Our site may be slower due to heavy traffic from automated "bots" and AI crawlers. We're working to fix this.

Shu Chien

Title(s)Recall Faculty, Bioengineering
SchoolVc-academic Affairs
Address9500 Gilman Drive #
La Jolla CA 92093
vCardDownload vCard

    Collapse Research 
    Collapse research activities and funding
    Locus-specific Imaging of Dynamic Histone Methylations during Reprogramming
    NIH R01GM125379Aug 3, 2017 - Apr 30, 2021
    Role: Co-Principal Investigator
    The second phase of NIH Common Fund 4D Nucleome Network Organizational Hub
    NIH U01CA200147Sep 1, 2015 - Aug 31, 2025
    Role: Principal Investigator
    Role of Spatiotemporal Epigenetic Dynamics in Regulating Endothelial Gene Expressions under Flows
    NIH R01HL121365Dec 20, 2013 - Nov 30, 2021
    Role: Principal Investigator
    Systems Biology Analyses for Hemodynamic Regulation of Vascular Homeostasis
    NIH R01HL108735Aug 24, 2012 - Jul 31, 2025
    Role: Principal Investigator
    Nucleolin Regulation of miRome by Shear Stress
    NIH R01HL106579Jan 1, 2011 - Nov 30, 2022
    Role: Principal Investigator
    Integrative Bioengineering of Heart, Vessels, and Blood
    NIH T32HL105373Sep 20, 2010 - Aug 31, 2021
    Role: Principal Investigator
    Optimization of the Chemical-Physical Environments for Stem Cell Differentiation
    NIH R21HL104402Jul 1, 2010 - Jun 30, 2012
    Role: Principal Investigator
    UCSD MARC Program
    NIH T34GM087193Jun 1, 2009 - May 31, 2015
    Role: Principal Investigator
    Confocal Laser Scanning Biological Microscope Olympus Fv1000
    NIH S10RR025630Apr 1, 2009 - Mar 31, 2010
    Role: Principal Investigator
    The Role of Phosphatases in EC Mechanotransduction
    NIH R01HL085159Jul 1, 2006 - Jun 30, 2011
    Role: Principal Investigator
    Mechanical Feedback on Cell Structure and Signaling
    NIH R01HL080518Feb 1, 2006 - Jan 31, 2011
    Role: Principal Investigator
    DETECTION AND MODELS OF TOXICANT EXPOSURE
    NIH P42ES010337Jul 1, 2000 - Mar 31, 2022
    Role: Co-Investigator
    MECHANISMS OF REPERFUSION INDUCTION OF ROS AND IKK
    NIH R01HL062747Feb 8, 2000 - Jan 31, 2004
    Role: Principal Investigator
    Mechanical and Molecular Bases of Endothelial Remodeling
    NIH R01HL064382Sep 28, 1999 - Jul 31, 2011
    Role: Principal Investigator
    1997 BIOMEDICAL ENGINEERING SOCIETY FALL MEETING
    NIH R13HL058979Sep 1, 1997 - Aug 31, 1998
    Role: Principal Investigator
    Biomechanics of the Heart, Vessels, and Blood Cells
    NIH P01HL043026Jul 1, 1990 - May 31, 2007
    Role: Principal Investigator
    BLOOD CELL PROPERTIES AND CIRCULATORY REGULATION
    NIH R37HL044147May 1, 1989 - Apr 30, 2000
    Role: Principal Investigator
    RHEOLOGY IN CARDIOVASCULAR DISEASES
    NIH T32HL007114Jul 1, 1980 - Aug 31, 1990
    Role: Principal Investigator
    HUMAN BLOOD CELL MEMBRANES IN HEALTH AND DISEASE
    NIH P01HL016851Jun 1, 1979 - May 31, 1990
    Role: Principal Investigator
    Molecular Mechanism of Endothelial Migration Under Flow
    NIH R01HL019454Dec 1, 1976 - Jun 30, 2006
    Role: Principal Investigator
    Cardiovascular Engineering Science
    NIH T32HL007089Jul 1, 1975 - Oct 3, 2012
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Active drug-safety monitoring and management in the treatment of rifampicin-resistant tuberculosis: a nationwide multicenter prospective study. J Microbiol Immunol Infect. 2025 Jul 30. Lin CJ, Lin CB, Chien ST, Huang YW, Lee JJ, Lee CH, Yu MC, Chiang CY. PMID: 40759626.
      View in: PubMed   Mentions:    Fields:    
    2. Using technology acceptance model to explore physicians' perspectives of clinical decision support system alerts. BMJ Health Care Inform. 2025 Jun 26; 32(1). Chien SC, Chien CH, Chen CY, Chien PH, Hsu CK, Yang HC, Li YC. PMID: 40578848; PMCID: PMC12207143.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    3. Temporal single-cell sequencing analysis reveals that GPNMB-expressing macrophages potentiate muscle regeneration. Exp Mol Med. 2025 Jun; 57(6):1232-1245. Chen YF, Lee CW, Li YJ, Lin WT, Chen HY, Chen YC, Lin CH, Ho JH, Lu LF, Chien S, Lee OK. PMID: 40490493; PMCID: PMC12229484.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    4. Real-World Data on the Associations of Tricyclic Antidepressants and Selective Serotonin Reuptake Inhibitors with Gynecologic Cancer Risk. Cancers (Basel). 2025 May 10; 17(10). Wang CH, Huang CW, Nguyen NTH, Lin MC, Nguyen PA, Islam MM, Chien SC, Yang HC. PMID: 40427115; PMCID: PMC12109922.
      View in: PubMed   Mentions:
    5. Pulsatile flow induces chromatin interaction with lamin-associated proteins to enrich H3K9 methylation in endothelial cells. Proc Natl Acad Sci U S A. 2025 Mar 25; 122(12):e2424566122. Chen LJ, Li JY, Nguyen P, Norwich G, Wang Y, Teng D, Shiu YT, Shyy JYJ, Chien S. PMID: 40117319; PMCID: PMC11962468.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    6. Silencing KRIT1 Partially Reverses the Effects of Disturbed Flow on the Endothelial Cell Transcriptome. bioRxiv. 2025 Mar 14. Meecham A, McCurdy S, Frias-Anaya E, Li W, Gallego-Gutierrez H, Ngyuen P, Li JY, Chien S, Shyy JY, Ginsberg MH, Lopez-Ramirez MA. PMID: 40161739; PMCID: PMC11952409.
      View in: PubMed   Mentions:
    7. Use of Artificial Intelligence, Internet of Things, and Edge Intelligence in Long-Term Care for Older People: Comprehensive Analysis Through Bibliometric, Google Trends, and Content Analysis. J Med Internet Res. 2025 Mar 04; 27:e56692. Chien SC, Yen CM, Chang YH, Chen YE, Liu CC, Hsiao YP, Yang PY, Lin HM, Yang TE, Lu XH, Wu IC, Hsu CC, Chiou HY, Chung RH. PMID: 40053718; PMCID: PMC11920668.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    8. Ultrasound Control of Genomic Regulatory Toolboxes for Cancer Immunotherapy. Nat Commun. 2024 12 01; 15(1):10444. Wu Y, Huang Z, Liu Y, He P, Wang Y, Yan L, Wang X, Gao S, Zhou X, Yoon CW, Sun K, Situ Y, Ho P, Zeng Y, Yuan Z, Zhu L, Zhou Q, Zhao Y, Liu T, Kwong GA, Chien S, Liu L, Wang Y. PMID: 39617755; PMCID: PMC11609292.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    9. Clofazimine and QT prolongation in the treatment of rifampicin-resistant tuberculosis: Findings of aDSM in Taiwan. J Microbiol Immunol Infect. 2024 Oct; 57(5):791-800. Lin CJ, Chen JH, Chien ST, Huang YW, Lin CB, Lee JJ, Lee CH, Yu MC, Chiang CY. PMID: 39160114.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    10. Using large language model (LLM) to identify high-burden informal caregivers in long-term care. Comput Methods Programs Biomed. 2024 Oct; 255:108329. Chien SC, Yen CM, Chang YH, Chen YE, Liu CC, Hsiao YP, Yang PY, Lin HM, Yang TE, Lu XH, Wu IC, Hsu CC, Chiou HY, Chung RH. PMID: 39029418.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    11. Understanding and alleviating informal caregiver burden through the development and validation of a caregiver strain index-based model in Taiwan. BMC Geriatr. 2024 Jun 26; 24(1):558. Chien SC, Chang YH, Yen CM, Chen YE, Liu CC, Hsiao YP, Yang PY, Lin HM, Yang TE, Lu XH, Wu IC, Hsu CC, Chiou HY, Chung RH. PMID: 38918715; PMCID: PMC11200844.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    12. Corrigendum to "Investigating nurses' acceptance of patients' bring your own device implementation in a clinical setting: A pilot study" [Asia-Pacific J Oncol Nurs 10 (2023) 100195]. Asia Pac J Oncol Nurs. 2024 May; 11(5):100437. Chien SC, Chen CY, Chien CH, Iqbal U, Yang HC, Hsueh HC, Weng SF, Jian WS. PMID: 38812673; PMCID: PMC11134532.
      View in: PubMed   Mentions:
    13. Mitigating treatment failure of pulmonary pre-extensively drug-resistant tuberculosis: The role of new and repurposed drugs. J Microbiol Immunol Infect. 2024 Aug; 57(4):617-628. Huang YW, Yu MC, Lin CB, Lee JJ, Lin CJ, Chien ST, Lee CH, Chiang CY. PMID: 38705821.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    14. A novel Multi-Level Refined (MLR) knowledge graph design and chatbot system for healthcare applications. PLoS One. 2024; 19(1):e0296939. Hsueh HC, Chien SC, Huang CW, Yang HC, Iqbal U, Lin LF, Jian WS. PMID: 38295121; PMCID: PMC10829983.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    15. Radiographic characteristics of rifampicin-resistant tuberculosis in the STREAM stage 1 trial and their influence on time to culture conversion in the short regimen. BMC Infect Dis. 2024 Jan 30; 24(1):144. Chiang CY, Bern H, Goodall R, Chien ST, Rusen ID, Nunn A, STREAM Sub-study Collaborators. PMID: 38291393; PMCID: PMC10825976.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCTClinical Trials
    16. Single-cell RNA sequencing unveils unique transcriptomic signatures of endothelial cells and role of ENO1 in response to disturbed flow. Proc Natl Acad Sci U S A. 2024 Jan 30; 121(5):e2318904121. Chen LJ, Li JY, Nguyen P, He M, Chen ZB, Subramaniam S, Shyy JY, Chien S. PMID: 38261622; PMCID: PMC10835041.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    17. Exploring concepts and trends in informal caregiver burden: systematic review using citation network and content analysis. Aging Clin Exp Res. 2023 Dec; 35(12):2873-2885. Chien SC, Chang YH, Yen CM, Onthoni DD, Wu IC, Hsu CC, Chiou HY, Chung RH. PMID: 37907665.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    18. Incremental yield of serial sputum examinations in the diagnosis of pulmonary tuberculosis in Taiwan: Findings of a pragmatic trial. J Microbiol Immunol Infect. 2023 Dec; 56(6):1245-1252. Chiang CY, Lin CB, Chien ST, Wang CH, Huang YW, Huang WC, Yu MC, Lee JJ, Rieder HL. PMID: 37802687.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    19. Predicting Long-Term Care Service Demands for Cancer Patients: A Machine Learning Approach. Cancers (Basel). 2023 Sep 16; 15(18). Chien SC, Chang YH, Yen CM, Chen YE, Liu CC, Hsiao YP, Yang PY, Lin HM, Lu XH, Wu IC, Hsu CC, Chiou HY, Chung RH. PMID: 37760567; PMCID: PMC10526410.
      View in: PubMed   Mentions: 2  
    20. Risk factor analysis of postoperative complications after adjunctive pulmonary resection in patients with multidrug-resistant tuberculosis: A multi-institutional study. J Microbiol Immunol Infect. 2023 Oct; 56(5):1064-1072. Huang WL, Chien ST, Yu MC, Chang BS, Yen YT, Wu MH, Tseng YL. PMID: 37586914.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    21. Celebrating the inauguration of "Mechanobiology in Medicine". Mechanobiol Med. 2023 Sep; 1(1):100004. Chien S. PMID: 40395870; PMCID: PMC12082132.
      View in: PubMed   Mentions:
    22. Using alert dwell time to filter universal clinical alerts: A machine learning approach. Comput Methods Programs Biomed. 2023 Oct; 240:107696. Chien SC, Yang HC, Chen CY, Chien CH, Hsu CK, Chien PH, Li YJ. PMID: 37480643.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    23. Epitranscriptional Regulation: From the Perspectives of Cardiovascular Bioengineering. Annu Rev Biomed Eng. 2023 06 08; 25:157-184. Chen ZB, He M, Li JY, Shyy JY, Chien S. PMID: 36913673.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    24. Renin-Angiotensin-Aldosterone System Inhibitors and Development of Gynecologic Cancers: A 23 Million Individual Population-Based Study. Int J Mol Sci. 2023 Feb 14; 24(4). Nguyen NTH, Nguyen PA, Huang CW, Wang CH, Lin MC, Hsu MH, Bao HB, Chien SC, Yang HC. PMID: 36835224; PMCID: PMC9968233.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    25. Investigating nurses' acceptance of patients' bring your own device implementation in a clinical setting: A pilot study. Asia Pac J Oncol Nurs. 2023 Mar; 10(3):100195. Chien SC, Chen CY, Chien CH, Iqbal U, Yang HC, Hsueh HC, Weng SF, Jian WS. PMID: 36915387; PMCID: PMC10006526.
      View in: PubMed   Mentions: 2  
    26. Mechanosensor Piezo1 mediates bimodal patterns of intracellular calcium and FAK signaling. EMBO J. 2022 09 01; 41(17):e111799. Pan Y, Shi LZ, Yoon CW, Preece D, Gomez-Godinez V, Lu S, Carmona C, Woo SH, Chien S, Berns MW, Liu L, Wang Y. PMID: 35844093; PMCID: PMC9433934.
      View in: PubMed   Mentions: 15     Fields:    Translation:Cells
    27. Alerts in Clinical Decision Support Systems (CDSS): A Bibliometric Review and Content Analysis. Healthcare (Basel). 2022 Mar 23; 10(4). Chien SC, Chen YL, Chien CH, Chin YP, Yoon CH, Chen CY, Yang HC, Li YJ. PMID: 35455779; PMCID: PMC9028311.
      View in: PubMed   Mentions: 7  
    28. Biomechanical interactions of Schistosoma mansoni eggs with vascular endothelial cells facilitate egg extravasation. PLoS Pathog. 2022 03; 18(3):e1010309. Yeh YT, Skinner DE, Criado-Hidalgo E, Chen NS, Garcia-De Herreros A, El-Sakkary N, Liu L, Zhang S, Kandasamy A, Chien S, Lasheras JC, Del Álamo JC, Caffrey CR. PMID: 35316298; PMCID: PMC8939816.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    29. Performance of Nucleic Acid Amplification Tests in Patients with Presumptive Pulmonary Tuberculosis in Taiwan. Infect Dis Ther. 2022 Apr; 11(2):871-885. Huang WC, Lin CB, Chien ST, Wang JY, Lin CJ, Feng JY, Lee CH, Shu CC, Yu MC, Lee JJ, Chiang CY. PMID: 35254635; PMCID: PMC8900096.
      View in: PubMed   Mentions: 3  
    30. Voice-based control system for smart hospital wards: a pilot study of patient acceptance. BMC Health Serv Res. 2022 Mar 03; 22(1):287. Jian WS, Wang JY, Rahmanti AR, Chien SC, Hsu CK, Chien CH, Li YC, Chen CY, Chin YP, Huang CL. PMID: 35236341; PMCID: PMC8892698.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    31. Monocytes engineered with iSNAP inhibit human B-lymphoma progression. Bioeng Transl Med. 2022 May; 7(2):e10285. Wu H, Amirfakhri S, Lin HH, Hollandsworth H, Filemoni F, Liu Y, Wu Y, Li JYS, Xu H, Chien S, Bouvet M, Wang Y. PMID: 35600645; PMCID: PMC9115687.
      View in: PubMed   Mentions: 2  
    32. Correlation Between Previous Caesarean Section and Adverse Maternal Outcomes Accordingly With Robson Classification: Systematic Review and Meta-Analysis. Front Med (Lausanne). 2021; 8:740000. Jamshed S, Chien SC, Tanweer A, Asdary RN, Hardhantyo M, Greenfield D, Chien CH, Weng SF, Jian WS, Iqbal U. PMID: 35096855; PMCID: PMC8795992.
      View in: PubMed   Mentions: 4  
    33. Vitexin inhibits APEX1 to counteract the flow-induced endothelial inflammation. Proc Natl Acad Sci U S A. 2021 11 30; 118(48). Zhao CR, Yang FF, Cui Q, Wang D, Zhou Y, Li YS, Zhang YP, Tang RZ, Yao WJ, Wang X, Pang W, Zhao JN, Jiang ZT, Zhu JJ, Chien S, Zhou J. PMID: 34810252; PMCID: PMC8640790.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    34. Integration of FRET and sequencing to engineer kinase biosensors from mammalian cell libraries. Nat Commun. 2021 08 19; 12(1):5031. Liu L, Limsakul P, Meng X, Huang Y, Harrison RES, Huang TS, Shi Y, Yu Y, Charupanit K, Zhong S, Lu S, Zhang J, Chien S, Sun J, Wang Y. PMID: 34413312; PMCID: PMC8376904.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    35. Control of the activity of CAR-T cells within tumours via focused ultrasound. Nat Biomed Eng. 2021 11; 5(11):1336-1347. Wu Y, Liu Y, Huang Z, Wang X, Jin Z, Li J, Limsakul P, Zhu L, Allen M, Pan Y, Bussell R, Jacobson A, Liu T, Chien S, Wang Y. PMID: 34385696; PMCID: PMC9015817.
