Adam Engler

Title(s)Professor, Bioengineering
SchoolVc-academic Affairs
Address9500 Gilman Drive #
La Jolla CA 92093
ORCID ORCID Icon0000-0003-1642-5380 Additional info
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    Collapse Research 
    Collapse Research Activities and Funding
    Biophysical Interrogation of Signals that Drive GBM Invasion
    NIH R01NS116802May 1, 2020 - Feb 28, 2025
    Role: Principal Investigator
    Mechanogenetics: An Integrated Approach in Muscle Dysfunction
    NIH/NIA 2R01AG045428Sep 30, 2018 - May 31, 2023
    Role: Principal Investigator
    Collaborative Research: Heterogeneous Cancer Cell Mechanics Differentially Drives Mechanosensing and Migration
    NSF 1763139Sep 15, 2018 - Aug 31, 2021
    Role: Principal Investigator
    Interprofessional Design and Entrepreneurship in Medical Devices at UC San Diego
    NIH R25EB023839Jun 5, 2018 - Mar 31, 2024
    Role: Principal Investigator
    Developing Adhesome Technology as a Physical Marker of Highly Metastatic Cells
    NIH R21CA217735May 1, 2018 - Apr 30, 2021
    Role: Principal Investigator
    Biomaterial Mimicry of Dynamic Matrix Stiffening During Tumor Progression
    NIH R01CA206880Jul 1, 2016 - Jun 30, 2021
    Role: Principal Investigator
    REU Site: Engineered Materials for Tissue Engineering and Drug Delivery
    NSF 1559781Apr 1, 2016 - Mar 30, 2019
    Role: Principal Investigator
    Strain-Activated Signaling within Cell Adhesions Dictates Cell Fate
    NSF 1463689Apr 1, 2015 - Mar 30, 2018
    Role: Principal Investigator
    Mechanogenetics: An Integrated Approach to Aging in Muscle Dysfunction
    NIH R01AG045428Aug 1, 2013 - May 31, 2023
    Role: Principal Investigator
    Stem Cells and Dynamic Materials Improve Cardiac Function Post-mycardial Infarcti
    NIH R21HL106529Jul 15, 2011 - Jun 30, 2013
    Role: Principal Investigator
    Improving Endoderm Specification with Hybrid Materials and Growth Factors
    NIH R21EB011727May 1, 2010 - Apr 30, 2013
    Role: Principal Investigator
    "Smart" Materials to Engineer a More Complete Stem Cell Niche
    NIH DP2OD006460Sep 30, 2009 - Jun 30, 2014
    Role: Principal Investigator

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    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Dispase/collagenase cocktail allows for coisolation of satellite cells and fibroadipogenic progenitors from human skeletal muscle. Am J Physiol Cell Physiol. 2024 Apr 01; 326(4):C1193-C1202. Balayan A, DeBoutray M, Molley TG, Ruoss S, Maceda M, Sevier A, Robertson CM, Ward SR, Engler AJ. PMID: 38581669.
      View in: PubMed   Mentions:
    2. AP-1 signaling modulates cardiac fibroblast stress responses. J Cell Sci. 2023 12 01; 136(23). Whitehead AJ, Atcha H, Hocker JD, Ren B, Engler AJ. PMID: 37994565; PMCID: PMC10753496.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    3. Conductive electrospun polymer improves stem cell-derived cardiomyocyte function and maturation. Biomaterials. 2023 11; 302:122363. Gonzalez G, Nelson AC, Holman AR, Whitehead AJ, LaMontagne E, Lian R, Vatsyayan R, Dayeh SA, Engler AJ. PMID: 37898021; PMCID: PMC10841997.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    4. YAP silencing by RB1 mutation is essential for small-cell lung cancer metastasis. Nat Commun. 2023 09 22; 14(1):5916. Wu Z, Su J, Li FL, Chen T, Mayner J, Engler A, Ma S, Li Q, Guan KL. PMID: 37739954; PMCID: PMC10516997.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    5. Using biophysical cues and biomaterials to improve genetic models. Curr Opin Biomed Eng. 2023 Dec; 28. Molley TG, Engler AJ. PMID: 37927406; PMCID: PMC10624401.
      View in: PubMed   Mentions:
    6. Mitochondrial MICOS complex genes, implicated in hypoplastic left heart syndrome, maintain cardiac contractility and actomyosin integrity. Elife. 2023 07 05; 12. Birker K, Ge S, Kirkland NJ, Theis JL, Marchant J, Fogarty ZC, Missinato MA, Kalvakuri S, Grossfeld P, Engler AJ, Ocorr K, Nelson TJ, Colas AR, Olson TM, Vogler G, Bodmer R. PMID: 37404133; PMCID: PMC10361721.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    7. Cell contractility drives mechanical memory of oral squamous cell carcinoma. Mol Biol Cell. 2023 08 01; 34(9):ar89. Moon SY, de Campos PS, Matte BF, Placone JK, Zanella VLG, Martins MD, Lamers ML, Engler AJ. PMID: 37342880; PMCID: PMC10398896.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    8. Heterogeneous expression of alternatively spliced lncRNA mediates vascular smooth cell plasticity. Proc Natl Acad Sci U S A. 2023 06 13; 120(24):e2217122120. Mayner JM, Masutani EM, Demeester E, Kumar A, Macapugay G, Beri P, Lo Sardo V, Engler AJ. PMID: 37276403; PMCID: PMC10268236.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    9. Getting physical: Material mechanics is an intrinsic cell cue. Cell Stem Cell. 2023 06 01; 30(6):750-765. Atcha H, Choi YS, Chaudhuri O, Engler AJ. PMID: 37267912; PMCID: PMC10247187.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    10. Age-dependent Lamin changes induce cardiac dysfunction via dysregulation of cardiac transcriptional programs. Nat Aging. 2023 01; 3(1):17-33. Kirkland NJ, Skalak SH, Whitehead AJ, Hocker JD, Beri P, Vogler G, Hum B, Wang M, Lakatta EG, Ren B, Bodmer R, Engler AJ. PMID: 36845078; PMCID: PMC9956937.
      View in: PubMed   Mentions: 5  Translation:AnimalsCells
    11. Mechanobiology of the cell nucleus. APL Bioeng. 2022 Dec; 6(4):040401. Lammerding J, Engler AJ, Kamm R. PMID: 36536804; PMCID: PMC9759352.
