George Liu

Title(s)Professor, Pediatrics
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
Emailgyliu@ucsd.edu
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    Collapse Overview 
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    Collapse Research 
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    Eliminating Acne Through Photo-Inactivation Catalase
    NIH R41AR079349Sep 24, 2021 - Aug 31, 2022
    Role: Co-Principal Investigator
    Staphylococcus aureus interference with IsdB vaccination
    NIH R01AI144694Sep 18, 2019 - Aug 31, 2024
    Role: Principal Investigator
    Pathogenic and protective roles of strain-specific P. acnes hyaluronidases in acne
    NIH R01AI141401Jul 18, 2019 - Jun 30, 2024
    Role: Co-Principal Investigator
    Impact of P. acnes hyaluronidases on acne pathogenesis
    NIH R21AI138053Jun 1, 2018 - May 31, 2020
    Role: Principal Investigator
    Generating protective immunity to Staphylococcus aureus
    NIH R01AI127406Jun 26, 2017 - May 31, 2022
    Role: Co-Principal Investigator
    Nicotinamide-An Immune-Boosting Agent to Combat Antibiotic-Resistant Pathogens
    NIH R21AI112812Jul 4, 2014 - Jun 30, 2016
    Role: Principal Investigator
    Bacterial Manipulation of Host Hyaluronan Degradation for Immune Evasion
    NIH R21AI103839May 15, 2013 - Apr 30, 2015
    Role: Principal Investigator
    Impact of Antibiotics and PBP2a on the Immunopathology of MRSA pneumonia
    NIH R21AI097741Jul 1, 2012 - Jun 30, 2014
    Role: Principal Investigator
    Antioxidant-based mechanisms used by staphyloccocus aureus to evade host defenses
    NIH R01AI074832Sep 15, 2007 - Aug 31, 2012
    Role: Principal Investigator

    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Pathobiont-driven antibody sialylation through IL-10 undermines vaccination. J Clin Invest. 2024 Dec 16; 134(24). Tsai CM, Hajam IA, Caldera JR, Chiang AW, Gonzalez C, Du X, Choudhruy B, Li H, Suzuki E, Askarian F, Clark T, Lin B, Wierzbicki IH, Riestra AM, Conrad DJ, Gonzalez DJ, Nizet V, Lewis NE, Liu GY. PMID: 39680460; PMCID: PMC11645145.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCellsPHPublic Health
    2. Pathobiont-induced suppressive immune imprints thwart T cell vaccine responses. Nat Commun. 2024 Dec 16; 15(1):10335. Hajam IA, Tsai CM, Gonzalez C, Caldera JR, Lázaro Díez M, Du X, Aralar A, Lin B, Duong W, Liu GY. PMID: 39681568; PMCID: PMC11649901.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCellsPHPublic Health
    3. Effective drug design screening in bacterial glycolytic enzymes via targeting alternative allosteric sites. Arch Biochem Biophys. 2024 Dec; 762:110190. Turkmenoglu I, Kurtulus G, Sesal C, Kurkcuoglu O, Ayyildiz M, Celiker S, Ozhelvaci F, Du X, Liu GY, Arditi M, Akten ED. PMID: 39486564.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    4. Glycan-specific IgM is critical for human immunity to Staphylococcus aureus. Cell Rep Med. 2024 Sep 17; 5(9):101734. Hendriks A, Kerkman PF, Varkila MRJ, Haitsma Mulier JLG, Ali S, Ten Doesschate T, van der Vaart TW, de Haas CJC, Aerts PC, Cremer OL, Bonten MJM, Nizet V, Liu GY, Codée JDC, Rooijakkers SHM, van Strijp JAG, van Sorge NM. PMID: 39293400; PMCID: PMC11525025.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    5. Comparative transcriptome analysis of acne vulgaris, rosacea, and hidradenitis suppurativa supports high-dose dietary zinc as a therapeutic agent. Exp Dermatol. 2024 Jul; 33(7):e15145. Li L, Hajam I, McGee JS, Tang Z, Zhang Y, Badey N, Mintzer E, Zhang Z, Liu GY, Church GM, Wang Y. PMID: 39046322; PMCID: PMC11299850.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    6. Linking S. aureus Immune Evasion Mechanisms to Staphylococcal Vaccine Failures. Antibiotics (Basel). 2024 Apr 30; 13(5). Hajam IA, Liu GY. PMID: 38786139; PMCID: PMC11117348.