      View in: PubMed   Mentions: 108     Fields:    Translation:AnimalsCells
    36. Life with FASEB for three decades. FASEB Bioadv. 2021 Oct; 3(10):814-828. Chien S. PMID: 34632316; PMCID: PMC8493971.
      View in: PubMed   Mentions: 1  
    37. Continuous monitoring of deep-tissue haemodynamics with stretchable ultrasonic phased arrays. Nat Biomed Eng. 2021 07; 5(7):749-758. Wang C, Qi B, Lin M, Zhang Z, Makihata M, Liu B, Zhou S, Huang YH, Hu H, Gu Y, Chen Y, Lei Y, Lee T, Chien S, Jang KI, Kistler EB, Xu S. PMID: 34272524.
      View in: PubMed   Mentions: 56     Fields:    Translation:Humans
    38. The interplay between matrix deformation and the coordination of turning events governs directed neutrophil migration in 3D matrices. Sci Adv. 2021 Jul; 7(29). François J, Kandasamy A, Yeh YT, Schwartz A, Ayala C, Meili R, Chien S, Lasheras JC, Del Álamo JC. PMID: 34261650; PMCID: PMC8279509.
      View in: PubMed   Mentions: 6     Fields:    
    39. The Effectiveness and Safety of Immune Checkpoint Inhibitors in Non-Small Cell Lung Cancer Patients With Stage III/IV: A Multicenter Study. Front Oncol. 2021; 11:671127. Hsu JC, Nguyen PA, Chen YT, Yang SC, Lin CC, Yang YH, Lin YC, Hsia TC, Hsieh HC, Wu JS, Chang CP, Feng YH, Lin PC, Hsu PC, Tzeng HE, Chien SC, Chang WC, Chang CC, Yang HC, Lee CM, Lu CY. PMID: 34307141; PMCID: PMC8293991.
      View in: PubMed   Mentions: 1  
    40. Roles of KLF4 and AMPK in the inhibition of glycolysis by pulsatile shear stress in endothelial cells. Proc Natl Acad Sci U S A. 2021 05 25; 118(21). Han Y, He M, Marin T, Shen H, Wang WT, Lee TY, Hong HC, Jiang ZL, Garland T, Shyy JY, Gongol B, Chien S. PMID: 34001623; PMCID: PMC8166073.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    41. Application of Artificial Intelligence in COVID-19 Pandemic: Bibliometric Analysis. Healthcare (Basel). 2021 Apr 09; 9(4). Islam MM, Poly TN, Alsinglawi B, Lin LF, Chien SC, Liu JC, Jian WS. PMID: 33918686; PMCID: PMC8070493.
      View in: PubMed   Mentions: 16  
    42. Elucidating the Biomechanics of Leukocyte Transendothelial Migration by Quantitative Imaging. Front Cell Dev Biol. 2021; 9:635263. Schwartz AB, Campos OA, Criado-Hidalgo E, Chien S, Del Álamo JC, Lasheras JC, Yeh YT. PMID: 33855018; PMCID: PMC8039384.
      View in: PubMed   Mentions: 14  
    43. Assessment of knowledge, attitudes, and practices towards Zika virus among healthcare workers in St. Kitts. BMC Infect Dis. 2021 Mar 05; 21(1):237. Francis DL, Wongsin U, Chien SC, Hsu YE, Lohmeyer FM, Jian WS, Lin LF, Iqbal U. PMID: 33663410; PMCID: PMC7934413.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    44. A novel method to retrieve alerts from a homegrown Computerized Physician Order Entry (CPOE) system of an academic medical center: Comprehensive alert characteristic analysis. PLoS One. 2021; 16(2):e0246597. Chien SC, Chin YH, Yoon CH, Islam MM, Jian WS, Hsu CK, Chen CY, Chien PH, Li YJ. PMID: 33561178; PMCID: PMC7872273.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    45. Circulating level of microRNA-142-5p is a potential biomarker for predicting in-stent restenosis: a case-control study. BMC Cardiovasc Disord. 2021 02 08; 21(1):77. Pan CH, Chien SC, Chen CJ, Shih CM, Hsieh MH, Huang CY, Bi WF, Chan CS, Kao YT, Hsiao CY, Chiang SJ, Chiang KH, Huang JH, Liu YR, Luo JD, Huang HY, Wu CH. PMID: 33557763; PMCID: PMC7869494.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    46. Longitudinal shear stress response in human endothelial cells to atheroprone and atheroprotective conditions. Proc Natl Acad Sci U S A. 2021 01 26; 118(4). Maurya MR, Gupta S, Li JY, Ajami NE, Chen ZB, Shyy JY, Chien S, Subramaniam S. PMID: 33468662; PMCID: PMC7848718.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansCells
    47. Reply to Verwilt et al.: Experimental evidence against DNA contamination in SILVER-seq. Proc Natl Acad Sci U S A. 2020 08 11; 117(32):18937-18938. Zhou Z, Wu Q, Yan Z, Zheng H, Chen CJ, Liu Y, Qi Z, Calandrelli R, Chen Z, Chien S, Su HI, Zhong S. PMID: 32788395; PMCID: PMC7431041.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    48. Mutual-Aid Mobile App for Emergency Care: Feasibility Study. JMIR Form Res. 2020 Mar 19; 4(3):e15494. Chien SC, Islam MM, Yeh CA, Chien PH, Chen CY, Chin YP, Lin MC. PMID: 32191212; PMCID: PMC7118550.
      View in: PubMed   Mentions: 1     Fields:    
    49. Engineering light-controllable CAR T cells for cancer immunotherapy. Sci Adv. 2020 02; 6(8):eaay9209. Huang Z, Wu Y, Allen ME, Pan Y, Kyriakakis P, Lu S, Chang YJ, Wang X, Chien S, Wang Y. PMID: 32128416; PMCID: PMC7030928.
      View in: PubMed   Mentions: 83     Fields:    Translation:HumansAnimalsCells
    50. Reply to Hartl and Gao: Lack of between-batch difference in the distributions of measured extracellular RNA levels. Proc Natl Acad Sci U S A. 2020 01 28; 117(4):1851-1852. Zhou Z, Wu Q, Yan Z, Zheng H, Chen CJ, Liu Y, Qi Z, Calandrelli R, Chen Z, Chien S, Su HI, Zhong S. PMID: 31964851; PMCID: PMC6995027.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    51. Incidences of Hypothyroidism Associated With Surgical Procedures for Thyroid Disorders: A Nationwide Population-Based Study. Front Pharmacol. 2019; 10:1378. Tsai SH, Chien SC, Nguyen PA, Chien PH, Ma HP, Asdary RN, Wang YC, Humayun A, Huang CL, Iqbal U, Jian WS. PMID: 31920634; PMCID: PMC6920095.
      View in: PubMed   Mentions: 2  
    52. Association Between Atrial Fibrillation and Dementia: A Meta-Analysis. Front Aging Neurosci. 2019; 11:305. Islam MM, Poly TN, Walther BA, Yang HC, Wu CC, Lin MC, Chien SC, Li YC. PMID: 31780919; PMCID: PMC6857071.
      View in: PubMed   Mentions: 26  
    53. Mapping RNA-chromatin interactions by sequencing with iMARGI. Nat Protoc. 2019 11; 14(11):3243-3272. Wu W, Yan Z, Nguyen TC, Bouman Chen Z, Chien S, Zhong S. PMID: 31619811; PMCID: PMC7314528.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCells
    54. Extracellular MicroRNA-92a Mediates Endothelial Cell-Macrophage Communication. Arterioscler Thromb Vasc Biol. 2019 12; 39(12):2492-2504. Chang YJ, Li YS, Wu CC, Wang KC, Huang TC, Chen Z, Chien S. PMID: 31597449; PMCID: PMC6879873.
      View in: PubMed   Mentions: 64     Fields:    Translation:HumansAnimalsCells
    55. Does long-term use of antidiabetic drugs changes cancer risk? Medicine (Baltimore). 2019 Oct; 98(40):e17461. Liu YC, Nguyen PA, Humayun A, Chien SC, Yang HC, Asdary RN, Syed-Abdul S, Hsu MH, Moldovan M, Yen Y, Li YJ, Jian WS, Iqbal U. PMID: 31577776; PMCID: PMC6783244.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    56. Extracellular RNA in a single droplet of human serum reflects physiologic and disease states. Proc Natl Acad Sci U S A. 2019 09 17; 116(38):19200-19208. Zhou Z, Wu Q, Yan Z, Zheng H, Chen CJ, Liu Y, Qi Z, Calandrelli R, Chen Z, Chien S, Su HI, Zhong S. PMID: 31481608; PMCID: PMC6754586.
