Paul Bushway

Title(s)	Associate Project Scientist, Medicine
School	Vc-health Sciences-schools
Address	9500 Gilman Drive # La Jolla CA 92093
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Bibliographic

Publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.

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Small-molecule probe reveals a kinase cascade that links stress signaling to TCF/LEF and Wnt responsiveness. Cell Chem Biol. 2021 05 20; 28(5):625-635.e5. Cheng J, Tsuda M, Okolotowicz K, Dwyer M, Bushway PJ, Colas AR, Lancman JJ, Schade D, Perea-Gil I, Bruyneel AAN, Lee J, Vadgama N, Quach J, McKeithan WL, Biechele TL, Wu JC, Moon RT, Si Dong PD, Karakikes I, Cashman JR, Mercola M. PMID: 33503403; PMCID: PMC8140986.

View in: PubMed Mentions: 2 Fields:
Bio Biochemistry Bio Biology Che Chemistry
Translation:Humans Animals Cells
Systemic AAV9.LAMP2B injection reverses metabolic and physiologic multiorgan dysfunction in a murine model of Danon disease. Sci Transl Med. 2020 03 18; 12(535). Manso AM, Hashem SI, Nelson BC, Gault E, Soto-Hermida A, Villarruel E, Brambatti M, Bogomolovas J, Bushway PJ, Chen C, Battiprolu P, Keravala A, Schwartz JD, Shah G, Gu Y, Dalton ND, Hammond K, Peterson K, Saftig P, Adler ED. PMID: 32188720.

View in: PubMed Mentions: 25 Fields:
Med Medicine (General)Sci Science
Translation:Humans Animals
Inflammasome inhibition blocks cardiac glycoside cell toxicity. J Biol Chem. 2019 08 23; 294(34):12846-12854. LaRock DL, Sands JS, Ettouati E, Richard M, Bushway PJ, Adler ED, Nizet V, LaRock CN. PMID: 31300552; PMCID: PMC6709640.

View in: PubMed Mentions: 9 Fields:
Bio Biochemistry
Translation:Humans Animals Cells
Small-Molecule Modulation of TDP-43 Recruitment to Stress Granules Prevents Persistent TDP-43 Accumulation in ALS/FTD. Neuron. 2019 09 04; 103(5):802-819.e11. Fang MY, Markmiller S, Vu AQ, Javaherian A, Dowdle WE, Jolivet P, Bushway PJ, Castello NA, Baral A, Chan MY, Linsley JW, Linsley D, Mercola M, Finkbeiner S, Lecuyer E, Lewcock JW, Yeo GW. PMID: 31272829; PMCID: PMC6728177.

View in: PubMed Mentions: 82 Fields:
Neu Neurology
Translation:Humans Cells
miRNAs that Induce Human Cardiomyocyte Proliferation Converge on the Hippo Pathway. Cell Rep. 2018 05 15; 23(7):2168-2174. Diez-Cuñado M, Wei K, Bushway PJ, Maurya MR, Perera R, Subramaniam S, Ruiz-Lozano P, Mercola M. PMID: 29768213; PMCID: PMC6261450.

View in: PubMed Mentions: 44 Fields:
Cel Cell Biology Mol Molecular Biology
Translation:Humans Cells
Id genes are essential for early heart formation. Genes Dev. 2017 07 01; 31(13):1325-1338. Cunningham TJ, Yu MS, McKeithan WL, Spiering S, Carrette F, Huang CT, Bushway PJ, Tierney M, Albini S, Giacca M, Mano M, Puri PL, Sacco A, Ruiz-Lozano P, Riou JF, Umbhauer M, Duester G, Mercola M, Colas AR. PMID: 28794185; PMCID: PMC5580654.

View in: PubMed Mentions: 35 Fields:
Mol Molecular Biology
Translation:Humans Animals Cells
Notch-independent RBPJ controls angiogenesis in the adult heart. Nat Commun. 2016 06 30; 7:12088. Díaz-Trelles R, Scimia MC, Bushway P, Tran D, Monosov A, Monosov E, Peterson K, Rentschler S, Cabrales P, Ruiz-Lozano P, Mercola M. PMID: 27357444; PMCID: PMC4931341.