      View in: PubMed   Mentions: 2  
    12. Recent advancements and future requirements in vascularization of cortical organoids. Front Bioeng Biotechnol. 2022; 10:1048731. LaMontagne E, Muotri AR, Engler AJ. PMID: 36406234; PMCID: PMC9669755.
      View in: PubMed   Mentions: 5  
    13. Spatial transcriptomics tools allow for regional exploration of heterogeneous muscle pathology in the pre-clinical rabbit model of rotator cuff tear. J Orthop Surg Res. 2022 Oct 04; 17(1):440. Ruoss S, Esparza MC, Vasquez-Bolanos LS, Nasamran CA, Fisch KM, Engler AJ, Ward SR. PMID: 36195913; PMCID: PMC9531386.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    14. The Hippo pathway mediates Semaphorin signaling. Sci Adv. 2022 May 27; 8(21):eabl9806. Meng Z, Li FL, Fang C, Yeoman B, Qiu Y, Wang Y, Cai X, Lin KC, Yang D, Luo M, Fu V, Ma X, Diao Y, Giancotti FG, Ren B, Engler AJ, Guan KL. PMID: 35613278; PMCID: PMC9132450.
      View in: PubMed   Mentions: 3     Fields:    
    15. Subcellular Remodeling in Filamin C Deficient Mouse Hearts Impairs Myocyte Tension Development during Progression of Dilated Cardiomyopathy. Int J Mol Sci. 2022 Jan 14; 23(2). Powers JD, Kirkland NJ, Liu C, Razu SS, Fang X, Engler AJ, Chen J, McCulloch AD. PMID: 35055055; PMCID: PMC8779483.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    16. Engineering the niche to differentiate and deploy cardiovascular cells. Curr Opin Biotechnol. 2022 04; 74:122-128. Gonzalez G, Holman AR, Nelson AC, Engler AJ. PMID: 34861477; PMCID: PMC9064957.
      View in: PubMed   Mentions:    Fields:    
    17. Improved epicardial cardiac fibroblast generation from iPSCs. J Mol Cell Cardiol. 2022 03; 164:58-68. Whitehead AJ, Hocker JD, Ren B, Engler AJ. PMID: 34826415; PMCID: PMC9048147.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    18. Acetabular Bone Marrow Aspiration During Total Hip Arthroplasty. J Am Acad Orthop Surg. 2021 Aug 15; 29(16):e815-e819. Ruoss S, Ball ST, Dorn SN, Parekh JN, Whitehead AJ, Engler AJ, Ward SR. PMID: 34106093.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    19. High shear stress enhances endothelial permeability in the presence of the risk haplotype at 9p21.3. APL Bioeng. 2021 Sep; 5(3):036102. Teng EL, Masutani EM, Yeoman B, Fung J, Lian R, Ngo B, Kumar A, Placone JK, Lo Sardo V, Engler AJ. PMID: 34327295; PMCID: PMC8315817.
      View in: PubMed   Mentions: 2  
    20. Editorial: Understanding molecular interactions that underpin vascular mechanobiology. APL Bioeng. 2021 Sep; 5(3):030401. Engler AJ, Wang Y. PMID: 34258496; PMCID: PMC8253597.
      View in: PubMed   Mentions: 3  
    21. Regenerative cross talk between cardiac cells and macrophages. Am J Physiol Heart Circ Physiol. 2021 06 01; 320(6):H2211-H2221. Whitehead AJ, Engler AJ. PMID: 33769920; PMCID: PMC8289360.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    22. Adhesion strength and contractility enable metastatic cells to become adurotactic. Cell Rep. 2021 03 09; 34(10):108816. Yeoman B, Shatkin G, Beri P, Banisadr A, Katira P, Engler AJ. PMID: 33691109; PMCID: PMC7997775.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    23. Atomic Force Microscopy for Live-Cell and Hydrogel Measurement. Methods Mol Biol. 2021; 2299:217-226. Whitehead AJ, Kirkland NJ, Engler AJ. PMID: 34028746; PMCID: PMC9074798.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    24. EGFRvIII uses intrinsic and extrinsic mechanisms to reduce glioma adhesion and increase migration. J Cell Sci. 2020 12 24; 133(24). Banisadr A, Eick M, Beri P, Parisian AD, Yeoman B, Placone JK, Engler AJ, Furnari F. PMID: 33243756; PMCID: PMC7774888.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    25. Computational models of migration modes improve our understanding of metastasis. APL Bioeng. 2020 Dec; 4(4):041505. Shatkin G, Yeoman B, Birmingham K, Katira P, Engler AJ. PMID: 33195959; PMCID: PMC7647620.
      View in: PubMed   Mentions: 4  
    26. Matrix Rigidity Controls Epithelial-Mesenchymal Plasticity and Tumor Metastasis via a Mechanoresponsive EPHA2/LYN Complex. Dev Cell. 2020 08 10; 54(3):302-316.e7. Fattet L, Jung HY, Matsumoto MW, Aubol BE, Kumar A, Adams JA, Chen AC, Sah RL, Engler AJ, Pasquale EB, Yang J. PMID: 32574556; PMCID: PMC7423770.
      View in: PubMed   Mentions: 80     Fields:    Translation:HumansAnimalsCells
    27. Metabolic Dysregulation of the Lysophospholipid/Autotaxin Axis in the Chromosome 9p21 Gene SNP rs10757274. Circ Genom Precis Med. 2020 06; 13(3):e002806. Meckelmann SW, Hawksworth JI, White D, Andrews R, Rodrigues P, O'Connor A, Alvarez-Jarreta J, Tyrrell VJ, Hinz C, Zhou Y, Williams J, Aldrovandi M, Watkins WJ, Engler AJ, Lo Sardo V, Slatter DA, Allen SM, Acharya J, Mitchell J, Cooper J, Aoki J, Kano K, Humphries SE, O'Donnell VB. PMID: 32396387; PMCID: PMC7299226.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    28. Academic vs industry perspectives in 3D bioprinting. APL Bioeng. 2020 Mar; 4(1):010401. Engler AJ, Cooper-White J. PMID: 32161831; PMCID: PMC7054121.
