Shu Chien

Title(s)	Emeritus Professor, Bioengineering
School	Vc-academic Affairs
Address	9500 Gilman Drive # La Jolla CA 92093
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Research

Research Activities and Funding

Locus-specific Imaging of Dynamic Histone Methylations during Reprogramming
NIH R01GM125379Aug 3, 2017 - Apr 30, 2021
Role: Co-Principal Investigator

The second phase of NIH Common Fund 4D Nucleome Network Organizational Hub
NIH U01CA200147Sep 1, 2015 - Aug 31, 2025
Role: Principal Investigator

Role of Spatiotemporal Epigenetic Dynamics in Regulating Endothelial Gene Expressions under Flows
NIH R01HL121365Dec 20, 2013 - Nov 30, 2021
Role: Principal Investigator

Systems Biology Analyses for Hemodynamic Regulation of Vascular Homeostasis
NIH R01HL108735Aug 24, 2012 - Jul 31, 2025
Role: Principal Investigator

Nucleolin Regulation of miRome by Shear Stress
NIH R01HL106579Jan 1, 2011 - Nov 30, 2022
Role: Principal Investigator

Integrative Bioengineering of Heart, Vessels, and Blood
NIH T32HL105373Sep 20, 2010 - Aug 31, 2021
Role: Principal Investigator

Optimization of the Chemical-Physical Environments for Stem Cell Differentiation
NIH R21HL104402Jul 1, 2010 - Jun 30, 2012
Role: Principal Investigator

UCSD MARC Program
NIH T34GM087193Jun 1, 2009 - May 31, 2015
Role: Principal Investigator

Confocal Laser Scanning Biological Microscope Olympus Fv1000
NIH S10RR025630Apr 1, 2009 - Mar 31, 2010
Role: Principal Investigator

The Role of Phosphatases in EC Mechanotransduction
NIH R01HL085159Jul 1, 2006 - Jun 30, 2011
Role: Principal Investigator

Mechanical Feedback on Cell Structure and Signaling
NIH R01HL080518Feb 1, 2006 - Jan 31, 2011
Role: Principal Investigator

DETECTION AND MODELS OF TOXICANT EXPOSURE
NIH P42ES010337Jul 1, 2000 - Mar 31, 2022
Role: Co-Investigator

MECHANISMS OF REPERFUSION INDUCTION OF ROS AND IKK
NIH R01HL062747Feb 8, 2000 - Jan 31, 2004
Role: Principal Investigator

Mechanical and Molecular Bases of Endothelial Remodeling
NIH R01HL064382Sep 28, 1999 - Jul 31, 2011
Role: Principal Investigator

1997 BIOMEDICAL ENGINEERING SOCIETY FALL MEETING
NIH R13HL058979Sep 1, 1997 - Aug 31, 1998
Role: Principal Investigator

Biomechanics of the Heart, Vessels, and Blood Cells
NIH P01HL043026Jul 1, 1990 - May 31, 2007
Role: Principal Investigator

BLOOD CELL PROPERTIES AND CIRCULATORY REGULATION
NIH R37HL044147May 1, 1989 - Apr 30, 2000
Role: Principal Investigator

RHEOLOGY IN CARDIOVASCULAR DISEASES
NIH T32HL007114Jul 1, 1980 - Aug 31, 1990
Role: Principal Investigator

HUMAN BLOOD CELL MEMBRANES IN HEALTH AND DISEASE
NIH P01HL016851Jun 1, 1979 - May 31, 1990
Role: Principal Investigator

Molecular Mechanism of Endothelial Migration Under Flow
NIH R01HL019454Dec 1, 1976 - Jun 30, 2006
Role: Principal Investigator

Cardiovascular Engineering Science
NIH T32HL007089Jul 1, 1975 - Oct 3, 2012
Role: Principal Investigator

Bibliographic

Publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.

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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.

Dr. Y. C. Fung's Contributions to Biomechanics, Bioengineering, and Humanity: Warmest Celebration for a Magnificent Centenarian. J Biomech Eng. 2019 Sep 01; 141(9). Chien S. PMID: 31215621.

View in: PubMed Mentions: 1 Fields:
Bio Biomedical Engineering
Engineering as a new frontier for translational medicine. Sci Transl Med. 2015 Apr 01; 7(281):281fs13. Chien S, Bashir R, Nerem RM, Pettigrew R. PMID: 25834106; PMCID: PMC4698163.

View in: PubMed Mentions: 7 Fields:
Med Medicine (General)Sci Science
Translation:Humans
Shear stress-initiated signaling and its regulation of endothelial function. Arterioscler Thromb Vasc Biol. 2014 Oct; 34(10):2191-8. Zhou J, Li YS, Chien S. PMID: 24876354; PMCID: PMC4169328.

View in: PubMed Mentions: 239 Fields:
Vas Vascular Diseases
Translation:Humans Animals Cells
UCSD's Institute of Engineering in Medicine: fostering collaboration through research and education. IEEE Pulse. 2012 Jul; 3(4):35-41. Chien S. PMID: 22850836.

View in: PubMed Mentions: Fields:
Bio Biomedical Engineering
Translation:Humans
A brief history of the Bioengineering Institute of California and the UC System-wide Symposia. Ann Biomed Eng. 2011 Apr; 39(4):1156-62. Chien S. PMID: 21384235; PMCID: PMC3069316.

View in: PubMed Mentions: Fields:
Bio Biomedical Engineering
Translation:Humans
Effects of disturbed flow on endothelial cells. Ann Biomed Eng. 2008 Apr; 36(4):554-62. Chien S. PMID: 18172767; PMCID: PMC3718045.

View in: PubMed Mentions: 135 Fields:
Bio Biomedical Engineering
Translation:Humans Animals Cells
Mechanotransduction and endothelial cell homeostasis: the wisdom of the cell. Am J Physiol Heart Circ Physiol. 2007 Mar; 292(3):H1209-24. Chien S. PMID: 17098825.

View in: PubMed Mentions: 319 Fields:
Car Cardiology Phy Physiology
Translation:Humans Animals Cells
Molecular basis of rheological modulation of endothelial functions: importance of stress direction. Biorheology. 2006; 43(2):95-116. Chien S. PMID: 16687781.

View in: PubMed Mentions: 11 Fields:
Bio Biophysics Phy Physiology
Translation:Humans Cells
Molecular basis of mechanical modulation of endothelial cell migration. Front Biosci. 2005 May 01; 10:1985-2000. Chien S, Li S, Shiu YT, Li YS. PMID: 15769679.

View in: PubMed Mentions: 21 Fields:
Bio Biology
Translation:Humans Animals Cells
The National Institute of Biomedical Imaging and Bioengineering. Annu Rev Biomed Eng. 2004; 6:1-26. Chien S. PMID: 15255760.

View in: PubMed Mentions: 1 Fields:
Bio Biomedical Engineering