      View in: PubMed   Mentions: 39     Fields:    Translation:Humans
    57. Dr. Y. C. Fung's Contributions to Biomechanics, Bioengineering, and Humanity: Warmest Celebration for a Magnificent Centenarian. J Biomech Eng. 2019 Sep 01; 141(9). Chien S. PMID: 31215621.
      View in: PubMed   Mentions: 1     Fields:    
    58. Shear stress regulation of miR-93 and miR-484 maturation through nucleolin. Proc Natl Acad Sci U S A. 2019 06 25; 116(26):12974-12979. Gongol B, Marin T, Zhang J, Wang SC, Sun W, He M, Chen S, Chen L, Li J, Liu JH, Martin M, Han Y, Kang J, Johnson DA, Lytle C, Li YS, Huang PH, Chien S, Shyy JY. PMID: 31182601; PMCID: PMC6600934.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    59. Association of endothelin genetic variants and hospitalized infection complications in end-stage renal disease (ESRD) patients. BMC Nephrol. 2019 06 05; 20(1):203. Kao CC, Cheng SY, Wang YJ, Chien SC, Hsu YW, Wu MY, Lu HF, Nam S, Sun T, Wu MS, Chang WC. PMID: 31167651; PMCID: PMC6549338.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    60. The development and use of a pharmacist-specific Mini-CEX for postgraduate year trainees in Taiwan. BMC Med Educ. 2019 May 22; 19(1):165. Wei CJ, Lu TH, Chien SC, Huang WT, Liu YP, Chan CY, Chiu CH. PMID: 31118004; PMCID: PMC6530012.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    61. Atheroprotective Flow Upregulates ITPR3 (Inositol 1,4,5-Trisphosphate Receptor 3) in Vascular Endothelium via KLF4 (Krüppel-Like Factor 4)-Mediated Histone Modifications. Arterioscler Thromb Vasc Biol. 2019 05; 39(5):902-914. He M, Huang TS, Li S, Hong HC, Chen Z, Martin M, Zhou X, Huang HY, Su SH, Zhang J, Wang WT, Kang J, Huang HD, Zhang J, Chien S, Shyy JY. PMID: 30917677; PMCID: PMC6536300.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansAnimalsCells
    62. Impact of universal drug susceptibility testing and effective management of multidrug-resistant tuberculosis in Taiwan. PLoS One. 2019; 14(4):e0214792. Lee PH, Chan PC, Peng YT, Chu PW, Wu MH, Jou R, Yu MC, Lin CJ, Huang YW, Chien ST, Lee JJ, Chiang CY. PMID: 30939150; PMCID: PMC6445419.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    63. MiR-145 mediates cell morphology-regulated mesenchymal stem cell differentiation to smooth muscle cells. Biomaterials. 2019 06; 204:59-69. Yeh YT, Wei J, Thorossian S, Nguyen K, Hoffman C, Del Álamo JC, Serrano R, Li YJ, Wang KC, Chien S. PMID: 30884320; PMCID: PMC6825513.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    64. Genome-wide colocalization of RNA-DNA interactions and fusion RNA pairs. Proc Natl Acad Sci U S A. 2019 02 19; 116(8):3328-3337. Yan Z, Huang N, Wu W, Chen W, Jiang Y, Chen J, Huang X, Wen X, Xu J, Jin Q, Zhang K, Chen Z, Chien S, Zhong S. PMID: 30718424; PMCID: PMC6386723.
      View in: PubMed   Mentions: 45     Fields:    Translation:Humans
    65. Coordinated histone modifications and chromatin reorganization in a single cell revealed by FRET biosensors. Proc Natl Acad Sci U S A. 2018 12 11; 115(50):E11681-E11690. Peng Q, Lu S, Shi Y, Pan Y, Limsakul P, Chernov AV, Qiu J, Chai X, Shi Y, Wang P, Ji Y, Li YJ, Strongin AY, Verkhusha VV, Izpisua Belmonte JC, Ren B, Wang Y, Chien S, Wang Y. PMID: 30478057; PMCID: PMC6294946.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCells
    66. RAP2 mediates mechanoresponses of the Hippo pathway. Nature. 2018 08; 560(7720):655-660. Meng Z, Qiu Y, Lin KC, Kumar A, Placone JK, Fang C, Wang KC, Lu S, Pan M, Hong AW, Moroishi T, Luo M, Plouffe SW, Diao Y, Ye Z, Park HW, Wang X, Yu FX, Chien S, Wang CY, Ren B, Engler AJ, Guan KL. PMID: 30135582; PMCID: PMC6128698.
      View in: PubMed   Mentions: 197     Fields:    Translation:HumansAnimalsCells
    67. Effectiveness and Safety of Standard- and Low-Dose Rivaroxaban in Asians With Atrial Fibrillation. J Am Coll Cardiol. 2018 07 31; 72(5):477-485. Lin YC, Chien SC, Hsieh YC, Shih CM, Lin FY, Tsao NW, Chen CW, Kao YT, Chiang KH, Chen WT, Chien LN, Huang CY. PMID: 30049307.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    68. Treatment Outcomes of Multidrug-Resistant Tuberculosis in Taiwan: Tackling Loss to Follow-up. Clin Infect Dis. 2018 07 02; 67(2):202-210. Yu MC, Chiang CY, Lee JJ, Chien ST, Lin CJ, Lee SW, Lin CB, Yang WT, Wu YH, Huang YW. PMID: 29394358; PMCID: PMC6030934.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    69. Health Care Costs and Utilization of Dabigatran Compared With Warfarin for Secondary Stroke Prevention in Patients With Nonvalvular Atrial Fibrillation: A Retrospective Population Study. Med Care. 2018 05; 56(5):410-415. Chi NF, Wang Y, Chien LN, Chien SC, Ko Y. PMID: 29578954.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansPHPublic Health
    70. Enhancer-associated long non-coding RNA LEENE regulates endothelial nitric oxide synthase and endothelial function. Nat Commun. 2018 01 18; 9(1):292. Miao Y, Ajami NE, Huang TS, Lin FM, Lou CH, Wang YT, Li S, Kang J, Munkacsi H, Maurya MR, Gupta S, Chien S, Subramaniam S, Chen Z. PMID: 29348663; PMCID: PMC5773557.
      View in: PubMed   Mentions: 86     Fields:    Translation:HumansAnimalsCells
    71. Mechanogenetics for the remote and noninvasive control of cancer immunotherapy. Proc Natl Acad Sci U S A. 2018 01 30; 115(5):992-997. Pan Y, Yoon S, Sun J, Huang Z, Lee C, Allen M, Wu Y, Chang YJ, Sadelain M, Shung KK, Chien S, Wang Y. PMID: 29343642; PMCID: PMC5798350.
      View in: PubMed   Mentions: 126     Fields:    Translation:HumansAnimalsCells
    72. Thy-1 dependent uptake of mesenchymal stem cell-derived extracellular vesicles blocks myofibroblastic differentiation. Sci Rep. 2017 12 22; 7(1):18052. Shentu TP, Huang TS, Cernelc-Kohan M, Chan J, Wong SS, Espinoza CR, Tan C, Gramaglia I, van der Heyde H, Chien S, Hagood JS. PMID: 29273797; PMCID: PMC5741716.
      View in: PubMed   Mentions: 62     Fields:    Translation:HumansCells
    73. Three-dimensional forces exerted by leukocytes and vascular endothelial cells dynamically facilitate diapedesis. Proc Natl Acad Sci U S A. 2018 01 02; 115(1):133-138. Yeh YT, Serrano R, François J, Chiu JJ, Li YJ, Del Álamo JC, Chien S, Lasheras JC. PMID: 29255056; PMCID: PMC5776826.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansCells
    74. Nanoparticle Functionalization with Platelet Membrane Enables Multifactored Biological Targeting and Detection of Atherosclerosis. ACS Nano. 2018 01 23; 12(1):109-116. Wei X, Ying M, Dehaini D, Su Y, Kroll AV, Zhou J, Gao W, Fang RH, Chien S, Zhang L. PMID: 29216423; PMCID: PMC5859122.
      View in: PubMed   Mentions: 99     Fields:    Translation:HumansAnimalsCells
    75. Systems biology analysis of longitudinal functional response of endothelial cells to shear stress. Proc Natl Acad Sci U S A. 2017 10 10; 114(41):10990-10995. Ajami NE, Gupta S, Maurya MR, Nguyen P, Li JY, Shyy JY, Chen Z, Chien S, Subramaniam S. PMID: 28973892; PMCID: PMC5642700.