      View in: PubMed   Mentions: 1  
    7. The characteristics of pre-existing humoral imprint determine efficacy of S. aureus vaccines and support alternative vaccine approaches. Cell Rep Med. 2024 01 16; 5(1):101360. Caldera JR, Tsai CM, Trieu D, Gonzalez C, Hajam IA, Du X, Lin B, Liu GY. PMID: 38232694; PMCID: PMC10829788.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    8. TLR4 sensing of IsdB of Staphylococcus aureus induces a proinflammatory cytokine response via the NLRP3-caspase-1 inflammasome cascade. mBio. 2024 Jan 16; 15(1):e0022523. Gonzalez JJI, Hossain MF, Neef J, Zwack EE, Tsai C-M, Raafat D, Fechtner K, Herzog L, Kohler TP, Schlüter R, Reder A, Holtfreter S, Liu GY, Hammerschmidt S, Völker U, Torres VJ, van Dijl JM, Lillig CH, Bröker BM, Darisipudi MN. PMID: 38112465; PMCID: PMC10790753.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    9. Functional divergence of a bacterial enzyme promotes healthy or acneic skin. Nat Commun. 2023 Dec 05; 14(1):8061. Hajam IA, Katiki M, McNally R, Lázaro-Díez M, Kolar S, Chatterjee A, Gonzalez C, Paulchakrabarti M, Choudhury B, Caldera JR, Desmond T, Tsai CM, Du X, Li H, Murali R, Liu GY. PMID: 38052825; PMCID: PMC10697930.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    10. Comparative Transcriptome Analysis of Acne vulgaris, Rosacea, and Hidradenitis Suppurativa Supports High Dose Dietary Zinc as a Therapeutic Agent. medRxiv. 2023 Dec 04. Li L, Hajam I, McGee JS, Tang Z, Zhang Y, Badey N, Mintzer E, Zhang Z, Liu GY, Church GM, Wang Y. PMID: 38076983; PMCID: PMC10705630.
      View in: PubMed   Mentions:
    11. Immunization with lytic polysaccharide monooxygenase CbpD induces protective immunity against Pseudomonas aeruginosa pneumonia. Proc Natl Acad Sci U S A. 2023 07 25; 120(30):e2301538120. Askarian F, Tsai CM, Cordara G, Zurich RH, Bjånes E, Golten O, Vinther Sørensen H, Kousha A, Meier A, Chikwati E, Bruun JA, Ludviksen JA, Choudhury B, Trieu D, Davis S, Edvardsen PKT, Mollnes TE, Liu GY, Krengel U, Conrad DJ, Vaaje-Kolstad G, Nizet V. PMID: 37459522; PMCID: PMC10372616.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    12. Toward an effective Staphylococcus vaccine: why have candidates failed and what is the next step? Expert Rev Vaccines. 2023 Jan-Dec; 22(1):207-209. Tsai CM, Caldera J, Hajam IA, Liu GY. PMID: 36765453; PMCID: PMC9972957.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    13. Transfer of antibiotics and their metabolites in human milk: Implications for infant health and microbiota. Pharmacotherapy. 2023 05; 43(5):442-451. Thomas SP, Denizer E, Zuffa S, Best BM, Bode L, Chambers CD, Dorrestein PC, Liu GY, Momper JD, Nizet V, Tsunoda SM, Tremoulet AH. PMID: 36181712; PMCID: PMC10763576.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    14. Non-protective immune imprint underlies failure of Staphylococcus aureus IsdB vaccine. Cell Host Microbe. 2022 08 10; 30(8):1163-1172.e6. Tsai CM, Caldera JR, Hajam IA, Chiang AWT, Tsai CH, Li H, Díez ML, Gonzalez C, Trieu D, Martins GA, Underhill DM, Arditi M, Lewis NE, Liu GY. PMID: 35803276; PMCID: PMC9378590.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    15. Photoinactivation of catalase sensitizes a wide range of bacteria to ROS-producing agents and immune cells. JCI Insight. 2022 05 23; 7(10). Dong PT, Jusuf S, Hui J, Zhan Y, Zhu Y, Liu GY, Cheng JX. PMID: 35446788; PMCID: PMC9220836.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    16. Integrating complex host-pathogen immune environments into S. aureus vaccine studies. Cell Chem Biol. 2022 05 19; 29(5):730-740. Tsai CM, Hajam IA, Caldera JR, Liu GY. PMID: 35594849; PMCID: PMC9179946.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    17. Anti-Inflammatory Properties of Plasma from Children with Short Bowel Syndrome. Pathogens. 2021 Aug 13; 10(8). Hajam IA, Ali F, Young J, Garcia MA, Cannavino C, Ramchandar N, Liu GY. PMID: 34451485; PMCID: PMC8400962.
      View in: PubMed   Mentions: 2  
    18. Use of Metagenomic Next-Generation Sequencing to Identify Pathogens in Pediatric Osteoarticular Infections. Open Forum Infect Dis. 2021 Jul; 8(7):ofab346. Ramchandar N, Burns J, Coufal NG, Pennock A, Briggs B, Stinnett R, Bradley J, Arnold J, Liu GY, Pring M, Upasani VV, Rickert K, Dimmock D, Chiu C, Farnaes L, Cannavino C. PMID: 34322569; PMCID: PMC8314938.
      View in: PubMed   Mentions: 11  
    19. Adoptive Transfer of Serum Samples From Children With Invasive Staphylococcal Infection and Protection Against Staphylococcus aureus Sepsis. J Infect Dis. 2021 04 08; 223(7):1222-1231. Tsai CM, Soper N, Bennett M, Fallon JK, Michell AR, Alter G, Liu GY, Thomsen I. PMID: 32990305; PMCID: PMC8030728.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    20. Granadaene Photobleaching Reduces the Virulence and Increases Antimicrobial Susceptibility of Streptococcus agalactiae. Photochem Photobiol. 2021 07; 97(4):816-825. Jusuf S, Dong PT, Hui J, Ulloa ER, Liu GY, Cheng JX. PMID: 33502005; PMCID: PMC8277675.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    21. Immune-Based Anti-Staphylococcal Therapeutic Approaches. Microorganisms. 2021 Feb 06; 9(2). Park B, Liu GY. PMID: 33562054; PMCID: PMC7915210.
      View in: PubMed   Mentions: 4  
    22. T Cell Immunity and the Quest for Protective Vaccines against Staphylococcus aureus Infection. Microorganisms. 2020 Dec 06; 8(12). Armentrout EI, Liu GY, Martins GA. PMID: 33291260; PMCID: PMC7762175.
      View in: PubMed   Mentions: 16  
    23. Staphylococcus aureus and Hyper-IgE Syndrome. Int J Mol Sci. 2020 Dec 01; 21(23). Park B, Liu GY. PMID: 33271763; PMCID: PMC7729741.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    24. Mortality Risk Profiling of Staphylococcus aureus Bacteremia by Multi-omic Serum Analysis Reveals Early Predictive and Pathogenic Signatures. Cell. 2020 09 03; 182(5):1311-1327.e14. Wozniak JM, Mills RH, Olson J, Caldera JR, Sepich-Poore GD, Carrillo-Terrazas M, Tsai CM, Vargas F, Knight R, Dorrestein PC, Liu GY, Nizet V, Sakoulas G, Rose W, Gonzalez DJ. PMID: 32888495; PMCID: PMC7494005.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansAnimalsCells
    25. Harnessing antifungal immunity in pursuit of a Staphylococcus aureus vaccine strategy. PLoS Pathog. 2020 08; 16(8):e1008733. Paterson MJ, Caldera JR, Nguyen C, Sharma P, Castro AM, Kolar SL, Tsai CM, Limon JJ, Becker CA, Martins GA, Liu GY, Underhill DM. PMID: 32817694; PMCID: PMC7446838.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    26. Photo-Disassembly of Membrane Microdomains Revives Conventional Antibiotics against MRSA. Adv Sci (Weinh). 2020 Mar; 7(6):1903117. Hui J, Dong PT, Liang L, Mandal T, Li J, Ulloa ER, Zhan Y, Jusuf S, Zong C, Seleem MN, Liu GY, Cui Q, Cheng JX. PMID: 32195102; PMCID: PMC7080515.
      View in: PubMed   Mentions: 21     Fields:    
    27. Voices: Overcoming Antibacterial Resistance: Drug Resistance in MRSA – The next big Challenge. Cell Host Microbe. 2019; 26:10. Liu, G.Y.
    28. CspA regulation of Staphylococcus aureus carotenoid levels and σB activity is controlled by YjbH and Spx. Mol Microbiol. 2019 08; 112(2):532-551. Donegan NP, Manna AC, Tseng CW, Liu GY, Cheung AL. PMID: 31074903; PMCID: PMC6703946.
      View in: PubMed   Mentions: 9     Fields:    Translation:Cells
    29. Propionibacterium acnes-induced immunopathology correlates with health and disease association. JCI Insight. 2019 03 07; 4(5). Kolar SL, Tsai CM, Torres J, Fan X, Li H, Liu GY. PMID: 30843879; PMCID: PMC6483503.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    30. Young bone marrow transplantation preserves learning and memory in old mice. Commun Biol. 2019; 2:73. Das MM, Godoy M, Chen S, Moser VA, Avalos P, Roxas KM, Dang I, Yáñez A, Zhang W, Bresee C, Arditi M, Liu GY, Svendsen CN, Goodridge HS. PMID: 30820468; PMCID: PMC6382867.
