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Frederick Han

Title(s)Associate Clinical Professor, Medicine
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    1. Pericardial Effusion Requiring Intervention in Patients Undergoing Percutaneous Left Atrial Appendage Occlusion: Prevalence, Predictors and Associated In-hospital Adverse Events from 17,700 Procedures in the United States. Heart Rhythm. 2021 May 18. Munir MB, Khan MZ, Darden D, Pasupula DK, Balla S, Han FT, Reeves R, Hsu JC. PMID: 34020049.
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    2. Racial Disparities in In-hospital Adverse Events Among Patients with Atrial Fibrillation Implanted with a Watchman Left Atrial Appendage Occlusion Device: A United States National Perspective. Circ Arrhythm Electrophysiol. 2021 Apr 28. Khan MZ, Munir MB, Darden D, Pasupula DK, Balla S, Han FT, Reeves R, Hsu JC. PMID: 33909473.
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    3. Association between early recurrences of atrial tachyarrhythmias and long-term outcomes in patients after repeat atrial fibrillation ablation. J Interv Card Electrophysiol. 2021 Apr 07. Darden D, Aldaas O, Malladi CL, Mylavarapu PS, Munir MB, Han FT, Hoffmayer KS, Raissi F, Ho G, Krummen D, Feld GK, Hsu JC. PMID: 33826085.
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    4. Electrical Substrate Ablation for Refractory Ventricular Fibrillation: Results of the AVATAR Study. Circ Arrhythm Electrophysiol. 2021 Feb 07. Krummen DE, Ho G, Hoffmayer KS, Schweis F, Baykaner T, Rogers AJ, Han FT, Hsu JC, Viswanathan MN, Wang PJ, Rappel WJ, Narayan SM. PMID: 33550811.
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    5. Ablation of mitral annular flutter ablation utilizing a left atrial anterior line versus a lateral mitral isthmus line: a systematic review and meta-analysis. J Interv Card Electrophysiol. 2021 Feb 04. Aldaas OM, Lupercio F, Lin AY, Han FT, Hoffmayer KS, Raissi F, Ho G, Krummen D, Feld GK, Hsu JC. PMID: 33538952.
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    6. Successful use of a prophylactic cerebral protection device via the radial artery during left atrial appendage occlusion device implantation in a patient with a mitral valve mass. HeartRhythm Case Rep. 2021 Apr; 7(4):242-245. Shah K, Reeves RR, Narezkina A, Castellanos LR, Han FT, Hsu JC. PMID: 34026505.
      View in: PubMed   Mentions:
    7. Meta-analysis of the Usefulness of Catheter Ablation of Atrial Fibrillation in Patients With Heart Failure With Preserved Ejection Fraction. Am J Cardiol. 2021 Mar 01; 142:66-73. Aldaas OM, Lupercio F, Darden D, Mylavarapu PS, Malladi CL, Han FT, Hoffmayer KS, Krummen D, Ho G, Raissi F, Birgersdotter-Green U, Feld GK, Hsu JC. PMID: 33290688.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    8. Recurrent syncope resulting from large carotid atheroma. HeartRhythm Case Rep. 2021 Feb; 7(2):106-108. Vanam S, Chindhy S, Han FT, Shen J. PMID: 33665112.
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    9. Contemporary procedural trends of Watchman percutaneous left atrial appendage occlusion in the United States. J Cardiovasc Electrophysiol. 2020 Nov 05. Munir MB, Khan MZ, Darden D, Pasupula DK, Balla S, Han FT, Reeves R, Hsu JC. PMID: 33155356.
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    10. Challenging case of J-wave syndromes. Heart. 2020 Nov; 106(22):1725-1780. Bui QM, Han F, Cotter B. PMID: 33115778.
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    11. Reproducibility of clinical late gadolinium enhancement magnetic resonance imaging in detecting left atrial scar after atrial fibrillation ablation. J Cardiovasc Electrophysiol. 2020 Nov; 31(11):2824-2832. Kamali R, Schroeder J, DiBella E, Steinberg B, Han F, Dosdall DJ, Macleod RS, Ranjan R. PMID: 32931635.
