Shu Chien

Title(s)Emeritus Professor, Bioengineering
SchoolVc-academic Affairs
Address9500 Gilman Drive #
La Jolla CA 92093
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    Collapse Research 
    Collapse Research Activities and Funding
    Locus-specific Imaging of Dynamic Histone Methylations during Reprogramming
    NIH R01GM125379Aug 3, 2017 - Apr 30, 2021
    Role: Co-Principal Investigator
    The second phase of NIH Common Fund 4D Nucleome Network Organizational Hub
    NIH U01CA200147Sep 1, 2015 - Aug 31, 2025
    Role: Principal Investigator
    Role of Spatiotemporal Epigenetic Dynamics in Regulating Endothelial Gene Expressions under Flows
    NIH R01HL121365Dec 20, 2013 - Nov 30, 2021
    Role: Principal Investigator
    Systems Biology Analyses for Hemodynamic Regulation of Vascular Homeostasis
    NIH R01HL108735Aug 24, 2012 - Jul 31, 2025
    Role: Principal Investigator
    Nucleolin Regulation of miRome by Shear Stress
    NIH R01HL106579Jan 1, 2011 - Nov 30, 2022
    Role: Principal Investigator
    Integrative Bioengineering of Heart, Vessels, and Blood
    NIH T32HL105373Sep 20, 2010 - Aug 31, 2021
    Role: Principal Investigator
    Optimization of the Chemical-Physical Environments for Stem Cell Differentiation
    NIH R21HL104402Jul 1, 2010 - Jun 30, 2012
    Role: Principal Investigator
    UCSD MARC Program
    NIH T34GM087193Jun 1, 2009 - May 31, 2015
    Role: Principal Investigator
    Confocal Laser Scanning Biological Microscope Olympus Fv1000
    NIH S10RR025630Apr 1, 2009 - Mar 31, 2010
    Role: Principal Investigator
    The Role of Phosphatases in EC Mechanotransduction
    NIH R01HL085159Jul 1, 2006 - Jun 30, 2011
    Role: Principal Investigator
    Mechanical Feedback on Cell Structure and Signaling
    NIH R01HL080518Feb 1, 2006 - Jan 31, 2011
    Role: Principal Investigator
    NIH P42ES010337Jul 1, 2000 - Mar 31, 2022
    Role: Co-Investigator
    NIH R01HL062747Feb 8, 2000 - Jan 31, 2004
    Role: Principal Investigator
    Mechanical and Molecular Bases of Endothelial Remodeling
    NIH R01HL064382Sep 28, 1999 - Jul 31, 2011
    Role: Principal Investigator
    NIH R13HL058979Sep 1, 1997 - Aug 31, 1998
    Role: Principal Investigator
    Biomechanics of the Heart, Vessels, and Blood Cells
    NIH P01HL043026Jul 1, 1990 - May 31, 2007
    Role: Principal Investigator
    NIH R37HL044147May 1, 1989 - Apr 30, 2000
    Role: Principal Investigator
    NIH T32HL007114Jul 1, 1980 - Aug 31, 1990
    Role: Principal Investigator
    NIH P01HL016851Jun 1, 1979 - May 31, 1990
    Role: Principal Investigator
    Molecular Mechanism of Endothelial Migration Under Flow
    NIH R01HL019454Dec 1, 1976 - Jun 30, 2006
    Role: Principal Investigator
    Cardiovascular Engineering Science
    NIH T32HL007089Jul 1, 1975 - Oct 3, 2012
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Dr. Y. C. Fung's Contributions to Biomechanics, Bioengineering, and Humanity: Warmest Celebration for a Magnificent Centenarian. J Biomech Eng. 2019 Sep 01; 141(9). Chien S. PMID: 31215621.
      View in: PubMed   Mentions: 1     Fields:    
    2. Engineering as a new frontier for translational medicine. Sci Transl Med. 2015 Apr 01; 7(281):281fs13. Chien S, Bashir R, Nerem RM, Pettigrew R. PMID: 25834106; PMCID: PMC4698163.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    3. Shear stress-initiated signaling and its regulation of endothelial function. Arterioscler Thromb Vasc Biol. 2014 Oct; 34(10):2191-8. Zhou J, Li YS, Chien S. PMID: 24876354; PMCID: PMC4169328.
      View in: PubMed   Mentions: 222     Fields:    Translation:HumansAnimalsCells
    4. UCSD's Institute of Engineering in Medicine: fostering collaboration through research and education. IEEE Pulse. 2012 Jul; 3(4):35-41. Chien S. PMID: 22850836.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    5. A brief history of the Bioengineering Institute of California and the UC System-wide Symposia. Ann Biomed Eng. 2011 Apr; 39(4):1156-62. Chien S. PMID: 21384235; PMCID: PMC3069316.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    6. Effects of disturbed flow on endothelial cells. Ann Biomed Eng. 2008 Apr; 36(4):554-62. Chien S. PMID: 18172767; PMCID: PMC3718045.
      View in: PubMed   Mentions: 138     Fields:    Translation:HumansAnimalsCells
    7. Mechanotransduction and endothelial cell homeostasis: the wisdom of the cell. Am J Physiol Heart Circ Physiol. 2007 Mar; 292(3):H1209-24. Chien S. PMID: 17098825.
      View in: PubMed   Mentions: 320     Fields:    Translation:HumansAnimalsCells
    8. Molecular basis of rheological modulation of endothelial functions: importance of stress direction. Biorheology. 2006; 43(2):95-116. Chien S. PMID: 16687781.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    9. Molecular basis of mechanical modulation of endothelial cell migration. Front Biosci. 2005 May 01; 10:1985-2000. Chien S, Li S, Shiu YT, Li YS. PMID: 15769679.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    10. The National Institute of Biomedical Imaging and Bioengineering. Annu Rev Biomed Eng. 2004; 6:1-26. Chien S. PMID: 15255760.
      View in: PubMed   Mentions: 1     Fields: