Andrew Mcculloch

Title(s)Professor, Bioengineering
SchoolVc-academic Affairs
Address9500 Gilman Drive #
La Jolla CA 92093
ORCID ORCID Icon0000-0002-1708-5675 Additional info
vCardDownload vCard

    Collapse Biography 
    Collapse Education and Training
    University of Auckland, New ZealandPhD09/1986Engineering Science

    Collapse Overview 

    Collapse Research 
    Collapse Research Activities and Funding
    Systems Biology of Hypertrophic Heart Disease from Molecular Pathways to Organ System
    NIH R01HL137100Feb 13, 2017 - Jan 31, 2021
    Role: Principal Investigator
    Analyzing the Cardiac Power Grid: Adaptive responses to fluctuating local demand
    NIH U01HL122199Sep 15, 2015 - May 31, 2021
    Role: Principal Investigator
    The Cardiac Atlas Project
    NIH R01HL121754Jan 1, 2014 - Jun 30, 2024
    Role: Principal Investigator
    Modeling Cytosolic and Nuclear Ca2+ and IP3 Signaling in Ventricular Myocytes
    NIH R03EB014593Aug 1, 2013 - Jul 31, 2015
    Role: Principal Investigator
    Multi-scale Systems Model of Murine Heart Failure
    NIH R01HL105242Mar 1, 2012 - Feb 28, 2018
    Role: Principal Investigator
    Integrative Bioengineering of Heart, Vessels, and Blood
    NIH T32HL105373Sep 20, 2010 - Aug 31, 2021
    Role: Principal Investigator
    Molecular mechanisms of hypoxia tolerance and susceptibility
    NIH P01HL098053Jul 1, 2010 - Jun 30, 2015
    Role: Co-Investigator
    Multi-Scale Modeling of the Failing Heart for Cardiac Rysynchronization Therapy
    NIH R01HL096544Aug 1, 2009 - Jun 30, 2015
    Role: Principal Investigator
    Training in Multi-scale Analysis of Biological Structure and Function
    NIH T32EB009380Jul 1, 2009 - Jun 30, 2024
    Role: Principal Investigator
    Three-Dimentional Micropatterned Cardiac Tissue Cultures
    NIH R21HL072160Sep 30, 2002 - Jul 31, 2006
    Role: Principal Investigator
    NATIONAL BIOMEDICAL COMPUTATION RESOURCE
    NIH P41RR008605Apr 15, 1994 - Apr 30, 2014
    Role: Co-Investigator
    Biomechanics of the Heart, Vessels, and Blood Cells
    NIH P01HL043026Jul 1, 1990 - May 31, 2007
    Role: Co-Investigator
    IVEM and Image Analysis Resource
    NIH P41RR004050Dec 12, 1988 - Mar 31, 2014
    Role: Co-Investigator
    REGIONAL MECHANICS OF ISCHEMIC VENTRICULAR MYOCARDIUM
    NIH R01HL041603Dec 1, 1988 - Nov 30, 1999
    Role: Principal Investigator
    REGIONAL MECHANICS OF THE INTACT VENTICULAR WALL
    NIH R29HL041603Dec 1, 1988 - Nov 30, 1993
    Role: Principal Investigator
    Molecular Pathways for Hypertrophy and Cardiomyopathy
    NIH P01HL046345Jun 30, 2014
    Role: Co-Investigator

    Collapse ORNG Applications 
    Collapse Faculty Mentoring

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. A universal biventricular coordinate system incorporating valve annuli: Validation in congenital heart disease. Med Image Anal. 2024 Jan 19; 93:103091. Pankewitz LR, Hustad KG, Govil S, Perry JC, Hegde S, Tang R, Omens JH, Young AA, McCulloch AD, Arevalo HJ. PMID: 38301348.
      View in: PubMed   Mentions:    Fields:    
    2. Differential sensitivity to longitudinal and transverse stretch mediates transcriptional responses in mouse neonatal ventricular myocytes. Am J Physiol Heart Circ Physiol. 2024 Feb 01; 326(2):H370-H384. Cao S, Buchholz KS, Tan P, Stowe JC, Wang A, Fowler A, Knaus KR, Khalilimeybodi A, Zambon AC, Omens JH, Saucerman JJ, McCulloch AD. PMID: 38063811.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    3. Multiscale computational modeling of the effects of 2'-deoxy-ATP on cardiac muscle calcium handling. J Appl Phys. 2023 Aug 21; 134(7):074905. Hock MT, Teitgen AE, McCabe KJ, Hirakis SP, Huber GA, Regnier M, Amaro RE, McCammon JA, McCulloch AD. PMID: 37601331; PMCID: PMC10435275.
      View in: PubMed   Mentions:
    4. How can AI accelerate advances in physiology? J Gen Physiol. 2023 06 05; 155(6). McCulloch AD. PMID: 37102985; PMCID: PMC10140544.
      View in: PubMed   Mentions:    Fields:    
    5. Nuclear mechanosignaling in striated muscle diseases. Front Physiol. 2023; 14:1126111. Zhang B, Powers JD, McCulloch AD, Chi NC. PMID: 36960155; PMCID: PMC10027932.
      View in: PubMed   Mentions:
    6. A deep learning approach for fully automated cardiac shape modeling in tetralogy of Fallot. J Cardiovasc Magn Reson. 2023 02 27; 25(1):15. Govil S, Crabb BT, Deng Y, Dal Toso L, Puyol-Antón E, Pushparajah K, Hegde S, Perry JC, Omens JH, Hsiao A, Young AA, McCulloch AD. PMID: 36849960; PMCID: PMC9969707.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    7. Biventricular shape modes discriminate pulmonary valve replacement in tetralogy of Fallot better than imaging indices. Sci Rep. 2023 02 09; 13(1):2335. Govil S, Mauger C, Hegde S, Occleshaw CJ, Yu X, Perry JC, Young AA, Omens JH, McCulloch AD. PMID: 36759522; PMCID: PMC9911768.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    8. An Atlas-Based Analysis of Biventricular Mechanics in Tetralogy of Fallot. Stat Atlases Comput Models Heart. 2022 Sep; 13593:112-122. Govil S, Hegde S, Perry JC, Omens JH, McCulloch AD. PMID: 37251544; PMCID: PMC10226763.
      View in: PubMed   Mentions:
    9. Signaling network model of cardiomyocyte morphological changes in familial cardiomyopathy. J Mol Cell Cardiol. 2023 Jan; 174:1-14. Khalilimeybodi A, Riaz M, Campbell SG, Omens JH, McCulloch AD, Qyang Y, Saucerman JJ. PMID: 36370475; PMCID: PMC10230857.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    10. Forward-Solution Noninvasive Computational Arrhythmia Mapping: The VMAP Study. Circ Arrhythm Electrophysiol. 2022 09; 15(9):e010857. Krummen DE, Villongco CT, Ho G, Schricker AA, Field ME, Sung K, Kacena KA, Martinson MS, Hoffmayer KS, Hsu JC, Raissi F, Feld GK, McCulloch AD, Han FT. PMID: 36069189; PMCID: PMC9509662.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    11. Le Cœur en Sabot: shape associations with adverse events in repaired tetralogy of Fallot. J Cardiovasc Magn Reson. 2022 08 04; 24(1):46. Mîra A, Lamata P, Pushparajah K, Abraham G, Mauger CA, McCulloch AD, Omens JH, Bissell MM, Blair Z, Huffaker T, Tandon A, Engelhardt S, Koehler S, Pickardt T, Beerbaum P, Sarikouch S, Latus H, Greil G, Young AA, Hussain T. PMID: 35922806; PMCID: PMC9351245.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    12. Right Ventricular Flow Vorticity Relationships With Biventricular Shape in Adult Tetralogy of Fallot. Front Cardiovasc Med. 2021; 8:806107. Elsayed A, Mauger CA, Ferdian E, Gilbert K, Scadeng M, Occleshaw CJ, Lowe BS, McCulloch AD, Omens JH, Govil S, Pushparajah K, Young AA. PMID: 35127866; PMCID: PMC8813860.
      View in: PubMed   Mentions: 9  
    13. Subcellular Remodeling in Filamin C Deficient Mouse Hearts Impairs Myocyte Tension Development during Progression of Dilated Cardiomyopathy. Int J Mol Sci. 2022 Jan 14; 23(2). Powers JD, Kirkland NJ, Liu C, Razu SS, Fang X, Engler AJ, Chen J, McCulloch AD. PMID: 35055055; PMCID: PMC8779483.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    14. Three-dimensional transistor arrays for intra- and inter-cellular recording. Nat Nanotechnol. 2022 03; 17(3):292-300. Gu Y, Wang C, Kim N, Zhang J, Wang TM, Stowe J, Nasiri R, Li J, Zhang D, Yang A, Hsu LH, Dai X, Mu J, Liu Z, Lin M, Li W, Wang C, Gong H, Chen Y, Lei Y, Hu H, Li Y, Zhang L, Huang Z, Zhang X, Ahadian S, Banik P, Zhang L, Jiang X, Burke PJ, Khademhosseini A, McCulloch AD, Xu S. PMID: 34949774; PMCID: PMC8994210.
      View in: PubMed   Mentions: 10     Fields:    Translation:Cells
    15. Isolation and reconstruction of cardiac mitochondria from SBEM images using a deep learning-based method. J Struct Biol. 2022 03; 214(1):107806. Hatano A, Someya M, Tanaka H, Sakakima H, Izumi S, Hoshijima M, Ellisman M, McCulloch AD. PMID: 34742833.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    16. Right-left ventricular shape variations in tetralogy of Fallot: associations with pulmonary regurgitation. J Cardiovasc Magn Reson. 2021 10 07; 23(1):105. Mauger CA, Govil S, Chabiniok R, Gilbert K, Hegde S, Hussain T, McCulloch AD, Occleshaw CJ, Omens J, Perry JC, Pushparajah K, Suinesiaputra A, Zhong L, Young AA. PMID: 34615541; PMCID: PMC8496085.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    17. Computational ECG mapping and respiratory gating to optimize stereotactic ablative radiotherapy workflow for refractory ventricular tachycardia. Heart Rhythm O2. 2021 Oct; 2(5):511-520. Ho G, Atwood TF, Bruggeman AR, Moore KL, McVeigh E, Villongco CT, Han FT, Hsu JC, Hoffmayer KS, Raissi F, Lin GY, Schricker A, Woods CE, Cheung JP, Taira AV, McCulloch A, Birgersdotter-Green U, Feld GK, Mundt AJ, Krummen DE. PMID: 34667967; PMCID: PMC8505208.
      View in: PubMed   Mentions: 10  
    18. Cardiac cell type-specific gene regulatory programs and disease risk association. Sci Adv. 2021 05; 7(20). Hocker JD, Poirion OB, Zhu F, Buchanan J, Zhang K, Chiou J, Wang TM, Zhang Q, Hou X, Li YE, Zhang Y, Farah EN, Wang A, McCulloch AD, Gaulton KJ, Ren B, Chi NC, Preissl S. PMID: 33990324; PMCID: PMC8121433.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansCells
    19. Atlas-based methods for efficient characterization of patient-specific ventricular activation patterns. Europace. 2021 03 04; 23(23 Suppl 1):i88-i95. Vincent KP, Forsch N, Govil S, Joblon JM, Omens JH, Perry JC, McCulloch AD. PMID: 33751079; PMCID: PMC7943357.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    20. Computational models of cardiovascular regulatory mechanisms. J Mol Cell Cardiol. 2021 06; 155:111. McCulloch AD, Grandi E, Saucerman JJ. PMID: 33647311.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    21. Mechano-Electric Coupling and Arrhythmogenic Current Generation in a Computational Model of Coupled Myocytes. Front Physiol. 2020; 11:519951. Timmermann V, McCulloch AD. PMID: 33362569; PMCID: PMC7758443.
      View in: PubMed   Mentions: 1  
    22. Prolonged Exposure to Microgravity Reduces Cardiac Contractility and Initiates Remodeling in Drosophila. Cell Rep. 2020 12 08; 33(10):108445. Walls S, Diop S, Birse R, Elmen L, Gan Z, Kalvakuri S, Pineda S, Reddy C, Taylor E, Trinh B, Vogler G, Zarndt R, McCulloch A, Lee P, Bhattacharya S, Bodmer R, Ocorr K. PMID: 33242407; PMCID: PMC7787258.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    23. Maintaining resting cardiac fibroblasts in vitro by disrupting mechanotransduction. PLoS One. 2020; 15(10):e0241390. Gilles G, McCulloch AD, Brakebusch CH, Herum KM. PMID: 33104742; PMCID: PMC7588109.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    24. Modulating the tension-time integral of the cardiac twitch prevents dilated cardiomyopathy in murine hearts. JCI Insight. 2020 10 15; 5(20). Powers JD, Kooiker KB, Mason AB, Teitgen AE, Flint GV, Tardiff JC, Schwartz SD, McCulloch AD, Regnier M, Davis J, Moussavi-Harami F. PMID: 32931484; PMCID: PMC7605524.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    25. Computational analysis of cardiac structure and function in congenital heart disease: Translating discoveries to clinical strategies. J Comput Sci. 2021 May; 52. Forsch N, Govil S, Perry JC, Hegde S, Young AA, Omens JH, McCulloch AD. PMID: 34691293; PMCID: PMC8528218.