      View in: PubMed   Mentions: 5  
    29. Multi-scale cellular engineering: From molecules to organ-on-a-chip. APL Bioeng. 2020 Mar; 4(1):010906. Huang NF, Chaudhuri O, Cahan P, Wang A, Engler AJ, Wang Y, Kumar S, Khademhosseini A, Li S. PMID: 32161833; PMCID: PMC7054123.
      View in: PubMed   Mentions: 5  
    30. H-Ras Transformation of Mammary Epithelial Cells Induces ERK-Mediated Spreading on Low Stiffness Matrix. Adv Healthc Mater. 2020 04; 9(8):e1901366. Plunkett C, Kumar A, Yrastorza J, Hou YH, Placone JK, Grennan G, Engler AJ. PMID: 31951109; PMCID: PMC7274860.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    31. Cell Adhesiveness Serves as a Biophysical Marker for Metastatic Potential. Cancer Res. 2020 02 15; 80(4):901-911. Beri P, Popravko A, Yeoman B, Kumar A, Chen K, Hodzic E, Chiang A, Banisadr A, Placone JK, Carter H, Fraley SI, Katira P, Engler AJ. PMID: 31857292; PMCID: PMC7024658.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    32. Substrate stiffness directs diverging vascular fates. Acta Biomater. 2019 09 15; 96:321-329. Wong L, Kumar A, Gabela-Zuniga B, Chua J, Singh G, Happe CL, Engler AJ, Fan Y, McCloskey KE. PMID: 31326665.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    33. 3D collagen architecture regulates cell adhesion through degradability, thereby controlling metabolic and oxidative stress. Integr Biol (Camb). 2019 05 01; 11(5):221-234. Velez DO, Ranamukhaarachchi SK, Kumar A, Modi RN, Lim EW, Engler AJ, Metallo CM, Fraley SI. PMID: 31251330; PMCID: PMC6657753.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    34. Mechanical influences on cardiovascular differentiation and disease modeling. Exp Cell Res. 2019 04 15; 377(1-2):103-108. Teng EL, Engler AJ. PMID: 30794804; PMCID: PMC6408970.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    35. Dynamically stiffened matrix promotes malignant transformation of mammary epithelial cells via collective mechanical signaling. Proc Natl Acad Sci U S A. 2019 02 26; 116(9):3502-3507. Ondeck MG, Kumar A, Placone JK, Plunkett CM, Matte BF, Wong KC, Fattet L, Yang J, Engler AJ. PMID: 30755531; PMCID: PMC6397509.
      View in: PubMed   Mentions: 58     Fields:    Translation:HumansCells
    36. Combinatorial interactions of genetic variants in human cardiomyopathy. Nat Biomed Eng. 2019 02; 3(2):147-157. Deacon DC, Happe CL, Chen C, Tedeschi N, Manso AM, Li T, Dalton ND, Peng Q, Farah EN, Gu Y, Tenerelli KP, Tran VD, Chen J, Peterson KL, Schork NJ, Adler ED, Engler AJ, Ross RS, Chi NC. PMID: 30923642; PMCID: PMC6433174.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    37. Macromolecular crowding tunes 3D collagen architecture and cell morphogenesis. Biomater Sci. 2019 Jan 29; 7(2):618-633. Ranamukhaarachchi SK, Modi RN, Han A, Velez DO, Kumar A, Engler AJ, Fraley SI. PMID: 30515503; PMCID: PMC6375559.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    38. Mechanical activation of noncoding-RNA-mediated regulation of disease-associated phenotypes in human cardiomyocytes. Nat Biomed Eng. 2019 Feb; 3(2):137-146. Kumar A, Thomas SK, Wong KC, Lo Sardo V, Cheah DS, Hou YH, Placone JK, Tenerelli KP, Ferguson WC, Torkamani A, Topol EJ, Baldwin KK, Engler AJ. PMID: 30911429; PMCID: PMC6430136.
      View in: PubMed   Mentions: 17     Fields:    
    39. Matrix stiffness mechanically conditions EMT and migratory behavior of oral squamous cell carcinoma. J Cell Sci. 2019 01 09; 132(1). Matte BF, Kumar A, Placone JK, Zanella VG, Martins MD, Engler AJ, Lamers ML. PMID: 30559248; PMCID: PMC6340137.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansCells
    40. Fifteen years of Servitude et Grandeur to the application of a biophysical technique in medicine: The tale of AFMBioMed. J Mol Recognit. 2019 03; 32(3):e2773. Pellequer JL, Parot P, Navajas D, Kumar S, Svetlicic V, Scheuring S, Hu J, Li B, Engler A, Sousa S, Lekka M, Szymonski M, Schillers H, Odorico M, Lafont F, Janel S, Rico F. PMID: 30565321.
      View in: PubMed   Mentions:    Fields:    
    41. Unveiling the Role of the Most Impactful Cardiovascular Risk Locus through Haplotype Editing. Cell. 2018 12 13; 175(7):1796-1810.e20. Lo Sardo V, Chubukov P, Ferguson W, Kumar A, Teng EL, Duran M, Zhang L, Cost G, Engler AJ, Urnov F, Topol EJ, Torkamani A, Baldwin KK. PMID: 30528432; PMCID: PMC6346426.
      View in: PubMed   Mentions: 60     Fields:    Translation:HumansCells
    42. Rationally engineered advances in cancer research. APL Bioeng. 2018 Sep; 2(3):031601. Engler AJ, Discher DE. PMID: 31069310; PMCID: PMC6481711.
      View in: PubMed   Mentions:
    43. Biomaterials to model and measure epithelial cancers. Nat Rev Mater. 2018 Nov; 3(11):418-430. Beri P, Matte BF, Fattet L, Kim D, Yang J, Engler AJ. PMID: 30416759; PMCID: PMC6224155.
      View in: PubMed   Mentions: 14  
    44. RAP2 mediates mechanoresponses of the Hippo pathway. Nature. 2018 08; 560(7720):655-660. Meng Z, Qiu Y, Lin KC, Kumar A, Placone JK, Fang C, Wang KC, Lu S, Pan M, Hong AW, Moroishi T, Luo M, Plouffe SW, Diao Y, Ye Z, Park HW, Wang X, Yu FX, Chien S, Wang CY, Ren B, Engler AJ, Guan KL. PMID: 30135582; PMCID: PMC6128698.