      View in: PubMed   Mentions: 42  Translation:Animals
    31. YpdA, a putative bacillithiol disulfide reductase, contributes to cellular redox homeostasis and virulence in Staphylococcus aureus. Mol Microbiol. 2019 04; 111(4):1039-1056. Mikheyeva IV, Thomas JM, Kolar SL, Corvaglia AR, Ga?a N, Leo S, Francois P, Liu GY, Rawat M, Cheung AL. PMID: 30636083; PMCID: PMC6458089.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    32. Overexpression of the C-domain of angiotensin-converting enzyme reduces melanoma growth by stimulating M1 macrophage polarization. J Biol Chem. 2019 03 22; 294(12):4368-4380. Khan Z, Cao DY, Giani JF, Bernstein EA, Veiras LC, Fuchs S, Wang Y, Peng Z, Kalkum M, Liu GY, Bernstein KE. PMID: 30670595; PMCID: PMC6433053.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    33. Targeting fundamental pathways to disrupt Staphylococcus aureus survival: clinical implications of recent discoveries. JCI Insight. 2018 03 08; 3(5). Thomsen IP, Liu GY. PMID: 29515041; PMCID: PMC5922289.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    34. O-Acetylation of Peptidoglycan Limits Helper T Cell Priming and Permits Staphylococcus aureus Reinfection. Cell Host Microbe. 2017 Oct 11; 22(4):543-551.e4. Sanchez M, Kolar SL, Müller S, Reyes CN, Wolf AJ, Ogawa C, Singhania R, De Carvalho DD, Arditi M, Underhill DM, Martins GA, Liu GY. PMID: 28943328; PMCID: PMC5679255.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    35. Angiotensin-converting enzyme enhances the oxidative response and bactericidal activity of neutrophils. Blood. 2017 07 20; 130(3):328-339. Khan Z, Shen XZ, Bernstein EA, Giani JF, Eriguchi M, Zhao TV, Gonzalez-Villalobos RA, Fuchs S, Liu GY, Bernstein KE. PMID: 28515091; PMCID: PMC5520468.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansAnimalsCells
    36. RAS and ROS-A Story of Pseudomonas Survival. Cell Host Microbe. 2017 May 10; 21(5):551-552. Kolar SL, Liu GY. PMID: 28494232.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    37. Direct Antimicrobial Activity of IFN-β. J Immunol. 2017 05 15; 198(10):4036-4045. Kaplan A, Lee MW, Wolf AJ, Limon JJ, Becker CA, Ding M, Murali R, Lee EY, Liu GY, Wong GCL, Underhill DM. PMID: 28411186; PMCID: PMC5469413.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    38. Targeting Bacterial Abscess Formation. EBioMedicine. 2016 Oct; 12:16-17. Kolar SL, Liu GY. PMID: 27765641; PMCID: PMC5078668.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    39. Inflammatory properties of antibiotic-treated bacteria. J Leukoc Biol. 2017 01; 101(1):127-134. Wolf AJ, Liu GY, Underhill DM. PMID: 27576461; PMCID: PMC5166437.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    40. Group B Streptococcus Evades Host Immunity by Degrading Hyaluronan. Cell Host Microbe. 2015 Dec 09; 18(6):694-704. Kolar SL, Kyme P, Tseng CW, Soliman A, Kaplan A, Liang J, Nizet V, Jiang D, Murali R, Arditi M, Underhill DM, Liu GY. PMID: 26651945; PMCID: PMC4683412.
      View in: PubMed   Mentions: 41     Fields:    Translation:Cells
    41. Increased Susceptibility of Humanized NSG Mice to Panton-Valentine Leukocidin and Staphylococcus aureus Skin Infection. PLoS Pathog. 2015; 11(11):e1005292. Tseng CW, Biancotti JC, Berg BL, Gate D, Kolar SL, Müller S, Rodriguez MD, Rezai-Zadeh K, Fan X, Beenhouwer DO, Town T, Liu GY. PMID: 26618545; PMCID: PMC4664407.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansAnimalsCells
    42. Poorly Cross-Linked Peptidoglycan in MRSA Due to mecA Induction Activates the Inflammasome and Exacerbates Immunopathology. Cell Host Microbe. 2015 Nov 11; 18(5):604-12. Müller S, Wolf AJ, Iliev ID, Berg BL, Underhill DM, Liu GY. PMID: 26567511; PMCID: PMC4648675.