      View in: PubMed   Mentions: 81     Fields:    Translation:HumansCells
    76. Engineered proteins with sensing and activating modules for automated reprogramming of cellular functions. Nat Commun. 2017 09 07; 8(1):477. Sun J, Lei L, Tsai CM, Wang Y, Shi Y, Ouyang M, Lu S, Seong J, Kim TJ, Wang P, Huang M, Xu X, Nizet V, Chien S, Wang Y. PMID: 28883531; PMCID: PMC5589908.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    77. Associations of genetic variants of endothelin with cardiovascular complications in patients with renal failure. BMC Nephrol. 2017 Sep 07; 18(1):291. Kao CC, Cheng SY, Wu MY, Chien SC, Lu HF, Hsu YW, Zhang YF, Wu MS, Chang WC. PMID: 28882114; PMCID: PMC5590196.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    78. VAMP3 and SNAP23 mediate the disturbed flow-induced endothelial microRNA secretion and smooth muscle hyperplasia. Proc Natl Acad Sci U S A. 2017 08 01; 114(31):8271-8276. Zhu JJ, Liu YF, Zhang YP, Zhao CR, Yao WJ, Li YS, Wang KC, Huang TS, Pang W, Wang XF, Wang X, Chien S, Zhou J. PMID: 28716920; PMCID: PMC5547597.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
    79. LINC00341 exerts an anti-inflammatory effect on endothelial cells by repressing VCAM1. Physiol Genomics. 2017 Jul 01; 49(7):339-345. Huang TS, Wang KC, Quon S, Nguyen P, Chang TY, Chen Z, Li YS, Subramaniam S, Shyy J, Chien S. PMID: 28500253; PMCID: PMC5538877.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCells
    80. Epigenetic Regulation: A New Frontier for Biomedical Engineers. Annu Rev Biomed Eng. 2017 06 21; 19:195-219. Chen Z, Li S, Subramaniam S, Shyy JY, Chien S. PMID: 28301736.
      View in: PubMed   Mentions: 78     Fields:    Translation:HumansAnimalsCells
    81. MicroRNA-10a is crucial for endothelial response to different flow patterns via interaction of retinoid acid receptors and histone deacetylases. Proc Natl Acad Sci U S A. 2017 02 21; 114(8):2072-2077. Lee DY, Lin TE, Lee CI, Zhou J, Huang YH, Lee PL, Shih YT, Chien S, Chiu JJ. PMID: 28167758; PMCID: PMC5338411.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimalsCells
    82. TIFA as a crucial mediator for NLRP3 inflammasome. Proc Natl Acad Sci U S A. 2016 12 27; 113(52):15078-15083. Lin TY, Wei TW, Li S, Wang SC, He M, Martin M, Zhang J, Shentu TP, Xiao H, Kang J, Wang KC, Chen Z, Chien S, Tsai MD, Shyy JY. PMID: 27965388; PMCID: PMC5206521.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    83. Flow-dependent YAP/TAZ activities regulate endothelial phenotypes and atherosclerosis. Proc Natl Acad Sci U S A. 2016 10 11; 113(41):11525-11530. Wang KC, Yeh YT, Nguyen P, Limqueco E, Lopez J, Thorossian S, Guan KL, Li YJ, Chien S. PMID: 27671657; PMCID: PMC5068257.
      View in: PubMed   Mentions: 251     Fields:    Translation:HumansAnimalsCells
    84. Moxifloxacin Improves Treatment Outcomes in Patients with Ofloxacin-Resistant Multidrug-Resistant Tuberculosis. Antimicrob Agents Chemother. 2016 08; 60(8):4708-16. Chien JY, Chien ST, Chiu WY, Yu CJ, Hsueh PR. PMID: 27216062; PMCID: PMC4958188.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    85. In-situ coupling between kinase activities and protein dynamics within single focal adhesions. Sci Rep. 2016 07 07; 6:29377. Wu Y, Zhang K, Seong J, Fan J, Chien S, Wang Y, Lu S. PMID: 27383747; PMCID: PMC4935953.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    86. Nuclear envelope proteins modulate proliferation of vascular smooth muscle cells during cyclic stretch application. Proc Natl Acad Sci U S A. 2016 May 10; 113(19):5293-8. Qi YX, Yao QP, Huang K, Shi Q, Zhang P, Wang GL, Han Y, Bao H, Wang L, Li HP, Shen BR, Wang Y, Chien S, Jiang ZL. PMID: 27114541; PMCID: PMC4868428.
      View in: PubMed   Mentions: 37     Fields:    Translation:AnimalsCells
    87. Mutations in gyrA and gyrB among Fluoroquinolone- and Multidrug-Resistant Mycobacterium tuberculosis Isolates. Antimicrob Agents Chemother. 2016 Apr; 60(4):2090-6. Chien JY, Chiu WY, Chien ST, Chiang CJ, Yu CJ, Hsueh PR. PMID: 26787695; PMCID: PMC4808166.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansCells
    88. Deterministically patterned biomimetic human iPSC-derived hepatic model via rapid 3D bioprinting. Proc Natl Acad Sci U S A. 2016 Feb 23; 113(8):2206-11. Ma X, Qu X, Zhu W, Li YS, Yuan S, Zhang H, Liu J, Wang P, Lai CS, Zanella F, Feng GS, Sheikh F, Chien S, Chen S. PMID: 26858399; PMCID: PMC4776497.
      View in: PubMed   Mentions: 329     Fields:    Translation:HumansCells
    89. Activation of integrin α5 mediated by flow requires its translocation to membrane lipid rafts in vascular endothelial cells. Proc Natl Acad Sci U S A. 2016 Jan 19; 113(3):769-74. Sun X, Fu Y, Gu M, Zhang L, Li D, Li H, Chien S, Shyy JY, Zhu Y. PMID: 26733684; PMCID: PMC4725528.
      View in: PubMed   Mentions: 64     Fields:    Translation:AnimalsCells
    90. Comparative Effectiveness of Angiotensin-Converting Enzyme Inhibitors and Angiotensin II Receptor Blockers in Terms of Major Cardiovascular Disease Outcomes in Elderly Patients: A Nationwide Population-Based Cohort Study. Medicine (Baltimore). 2015 Oct; 94(43):e1751. Chien SC, Ou SM, Shih CJ, Chao PW, Li SY, Lee YJ, Kuo SC, Wang SJ, Chen TJ, Tarng DC, Chu H, Chen YT. PMID: 26512568; PMCID: PMC4985382.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    91. Nanoparticle biointerfacing by platelet membrane cloaking. Nature. 2015 Oct 01; 526(7571):118-21. Hu CM, Fang RH, Wang KC, Luk BT, Thamphiwatana S, Dehaini D, Nguyen P, Angsantikul P, Wen CH, Kroll AV, Carpenter C, Ramesh M, Qu V, Patel SH, Zhu J, Shi W, Hofman FM, Chen TC, Gao W, Zhang K, Chien S, Zhang L. PMID: 26374997; PMCID: PMC4871317.
      View in: PubMed   Mentions: 606     Fields:    Translation:HumansAnimalsCells
    92. Bioinformatic analyses revealed underlying biological functions correlated with oxaliplatin responsiveness. Tumour Biol. 2016 Jan; 37(1):583-90. Klahan S, Huang CC, Chien SC, Wu MS, Wong HS, Huang CY, Chang WC, Wei PL. PMID: 26232912.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    93. Engineering as a new frontier for translational medicine. Sci Transl Med. 2015 Apr 01; 7(281):281fs13. Chien S, Bashir R, Nerem RM, Pettigrew R. PMID: 25834106; PMCID: PMC4698163.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    94. The influence of diabetes, glycemic control, and diabetes-related comorbidities on pulmonary tuberculosis. PLoS One. 2015; 10(3):e0121698. Chiang CY, Bai KJ, Lin HH, Chien ST, Lee JJ, Enarson DA, Lee TI, Yu MC. PMID: 25822974; PMCID: PMC4378948.
      View in: PubMed   Mentions: 73     Fields:    Translation:Humans
    95. Identification of AMP-activated protein kinase targets by a consensus sequence search of the proteome. BMC Syst Biol. 2015 Mar 11; 9:13. Marin TL, Gongol B, Martin M, King SJ, Smith L, Johnson DA, Subramaniam S, Chien S, Shyy JY. PMID: 25890336; PMCID: PMC4357066.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    96. Endothelial trauma from mechanical thrombectomy in acute stroke: in vitro live-cell platform with animal validation. Stroke. 2015 Apr; 46(4):1099-106. Teng D, Pannell JS, Rennert RC, Li J, Li YS, Wong VW, Chien S, Khalessi AA. PMID: 25712942.
      View in: PubMed   Mentions: 55     Fields:    Translation:Animals
    97. Outcome correlation of smear-positivity but culture-negativity during standard anti-tuberculosis treatment in Taiwan. BMC Infect Dis. 2015 Feb 18; 15:67. Chao WC, Huang YW, Yu MC, Yang WT, Lin CJ, Lee JJ, Huang RM, Shieh CC, Chien ST, Chien JY. PMID: 25886042; PMCID: PMC4339296.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    98. MicroRNA mediation of endothelial inflammatory response to smooth muscle cells and its inhibition by atheroprotective shear stress. Circ Res. 2015 Mar 27; 116(7):1157-69. Chen LJ, Chuang L, Huang YH, Zhou J, Lim SH, Lee CI, Lin WW, Lin TE, Wang WL, Chen L, Chien S, Chiu JJ. PMID: 25623956; PMCID: PMC4380766.
