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Conor Caffrey

Title(s)Professor, School of Pharmacy and Pharmaceutical Science
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Collapse Research 
    Collapse research activities and funding
    Translational development of cysteine protease inhibitors to treat hookworm disease
    NIH/NIAID R21AI142452Jul 1, 2019 - Jun 30, 2021
    Role: Principal Investigator
    Reasoning with chemically induced dynamic phenotypes in whole-organism assays
    NIH/NIAID R21AI146719Jun 1, 2019 - May 31, 2021
    Role: Co-Principal Investigator
    Brain Penetrant Microtubule-Stabilizers to Treat CNS-invasive Parasitic Diseases
    NIH R21AI141210Feb 1, 2019 - Jan 31, 2021
    Role: Co-Principal Investigator
    Brain Penetrant Microtubule-Stabilizers to treat CNS-invasive parasitic diseases
    NIH R21AI133394Jun 1, 2018 - May 31, 2021
    Role: Principal Investigator
    Defining the death transcriptome of Schistosoma mansoni to construct a molecular drug screen
    NIH/NIAID R21AI126296Feb 20, 2017 - Jan 31, 2019
    Role: Principal Investigator
    Exploring statins as a small molecule therapy for treatment of schistosomiasis
    NIH R21AI107390Jun 5, 2013 - May 31, 2016
    Role: Principal Investigator
    An automated high throughput phenotypic screen for schistosomiasis drug discovery
    NIH R01AI089896May 15, 2010 - Apr 30, 2015
    Role: Principal Investigator

    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Multi-center screening of the Pathogen Box collection for schistosomiasis drug discovery. Parasit Vectors. 2019 Oct 22; 12(1):493. Maccesi M, Aguiar PHN, Pasche V, Padilla M, Suzuki BM, Montefusco S, Abagyan R, Keiser J, Mourão MM, Caffrey CR. PMID: 31640761; PMCID: PMC6805474.
      View in: PubMed   Mentions: 17     Fields:    Translation:Animals
    2. TPT sulfonate, a single, oral dose schistosomicidal prodrug: In vivo efficacy, disposition and metabolic profiling. Int J Parasitol Drugs Drug Resist. 2018 12; 8(3):571-586. Wolfe AR, Neitz RJ, Burlingame M, Suzuki BM, Lim KC, Scheideler M, Nelson DL, Benet LZ, Caffrey CR. PMID: 30503203; PMCID: PMC6287543.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    3. Odanacatib, a Cathepsin K Cysteine Protease Inhibitor, Kills Hookworm In Vivo. Pharmaceuticals (Basel). 2016 Jul 04; 9(3). Vermeire JJ, Suzuki BM, Caffrey CR. PMID: 27384569; PMCID: PMC5039492.
      View in: PubMed   Mentions: 3  
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