PMC4684412.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    131. Structural Basis for Cyclopropanation by a Unique Enoyl-Acyl Carrier Protein Reductase. Structure. 2015 Dec 01; 23(12):2213-2223. Khare D, Hale WA, Tripathi A, Gu L, Sherman DH, Gerwick WH, Håkansson K, Smith JL. PMID: 26526850; PMCID: PMC4670573.
      View in: PubMed   Mentions: 17     Fields:    Translation:Cells
    132. Minimum Information about a Biosynthetic Gene cluster. Nat Chem Biol. 2015 Sep; 11(9):625-31. Medema MH, Kottmann R, Yilmaz P, Cummings M, Biggins JB, Blin K, de Bruijn I, Chooi YH, Claesen J, Coates RC, Cruz-Morales P, Duddela S, Düsterhus S, Edwards DJ, Fewer DP, Garg N, Geiger C, Gomez-Escribano JP, Greule A, Hadjithomas M, Haines AS, Helfrich EJ, Hillwig ML, Ishida K, Jones AC, Jones CS, Jungmann K, Kegler C, Kim HU, Kötter P, Krug D, Masschelein J, Melnik AV, Mantovani SM, Monroe EA, Moore M, Moss N, Nützmann HW, Pan G, Pati A, Petras D, Reen FJ, Rosconi F, Rui Z, Tian Z, Tobias NJ, Tsunematsu Y, Wiemann P, Wyckoff E, Yan X, Yim G, Yu F, Xie Y, Aigle B, Apel AK, Balibar CJ, Balskus EP, Barona-Gómez F, Bechthold A, Bode HB, Borriss R, Brady SF, Brakhage AA, Caffrey P, Cheng YQ, Clardy J, Cox RJ, De Mot R, Donadio S, Donia MS, van der Donk WA, Dorrestein PC, Doyle S, Driessen AJ, Ehling-Schulz M, Entian KD, Fischbach MA, Gerwick L, Gerwick WH, Gross H, Gust B, Hertweck C, Höfte M, Jensen SE, Ju J, Katz L, Kaysser L, Klassen JL, Keller NP, Kormanec J, Kuipers OP, Kuzuyama T, Kyrpides NC, Kwon HJ, Lautru S, Lavigne R, Lee CY, Linquan B, Liu X, Liu W, Luzhetskyy A, Mahmud T, Mast Y, Méndez C, Metsä-Ketelä M, Micklefield J, Mitchell DA, Moore BS, Moreira LM, Müller R, Neilan BA, Nett M, Nielsen J, O'Gara F, Oikawa H, Osbourn A, Osburne MS, Ostash B, Payne SM, Pernodet JL, Petricek M, Piel J, Ploux O, Raaijmakers JM, Salas JA, Schmitt EK, Scott B, Seipke RF, Shen B, Sherman DH, Sivonen K, Smanski MJ, Sosio M, Stegmann E, Süssmuth RD, Tahlan K, Thomas CM, Tang Y, Truman AW, Viaud M, Walton JD, Walsh CT, Weber T, van Wezel GP, Wilkinson B, Willey JM, Wohlleben W, Wright GD, Ziemert N, Zhang C, Zotchev SB, Breitling R, Takano E, Glöckner FO. PMID: 26284661; PMCID: PMC5714517.
      View in: PubMed   Mentions: 379     Fields:    Translation:AnimalsCells
    133. Bastimolide A, a Potent Antimalarial Polyhydroxy Macrolide from the Marine Cyanobacterium Okeania hirsuta. J Org Chem. 2015 Aug 21; 80(16):7849-55. Shao CL, Linington RG, Balunas MJ, Centeno A, Boudreau P, Zhang C, Engene N, Spadafora C, Mutka TS, Kyle DE, Gerwick L, Wang CY, Gerwick WH. PMID: 26222145.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    134. Biosynthesis-assisted structural elucidation of the bartolosides, chlorinated aromatic glycolipids from cyanobacteria. Angew Chem Int Ed Engl. 2015 Sep 14; 54(38):11063-7. Leão PN, Nakamura H, Costa M, Pereira AR, Martins R, Vasconcelos V, Gerwick WH, Balskus EP. PMID: 26235728; PMCID: PMC5687511.
      View in: PubMed   Mentions: 22     Fields:    Translation:Cells
    135. Expanding the Described Metabolome of the Marine Cyanobacterium Moorea producens JHB through Orthogonal Natural Products Workflows. PLoS One. 2015; 10(7):e0133297. Boudreau PD, Monroe EA, Mehrotra S, Desfor S, Korobeynikov A, Sherman DH, Murray TF, Gerwick L, Dorrestein PC, Gerwick WH. PMID: 26222584; PMCID: PMC4519256.
      View in: PubMed   Mentions: 16     Fields:    Translation:Cells
    136. Changes in secondary metabolic profiles of Microcystis aeruginosa strains in response to intraspecific interactions. Environ Microbiol. 2016 Feb; 18(2):384-400. Briand E, Bormans M, Gugger M, Dorrestein PC, Gerwick WH. PMID: 25980449; PMCID: PMC5083810.
      View in: PubMed   Mentions: 31     Fields:    Translation:Cells
    137. Combining Mass Spectrometric Metabolic Profiling with Genomic Analysis: A Powerful Approach for Discovering Natural Products from Cyanobacteria. J Nat Prod. 2015 Jul 24; 78(7):1671-82. Kleigrewe K, Almaliti J, Tian IY, Kinnel RB, Korobeynikov A, Monroe EA, Duggan BM, Di Marzo V, Sherman DH, Dorrestein PC, Gerwick L, Gerwick WH. PMID: 26149623; PMCID: PMC4681511.
      View in: PubMed   Mentions: 65     Fields:    Translation:Cells
    138. Special issue in honor of William Fenical, a pioneer in marine natural products discovery and drug development. J Nat Prod. 2015 Mar 27; 78(3):347-8. Moore BS, Gerwick WH. PMID: 25814030.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    139. Kalkitoxin inhibits angiogenesis, disrupts cellular hypoxic signaling, and blocks mitochondrial electron transport in tumor cells. Mar Drugs. 2015 Mar 20; 13(3):1552-68. Morgan JB, Liu Y, Coothankandaswamy V, Mahdi F, Jekabsons MB, Gerwick WH, Valeriote FA, Zhou YD, Nagle DG. PMID: 25803180; PMCID: PMC4377999.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    140. Gargantulide A, a complex 52-membered macrolactone showing antibacterial activity from Streptomyces sp. Org Lett. 2015 Mar 20; 17(6):1377-80. Rho JR, Subramaniam G, Choi H, Kim EH, Ng SP, Yoganathan K, Ng S, Buss AD, Butler MS, Gerwick WH. PMID: 25723256; PMCID: PMC5125438.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    141. Involvement of JNK and caspase activation in hoiamide A-induced neurotoxicity in neocortical neurons. Mar Drugs. 2015 Feb 10; 13(2):903-19. Cao Z, Li X, Zou X, Greenwood M, Gerwick WH, Murray TF. PMID: 25675001; PMCID: PMC4344608.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    142. Spongosine production by a Vibrio harveyi strain associated with the sponge Tectitethya crypta. J Nat Prod. 2015 Mar 27; 78(3):493-9. Bertin MJ, Schwartz SL, Lee J, Korobeynikov A, Dorrestein PC, Gerwick L, Gerwick WH. PMID: 25668560; PMCID: PMC5065018.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    143. Depsipeptide companeramides from a Panamanian marine cyanobacterium associated with the coibamide producer. J Nat Prod. 2015 Mar 27; 78(3):413-20. Vining OB, Medina RA, Mitchell EA, Videau P, Li D, Serrill JD, Kelly JX, Gerwick WH, Proteau PJ, Ishmael JE, McPhail KL. PMID: 25562664; PMCID: PMC4380200.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    144. Detailed analysis of (-)-palmyrolide a and some synthetic derivatives as voltage-gated sodium channel antagonists. J Nat Prod. 2014 Nov 26; 77(11):2553-60. Mehrotra S, Duggan BM, Tello-Aburto R, Newar TD, Gerwick WH, Murray TF, Maio WA. PMID: 25343669; PMCID: PMC4251536.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    145. Enantioselective divergent syntheses of several polyhalogenated Plocamium monoterpenes and evaluation of their selectivity for solid tumors. Angew Chem Int Ed Engl. 2014 Nov 03; 53(45):12205-9. Vogel CV, Pietraszkiewicz H, Sabry OM, Gerwick WH, Valeriote FA, Vanderwal CD. PMID: 25220828; PMCID: PMC4219742.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    146. Mooreamide A: a cannabinomimetic lipid from the marine cyanobacterium Moorea bouillonii. Lipids. 2014 Nov; 49(11):1127-32. Mevers E, Matainaho T, Allara' M, Di Marzo V, Gerwick WH. PMID: 25204580.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    147. Microbiota of healthy corals are active against fungi in a light-dependent manner. ACS Chem Biol. 2014 Oct 17; 9(10):2300-8. Moree WJ, McConnell OJ, Nguyen DD, Sanchez LM, Yang YL, Zhao X, Liu WT, Boudreau PD, Srinivasan J, Atencio L, Ballesteros J, Gavilán RG, Torres-Mendoza D, Guzmán HM, Gerwick WH, Gutiérrez M, Dorrestein PC. PMID: 25058318; PMCID: PMC4201335.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    148. Enzyme inhibition by hydroamination: design and mechanism of a hybrid carmaphycin-syringolin enone proteasome inhibitor. Chem Biol. 2014 Jun 19; 21(6):782-91. Trivella DB, Pereira AR, Stein ML, Kasai Y, Byrum T, Valeriote FA, Tantillo DJ, Groll M, Gerwick WH, Moore BS. PMID: 24930969; PMCID: PMC4103027.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    149. Polyhydroxy cyclohexanols from a Dendrodochium sp. fungus associated with the sea cucumber Holothuria nobilis Selenka. J Nat Prod. 2014 May 23; 77(5):1179-84. Xu DX, Sun P, Kurtán T, Mándi A, Tang H, Liu B, Gerwick WH, Wang ZW, Zhang W. PMID: 24749951.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    150. New steroids with a rearranged skeleton as (h)P300 inhibitors from the sponge Theonella swinhoei. Org Lett. 2014 Apr 18; 16(8):2224-7. Gong J, Sun P, Jiang N, Riccio R, Lauro G, Bifulco G, Li TJ, Gerwick WH, Zhang W. PMID: 24694058.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    151. Chemical and bioactive natural products from Microthyriaceae sp., an endophytic fungus from a tropical grass. Lett Appl Microbiol. 2014 Jul; 59(1):58-64. Almeida C, Ortega H, Higginbotham S, Spadafora C, Arnold AE, Coley PD, Kursar TA, Gerwick WH, Cubilla-Rios L. PMID: 24612068.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    152. Lipopeptides from the tropical marine cyanobacterium Symploca sp. J Nat Prod. 2014 Apr 25; 77(4):969-75. Mevers E, Haeckl FP, Boudreau PD, Byrum T, Dorrestein PC, Valeriote FA, Gerwick WH. PMID: 24588245; PMCID: PMC4002153.