      View in: PubMed   Mentions: 156     Fields:    Translation:HumansAnimalsCells
    45. Preserved cardiac function by vinculin enhances glucose oxidation and extends health- and life-span. APL Bioeng. 2018 Sep; 2(3). Sessions AO, Min P, Cordes T, Weickert BJ, Divakaruni AS, Murphy AN, Metallo CM, Engler AJ. PMID: 30105314; PMCID: PMC6086353.
      View in: PubMed   Mentions: 3  
    46. Extracellular matrix in lung development, homeostasis and disease. Matrix Biol. 2018 11; 73:77-104. Zhou Y, Horowitz JC, Naba A, Ambalavanan N, Atabai K, Balestrini J, Bitterman PB, Corley RA, Ding BS, Engler AJ, Hansen KC, Hagood JS, Kheradmand F, Lin QS, Neptune E, Niklason L, Ortiz LA, Parks WC, Tschumperlin DJ, White ES, Chapman HA, Thannickal VJ. PMID: 29524630; PMCID: PMC6129220.
      View in: PubMed   Mentions: 113     Fields:    Translation:HumansCells
    47. Heterogeneous muscle gene expression patterns in patients with massive rotator cuff tears. PLoS One. 2018; 13(1):e0190439. Gibbons MC, Fisch KM, Pichika R, Cheng T, Engler AJ, Schenk S, Lane JG, Singh A, Ward SR. PMID: 29293645; PMCID: PMC5749784.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    48. Recent Advances in Extrusion-Based 3D Printing for Biomedical Applications. Adv Healthc Mater. 2018 04; 7(8):e1701161. Placone JK, Engler AJ. PMID: 29283220; PMCID: PMC5954828.
      View in: PubMed   Mentions: 78     Fields:    Translation:HumansAnimals
    49. Understanding the extracellular forces that determine cell fate and maintenance. Development. 2017 12 01; 144(23):4261-4270. Kumar A, Placone JK, Engler AJ. PMID: 29183939; PMCID: PMC5769638.
      View in: PubMed   Mentions: 60     Fields:    Translation:HumansAnimalsCells
    50. The role of mechanobiology in progression of rotator cuff muscle atrophy and degeneration. J Orthop Res. 2018 02; 36(2):546-556. Gibbons MC, Singh A, Engler AJ, Ward SR. PMID: 28755470; PMCID: PMC5788743.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    51. The provisional matrix: setting the stage for tissue repair outcomes. Matrix Biol. 2017 07; 60-61:1-4. Barker TH, Engler AJ. PMID: 28527902; PMCID: PMC5831186.
      View in: PubMed   Mentions: 65     Fields:    Translation:HumansAnimalsCells
    52. Stem cell migration and mechanotransduction on linear stiffness gradient hydrogels. Proc Natl Acad Sci U S A. 2017 05 30; 114(22):5647-5652. Hadden WJ, Young JL, Holle AW, McFetridge ML, Kim DY, Wijesinghe P, Taylor-Weiner H, Wen JH, Lee AR, Bieback K, Vo BN, Sampson DD, Kennedy BF, Spatz JP, Engler AJ, Choi YS. PMID: 28507138; PMCID: PMC5465928.
      View in: PubMed   Mentions: 147     Fields:    Translation:HumansCells
    53. Mechanically patterned neuromuscular junctions-in-a-dish have improved functional maturation. Mol Biol Cell. 2017 Jul 07; 28(14):1950-1958. Happe CL, Tenerelli KP, Gromova AK, Kolb F, Engler AJ. PMID: 28495800; PMCID: PMC5541845.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    54. Mechanical regulation of cardiac fibroblast profibrotic phenotypes. Mol Biol Cell. 2017 Jul 07; 28(14):1871-1882. Herum KM, Choppe J, Kumar A, Engler AJ, McCulloch AD. PMID: 28468977; PMCID: PMC5541838.
      View in: PubMed   Mentions: 97     Fields:    Translation:AnimalsCells
    55. Metastatic State of Cancer Cells May Be Indicated by Adhesion Strength. Biophys J. 2017 Feb 28; 112(4):736-745. Fuhrmann A, Banisadr A, Beri P, Tlsty TD, Engler AJ. PMID: 28256233; PMCID: PMC5340156.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCells
    56. Modest overexpression of FOXO maintains cardiac proteostasis and ameliorates age-associated functional decline. Aging Cell. 2017 Feb; 16(1):93-103. Blice-Baum AC, Zambon AC, Kaushik G, Viswanathan MC, Engler AJ, Bodmer R, Cammarato A. PMID: 28090761; PMCID: PMC5242305.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    57. Histological Evidence of Muscle Degeneration in Advanced Human Rotator Cuff Disease. J Bone Joint Surg Am. 2017 Feb 01; 99(3):190-199. Gibbons MC, Singh A, Anakwenze O, Cheng T, Pomerantz M, Schenk S, Engler AJ, Ward SR. PMID: 28145949; PMCID: PMC5395080.