      View in: PubMed   Mentions:
    26. Predicting the effects of dATP on cardiac contraction using multiscale modeling of the sarcomere. Arch Biochem Biophys. 2020 11 30; 695:108582. McCabe KJ, Aboelkassem Y, Teitgen AE, Huber GA, McCammon JA, Regnier M, McCulloch AD. PMID: 32956632; PMCID: PMC7721865.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    27. Histamine-induced biphasic activation of RhoA allows for persistent RhoA signaling. PLoS Biol. 2020 09; 18(9):e3000866. Zhang JZ, Nguyen AH, Miyamoto S, Heller Brown J, McCulloch AD, Zhang J. PMID: 32881857; PMCID: PMC7494096.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    28. Methods and sensors for functional genomic studies of cell-cycle transitions in single cells. Physiol Genomics. 2020 10 01; 52(10):468-477. Zambon AC, Hsu T, Kim SE, Klinck M, Stowe J, Henderson LM, Singer D, Patam L, Lim C, McCulloch AD, Hu B, Hickerson AI. PMID: 32866086; PMCID: PMC8828270.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    29. Atlas-based measures of left ventricular shape may improve characterization of adverse remodeling in anthracycline-exposed childhood cancer survivors: a cross-sectional imaging study. Cardiooncology. 2020; 6:13. Narayan HK, Xu R, Forsch N, Govil S, Iukuridze D, Lindenfeld L, Adler E, Hegde S, Tremoulet A, Ky B, Armenian S, Omens J, McCulloch AD. PMID: 32782827; PMCID: PMC7414730.
      View in: PubMed   Mentions: 1  
    30. Direct 3D bioprinting of cardiac micro-tissues mimicking native myocardium. Biomaterials. 2020 10; 256:120204. Liu J, Miller K, Ma X, Dewan S, Lawrence N, Whang G, Chung P, McCulloch AD, Chen S. PMID: 32622020; PMCID: PMC7423764.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    31. Quantification of model and data uncertainty in a network analysis of cardiac myocyte mechanosignalling. Philos Trans A Math Phys Eng Sci. 2020 Jun 12; 378(2173):20190336. Cao S, Aboelkassem Y, Wang A, Valdez-Jasso D, Saucerman JJ, Omens JH, McCulloch AD. PMID: 32448062; PMCID: PMC7287329.
      View in: PubMed   Mentions: 6     Fields:    Translation:Cells
    32. Cardiomyocyte Expression of ZO-1 Is Essential for Normal Atrioventricular Conduction but Does Not Alter Ventricular Function. Circ Res. 2020 07 03; 127(2):284-297. Zhang J, Vincent KP, Peter AK, Klos M, Cheng H, Huang SM, Towne JK, Ferng D, Gu Y, Dalton ND, Chan Y, Li R, Peterson KL, Chen J, McCulloch AD, Knowlton KU, Ross RS. PMID: 32345129; PMCID: PMC7571547.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    33. Regional variations in ex-vivo diffusion tensor anisotropy are associated with cardiomyocyte remodeling in rats after left ventricular pressure overload. J Cardiovasc Magn Reson. 2020 04 02; 22(1):21. Carruth ED, Teh I, Schneider JE, McCulloch AD, Omens JH, Frank LR. PMID: 32241289; PMCID: PMC7114814.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    34. Research Priorities for Heart Failure With Preserved Ejection Fraction: National Heart, Lung, and Blood Institute Working Group Summary. Circulation. 2020 03 24; 141(12):1001-1026. Shah SJ, Borlaug BA, Kitzman DW, McCulloch AD, Blaxall BC, Agarwal R, Chirinos JA, Collins S, Deo RC, Gladwin MT, Granzier H, Hummel SL, Kass DA, Redfield MM, Sam F, Wang TJ, Desvigne-Nickens P, Adhikari BB. PMID: 32202936; PMCID: PMC7101072.
      View in: PubMed   Mentions: 122     Fields:    Translation:Humans
    35. Improved compressed sensing and super-resolution of cardiac diffusion MRI with structure-guided total variation. Magn Reson Med. 2020 10; 84(4):1868-1880. Teh I, McClymont D, Carruth E, Omens J, McCulloch A, Schneider JE. PMID: 32125040; PMCID: PMC8629124.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    36. Syndecan-4 Protects the Heart From the Profibrotic Effects of Thrombin-Cleaved Osteopontin. J Am Heart Assoc. 2020 02 04; 9(3):e013518. Herum KM, Romaine A, Wang A, Melleby AO, Strand ME, Pacheco J, Braathen B, Dunér P, Tønnessen T, Lunde IG, Sjaastad I, Brakebusch C, McCulloch AD, Gomez MF, Carlson CR, Christensen G. PMID: 32000579; PMCID: PMC7033859.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    37. Predictions of hypertrophy and its regression in response to pressure overload. Biomech Model Mechanobiol. 2020 Jun; 19(3):1079-1089. Yoshida K, McCulloch AD, Omens JH, Holmes JW. PMID: 31813071; PMCID: PMC8071348.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    38. Arrhythmogenic Current Generation by Myofilament-Triggered Ca2+ Release and Sarcomere Heterogeneity. Biophys J. 2019 12 17; 117(12):2471-2485. Timmermann V, Edwards AG, Wall ST, Sundnes J, McCulloch AD. PMID: 31810659; PMCID: PMC6990379.
      View in: PubMed   Mentions: 8     Fields:    Translation:Cells
    39. Multiscale Models of Cardiac Muscle Biophysics and Tissue Remodeling in Hypertrophic Cardiomyopathies. Curr Opin Biomed Eng. 2019 Sep; 11:35-44. Aboelkassem Y, Powers JD, McCabe KJ, McCulloch AD. PMID: 31886450; PMCID: PMC6934086.
      View in: PubMed   Mentions: 3  
    40. Optimization Framework for Patient-Specific Cardiac Modeling. Cardiovasc Eng Technol. 2019 12; 10(4):553-567. Mineroff J, McCulloch AD, Krummen D, Ganapathysubramanian B, Krishnamurthy A. PMID: 31531820; PMCID: PMC6868335.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    41. A Stochastic Multiscale Model of Cardiac Thin Filament Activation Using Brownian-Langevin Dynamics. Biophys J. 2019 12 17; 117(12):2255-2272. Aboelkassem Y, McCabe KJ, Huber GA, Regnier M, McCammon JA, McCulloch AD. PMID: 31547973; PMCID: PMC6990154.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    42. Mechanical regulation of gene expression in cardiac myocytes and fibroblasts. Nat Rev Cardiol. 2019 06; 16(6):361-378. Saucerman JJ, Tan PM, Buchholz KS, McCulloch AD, Omens JH. PMID: 30683889; PMCID: PMC6525041.
      View in: PubMed   Mentions: 76     Fields:    Translation:HumansAnimalsCells
    43. Properties of cardiac conduction in a cell-based computational model. PLoS Comput Biol. 2019 05; 15(5):e1007042. Jæger KH, Edwards AG, McCulloch A, Tveito A. PMID: 31150383; PMCID: PMC6561587.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    44. Cardiac myosin activation with 2-deoxy-ATP via increased electrostatic interactions with actin. Proc Natl Acad Sci U S A. 2019 06 04; 116(23):11502-11507. Powers JD, Yuan CC, McCabe KJ, Murray JD, Childers MC, Flint GV, Moussavi-Harami F, Mohran S, Castillo R, Zuzek C, Ma W, Daggett V, McCulloch AD, Irving TC, Regnier M. PMID: 31110001; PMCID: PMC6561254.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    45. A demonstration of modularity, reuse, reproducibility, portability and scalability for modeling and simulation of cardiac electrophysiology using Kepler Workflows. PLoS Comput Biol. 2019 03; 15(3):e1006856. Yang PC, Purawat S, Ieong PU, Jeng MT, DeMarco KR, Vorobyov I, McCulloch AD, Altintas I, Amaro RE, Clancy CE. PMID: 30849072; PMCID: PMC6426265.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    46. Array atomic force microscopy for real-time multiparametric analysis. Proc Natl Acad Sci U S A. 2019 03 26; 116(13):5872-5877. Yang Q, Ma Q, Herum KM, Wang C, Patel N, Lee J, Wang S, Yen TM, Wang J, Tang H, Lo YH, Head BP, Azam F, Xu S, Cauwenberghs G, McCulloch AD, John S, Liu Z, Lal R. PMID: 30850523; PMCID: PMC6442637.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    47. Long QT syndrome caveolin-3 mutations differentially modulate Kv 4 and Cav 1.2 channels to contribute to action potential prolongation. J Physiol. 2019 03; 597(6):1531-1551. Tyan L, Foell JD, Vincent KP, Woon MT, Mesquitta WT, Lang D, Best JM, Ackerman MJ, McCulloch AD, Glukhov AV, Balijepalli RC, Kamp TJ. PMID: 30588629; PMCID: PMC6418751.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    48. 3D printed micro-scale force gauge arrays to improve human cardiac tissue maturation and enable high throughput drug testing. Acta Biomater. 2019 09 01; 95:319-327. Ma X, Dewan S, Liu J, Tang M, Miller KL, Yu C, Lawrence N, McCulloch AD, Chen S. PMID: 30576862; PMCID: PMC6584548.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    49. An Iterative Diffeomorphic Algorithm for Registration of Subdivision Surfaces: Application to Congenital Heart Disease. Annu Int Conf IEEE Eng Med Biol Soc. 2018 Jul; 2018:596-599. Mauger C, Gilbert K, Suinesiaputra A, Pontre B, Omens J, McCulloch A, Young A. PMID: 30440467; PMCID: PMC8175008.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    50. Tissue-Specific Optical Mapping Models of Swine Atria Informed by Optical Coherence Tomography. Biophys J. 2018 03 27; 114(6):1477-1489. Lye TH, Vincent KP, McCulloch AD, Hendon CP. PMID: 29590604; PMCID: PMC5883619.
      View in: PubMed   Mentions: 9     Fields:    Translation:Animals
    51. Efficient Computational Modeling of Human Ventricular Activation and Its Electrocardiographic Representation: A Sensitivity Study. Cardiovasc Eng Technol. 2018 09; 9(3):447-467. Cranford JP, O'Hara TJ, Villongco CT, Hafez OM, Blake RC, Loscalzo J, Fattebert JL, Richards DF, Zhang X, Glosli JN, McCulloch AD, Krummen DE, Lightstone FC, Wong SE. PMID: 29549620; PMCID: PMC6095770.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    52. Decreasing Compensatory Ability of Concentric Ventricular Hypertrophy in Aortic-Banded Rat Hearts. Front Physiol. 2018; 9:37. Lewalle A, Land S, Carruth E, Frank LR, Lamata P, Omens JH, McCulloch AD, Niederer SA, Smith NP. PMID: 29527171; PMCID: PMC5829063.
      View in: PubMed   Mentions: 2  
    53. Perspectives on Sharing Models and Related Resources in Computational Biomechanics Research. J Biomech Eng. 2018 02 01; 140(2). Erdemir A, Hunter PJ, Holzapfel GA, Loew LM, Middleton J, Jacobs CR, Nithiarasu P, Löhner R, Wei G, Winkelstein BA, Barocas VH, Guilak F, Ku JP, Hicks JL, Delp SL, Sacks M, Weiss JA, Ateshian GA, Maas SA, McCulloch AD, Peng GCY. PMID: 29247253; PMCID: PMC5821103.
      View in: PubMed   Mentions: 6     Fields:    
    54. Atlas-Based Computational Analysis of Heart Shape and Function in Congenital Heart Disease. J Cardiovasc Transl Res. 2018 04; 11(2):123-132. Gilbert K, Forsch N, Hegde S, Mauger C, Omens JH, Perry JC, Pontré B, Suinesiaputra A, Young AA, McCulloch AD. PMID: 29294215; PMCID: PMC5910190.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    55. Predictive model identifies key network regulators of cardiomyocyte mechano-signaling. PLoS Comput Biol. 2017 Nov; 13(11):e1005854. Tan PM, Buchholz KS, Omens JH, McCulloch AD, Saucerman JJ. PMID: 29131824; PMCID: PMC5703578.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
    56. An integrative appraisal of mechano-electric feedback mechanisms in the heart. Prog Biophys Mol Biol. 2017 11; 130(Pt B):404-417. Timmermann V, Dejgaard LA, Haugaa KH, Edwards AG, Sundnes J, McCulloch AD, Wall ST. PMID: 28851517; PMCID: PMC5716869.
