Gary Huber

Title(s)	Project Scientist, Chemistry and Biochemistry
School	Vc-academic Affairs
Address	9500 Gilman Drive # La Jolla CA 92093
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Research

Research Activities and Funding

THEORETICAL STUDY OF TRIOSE PHOSPHATE ISOMERASE
NIH F32GM017862Mar 14, 1996
Role: Principal Investigator

Theory of Biomolecular Diffusion
NIH R01GM031749Jun 1, 1983 - Jun 30, 2023
Role: Co-Principal Investigator

Bibliographic

Publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.

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Multiscale computational modeling of the effects of 2'-deoxy-ATP on cardiac muscle calcium handling. J Appl Phys. 2023 Aug 21; 134(7):074905. Hock MT, Teitgen AE, McCabe KJ, Hirakis SP, Huber GA, Regnier M, Amaro RE, McCammon JA, McCulloch AD. PMID: 37601331; PMCID: PMC10435275.

View in: PubMed Mentions:
Investigating Intrinsically Disordered Proteins With Brownian Dynamics. Front Mol Biosci. 2022; 9:898838. Ahn SH, Huber GA, McCammon JA. PMID: 35755809; PMCID: PMC9213797.

View in: PubMed Mentions: 1
Multiscale Simulations Examining Glycan Shield Effects on Drug Binding to Influenza Neuraminidase. Biophys J. 2020 12 01; 119(11):2275-2289. Seitz C, Casalino L, Konecny R, Huber G, Amaro RE, McCammon JA. PMID: 33130120; PMCID: PMC7732775.

View in: PubMed Mentions: 9 Fields:
Bio Biophysics
Translation:Cells
Predicting the effects of dATP on cardiac contraction using multiscale modeling of the sarcomere. Arch Biochem Biophys. 2020 11 30; 695:108582. McCabe KJ, Aboelkassem Y, Teitgen AE, Huber GA, McCammon JA, Regnier M, McCulloch AD. PMID: 32956632; PMCID: PMC7721865.

View in: PubMed Mentions: 2 Fields:
Bio Biochemistry Bio Biophysics
Translation:Animals Cells
Brownian Dynamics Simulations of Biological Molecules. Trends Chem. 2019 Nov; 1(8):727-738. Huber GA, McCammon JA. PMID: 32309795; PMCID: PMC7164793.

View in: PubMed Mentions: 18
A Stochastic Multiscale Model of Cardiac Thin Filament Activation Using Brownian-Langevin Dynamics. Biophys J. 2019 12 17; 117(12):2255-2272. Aboelkassem Y, McCabe KJ, Huber GA, Regnier M, McCammon JA, McCulloch AD. PMID: 31547973; PMCID: PMC6990154.

View in: PubMed Mentions: 3 Fields:
Bio Biophysics
Translation:Cells
A Computational Assay that Explores the Hemagglutinin/Neuraminidase Functional Balance Reveals the Neuraminidase Secondary Site as a Novel Anti-Influenza Target. ACS Cent Sci. 2018 Nov 28; 4(11):1570-1577. Amaro RE, Ieong PU, Huber G, Dommer A, Steven AC, Bush RM, Durrant JD, Votapka LW. PMID: 30555910; PMCID: PMC6276040.

View in: PubMed Mentions: 14
HIERARCHICAL ORTHOGONAL MATRIX GENERATION AND MATRIX-VECTOR MULTIPLICATIONS IN RIGID BODY SIMULATIONS. SIAM J Sci Comput. 2018; 40(3):A1345-A1361. Fang F, Huang J, Huber G, McCammon JA, Zhang BO. PMID: 31452593; PMCID: PMC6709857.

View in: PubMed Mentions:
Brownian dynamic study of an enzyme metabolon in the TCA cycle: Substrate kinetics and channeling. Protein Sci. 2018 02; 27(2):463-471. Huang YM, Huber GA, Wang N, Minteer SD, McCammon JA. PMID: 29094409; PMCID: PMC5775167.

View in: PubMed Mentions: 16 Fields:
Bio Biochemistry
Translation:Animals Cells
Electrostatic Steering Accelerates C3d:CR2 Association. J Phys Chem B. 2016 08 25; 120(33):8416-23. Mohan RR, Huber GA, Morikis D. PMID: 27092816; PMCID: PMC5402296.

View in: PubMed Mentions: 3 Fields:
Che Chemistry
Translation:Cells
Hybrid finite element and Brownian dynamics method for charged particles. J Chem Phys. 2016 Apr 28; 144(16):164107. Huber GA, Miao Y, Zhou S, Li B, McCammon JA. PMID: 27131531; PMCID: PMC4851620.