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    12. Comparison of Outcomes After Ablation of Atrial Fibrillation in Patients With Heart Failure With Preserved Versus Reduced Ejection Fraction. Am J Cardiol. 2020 12 01; 136:62-70. Aldaas OM, Malladi CL, Mylavarapu PS, Lupercio F, Darden D, Han FT, Hoffmayer KS, Krummen D, Ho G, Raissi F, Feld GK, Hsu JC. PMID: 32941815.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    13. Effect of closed loop stimulation versus accelerometer on outcomes with cardiac resynchronization therapy: the CLASS trial. J Interv Card Electrophysiol. 2020 Aug 05. Hsu JC, Darden D, Alegre M, Birgersdotter-Green U, Feld GK, Hoffmayer KS, Han F, Krummen D, Raissi F, Ho G, Taub PR, Urey MA, Adler E. PMID: 32757086.
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    14. Clinical factors associated with baseline history of atrial fibrillation and subsequent clinical outcomes following initial implantable cardioverter-defibrillator placement. Pacing Clin Electrophysiol. 2020 06; 43(6):542-550. Giancaterino S, Nishimura M, Birgersdotter-Green U, Hoffmayer KS, Han FT, Raissi F, Ho G, Krummen D, Feld GK, Hsu JC. PMID: 32297348.
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    15. Ablation of Supraventricular Tachycardias From Concealed Left-Sided Nodoventricular and Nodofascicular Accessory Pathways. Circ Arrhythm Electrophysiol. 2020 05; 13(5):e007853. Cardona-Guarache R, Han FT, Nguyen DT, Chicos AB, Badhwar N, Knight BP, Johnson CJ, Heaven D, Scheinman MM. PMID: 32286853.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    16. Systematic collection of patient-reported outcomes in atrial fibrillation: feasibility and initial results of the Utah mEVAL AF programme. Europace. 2020 03 01; 22(3):368-374. Steinberg BA, Turner J, Lyons A, Biber J, Chelu MG, Fang JC, Freedman RA, Han FT, Hardisty B, Marrouche NF, Ranjan R, Shah RU, Spertus JA, Stehlik J, Zenger B, Piccini JP, Hess R. PMID: 31702780.
      View in: PubMed   Mentions: 2     Fields:    
    17. P2Y12 inhibitors with oral anticoagulation for percutaneous coronary intervention with atrial fibrillation: a systematic review and meta-analysis. Heart. 2020 Apr; 106(8):575-583. Lupercio F, Giancaterino S, Villablanca PA, Han F, Hoffmayer K, Ho G, Raissi F, Krummen D, Birgersdotter-Green U, Feld G, Reeves R, Mahmud E, Hsu JC. PMID: 32034008.
      View in: PubMed   Mentions: 1     Fields:    
    18. Variants of accessory pathways. Pacing Clin Electrophysiol. 2020 01; 43(1):21-29. Hoffmayer KS, Han FT, Singh D, Scheinman MM. PMID: 31682283.
      View in: PubMed   Mentions: 3     Fields:    
    19. Ventricular arrhythmias in patients with biventricular assist devices. J Interv Card Electrophysiol. 2020 Sep; 58(3):243-252. Lin AY, Tran H, Brambatti M, Adler E, Pretorius V, Pollema T, Hsu JC, Feld GK, Hoffmayer K, Han F, Krummen D, Ho G. PMID: 31838665.
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    20. Role of adjunctive posterior wall isolation in patients undergoing atrial fibrillation ablation: a systematic review and meta-analysis. J Interv Card Electrophysiol. 2020 Jun; 58(1):77-86. Lupercio F, Lin AY, Aldaas OM, Romero J, Briceno D, Hoffmayer KS, Han FT, Di Biase L, Feld GK, Hsu JC. PMID: 31673901.