      View in: PubMed   Mentions: 43     Fields:    Translation:Humans
    58. Extracellular matrix downregulation in the Drosophila heart preserves contractile function and improves lifespan. Matrix Biol. 2017 10; 62:15-27. Sessions AO, Kaushik G, Parker S, Raedschelders K, Bodmer R, Van Eyk JE, Engler AJ. PMID: 27793636; PMCID: PMC5405015.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    59. Rotator cuff tear state modulates self-renewal and differentiation capacity of human skeletal muscle progenitor cells. J Orthop Res. 2017 08; 35(8):1816-1823. Thomas KA, Gibbons MC, Lane JG, Singh A, Ward SR, Engler AJ. PMID: 27699827; PMCID: PMC5438295.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    60. High content image analysis of focal adhesion-dependent mechanosensitive stem cell differentiation. Integr Biol (Camb). 2016 10 10; 8(10):1049-1058. Holle AW, McIntyre AJ, Kehe J, Wijesekara P, Young JL, Vincent LG, Engler AJ. PMID: 27723854; PMCID: PMC5079280.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    61. Sixth International AFM BioMed Conference on AFM in life sciences and medicine, December 13 to 17, 2014, San Diego, California. J Mol Recognit. 2016 09; 29(9):404-5. Engler AJ, Parot P, Pellequer JL. PMID: 27502838.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    62. Mechanical Regulation of Cardiac Aging in Model Systems. Circ Res. 2016 05 13; 118(10):1553-62. Sessions AO, Engler AJ. PMID: 27174949; PMCID: PMC4868502.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    63. Muscle architectural changes after massive human rotator cuff tear. J Orthop Res. 2016 12; 34(12):2089-2095. Gibbons MC, Sato EJ, Bachasson D, Cheng T, Azimi H, Schenk S, Engler AJ, Singh A, Ward SR. PMID: 27061583; PMCID: PMC5423410.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    64. Layered hydrogels accelerate iPSC-derived neuronal maturation and reveal migration defects caused by MeCP2 dysfunction. Proc Natl Acad Sci U S A. 2016 Mar 22; 113(12):3185-90. Zhang ZN, Freitas BC, Qian H, Lux J, Acab A, Trujillo CA, Herai RH, Nguyen Huu VA, Wen JH, Joshi-Barr S, Karpiak JV, Engler AJ, Fu XD, Muotri AR, Almutairi A. PMID: 26944080; PMCID: PMC4812712.
      View in: PubMed   Mentions: 66     Fields:    Translation:HumansCells
    65. Mechanical Characterization of a Dynamic and Tunable Methacrylated Hyaluronic Acid Hydrogel. J Biomech Eng. 2016 Feb; 138(2):021003. Ondeck MG, Engler AJ. PMID: 26746491; PMCID: PMC4844086.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    66. Mechanical Forces Reshape Differentiation Cues That Guide Cardiomyogenesis. Circ Res. 2016 Jan 22; 118(2):296-310. Happe CL, Engler AJ. PMID: 26838315; PMCID: PMC4743530.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimalsCells
    67. The cytoskeleton regulates cell attachment strength. Biophys J. 2015 Jul 07; 109(1):57-65. Fuhrmann A, Engler AJ. PMID: 26153702; PMCID: PMC4572469.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    68. Epigenetic Regulation of Phosphodiesterases 2A and 3A Underlies Compromised β-Adrenergic Signaling in an iPSC Model of Dilated Cardiomyopathy. Cell Stem Cell. 2015 Jul 02; 17(1):89-100. Wu H, Lee J, Vincent LG, Wang Q, Gu M, Lan F, Churko JM, Sallam KI, Matsa E, Sharma A, Gold JD, Engler AJ, Xiang YK, Bers DM, Wu JC. PMID: 26095046; PMCID: PMC4546705.
      View in: PubMed   Mentions: 106     Fields:    Translation:HumansCells
    69. Vinculin network-mediated cytoskeletal remodeling regulates contractile function in the aging heart. Sci Transl Med. 2015 Jun 17; 7(292):292ra99. Kaushik G, Spenlehauer A, Sessions AO, Trujillo AS, Fuhrmann A, Fu Z, Venkatraman V, Pohl D, Tuler J, Wang M, Lakatta EG, Ocorr K, Bodmer R, Bernstein SI, Van Eyk JE, Cammarato A, Engler AJ. PMID: 26084806; PMCID: PMC4507505.
      View in: PubMed   Mentions: 56     Fields:    Translation:HumansAnimalsCells
    70. Haptotaxis is cell type specific and limited by substrate adhesiveness. Cell Mol Bioeng. 2015 Dec 01; 8(4):530-542. Wen JH, Choi O, Taylor-Weiner H, Fuhrmann A, Karpiak JV, Almutairi A, Engler AJ. PMID: 26640598; PMCID: PMC4667988.
      View in: PubMed   Mentions: 13  
    71. Epimuscular Fat in the Human Rotator Cuff Is a Novel Beige Depot. Stem Cells Transl Med. 2015 Jul; 4(7):764-74. Meyer GA, Gibbons MC, Sato E, Lane JG, Ward SR, Engler AJ. PMID: 25999520; PMCID: PMC4479624.
      View in: PubMed   Mentions: 16     Fields:    
    72. Traction forces mediated by integrin signaling are necessary for definitive endoderm specification. J Cell Sci. 2015 May 15; 128(10):1961-8. Taylor-Weiner H, Ravi N, Engler AJ. PMID: 25908864; PMCID: PMC4457159.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    73. Nonlinear 3D projection printing of concave hydrogel microstructures for long-term multicellular spheroid and embryoid body culture. Lab Chip. 2015 Jun 07; 15(11):2412-8. Hribar KC, Finlay D, Ma X, Qu X, Ondeck MG, Chung PH, Zanella F, Engler AJ, Sheikh F, Vuori K, Chen SC. PMID: 25900329; PMCID: PMC4439309.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansCells
    74. Matrix stiffness drives epithelial-mesenchymal transition and tumour metastasis through a TWIST1-G3BP2 mechanotransduction pathway. Nat Cell Biol. 2015 May; 17(5):678-88. Wei SC, Fattet L, Tsai JH, Guo Y, Pai VH, Majeski HE, Chen AC, Sah RL, Taylor SS, Engler AJ, Yang J. PMID: 25893917; PMCID: PMC4452027.
      View in: PubMed   Mentions: 407     Fields:    Translation:HumansAnimalsCells
    75. Transfer stamping of human mesenchymal stem cell patches using thermally expandable hydrogels with tunable cell-adhesive properties. Biomaterials. 2015 Jun; 54:44-54. Jun I, Lee YB, Choi YS, Engler AJ, Park H, Shin H. PMID: 25907038.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    76. 3D surface topology guides stem cell adhesion and differentiation. Biomaterials. 2015 Jun; 52:140-7. Viswanathan P, Ondeck MG, Chirasatitsin S, Ngamkham K, Reilly GC, Engler AJ, Battaglia G. PMID: 25818420; PMCID: PMC4379418.