      View in: PubMed   Mentions: 14     Fields:    Translation:Cells
    57. Rotors exhibit greater surface ECG variation during ventricular fibrillation than focal sources due to wavebreak, secondary rotors, and meander. J Cardiovasc Electrophysiol. 2017 Oct; 28(10):1158-1166. Ho G, Villongco CT, Yousefian O, Bradshaw A, Nguyen A, Faiwiszewski Y, Hayase J, Rappel WJ, McCulloch AD, Krummen DE. PMID: 28670858; PMCID: PMC7909714.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    58. Transcriptomic analysis identifies a role of PI3K-Akt signalling in the responses of skeletal muscle to acute hypoxia in vivo. J Physiol. 2017 09 01; 595(17):5797-5813. Gan Z, Powell FL, Zambon AC, Buchholz KS, Fu Z, Ocorr K, Bodmer R, Moya EA, Stowe JC, Haddad GG, McCulloch AD. PMID: 28688178; PMCID: PMC5577531.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    59. The Soft- and Hard-Heartedness of Cardiac Fibroblasts: Mechanotransduction Signaling Pathways in Fibrosis of the Heart. J Clin Med. 2017 May 19; 6(5). Herum KM, Lunde IG, McCulloch AD, Christensen G. PMID: 28534817; PMCID: PMC5447944.
      View in: PubMed   Mentions: 68  
    60. Mechanical regulation of cardiac fibroblast profibrotic phenotypes. Mol Biol Cell. 2017 Jul 07; 28(14):1871-1882. Herum KM, Choppe J, Kumar A, Engler AJ, McCulloch AD. PMID: 28468977; PMCID: PMC5541838.
      View in: PubMed   Mentions: 96     Fields:    Translation:AnimalsCells
    61. Insights and Challenges of Multi-Scale Modeling of Sarcomere Mechanics in cTn and Tm DCM Mutants-Genotype to Cellular Phenotype. Front Physiol. 2017; 8:151. Dewan S, McCabe KJ, Regnier M, McCulloch AD. PMID: 28352236; PMCID: PMC5348544.
      View in: PubMed   Mentions: 6  
    62. Model of Human Fetal Growth in Hypoplastic Left Heart Syndrome: Reduced Ventricular Growth Due to Decreased Ventricular Filling and Altered Shape. Front Pediatr. 2017; 5:25. Dewan S, Krishnamurthy A, Kole D, Conca G, Kerckhoffs R, Puchalski MD, Omens JH, Sun H, Nigam V, McCulloch AD. PMID: 28275592; PMCID: PMC5319967.
      View in: PubMed   Mentions: 5  
    63. Non-invasive, model-based measures of ventricular electrical dyssynchrony for predicting CRT outcomes. Europace. 2016 Dec; 18(suppl 4):iv104-iv112. Villongco CT, Krummen DE, Omens JH, McCulloch AD. PMID: 28011837; PMCID: PMC5225967.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    64. Transmural gradients of myocardial structure and mechanics: Implications for fiber stress and strain in pressure overload. Prog Biophys Mol Biol. 2016 Dec; 122(3):215-226. Carruth ED, McCulloch AD, Omens JH. PMID: 27845176; PMCID: PMC5161628.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimals
    65. Evaluation of non-Gaussian diffusion in cardiac MRI. Magn Reson Med. 2017 09; 78(3):1174-1186. McClymont D, Teh I, Carruth E, Omens J, McCulloch A, Whittington HJ, Kohl P, Grau V, Schneider JE. PMID: 27670633; PMCID: PMC5366286.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    66. Atlas-Based Ventricular Shape Analysis for Understanding Congenital Heart Disease. Prog Pediatr Cardiol. 2016 Dec; 43:61-69. Farrar G, Suinesiaputra A, Gilbert K, Perry JC, Hegde S, Marsden A, Young AA, Omens JH, McCulloch AD. PMID: 28082823; PMCID: PMC5222611.
      View in: PubMed   Mentions: 15  
    67. Improving assessment of congenital heart disease through rapid patient specific modeling. Annu Int Conf IEEE Eng Med Biol Soc. 2016 Aug; 2016:1228-1231. Gilbert K, Farrar G, Cowan B, Suinesiaputra A, Occleshaw C, Pontre B, Perry J, Hegde S, Omens J, McCulloch A, Young A. PMID: 28268546.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    68. A Computational Modeling and Simulation Approach to Investigate Mechanisms of Subcellular cAMP Compartmentation. PLoS Comput Biol. 2016 07; 12(7):e1005005. Yang PC, Boras BW, Jeng MT, Docken SS, Lewis TJ, McCulloch AD, Harvey RD, Clancy CE. PMID: 27409243; PMCID: PMC4943723.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    69. Cardiac image modelling: Breadth and depth in heart disease. Med Image Anal. 2016 10; 33:38-43. Suinesiaputra A, McCulloch AD, Nash MP, Pontre B, Young AA. PMID: 27349830; PMCID: PMC5123588.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    70. Effects of Cardiac Troponin I Mutation P83S on Contractile Properties and the Modulation by PKA-Mediated Phosphorylation. J Phys Chem B. 2016 08 25; 120(33):8238-53. Cheng Y, Lindert S, Oxenford L, Tu AY, McCulloch AD, Regnier M. PMID: 27150586; PMCID: PMC5001945.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    71. Molecular Effects of cTnC DCM Mutations on Calcium Sensitivity and Myofilament Activation-An Integrated Multiscale Modeling Study. J Phys Chem B. 2016 08 25; 120(33):8264-75. Dewan S, McCabe KJ, Regnier M, McCulloch AD, Lindert S. PMID: 27133568; PMCID: PMC5001916.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    72. Computing rates of Markov models of voltage-gated ion channels by inverting partial differential equations governing the probability density functions of the conducting and non-conducting states. Math Biosci. 2016 07; 277:126-35. Tveito A, Lines GT, Edwards AG, McCulloch A. PMID: 27154008; PMCID: PMC4894014.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    73. Multi-scale Modeling of the Cardiovascular System: Disease Development, Progression, and Clinical Intervention. Ann Biomed Eng. 2016 09; 44(9):2642-60. Zhang Y, Barocas VH, Berceli SA, Clancy CE, Eckmann DM, Garbey M, Kassab GS, Lochner DR, McCulloch AD, Tran-Son-Tay R, Trayanova NA. PMID: 27138523; PMCID: PMC4983486.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    74. Desmosomal junctions are necessary for adult sinus node function. Cardiovasc Res. 2016 08 01; 111(3):274-86. Mezzano V, Liang Y, Wright AT, Lyon RC, Pfeiffer E, Song MY, Gu Y, Dalton ND, Scheinman M, Peterson KL, Evans SM, Fowler S, Cerrone M, McCulloch AD, Sheikh F. PMID: 27097650; PMCID: PMC4957488.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    75. Electrophysiology and metabolism of caveolin-3-overexpressing mice. Basic Res Cardiol. 2016 May; 111(3):28. Schilling JM, Horikawa YT, Zemljic-Harpf AE, Vincent KP, Tyan L, Yu JK, McCulloch AD, Balijepalli RC, Patel HH, Roth DM. PMID: 27023865; PMCID: PMC5336321.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    76. Systems Biophysics: Multiscale Biophysical Modeling of Organ Systems. Biophys J. 2016 Mar 08; 110(5):1023-7. McCulloch AD. PMID: 26958877; PMCID: PMC4788749.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimals
    77. Biomechanics Simulations Using Cubic Hermite Meshes with Extraordinary Nodes for Isogeometric Cardiac Modeling. Comput Aided Geom Des. 2016 Mar; 43:27-38. Krishnamurthy A, Gonzales MJ, Sturgeon G, Segars WP, McCulloch AD. PMID: 27182096; PMCID: PMC4862616.
      View in: PubMed   Mentions: 6  
    78. A Protocol to Collect Specific Mouse Skeletal Muscles for Metabolomics Studies. Methods Mol Biol. 2016; 1375:169-79. Gan Z, Fu Z, Stowe JC, Powell FL, McCulloch AD. PMID: 26003134.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    79. 3D cardiac μtissues within a microfluidic device with real-time contractile stress readout. Lab Chip. 2016 Jan 07; 16(1):153-62. Aung A, Bhullar IS, Theprungsirikul J, Davey SK, Lim HL, Chiu YJ, Ma X, Dewan S, Lo YH, McCulloch A, Varghese S. PMID: 26588203; PMCID: PMC4681661.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    80. Bitopic Sphingosine 1-Phosphate Receptor 3 (S1P3) Antagonist Rescue from Complete Heart Block: Pharmacological and Genetic Evidence for Direct S1P3 Regulation of Mouse Cardiac Conduction. Mol Pharmacol. 2016 Jan; 89(1):176-86. Sanna MG, Vincent KP, Repetto E, Nguyen N, Brown SJ, Abgaryan L, Riley SW, Leaf NB, Cahalan SM, Kiosses WB, Kohno Y, Brown JH, McCulloch AD, Rosen H, Gonzalez-Cabrera PJ. PMID: 26494861; PMCID: PMC4702096.
      View in: PubMed   Mentions: 22     Fields:    Translation:Animals
    81. Troponin I Mutations R146G and R21C Alter Cardiac Troponin Function, Contractile Properties, and Modulation by Protein Kinase A (PKA)-mediated Phosphorylation. J Biol Chem. 2015 Nov 13; 290(46):27749-66. Cheng Y, Rao V, Tu AY, Lindert S, Wang D, Oxenford L, McCulloch AD, McCammon JA, Regnier M. PMID: 26391394; PMCID: PMC4646022.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    82. Bridging scales through multiscale modeling: a case study on protein kinase A. Front Physiol. 2015; 6:250. Boras BW, Hirakis SP, Votapka LW, Malmstrom RD, Amaro RE, McCulloch AD. PMID: 26441670; PMCID: PMC4563169.
      View in: PubMed   Mentions: 10  
    83. Intramyocardial injection of hydrogel with high interstitial spread does not impact action potential propagation. Acta Biomater. 2015 Oct; 26:13-22. Suarez SL, Rane AA, Muñoz A, Wright AT, Zhang SX, Braden RL, Almutairi A, McCulloch AD, Christman KL. PMID: 26265060; PMCID: PMC4772723.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    84. High-order finite element methods for cardiac monodomain simulations. Front Physiol. 2015; 6:217. Vincent KP, Gonzales MJ, Gillette AK, Villongco CT, Pezzuto S, Omens JH, Holst MJ, McCulloch AD. PMID: 26300783; PMCID: PMC4525671.
      View in: PubMed   Mentions: 8  
    85. Endothelin receptor B, a candidate gene from human studies at high altitude, improves cardiac tolerance to hypoxia in genetically engineered heterozygote mice. Proc Natl Acad Sci U S A. 2015 Aug 18; 112(33):10425-30. Stobdan T, Zhou D, Ao-Ieong E, Ortiz D, Ronen R, Hartley I, Gan Z, McCulloch AD, Bafna V, Cabrales P, Haddad GG. PMID: 26240367; PMCID: PMC4547246.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimals
    86. Creating shape templates for patient specific biventricular modeling in congenital heart disease. Annu Int Conf IEEE Eng Med Biol Soc. 2015 Aug; 2015:679-82. Gilbert K, Farrar G, Cowan BR, Suinesiaputra A, Occleshaw C, Pontre B, Perry J, Hegde S, Marsden A, Omens J, McCulloch A, Young AA. PMID: 26736353; PMCID: PMC5797697.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    87. Atrial-selective targeting of arrhythmogenic phase-3 early afterdepolarizations in human myocytes. J Mol Cell Cardiol. 2016 07; 96:63-71. Morotti S, McCulloch AD, Bers DM, Edwards AG, Grandi E. PMID: 26241847; PMCID: PMC4734906.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    88. HIF1α Represses Cell Stress Pathways to Allow Proliferation of Hypoxic Fetal Cardiomyocytes. Dev Cell. 2015 Jun 08; 33(5):507-21. Guimarães-Camboa N, Stowe J, Aneas I, Sakabe N, Cattaneo P, Henderson L, Kilberg MS, Johnson RS, Chen J, McCulloch AD, Nobrega MA, Evans SM, Zambon AC. PMID: 26028220; PMCID: PMC4509618.
      View in: PubMed   Mentions: 77     Fields:    Translation:AnimalsCells
    89. Increased cell membrane capacitance is the dominant mechanism of stretch-dependent conduction slowing in the rabbit heart: a computational study. Cell Mol Bioeng. 2015 Jun 01; 8(2):237-246. de Oliveira BL, Pfeiffer ER, Sundnes J, Wall ST, McCulloch AD. PMID: 27087858; PMCID: PMC4830494.
      View in: PubMed   Mentions: 6  
    90. Left Ventricular Diastolic and Systolic Material Property Estimation from Image Data: LV Mechanics Challenge. Stat Atlases Comput Models Heart. 2015 Jan; 8896:63-73. Krishnamurthy A, Villongco C, Beck A, Omens J, McCulloch A. PMID: 25729778; PMCID: PMC4339056.