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    21. Meta-analysis of Effect of Modest (=10%) Weight Loss in Management of Overweight and Obese Patients With Atrial Fibrillation. Am J Cardiol. 2019 11 15; 124(10):1568-1574. Aldaas OM, Lupercio F, Han FT, Hoffmayer KS, Krummen D, Ho G, Raissi F, Birgersdotter-Green U, Feld GK, Hsu JC. PMID: 31540665.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    22. Predictors of rate-adaptive pacing in patients implanted with implantable cardioverter-defibrillator and subsequent differential clinical outcomes. J Interv Card Electrophysiol. 2019 Jun; 55(1):83-91. Källner N, Nishimura M, Birgersdotter-Green U, Hoffmayer KS, Han FT, Krummen DE, Raissi F, Feld GK, Hsu JC. PMID: 30929121.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    23. Atrial Fibrosis by Late Gadolinium Enhancement Magnetic Resonance Imaging and Catheter Ablation of Atrial Fibrillation: 5-Year Follow-Up Data. J Am Heart Assoc. 2018 12 04; 7(23):e006313. Chelu MG, King JB, Kholmovski EG, Ma J, Gal P, Marashly Q, AlJuaid MA, Kaur G, Silver MA, Johnson KA, Suksaranjit P, Wilson BD, Han FT, Elvan A, Marrouche NF. PMID: 30511895.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    24. High-Power Radiofrequency Catheter Ablation of Atrial Fibrillation: Using Late Gadolinium Enhancement Magnetic Resonance Imaging as a Novel Index of Esophageal Injury. JACC Clin Electrophysiol. 2018 12; 4(12):1583-1594. Baher A, Kheirkhahan M, Rechenmacher SJ, Marashly Q, Kholmovski EG, Siebermair J, Acharya M, Aljuaid M, Morris AK, Kaur G, Han FT, Wilson BD, Steinberg BA, Marrouche NF, Chelu MG. PMID: 30573123.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    25. Personalized virtual-heart technology for guiding the ablation of infarct-related ventricular tachycardia. Nat Biomed Eng. 2018 Oct; 2(10):732-740. Prakosa A, Arevalo HJ, Deng D, Boyle PM, Nikolov PP, Ashikaga H, Blauer JJE, Ghafoori E, Park CJ, Blake RC, Han FT, MacLeod RS, Halperin HR, Callans DJ, Ranjan R, Chrispin J, Nazarian S, Trayanova NA. PMID: 30847259.
      View in: PubMed   Mentions: 27     Fields:    
    26. Relation of Left Atrial Appendage Remodeling by Magnetic Resonance Imaging and Outcome of Ablation for Atrial Fibrillation. Am J Cardiol. 2018 07 01; 122(1):83-88. Suksaranjit P, Marrouche NF, Han FT, Morris A, Kaur G, Oswald T, Wilson BD. PMID: 29731119.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    27. Distance between the left atrium and the vertebral body is predictive of esophageal movement in serial MR imaging. J Interv Card Electrophysiol. 2018 Jul; 52(2):149-156. Yamashita K, Quang C, Schroeder JD, DiBella E, Han F, MacLeod R, Dosdall DJ, Ranjan R. PMID: 29532276.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    28. Durable lesion formation while avoiding esophageal injury during ablation of atrial fibrillation: Lessons learned from late gadolinium MR imaging. J Cardiovasc Electrophysiol. 2018 03; 29(3):385-392. Chelu MG, Morris AK, Kholmovski EG, King JB, Kaur G, Silver MA, Cates JE, Han FT, Marrouche NF. PMID: 29345381.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    29. Clinical Features and Sites of Ablation for Patients With Incessant Supraventricular Tachycardia From Concealed Nodofascicular and Nodoventricular Tachycardias. JACC Clin Electrophysiol. 2017 12 26; 3(13):1547-1556. Han FT, Riles EM, Badhwar N, Scheinman MM. PMID: 29759837.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    30. Left Atrial Fibrosis and Risk of Cerebrovascular and Cardiovascular Events in Patients With Atrial Fibrillation. J Am Coll Cardiol. 2017 Sep 12; 70(11):1311-1321. King JB, Azadani PN, Suksaranjit P, Bress AP, Witt DM, Han FT, Chelu MG, Silver MA, Biskupiak J, Wilson BD, Morris AK, Kholmovski EG, Marrouche N. PMID: 28882227.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    31. Long-term outcomes of minimally invasive surgical ablation for atrial fibrillation: A single-center experience. Heart Rhythm. 2017 09; 14(9):1281-1288. Saini A, Hu YL, Kasirajan V, Han FT, Khan MZ, Wolfe L, Gunda S, Koneru JN, Ellenbogen KA. PMID: 28438723.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCTClinical Trials
    32. Concealed Accessory Pathways with a Single Ventricular and Two Discrete Atrial Insertion Sites. Pacing Clin Electrophysiol. 2017 Mar; 40(3):255-263. Kipp RT, Abu Sham'a R, Hiroyuki I, Han FT, Refaat M, Hsu JC, Field ME, Kopp DE, Marcus GM, Scheinman MM, Hoffmayer KS. PMID: 28098354.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    33. A surgeon with symptomatic ventricular tachycardia while operating and exacerbated by left lateral decubitus position: Too much of a stretch? HeartRhythm Case Rep. 2017 Apr; 3(4):210-214. Khan F, Feld GK, Schricker A, Han FT, Hoffmayer KS, Hsu JC. PMID: 28491804.