View in: PubMed Mentions: Fields:
Bio Biophysics Che Chemistry Phy Physics
Electrostatic steering enhances the rate of cAMP binding to phosphodiesterase: Brownian dynamics modeling. Protein Sci. 2015 Nov; 24(11):1884-9. Huang YM, Huber G, McCammon JA. PMID: 26346301; PMCID: PMC4622220.

View in: PubMed Mentions: 6 Fields:
Bio Biochemistry
Translation:Cells
Electrostatic channeling in P. falciparum DHFR-TS: Brownian dynamics and Smoluchowski modeling. Biophys J. 2014 Nov 18; 107(10):2394-402. Metzger VT, Eun C, Kekenes-Huskey PM, Huber G, McCammon JA. PMID: 25418308; PMCID: PMC4241442.

View in: PubMed Mentions: 14 Fields:
Bio Biophysics
Translation:Animals Cells
Assessing the two-body diffusion tensor calculated by the bead models. J Chem Phys. 2013 May 28; 138(20):204117. Wang N, Huber GA, McCammon JA. PMID: 23742464; PMCID: PMC3683057.

View in: PubMed Mentions: 3 Fields:
Bio Biophysics Che Chemistry Phy Physics
Translation:Cells
Hybrid finite element and Brownian dynamics method for diffusion-controlled reactions. J Chem Phys. 2012 Apr 28; 136(16):164107. Bauler P, Huber GA, McCammon JA. PMID: 22559470; PMCID: PMC3350536.

View in: PubMed Mentions: 6 Fields:
Bio Biophysics Che Chemistry Phy Physics
Translation:Cells
Dynamics and calcium association to the N-terminal regulatory domain of human cardiac troponin C: a multiscale computational study. J Phys Chem B. 2012 Jul 26; 116(29):8449-59. Lindert S, Kekenes-Huskey PM, Huber G, Pierce L, McCammon JA. PMID: 22329450; PMCID: PMC3405770.

View in: PubMed Mentions: 35 Fields:
Che Chemistry
Translation:Humans Cells
Electrostatically biased binding of kinesin to microtubules. PLoS Biol. 2011 Nov; 9(11):e1001207. Grant BJ, Gheorghe DM, Zheng W, Alonso M, Huber G, Dlugosz M, McCammon JA, Cross RA. PMID: 22140358; PMCID: PMC3226556.

View in: PubMed Mentions: 38 Fields:
Bio Biology
Translation:Cells
Brownian dynamics study of the association between the 70S ribosome and elongation factor G. Biopolymers. 2011 Sep; 95(9):616-27. Dlugosz M, Huber GA, McCammon JA, Trylska J. PMID: 21394717; PMCID: PMC3125448.

View in: PubMed Mentions: 10 Fields:
Bio Biochemistry
Translation:Cells
Browndye: A Software Package for Brownian Dynamics. Comput Phys Commun. 2010 Nov 01; 181(11):1896-1905. Huber GA, McCammon JA. PMID: 21132109; PMCID: PMC2994412.

View in: PubMed Mentions: 49
Solvation Effect on the Conformations of Alanine Dipeptide: Integral Equation Approach. J Phys Chem Lett. 2010 Aug 05; 1(15):2279-2283. Ishizuka R, Huber GA, McCammon JA. PMID: 20694049; PMCID: PMC2916711.

View in: PubMed Mentions: 8 Fields:
Che Chemistry
Channeling by Proximity: The Catalytic Advantages of Active Site Colocalization Using Brownian Dynamics. J Phys Chem Lett. 2010 May 06; 1(9):1332-1335. Bauler P, Huber G, Leyh T, McCammon JA. PMID: 20454551; PMCID: PMC2865391.

View in: PubMed Mentions: 42 Fields:
Che Chemistry
Continuum simulations of acetylcholine consumption by acetylcholinesterase: a Poisson-Nernst-Planck approach. J Phys Chem B. 2008 Jan 17; 112(2):270-5. Zhou YC, Lu B, Huber GA, Holst MJ, McCammon JA. PMID: 18052268.

View in: PubMed Mentions: 10 Fields:
Che Chemistry
Electrodiffusion: a continuum modeling framework for biomolecular systems with realistic spatiotemporal resolution. J Chem Phys. 2007 Oct 07; 127(13):135102. Lu B, Zhou YC, Huber GA, Bond SD, Holst MJ, McCammon JA. PMID: 17919055.

View in: PubMed Mentions: 22 Fields:
Bio Biophysics Che Chemistry Phy Physics
Translation:Cells
Integrative biological modelling in silico. Novartis Found Symp. 2002; 247:4-19; discussion 20-5, 84-90, 244-52. McCulloch AD, Huber G. PMID: 12539946.

View in: PubMed Mentions: 2 Fields:
Med Medicine (General)
Translation:Humans Animals