      View in: PubMed   Mentions: 37     Fields:    Translation:AnimalsCells
    99. Laudatio for Harry Goldsmith. Biorheology. 2015; 52(5-6):295-9. Chien S. PMID: 26639361.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    100. Oxidative stress activates endothelial innate immunity via sterol regulatory element binding protein 2 (SREBP2) transactivation of microRNA-92a. Circulation. 2015 Mar 03; 131(9):805-14. Chen Z, Wen L, Martin M, Hsu CY, Fang L, Lin FM, Lin TY, Geary MJ, Geary GG, Zhao Y, Johnson DA, Chen JW, Lin SJ, Chien S, Huang HD, Miller YI, Huang PH, Shyy JY. PMID: 25550450; PMCID: PMC4351177.
      View in: PubMed   Mentions: 88     Fields:    Translation:HumansAnimalsCells
    101. Osteoporosis increases subsequent risk of gallstone: a nationwide population-based cohort study in Taiwan. BMC Gastroenterol. 2014 Nov 18; 14:192. Klahan S, Kuo CN, Chien SC, Lin YW, Lin CY, Lin CH, Chang WC, Lin CI, Hung KS, Chang WP. PMID: 25404001; PMCID: PMC4247648.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    102. Intravenous immunoglobulin, pharmacogenomics, and Kawasaki disease. J Microbiol Immunol Infect. 2016 Feb; 49(1):1-7. Kuo HC, Hsu YW, Wu MS, Chien SC, Liu SF, Chang WC. PMID: 25556045.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    103. Genetic variants of CD209 associated with Kawasaki disease susceptibility. PLoS One. 2014; 9(8):e105236. Kuo HC, Huang YH, Chien SC, Yu HR, Hsieh KS, Hsu YW, Chang WC. PMID: 25148534; PMCID: PMC4141786.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    104. FAK and paxillin dynamics at focal adhesions in the protrusions of migrating cells. Sci Rep. 2014 Aug 12; 4:6024. Hu YL, Lu S, Szeto KW, Sun J, Wang Y, Lasheras JC, Chien S. PMID: 25113375; PMCID: PMC4129417.
      View in: PubMed   Mentions: 110     Fields:    Translation:AnimalsCells
    105. Decipher the dynamic coordination between enzymatic activity and structural modulation at focal adhesions in living cells. Sci Rep. 2014 Jul 24; 4:5756. Lu S, Seong J, Wang Y, Chang SC, Eichorst JP, Ouyang M, Li JY, Chien S, Wang Y. PMID: 25056908; PMCID: PMC4108961.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    106. Cation type specific cell remodeling regulates attachment strength. PLoS One. 2014; 9(7):e102424. Fuhrmann A, Li J, Chien S, Engler AJ. PMID: 25014042; PMCID: PMC4094514.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    107. Piezo1, a mechanically activated ion channel, is required for vascular development in mice. Proc Natl Acad Sci U S A. 2014 Jul 15; 111(28):10347-52. Ranade SS, Qiu Z, Woo SH, Hur SS, Murthy SE, Cahalan SM, Xu J, Mathur J, Bandell M, Coste B, Li YS, Chien S, Patapoutian A. PMID: 24958852; PMCID: PMC4104881.
      View in: PubMed   Mentions: 446     Fields:    Translation:AnimalsCells
    108. A Chinese herbal medicine, jia-wei-xiao-yao-san, prevents dimethylnitrosamine-induced hepatic fibrosis in rats. ScientificWorldJournal. 2014; 2014:217525. Chien SC, Chang WC, Lin PH, Chang WP, Hsu SC, Chang JC, Wu YC, Pei JK, Lin CH. PMID: 24995353; PMCID: PMC4065731.
      View in: PubMed   Mentions: 14     Fields:    Translation:Animals
    109. Epigenetic Mechanism in Regulation of Endothelial Function by Disturbed Flow: Induction of DNA Hypermethylation by DNMT1. Cell Mol Bioeng. 2014 Jun 01; 7(2):218-224. Zhou J, Li YS, Wang KC, Chien S. PMID: 24883126; PMCID: PMC4036703.
      View in: PubMed   Mentions: 56  
    110. Shear stress-initiated signaling and its regulation of endothelial function. Arterioscler Thromb Vasc Biol. 2014 Oct; 34(10):2191-8. Zhou J, Li YS, Chien S. PMID: 24876354; PMCID: PMC4169328.
      View in: PubMed   Mentions: 297     Fields:    Translation:HumansAnimalsCells
    111. MicroRNA-23b regulates cyclin-dependent kinase-activating kinase complex through cyclin H repression to modulate endothelial transcription and growth under flow. Arterioscler Thromb Vasc Biol. 2014 Jul; 34(7):1437-45. Wang KC, Nguyen P, Weiss A, Yeh YT, Chien HS, Lee A, Teng D, Subramaniam S, Li YS, Chien S. PMID: 24855060; PMCID: PMC4119726.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    112. Glycemic control and radiographic manifestations of tuberculosis in diabetic patients. PLoS One. 2014; 9(4):e93397. Chiang CY, Lee JJ, Chien ST, Enarson DA, Chang YC, Chen YT, Hu TY, Lin CB, Suk CW, Tao JM, Bai KJ. PMID: 24699457; PMCID: PMC3974751.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansPHPublic Health
    113. Genetic polymorphisms of ORAI1 and chronic kidney disease in Taiwanese population. Biomed Res Int. 2014; 2014:290863. Hwang DY, Chien SC, Hsu YW, Kao CC, Cheng SY, Lu HC, Wu MS, Chang JM. PMID: 24745010; PMCID: PMC3976823.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    114. Single-nucleotide polymorphism rs7251246 in ITPKC is associated with susceptibility and coronary artery lesions in Kawasaki disease. PLoS One. 2014; 9(3):e91118. Kuo HC, Hsu YW, Lo MH, Huang YH, Chien SC, Chang WC. PMID: 24621571; PMCID: PMC3951297.
      View in: PubMed   Mentions: 26     Fields:    Translation:Humans
    115. Adjunctive traditional Chinese medicine therapy improves survival in patients with advanced breast cancer: a population-based study. Cancer. 2014 May 01; 120(9):1338-44. Lee YW, Chen TL, Shih YR, Tsai CL, Chang CC, Liang HH, Tseng SH, Chien SC, Wang CC. PMID: 24496917.
      View in: PubMed   Mentions: 62     Fields:    Translation:Humans
    116. Calcium phosphate-bearing matrices induce osteogenic differentiation of stem cells through adenosine signaling. Proc Natl Acad Sci U S A. 2014 Jan 21; 111(3):990-5. Shih YR, Hwang Y, Phadke A, Kang H, Hwang NS, Caro EJ, Nguyen S, Siu M, Theodorakis EA, Gianneschi NC, Vecchio KS, Chien S, Lee OK, Varghese S. PMID: 24395775; PMCID: PMC3903237.
      View in: PubMed   Mentions: 130     Fields:    Translation:HumansCells
    117. Relative impact of uniaxial alignment vs. form-induced stress on differentiation of human adipose derived stem cells. Biomaterials. 2013 Dec; 34(38):9812-8. Qu X, Zhu W, Huang S, Li JY, Chien S, Zhang K, Chen S. PMID: 24060419; PMCID: PMC3830579.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    118. Regulation of vascular smooth muscle cell turnover by endothelial cell-secreted microRNA-126: role of shear stress. Circ Res. 2013 Jun 21; 113(1):40-51. Zhou J, Li YS, Nguyen P, Wang KC, Weiss A, Kuo YC, Chiu JJ, Shyy JY, Chien S. PMID: 23603512; PMCID: PMC3772783.
      View in: PubMed   Mentions: 133     Fields:    Translation:HumansAnimalsCells
    119. Matrix stiffness regulates endothelial cell proliferation through septin 9. PLoS One. 2012; 7(10):e46889. Yeh YT, Hur SS, Chang J, Wang KC, Chiu JJ, Li YS, Chien S. PMID: 23118862; PMCID: PMC3485289.
      View in: PubMed   Mentions: 80     Fields:    Translation:HumansCells
    120. Infection of vascular endothelial cells with human cytomegalovirus under fluid shear stress reveals preferential entry and spread of virus in flow conditions simulating atheroprone regions of the artery. J Virol. 2012 Dec; 86(24):13745-55. DuRose JB, Li J, Chien S, Spector DH. PMID: 23055562; PMCID: PMC3503096.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    121. UCSD's Institute of Engineering in Medicine: fostering collaboration through research and education. IEEE Pulse. 2012 Jul; 3(4):35-41. Chien S. PMID: 22850836.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    122. Roles of cell confluency and fluid shear in 3-dimensional intracellular forces in endothelial cells. Proc Natl Acad Sci U S A. 2012 Jul 10; 109(28):11110-5. Hur SS, del Álamo JC, Park JS, Li YS, Nguyen HA, Teng D, Wang KC, Flores L, Alonso-Latorre B, Lasheras JC, Chien S. PMID: 22665785; PMCID: PMC3396533.