      View in: PubMed   Mentions: 41     Fields:    Translation:AnimalsCells
    43. Correction: Nicotinamide exacerbates hypoxemia in ventilator-induced lung injury independent of neutrophil infiltration. PLoS One. 2015; 10(5):e0128735. Jones HD, Yoo J, Crother TR, Kyme P, Ben-Shlomo A, Khalafi R, Tseng CW, Parks WC, Arditi M, Liu GY, Shimada K. PMID: 25996479; PMCID: PMC4440726.
      View in: PubMed   Mentions: 2     Fields:    
    44. Nicotinamide exacerbates hypoxemia in ventilator-induced lung injury independent of neutrophil infiltration. PLoS One. 2015; 10(4):e0123460. Jones HD, Yoo J, Crother TR, Kyme P, Ben-Shlomo A, Khalafi R, Tseng CW, Parks WC, Arditi M, Liu GY, Shimada K. PMID: 25875775; PMCID: PMC4395431.
      View in: PubMed   Mentions: 19     Fields:    Translation:Animals
    45. Expanding roles of neutrophils in aging hosts. Curr Opin Immunol. 2014 Aug; 29:43-8. Tseng CW, Liu GY. PMID: 24776646.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansAnimalsCells
    46. Importance of bacillithiol in the oxidative stress response of Staphylococcus aureus. Infect Immun. 2014 Jan; 82(1):316-32. Posada AC, Kolar SL, Dusi RG, Francois P, Roberts AA, Hamilton CJ, Liu GY, Cheung A. PMID: 24166956; PMCID: PMC3911838.
      View in: PubMed   Mentions: 40     Fields:    Translation:Cells
    47. Novel Gemini vitamin D3 analogs: large structure/function analysis and ability to induce antimicrobial peptide. Int J Cancer. 2014 Jan 01; 134(1):207-17. Okamoto R, Gery S, Kuwayama Y, Borregaard N, Ho Q, Alvarez R, Akagi T, Liu GY, Uskokovic MR, Koeffler HP. PMID: 23775785.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    48. Detection of a TLR2 agonist by hematopoietic stem and progenitor cells impacts the function of the macrophages they produce. Eur J Immunol. 2013 Aug; 43(8):2114-25. Yáñez A, Hassanzadeh-Kiabi N, Ng MY, Megías J, Subramanian A, Liu GY, Underhill DM, Gil ML, Goodridge HS. PMID: 23661549; PMCID: PMC3783206.
      View in: PubMed   Mentions: 38     Fields:    Translation:AnimalsCells
    49. Isolation and characterization of antimicrobial compounds in plant extracts against multidrug-resistant Acinetobacter baumannii. PLoS One. 2013; 8(4):e61594. Miyasaki Y, Rabenstein JD, Rhea J, Crouch ML, Mocek UM, Kittell PE, Morgan MA, Nichols WS, Van Benschoten MM, Hardy WD, Liu GY. PMID: 23630600; PMCID: PMC3632535.
      View in: PubMed   Mentions: 41     Fields:    Translation:AnimalsCells
    50. Failure to induce IFN-β production during Staphylococcus aureus infection contributes to pathogenicity. J Immunol. 2012 Nov 01; 189(9):4537-45. Kaplan A, Ma J, Kyme P, Wolf AJ, Becker CA, Tseng CW, Liu GY, Underhill DM. PMID: 23008447; PMCID: PMC3478442.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    51. C/EBPε mediates nicotinamide-enhanced clearance of Staphylococcus aureus in mice. J Clin Invest. 2012 Sep; 122(9):3316-29. Kyme P, Thoennissen NH, Tseng CW, Thoennissen GB, Wolf AJ, Shimada K, Krug UO, Lee K, Müller-Tidow C, Berdel WE, Hardy WD, Gombart AF, Koeffler HP, Liu GY. PMID: 22922257; PMCID: PMC3428083.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansAnimalsCells
    52. Innate immune dysfunctions in aged mice facilitate the systemic dissemination of methicillin-resistant S. aureus. PLoS One. 2012; 7(7):e41454. Tseng CW, Kyme PA, Arruda A, Ramanujan VK, Tawackoli W, Liu GY. PMID: 22844481; PMCID: PMC3406035.