      View in: PubMed   Mentions: 56     Fields:    Translation:HumansCells
    77. Acute shear stress direction dictates adherent cell remodeling and verifies shear profile of spinning disk assays. Phys Biol. 2015 Jan 26; 12(1):016011. Fuhrmann A, Engler AJ. PMID: 25619322; PMCID: PMC4323404.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    78. Muscle progenitor cell regenerative capacity in the torn rotator cuff. J Orthop Res. 2015 Mar; 33(3):421-9. Meyer GA, Farris AL, Sato E, Gibbons M, Lane JG, Ward SR, Engler AJ. PMID: 25410765; PMCID: PMC4346515.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    79. Mechanosensitive kinases regulate stiffness-induced cardiomyocyte maturation. Sci Rep. 2014 Sep 19; 4:6425. Young JL, Kretchmer K, Ondeck MG, Zambon AC, Engler AJ. PMID: 25236849; PMCID: PMC4168277.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    80. Digital Plasmonic Patterning for Localized Tuning of Hydrogel Stiffness. Adv Funct Mater. 2014 Aug 20; 24(31):4922-4926. Hribar KC, Choi YS, Ondeck M, Engler AJ, Chen S. PMID: 26120293; PMCID: PMC4479157.
      View in: PubMed   Mentions: 18  
    81. Extracellular matrix regulation in the muscle satellite cell niche. Connect Tissue Res. 2015 Feb; 56(1):1-8. Thomas K, Engler AJ, Meyer GA. PMID: 25047058; PMCID: PMC4464813.
      View in: PubMed   Mentions: 81     Fields:    Translation:HumansAnimalsCells
    82. Interplay of matrix stiffness and protein tethering in stem cell differentiation. Nat Mater. 2014 Oct; 13(10):979-87. Wen JH, Vincent LG, Fuhrmann A, Choi YS, Hribar KC, Taylor-Weiner H, Chen S, Engler AJ. PMID: 25108614; PMCID: PMC4172528.
      View in: PubMed   Mentions: 334     Fields:    Translation:HumansCells
    83. Cation type specific cell remodeling regulates attachment strength. PLoS One. 2014; 9(7):e102424. Fuhrmann A, Li J, Chien S, Engler AJ. PMID: 25014042; PMCID: PMC4094514.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    84. Materials as stem cell regulators. Nat Mater. 2014 Jun; 13(6):547-57. Murphy WL, McDevitt TC, Engler AJ. PMID: 24845994; PMCID: PMC4163547.
      View in: PubMed   Mentions: 276     Fields:    Translation:HumansAnimalsCells
    85. A dual role for integrin-linked kinase and β1-integrin in modulating cardiac aging. Aging Cell. 2014 Jun; 13(3):431-40. Nishimura M, Kumsta C, Kaushik G, Diop SB, Ding Y, Bisharat-Kernizan J, Catan H, Cammarato A, Ross RS, Engler AJ, Bodmer R, Hansen M, Ocorr K. PMID: 24400780; PMCID: PMC4032615.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimalsCells
    86. From stem cells to cardiomyocytes: the role of forces in cardiac maturation, aging, and disease. Prog Mol Biol Transl Sci. 2014; 126:219-42. Kaushik G, Engler AJ. PMID: 25081620; PMCID: PMC6281561.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    87. Mechanotransduction. Preface. Prog Mol Biol Transl Sci. 2014; 126:xiii-xiv. Engler AJ, Kumar S. PMID: 25081625.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    88. A Drosophila melanogaster model of diastolic dysfunction and cardiomyopathy based on impaired troponin-T function. Circ Res. 2014 Jan 17; 114(2):e6-17. Viswanathan MC, Kaushik G, Engler AJ, Lehman W, Cammarato A. PMID: 24221941; PMCID: PMC4526186.
      View in: PubMed   Mentions: 31     Fields:    Translation:AnimalsCells
    89. In situ mechanotransduction via vinculin regulates stem cell differentiation. Stem Cells. 2013 Nov; 31(11):2467-77. Holle AW, Tang X, Vijayraghavan D, Vincent LG, Fuhrmann A, Choi YS, del Álamo JC, Engler AJ. PMID: 23897765; PMCID: PMC3833960.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansCells
    90. Defined extracellular matrix components are necessary for definitive endoderm induction. Stem Cells. 2013 Oct; 31(10):2084-94. Taylor-Weiner H, Schwarzbauer JE, Engler AJ. PMID: 23766144; PMCID: PMC3812380.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    91. A co-culture device with a tunable stiffness to understand combinatorial cell-cell and cell-matrix interactions. Integr Biol (Camb). 2013 Nov; 5(11):1344-54. Rao N, Grover GN, Vincent LG, Evans SC, Choi YS, Spencer KH, Hui EE, Engler AJ, Christman KL. PMID: 24061208; PMCID: PMC3848881.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    92. Stimulation of adipogenesis of adult adipose-derived stem cells using substrates that mimic the stiffness of adipose tissue. Biomaterials. 2013 Nov; 34(34):8581-8. Young DA, Choi YS, Engler AJ, Christman KL. PMID: 23953825; PMCID: PMC3786695.
      View in: PubMed   Mentions: 92     Fields:    Translation:HumansCells
    93. Stem cell differentiation: Post-degradation forces kick in. Nat Mater. 2013 May; 12(5):384-6. Vincent LG, Engler AJ. PMID: 23603879.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    94. In vivo response to dynamic hyaluronic acid hydrogels. Acta Biomater. 2013 Jul; 9(7):7151-7. Young JL, Tuler J, Braden R, Schüp-Magoffin P, Schaefer J, Kretchmer K, Christman KL, Engler AJ. PMID: 23523533; PMCID: PMC3674107.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    95. Mesenchymal stem cell durotaxis depends on substrate stiffness gradient strength. Biotechnol J. 2013 Apr; 8(4):472-84. Vincent LG, Choi YS, Alonso-Latorre B, del Álamo JC, Engler AJ. PMID: 23390141; PMCID: PMC3749305.