      View in: PubMed   Mentions: 6     Fields:    Translation:Cells
    153. Briarane diterpenes from the South China Sea gorgonian coral, Junceella gemmacea. Mar Drugs. 2014 Jan 27; 12(2):589-600. Zhou W, Li J, E HC, Liu BS, Tang H, Gerwick WH, Hua HM, Zhang W. PMID: 24473165; PMCID: PMC3944505.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    154. Characterization of cyanobacterial hydrocarbon composition and distribution of biosynthetic pathways. PLoS One. 2014; 9(1):e85140. Coates RC, Podell S, Korobeynikov A, Lapidus A, Pevzner P, Sherman DH, Allen EE, Gerwick L, Gerwick WH. PMID: 24475038; PMCID: PMC3903477.
      View in: PubMed   Mentions: 58     Fields:    Translation:Cells
    155. Coibacins A and B: total synthesis and stereochemical revision. J Org Chem. 2014 Jan 17; 79(2):630-42. Carneiro VM, Avila CM, Balunas MJ, Gerwick WH, Pilli RA. PMID: 24359482; PMCID: PMC3962765.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
    156. The marine cyanobacterial metabolite gallinamide A is a potent and selective inhibitor of human cathepsin L. J Nat Prod. 2014 Jan 24; 77(1):92-9. Miller B, Friedman AJ, Choi H, Hogan J, McCammon JA, Hook V, Gerwick WH. PMID: 24364476; PMCID: PMC3932306.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    157. Quantitative molecular networking to profile marine cyanobacterial metabolomes. J Antibiot (Tokyo). 2014 Jan; 67(1):105-12. Winnikoff JR, Glukhov E, Watrous J, Dorrestein PC, Gerwick WH. PMID: 24281659; PMCID: PMC5105604.
      View in: PubMed   Mentions: 26     Fields:    Translation:Cells
    158. Metabolic engineering of lipid catabolism increases microalgal lipid accumulation without compromising growth. Proc Natl Acad Sci U S A. 2013 Dec 03; 110(49):19748-53. Trentacoste EM, Shrestha RP, Smith SR, Glé C, Hartmann AC, Hildebrand M, Gerwick WH. PMID: 24248374; PMCID: PMC3856844.
      View in: PubMed   Mentions: 97     Fields:    Translation:Animals
    159. Cyanobacterial polyketide synthase docking domains: a tool for engineering natural product biosynthesis. Chem Biol. 2013 Nov 21; 20(11):1340-51. Whicher JR, Smaga SS, Hansen DA, Brown WC, Gerwick WH, Sherman DH, Smith JL. PMID: 24183970; PMCID: PMC3870462.
      View in: PubMed   Mentions: 49     Fields:    Translation:Cells
    160. Santacruzamate A, a potent and selective histone deacetylase inhibitor from the Panamanian marine cyanobacterium cf. Symploca sp. J Nat Prod. 2013 Nov 22; 76(11):2026-33. Pavlik CM, Wong CY, Ononye S, Lopez DD, Engene N, McPhail KL, Gerwick WH, Balunas MJ. PMID: 24164245; PMCID: PMC3879121.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    161. MS/MS-based networking and peptidogenomics guided genome mining revealed the stenothricin gene cluster in Streptomyces roseosporus. J Antibiot (Tokyo). 2014 Jan; 67(1):99-104. Liu WT, Lamsa A, Wong WR, Boudreau PD, Kersten R, Peng Y, Moree WJ, Duggan BM, Moore BS, Gerwick WH, Linington RG, Pogliano K, Dorrestein PC. PMID: 24149839; PMCID: PMC3919142.
      View in: PubMed   Mentions: 34     Fields:    Translation:Cells
    162. Five chemically rich species of tropical marine cyanobacteria of the genus Okeania gen. nov. (Oscillatoriales, Cyanoprokaryota). J Phycol. 2013 Dec; 49(6):1095-106. Engene N, Paul VJ, Byrum T, Gerwick WH, Thor A, Ellisman MH. PMID: 27007630.
      View in: PubMed   Mentions: 21     Fields:    
    163. Parguerene and precarriebowmide, two classes of lipopeptides from the marine cyanobacterium Moorea producens. J Nat Prod. 2013 Sep 27; 76(9):1810-4. Mevers E, Byrum T, Gerwick WH. PMID: 24044577; PMCID: PMC3962764.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    164. Molecular networking as a dereplication strategy. J Nat Prod. 2013 Sep 27; 76(9):1686-99. Yang JY, Sanchez LM, Rath CM, Liu X, Boudreau PD, Bruns N, Glukhov E, Wodtke A, de Felicio R, Fenner A, Wong WR, Linington RG, Zhang L, Debonsi HM, Gerwick WH, Dorrestein PC. PMID: 24025162; PMCID: PMC3936340.
      View in: PubMed   Mentions: 232     Fields:    Translation:Cells
    165. Bouillonamide: a mixed polyketide-peptide cytotoxin from the marine cyanobacterium Moorea bouillonii. Mar Drugs. 2013 Aug 19; 11(8):3015-24. Tan LT, Okino T, Gerwick WH. PMID: 23966034; PMCID: PMC3766879.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    166. Antitumor activity of hierridin B, a cyanobacterial secondary metabolite found in both filamentous and unicellular marine strains. PLoS One. 2013; 8(7):e69562. Leão PN, Costa M, Ramos V, Pereira AR, Fernandes VC, Domingues VF, Gerwick WH, Vasconcelos VM, Martins R. PMID: 23922738; PMCID: PMC3726634.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    167. Polyketide genes in the marine sponge Plakortis simplex: a new group of mono-modular type I polyketide synthases from sponge symbionts. Environ Microbiol Rep. 2013 Dec; 5(6):809-18. Della Sala G, Hochmuth T, Costantino V, Teta R, Gerwick W, Gerwick L, Piel J, Mangoni A. PMID: 24249289; PMCID: PMC3908369.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    168. High-titer heterologous production in E. coli of lyngbyatoxin, a protein kinase C activator from an uncultured marine cyanobacterium. ACS Chem Biol. 2013 Sep 20; 8(9):1888-93. Ongley SE, Bian X, Zhang Y, Chau R, Gerwick WH, Müller R, Neilan BA. PMID: 23751865; PMCID: PMC3880125.
      View in: PubMed   Mentions: 25     Fields:    Translation:Cells
    169. Chemoecological screening reveals high bioactivity in diverse culturable Portuguese marine cyanobacteria. Mar Drugs. 2013 Apr 22; 11(4):1316-35. Leão PN, Ramos V, Gonçalves PB, Viana F, Lage OM, Gerwick WH, Vasconcelos VM. PMID: 23609580; PMCID: PMC3705407.
      View in: PubMed   Mentions: 8     Fields:    Translation:Cells
    170. Mycoleptodiscins A and B, cytotoxic alkaloids from the endophytic fungus Mycoleptodiscus sp. F0194. J Nat Prod. 2013 Apr 26; 76(4):741-4. Ortega HE, Graupner PR, Asai Y, Tendyke K, Qiu D, Shen YY, Rios N, Arnold AE, Coley PD, Kursar TA, Gerwick WH, Cubilla-Rios L. PMID: 23560689.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    171. Phylogenetic inferences reveal a large extent of novel biodiversity in chemically rich tropical marine cyanobacteria. Appl Environ Microbiol. 2013 Mar; 79(6):1882-8. Engene N, Gunasekera SP, Gerwick WH, Paul VJ. PMID: 23315747; PMCID: PMC3592240.
      View in: PubMed   Mentions: 14     Fields:    Translation:Cells
    172. Drug discovery from marine microbes. Microb Ecol. 2013 May; 65(4):800-6. Gerwick WH, Fenner AM. PMID: 23274881; PMCID: PMC3640700.
      View in: PubMed   Mentions: 38     Fields:    Translation:AnimalsCells
    173. Heterologous production of 4-O-demethylbarbamide, a marine cyanobacterial natural product. Org Lett. 2012 Dec 07; 14(23):5824-7. Kim EJ, Lee JH, Choi H, Pereira AR, Ban YH, Yoo YJ, Kim E, Park JW, Sherman DH, Gerwick WH, Yoon YJ. PMID: 23148802; PMCID: PMC3536539.
      View in: PubMed   Mentions: 24     Fields:    Translation:Cells
    174. Bidirectional influence of sodium channel activation on NMDA receptor-dependent cerebrocortical neuron structural plasticity. Proc Natl Acad Sci U S A. 2012 Nov 27; 109(48):19840-5. George J, Baden DG, Gerwick WH, Murray TF. PMID: 23150561; PMCID: PMC3511701.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    175. Structural basis of functional group activation by sulfotransferases in complex metabolic pathways. ACS Chem Biol. 2012 Dec 21; 7(12):1994-2003. McCarthy JG, Eisman EB, Kulkarni S, Gerwick L, Gerwick WH, Wipf P, Sherman DH, Smith JL. PMID: 22991895; PMCID: PMC3528841.
      View in: PubMed   Mentions: 13     Fields:    Translation:Cells
    176. Viequeamide A, a cytotoxic member of the kulolide superfamily of cyclic depsipeptides from a marine button cyanobacterium. J Nat Prod. 2012 Sep 28; 75(9):1560-70. Boudreau PD, Byrum T, Liu WT, Dorrestein PC, Gerwick WH. PMID: 22924493; PMCID: PMC3521035.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    177. Lyngbyabellins K-N from Two Palmyra Atoll Collections of the Marine Cyanobacterium Moorea bouillonii. European J Org Chem. 2012 Sep 01; 2012(27):5141-5150. Choi H, Mevers E, Byrum T, Valeriote FA, Gerwick WH. PMID: 24574859; PMCID: PMC3932497.
      View in: PubMed   Mentions: 29  
    178. Coibacins A-D, antileishmanial marine cyanobacterial polyketides with intriguing biosynthetic origins. Org Lett. 2012 Aug 03; 14(15):3878-81. Balunas MJ, Grosso MF, Villa FA, Engene N, McPhail KL, Tidgewell K, Pineda LM, Gerwick L, Spadafora C, Kyle DE, Gerwick WH. PMID: 22794317; PMCID: PMC3449157.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    179. Observing the invisible through imaging mass spectrometry, a window into the metabolic exchange patterns of microbes. J Proteomics. 2012 Aug 30; 75(16):5069-5076. Gonzalez DJ, Xu Y, Yang YL, Esquenazi E, Liu WT, Edlund A, Duong T, Du L, Molnár I, Gerwick WH, Jensen PR, Fischbach M, Liaw CC, Straight P, Nizet V, Dorrestein PC. PMID: 22641157; PMCID: PMC3543690.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    180. Honaucins A-C, potent inhibitors of inflammation and bacterial quorum sensing: synthetic derivatives and structure-activity relationships. Chem Biol. 2012 May 25; 19(5):589-98. Choi H, Mascuch SJ, Villa FA, Byrum T, Teasdale ME, Smith JE, Preskitt LB, Rowley DC, Gerwick L, Gerwick WH. PMID: 22633410; PMCID: PMC3361693.