      View in: PubMed   Mentions: 62     Fields:    Translation:HumansAnimalsCells
    123. Arrayed cellular microenvironments for identifying culture and differentiation conditions for stem, primary and rare cell populations. Nat Protoc. 2012 Mar 15; 7(4):703-17. Brafman DA, Chien S, Willert K. PMID: 22422316.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    124. Proteolytic Activity Attenuates the Response of Endothelial Cells to Fluid Shear Stress. Cell Mol Bioeng. 2012 Mar; 5(1):82-91. Altshuler AE, Morgan MJ, Chien S, Schmid-Schönbein GW. PMID: 22545072; PMCID: PMC3337682.
      View in: PubMed   Mentions: 5  
    125. MicroRNA-21 targets peroxisome proliferators-activated receptor-alpha in an autoregulatory loop to modulate flow-induced endothelial inflammation. Proc Natl Acad Sci U S A. 2011 Jun 21; 108(25):10355-60. Zhou J, Wang KC, Wu W, Subramaniam S, Shyy JY, Chiu JJ, Li JY, Chien S. PMID: 21636785; PMCID: PMC3121870.
      View in: PubMed   Mentions: 178     Fields:    Translation:HumansCells
    126. A brief history of the Bioengineering Institute of California and the UC System-wide Symposia. Ann Biomed Eng. 2011 Apr; 39(4):1156-62. Chien S. PMID: 21384235; PMCID: PMC3069316.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    127. Long-term human pluripotent stem cell self-renewal on synthetic polymer surfaces. Biomaterials. 2010 Dec; 31(34):9135-44. Brafman DA, Chang CW, Fernandez A, Willert K, Varghese S, Chien S. PMID: 20817292; PMCID: PMC2949524.
      View in: PubMed   Mentions: 64     Fields:    Translation:HumansCells
    128. ViewDock TDW: high-throughput visualization of virtual screening results. Bioinformatics. 2010 Aug 01; 26(15):1915-7. Lau CD, Levesque MJ, Chien S, Date S, Haga JH. PMID: 20551133; PMCID: PMC2905552.
      View in: PubMed   Mentions: 1     Fields:    
    129. Role of microRNA-23b in flow-regulation of Rb phosphorylation and endothelial cell growth. Proc Natl Acad Sci U S A. 2010 Feb 16; 107(7):3234-9. Wang KC, Garmire LX, Young A, Nguyen P, Trinh A, Subramaniam S, Wang N, Shyy JY, Li YS, Chien S. PMID: 20133741; PMCID: PMC2840325.
      View in: PubMed   Mentions: 97     Fields:    Translation:HumansCells
    130. Grid heterogeneity in in-silico experiments: an exploration of drug screening using DOCK on cloud environments. Stud Health Technol Inform. 2010; 159:181-90. Yim WW, Chien S, Kusumoto Y, Date S, Haga J. PMID: 20543437.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    131. Defining long-term maintenance conditions of human embryonic stem cells with arrayed cellular microenvironment technology. Stem Cells Dev. 2009 Oct; 18(8):1141-54. Brafman DA, Shah KD, Fellner T, Chien S, Willert K. PMID: 19327010.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansCells
    132. A Tribute to Professor Van C. Mow: A Wonderful Scholar and Leader in Bioengineering. Cell Mol Bioeng. 2009 Sep; 2(3):282-284. Chien S. PMID: 19779632; PMCID: PMC2749170.
      View in: PubMed   Mentions:
    133. Flow activation of AMP-activated protein kinase in vascular endothelium leads to Krüppel-like factor 2 expression. Arterioscler Thromb Vasc Biol. 2009 Nov; 29(11):1902-8. Young A, Wu W, Sun W, Benjamin Larman H, Larman HB, Wang N, Li YS, Shyy JY, Chien S, García-Cardeña G. PMID: 19696400; PMCID: PMC2766008.
      View in: PubMed   Mentions: 66     Fields:    Translation:HumansAnimalsCells
    134. Investigating the role of the extracellular environment in modulating hepatic stellate cell biology with arrayed combinatorial microenvironments. Integr Biol (Camb). 2009 Sep; 1(8-9):513-24. Brafman DA, de Minicis S, Seki E, Shah KD, Teng D, Brenner D, Willert K, Chien S. PMID: 20023766.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    135. Anisotropic rheology and directional mechanotransduction in vascular endothelial cells. Proc Natl Acad Sci U S A. 2008 Oct 07; 105(40):15411-6. del Alamo JC, Norwich GN, Li YS, Lasheras JC, Chien S. PMID: 18840694; PMCID: PMC2563098.
      View in: PubMed   Mentions: 39     Fields:    Translation:AnimalsCells
    136. Pulsatile equibiaxial stretch inhibits thrombin-induced RhoA and NF-kappaB activation. Biochem Biophys Res Commun. 2008 Jul 18; 372(1):216-20. Haga JH, Kaunas R, Radeff-Huang J, Weems JM, Estrada KD, Chien S, Brown JH, Seasholtz TM. PMID: 18474218; PMCID: PMC2587448.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    137. Role of shear stress direction in endothelial mechanotransduction. Mol Cell Biomech. 2008 Mar; 5(1):1-8. Chien S. PMID: 18524241.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    138. Combinatorial signaling microenvironments for studying stem cell fate. Stem Cells Dev. 2008 Feb; 17(1):29-39. Flaim CJ, Teng D, Chien S, Bhatia SN. PMID: 18271698.
      View in: PubMed   Mentions: 88     Fields:    Translation:HumansCells
    139. Effects of disturbed flow on endothelial cells. Ann Biomed Eng. 2008 Apr; 36(4):554-62. Chien S. PMID: 18172767; PMCID: PMC3718045.
      View in: PubMed   Mentions: 149     Fields:    Translation:HumansAnimalsCells
    140. mTOR is the rapamycin-sensitive kinase that confers mechanically-induced phosphorylation of the hydrophobic motif site Thr(389) in p70(S6k). FEBS Lett. 2007 Oct 02; 581(24):4562-6. Hornberger TA, Sukhija KB, Wang XR, Chien S. PMID: 17825298; PMCID: PMC2084087.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    141. Selective adapter recruitment and differential signaling networks by VEGF vs. shear stress. Proc Natl Acad Sci U S A. 2007 May 22; 104(21):8875-9. Wang Y, Chang J, Chen KD, Li S, Li JY, Wu C, Chien S. PMID: 17496149; PMCID: PMC1885595.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    142. In vivo knee moments and shear after total knee arthroplasty. J Biomech. 2007; 40 Suppl 1:S11-7. D'Lima DD, Patil S, Steklov N, Chien S, Colwell CW. PMID: 17462659.
      View in: PubMed   Mentions: 62     Fields:    Translation:Humans
    143. Dynamic motion of paxillin on actin filaments in living endothelial cells. Biochem Biophys Res Commun. 2007 Jun 15; 357(4):871-6. Hu YL, Chien S. PMID: 17466945; PMCID: PMC2025639.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    144. Directional shear flow and Rho activation prevent the endothelial cell apoptosis induced by micropatterned anisotropic geometry. Proc Natl Acad Sci U S A. 2007 Jan 23; 104(4):1254-9. Wu CC, Li YS, Haga JH, Kaunas R, Chiu JJ, Su FC, Usami S, Chien S. PMID: 17229844; PMCID: PMC1783086.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansCells
    145. Mechanotransduction and endothelial cell homeostasis: the wisdom of the cell. Am J Physiol Heart Circ Physiol. 2007 Mar; 292(3):H1209-24. Chien S. PMID: 17098825.
      View in: PubMed   Mentions: 355     Fields:    Translation:HumansAnimalsCells
    146. Roles of microfilaments and microtubules in paxillin dynamics. Biochem Biophys Res Commun. 2006 Oct 06; 348(4):1463-71. Hu YL, Haga JH, Miao H, Wang Y, Li YS, Chien S. PMID: 16920067.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    147. Molecular basis of the effects of mechanical stretch on vascular smooth muscle cells. J Biomech. 2007; 40(5):947-60. Haga JH, Li YS, Chien S. PMID: 16867303.
      View in: PubMed   Mentions: 134     Fields:    Translation:HumansAnimalsCells
    148. Regulation of mTOR by mechanically induced signaling events in skeletal muscle. Cell Cycle. 2006 Jul; 5(13):1391-6. Hornberger TA, Sukhija KB, Chien S. PMID: 16855395.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    149. Mechanical stimuli and nutrients regulate rapamycin-sensitive signaling through distinct mechanisms in skeletal muscle. J Cell Biochem. 2006 Apr 15; 97(6):1207-16. Hornberger TA, Chien S. PMID: 16315321.