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    34. Incessant Palpitations and Narrow Complex Tachycardia. Card Electrophysiol Clin. 2016 Mar; 8(1):61-5. Han FT. PMID: 26920171.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    35. An atrial fibrosis-based approach for atrial fibrillation ablation. Future Cardiol. 2015; 11(6):673-81. Han FT, Marrouche N. PMID: 26609731.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    36. Another Piece to the Puzzle: Linking the Cardiac Nervous System to Atrial Fibrillation in Pulmonary Arterial Hypertension. Hypertension. 2015 Nov; 66(5):935-7. Huston J, Han FT, Ryan JJ. PMID: 26418023.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    37. Shortness of breath and cardiac conduction abnormality caused by infiltrative cardiomyopathy. Eur Heart J. 2015 Sep 01; 36(33):2238. Suksaranjit P, Ryan JJ, Han FT, Nativi-Nicolau J, Revelo MP, Wilson BD. PMID: 26022004.
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    38. Sequential Percutaneous LAA Ligation and Pulmonary Vein Isolation in Patients with Persistent AF: Initial Results of a Feasibility Study. J Cardiovasc Electrophysiol. 2015 Jun; 26(6):608-14. Badhwar N, Lakkireddy D, Kawamura M, Han FT, Iyer SK, Moyers BS, Dewland TA, Woods C, Ferrell R, Nath J, Earnest M, Lee RJ. PMID: 25772569.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    39. Endocardial (Watchman) vs epicardial (Lariat) left atrial appendage exclusion devices: Understanding the differences in the location and type of leaks and their clinical implications. Heart Rhythm. 2015 Jul; 12(7):1501-7. Pillarisetti J, Reddy YM, Gunda S, Swarup V, Lee R, Rasekh A, Horton R, Massumi A, Cheng J, Bartus K, Badhwar N, Han F, Atkins D, Bommana S, Earnest M, Nath J, Ferrell R, Bormann S, Dawn B, Di Biase L, Mansour M, Natale A, Lakkireddy D. PMID: 25778430.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    40. Impact of left atrial appendage exclusion using an epicardial ligation system (LARIAT) on atrial fibrillation burden in patients with cardiac implantable electronic devices. Heart Rhythm. 2015 Jan; 12(1):52-9. Afzal MR, Kanmanthareddy A, Earnest M, Reddy M, Atkins D, Bommana S, Bartus K, Rasekh A, Han F, Badhwar N, Cheng J, Dibiase L, Ellis CR, Dawn B, Natale A, Lee RJ, Lakkireddy D. PMID: 25281005.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    41. Controlled Activation for Interrogation of the Electrophysiological Substrate. Comput Cardiol (2010). 2014 Sep 09; 2014:189-192. Blauer JJ, Han F, Ranjan R, Marrouche NF, MacLeod RS. PMID: 26478891.
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    42. A Practical Algorithm for Improving Localization and Quantification of Left Ventricular Scar. Comput Cardiol (2010). 2014 Sep 07; 2014:105-108. Zenger B, Cates J, Morris A, Kholmovski E, Au A, Ranjan R, Akoum N, McGann C, Wilson B, Marrouche N, Han FT, MacLeod RS. PMID: 26448961.