      View in: PubMed   Mentions: 42     Fields:    Translation:AnimalsCells
    181. Biosynthetically intriguing chlorinated lipophilic metabolites from geographically distant tropical marine cyanobacteria. J Org Chem. 2012 May 04; 77(9):4198-208. Nunnery JK, Engene N, Byrum T, Cao Z, Jabba SV, Pereira AR, Matainaho T, Murray TF, Gerwick WH. PMID: 22489775; PMCID: PMC3345101.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    182. Exploiting adaptive laboratory evolution of Streptomyces clavuligerus for antibiotic discovery and overproduction. PLoS One. 2012; 7(3):e33727. Charusanti P, Fong NL, Nagarajan H, Pereira AR, Li HJ, Abate EA, Su Y, Gerwick WH, Palsson BO. PMID: 22470465; PMCID: PMC3312335.
      View in: PubMed   Mentions: 33     Fields:    Translation:Cells
    183. Evaluation of Streptomyces coelicolor A3(2) as a heterologous expression host for the cyanobacterial protein kinase C activator lyngbyatoxin A. FEBS J. 2012 Apr; 279(7):1243-51. Jones AC, Ottilie S, Eustáquio AS, Edwards DJ, Gerwick L, Moore BS, Gerwick WH. PMID: 22314229.
      View in: PubMed   Mentions: 11     Fields:    Translation:Cells
    184. The carmaphycins: new proteasome inhibitors exhibiting an α,β-epoxyketone warhead from a marine cyanobacterium. Chembiochem. 2012 Apr 16; 13(6):810-7. Pereira AR, Kale AJ, Fenley AT, Byrum T, Debonsi HM, Gilson MK, Valeriote FA, Moore BS, Gerwick WH. PMID: 22383253; PMCID: PMC3393770.
      View in: PubMed   Mentions: 46     Fields:    Translation:AnimalsCells
    185. Coibanoles, a new class of meroterpenoids produced by Pycnoporus sanguineus. Tetrahedron Lett. 2012 Feb 20; 53(8):919-922. Molinar E, Rios N, Spadafora C, Arnold AE, Coley PD, Kursar TA, Gerwick WH, Cubilla-Rios L. PMID: 25177062; PMCID: PMC4148033.
      View in: PubMed   Mentions: 7     Fields:    
    186. Antiparasitic and anticancer constituents of the endophytic fungus Aspergillus sp. strain F1544. Nat Prod Commun. 2012 Feb; 7(2):165-8. Martínez-Luis S, Cherigo L, Arnold E, Spadafora C, Gerwick WH, Cubilla-Rios L. PMID: 22474943.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    187. Antifungal Depsidone Metabolites from Cordyceps dipterigena, an Endophytic Fungus Antagonistic to the Phytopathogen Gibberella fujikuroi. Tetrahedron Lett. 2012 Mar 28; 53(13):1624-1626. Varughese T, Riosa N, Higginbotham S, Arnold AE, Coley PD, Kursar TA, Gerwick WH, Cubilla Rios L. PMID: 22707798; PMCID: PMC3375120.
      View in: PubMed   Mentions: 9     Fields:    
    188. Lessons from the past and charting the future of marine natural products drug discovery and chemical biology. Chem Biol. 2012 Jan 27; 19(1):85-98. Gerwick WH, Moore BS. PMID: 22284357; PMCID: PMC3345185.
      View in: PubMed   Mentions: 202     Fields:    Translation:Humans
    189. The chemical ecology of cyanobacteria. Nat Prod Rep. 2012 Mar; 29(3):372-91. Leão PN, Engene N, Antunes A, Gerwick WH, Vasconcelos V. PMID: 22237837; PMCID: PMC4161925.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansCells
    190. Structure and activity of DmmA, a marine haloalkane dehalogenase. Protein Sci. 2012 Feb; 21(2):239-48. Gehret JJ, Gu L, Geders TW, Brown WC, Gerwick L, Gerwick WH, Sherman DH, Smith JL. PMID: 22124946; PMCID: PMC3324768.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    191. Credneramides A and B: neuromodulatory phenethylamine and isopentylamine derivatives of a vinyl chloride-containing fatty acid from cf. Trichodesmium sp. nov. J Nat Prod. 2012 Jan 27; 75(1):60-6. Malloy KL, Suyama TL, Engene N, Debonsi H, Cao Z, Matainaho T, Spadafora C, Murray TF, Gerwick WH. PMID: 22148360; PMCID: PMC3336157.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    192. Cymatherelactone and cymatherols A-C, polycyclic oxylipins from the marine brown alga Cymathere triplicata. Phytochemistry. 2012 Jan; 73(1):134-41. Choi H, Proteau PJ, Byrum T, Pereira AR, Gerwick WH. PMID: 22071135.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    193. Hoiamide D, a marine cyanobacteria-derived inhibitor of p53/MDM2 interaction. Bioorg Med Chem Lett. 2012 Jan 01; 22(1):683-8. Malloy KL, Choi H, Fiorilla C, Valeriote FA, Matainaho T, Gerwick WH. PMID: 22104152; PMCID: PMC3248991.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    194. Cannabinomimetic lipid from a marine cyanobacterium. J Nat Prod. 2011 Oct 28; 74(10):2313-7. Gutiérrez M, Pereira AR, Debonsi HM, Ligresti A, Di Marzo V, Gerwick WH. PMID: 21999614; PMCID: PMC3325759.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    195. Wewakamide A and guineamide G, cyclic depsipeptides from the marine cyanobacteria Lyngbya semiplena and Lyngbya majuscula. J Microbiol Biotechnol. 2011 Sep; 21(9):930-6. Han B, Gross H, McPhail KL, Goeger D, Maier CS, Gerwick WH. PMID: 21952369.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    196. Phylogeny-guided isolation of ethyl tumonoate A from the marine cyanobacterium cf. Oscillatoria margaritifera. J Nat Prod. 2011 Aug 26; 74(8):1737-43. Engene N, Choi H, Esquenazi E, Byrum T, Villa FA, Cao Z, Murray TF, Dorrestein PC, Gerwick L, Gerwick WH. PMID: 21751786; PMCID: PMC3163041.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    197. Moorea producens gen. nov., sp. nov. and Moorea bouillonii comb. nov., tropical marine cyanobacteria rich in bioactive secondary metabolites. Int J Syst Evol Microbiol. 2012 May; 62(Pt 5):1171-1178. Engene N, Rottacker EC, Kaštovský J, Byrum T, Choi H, Ellisman MH, Komárek J, Gerwick WH. PMID: 21724952; PMCID: PMC3542135.
      View in: PubMed   Mentions: 68     Fields:    Translation:Cells
    198. Ion mobility mass spectrometry enables the efficient detection and identification of halogenated natural products from cyanobacteria with minimal sample preparation. Bioorg Med Chem. 2011 Nov 15; 19(22):6639-44. Esquenazi E, Daly M, Bahrainwala T, Gerwick WH, Dorrestein PC. PMID: 21784647.
      View in: PubMed   Mentions: 10     Fields:    Translation:Cells
    199. Probing the in vivo biosynthesis of scytonemin, a cyanobacterial ultraviolet radiation sunscreen, through small scale stable isotope incubation studies and MALDI-TOF mass spectrometry. Bioorg Med Chem. 2011 Nov 15; 19(22):6620-7. Jones CS, Esquenazi E, Dorrestein PC, Gerwick WH. PMID: 21742508; PMCID: PMC3227548.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    200. Survey of marine natural product structure revisions: a synergy of spectroscopy and chemical synthesis. Bioorg Med Chem. 2011 Nov 15; 19(22):6675-701. Suyama TL, Gerwick WH, McPhail KL. PMID: 21715178; PMCID: PMC3205310.
      View in: PubMed   Mentions: 25     Fields:    Translation:Animals
    201. Expedient synthesis of α,α-dimethyl-β-hydroxy carbonyl scaffolds via Evans' aldol reaction with a tertiary enolate. Tetrahedron Lett. 2011 Jun 08; 52(23):2929-2932. Nunnery JK, Suyama TL, Linington RG, Gerwick WH. PMID: 21617761; PMCID: PMC3100194.
      View in: PubMed   Mentions: 3     Fields:    
    202. Screening and evaluation of antiparasitic and in vitro anticancer activities of Panamanian endophytic fungi. Int Microbiol. 2011 Jun; 14(2):95-102. Martínez-Luis S, Cherigo L, Higginbotham S, Arnold E, Spadafora C, Ibañez A, Gerwick WH, Cubilla-Rios L. PMID: 22069153; PMCID: PMC3375117.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    203. Chemical constituents of the new endophytic fungus Mycosphaerella sp. nov. and their anti-parasitic activity. Nat Prod Commun. 2011 Jun; 6(6):835-40. Moreno E, Varughese T, Spadafora C, Arnold AE, Coley PD, Kursar TA, Gerwick WH, Cubilla-Rios L. PMID: 21815421; PMCID: PMC3375898.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    204. Genomic insights into the physiology and ecology of the marine filamentous cyanobacterium Lyngbya majuscula. Proc Natl Acad Sci U S A. 2011 May 24; 108(21):8815-20. Jones AC, Monroe EA, Podell S, Hess WR, Klages S, Esquenazi E, Niessen S, Hoover H, Rothmann M, Lasken RS, Yates JR, Reinhardt R, Kube M, Burkart MD, Allen EE, Dorrestein PC, Gerwick WH, Gerwick L. PMID: 21555588; PMCID: PMC3102346.
      View in: PubMed   Mentions: 41     Fields:    Translation:Cells
    205. Significant natural product biosynthetic potential of actinorhizal symbionts of the genus frankia, as revealed by comparative genomic and proteomic analyses. Appl Environ Microbiol. 2011 Jun; 77(11):3617-25. Udwary DW, Gontang EA, Jones AC, Jones CS, Schultz AW, Winter JM, Yang JY, Beauchemin N, Capson TL, Clark BR, Esquenazi E, Eustáquio AS, Freel K, Gerwick L, Gerwick WH, Gonzalez D, Liu WT, Malloy KL, Maloney KN, Nett M, Nunnery JK, Penn K, Prieto-Davo A, Simmons TL, Weitz S, Wilson MC, Tisa LS, Dorrestein PC, Moore BS. PMID: 21498757; PMCID: PMC3127629.