      View in: PubMed   Mentions: 85     Fields:    Translation:HumansCells
    96. Density gradient multilayered polymerization (DGMP): a novel technique for creating multi-compartment, customizable scaffolds for tissue engineering. J Vis Exp. 2013 Feb 12; (72). Joshi-Barr S, Karpiak JV, Ner Y, Wen JH, Engler AJ, Almutairi A. PMID: 23426045; PMCID: PMC3601043.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    97. Dynamic and reversible surface topography influences cell morphology. J Biomed Mater Res A. 2013 Aug; 101(8):2313-21. Kiang JD, Wen JH, del Álamo JC, Engler AJ. PMID: 23355509; PMCID: PMC4433743.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    98. Cell instructive microporous scaffolds through interface engineering. J Am Chem Soc. 2012 Dec 12; 134(49):20103-9. Viswanathan P, Chirasatitsin S, Ngamkham K, Engler AJ, Battaglia G. PMID: 23163574; PMCID: PMC3556732.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    99. Control of stem cell fate and function by engineering physical microenvironments. Integr Biol (Camb). 2012 Sep; 4(9):1008-18. Park J, Kim P, Helen W, Engler AJ, Levchenko A, Kim DH. PMID: 23077731; PMCID: PMC3476065.
      View in: PubMed   Mentions: 84     Fields:    
    100. Measuring passive myocardial stiffness in Drosophila melanogaster to investigate diastolic dysfunction. J Cell Mol Med. 2012 Aug; 16(8):1656-62. Kaushik G, Zambon AC, Fuhrmann A, Bernstein SI, Bodmer R, Engler AJ, Cammarato A. PMID: 22225769; PMCID: PMC3326184.
      View in: PubMed   Mentions: 22     Fields:    Translation:Animals
    101. The alignment and fusion assembly of adipose-derived stem cells on mechanically patterned matrices. Biomaterials. 2012 Oct; 33(29):6943-51. Choi YS, Vincent LG, Lee AR, Kretchmer KC, Chirasatitsin S, Dobke MK, Engler AJ. PMID: 22800539; PMCID: PMC3408879.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansAnimalsCells
    102. Mechanical derivation of functional myotubes from adipose-derived stem cells. Biomaterials. 2012 Mar; 33(8):2482-91. Choi YS, Vincent LG, Lee AR, Dobke MK, Engler AJ. PMID: 22197570; PMCID: PMC3261363.
      View in: PubMed   Mentions: 51     Fields:    Translation:HumansCells
    103. In situ mechanical analysis of myofibrillar perturbation and aging on soft, bilayered Drosophila myocardium. Biophys J. 2011 Dec 07; 101(11):2629-37. Kaushik G, Fuhrmann A, Cammarato A, Engler AJ. PMID: 22261050; PMCID: PMC3297788.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    104. Wet nanoscale imaging and testing of polymersomes. Small. 2011 Jul 18; 7(14):2010-5. Battaglia G, LoPresti C, Massignani M, Warren NJ, Madsen J, Forster S, Vasilev C, Hobbs JK, Armes SP, Chirasatitsin S, Engler AJ. PMID: 21695783; PMCID: PMC3325755.
      View in: PubMed   Mentions: 7     Fields:    Translation:Cells
    105. More than a feeling: discovering, understanding, and influencing mechanosensing pathways. Curr Opin Biotechnol. 2011 Oct; 22(5):648-54. Holle AW, Engler AJ. PMID: 21536426; PMCID: PMC3150613.
      View in: PubMed   Mentions: 57     Fields:    Translation:Cells
    106. Controlling polymersome surface topology at the nanoscale by membrane confined polymer/polymer phase separation. ACS Nano. 2011 Mar 22; 5(3):1775-84. LoPresti C, Massignani M, Fernyhough C, Blanazs A, Ryan AJ, Madsen J, Warren NJ, Armes SP, Lewis AL, Chirasatitsin S, Engler AJ, Battaglia G. PMID: 21344879.
      View in: PubMed   Mentions: 30     Fields:    Translation:Cells
    107. Stiffness gradients mimicking in vivo tissue variation regulate mesenchymal stem cell fate. PLoS One. 2011 Jan 05; 6(1):e15978. Tse JR, Engler AJ. PMID: 21246050; PMCID: PMC3016411.
      View in: PubMed   Mentions: 158     Fields:    Translation:HumansCells
    108. Hydrogels with time-dependent material properties enhance cardiomyocyte differentiation in vitro. Biomaterials. 2011 Feb; 32(4):1002-9. Young JL, Engler AJ. PMID: 21071078; PMCID: PMC3000555.
      View in: PubMed   Mentions: 144     Fields:    Translation:AnimalsCells
    109. Preparation of hydrogel substrates with tunable mechanical properties. Curr Protoc Cell Biol. 2010 Jun; Chapter 10:Unit 10.16. Tse JR, Engler AJ. PMID: 20521229.
      View in: PubMed   Mentions: 391     Fields:    Translation:HumansAnimalsCells
    110. Detecting cell-adhesive sites in extracellular matrix using force spectroscopy mapping. J Phys Condens Matter. 2010 May 19; 22(19):194102. Chirasatitsin S, Engler AJ. PMID: 21152375; PMCID: PMC2997741.
      View in: PubMed   Mentions: 10     Fields:    Translation:Cells
    111. Nanoscopic mechanical anisotropy in hydrogel surfaces. Soft Matter. 2010 Jan 01; 6(18):4466-4470. Flores-Merino MV, Chirasatitsin S, Lopresti C, Reilly GC, Battaglia G, Engler AJ. PMID: 20953281; PMCID: PMC2954611.
      View in: PubMed   Mentions: 12     Fields:    
    112. Cell rheology: Stressed-out stem cells. Nat Mater. 2010 Jan; 9(1):4-6. Holle AW, Engler AJ. PMID: 20019660.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    113. Innovations in cell mechanobiology. J Biomech. 2010 Jan 05; 43(1):1. David Merryman W, Engler AJ. PMID: 19815212.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    114. Intrinsic extracellular matrix properties regulate stem cell differentiation. J Biomech. 2010 Jan 05; 43(1):55-62. Reilly GC, Engler AJ. PMID: 19800626.
      View in: PubMed   Mentions: 221     Fields:    Translation:HumansAnimalsCells
    115. A novel mode of cell detachment from fibrillar fibronectin matrix under shear. J Cell Sci. 2009 May 15; 122(Pt 10):1647-53. Engler AJ, Chan M, Boettiger D, Schwarzbauer JE. PMID: 19401337; PMCID: PMC2680103.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    116. Multiscale modeling of form and function. Science. 2009 Apr 10; 324(5924):208-12. Engler AJ, Humbert PO, Wehrle-Haller B, Weaver VM. PMID: 19359578; PMCID: PMC4527531.