      View in: PubMed   Mentions: 55     Fields:    Translation:AnimalsCells
    53. The pore-forming toxin β hemolysin/cytolysin triggers p38 MAPK-dependent IL-10 production in macrophages and inhibits innate immunity. PLoS Pathog. 2012; 8(7):e1002812. Bebien M, Hensler ME, Davanture S, Hsu LC, Karin M, Park JM, Alexopoulou L, Liu GY, Nizet V, Lawrence T. PMID: 22829768; PMCID: PMC3400567.
      View in: PubMed   Mentions: 37     Fields:    Translation:AnimalsCells
    54. Liposomal encapsulation of vancomycin improves killing of methicillin-resistant Staphylococcus aureus in a murine infection model. J Antimicrob Chemother. 2012 Sep; 67(9):2191-4. Sande L, Sanchez M, Montes J, Wolf AJ, Morgan MA, Omri A, Liu GY. PMID: 22661572.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
    55. Targeting the host-pathogen interface for treatment of Staphylococcus aureus infection. Semin Immunopathol. 2012 Mar; 34(2):299-315. Park B, Liu GY. PMID: 22089960.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    56. Phagosomal degradation increases TLR access to bacterial ligands and enhances macrophage sensitivity to bacteria. J Immunol. 2011 Dec 01; 187(11):6002-10. Wolf AJ, Arruda A, Reyes CN, Kaplan AT, Shimada T, Shimada K, Arditi M, Liu G, Underhill DM. PMID: 22031762; PMCID: PMC3221871.
      View in: PubMed   Mentions: 45     Fields:    Translation:AnimalsCells
    57. Intranasal application of S. epidermidis prevents colonization by methicillin-resistant Staphylococcus aureus in mice. PLoS One. 2011; 6(10):e25880. Park B, Iwase T, Liu GY. PMID: 21998712; PMCID: PMC3187813.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimalsCells
    58. Survival and transmission of community-associated methicillin-resistant Staphylococcus aureus from fomites. Am J Infect Control. 2011 Apr; 39(3):219-25. Desai R, Pannaraj PS, Agopian J, Sugar CA, Liu GY, Miller LG. PMID: 21458684.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimalsCells
    59. Subcutaneous infection of methicillin resistant Staphylococcus aureus (MRSA). J Vis Exp. 2011 Feb 09; (48). Tseng CW, Sanchez-Martinez M, Arruda A, Liu GY. PMID: 21339727; PMCID: PMC3197408.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    60. Carotenoid-related alteration of cell membrane fluidity impacts Staphylococcus aureus susceptibility to host defense peptides. Antimicrob Agents Chemother. 2011 Feb; 55(2):526-31. Mishra NN, Liu GY, Yeaman MR, Nast CC, Proctor RA, McKinnell J, Bayer AS. PMID: 21115796; PMCID: PMC3028772.
      View in: PubMed   Mentions: 115     Fields:    Translation:HumansCells
    61. Angiotensin-converting enzyme overexpression in mouse myelomonocytic cells augments resistance to Listeria and methicillin-resistant Staphylococcus aureus. J Biol Chem. 2010 Dec 10; 285(50):39051-60. Okwan-Duodu D, Datta V, Shen XZ, Goodridge HS, Bernstein EA, Fuchs S, Liu GY, Bernstein KE. PMID: 20937811; PMCID: PMC2998083.
      View in: PubMed   Mentions: 40     Fields:    Translation:AnimalsCells
    62. Polymorphonuclear leukocytes mediate Staphylococcus aureus Panton-Valentine leukocidin-induced lung inflammation and injury. Proc Natl Acad Sci U S A. 2010 Mar 23; 107(12):5587-92. Diep BA, Chan L, Tattevin P, Kajikawa O, Martin TR, Basuino L, Mai TT, Marbach H, Braughton KR, Whitney AR, Gardner DJ, Fan X, Tseng CW, Liu GY, Badiou C, Etienne J, Lina G, Matthay MA, DeLeo FR, Chambers HF. PMID: 20231457; PMCID: PMC2851770.
      View in: PubMed   Mentions: 187     Fields:    Translation:HumansAnimalsCells
    63. Staphylococcus aureus evades lysozyme-based peptidoglycan digestion that links phagocytosis, inflammasome activation, and IL-1beta secretion. Cell Host Microbe. 2010 Jan 21; 7(1):38-49. Shimada T, Park BG, Wolf AJ, Brikos C, Goodridge HS, Becker CA, Reyes CN, Miao EA, Aderem A, Götz F, Liu GY, Underhill DM. PMID: 20114027; PMCID: PMC2818986.