      View in: PubMed   Mentions: 37     Fields:    Translation:Cells
    206. Cytotoxic veraguamides, alkynyl bromide-containing cyclic depsipeptides from the marine cyanobacterium cf. Oscillatoria margaritifera. J Nat Prod. 2011 May 27; 74(5):928-36. Mevers E, Liu WT, Engene N, Mohimani H, Byrum T, Pevzner PA, Dorrestein PC, Spadafora C, Gerwick WH. PMID: 21488639; PMCID: PMC3103610.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansCells
    207. Single cell genome amplification accelerates identification of the apratoxin biosynthetic pathway from a complex microbial assemblage. PLoS One. 2011 Apr 12; 6(4):e18565. Grindberg RV, Ishoey T, Brinza D, Esquenazi E, Coates RC, Liu WT, Gerwick L, Dorrestein PC, Pevzner P, Lasken R, Gerwick WH. PMID: 21533272; PMCID: PMC3075265.
      View in: PubMed   Mentions: 50     Fields:    Translation:Cells
    208. Molluscicidal metabolites from an assemblage of Palmyra Atoll cyanobacteria. J Nat Prod. 2011 May 27; 74(5):1175-81. Pereira AR, Etzbach L, Engene N, Müller R, Gerwick WH. PMID: 21473610; PMCID: PMC3227552.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    209. Underestimated biodiversity as a major explanation for the perceived rich secondary metabolite capacity of the cyanobacterial genus Lyngbya. Environ Microbiol. 2011 Jun; 13(6):1601-10. Engene N, Choi H, Esquenazi E, Rottacker EC, Ellisman MH, Dorrestein PC, Gerwick WH. PMID: 21477107; PMCID: PMC3131211.
      View in: PubMed   Mentions: 28     Fields:    Translation:Cells
    210. Elegant metabolite biosynthesis. Chem Biol. 2011 Mar 25; 18(3):281-3. Jones AC, Monroe EA, Gerwick WH. PMID: 21439471.
      View in: PubMed   Mentions:    Fields:    
    211. The structure elucidation of isomalyngamide K from the marine cyanobacterium Lyngbya majuscula by experimental and DFT computational methods. J Mol Struct. 2011 Mar 15; 989(1-3):109-113. Han B, Reinscheid UM, Gerwick WH, Gross H. PMID: 21461120; PMCID: PMC3066435.
      View in: PubMed   Mentions: 5  
    212. Temporal dynamics of natural product biosynthesis in marine cyanobacteria. Proc Natl Acad Sci U S A. 2011 Mar 29; 108(13):5226-31. Esquenazi E, Jones AC, Byrum T, Dorrestein PC, Gerwick WH. PMID: 21393570; PMCID: PMC3069200.
      View in: PubMed   Mentions: 18     Fields:    Translation:Cells
    213. Terminal alkene formation by the thioesterase of curacin A biosynthesis: structure of a decarboxylating thioesterase. J Biol Chem. 2011 Apr 22; 286(16):14445-54. Gehret JJ, Gu L, Gerwick WH, Wipf P, Sherman DH, Smith JL. PMID: 21357626; PMCID: PMC3077644.
      View in: PubMed   Mentions: 26     Fields:    Translation:Cells
    214. Tandem acyl carrier proteins in the curacin biosynthetic pathway promote consecutive multienzyme reactions with a synergistic effect. Angew Chem Int Ed Engl. 2011 Mar 14; 50(12):2795-8. Gu L, Eisman EB, Dutta S, Franzmann TM, Walter S, Gerwick WH, Skiniotis G, Sherman DH. PMID: 21387490; PMCID: PMC3081611.
      View in: PubMed   Mentions: 21     Fields:    Translation:Cells
    215. Antillatoxin is a sodium channel activator that displays unique efficacy in heterologously expressed rNav1.2, rNav1.4 and rNav1.5 α subunits. BMC Neurosci. 2010 Dec 14; 11:154. Cao Z, Gerwick WH, Murray TF. PMID: 21156065; PMCID: PMC3009643.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    216. Malyngamide 2, an oxidized lipopeptide with nitric oxide inhibiting activity from a Papua New Guinea marine cyanobacterium. J Nat Prod. 2011 Jan 28; 74(1):95-8. Malloy KL, Villa FA, Engene N, Matainaho T, Gerwick L, Gerwick WH. PMID: 21155594; PMCID: PMC3227558.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    217. Biologically active secondary metabolites from marine cyanobacteria. Curr Opin Biotechnol. 2010 Dec; 21(6):787-93. Nunnery JK, Mevers E, Gerwick WH. PMID: 21030245; PMCID: PMC3034308.
      View in: PubMed   Mentions: 59     Fields:    Translation:Cells
    218. Palmyrolide A, an unusually stabilized neuroactive macrolide from Palmyra Atoll cyanobacteria. Org Lett. 2010 Oct 15; 12(20):4490-3. Pereira AR, Cao Z, Engene N, Soria-Mercado IE, Murray TF, Gerwick WH. PMID: 20845912; PMCID: PMC2965064.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    219. The hoiamides, structurally intriguing neurotoxic lipopeptides from Papua New Guinea marine cyanobacteria. J Nat Prod. 2010 Aug 27; 73(8):1411-21. Choi H, Pereira AR, Cao Z, Shuman CF, Engene N, Byrum T, Matainaho T, Murray TF, Mangoni A, Gerwick WH. PMID: 20687534; PMCID: PMC3227549.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    220. Two cytotoxic stereoisomers of malyngamide C, 8-epi-malyngamide C and 8-O-acetyl-8-epi-malyngamide C, from the marine cyanobacterium Lyngbya majuscula. Phytochemistry. 2010 Oct; 71(14-15):1729-35. Gross H, McPhail KL, Goeger DE, Valeriote FA, Gerwick WH. PMID: 20701935; PMCID: PMC2952490.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    221. Conformational switch triggered by alpha-ketoglutarate in a halogenase of curacin A biosynthesis. Proc Natl Acad Sci U S A. 2010 Aug 10; 107(32):14099-104. Khare D, Wang B, Gu L, Razelun J, Sherman DH, Gerwick WH, Håkansson K, Smith JL. PMID: 20660778; PMCID: PMC2922534.
      View in: PubMed   Mentions: 37     Fields:    Translation:Cells
    222. Evolved diversification of a modular natural product pathway: apratoxins F and G, two cytotoxic cyclic depsipeptides from a Palmyra collection of Lyngbya bouillonii. Chembiochem. 2010 Jul 05; 11(10):1458-66. Tidgewell K, Engene N, Byrum T, Media J, Doi T, Valeriote FA, Gerwick WH. PMID: 20512792; PMCID: PMC3521036.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansCells
    223. Synergistic allelochemicals from a freshwater cyanobacterium. Proc Natl Acad Sci U S A. 2010 Jun 22; 107(25):11183-8. Leão PN, Pereira AR, Liu WT, Ng J, Pevzner PA, Dorrestein PC, König GM, Vasconcelos VM, Gerwick WH. PMID: 20534563; PMCID: PMC2895120.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansCells
    224. Almiramides A-C: discovery and development of a new class of leishmaniasis lead compounds. J Med Chem. 2010 May 27; 53(10):4187-97. Sanchez LM, Lopez D, Vesely BA, Della Togna G, Gerwick WH, Kyle DE, Linington RG. PMID: 20441198; PMCID: PMC4418807.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    225. The unique mechanistic transformations involved in the biosynthesis of modular natural products from marine cyanobacteria. Nat Prod Rep. 2010 Jul; 27(7):1048-65. Jones AC, Monroe EA, Eisman EB, Gerwick L, Sherman DH, Gerwick WH. PMID: 20442916.
      View in: PubMed   Mentions: 34     Fields:    Translation:Cells
    226. Crossbyanols A-D, toxic brominated polyphenyl ethers from the Hawai'ian bloom-forming Cyanobacterium Leptolyngbya crossbyana. J Nat Prod. 2010 Apr 23; 73(4):517-22. Choi H, Engene N, Smith JE, Preskitt LB, Gerwick WH. PMID: 20170122; PMCID: PMC2859106.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    227. Malyngolide dimer, a bioactive symmetric cyclodepside from the panamanian marine cyanobacterium Lyngbya majuscula. J Nat Prod. 2010 Apr 23; 73(4):709-11. Gutiérrez M, Tidgewell K, Capson TL, Engene N, Almanza A, Schemies J, Jung M, Gerwick WH. PMID: 20158242; PMCID: PMC2859090.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    228. Palmyramide A, a cyclic depsipeptide from a Palmyra Atoll collection of the marine cyanobacterium Lyngbya majuscula. J Nat Prod. 2010 Mar 26; 73(3):393-8. Taniguchi M, Nunnery JK, Engene N, Esquenazi E, Byrum T, Dorrestein PC, Gerwick WH. PMID: 19839606; PMCID: PMC2862350.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansCells
    229. A concise enantioselective synthesis of the chlorosulfolipid malhamensilipin A. J Am Chem Soc. 2010 Mar 03; 132(8):2542-3. Bedke DK, Shibuya GM, Pereira AR, Gerwick WH, Vanderwal CD. PMID: 20141139; PMCID: PMC2830791.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    230. Cyanolide A, a glycosidic macrolide with potent Molluscicidal activity from the Papua New Guinea cyanobacterium Lyngbya bouillonii. J Nat Prod. 2010 Feb 26; 73(2):217-20. Pereira AR, McCue CF, Gerwick WH. PMID: 20131814; PMCID: PMC2834176.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    231. Structure revision and absolute configuration of malhamensilipin A from the freshwater chrysophyte Poterioochromonas malhamensis. J Nat Prod. 2010 Feb 26; 73(2):279-83. Pereira AR, Byrum T, Shibuya GM, Vanderwal CD, Gerwick WH. PMID: 20099812; PMCID: PMC2829345.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    232. Crystal structures of dehydratase domains from the curacin polyketide biosynthetic pathway. Structure. 2010 Jan 13; 18(1):94-105. Akey DL, Razelun JR, Tehranisa J, Sherman DH, Gerwick WH, Smith JL. PMID: 20152156; PMCID: PMC3102235.
      View in: PubMed   Mentions: 59     Fields:    Translation:Cells
    233. Dragonamide E, a modified linear lipopeptide from Lyngbya majuscula with antileishmanial activity. J Nat Prod. 2010 Jan; 73(1):60-6. Balunas MJ, Linington RG, Tidgewell K, Fenner AM, Ureña LD, Togna GD, Kyle DE, Gerwick WH. PMID: 20030365; PMCID: PMC2834186.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    234. Enzymatic production of (-)-indolactam V by LtxB, a cytochrome P450 monooxygenase. J Nat Prod. 2010 Jan; 73(1):71-4. Huynh MU, Elston MC, Hernandez NM, Ball DB, Kajiyama S, Irie K, Gerwick WH, Edwards DJ. PMID: 20000453.