      View in: PubMed   Mentions: 59     Fields:    Translation:AnimalsCells
    117. Matrix strains induced by cells: Computing how far cells can feel. Cell Mol Bioeng. 2009 Mar 01; 2(1):39-48. Sen S, Engler AJ, Discher DE. PMID: 20582230; PMCID: PMC2891090.
      View in: PubMed   Mentions: 57  
    118. Stem cell fate dictated solely by altered nanotube dimension. Proc Natl Acad Sci U S A. 2009 Feb 17; 106(7):2130-5. Oh S, Brammer KS, Li YS, Teng D, Engler AJ, Chien S, Jin S. PMID: 19179282; PMCID: PMC2650120.
      View in: PubMed   Mentions: 270     Fields:    Translation:HumansCells
    119. Embryonic cardiomyocytes beat best on a matrix with heart-like elasticity: scar-like rigidity inhibits beating. J Cell Sci. 2008 Nov 15; 121(Pt 22):3794-802. Engler AJ, Carag-Krieger C, Johnson CP, Raab M, Tang HY, Speicher DW, Sanger JW, Sanger JM, Discher DE. PMID: 18957515; PMCID: PMC2740334.
      View in: PubMed   Mentions: 365     Fields:    Translation:AnimalsCells
    120. Fibronectin expression modulates mammary epithelial cell proliferation during acinar differentiation. Cancer Res. 2008 May 01; 68(9):3185-92. Williams CM, Engler AJ, Slone RD, Galante LL, Schwarzbauer JE. PMID: 18451144; PMCID: PMC2748963.
      View in: PubMed   Mentions: 99     Fields:    Translation:HumansCells
    121. Extracellular matrix elasticity directs stem cell differentiation. J Musculoskelet Neuronal Interact. 2007 Oct-Dec; 7(4):335. Engler AJ, Sweeney HL, Discher DE, Schwarzbauer JE. PMID: 18094500.
      View in: PubMed   Mentions: 68     Fields:    Translation:HumansAnimalsCells
    122. Cell responses to the mechanochemical microenvironment--implications for regenerative medicine and drug delivery. Adv Drug Deliv Rev. 2007 Nov 10; 59(13):1329-39. Rehfeldt F, Engler AJ, Eckhardt A, Ahmed F, Discher DE. PMID: 17900747; PMCID: PMC4124491.
      View in: PubMed   Mentions: 98     Fields:    Translation:HumansAnimals
    123. Microscopic methods for measuring the elasticity of gel substrates for cell culture: microspheres, microindenters, and atomic force microscopy. Methods Cell Biol. 2007; 83:47-65. Frey MT, Engler A, Discher DE, Lee J, Wang YL. PMID: 17613304.
      View in: PubMed   Mentions: 28     Fields:    
    124. Microtissue elasticity: measurements by atomic force microscopy and its influence on cell differentiation. Methods Cell Biol. 2007; 83:521-45. Engler AJ, Rehfeldt F, Sen S, Discher DE. PMID: 17613323.
      View in: PubMed   Mentions: 76     Fields:    Translation:AnimalsCells
    125. Matrix elasticity directs stem cell lineage specification. Cell. 2006 Aug 25; 126(4):677-89. Engler AJ, Sen S, Sweeney HL, Discher DE. PMID: 16923388.
      View in: PubMed   Mentions: 4532     Fields:    Translation:HumansCells
    126. A hemoglobin fragment found in cervicovaginal fluid from women in labor potentiates the action of agents that promote contraction of smooth muscle cells. Peptides. 2006 Jul; 27(7):1794-800. Brown AG, Leite RS, Engler AJ, Discher DE, Strauss JF. PMID: 16621150.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    127. Mesenchymal stem cell injection after myocardial infarction improves myocardial compliance. Am J Physiol Heart Circ Physiol. 2006 Jun; 290(6):H2196-203. Berry MF, Engler AJ, Woo YJ, Pirolli TJ, Bish LT, Jayasankar V, Morine KJ, Gardner TJ, Discher DE, Sweeney HL. PMID: 16473959.
      View in: PubMed   Mentions: 292     Fields:    Translation:AnimalsCells
    128. Power-law rheology of isolated nuclei with deformation mapping of nuclear substructures. Biophys J. 2005 Oct; 89(4):2855-64. Dahl KN, Engler AJ, Pajerowski JD, Discher DE. PMID: 16055543; PMCID: PMC1366783.
      View in: PubMed   Mentions: 153     Fields:    Translation:AnimalsCells
    129. Myotubes differentiate optimally on substrates with tissue-like stiffness: pathological implications for soft or stiff microenvironments. J Cell Biol. 2004 Sep 13; 166(6):877-87. Engler AJ, Griffin MA, Sen S, Bönnemann CG, Sweeney HL, Discher DE. PMID: 15364962; PMCID: PMC2172122.
      View in: PubMed   Mentions: 567     Fields:    Translation:AnimalsCells
    130. Targeted worm micelles. Biomacromolecules. 2004 Sep-Oct; 5(5):1714-9. Dalhaimer P, Engler AJ, Parthasarathy R, Discher DE. PMID: 15360279.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    131. Elasticity of native and cross-linked polyelectrolyte multilayer films. Biomacromolecules. 2004 Sep-Oct; 5(5):1908-16. Richert L, Engler AJ, Discher DE, Picart C. PMID: 15360305.
      View in: PubMed   Mentions: 42     Fields:    
    132. Patterning, prestress, and peeling dynamics of myocytes. Biophys J. 2004 Feb; 86(2):1209-22. Griffin MA, Engler AJ, Barber TA, Healy KE, Sweeney HL, Discher DE. PMID: 14747355; PMCID: PMC1303913.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    133. Substrate compliance versus ligand density in cell on gel responses. Biophys J. 2004 Jan; 86(1 Pt 1):617-28. Engler A, Bacakova L, Newman C, Hategan A, Griffin M, Discher D. PMID: 14695306; PMCID: PMC1303831.
      View in: PubMed   Mentions: 392     Fields:    Translation:AnimalsCells
    134. Solution structure of human immunodeficiency virus type 1 Vpr(13-33) peptide in micelles. Eur J Biochem. 2001 Jan; 268(2):389-95. Engler A, Stangler T, Willbold D. PMID: 11168374.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
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