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Palmer Taylor

TitleProfessor
InstitutionUniversity of California San Diego
DepartmentSchool of Pharmacy and Pharmaceutical Science
Address9500 Gilman Drive #0650
La Jolla CA 92093
Phone858-534-1366
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    Collapse Biography 
    Collapse Education and Training
    Ph.D.University of Wisconsin

    Collapse Overview 

    Collapse Research 
    Collapse Research Activities and Funding
    Optimization of nonpyridinium oximes for BChE hydrolysis of OPs in plasma
    NIH/NINDS R21NS072086Sep 30, 2010 - Aug 31, 2013
    Role: Principal Investigator
    Predoctoral Research Training in Maternal and Pediatric Pharmacology
    NIH/NICHD T35HD064385Apr 1, 2010 - Jul 31, 2022
    Role: Principal Investigator
    Oxime-Assisted Catalysis of Organophosphates and Reactivation of AChE
    NIH/NINDS U01NS058046Sep 30, 2006 - Oct 31, 2012
    Role: Principal Investigator
    Nicotinic Receptor Template-guided Drug Design
    NIH/NIDA U01DA019372Sep 30, 2004 - Jun 30, 2010
    Role: Principal Investigator
    FACILITIES CONSTRUCTION CENTERALIZED PHARMCOGENOMICS
    NIH/NCRR C06RR017309Sep 15, 2003 - Sep 14, 2005
    Role: Principal Investigator
    DETECTION AND MODELS OF TOXICANT EXPOSURE
    NIH/NIEHS P42ES010337Jul 1, 2000 - Mar 31, 2022
    Role: Co-Investigator
    NATIONAL BIOMEDICAL COMPUTATION RESOURCE
    NIH P41RR008605Apr 15, 1994 - Apr 30, 2014
    Role: Co-Investigator
    MOLECULAR PHARMACOLOGY
    NIH/NIGMS R13GM042914Jun 1, 1989 - May 31, 1990
    Role: Principal Investigator
    IVEM and Image Analysis Resource
    NIH/NCRR P41RR004050Dec 12, 1988 - Mar 31, 2014
    Role: Co-Investigator
    GENETIC AND RECEPTOR MECHANISMS IN HYPERTENSION
    NIH/NHLBI P01HL035018Mar 1, 1986 - Dec 31, 2009
    Role: Co-Investigator
    RECEPTOR REGULATION OF CA IN VASCULAR SMOOTH MUSCLE
    NIH/NIGMS R01GM036237Feb 1, 1986 - Jan 31, 1992
    Role: Principal Investigator
    Graduate Training in Cellular and Molecular Pharmacology
    NIH/NIGMS T32GM007752Jul 1, 1979 - Jun 30, 2019
    Role: Principal Investigator
    PHARMACOLOGY OF MEMBRANE ASSOCIATION RECEPTORS
    NIH/NIGMS R01GM024337Jul 1, 1977 - Mar 31, 1995
    Role: Principal Investigator
    Kinetics of Drug Macromolecule Complex Formation
    NIH/NIGMS R01GM018360Jan 1, 1975 - Nov 30, 2014
    Role: Principal Investigator
    KINETICS OF DRUG MACROMOLECULE COMPLEX FORMATION
    NIH/NIGMS R37GM018360Jan 1, 1975 - Dec 31, 2009
    Role: Principal Investigator

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    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Taylor P, De Jaco A, Comoletti D, Miller M, Camp S. Cholinesterase confabs and cousins: approaching forty years. Chem Biol Interact. 2013 Mar 25; 203(1):10-3. PMID: 23085121; PMCID: PMC3618580.
    2. Taylor P. Defining the determinants of nicotine selectivity. Proc Natl Acad Sci U S A. 2010 Jul 27; 107(30):13195-6. PMID: 20643924; PMCID: PMC2922162.
    3. Taylor P. From Split to Sibenik: the tortuous pathway in the cholinesterase field. Chem Biol Interact. 2010 Sep 06; 187(1-3):3-9. PMID: 20493179; PMCID: PMC3000743.
    4. Utsintong M, Talley TT, Taylor PW, Olson AJ, Vajragupta O. Virtual screening against alpha-cobratoxin. J Biomol Screen. 2009 Oct; 14(9):1109-18. PMID: 19734437; PMCID: PMC3191909.
    5. Taylor P, Reiner E, Kovarik Z, Radic Z. Application of recombinant DNA methods for production of cholinesterases as organophosphate antidotes and detectors. Arh Hig Rada Toksikol. 2007 Sep; 58(3):339-45. PMID: 17913689.
      View in: PubMed
    6. Taylor P, Talley TT, Radic' Z, Hansen SB, Hibbs RE, Shi J. Structure-guided drug design: conferring selectivity among neuronal nicotinic receptor and acetylcholine-binding protein subtypes. Biochem Pharmacol. 2007 Oct 15; 74(8):1164-71. PMID: 17826748; PMCID: PMC3341175.
    7. Taylor P, Kovarik Z, Reiner E, Radic Z. Acetylcholinesterase: converting a vulnerable target to a template for antidotes and detection of inhibitor exposure. Toxicology. 2007 Apr 20; 233(1-3):70-8. PMID: 17196318; PMCID: PMC3279330.
    8. Taylor P, Hansen SB, Talley TT, Hibbs RE, Radic Z. Contemporary paradigms for cholinergic ligand design guided by biological structure. Bioorg Med Chem Lett. 2004 Apr 19; 14(8):1875-7. PMID: 15050619; PMCID: PMC3191913.
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