      View in: PubMed   Mentions: 9     Fields:    Translation:Cells
    235. Antillatoxin, a novel lipopeptide, enhances neurite outgrowth in immature cerebrocortical neurons through activation of voltage-gated sodium channels. J Pharmacol Exp Ther. 2010 Mar; 332(3):698-709. Jabba SV, Prakash A, Dravid SM, Gerwick WH, Murray TF. PMID: 20026674; PMCID: PMC2835437.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    236. Transcriptional analysis of the jamaicamide gene cluster from the marine cyanobacterium Lyngbya majuscula and identification of possible regulatory proteins. BMC Microbiol. 2009 Dec 01; 9:247. Jones AC, Gerwick L, Gonzalez D, Dorrestein PC, Gerwick WH. PMID: 19951434; PMCID: PMC2799420.
      View in: PubMed   Mentions: 8     Fields:    Translation:Cells
    237. Polyketide decarboxylative chain termination preceded by o-sulfonation in curacin a biosynthesis. J Am Chem Soc. 2009 Nov 11; 131(44):16033-5. Gu L, Wang B, Kulkarni A, Gehret JJ, Lloyd KR, Gerwick L, Gerwick WH, Wipf P, Håkansson K, Smith JL, Sherman DH. PMID: 19835378; PMCID: PMC2839324.
      View in: PubMed   Mentions: 44     Fields:    Translation:Cells
    238. Imaging mass spectrometry of natural products. Nat Prod Rep. 2009 Dec; 26(12):1521-34. Esquenazi E, Yang YL, Watrous J, Gerwick WH, Dorrestein PC. PMID: 19936384.
      View in: PubMed   Mentions: 43     Fields:    
    239. Alotamide A, a novel neuropharmacological agent from the marine cyanobacterium Lyngbya bouillonii. Org Lett. 2009 Oct 15; 11(20):4704-7. Soria-Mercado IE, Pereira A, Cao Z, Murray TF, Gerwick WH. PMID: 19754100; PMCID: PMC2759415.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    240. Hoiamide a, a sodium channel activator of unusual architecture from a consortium of two papua new Guinea cyanobacteria. Chem Biol. 2009 Aug 28; 16(8):893-906. Pereira A, Cao Z, Murray TF, Gerwick WH. PMID: 19716479; PMCID: PMC2763540.
      View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
    241. Structural and synthetic investigations of tanikolide dimer, a SIRT2 selective inhibitor, and tanikolide seco-acid from the Madagascar marine cyanobacterium Lyngbya majuscula. J Org Chem. 2009 Aug 07; 74(15):5267-75. Gutiérrez M, Andrianasolo EH, Shin WK, Goeger DE, Yokochi A, Schemies J, Jung M, France D, Cornell-Kennon S, Lee E, Gerwick WH. PMID: 19572575; PMCID: PMC2736347.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    242. Ichthyotoxic brominated diphenyl ethers from a mixed assemblage of a red alga and cyanobacterium: structure clarification and biological properties. Toxicon. 2010 Feb-Mar; 55(2-3):204-10. Suyama TL, Cao Z, Murray TF, Gerwick WH. PMID: 19638282; PMCID: PMC2813928.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    243. Dereplication and de novo sequencing of nonribosomal peptides. Nat Methods. 2009 Aug; 6(8):596-9. Ng J, Bandeira N, Liu WT, Ghassemian M, Simmons TL, Gerwick WH, Linington R, Dorrestein PC, Pevzner PA. PMID: 19597502; PMCID: PMC2754211.
      View in: PubMed   Mentions: 37     Fields:    Translation:Cells
    244. Relative stereochemistry determination and synthesis of the major chlorosulfolipid from Ochromonas danica. J Am Chem Soc. 2009 Jun 10; 131(22):7570-2. Bedke DK, Shibuya GM, Pereira A, Gerwick WH, Haines TH, Vanderwal CD. PMID: 19445461.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    245. Metamorphic enzyme assembly in polyketide diversification. Nature. 2009 Jun 04; 459(7247):731-5. Gu L, Wang B, Kulkarni A, Geders TW, Grindberg RV, Gerwick L, Håkansson K, Wipf P, Smith JL, Gerwick WH, Sherman DH. PMID: 19494914; PMCID: PMC2918389.
      View in: PubMed   Mentions: 82     Fields:    Translation:Cells
    246. Desmethoxymajusculamide C, a cyanobacterial depsipeptide with potent cytotoxicity in both cyclic and ring-opened forms. J Nat Prod. 2009 Jun; 72(6):1011-6. Simmons TL, Nogle LM, Media J, Valeriote FA, Mooberry SL, Gerwick WH. PMID: 19489598; PMCID: PMC2857713.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    247. Interpretation of tandem mass spectra obtained from cyclic nonribosomal peptides. Anal Chem. 2009 Jun 01; 81(11):4200-9. Liu WT, Ng J, Meluzzi D, Bandeira N, Gutierrez M, Simmons TL, Schultz AW, Linington RG, Moore BS, Gerwick WH, Pevzner PA, Dorrestein PC. PMID: 19413302; PMCID: PMC2765223.
      View in: PubMed   Mentions: 36     Fields:    Translation:Cells
    248. Organization, evolution, and expression analysis of the biosynthetic gene cluster for scytonemin, a cyanobacterial UV-absorbing pigment. Appl Environ Microbiol. 2009 Jul; 75(14):4861-9. Sorrels CM, Proteau PJ, Gerwick WH. PMID: 19482954; PMCID: PMC2708446.
      View in: PubMed   Mentions: 30     Fields:    Translation:Cells
    249. Probing marine natural product defenses with DESI-imaging mass spectrometry. Proc Natl Acad Sci U S A. 2009 May 05; 106(18):7269-70. Esquenazi E, Dorrestein PC, Gerwick WH. PMID: 19416917; PMCID: PMC2678597.
      View in: PubMed   Mentions: 18     Fields:    Translation:Animals
    250. New tricks from ancient algae: natural products biosynthesis in marine cyanobacteria. Curr Opin Chem Biol. 2009 Apr; 13(2):216-23. Jones AC, Gu L, Sorrels CM, Sherman DH, Gerwick WH. PMID: 19307147; PMCID: PMC2706127.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    251. Antimalarial peptides from marine cyanobacteria: isolation and structural elucidation of gallinamide A. J Nat Prod. 2009 Jan; 72(1):14-7. Linington RG, Clark BR, Trimble EE, Almanza A, Ureña LD, Kyle DE, Gerwick WH. PMID: 19161344; PMCID: PMC2760338.
      View in: PubMed   Mentions: 42     Fields:    Translation:AnimalsCells
    252. Antileishmanial constituents of the Panamanian endophytic fungus Edenia sp. J Nat Prod. 2008 Dec; 71(12):2011-4. Martínez-Luis S, Della-Togna G, Coley PD, Kursar TA, Gerwick WH, Cubilla-Rios L. PMID: 19007286; PMCID: PMC2774465.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    253. Stereospecific total synthesis of somocystinamide A. Org Lett. 2008 Oct 16; 10(20):4449-52. Suyama TL, Gerwick WH. PMID: 18788741; PMCID: PMC3227555.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
    254. Viridamides A and B, lipodepsipeptides with antiprotozoal activity from the marine cyanobacterium Oscillatoria nigro-viridis. J Nat Prod. 2008 Sep; 71(9):1544-50. Simmons TL, Engene N, Ureña LD, Romero LI, Ortega-Barría E, Gerwick L, Gerwick WH. PMID: 18715036; PMCID: PMC2656441.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    255. Natural products chemistry and taxonomy of the marine cyanobacterium Blennothrix cantharidosmum. J Nat Prod. 2008 Sep; 71(9):1530-7. Clark BR, Engene N, Teasdale ME, Rowley DC, Matainaho T, Valeriote FA, Gerwick WH. PMID: 18698821; PMCID: PMC2657878.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    256. Influence of lipid-soluble gating modifier toxins on sodium influx in neocortical neurons. J Pharmacol Exp Ther. 2008 Aug; 326(2):604-13. Cao Z, George J, Gerwick WH, Baden DG, Rainier JD, Murray TF. PMID: 18448863; PMCID: PMC2852114.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    257. Apratoxin D, a potent cytotoxic cyclodepsipeptide from papua new guinea collections of the marine cyanobacteria Lyngbya majuscula and Lyngbya sordida. J Nat Prod. 2008 Jun; 71(6):1099-103. Gutiérrez M, Suyama TL, Engene N, Wingerd JS, Matainaho T, Gerwick WH. PMID: 18444683.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansCells
    258. Coibamide A, a potent antiproliferative cyclic depsipeptide from the Panamanian marine cyanobacterium Leptolyngbya sp. J Am Chem Soc. 2008 May 21; 130(20):6324-5. Medina RA, Goeger DE, Hills P, Mooberry SL, Huang N, Romero LI, Ortega-Barría E, Gerwick WH, McPhail KL. PMID: 18444611; PMCID: PMC2659736.
      View in: PubMed   Mentions: 75     Fields:    Translation:HumansAnimalsCells
    259. Visualizing the spatial distribution of secondary metabolites produced by marine cyanobacteria and sponges via MALDI-TOF imaging. Mol Biosyst. 2008 Jun; 4(6):562-70. Esquenazi E, Coates C, Simmons L, Gonzalez D, Gerwick WH, Dorrestein PC. PMID: 18493654; PMCID: PMC2848974.
      View in: PubMed   Mentions: 45     Fields:    Translation:AnimalsCells
    260. The marine lipopeptide somocystinamide A triggers apoptosis via caspase 8. Proc Natl Acad Sci U S A. 2008 Feb 19; 105(7):2313-8. Wrasidlo W, Mielgo A, Torres VA, Barbero S, Stoletov K, Suyama TL, Klemke RL, Gerwick WH, Carson DA, Stupack DG. PMID: 18268346; PMCID: PMC2268133.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
    261. Biosynthetic origin of natural products isolated from marine microorganism-invertebrate assemblages. Proc Natl Acad Sci U S A. 2008 Mar 25; 105(12):4587-94. Simmons TL, Coates RC, Clark BR, Engene N, Gonzalez D, Esquenazi E, Dorrestein PC, Gerwick WH. PMID: 18250337; PMCID: PMC2290810.
      View in: PubMed   Mentions: 79     Fields:    Translation:AnimalsCellsPHPublic Health
    262. Symplocamide A, a potent cytotoxin and chymotrypsin inhibitor from the marine Cyanobacterium Symploca sp. J Nat Prod. 2008 Jan; 71(1):22-7. Linington RG, Edwards DJ, Shuman CF, McPhail KL, Matainaho T, Gerwick WH. PMID: 18163584; PMCID: PMC2832912.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansAnimalsCells
    263. Cloning and biochemical characterization of the hectochlorin biosynthetic gene cluster from the marine cyanobacterium Lyngbya majuscula. J Nat Prod. 2007 Dec; 70(12):1977-86. Ramaswamy AV, Sorrels CM, Gerwick WH. PMID: 18001088.