      View in: PubMed   Mentions: 147     Fields:    Translation:AnimalsCells
    64. Staphylococcus aureus Panton-Valentine leukocidin targets muscle tissues in a child with myositis and necrotizing fasciitis. Clin Infect Dis. 2010 Jan 01; 50(1):69-72. Lehman D, Tseng CW, Eells S, Miller LG, Fan X, Beenhouwer DO, Liu GY. PMID: 19995216.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    65. Color me bad: microbial pigments as virulence factors. Trends Microbiol. 2009 Sep; 17(9):406-13. Liu GY, Nizet V. PMID: 19726196; PMCID: PMC2743764.
      View in: PubMed   Mentions: 115     Fields:    Translation:HumansAnimalsCells
    66. Staphylococcus aureus Panton-Valentine leukocidin contributes to inflammation and muscle tissue injury. PLoS One. 2009 Jul 27; 4(7):e6387. Tseng CW, Kyme P, Low J, Rocha MA, Alsabeh R, Miller LG, Otto M, Arditi M, Diep BA, Nizet V, Doherty TM, Beenhouwer DO, Liu GY. PMID: 19633710; PMCID: PMC2711303.
      View in: PubMed   Mentions: 54     Fields:    Translation:AnimalsCells
    67. Inhibition of staphyloxanthin virulence factor biosynthesis in Staphylococcus aureus: in vitro, in vivo, and crystallographic results. J Med Chem. 2009 Jul 09; 52(13):3869-80. Song Y, Liu CI, Lin FY, No JH, Hensler M, Liu YL, Jeng WY, Low J, Liu GY, Nizet V, Wang AH, Oldfield E. PMID: 19456099; PMCID: PMC2753857.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansCells
    68. Molecular pathogenesis of Staphylococcus aureus infection. Pediatr Res. 2009 May; 65(5 Pt 2):71R-77R. Liu GY. PMID: 19190527; PMCID: PMC2919328.
      View in: PubMed   Mentions: 79     Fields:    Translation:HumansCells
    69. Group B streptococcus induces trophoblast death. Microb Pathog. 2008 Sep; 45(3):231-5. Kaplan A, Chung K, Kocak H, Bertolotto C, Uh A, Hobel CJ, Simmons CF, Doran K, Liu GY, Equils O. PMID: 18599257; PMCID: PMC2610016.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    70. A cholesterol biosynthesis inhibitor blocks Staphylococcus aureus virulence. Science. 2008 Mar 07; 319(5868):1391-4. Liu CI, Liu GY, Song Y, Yin F, Hensler ME, Jeng WY, Nizet V, Wang AH, Oldfield E. PMID: 18276850; PMCID: PMC2747771.
      View in: PubMed   Mentions: 200     Fields:    Translation:HumansAnimalsCells
    71. Role of Staphylococcus aureus catalase in niche competition against Streptococcus pneumoniae. J Bacteriol. 2008 Apr; 190(7):2275-8. Park B, Nizet V, Liu GY. PMID: 18223076; PMCID: PMC2293205.
      View in: PubMed   Mentions: 46     Fields:    Translation:AnimalsCells
    72. A group B streptococcal pilus protein promotes phagocyte resistance and systemic virulence. FASEB J. 2008 Jun; 22(6):1715-24. Maisey HC, Quach D, Hensler ME, Liu GY, Gallo RL, Nizet V, Doran KS. PMID: 18198218; PMCID: PMC2721339.
      View in: PubMed   Mentions: 62     Fields:    Translation:HumansAnimalsCells
    73. Impairment of innate immune killing mechanisms by bacteriostatic antibiotics. FASEB J. 2007 Apr; 21(4):1107-16. Kristian SA, Timmer AM, Liu GY, Lauth X, Sal-Man N, Rosenfeld Y, Shai Y, Gallo RL, Nizet V. PMID: 17215486.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    74. DNase expression allows the pathogen group A Streptococcus to escape killing in neutrophil extracellular traps. Curr Biol. 2006 Feb 21; 16(4):396-400. Buchanan JT, Simpson AJ, Aziz RK, Liu GY, Kristian SA, Kotb M, Feramisco J, Nizet V. PMID: 16488874.
      View in: PubMed   Mentions: 304     Fields:    Translation:HumansAnimalsCells
    75. A single streptococcal gene can confer innate immune resistance and virulence to a nonpathogenic bacterium. In Streptococci - New Insights Into an Old Enemy. 2006; (129):223-226. 53. Maisey HC, Hensler ME, Khosravi A, Liu G.Y., Nizet V, Doran KS.
    76. A single streptococcal gene can confer innate immune resistance and virulence to a nonpathogenic bacterium. In Streptococci - New Insights Into an Old Enemy. 2006; (129):223-226. 53. Maisey HC, Hensler ME, Khosravi A, Liu G.Y., Nizet V, Doran KS.