      View in: PubMed   Mentions: 4  
    91. Multi-bio and multi-scale systems biology. Prog Biophys Mol Biol. 2015 Jan; 117(1):1-3. Henney A, Hunter P, McCulloch A, Noble D. PMID: 25783046.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    92. Structural contributions to fibrillatory rotors in a patient-derived computational model of the atria. Europace. 2014 Nov; 16 Suppl 4:iv3-iv10. Gonzales MJ, Vincent KP, Rappel WJ, Narayan SM, McCulloch AD. PMID: 25362167; PMCID: PMC4565557.
      View in: PubMed   Mentions: 38     Fields:    Translation:Humans
    93. Computational studies of the effect of the S23D/S24D troponin I mutation on cardiac troponin structural dynamics. Biophys J. 2014 Oct 07; 107(7):1675-85. Cheng Y, Lindert S, Kekenes-Huskey P, Rao VS, Solaro RJ, Rosevear PR, Amaro R, McCulloch AD, McCammon JA, Regnier M. PMID: 25296321; PMCID: PMC4190606.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansCells
    94. Caveolae in ventricular myocytes are required for stretch-dependent conduction slowing. J Mol Cell Cardiol. 2014 Nov; 76:265-74. Pfeiffer ER, Wright AT, Edwards AG, Stowe JC, McNall K, Tan J, Niesman I, Patel HH, Roth DM, Omens JH, McCulloch AD. PMID: 25257915; PMCID: PMC4250283.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    95. Nonequilibrium reactivation of Na+ current drives early afterdepolarizations in mouse ventricle. Circ Arrhythm Electrophysiol. 2014 Dec; 7(6):1205-13. Edwards AG, Grandi E, Hake JE, Patel S, Li P, Miyamoto S, Omens JH, Heller Brown J, Bers DM, McCulloch AD. PMID: 25236710; PMCID: PMC4301603.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    96. Using Markov state models to develop a mechanistic understanding of protein kinase A regulatory subunit RIα activation in response to cAMP binding. J Biol Chem. 2014 Oct 24; 289(43):30040-51. Boras BW, Kornev A, Taylor SS, McCulloch AD. PMID: 25202018; PMCID: PMC4208011.
      View in: PubMed   Mentions: 21     Fields:    Translation:Cells
    97. PKA phosphorylation of cardiac troponin I modulates activation and relaxation kinetics of ventricular myofibrils. Biophys J. 2014 Sep 02; 107(5):1196-1204. Rao V, Cheng Y, Lindert S, Wang D, Oxenford L, McCulloch AD, McCammon JA, Regnier M. PMID: 25185555; PMCID: PMC4156663.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
    98. Patient-specific modeling of ventricular activation pattern using surface ECG-derived vectorcardiogram in bundle branch block. Prog Biophys Mol Biol. 2014 Aug; 115(2-3):305-13. Villongco CT, Krummen DE, Stark P, Omens JH, McCulloch AD. PMID: 25110279; PMCID: PMC4254140.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    99. Timing and magnitude of systolic stretch affect myofilament activation and mechanical work. Am J Physiol Heart Circ Physiol. 2014 Aug 01; 307(3):H353-60. Tangney JR, Campbell SG, McCulloch AD, Omens JH. PMID: 24878774; PMCID: PMC4182292.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    100. Toward a hierarchy of mechanisms in CaMKII-mediated arrhythmia. Front Pharmacol. 2014; 5:110. Vincent KP, McCulloch AD, Edwards AG. PMID: 24994983; PMCID: PMC4062880.
      View in: PubMed   Mentions: 10  
    101. MAAMD: a workflow to standardize meta-analyses and comparison of affymetrix microarray data. BMC Bioinformatics. 2014 Mar 12; 15:69. Gan Z, Wang J, Salomonis N, Stowe JC, Haddad GG, McCulloch AD, Altintas I, Zambon AC. PMID: 24621103; PMCID: PMC3975178.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    102. Calcium and IP3 dynamics in cardiac myocytes: experimental and computational perspectives and approaches. Front Pharmacol. 2014; 5:35. Hohendanner F, McCulloch AD, Blatter LA, Michailova AP. PMID: 24639654; PMCID: PMC3944219.
      View in: PubMed   Mentions: 30  
    103. Targeted ablation of nesprin 1 and nesprin 2 from murine myocardium results in cardiomyopathy, altered nuclear morphology and inhibition of the biomechanical gene response. PLoS Genet. 2014 Feb; 10(2):e1004114. Banerjee I, Zhang J, Moore-Morris T, Pfeiffer E, Buchholz KS, Liu A, Ouyang K, Stroud MJ, Gerace L, Evans SM, McCulloch A, Chen J. PMID: 24586179; PMCID: PMC3930490.
      View in: PubMed   Mentions: 75     Fields:    Translation:HumansAnimalsCells
    104. Computational modeling of subcellular transport and signaling. Curr Opin Struct Biol. 2014 Apr; 25:92-7. Hake J, Kekenes-Huskey PM, McCulloch AD. PMID: 24509246; PMCID: PMC4040296.
      View in: PubMed   Mentions: 12     Fields:    Translation:Cells
    105. Biomechanics of cardiac electromechanical coupling and mechanoelectric feedback. J Biomech Eng. 2014 Feb; 136(2):021007. Pfeiffer ER, Tangney JR, Omens JH, McCulloch AD. PMID: 24337452; PMCID: PMC4023651.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansAnimalsCells
    106. A novel computational model of mouse myocyte electrophysiology to assess the synergy between Na+ loading and CaMKII. J Physiol. 2014 Mar 15; 592(6):1181-97. Morotti S, Edwards AG, McCulloch AD, Bers DM, Grandi E. PMID: 24421356; PMCID: PMC3961080.
      View in: PubMed   Mentions: 61     Fields:    Translation:AnimalsCells
    107. Using Kepler for Tool Integration in Microarray Analysis Workflows. Procedia Comput Sci. 2014; 29:2162-2167. Gan Z, Stowe JC, Altintas I, McCulloch AD, Zambon AC. PMID: 26605000; PMCID: PMC4655117.
      View in: PubMed   Mentions:
    108. Molecular and subcellular-scale modeling of nucleotide diffusion in the cardiac myofilament lattice. Biophys J. 2013 Nov 05; 105(9):2130-40. Kekenes-Huskey PM, Liao T, Gillette AK, Hake JE, Zhang Y, Michailova AP, McCulloch AD, McCammon JA. PMID: 24209858; PMCID: PMC3835335.
      View in: PubMed   Mentions: 11     Fields:    Translation:Cells
    109. Connexin defects underlie arrhythmogenic right ventricular cardiomyopathy in a novel mouse model. Hum Mol Genet. 2014 Mar 01; 23(5):1134-50. Lyon RC, Mezzano V, Wright AT, Pfeiffer E, Chuang J, Banares K, Castaneda A, Ouyang K, Cui L, Contu R, Gu Y, Evans SM, Omens JH, Peterson KL, McCulloch AD, Sheikh F. PMID: 24108106; PMCID: PMC3919010.
      View in: PubMed   Mentions: 52     Fields:    Translation:AnimalsCells
    110. Sensitivity of rabbit ventricular action potential and Ca²⁺ dynamics to small variations in membrane currents and ion diffusion coefficients. Biomed Res Int. 2013; 2013:565431. Lo YH, Peachey T, Abramson D, McCulloch A, Michailova A. PMID: 24222910; PMCID: PMC3814049.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    111. Patient-Specific Models of Cardiac Biomechanics. J Comput Phys. 2013 Jul 01; 244:4-21. Krishnamurthy A, Villongco CT, Chuang J, Frank LR, Nigam V, Belezzuoli E, Stark P, Krummen DE, Narayan S, Omens JH, McCulloch AD, Kerckhoffs RC. PMID: 23729839; PMCID: PMC3667962.
      View in: PubMed   Mentions: 86  
    112. Multi-core CPU or GPU-accelerated Multiscale Modeling for Biomolecular Complexes. Mol Based Math Biol. 2013 Jul; 1. Liao T, Zhang Y, Kekenes-Huskey PM, Cheng Y, Michailova A, McCulloch AD, Holst M, McCammon JA. PMID: 24352481; PMCID: PMC3858848.
      View in: PubMed   Mentions: 6  
    113. The promise of CaMKII inhibition for heart disease: preventing heart failure and arrhythmias. Expert Opin Ther Targets. 2013 Aug; 17(8):889-903. Westenbrink BD, Edwards AG, McCulloch AD, Brown JH. PMID: 23789646; PMCID: PMC5551677.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimals
    114. Myofiber prestretch magnitude determines regional systolic function during ectopic activation in the tachycardia-induced failing canine heart. Am J Physiol Heart Circ Physiol. 2013 Jul 15; 305(2):H192-202. Howard EJ, Kerckhoffs RC, Vincent KP, Krishnamurthy A, Villongco CT, Mulligan LJ, McCulloch AD, Omens JH. PMID: 23666676; PMCID: PMC3726954.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    115. Adenylyl cyclase 6 deletion increases mortality during sustained β-adrenergic receptor stimulation. J Mol Cell Cardiol. 2013 Jul; 60:60-7. Tang T, Lai NC, Wright AT, Gao MH, Lee P, Guo T, Tang R, McCulloch AD, Hammond HK. PMID: 23587598; PMCID: PMC3987812.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    116. Novel role for vinculin in ventricular myocyte mechanics and dysfunction. Biophys J. 2013 Apr 02; 104(7):1623-33. Tangney JR, Chuang JS, Janssen MS, Krishnamurthy A, Liao P, Hoshijima M, Wu X, Meininger GA, Muthuchamy M, Zemljic-Harpf A, Ross RS, Frank LR, McCulloch AD, Omens JH. PMID: 23561539; PMCID: PMC3617425.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    117. A three-dimensional finite element model of human atrial anatomy: new methods for cubic Hermite meshes with extraordinary vertices. Med Image Anal. 2013 Jul; 17(5):525-37. Gonzales MJ, Sturgeon G, Krishnamurthy A, Hake J, Jonas R, Stark P, Rappel WJ, Narayan SM, Zhang Y, Segars WP, McCulloch AD. PMID: 23602918; PMCID: PMC3660421.
      View in: PubMed   Mentions: 32     Fields:    Translation:Humans
    118. Mechanical discoordination increases continuously after the onset of left bundle branch block despite constant electrical dyssynchrony in a computational model of cardiac electromechanics and growth. Europace. 2012 Nov; 14 Suppl 5:v65-v72. Kerckhoffs RC, Omens JH, McCulloch AD. PMID: 23104917; PMCID: PMC3482618.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    119. What can modelling provide to cardiac physiology? J Physiol. 2012 Sep 15; 590(18):4401-2. Smith NP, McCulloch AD, Paterson DJ. PMID: 22988258; PMCID: PMC3477748.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    120. Modeling effects of L-type ca(2+) current and na(+)-ca(2+) exchanger on ca(2+) trigger flux in rabbit myocytes with realistic T-tubule geometries. Front Physiol. 2012; 3:351. Kekenes-Huskey PM, Cheng Y, Hake JE, Sachse FB, Bridge JH, Holst MJ, McCammon JA, McCulloch AD, Michailova AP. PMID: 23060801; PMCID: PMC3463892.
      View in: PubMed   Mentions: 18  
    121. Slow Calcium-Depolarization-Calcium waves may initiate fast local depolarization waves in ventricular tissue. Prog Biophys Mol Biol. 2012 Oct-Nov; 110(2-3):295-304. Tveito A, Lines GT, Edwards AG, Maleckar MM, Michailova A, Hake J, McCulloch A. PMID: 22841534; PMCID: PMC3484180.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    122. Improved discretisation and linearisation of active tension in strongly coupled cardiac electro-mechanics simulations. Comput Methods Biomech Biomed Engin. 2014; 17(6):604-15. Sundnes J, Wall S, Osnes H, Thorvaldsen T, McCulloch AD. PMID: 22800534; PMCID: PMC4230300.
      View in: PubMed   Mentions: 11     Fields:    
    123. A novel mechanism involving four-and-a-half LIM domain protein-1 and extracellular signal-regulated kinase-2 regulates titin phosphorylation and mechanics. J Biol Chem. 2012 Aug 24; 287(35):29273-84. Raskin A, Lange S, Banares K, Lyon RC, Zieseniss A, Lee LK, Yamazaki KG, Granzier HL, Gregorio CC, McCulloch AD, Omens JH, Sheikh F. PMID: 22778266; PMCID: PMC3436149.
      View in: PubMed   Mentions: 58     Fields:    Translation:HumansAnimalsCells
    124. An atlas-based geometry pipeline for cardiac Hermite model construction and diffusion tensor reorientation. Med Image Anal. 2012 Aug; 16(6):1130-41. Zhang Y, Liang X, Ma J, Jing Y, Gonzales MJ, Villongco C, Krishnamurthy A, Frank LR, Nigam V, Stark P, Narayan SM, McCulloch AD. PMID: 22841777; PMCID: PMC3443263.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    125. Southern California: a hotbed of biomedical engineering: nine bioengineers describe their research and why Southern California has the biotech market cornered. IEEE Pulse. 2012 Jul; 3(4):14-21. Berger T, Meng E, George S, Khoo M, Marmarelis V, McCulloch A, Cauwenberghs G, Ohno-Machado L, Schultz J, Johnson JP. PMID: 23008840.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    126. Modelling cardiac calcium sparks in a three-dimensional reconstruction of a calcium release unit. J Physiol. 2012 Sep 15; 590(18):4403-22. Hake J, Edwards AG, Yu Z, Kekenes-Huskey PM, Michailova AP, McCammon JA, Holst MJ, Hoshijima M, McCulloch AD. PMID: 22495592; PMCID: PMC3477749.