      View in: PubMed   Mentions: 52     Fields:    Translation:Cells
    264. GNAT-like strategy for polyketide chain initiation. Science. 2007 Nov 09; 318(5852):970-4. Gu L, Geders TW, Wang B, Gerwick WH, Håkansson K, Smith JL, Sherman DH. PMID: 17991863.
      View in: PubMed   Mentions: 50     Fields:    Translation:Cells
    265. Oxo-phytodienoic acid-containing galactolipids in Arabidopsis: jasmonate signaling dependence. Plant Physiol. 2007 Dec; 145(4):1658-69. Kourtchenko O, Andersson MX, Hamberg M, Brunnström A, Göbel C, McPhail KL, Gerwick WH, Feussner I, Ellerström M. PMID: 17951463; PMCID: PMC2151682.
      View in: PubMed   Mentions: 39     Fields:    Translation:AnimalsCells
    266. Crystal structure of the ECH2 catalytic domain of CurF from Lyngbya majuscula. Insights into a decarboxylase involved in polyketide chain beta-branching. J Biol Chem. 2007 Dec 07; 282(49):35954-63. Geders TW, Gu L, Mowers JC, Liu H, Gerwick WH, Håkansson K, Sherman DH, Smith JL. PMID: 17928301.
      View in: PubMed   Mentions: 23     Fields:    Translation:Cells
    267. Hydroxyalkenylresorcinols from Stylogyne turbacensis. J Nat Prod. 2007 Aug; 70(8):1249-52. Jiménez-Romero C, Torres-Mendoza D, Ureña González LD, Ortega-Barría E, McPhail KL, Gerwick WH, Cubilla-Rios L. PMID: 17629327.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    268. Antimalarial linear lipopeptides from a Panamanian strain of the marine cyanobacterium Lyngbya majuscula. J Nat Prod. 2007 Jun; 70(6):984-8. McPhail KL, Correa J, Linington RG, Gonzalez J, Ortega-Barría E, Capson TL, Gerwick WH. PMID: 17441769; PMCID: PMC2745555.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
    269. Venturamides A and B: antimalarial constituents of the panamanian marine Cyanobacterium Oscillatoria sp. J Nat Prod. 2007 Mar; 70(3):397-401. Linington RG, Gonzalez J, Ureña LD, Romero LI, Ortega-Barría E, Gerwick WH. PMID: 17328572.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansAnimalsCells
    270. The genomisotopic approach: a systematic method to isolate products of orphan biosynthetic gene clusters. Chem Biol. 2007 Jan; 14(1):53-63. Gross H, Stockwell VO, Henkels MD, Nowak-Thompson B, Loper JE, Gerwick WH. PMID: 17254952.
      View in: PubMed   Mentions: 91     Fields:    Translation:Cells
    271. Practical total syntheses of epiquinamide enantiomers. Org Lett. 2006 Sep 28; 8(20):4541-3. Suyama TL, Gerwick WH. PMID: 16986945; PMCID: PMC2647512.
      View in: PubMed   Mentions: 7     Fields:    
    272. Oxylipin profiling of the hypersensitive response in Arabidopsis thaliana. Formation of a novel oxo-phytodienoic acid-containing galactolipid, arabidopside E. J Biol Chem. 2006 Oct 20; 281(42):31528-37. Andersson MX, Hamberg M, Kourtchenko O, Brunnström A, McPhail KL, Gerwick WH, Göbel C, Feussner I, Ellerström M. PMID: 16923817.
      View in: PubMed   Mentions: 47     Fields:    Translation:AnimalsCells
    273. Metabolic coupling of dehydration and decarboxylation in the curacin A pathway: functional identification of a mechanistically diverse enzyme pair. J Am Chem Soc. 2006 Jul 19; 128(28):9014-5. Gu L, Jia J, Liu H, Håkansson K, Gerwick WH, Sherman DH. PMID: 16834357.
      View in: PubMed   Mentions: 30     Fields:    Translation:Cells
    274. Characterization of the initial enzymatic steps of barbamide biosynthesis. J Nat Prod. 2006 Jun; 69(6):938-44. Flatt PM, O'Connell SJ, McPhail KL, Zeller G, Willis CL, Sherman DH, Gerwick WH. PMID: 16792414.
      View in: PubMed   Mentions: 28     Fields:    Translation:Cells
    275. Weakly antimalarial flavonol arabinofuranosides from Calycolpus warszewiczianus. J Nat Prod. 2006 May; 69(5):826-8. Torres-Mendoza D, González J, Ortega-Barría E, Heller MV, Capson TL, McPhail K, Gerwick WH, Cubilla-Rios L. PMID: 16724851.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    276. Aurilides B and C, cancer cell toxins from a Papua New Guinea collection of the marine cyanobacterium Lyngbya majuscula. J Nat Prod. 2006 Apr; 69(4):572-5. Han B, Gross H, Goeger DE, Mooberry SL, Gerwick WH. PMID: 16643028.
      View in: PubMed   Mentions: 37     Fields:    Translation:Cells
    277. Lophocladines, bioactive alkaloids from the red alga Lophocladia sp. J Nat Prod. 2006 Apr; 69(4):640-4. Gross H, Goeger DE, Hills P, Mooberry SL, Ballantine DL, Murray TF, Valeriote FA, Gerwick WH. PMID: 16643042; PMCID: PMC2668242.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    278. DNA methyl transferase inhibiting halogenated monoterpenes from the Madagascar red marine alga Portieria hornemannii. J Nat Prod. 2006 Apr; 69(4):576-9. Andrianasolo EH, France D, Cornell-Kennon S, Gerwick WH. PMID: 16643029.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    279. Activity screening of carrier domains within nonribosomal peptide synthetases using complex substrate mixtures and large molecule mass spectrometry. Biochemistry. 2006 Feb 14; 45(6):1537-46. Dorrestein PC, Blackhall J, Straight PD, Fischbach MA, Garneau-Tsodikova S, Edwards DJ, McLaughlin S, Lin M, Gerwick WH, Kolter R, Walsh CT, Kelleher NL. PMID: 16460000; PMCID: PMC2565507.
      View in: PubMed   Mentions: 24     Fields:    Translation:Cells
    280. Minor alkaloids from Guatteria dumetorum with antileishmanial activity. Planta Med. 2006 Feb; 72(3):270-2. Correa JE, Ríos CH, del Rosario Castillo A, Romero LI, Ortega-Barría E, Coley PD, Kursar TA, Heller MV, Gerwick WH, Rios LC. PMID: 16534735.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    281. Neurotoxic meroditerpenoids from the tropical marine brown alga Stypopodium flabelliforme. J Nat Prod. 2005 Jul; 68(7):1022-30. Sabry OM, Andrews S, McPhail KL, Goeger DE, Yokochi A, LePage KT, Murray TF, Gerwick WH. PMID: 16038542.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    282. The wewakpeptins, cyclic depsipeptides from a Papua New Guinea collection of the marine cyanobacterium Lyngbya semiplena. J Org Chem. 2005 Apr 15; 70(8):3133-9. Han B, Goeger D, Maier CS, Gerwick WH. PMID: 15822975.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    283. The neurotoxic lipopeptide kalkitoxin interacts with voltage-sensitive sodium channels in cerebellar granule neurons. Toxicol Lett. 2005 Aug 14; 158(2):133-9. LePage KT, Goeger D, Yokokawa F, Asano T, Shioiri T, Gerwick WH, Murray TF. PMID: 16039402.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    284. Isolation of swinholide A and related glycosylated derivatives from two field collections of marine cyanobacteria. Org Lett. 2005 Mar 31; 7(7):1375-8. Andrianasolo EH, Gross H, Goeger D, Musafija-Girt M, McPhail K, Leal RM, Mooberry SL, Gerwick WH. PMID: 15787510.
      View in: PubMed   Mentions: 47     Fields:    Translation:AnimalsCells
    285. Marine natural products as anticancer drugs. Mol Cancer Ther. 2005 Feb; 4(2):333-42. Simmons TL, Andrianasolo E, McPhail K, Flatt P, Gerwick WH. PMID: 15713904.
      View in: PubMed   Mentions: 164     Fields:    Translation:HumansAnimals
    286. On the use of neuro-2a neuroblastoma cells versus intact neurons in primary culture for neurotoxicity studies. Crit Rev Neurobiol. 2005; 17(1):27-50. LePage KT, Dickey RW, Gerwick WH, Jester EL, Murray TF. PMID: 16307526.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansAnimalsCells
    287. Lyngbyatoxin biosynthesis: sequence of biosynthetic gene cluster and identification of a novel aromatic prenyltransferase. J Am Chem Soc. 2004 Sep 22; 126(37):11432-3. Edwards DJ, Gerwick WH. PMID: 15366877.
      View in: PubMed   Mentions: 64     Fields:    Translation:Cells
    288. Biosynthetic pathway and gene cluster analysis of curacin A, an antitubulin natural product from the tropical marine cyanobacterium Lyngbya majuscula. J Nat Prod. 2004 Aug; 67(8):1356-67. Chang Z, Sitachitta N, Rossi JV, Roberts MA, Flatt PM, Jia J, Sherman DH, Gerwick WH. PMID: 15332855.
      View in: PubMed   Mentions: 107     Fields:    Translation:Cells
    289. Structure and biosynthesis of the jamaicamides, new mixed polyketide-peptide neurotoxins from the marine cyanobacterium Lyngbya majuscula. Chem Biol. 2004 Jun; 11(6):817-33. Edwards DJ, Marquez BL, Nogle LM, McPhail K, Goeger DE, Roberts MA, Gerwick WH. PMID: 15217615.