      View in: PubMed   Mentions: 45     Fields:    Translation:AnimalsCells
    150. Integrins regulate VE-cadherin and catenins: dependence of this regulation on Src, but not on Ras. Proc Natl Acad Sci U S A. 2006 Feb 07; 103(6):1774-9. Wang Y, Jin G, Miao H, Li JY, Usami S, Chien S. PMID: 16446427; PMCID: PMC1413667.
      View in: PubMed   Mentions: 52     Fields:    Translation:AnimalsCells
    151. Shear stress regulation of Krüppel-like factor 2 expression is flow pattern-specific. Biochem Biophys Res Commun. 2006 Mar 24; 341(4):1244-51. Wang N, Miao H, Li YS, Zhang P, Haga JH, Hu Y, Young A, Yuan S, Nguyen P, Wu CC, Chien S. PMID: 16466697.
      View in: PubMed   Mentions: 72     Fields:    Translation:HumansAnimalsCells
    152. Chronotropic response of cultured neonatal rat ventricular myocytes to short-term fluid shear. Cell Biochem Biophys. 2006; 46(2):113-22. Lorenzen-Schmidt I, Schmid-Schönbein GW, Giles WR, McCulloch AD, Chien S, Omens JH. PMID: 17012753; PMCID: PMC3310206.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    153. Molecular basis of rheological modulation of endothelial functions: importance of stress direction. Biorheology. 2006; 43(2):95-116. Chien S. PMID: 16687781.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    154. Cooperative effects of Rho and mechanical stretch on stress fiber organization. Proc Natl Acad Sci U S A. 2005 Nov 01; 102(44):15895-900. Kaunas R, Nguyen P, Usami S, Chien S. PMID: 16247009; PMCID: PMC1276069.
      View in: PubMed   Mentions: 179     Fields:    Translation:AnimalsCells
    155. Molecular basis of the effects of shear stress on vascular endothelial cells. J Biomech. 2005 Oct; 38(10):1949-71. Li YS, Haga JH, Chien S. PMID: 16084198.
      View in: PubMed   Mentions: 348     Fields:    Translation:HumansCells
    156. Molecular basis of mechanical modulation of endothelial cell migration. Front Biosci. 2005 May 01; 10:1985-2000. Chien S, Li S, Shiu YT, Li YS. PMID: 15769679.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    157. An extracellular matrix microarray for probing cellular differentiation. Nat Methods. 2005 Feb; 2(2):119-25. Flaim CJ, Chien S, Bhatia SN. PMID: 15782209.
      View in: PubMed   Mentions: 277     Fields:    Translation:AnimalsCells
    158. Effects of flow patterns on the localization and expression of VE-cadherin at vascular endothelial cell junctions: in vivo and in vitro investigations. J Vasc Res. 2005 Jan-Feb; 42(1):77-89. Miao H, Hu YL, Shiu YT, Yuan S, Zhao Y, Kaunas R, Wang Y, Jin G, Usami S, Chien S. PMID: 15637443.
      View in: PubMed   Mentions: 80     Fields:    Translation:AnimalsCells
    159. Control of neutrophil pseudopods by fluid shear: role of Rho family GTPases. Am J Physiol Cell Physiol. 2005 Apr; 288(4):C863-71. Makino A, Glogauer M, Bokoch GM, Chien S, Schmid-Schönbein GW. PMID: 15561759.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    160. Rho mediates the shear-enhancement of endothelial cell migration and traction force generation. Biophys J. 2004 Apr; 86(4):2558-65. Shiu YT, Li S, Marganski WA, Usami S, Schwartz MA, Wang YL, Dembo M, Chien S. PMID: 15041692; PMCID: PMC1304103.
      View in: PubMed   Mentions: 63     Fields:    Translation:AnimalsCells
    161. The National Institute of Biomedical Imaging and Bioengineering. Annu Rev Biomed Eng. 2004; 6:1-26. Chien S. PMID: 15255760.
      View in: PubMed   Mentions: 1     Fields:    
    162. Shear stress and VEGF activate IKK via the Flk-1/Cbl/Akt signaling pathway. Am J Physiol Heart Circ Physiol. 2004 Feb; 286(2):H685-92. Wang Y, Chang J, Li YC, Li YS, Shyy JY, Chien S. PMID: 14551058.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    163. Molecular and mechanical bases of focal lipid accumulation in arterial wall. Prog Biophys Mol Biol. 2003 Oct; 83(2):131-51. Chien S. PMID: 12865076.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansAnimalsCells
    164. Shear stress-induced c-fos activation is mediated by Rho in a calcium-dependent manner. Biochem Biophys Res Commun. 2003 Apr 04; 303(2):548-55. Shiu YT, Li S, Yuan S, Wang Y, Nguyen P, Chien S. PMID: 12659853.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    165. The influence of hyperbaric oxygen on hemorheological parameters in diabetic rats. Biorheology. 2003; 40(6):605-12. Liu DZ, Chien SC, Tseng LP, Yang CB. PMID: 14610311.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    166. Improved significance test for DNA microarray data: temporal effects of shear stress on endothelial genes. Physiol Genomics. 2002 Dec 26; 12(1):1-11. Zhao Y, Chen BP, Miao H, Yuan S, Li YS, Hu Y, Rocke DM, Chien S. PMID: 12399447.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    167. Genomic analysis of smooth muscle cells in 3-dimensional collagen matrix. FASEB J. 2003 Jan; 17(1):97-9. Li S, Lao J, Chen BP, Li YS, Zhao Y, Chu J, Chen KD, Tsou TC, Peck K, Chien S. PMID: 12475912.
      View in: PubMed   Mentions: 51     Fields:    Translation:HumansCells
    168. Roles of microtubule dynamics and small GTPase Rac in endothelial cell migration and lamellipodium formation under flow. J Vasc Res. 2002 Nov-Dec; 39(6):465-76. Hu YL, Li S, Miao H, Tsou TC, del Pozo MA, Chien S. PMID: 12566972.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    169. Interplay between integrins and FLK-1 in shear stress-induced signaling. Am J Physiol Cell Physiol. 2002 Nov; 283(5):C1540-7. Wang Y, Miao H, Li S, Chen KD, Li YS, Yuan S, Shyy JY, Chien S. PMID: 12372815.
      View in: PubMed   Mentions: 42     Fields:    Translation:AnimalsCells
    170. Differential regulation of Rho GTPases by beta1 and beta3 integrins: the role of an extracellular domain of integrin in intracellular signaling. J Cell Sci. 2002 May 15; 115(Pt 10):2199-206. Miao H, Li S, Hu YL, Yuan S, Zhao Y, Chen BP, Puzon-McLaughlin W, Tarui T, Shyy JY, Takada Y, Usami S, Chien S. PMID: 11973360.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansAnimalsCells
    171. Role of Cbl in shear-activation of PI 3-kinase and JNK in endothelial cells. Biochem Biophys Res Commun. 2002 Apr 12; 292(4):892-9. Miao H, Yuan S, Wang Y, Tsygankov A, Chien S. PMID: 11944898.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    172. The role of the dynamics of focal adhesion kinase in the mechanotaxis of endothelial cells. Proc Natl Acad Sci U S A. 2002 Mar 19; 99(6):3546-51. Li S, Butler P, Wang Y, Hu Y, Han DC, Usami S, Guan JL, Chien S. PMID: 11891289; PMCID: PMC122560.
      View in: PubMed   Mentions: 94     Fields:    Translation:AnimalsCells
    173. Shear stress activation of SREBP1 in endothelial cells is mediated by integrins. Arterioscler Thromb Vasc Biol. 2002 Jan; 22(1):76-81. Liu Y, Chen BP, Lu M, Zhu Y, Stemerman MB, Chien S, Shyy JY. PMID: 11788464.
      View in: PubMed   Mentions: 58     Fields:    Translation:AnimalsCells
    174. Rate sensitivity of shear-induced changes in the lateral diffusion of endothelial cell membrane lipids: a role for membrane perturbation in shear-induced MAPK activation. FASEB J. 2002 Feb; 16(2):216-8. Butler PJ, Tsou TC, Li JY, Usami S, Chien S. PMID: 11744620.
      View in: PubMed   Mentions: 32     Fields:    Translation:Cells
    Shu's Networks
    Concepts (780)
    Derived automatically from this person's publications.
    Explore
    _
    Co-Authors (50)
    People in Profiles who have published with this person.
    Explore
    _
    Similar People (60)
    People who share similar concepts with this person.
    Explore
    _
    Same Department
    Search Department
    _

    UCSD Profiles is managed by the UC San Diego Altman Clinical and Translational Research Institute (ACTRI).
    This site is running Profiles RNS version UCSF-v3.1.0-16-gff1bd585 on PROFILES-PWEB04. We use cookies to operate our website. We also use cookies to analyze our site’s performance and improve your experience on our site. For more information about how we use cookies, please see our Website Terms of Use.

    Copyright © The Regents of the University of California