      View in: PubMed   Mentions: 52     Fields:    Translation:AnimalsCells
    127. Mouse and computational models link Mlc2v dephosphorylation to altered myosin kinetics in early cardiac disease. J Clin Invest. 2012 Apr; 122(4):1209-21. Sheikh F, Ouyang K, Campbell SG, Lyon RC, Chuang J, Fitzsimons D, Tangney J, Hidalgo CG, Chung CS, Cheng H, Dalton ND, Gu Y, Kasahara H, Ghassemian M, Omens JH, Peterson KL, Granzier HL, Moss RL, McCulloch AD, Chen J. PMID: 22426213; PMCID: PMC3314469.
      View in: PubMed   Mentions: 99     Fields:    Translation:AnimalsCells
    128. Statistical properties and robustness of biological controller-target networks. PLoS One. 2012; 7(1):e29374. Feala JD, Cortes J, Duxbury PM, McCulloch AD, Piermarocchi C, Paternostro G. PMID: 22235289; PMCID: PMC3250441.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    129. GPU acceleration of optical mapping algorithm for cardiac electrophysiology. Annu Int Conf IEEE Eng Med Biol Soc. 2012; 2012:1558-61. Meng P, Irturk A, Kastner R, McCulloch A, Omens J, Wright A. PMID: 23366201; PMCID: PMC3651586.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    130. A single strain-based growth law predicts concentric and eccentric cardiac growth during pressure and volume overload. Mech Res Commun. 2012 Jun 01; 42:40-50. Kerckhoffs RC, Omens J, McCulloch AD. PMID: 22639476; PMCID: PMC3358801.
      View in: PubMed   Mentions: 44  
    131. Early postmyocardial infarction survival in Murphy Roths Large mice is mediated by attenuated apoptosis and inflammation but depends on genetic background. Exp Physiol. 2012 Jan; 97(1):102-14. Hunt DL, Campbell PH, Zambon AC, Vranizan K, Evans SM, Kuo HC, Yamaguchi KD, Omens JH, McCulloch AD. PMID: 21967898; PMCID: PMC3253239.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    132. A nonlinear model of passive muscle viscosity. J Biomech Eng. 2011 Sep; 133(9):091007. Meyer GA, McCulloch AD, Lieber RL. PMID: 22010742; PMCID: PMC3705798.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    133. Multi-scale computational models of familial hypertrophic cardiomyopathy: genotype to phenotype. J R Soc Interface. 2011 Nov 07; 8(64):1550-61. Campbell SG, McCulloch AD. PMID: 21831889; PMCID: PMC3177620.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    134. Improvement in pump function with endocardial biventricular pacing increases with activation time at the left ventricular pacing site in failing canine hearts. Am J Physiol Heart Circ Physiol. 2011 Oct; 301(4):H1447-55. Howard EJ, Covell JW, Mulligan LJ, McCulloch AD, Omens JH, Kerckhoffs RC. PMID: 21784986; PMCID: PMC3197362.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    135. Patient-specific modeling of dyssynchronous heart failure: a case study. Prog Biophys Mol Biol. 2011 Oct; 107(1):147-55. Aguado-Sierra J, Krishnamurthy A, Villongco C, Chuang J, Howard E, Gonzales MJ, Omens J, Krummen DE, Narayan S, Kerckhoffs RC, McCulloch AD. PMID: 21763714; PMCID: PMC3190065.
      View in: PubMed   Mentions: 63     Fields:    Translation:Humans
    136. Minimum Information about a Cardiac Electrophysiology Experiment (MICEE): standardised reporting for model reproducibility, interoperability, and data sharing. Prog Biophys Mol Biol. 2011 Oct; 107(1):4-10. Quinn TA, Granite S, Allessie MA, Antzelevitch C, Bollensdorff C, Bub G, Burton RA, Cerbai E, Chen PS, Delmar M, Difrancesco D, Earm YE, Efimov IR, Egger M, Entcheva E, Fink M, Fischmeister R, Franz MR, Garny A, Giles WR, Hannes T, Harding SE, Hunter PJ, Iribe G, Jalife J, Johnson CR, Kass RS, Kodama I, Koren G, Lord P, Markhasin VS, Matsuoka S, McCulloch AD, Mirams GR, Morley GE, Nattel S, Noble D, Olesen SP, Panfilov AV, Trayanova NA, Ravens U, Richard S, Rosenbaum DS, Rudy Y, Sachs F, Sachse FB, Saint DA, Schotten U, Solovyova O, Taggart P, Tung L, Varró A, Volders PG, Wang K, Weiss JN, Wettwer E, White E, Wilders R, Winslow RL, Kohl P. PMID: 21745496; PMCID: PMC3190048.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansAnimals
    137. Defining candidate drug characteristics for Long-QT (LQT3) syndrome. Math Biosci Eng. 2011 Jul; 8(3):861-73. Tveito A, Lines GT, Li P, McCulloch A. PMID: 21675815.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    138. Policy needs and options for a common approach towards modelling and simulation of human physiology and diseases with a focus on the virtual physiological human. Stud Health Technol Inform. 2011; 170:49-82. Viceconti M, McCulloch AD. PMID: 21893899.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    139. Determination of three-dimensional ventricular strain distributions in gene-targeted mice using tagged MRI. Magn Reson Med. 2010 Nov; 64(5):1281-8. Chuang JS, Zemljic-Harpf A, Ross RS, Frank LR, McCulloch AD, Omens JH. PMID: 20981782; PMCID: PMC3272305.
      View in: PubMed   Mentions: 17     Fields:    Translation:Animals
    140. Numerical analysis of Ca2+ signaling in rat ventricular myocytes with realistic transverse-axial tubular geometry and inhibited sarcoplasmic reticulum. PLoS Comput Biol. 2010 Oct 28; 6(10):e1000972. Cheng Y, Yu Z, Hoshijima M, Holst MJ, McCulloch AD, McCammon JA, Michailova AP. PMID: 21060856; PMCID: PMC2965743.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    141. Coupling of adjacent tropomyosins enhances cross-bridge-mediated cooperative activation in a markov model of the cardiac thin filament. Biophys J. 2010 May 19; 98(10):2254-64. Campbell SG, Lionetti FV, Campbell KS, McCulloch AD. PMID: 20483334; PMCID: PMC2872217.
      View in: PubMed   Mentions: 53     Fields:    Translation:Cells
    142. Ventricular dilation and electrical dyssynchrony synergistically increase regional mechanical nonuniformity but not mechanical dyssynchrony: a computational model. Circ Heart Fail. 2010 Jul; 3(4):528-36. Kerckhoffs RC, Omens JH, McCulloch AD, Mulligan LJ. PMID: 20466849; PMCID: PMC3050711.
      View in: PubMed   Mentions: 30     Fields:    Translation:Humans
    143. Systems approaches and algorithms for discovery of combinatorial therapies. Wiley Interdiscip Rev Syst Biol Med. 2010 Mar-Apr; 2(2):181-193. Feala JD, Cortes J, Duxbury PM, Piermarocchi C, McCulloch AD, Paternostro G. PMID: 20836021.
      View in: PubMed   Mentions: 52     Fields:    Translation:HumansAnimals
    144. Cardiac myocyte force development during differentiation and maturation. Ann N Y Acad Sci. 2010 Feb; 1188:121-7. Jacot JG, Kita-Matsuo H, Wei KA, Chen HS, Omens JH, Mercola M, McCulloch AD. PMID: 20201894; PMCID: PMC2920416.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansAnimalsCells
    145. Metabolism as means for hypoxia adaptation: metabolic profiling and flux balance analysis. BMC Syst Biol. 2009 Sep 09; 3:91. Feala JD, Coquin L, Zhou D, Haddad GG, Paternostro G, McCulloch AD. PMID: 19740440; PMCID: PMC2749811.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    146. Hypertrophic gene expression induced by chronic stretch of excised mouse heart muscle. Mol Cell Biomech. 2009 Sep; 6(3):145-59. Raskin AM, Hoshijima M, Swanson E, McCulloch AD, Omens JH. PMID: 19670825; PMCID: PMC3272304.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    147. Lentiviral vectors and protocols for creation of stable hESC lines for fluorescent tracking and drug resistance selection of cardiomyocytes. PLoS One. 2009; 4(4):e5046. Kita-Matsuo H, Barcova M, Prigozhina N, Salomonis N, Wei K, Jacot JG, Nelson B, Spiering S, Haverslag R, Kim C, Talantova M, Bajpai R, Calzolari D, Terskikh A, McCulloch AD, Price JH, Conklin BR, Chen HS, Mercola M. PMID: 19352491; PMCID: PMC2662416.
      View in: PubMed   Mentions: 125     Fields:    Translation:HumansCells
    148. Multiscale modeling in rodent ventricular myocytes. IEEE Eng Med Biol Mag. 2009 Mar-Apr; 28(2):46-57. Lu S, Michailova A, Saucerman J, Cheng Y, Yu Z, Kaiser T, Li W, Bank R, Holst M, McCammon J, Hayashi T, Hoshijima M, Arzberger P, McCulloch A. PMID: 19349251; PMCID: PMC3197248.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    149. Effect of transmurally heterogeneous myocyte excitation-contraction coupling on canine left ventricular electromechanics. Exp Physiol. 2009 May; 94(5):541-52. Campbell SG, Howard E, Aguado-Sierra J, Coppola BA, Omens JH, Mulligan LJ, McCulloch AD, Kerckhoffs RC. PMID: 19251984; PMCID: PMC2744637.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    150. Multi-scale modeling of excitation-contraction coupling in the normal and failing heart. Annu Int Conf IEEE Eng Med Biol Soc. 2009; 2009:4281-2. Kerckhoffs RC, Campbell SG, Flaim SN, Howard EJ, Sierra-Aguado J, Mulligan LJ, McCulloch AD. PMID: 19963818; PMCID: PMC2896048.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    151. Search algorithms as a framework for the optimization of drug combinations. PLoS Comput Biol. 2008 Dec; 4(12):e1000249. Calzolari D, Bruschi S, Coquin L, Schofield J, Feala JD, Reed JC, McCulloch AD, Paternostro G. PMID: 19112483; PMCID: PMC2590660.
      View in: PubMed   Mentions: 40     Fields:    
    152. Metabolomic and flux-balance analysis of age-related decline of hypoxia tolerance in Drosophila muscle tissue. Mol Syst Biol. 2008; 4:233. Coquin L, Feala JD, McCulloch AD, Paternostro G. PMID: 19096360; PMCID: PMC2615305.
      View in: PubMed   Mentions: 27     Fields:    Translation:Animals
    153. An FHL1-containing complex within the cardiomyocyte sarcomere mediates hypertrophic biomechanical stress responses in mice. J Clin Invest. 2008 Dec; 118(12):3870-80. Sheikh F, Raskin A, Chu PH, Lange S, Domenighetti AA, Zheng M, Liang X, Zhang T, Yajima T, Gu Y, Dalton ND, Mahata SK, Dorn GW, Brown JH, Heller-Brown J, Peterson KL, Omens JH, McCulloch AD, Chen J. PMID: 19033658; PMCID: PMC2575833.
      View in: PubMed   Mentions: 134     Fields:    Translation:AnimalsCells
    154. Mechanisms of transmurally varying myocyte electromechanics in an integrated computational model. Philos Trans A Math Phys Eng Sci. 2008 Sep 28; 366(1879):3361-80. Campbell SG, Flaim SN, Leem CH, McCulloch AD. PMID: 18593662; PMCID: PMC2556206.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    155. Systems approach to understanding electromechanical activity in the human heart: a national heart, lung, and blood institute workshop summary. Circulation. 2008 Sep 09; 118(11):1202-11. Rudy Y, Ackerman MJ, Bers DM, Clancy CE, Houser SR, London B, McCulloch AD, Przywara DA, Rasmusson RL, Solaro RJ, Trayanova NA, Van Wagoner DR, Varró A, Weiss JN, Lathrop DA. PMID: 18779456; PMCID: PMC2908516.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansAnimals
    156. Coxsackievirus and adenovirus receptor (CAR) mediates atrioventricular-node function and connexin 45 localization in the murine heart. J Clin Invest. 2008 Aug; 118(8):2758-70. Lim BK, Xiong D, Dorner A, Youn TJ, Yung A, Liu TI, Gu Y, Dalton ND, Wright AT, Evans SM, Chen J, Peterson KL, McCulloch AD, Yajima T, Knowlton KU. PMID: 18636119; PMCID: PMC2467382.