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    43. His overdrive pacing during supraventricular tachycardia: a novel maneuver for distinguishing atrioventricular nodal reentrant tachycardia from atrioventricular reciprocating tachycardia. Heart Rhythm. 2014 Aug; 11(8):1327-35. Singh DK, Viswanathan MN, Tanel RE, Lee RJ, Lee BK, Marcus GM, Olgin JE, Han F, Vedantham V, Tseng ZH, Pellegrini C, Kawamura M, Gerstenfeld EP, Badhwar N, Scheinman M. PMID: 24793458.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    44. The effects of LAA ligation on LAA electrical activity. Heart Rhythm. 2014 May; 11(5):864-870. Han FT, Bartus K, Lakkireddy D, Rojas F, Bednarek J, Kapelak B, Bartus M, Sadowski J, Badhwar N, Earnest M, Valderrabano M, Lee RJ. PMID: 24444443.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    45. Value of magnetic resonance imaging in guiding atrial fibrillation management. Can J Cardiol. 2013 Oct; 29(10):1194-202. Han FT, Akoum N, Marrouche N. PMID: 24074971.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    46. Trainee inexperience is associated with longer procedure times but no increase in complications for cardiac device implantation. Heart Rhythm. 2013 Dec; 10(12):1755-8. Soleimani Rahbar A, Hsu JC, Han FT, Nguyen N, Kwon M, Azadani PN, Marcus GM, Lee BK. PMID: 24016696.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    47. Diagnosis and ablation of multiform fascicular tachycardia. J Cardiovasc Electrophysiol. 2013 Mar; 24(3):297-304. Sung RK, Kim AM, Tseng ZH, Han F, Inada K, Tedrow UB, Viswanathan MN, Badhwar N, Varosy PD, Tanel R, Olgin JE, Stephenson WG, Scheinman M. PMID: 23110306.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    48. Percutaneous left atrial appendage suture ligation using the LARIAT device in patients with atrial fibrillation: initial clinical experience. J Am Coll Cardiol. 2013 Jul 09; 62(2):108-118. Bartus K, Han FT, Bednarek J, Myc J, Kapelak B, Sadowski J, Lelakowski J, Bartus S, Yakubov SJ, Lee RJ. PMID: 23062528.
      View in: PubMed   Mentions: 96     Fields:    Translation:Humans
    49. Direct measurement of the lethal isotherm for radiofrequency ablation of myocardial tissue. Circ Arrhythm Electrophysiol. 2011 Jun; 4(3):373-8. Wood M, Goldberg S, Lau M, Goel A, Alexander D, Han F, Feinstein S. PMID: 21406684.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    50. What is the time course of reversal of tachycardia-induced cardiomyopathy? Europace. 2011 Jan; 13(1):139-41. Han FT, Kiser R, Nixon JV, Wood MA, Ellenbogen KA. PMID: 20682551.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    51. Management of recurrent atrial arrhythmias after minimally invasive surgical pulmonary vein isolation and ganglionic plexi ablation for atrial fibrillation. Heart Rhythm. 2010 Apr; 7(4):445-51. Kron J, Kasirajan V, Wood MA, Kowalski M, Han FT, Ellenbogen KA. PMID: 20156608.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    52. Minimally invasive surgical atrial fibrillation ablation: patient selection and results. Heart Rhythm. 2009 Dec; 6(12 Suppl):S71-6. Han FT, Kasirajan V, Wood MA, Ellenbogen KA. PMID: 19864190.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    53. Effect of electrode orientation on lesion sizes produced by irrigated radiofrequency ablation catheters. J Cardiovasc Electrophysiol. 2009 Nov; 20(11):1262-8. Wood MA, Goldberg SM, Parvez B, Pathak V, Holland K, Ellenbogen AL, Han FT, Alexander D, Lau M, Reshko L, Goel A. PMID: 19572953.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    54. Results of a minimally invasive surgical pulmonary vein isolation and ganglionic plexi ablation for atrial fibrillation: single-center experience with 12-month follow-up. Circ Arrhythm Electrophysiol. 2009 Aug; 2(4):370-7. Han FT, Kasirajan V, Kowalski M, Kiser R, Wolfe L, Kalahasty G, Shepard RK, Wood MA, Ellenbogen KA. PMID: 19808492.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCTClinical Trials
    55. An anticonvulsant profile of the ketogenic diet in the rat. Epilepsy Res. 2002 Aug; 50(3):313-25. Bough KJ, Gudi K, Han FT, Rathod AH, Eagles DA. PMID: 12200222.
      View in: PubMed   Mentions: 24     Fields:    Translation:Animals
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