      View in: PubMed   Mentions: 189     Fields:    Translation:HumansAnimalsCells
    290. Peyssonenynes a and B, novel enediyne oxylipins with DNA methyl transferase inhibitory activity from the red marine alga peyssonneliacaulifera. J Nat Prod. 2004 Jun; 67(6):1010-3. McPhail KL, France D, Cornell-Kennon S, Gerwick WH. PMID: 15217284.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    291. Characterization of the preferred stereochemistry for the neuropharmacologic actions of antillatoxin. J Nat Prod. 2004 Apr; 67(4):559-68. Li WI, Marquez BL, Okino T, Yokokawa F, Shioiri T, Gerwick WH, Murray TF. PMID: 15104484.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    292. Evaluation of the efficiency of three different solvent systems to extract triterpene saponins from roots of Panax quinquefolius using high-performance liquid chromatography. J Agric Food Chem. 2004 Mar 24; 52(6):1546-50. Gafner S, Bergeron C, McCollom MM, Cooper LM, McPhail KL, Gerwick WH, Angerhofer CK. PMID: 15030209.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    293. Secondary metabolites from marine cyanobacteria and algae inhibit LFA-1/ICAM-1 mediated cell adhesion. Planta Med. 2004 Feb; 70(2):127-31. Takamatsu S, Nagle DG, Gerwick WH. PMID: 14994189.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    294. Semiplenamides A-G, fatty acid amides from a Papua New Guinea collection of the marine cyanobacterium Lyngbya semiplena. J Nat Prod. 2003 Oct; 66(10):1364-8. Han B, McPhail KL, Ligresti A, Di Marzo V, Gerwick WH. PMID: 14575438.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    295. The guineamides, novel cyclic depsipeptides from a Papua New Guinea collection of the marine cyanobacterium Lyngbya majuscula. J Nat Prod. 2003 Jun; 66(6):764-71. Tan LT, Sitachitta N, Gerwick WH. PMID: 12828459.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    296. Marine natural products as novel antioxidant prototypes. J Nat Prod. 2003 May; 66(5):605-8. Takamatsu S, Hodges TW, Rajbhandari I, Gerwick WH, Hamann MT, Nagle DG. PMID: 12762791; PMCID: PMC4969048.
      View in: PubMed   Mentions: 55     Fields:    Translation:AnimalsCells
    297. Diverse secondary metabolites from a Puerto Rican collection of Lyngbyamajuscula. J Nat Prod. 2003 Feb; 66(2):217-20. Nogle LM, Gerwick WH. PMID: 12608852.
      View in: PubMed   Mentions: 9     Fields:    Translation:Cells
    298. Wewakazole, a novel cyclic dodecapeptide from a Papua New Guinea Lyngbya majuscula. Org Lett. 2003 Jan 09; 5(1):3-6. Nogle LM, Marquez BL, Gerwick WH. PMID: 12509876.
      View in: PubMed   Mentions: 12     Fields:    Translation:Cells
    299. Three new malyngamides from a Papua New Guinea collection of the marine cyanobacterium Lyngbya majuscula. J Nat Prod. 2003 Jan; 66(1):132-5. McPhail KL, Gerwick WH. PMID: 12542362.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    300. The identification and characterization of the marine natural product scytonemin as a novel antiproliferative pharmacophore. J Pharmacol Exp Ther. 2002 Nov; 303(2):858-66. Stevenson CS, Capper EA, Roshak AK, Marquez B, Eichman C, Jackson JR, Mattern M, Gerwick WH, Jacobs RS, Marshall LA. PMID: 12388673.
      View in: PubMed   Mentions: 51     Fields:    Translation:HumansCells
    301. Structure and absolute stereochemistry of hectochlorin, a potent stimulator of actin assembly. J Nat Prod. 2002 Jun; 65(6):866-71. Marquez BL, Watts KS, Yokochi A, Roberts MA, Verdier-Pinard P, Jimenez JI, Hamel E, Scheuer PJ, Gerwick WH. PMID: 12088429.
      View in: PubMed   Mentions: 48     Fields:    Translation:AnimalsCells
    302. Lyngbouilloside, a novel glycosidic macrolide from the marine cyanobacterium Lyngbya bouillonii. J Nat Prod. 2002 Jun; 65(6):925-8. Tan LT, Márquez BL, Gerwick WH. PMID: 12088441.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    303. Somocystinamide A, a novel cytotoxic disulfide dimer from a Fijian marine cyanobacterial mixed assemblage. Org Lett. 2002 Apr 04; 4(7):1095-8. Nogle LM, Gerwick WH. PMID: 11922791.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    304. Scytonemin--a marine natural product inhibitor of kinases key in hyperproliferative inflammatory diseases. Inflamm Res. 2002 Feb; 51(2):112-4. Stevenson CS, Capper EA, Roshak AK, Marquez B, Grace K, Gerwick WH, Jacobs RS, Marshall LA. PMID: 11926312.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimalsCells
    305. Isolation of four new cyclic depsipeptides, antanapeptins A-D, and dolastatin 16 from a Madagascan collection of Lyngbya majuscula. J Nat Prod. 2002 Jan; 65(1):21-4. Nogle LM, Gerwick WH. PMID: 11809058.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    306. Vidalenolone, a novel phenolic metabolite from the tropical red alga Vidalia sp. J Nat Prod. 2002 Jan; 65(1):51-3. Yoo HD, Ketchum SO, France D, Bair K, Gerwick WH. PMID: 11809064.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    307. Synthesis of the marine natural product barbamide. Chem Commun (Camb). 2001 Oct 07; (19):1934-5. Nguyen VA, Willis CL, Gerwick WH. PMID: 12240226.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    308. Antillatoxin is a marine cyanobacterial toxin that potently activates voltage-gated sodium channels. Proc Natl Acad Sci U S A. 2001 Jun 19; 98(13):7599-604. Li WI, Berman FW, Okino T, Yokokawa F, Shioiri T, Gerwick WH, Murray TF. PMID: 11416227; PMCID: PMC34714.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    309. Somamides A and B, two new depsipeptide analogues of dolastatin 13 from a Fijian cyanobacterial assemblage of Lyngbya majuscula and Schizothrix species. J Nat Prod. 2001 Jun; 64(6):716-9. Nogle LM, Williamson RT, Gerwick WH. PMID: 11421730.
      View in: PubMed   Mentions: 21     Fields:    Translation:Cells
    310. Nitrogen-containing metabolites from marine cyanobacteria. Alkaloids Chem Biol. 2001; 57:75-184. Gerwick WH, Tan LT, Sitachitta N. PMID: 11705123.
      View in: PubMed   Mentions: 56     Fields:    Translation:CellsPHPublic Health
    311. Lyngbyabellin B, a toxic and antifungal secondary metabolite from the marine cyanobacterium Lyngbya majuscula. J Nat Prod. 2000 Oct; 63(10):1440-3. Milligan KE, Marquez BL, Williamson RT, Gerwick WH. PMID: 11076574.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    312. Hermitamides A and B, toxic malyngamide-type natural products from the marine cyanobacterium Lyngbya majuscula. J Nat Prod. 2000 Jul; 63(7):952-5. Tan LT, Okino T, Gerwick WH. PMID: 10924172.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    313. Two new malyngamides from a Madagascan Lyngbya majuscula. J Nat Prod. 2000 Jul; 63(7):965-8. Milligan KE, Márquez B, Williamson RT, Davies-Coleman M, Gerwick WH. PMID: 10924175.
      View in: PubMed   Mentions: 10     Fields:    Translation:Cells
    314. Application of the BIRD sandwich for the rapid and accurate determination of (1)H-(1)H NMR coupling constants in higher order spin systems. J Nat Prod. 2000 Jun; 63(6):876-8. Williamson RT, Carney JR, Gerwick WH. PMID: 10869227.
      View in: PubMed   Mentions:    Fields:    
    315. New diffusion-edited NMR experiments to expedite the dereplication of known compounds from natural product mixtures. Org Lett. 2000 Feb 10; 2(3):289-92. Williamson RT, Chapin EL, Carr AW, Gilbert JR, Graupner PR, Lewer P, McKamey P, Carney JR, Gerwick WH. PMID: 10814304.
      View in: PubMed   Mentions: 6     Fields:    Translation:Cells
    316. Yanucamides A and B, two new depsipeptides from an assemblage of the marine cyanobacteria Lyngbya majuscula and Schizothrix species. J Nat Prod. 2000 Feb; 63(2):197-200. Sitachitta N, Williamson RT, Gerwick WH. PMID: 10691708.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    317. cis,cis- and trans,trans-ceratospongamide, new bioactive cyclic heptapeptides from the Indonesian red alga Ceratodictyon spongiosum and symbiotic sponge Sigmadocia symbiotica. J Org Chem. 2000 Jan 28; 65(2):419-25. Tan LT, Williamson RT, Gerwick WH, Watts KS, McGough K, Jacobs R. PMID: 10813950.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    318. 5-Lipoxygenase-derived oxylipins from the red alga Rhodymenia pertusa. Phytochemistry. 2000 Jan; 53(1):129-33. Jiang ZD, Ketchum SO, Gerwick WH. PMID: 10656420.
      View in: PubMed   Mentions: 11     Fields:    Translation:Animals
    319. Antillatoxin and kalkitoxin, ichthyotoxins from the tropical cyanobacterium Lyngbya majuscula, induce distinct temporal patterns of NMDA receptor-mediated neurotoxicity. Toxicon. 1999 Nov; 37(11):1645-8. Berman FW, Gerwick WH, Murray TF. PMID: 10482399.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    320. Biosynthesis of radiolabeled curacin A and its rapid and apparently irreversible binding to the colchicine site of tubulin. Arch Biochem Biophys. 1999 Oct 01; 370(1):51-8. Verdier-Pinard P, Sitachitta N, Rossi JV, Sackett DL, Gerwick WH, Hamel E. PMID: 10496976.
      View in: PubMed   Mentions: 7     Fields:    Translation:Cells
    321. Tanikolide, a toxic and antifungal lactone from the marine cyanobacterium Lyngbya majuscula. J Nat Prod. 1999 Sep; 62(9):1333-5. Singh IP, Milligan KE, Gerwick WH. PMID: 10514329.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    322. Biogenesis and biological function of marine algal oxylipins. Adv Exp Med Biol. 1999; 447:211-8. Gerwick WH, Roberts MA, Vulpanovici A, Ballantine DL. PMID: 10086197.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    323. Curacin D, an antimitotic agent from the marine cyanobacterium Lyngbya majuscula. Phytochemistry. 1998 Dec; 49(8):2387-9. Márquez B, Verdier-Pinard P, Hamel E, Gerwick WH. PMID: 9887531.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    324. Arachidonoylserotonin and other novel inhibitors of fatty acid amide hydrolase. Biochem Biophys Res Commun. 1998 Jul 30; 248(3):515-22. Bisogno T, Melck D, De Petrocellis L, Gretskaya NM, Bezuglov VV, Sitachitta N, Gerwick WH, Di Marzo V. PMID: 9703957.
      View in: PubMed   Mentions: 50     Fields:    Translation:AnimalsCells
    325. Kalkipyrone, a toxic gamma-pyrone from an assemblage of the marine cyanobacteria Lyngbya majuscula and Tolypothrix sp. J Nat Prod. 1998 May; 61(5):677-80. Graber MA, Gerwick WH. PMID: 9599278.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    326. Grenadadiene and grenadamide, cyclopropyl-containing fatty acid metabolites from the marine cyanobacterium Lyngbya majuscula. J Nat Prod. 1998 May; 61(5):681-4. Sitachitta N, Gerwick WH. PMID: 9599279.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    327. Carmabins A and B, new lipopeptides from the Caribbean cyanobacterium Lyngbya majuscula. J Nat Prod. 1998 Apr; 61(4):529-33. Hooper GJ, Orjala J, Schatzman RC, Gerwick WH. PMID: 9584405.