      View in: PubMed   Mentions: 59     Fields:    Translation:HumansAnimalsCells
    157. Mechanisms of conduction slowing during myocardial stretch by ventricular volume loading in the rabbit. Am J Physiol Heart Circ Physiol. 2008 Sep; 295(3):H1270-H1278. Mills RW, Narayan SM, McCulloch AD. PMID: 18660447; PMCID: PMC2544493.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    158. Effects of biventricular pacing and scar size in a computational model of the failing heart with left bundle branch block. Med Image Anal. 2009 Apr; 13(2):362-9. Kerckhoffs RC, McCulloch AD, Omens JH, Mulligan LJ. PMID: 18675578; PMCID: PMC2796510.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimals
    159. Computational modeling for bedside application. Heart Fail Clin. 2008 Jul; 4(3):371-8. Kerckhoffs RC, Narayan SM, Omens JH, Mulligan LJ, McCulloch AD. PMID: 18598988; PMCID: PMC2518746.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    160. Substrate stiffness affects the functional maturation of neonatal rat ventricular myocytes. Biophys J. 2008 Oct; 95(7):3479-87. Jacot JG, McCulloch AD, Omens JH. PMID: 18586852; PMCID: PMC2547444.
      View in: PubMed   Mentions: 210     Fields:    Translation:AnimalsCells
    161. A myocardial lineage derives from Tbx18 epicardial cells. Nature. 2008 Jul 03; 454(7200):104-8. Cai CL, Martin JC, Sun Y, Cui L, Wang L, Ouyang K, Yang L, Bu L, Liang X, Zhang X, Stallcup WB, Denton CP, McCulloch A, Chen J, Evans SM. PMID: 18480752; PMCID: PMC5540369.
      View in: PubMed   Mentions: 401     Fields:    Translation:AnimalsCells
    162. Single nucleotide polymorphisms in human Paneth cell defensin A5 may confer susceptibility to inflammatory bowel disease in a New Zealand Caucasian population. Dig Liver Dis. 2008 Sep; 40(9):723-30. Ferguson LR, Browning BL, Huebner C, Petermann I, Shelling AN, Demmers P, McCulloch A, Gearry RB, Barclay ML, Philpott M. PMID: 18394979.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    163. Cardiac resynchronization: insight from experimental and computational models. Prog Biophys Mol Biol. 2008 Jun-Jul; 97(2-3):543-61. Kerckhoffs RC, Lumens J, Vernooy K, Omens JH, Mulligan LJ, Delhaas T, Arts T, McCulloch AD, Prinzen FW. PMID: 18417196; PMCID: PMC2676869.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCells
    164. Discovering regulators of the Drosophila cardiac hypoxia response using automated phenotyping technology. Ann N Y Acad Sci. 2008 Mar; 1123:169-77. Feala JD, Omens JH, Paternostro G, McCulloch AD. PMID: 18375589.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    165. Effects of biglycan deficiency on myocardial infarct structure and mechanics. Mol Cell Biomech. 2008 Mar; 5(1):27-35. Campbell PH, Hunt DL, Jones Y, Harwood F, Amiel D, Omens JH, McCulloch AD. PMID: 18524244; PMCID: PMC2679639.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    166. Effects of Mg2+, pH and PCr on cardiac excitation-metabolic coupling. Magnes Res. 2008 Mar; 21(1):16-28. Michailova A, McCulloch AD. PMID: 18557130.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    167. Cell cultures as models of cardiac mechanoelectric feedback. Prog Biophys Mol Biol. 2008 Jun-Jul; 97(2-3):367-82. Zhang Y, Sekar RB, McCulloch AD, Tung L. PMID: 18384846; PMCID: PMC2733372.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    168. The role of mechanoelectric feedback in vulnerability to electric shock. Prog Biophys Mol Biol. 2008 Jun-Jul; 97(2-3):461-78. Li W, Gurev V, McCulloch AD, Trayanova NA. PMID: 18374394; PMCID: PMC2517254.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    169. Acetylcholine-induced shortening of the epicardial action potential duration may increase repolarization gradients and LQT3 arrhythmic risk. J Electrocardiol. 2007 Nov-Dec; 40(6 Suppl):S66-9. Flaim SN, McCulloch AD. PMID: 17993332.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    170. Cardiac-myocyte-specific excision of the vinculin gene disrupts cellular junctions, causing sudden death or dilated cardiomyopathy. Mol Cell Biol. 2007 Nov; 27(21):7522-37. Zemljic-Harpf AE, Miller JC, Henderson SA, Wright AT, Manso AM, Elsherif L, Dalton ND, Thor AK, Perkins GA, McCulloch AD, Ross RS. PMID: 17785437; PMCID: PMC2169049.
      View in: PubMed   Mentions: 102     Fields:    Translation:AnimalsCells
    171. Integrating metabolomics and phenomics with systems models of cardiac hypoxia. Prog Biophys Mol Biol. 2008 Jan-Apr; 96(1-3):209-25. Feala JD, Coquin L, Paternostro G, McCulloch AD. PMID: 17870149.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimals
    172. The cobalamin precursor cobinamide detoxifies nitroprusside-generated cyanide. Exp Biol Med (Maywood). 2007 Jun; 232(6):789-98. Broderick KE, Balasubramanian M, Chan A, Potluri P, Feala J, Belke DD, McCulloch A, Sharma VS, Pilz RB, Bigby TD, Boss GR. PMID: 17526771.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    173. Asynchrony of ventricular activation affects magnitude and timing of fiber stretch in late-activated regions of the canine heart. Am J Physiol Heart Circ Physiol. 2007 Jul; 293(1):H754-61. Coppola BA, Covell JW, McCulloch AD, Omens JH. PMID: 17449547; PMCID: PMC3328414.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    174. Flexibility in energy metabolism supports hypoxia tolerance in Drosophila flight muscle: metabolomic and computational systems analysis. Mol Syst Biol. 2007; 3:99. Feala JD, Coquin L, McCulloch AD, Paternostro G. PMID: 17437024; PMCID: PMC1865581.
      View in: PubMed   Mentions: 36     Fields:    Translation:Animals
    175. High-resolution longitudinal MRI of the transition to heart failure. Magn Reson Med. 2007 Apr; 57(4):714-20. Costandi PN, McCulloch AD, Omens JH, Frank LR. PMID: 17390366; PMCID: PMC4482467.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    176. Modeling transmural heterogeneity of K(ATP) current in rabbit ventricular myocytes. Am J Physiol Cell Physiol. 2007 Aug; 293(2):C542-57. Michailova A, Lorentz W, McCulloch A. PMID: 17329404.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    177. Arrhythmogenic consequences of Na+ channel mutations in the transmurally heterogeneous mammalian left ventricle: analysis of the I1768V SCN5A mutation. Heart Rhythm. 2007 Jun; 4(6):768-78. Flaim SN, Giles WR, McCulloch AD. PMID: 17556201.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    178. Coupling of a 3D finite element model of cardiac ventricular mechanics to lumped systems models of the systemic and pulmonic circulation. Ann Biomed Eng. 2007 Jan; 35(1):1-18. Kerckhoffs RC, Neal ML, Gu Q, Bassingthwaighte JB, Omens JH, McCulloch AD. PMID: 17111210; PMCID: PMC2872168.
      View in: PubMed   Mentions: 109     Fields:    Translation:Animals
    179. Cardiac beta-adrenergic signaling: from subcellular microdomains to heart failure. Ann N Y Acad Sci. 2006 Oct; 1080:348-61. Saucerman JJ, McCulloch AD. PMID: 17132794.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCells
    180. The nitric oxide scavenger cobinamide profoundly improves survival in a Drosophila melanogaster model of bacterial sepsis. FASEB J. 2006 Sep; 20(11):1865-73. Broderick KE, Feala J, McCulloch A, Paternostro G, Sharma VS, Pilz RB, Boss GR. PMID: 16940158.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    181. Systems analysis of PKA-mediated phosphorylation gradients in live cardiac myocytes. Proc Natl Acad Sci U S A. 2006 Aug 22; 103(34):12923-8. Saucerman JJ, Zhang J, Martin JC, Peng LX, Stenbit AE, Tsien RY, McCulloch AD. PMID: 16905651; PMCID: PMC1568947.
      View in: PubMed   Mentions: 75     Fields:    Translation:AnimalsCells
    182. Role of diastolic properties in the transition to failure in a mouse model of the cardiac dilatation. Am J Physiol Heart Circ Physiol. 2006 Dec; 291(6):H2971-9. Costandi PN, Frank LR, McCulloch AD, Omens JH. PMID: 16861693; PMCID: PMC3334322.
      View in: PubMed   Mentions: 14     Fields:    Translation:Animals
    183. Contributions of sustained INa and IKv43 to transmural heterogeneity of early repolarization and arrhythmogenesis in canine left ventricular myocytes. Am J Physiol Heart Circ Physiol. 2006 Dec; 291(6):H2617-29. Flaim SN, Giles WR, McCulloch AD. PMID: 16829642.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    184. Myocyte shearing, myocardial sheets, and microtubules. Circ Res. 2006 Jan 06; 98(1):1-3. McCulloch AD, Omens JH. PMID: 16397149.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    185. Micropatterned cell cultures on elastic membranes as an in vitro model of myocardium. Nat Protoc. 2006; 1(3):1379-91. Camelliti P, Gallagher JO, Kohl P, McCulloch AD. PMID: 17406425.
      View in: PubMed   Mentions: 39     Fields:    Translation:Animals
    186. Chronotropic response of cultured neonatal rat ventricular myocytes to short-term fluid shear. Cell Biochem Biophys. 2006; 46(2):113-22. Lorenzen-Schmidt I, Schmid-Schönbein GW, Giles WR, McCulloch AD, Chien S, Omens JH. PMID: 17012753; PMCID: PMC3310206.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    187. An ionic model of stretch-activated and stretch-modulated currents in rabbit ventricular myocytes. Europace. 2005 Sep; 7 Suppl 2:128-34. Healy SN, McCulloch AD. PMID: 16102510.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    188. Young MLP deficient mice show diastolic dysfunction before the onset of dilated cardiomyopathy. J Mol Cell Cardiol. 2005 Aug; 39(2):241-50. Lorenzen-Schmidt I, Stuyvers BD, ter Keurs HE, Date MO, Hoshijima M, Chien KR, McCulloch AD, Omens JH. PMID: 15978612; PMCID: PMC4484861.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    189. Cell proliferation rates in an artificial tissue-engineered environment. Cell Prolif. 2005 Aug; 38(4):215-21. Sarraf CE, Harris AB, McCulloch AD, Eastwood M. PMID: 16098181; PMCID: PMC6496514.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    190. Deficiency of actinin-associated LIM protein alters regional right ventricular function and hypertrophic remodeling. Ann Biomed Eng. 2005 Jul; 33(7):888-96. Lorenzen-Schmidt I, McCulloch AD, Omens JH. PMID: 16060528; PMCID: PMC4482468.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    191. Microstructured cocultures of cardiac myocytes and fibroblasts: a two-dimensional in vitro model of cardiac tissue. Microsc Microanal. 2005 Jun; 11(3):249-59. Camelliti P, McCulloch AD, Kohl P. PMID: 16060978.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    192. Cardiac systems biology. Ann N Y Acad Sci. 2005 Jun; 1047:283-95. McCulloch AD, Paternostro G. PMID: 16093504.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    193. A role for decorin in the remodeling of myocardial infarction. Matrix Biol. 2005 Jun; 24(4):313-24. Weis SM, Zimmerman SD, Shah M, Covell JW, Omens JH, Ross J, Dalton N, Jones Y, Reed CC, Iozzo RV, McCulloch AD. PMID: 15949932.
      View in: PubMed   Mentions: 52     Fields:    Translation:Animals
    194. Modeling regulation of cardiac KATP and L-type Ca2+ currents by ATP, ADP, and Mg2+. Biophys J. 2005 Mar; 88(3):2234-49. Michailova A, Saucerman J, Belik ME, McCulloch AD. PMID: 15738467; PMCID: PMC1305273.
      View in: PubMed   Mentions: 15     Fields:    Translation:Cells
    195. Functionally and structurally integrated computational modeling of ventricular physiology. Jpn J Physiol. 2004 Dec; 54(6):531-9. McCulloch AD. PMID: 15760485.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimals
    196. Nonhomogeneous deformation in the anterior leaflet of the mitral valve. Ann Biomed Eng. 2004 Dec; 32(12):1599-606. Chen L, McCulloch AD, May-Newman K. PMID: 15675673.
      View in: PubMed   Mentions: 9     Fields:    Translation:Animals
    197. Proarrhythmic consequences of a KCNQ1 AKAP-binding domain mutation: computational models of whole cells and heterogeneous tissue. Circ Res. 2004 Dec 10; 95(12):1216-24. Saucerman JJ, Healy SN, Belik ME, Puglisi JL, McCulloch AD. PMID: 15528464.
      View in: PubMed   Mentions: 62     Fields:    Translation:AnimalsCells
    198. Left ventricular form and function: scientific priorities and strategic planning for development of new views of disease. Circulation. 2004 Oct 05; 110(14):e333-6. Buckberg GD, Weisfeldt ML, Ballester M, Beyar R, Burkhoff D, Coghlan HC, Doyle M, Epstein ND, Gharib M, Ideker RE, Ingels NB, LeWinter MM, McCulloch AD, Pohost GM, Reinlib LJ, Sahn DJ, Sopko G, Spinale FG, Spotnitz HM, Torrent-Guasp F, Shapiro EP. PMID: 15466651.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    199. Effects of magnesium on cardiac excitation-contraction coupling. J Am Coll Nutr. 2004 Oct; 23(5):514S-517S. Michailova AP, Belik ME, McCulloch AD. PMID: 15466954.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    200. A more efficient search strategy for aging genes based on connectivity. Bioinformatics. 2005 Feb 01; 21(3):338-48. Ferrarini L, Bertelli L, Feala J, McCulloch AD, Paternostro G. PMID: 15347572.
      View in: PubMed   Mentions: 15     Fields:    Translation:Cells
    201. Mechanistic systems models of cell signaling networks: a case study of myocyte adrenergic regulation. Prog Biophys Mol Biol. 2004 Jun-Jul; 85(2-3):261-78. Saucerman JJ, McCulloch AD. PMID: 15142747.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    202. Structural and functional roles of desmin in mouse skeletal muscle during passive deformation. Biophys J. 2004 May; 86(5):2993-3008. Shah SB, Davis J, Weisleder N, Kostavassili I, McCulloch AD, Ralston E, Capetanaki Y, Lieber RL. PMID: 15111414; PMCID: PMC1304166.
      View in: PubMed   Mentions: 59     Fields:    Translation:AnimalsCells
    203. New multi-cue bioreactor for tissue engineering of tubular cardiovascular samples under physiological conditions. Tissue Eng. 2004 Mar-Apr; 10(3-4):565-73. McCulloch AD, Harris AB, Sarraf CE, Eastwood M. PMID: 15165473.
      View in: PubMed   Mentions: 7     Fields:    
    204. Relationship between regional shortening and asynchronous electrical activation in a three-dimensional model of ventricular electromechanics. J Cardiovasc Electrophysiol. 2003 Oct; 14(10 Suppl):S196-202. Usyk TP, McCulloch AD. PMID: 14760924.
      View in: PubMed   Mentions: 31     Fields:    Translation:AnimalsCells
    205. Heart valve and arterial tissue engineering. Cell Prolif. 2003 Oct; 36(5):241-54. Sarraf CE, Harris AB, McCulloch AD, Eastwood M. PMID: 14521518; PMCID: PMC6496809.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    206. Modeling beta-adrenergic control of cardiac myocyte contractility in silico. J Biol Chem. 2003 Nov 28; 278(48):47997-8003. Saucerman JJ, Brunton LL, Michailova AP, McCulloch AD. PMID: 12972422.
      View in: PubMed   Mentions: 106     Fields:    Translation:HumansAnimalsCells
    207. Ventricular filling slows epicardial conduction and increases action potential duration in an optical mapping study of the isolated rabbit heart. J Cardiovasc Electrophysiol. 2003 Jul; 14(7):739-49. Sung D, Mills RW, Schettler J, Narayan SM, Omens JH, McCulloch AD. PMID: 12930255.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    208. Complex distributions of residual stress and strain in the mouse left ventricle: experimental and theoretical models. Biomech Model Mechanobiol. 2003 Apr; 1(4):267-77. Omens JH, McCulloch AD, Criscione JC. PMID: 14586695.
      View in: PubMed   Mentions: 14     Fields:    Translation:Animals
    209. Anisotropic stretch-induced hypertrophy in neonatal ventricular myocytes micropatterned on deformable elastomers. Biotechnol Bioeng. 2003 Mar 05; 81(5):578-87. Gopalan SM, Flaim C, Bhatia SN, Hoshijima M, Knoell R, Chien KR, Omens JH, McCulloch AD. PMID: 12514807.
      View in: PubMed   Mentions: 62     Fields:    Translation:AnimalsCells
    210. Electromechanical model of cardiac resynchronization in the dilated failing heart with left bundle branch block. J Electrocardiol. 2003; 36 Suppl:57-61. Usyk TP, McCulloch AD. PMID: 14716593.
      View in: PubMed   Mentions: 18     Fields:    Translation:Animals
    211. The cardiac mechanical stretch sensor machinery involves a Z disc complex that is defective in a subset of human dilated cardiomyopathy. Cell. 2002 Dec 27; 111(7):943-55. Knöll R, Hoshijima M, Hoffman HM, Person V, Lorenzen-Schmidt I, Bang ML, Hayashi T, Shiga N, Yasukawa H, Schaper W, McKenna W, Yokoyama M, Schork NJ, Omens JH, McCulloch AD, Kimura A, Gregorio CC, Poller W, Schaper J, Schultheiss HP, Chien KR. PMID: 12507422.
      View in: PubMed   Mentions: 290     Fields:    Translation:HumansAnimalsCells
    212. Glycated collagen cross-linking alters cardiac mechanics in volume-overload hypertrophy. Am J Physiol Heart Circ Physiol. 2003 Apr; 284(4):H1277-84. Herrmann KL, McCulloch AD, Omens JH. PMID: 12595292; PMCID: PMC3325795.
      View in: PubMed   Mentions: 31     Fields:    Translation:Animals
    213. Muscle LIM protein deficiency leads to alterations in passive ventricular mechanics. Am J Physiol Heart Circ Physiol. 2002 Feb; 282(2):H680-7. Omens JH, Usyk TP, Li Z, McCulloch AD. PMID: 11788418.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    214. Integrative biological modelling in silico. Novartis Found Symp. 2002; 247:4-19; discussion 20-5, 84-90, 244-52. McCulloch AD, Huber G. PMID: 12539946.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    215. Tissue engineering of biological cardiovascular system surrogates. Heart Lung Circ. 2002; 11(3):142-50; discussion 151. Sarraf CE, Harris AB, McCulloch AD, Eastwood M. PMID: 16352087.
      View in: PubMed   Mentions: 5     Fields:    
    216. In vivo finite element model-based image analysis of pacemaker lead mechanics. Med Image Anal. 2001 Dec; 5(4):255-70. Baxter WW, McCulloch AD. PMID: 11731305.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    217. Phase shifting prior to spatial filtering enhances optical recordings of cardiac action potential propagation. Ann Biomed Eng. 2001 Oct; 29(10):854-61. Sung D, Mills R, McCulloch AD. PMID: 11764316.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    218. Oesophageal morphometry and residual strain in a mouse model of osteogenesis imperfecta. Neurogastroenterol Motil. 2001 Oct; 13(5):457-64. Gregersen H, Weis SM, McCulloch AD. PMID: 11696107.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    219. Model study of ATP and ADP buffering, transport of Ca(2+) and Mg(2+), and regulation of ion pumps in ventricular myocyte. Biophys J. 2001 Aug; 81(2):614-29. Michailova A, McCulloch A. PMID: 11463611; PMCID: PMC1301539.
      View in: PubMed   Mentions: 26     Fields:    Translation:Cells
    220. Regional septal dysfunction in a three-dimensional computational model of focal myofiber disarray. Am J Physiol Heart Circ Physiol. 2001 Aug; 281(2):H506-14. Usyk TP, Omens JH, McCulloch AD. PMID: 11454551.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    221. Transmural distribution of three-dimensional systolic strains in stunned myocardium. Circulation. 2001 Jul 17; 104(3):336-41. Mazhari R, Omens JH, Pavelec RS, Covell JW, McCulloch AD. PMID: 11457754.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    222. Age-associated cardiac dysfunction in Drosophila melanogaster. Circ Res. 2001 May 25; 88(10):1053-8. Paternostro G, Vignola C, Bartsch DU, Omens JH, McCulloch AD, Reed JC. PMID: 11375275.
      View in: PubMed   Mentions: 49     Fields:    Translation:Animals
    223. Relating myocardial laminar architecture to shear strain and muscle fiber orientation. Am J Physiol Heart Circ Physiol. 2001 May; 280(5):H2222-9. Arts T, Costa KD, Covell JW, McCulloch AD. PMID: 11299225.
      View in: PubMed   Mentions: 42     Fields:    Translation:AnimalsCells
    224. Flux-balance analysis of mitochondrial energy metabolism: consequences of systemic stoichiometric constraints. Am J Physiol Regul Integr Comp Physiol. 2001 Mar; 280(3):R695-704. Ramakrishna R, Edwards JS, McCulloch A, Palsson BO. PMID: 11171647.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansCells
    225. Regional heterogeneity of function in nonischemic dilated cardiomyopathy. Cardiovasc Res. 2001 Feb 01; 49(2):308-18. Young AA, Dokos S, Powell KA, Sturm B, McCulloch AD, Starling RC, McCarthy PM, White RD. PMID: 11164841.
      View in: PubMed   Mentions: 26     Fields:    Translation:Humans
    226. Myocardial mechanics and collagen structure in the osteogenesis imperfecta murine (oim). Circ Res. 2000 Oct 13; 87(8):663-9. Weis SM, Emery JL, Becker KD, McBride DJ, Omens JH, McCulloch AD. PMID: 11029401.
      View in: PubMed   Mentions: 54     Fields:    Translation:AnimalsCells
    227. Model-based analysis of optically mapped epicardial activation patterns and conduction velocity. Ann Biomed Eng. 2000 Sep; 28(9):1085-92. Sung D, Omens JH, McCulloch AD. PMID: 11132192.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    228. Modeling the human cardiome in silico. J Nucl Cardiol. 2000 Sep-Oct; 7(5):496-9. McCulloch AD. PMID: 11083199.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    229. Integrative models for understanding the structural basis of regional mechanical dysfunction in ischemic myocardium. Ann Biomed Eng. 2000 Aug; 28(8):979-90. Mazhari R, McCulloch AD. PMID: 11144683.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    230. Structural basis of regional dysfunction in acutely ischemic myocardium. Cardiovasc Res. 2000 Aug; 47(2):284-93. Mazhari R, Omens JH, Covell JW, McCulloch AD. PMID: 10946065.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    231. Three-dimensional stress and strain in passive rabbit left ventricle: a model study. Ann Biomed Eng. 2000 Jul; 28(7):781-92. Vetter FJ, McCulloch AD. PMID: 11016415.
      View in: PubMed   Mentions: 25     Fields:    Translation:Animals
    232. Regional dysfunction correlates with myofiber disarray in transgenic mice with ventricular expression of ras. Am J Physiol Heart Circ Physiol. 2000 Mar; 278(3):H898-906. Karlon WJ, McCulloch AD, Covell JW, Hunter JJ, Omens JH. PMID: 10710359; PMCID: PMC3328188.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    233. Imaging three-dimensional cardiac function. Annu Rev Biomed Eng. 2000; 2:431-56. O'Dell WG, McCulloch AD. PMID: 11701519.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    234. Measurement of orientation and distribution of cellular alignment and cytoskeletal organization. Ann Biomed Eng. 1999 Nov-Dec; 27(6):712-20. Karlon WJ, Hsu PP, Li S, Chien S, McCulloch AD, Omens JH. PMID: 10625144.
      View in: PubMed   Mentions: 48     Fields:    Translation:AnimalsCells
    235. Differential responses of adult cardiac fibroblasts to in vitro biaxial strain patterns. J Mol Cell Cardiol. 1999 Oct; 31(10):1833-43. Lee AA, Delhaas T, McCulloch AD, Villarreal FJ. PMID: 10525421.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    236. Laminar fiber architecture and three-dimensional systolic mechanics in canine ventricular myocardium. Am J Physiol. 1999 02; 276(2):H595-607. Costa KD, Takayama Y, McCulloch AD, Covell JW. PMID: 9950861.
      View in: PubMed   Mentions: 106     Fields:    Translation:AnimalsCells
    237. Residual strain in ischemic ventricular myocardium. J Biomech Eng. 1998 Dec; 120(6):710-4. Summerour SR, Emery JL, Fazeli B, Omens JH, McCulloch AD. PMID: 10412453.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    238. Left ventricular geometric remodeling and residual stress in the rat heart. J Biomech Eng. 1998 Dec; 120(6):715-9. Omens JH, Vaplon SM, Fazeli B, McCulloch AD. PMID: 10412454.
      View in: PubMed   Mentions: 11     Fields:    Translation:Animals
    239. Automated measurement of myofiber disarray in transgenic mice with ventricular expression of ras. Anat Rec. 1998 12; 252(4):612-25. Karlon WJ, Covell JW, McCulloch AD, Hunter JJ, Omens JH. PMID: 9845212.
      View in: PubMed   Mentions: 62     Fields:    Translation:AnimalsCells
    240. Regional myocardial perfusion and mechanics: a model-based method of analysis. Ann Biomed Eng. 1998 Sep-Oct; 26(5):743-55. Mazhari R, Omens JH, Waldman LK, McCulloch AD. PMID: 9779946.