    77. Staphylococcus aureus golden pigment impairs neutrophil killing and promotes virulence through its antioxidant activity. J Exp Med. 2005 Jul 18; 202(2):209-15. Liu GY, Essex A, Buchanan JT, Datta V, Hoffman HM, Bastian JF, Fierer J, Nizet V. PMID: 16009720; PMCID: PMC2213009.
      View in: PubMed   Mentions: 292     Fields:    Translation:HumansAnimalsCells
    78. IKKalpha limits macrophage NF-kappaB activation and contributes to the resolution of inflammation. Nature. 2005 Apr 28; 434(7037):1138-43. Lawrence T, Bebien M, Liu GY, Nizet V, Karin M. PMID: 15858576.
      View in: PubMed   Mentions: 280     Fields:    Translation:AnimalsCells
    79. Virulence role of group B Streptococcus beta-hemolysin/cytolysin in a neonatal rabbit model of early-onset pulmonary infection. J Infect Dis. 2005 Apr 15; 191(8):1287-91. Hensler ME, Liu GY, Sobczak S, Benirschke K, Nizet V, Heldt GP. PMID: 15776375.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
    80. Sword and shield: linked group B streptococcal beta-hemolysin/cytolysin and carotenoid pigment function to subvert host phagocyte defense. Proc Natl Acad Sci U S A. 2004 Oct 05; 101(40):14491-6. Liu GY, Doran KS, Lawrence T, Turkson N, Puliti M, Tissi L, Nizet V. PMID: 15381763; PMCID: PMC521972.
      View in: PubMed   Mentions: 110     Fields:    Translation:HumansAnimalsCells
    81. Extracellular virulence factors of group B Streptococci. Front Biosci. 2004 May 01; 9:1794-802. Liu GY, Nizet V. PMID: 14977587.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    82. Streptococcus agalactiae Beta-hemolysin/cytolysin, in J.E. Alouf, J.H. Freer (Eds):. The Comprehensive Sourcebook of Bacterial Protein Toxins. 2004. Liu G.Y., Nizet V.
    83. Group B streptococcal beta-hemolysin/cytolysin activates neutrophil signaling pathways in brain endothelium and contributes to development of meningitis. J Clin Invest. 2003 Sep; 112(5):736-44. Doran KS, Liu GY, Nizet V. PMID: 12952922; PMCID: PMC182187.
      View in: PubMed   Mentions: 128     Fields:    Translation:HumansCells
    84. Peptide-induced T cell regulation of experimental autoimmune encephalomyelitis: a role for IL-10. Int Immunol. 1999 Oct; 11(10):1625-34. Burkhart C, Liu GY, Anderton SM, Metzler B, Wraith DC. PMID: 10508180.
      View in: PubMed   Mentions: 71     Fields:    Translation:AnimalsCells
    85. Modulation of cytokine production following intranasal administration of antigenic peptide. Transplant Proc. 1998 Dec; 30(8):4186-7. Burkhart C, Liu G, Metzler B, Wraith DC. PMID: 9865341.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    86. Antigen-specific tolerance induction and the immunotherapy of experimental autoimmune disease. Novartis Found Symp. 1998; 215:120-31; discussion 131-6, 186-90. Anderton SM, Burkhart C, Liu GY, Metzler B, Wraith DC. PMID: 9760575.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    87. Low avidity recognition of self-antigen by T cells permits escape from central tolerance. Immunity. 1995 Oct; 3(4):407-15. Liu GY, Fairchild PJ, Smith RM, Prowle JR, Kioussis D, Wraith DC. PMID: 7584132.
      View in: PubMed   Mentions: 144     Fields:    Translation:AnimalsCells
    88. Affinity for class II MHC determines the extent to which soluble peptides tolerize autoreactive T cells in naive and primed adult mice--implications for autoimmunity. Int Immunol. 1995 Aug; 7(8):1255-63. Liu GY, Wraith DC. PMID: 7495732.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    89. Tolerance Induction in An Experimental Model of Autoimmunity (Thesis, U. Cambridge, UK). 1995. Liu, G.Y.
    90. Complete characterization of the expressed immune response genes in Biozzi AB/H mice: structural and functional identity between AB/H and NOD A region molecules. Immunogenetics. 1993; 37(4):296-300. Liu GY, Baker D, Fairchild S, Figueroa F, Quartey-Papafio R, Tone M, Healey D, Cooke A, Turk JL, Wraith DC. PMID: 8420838.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
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