      View in: PubMed   Mentions: 27     Fields:    Translation:Cells
    328. Structure-activity analysis of the interaction of curacin A, the potent colchicine site antimitotic agent, with tubulin and effects of analogs on the growth of MCF-7 breast cancer cells. Mol Pharmacol. 1998 Jan; 53(1):62-76. Verdier-Pinard P, Lai JY, Yoo HD, Yu J, Marquez B, Nagle DG, Nambu M, White JD, Falck JR, Gerwick WH, Day BW, Hamel E. PMID: 9443933.
      View in: PubMed   Mentions: 112     Fields:    Translation:HumansAnimalsCells
    329. Two quinoline alkaloids from the Caribbean cyanobacterium Lyngbya majuscula. Phytochemistry. 1997 Jul; 45(5):1087-90. Orjala J, Gerwick WH. PMID: 9214778.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    330. Characterization of the substrate binding site of polyenoic fatty acid isomerase, a novel enzyme from the marine alga Ptilota filicina. Biochemistry. 1997 Mar 11; 36(10):2985-92. Wise ML, Rossi J, Gerwick WH. PMID: 9062129.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    331. Novel oxylipins from the temperate red alga Polyneura latissima: evidence for an arachidonate 9(S)-lipoxygenase. Lipids. 1997 Mar; 32(3):231-5. Jiang ZD, Gerwick WH. PMID: 9076659.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    332. Biosynthesis and cannabinoid receptor affinity of the novel eicosanoid, conjugated triene anandamide. Adv Exp Med Biol. 1997; 407:329-34. Gerwick WH, Wise ML, Soderstrom K, Murray TF. PMID: 9321972.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    333. Discovery of novel cannabinoid receptor ligands from diverse marine organisms. Adv Exp Med Biol. 1997; 433:73-7. Soderstrom K, Murray TF, Yoo HD, Ketchum S, Milligan K, Gerwick W, Ortega MJ, Salva J. PMID: 9561107.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    334. Epoxy allylic carbocations as conceptual intermediates in the biogenesis of diverse marine oxylipins. Lipids. 1996 Dec; 31(12):1215-31. Gerwick WH. PMID: 8972454.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    335. Barbamide, a chlorinated metabolite with molluscicidal activity from the Caribbean cyanobacterium Lyngbya majuscula. J Nat Prod. 1996 Apr; 59(4):427-30. Orjala J, Gerwick WH. PMID: 8699186.
      View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
    336. Synthesis and cannabinoid receptor binding activity of conjugated triene anandamide, a novel eicosanoid. Experientia. 1996 Jan 16; 52(1):88-92. Wise ML, Soderstrom K, Murray TF, Gerwick WH. PMID: 8575565.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    337. Characterization of the interaction of the marine cyanobacterial natural product curacin A with the colchicine site of tubulin and initial structure-activity studies with analogues. Mol Pharmacol. 1995 Sep; 48(3):523-31. Blokhin AV, Yoo HD, Geralds RS, Nagle DG, Gerwick WH, Hamel E. PMID: 7565634.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    338. Structure and biosynthesis of novel conjugated polyene fatty acids from the marine green alga Anadyomene stellata. Lipids. 1995 Jul; 30(7):583-9. Mikhailova MV, Bemis DL, Wise ML, Gerwick WH, Norris JN, Jacobs RS. PMID: 7564911.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    339. Malyngamide H, an ichthyotoxic amide possessing a new carbon skeleton from the Caribbean cyanobacterium Lyngbya majuscula. J Nat Prod. 1995 May; 58(5):764-8. Orjala J, Nagle D, Gerwick WH. PMID: 7623050.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    340. Isolation of a cyclic carbonate, a gamma-butyrolactone, and a new indole derivative from the marine cyanobacterium Lyngbya majuscula. J Nat Prod. 1995 Apr; 58(4):586-9. Todd JS, Gerwick WH. PMID: 7623035.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    341. Biosynthesis of conjugated triene-containing fatty acids by a novel isomerase from the red marine alga Ptilota filicina. Biochemistry. 1994 Dec 27; 33(51):15223-32. Wise ML, Hamberg M, Gerwick WH. PMID: 7803384.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    342. Absolute stereochemistry of neohalicholactone from the brown alga Laminaria sinclairii. J Nat Prod. 1994 Dec; 57(12):1717-9. Proteau PJ, Rossi JV, Gerwick WH. PMID: 7714540.
      View in: PubMed   Mentions: 3     Fields:    
    343. Isorawsonol and related IMP dehydrogenase inhibitors from the tropical green alga Avrainvillea rawsonii. J Nat Prod. 1994 Jul; 57(7):947-52. Chen JL, Gerwick WH, Schatzman R, Laney M. PMID: 7964790.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    344. Structure of malhamensilipin A, an inhibitor of protein tyrosine kinase, from the cultured chrysophyte Poterioochromonas malhamensis. J Nat Prod. 1994 Apr; 57(4):524-7. Chen JL, Proteau PJ, Roberts MA, Gerwick WH, Slate DL, Lee RH. PMID: 8021653.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    345. Structure and biosynthesis of marine algal oxylipins. Biochim Biophys Acta. 1994 Mar 24; 1211(3):243-55. Gerwick WH. PMID: 8130256.
      View in: PubMed   Mentions: 18     Fields:    Translation:Animals
    346. The absolute configuration of ecklonialactones A, B, and E, novel oxylipins from brown algae of the genera Ecklonia and Egregia. J Nat Prod. 1994 Jan; 57(1):171-4. Todd JS, Proteau PJ, Gerwick WH. PMID: 8158161.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
    347. The structure of scytonemin, an ultraviolet sunscreen pigment from the sheaths of cyanobacteria. Experientia. 1993 Sep 15; 49(9):825-9. Proteau PJ, Gerwick WH, Garcia-Pichel F, Castenholz R. PMID: 8405307.
      View in: PubMed   Mentions: 67     Fields:    Translation:Cells
    348. Divinyl ethers and hydroxy fatty acids from three species of Laminaria (brown algae). Lipids. 1993 Sep; 28(9):783-7. Proteau PJ, Gerwick WH. PMID: 8231653.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    349. Biosynthesis of vicinal dihydroxy fatty acids in the red alga Gracilariopsis lemaneiformis: identification of a sodium-dependent 12-lipoxygenase and a hydroperoxide isomerase. Arch Biochem Biophys. 1993 Aug 15; 305(1):115-22. Hamberg M, Gerwick WH. PMID: 8342944.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    350. Unprecedented oxylipins from the marine green alga Acrosiphonia coalita. J Nat Prod. 1993 Feb; 56(2):245-59. Bernart MW, Whatley GG, Gerwick WH. PMID: 8463797.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    351. New glycosphingolipids from the marine sponge Halichondria panicea. J Nat Prod. 1992 Jul; 55(7):1013-7. Nagle DG, McClatchey WC, Gerwick WH. PMID: 1402953.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    352. Cell-free biosynthesis and source of hydroxyl groups in (12R,13S)-dihydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoic acid, a novel eicosanoid from the marine alga Gracilariopsis lemaneiformis. J Nat Prod. 1991 Nov-Dec; 54(6):1619-24. Moghaddam MF, Gerwick WH. PMID: 1667411.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    353. Oxylipin metabolism in the red alga Gracilariopsis lemaneiformis: mechanism of formation of vicinal dihydroxy fatty acids. Arch Biochem Biophys. 1991 Nov 01; 290(2):436-44. Gerwick WH, Moghaddam M, Hamberg M. PMID: 1929410.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    354. An aldehyde-containing galactolipid from the red alga Gracilariopsis lemaneiformis. Lipids. 1991 Nov; 26(11):960-3. Jiang ZD, Gerwick WH. PMID: 1805099.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    355. Novel pyrroles from the Oregon red alga Gracilariopsis lemaneiformis. J Nat Prod. 1991 Mar-Apr; 54(2):403-7. Jiang ZD, Gerwick WH. PMID: 1919587.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    356. Discovery of the mammalian insulin release modulator, hepoxilin B3, from the tropical red algae Platysiphonia miniata and Cottoniella filamentosa. J Biol Chem. 1990 Apr 15; 265(11):6126-30. Moghaddam MF, Gerwick WH, Ballantine DL. PMID: 2180942.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    357. Three new and bioactive icosanoids from the temperate red marine alga Farlowia mollis. Lipids. 1989 Apr; 24(4):256-60. Solem ML, Jiang ZD, Gerwick WH. PMID: 2547132.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    358. 6-Desmethoxyhormothamnione, a new cytotoxic styrylchromone from the marine cryptophyte Chrysophaeum taylori. J Nat Prod. 1989 Mar-Apr; 52(2):252-6. Gerwick WH. PMID: 2746254.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    359. Novel cytotoxic peptides from the tropical marine cyanobacterium Hormothamnion enteromorphoides. 1. Discovery, isolation and initial chemical and biological characterization of the hormothamnins from wild and cultured material. Experientia. 1989 Feb 15; 45(2):115-21. Gerwick WH, Mrozek C, Moghaddam MF, Agarwal SK. PMID: 2493387.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    360. Discovery of 12-(S)-hydroxy-5,8,10,14-icosatetraenoic acid [12-(S)-HETE] in the tropical red alga Platysiphonia miniata. Prostaglandins. 1989 Feb; 37(2):303-8. Moghaddam MF, Gerwick WH, Ballantine DL. PMID: 2727309.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    361. Aplysia sea hare assimilation of secondary metabolites from brown seaweed,Stypopodium zonale. J Chem Ecol. 1989 Feb; 15(2):677-83. Gerwick WH, Whatley G. PMID: 24271808.
      View in: PubMed   Mentions: 1     Fields:    
    362. Precipitate analysis from an indwelling total parenteral nutrition catheter. JPEN J Parenter Enteral Nutr. 1988 Jan-Feb; 12(1):88-92. Stennett DJ, Gerwick WH, Egging PK, Christensen JM. PMID: 3125364.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    363. 5'-Hydroxyisoavrainvilleol, a new diphenylmethane derivative from the tropical green alga Avrainvillea nigricans. J Nat Prod. 1987 May-Jun; 50(3):368-74. Colon M, Guevara P, Gerwick WH, Ballantine D. PMID: 3668556.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    364. Two new icosapentaenoic acids from the temperate red seaweed Ptilota filicina J. Agardh. Lipids. 1987 Mar; 22(3):190-4. Lopez A, Gerwick WH. PMID: 3033420.
      View in: PubMed   Mentions: 18     Fields:    Translation:Animals
    William's Networks
    Concepts (901)
    Derived automatically from this person's publications.
    _
    Co-Authors (69)
    People in Profiles who have published with this person.
    _
    Similar People (60)
    People who share similar concepts with this person.
    _
    Same Department
    Search Department
    _