      View in: PubMed   Mentions: 11     Fields:    Translation:Animals
    241. History-dependent mechanical behavior of guinea-pig small intestine. Ann Biomed Eng. 1998 Sep-Oct; 26(5):850-8. Gregersen H, Emery JL, McCulloch AD. PMID: 9779958.
      View in: PubMed   Mentions: 11     Fields:    Translation:Animals
    242. Mechanisms of length history-dependent tension in an ionic model of the cardiac myocyte. Am J Physiol. 1998 03; 274(3):H1032-40. Bluhm WF, Lew WY, Garfinkel A, McCulloch AD. PMID: 9530218.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    243. Flow-function relations during graded coronary occlusions in the dog: effects of transmural location and segment orientation. Cardiovasc Res. 1998 Mar; 37(3):636-45. McCulloch AD, Sung D, Wilson JM, Pavelec RS, Omens JH. PMID: 9659447.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    244. Anterior-posterior strain variation in normally hydrated and swollen rabbit cornea. Invest Ophthalmol Vis Sci. 1998 Feb; 39(2):253-62. Hennighausen H, Feldman ST, Bille JF, McCulloch AD. PMID: 9477981.
      View in: PubMed   Mentions: 15     Fields:    Translation:Animals
    245. Computational biology of the heart: from structure to function. Prog Biophys Mol Biol. 1998; 69(2-3):153-5. McCulloch A, Bassingthwaighte J, Hunter P, Noble D. PMID: 9785936; PMCID: PMC4128782.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimals
    246. Three-dimensional analysis of regional cardiac function: a model of rabbit ventricular anatomy. Prog Biophys Mol Biol. 1998; 69(2-3):157-83. Vetter FJ, McCulloch AD. PMID: 9785937.
      View in: PubMed   Mentions: 83     Fields:    Translation:HumansAnimals
    247. Modelling the mechanical properties of cardiac muscle. Prog Biophys Mol Biol. 1998; 69(2-3):289-331. Hunter PJ, McCulloch AD, ter Keurs HE. PMID: 9785944.
      View in: PubMed   Mentions: 85     Fields:    Translation:AnimalsCells
    248. Homogenization modeling for the mechanics of perfused myocardium. Prog Biophys Mol Biol. 1998; 69(2-3):463-81. May-Newman K, McCulloch AD. PMID: 9785951.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimals
    249. Cellular mechanisms for the slow phase of the Frank-Starling response. J Electrocardiol. 1998; 31 Suppl:13-22. Bluhm WF, Sung D, Lew WY, Garfinkel A, McCulloch AD. PMID: 9988000.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    250. Three-dimensional residual strain in midanterior canine left ventricle. Am J Physiol. 1997 10; 273(4):H1968-76. Costa KD, May-Newman K, Farr D, O'Dell WG, McCulloch AD, Omens JH. PMID: 9362268; PMCID: PMC3343007.
      View in: PubMed   Mentions: 20     Fields:    Translation:Animals
    251. Microstructural model of perimysial collagen fibers for resting myocardial mechanics during ventricular filling. Am J Physiol. 1997 Sep; 273(3 Pt 2):H1576-86. MacKenna DA, Vaplon SM, McCulloch AD. PMID: 9321852.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    252. Biaxial mechanics of the passively overstretched left ventricle. Am J Physiol. 1997 May; 272(5 Pt 2):H2299-305. Emery JL, Omens JH, McCulloch AD. PMID: 9176298.
      View in: PubMed   Mentions: 9     Fields:    Translation:Animals
    253. Strain softening in rat left ventricular myocardium. J Biomech Eng. 1997 Feb; 119(1):6-12. Emery JL, Omens JH, McCulloch AD. PMID: 9083843.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    254. Multiaxial myocardial mechanics and extracellular matrix remodeling: mechanochemical regulation of cardiac fibroblast function. Adv Exp Med Biol. 1997; 430:227-40. Lee AA, McCulloch AD. PMID: 9330732.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    255. Anterior and posterior left ventricular sarcomere lengths behave similarly during ejection. Am J Physiol. 1997 Jan; 272(1 Pt 2):H469-77. Guccione JM, O'Dell WG, McCulloch AD, Hunter WC. PMID: 9038969.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    256. A three-dimensional finite element method for large elastic deformations of ventricular myocardium: I--Cylindrical and spherical polar coordinates. J Biomech Eng. 1996 Nov; 118(4):452-63. Costa KD, Hunter PJ, Rogers JM, Guccione JM, Waldman LK, McCulloch AD. PMID: 8950648.
      View in: PubMed   Mentions: 14     Fields:    Translation:Animals
    257. A three-dimensional finite element method for large elastic deformations of ventricular myocardium: II--Prolate spheroidal coordinates. J Biomech Eng. 1996 Nov; 118(4):464-72. Costa KD, Hunter PJ, Wayne JS, Waldman LK, Guccione JM, McCulloch AD. PMID: 8950649.
      View in: PubMed   Mentions: 23     Fields:    Translation:Animals
    258. An equibiaxial strain system for cultured cells. Am J Physiol. 1996 Oct; 271(4 Pt 1):C1400-8. Lee AA, Delhaas T, Waldman LK, MacKenna DA, Villarreal FJ, McCulloch AD. PMID: 8897847.
      View in: PubMed   Mentions: 40     Fields:    Translation:AnimalsCells
    259. Transmural changes in stress-free myocyte morphology during pressure overload hypertrophy in the rat. J Mol Cell Cardiol. 1996 Sep; 28(9):1975-83. Omens JH, Rodriguez EK, McCulloch AD. PMID: 8899556.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    260. Comparison of two techniques for measuring two-dimensional strain in rat left ventricles. Am J Physiol. 1996 Sep; 271(3 Pt 2):H1256-61. Omens JH, Farr DD, McCulloch AD, Waldman LK. PMID: 8853366.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    261. Distributed mechanics of the canine right ventricle: effects of varying preload. J Biomech. 1996 Mar; 29(3):373-81. Waldman LK, Allen JJ, Pavelec RS, McCulloch AD. PMID: 8850643.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    262. Transmural distribution of capillary morphology as a function of coronary perfusion pressure in the resting canine heart. Microvasc Res. 1995 Nov; 50(3):381-96. May-Newman K, Mathieu-Costello O, Omens JH, Klumb K, McCulloch AD. PMID: 8583952.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    263. Angiotensin II stimulates the autocrine production of transforming growth factor-beta 1 in adult rat cardiac fibroblasts. J Mol Cell Cardiol. 1995 Oct; 27(10):2347-57. Lee AA, Dillmann WH, McCulloch AD, Villarreal FJ. PMID: 8576949.
      View in: PubMed   Mentions: 61     Fields:    Translation:AnimalsCells
    264. Finite element stress analysis of left ventricular mechanics in the beating dog heart. J Biomech. 1995 Oct; 28(10):1167-77. Guccione JM, Costa KD, McCulloch AD. PMID: 8550635.
      View in: PubMed   Mentions: 84     Fields:    Translation:AnimalsCells
    265. Active force in rabbit ventricular myocytes. J Biomech. 1995 Sep; 28(9):1119-22. Bluhm WF, McCulloch AD, Lew WY. PMID: 7559682.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    266. Gradients of epicardial strain across the perfusion boundary during acute myocardial ischemia. Am J Physiol. 1994 Dec; 267(6 Pt 2):H2348-62. Van Leuven SL, Waldman LK, McCulloch AD, Covell JW. PMID: 7810735.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    267. A collocation--Galerkin finite element model of cardiac action potential propagation. IEEE Trans Biomed Eng. 1994 Aug; 41(8):743-57. Rogers JM, McCulloch AD. PMID: 7927397.
      View in: PubMed   Mentions: 45     Fields:    Translation:Humans
    268. Nonuniform muscle fiber orientation causes spiral wave drift in a finite element model of cardiac action potential propagation. J Cardiovasc Electrophysiol. 1994 Jun; 5(6):496-509. Rogers JM, McCulloch AD. PMID: 8087294.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    269. Three-dimensional transmural mechanical interaction between the coronary vasculature and passive myocardium in the dog. Circ Res. 1994 Jun; 74(6):1166-78. May-Newman K, Omens JH, Pavelec RS, McCulloch AD. PMID: 8187283.
      View in: PubMed   Mentions: 15     Fields:    Translation:Animals
    270. Stress-dependent finite growth in soft elastic tissues. J Biomech. 1994 Apr; 27(4):455-67. Rodriguez EK, Hoger A, McCulloch AD. PMID: 8188726.
      View in: PubMed   Mentions: 278     Fields:    Translation:Humans
    271. Contribution of collagen matrix to passive left ventricular mechanics in isolated rat hearts. Am J Physiol. 1994 Mar; 266(3 Pt 2):H1007-18. MacKenna DA, Omens JH, McCulloch AD, Covell JW. PMID: 8160804.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    272. Nonhomogeneous ventricular wall strain: analysis of errors and accuracy. J Biomech Eng. 1993 Nov; 115(4B):497-502. Waldman LK, McCulloch AD. PMID: 8302031.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    273. Measurement of strain and analysis of stress in resting rat left ventricular myocardium. J Biomech. 1993 Jun; 26(6):665-76. Omens JH, MacKenna DA, McCulloch AD. PMID: 8514812.
      View in: PubMed   Mentions: 38     Fields:    Translation:Animals
    274. Effect of residual stress on transmural sarcomere length distributions in rat left ventricle. Am J Physiol. 1993 Apr; 264(4 Pt 2):H1048-56. Rodriguez EK, Omens JH, Waldman LK, McCulloch AD. PMID: 8476082.
      View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
    275. Mechanics of active contraction in cardiac muscle: Part I--Constitutive relations for fiber stress that describe deactivation. J Biomech Eng. 1993 Feb; 115(1):72-81. Guccione JM, McCulloch AD. PMID: 8445901.
      View in: PubMed   Mentions: 56     Fields:    Translation:Cells
    276. Mechanics of active contraction in cardiac muscle: Part II--Cylindrical models of the systolic left ventricle. J Biomech Eng. 1993 Feb; 115(1):82-90. Guccione JM, Waldman LK, McCulloch AD. PMID: 8445902.
      View in: PubMed   Mentions: 80     Fields:    Translation:AnimalsCells
    277. Nonhomogeneous analysis of epicardial strain distributions during acute myocardial ischemia in the dog. J Biomech. 1993 Jan; 26(1):19-35. Hashima AR, Young AA, McCulloch AD, Waldman LK. PMID: 8423166.
      View in: PubMed   Mentions: 14     Fields:    Translation:Animals
    278. Mechanical effects of coronary perfusion in the passive canine left ventricle. Am J Physiol. 1992 Feb; 262(2 Pt 2):H523-30. McCulloch AD, Hunter PJ, Smaill BH. PMID: 1539711.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    279. Large-scale finite element analysis of the beating heart. Crit Rev Biomed Eng. 1992; 20(5-6):427-49. McCulloch A, Waldman L, Rogers J, Guccione J. PMID: 1486784.
      View in: PubMed   Mentions: 26     Fields:    Translation:Animals
    280. Transmural distribution of three-dimensional strain in the isolated arrested canine left ventricle. Am J Physiol. 1991 Sep; 261(3 Pt 2):H918-28. Omens JH, May KD, McCulloch AD. PMID: 1887936.
      View in: PubMed   Mentions: 21     Fields:    Translation:Animals
    281. Passive material properties of intact ventricular myocardium determined from a cylindrical model. J Biomech Eng. 1991 Feb; 113(1):42-55. Guccione JM, McCulloch AD, Waldman LK. PMID: 2020175.
      View in: PubMed   Mentions: 152     Fields:    Translation:Animals
    282. Non-homogeneous analysis of three-dimensional transmural finite deformation in canine ventricular myocardium. J Biomech. 1991; 24(7):539-48. McCulloch AD, Omens JH. PMID: 1880138.
      View in: PubMed   Mentions: 15     Fields:    Translation:Animals
    283. Regional left ventricular epicardial deformation in the passive dog heart. Circ Res. 1989 Apr; 64(4):721-33. McCulloch AD, Smaill BH, Hunter PJ. PMID: 2702734.
      View in: PubMed   Mentions: 14     Fields:    Translation:Animals
    284. Left ventricular epicardial deformation in isolated arrested dog heart. Am J Physiol. 1987 Jan; 252(1 Pt 2):H233-41. McCulloch AD, Smaill BH, Hunter PJ. PMID: 3812713.
      View in: PubMed   Mentions: 13     Fields:    Translation:Animals
    285. Model of the kinetics of ketone bodies in humans. Am J Physiol. 1982 Jul; 243(1):R7-17. Cobelli C, Nosadini R, Toffolo G, McCulloch A, Avogaro A, Tiengo A, Alberti KG. PMID: 7091397.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    Andrew's Networks
    Concepts (777)
    Derived automatically from this person's publications.
    _
    Co-Authors (111)
    People in Profiles who have published with this person.
    _
    Similar People (60)
    People who share similar concepts with this person.
    _
    Same Department
    Search Department
    _