View in: PubMed Mentions: 25 Fields:
Bio Biology Sci Science
Translation:Humans Animals Cells
Epicardial FSTL1 reconstitution regenerates the adult mammalian heart. Nature. 2015 Sep 24; 525(7570):479-85. Wei K, Serpooshan V, Hurtado C, Diez-Cuñado M, Zhao M, Maruyama S, Zhu W, Fajardo G, Noseda M, Nakamura K, Tian X, Liu Q, Wang A, Matsuura Y, Bushway P, Cai W, Savchenko A, Mahmoudi M, Schneider MD, van den Hoff MJ, Butte MJ, Yang PC, Walsh K, Zhou B, Bernstein D, Mercola M, Ruiz-Lozano P. PMID: 26375005; PMCID: PMC4762253.

View in: PubMed Mentions: 219 Fields:
Sci Science
Translation:Humans Animals Cells
1,5-Disubstituted benzimidazoles that direct cardiomyocyte differentiation from mouse embryonic stem cells. Bioorg Med Chem. 2015 Sep 01; 23(17):5282-92. Okolotowicz KJ, Bushway P, Lanier M, Gilley C, Mercola M, Cashman JR. PMID: 26278027; PMCID: PMC4766108.

View in: PubMed Mentions: 1 Fields:
Bio Biochemistry Che Chemistry
Translation:Animals Cells
High content screening for modulators of cardiac differentiation in human pluripotent stem cells. Methods Mol Biol. 2015; 1263:43-61. Spiering S, Davidovics H, Bushway PJ, Mercola M, Willems E. PMID: 25618335; PMCID: PMC4766105.

View in: PubMed Mentions: 1 Fields:
Mol Molecular Biology
Translation:Humans Cells
Whole-genome microRNA screening identifies let-7 and mir-18 as regulators of germ layer formation during early embryogenesis. Genes Dev. 2012 Dec 01; 26(23):2567-79. Colas AR, McKeithan WL, Cunningham TJ, Bushway PJ, Garmire LX, Duester G, Subramaniam S, Mercola M. PMID: 23152446; PMCID: PMC3521625.

View in: PubMed Mentions: 31 Fields:
Mol Molecular Biology
Translation:Animals Cells
Synthesis and SAR of b-annulated 1,4-dihydropyridines define cardiomyogenic compounds as novel inhibitors of TGFβ signaling. J Med Chem. 2012 Nov 26; 55(22):9946-57. Schade D, Lanier M, Willems E, Okolotowicz K, Bushway P, Wahlquist C, Gilley C, Mercola M, Cashman JR. PMID: 23130626; PMCID: PMC3518459.

View in: PubMed Mentions: 13 Fields:
Che Chemistry
Translation:Humans Animals Cells
Serum-free generation of multipotent mesoderm (Kdr+) progenitor cells in mouse embryonic stem cells for functional genomics screening. Curr Protoc Stem Cell Biol. 2012 Nov; Chapter 1:Unit 1F.13. McKeithan WL, Colas AR, Bushway PJ, Ray S, Mercola M. PMID: 23154934; PMCID: PMC3562707.

View in: PubMed Mentions: 4 Fields:
Cel Cell Biology
Translation:Animals Cells
Small molecule-mediated TGF-β type II receptor degradation promotes cardiomyogenesis in embryonic stem cells. Cell Stem Cell. 2012 Aug 03; 11(2):242-52. Willems E, Cabral-Teixeira J, Schade D, Cai W, Reeves P, Bushway PJ, Lanier M, Walsh C, Kirchhausen T, Izpisua Belmonte JC, Cashman J, Mercola M. PMID: 22862949; PMCID: PMC3419596.

View in: PubMed Mentions: 64 Fields:
Cel Cell Biology
Translation:Humans Animals Cells
HNF4α antagonists discovered by a high-throughput screen for modulators of the human insulin promoter. Chem Biol. 2012 Jul 27; 19(7):806-18. Kiselyuk A, Lee SH, Farber-Katz S, Zhang M, Athavankar S, Cohen T, Pinkerton AB, Ye M, Bushway P, Richardson AD, Hostetler HA, Rodriguez-Lee M, Huang L, Spangler B, Smith L, Higginbotham J, Cashman J, Freeze H, Itkin-Ansari P, Dawson MI, Schroeder F, Cang Y, Mercola M, Levine F. PMID: 22840769; PMCID: PMC3447631.

View in: PubMed Mentions: 39 Fields:
Bio Biochemistry Bio Biology Che Chemistry
Translation:Humans Cells
Optimization and application of median filter corrections to relieve diverse spatial patterns in microtiter plate data. J Biomol Screen. 2011 Oct; 16(9):1068-80. Bushway PJ, Azimi B, Heynen-Genel S. PMID: 21900202; PMCID: PMC4079548.

View in: PubMed Mentions: Fields:
Mol Molecular Biology
Hybrid median filter background estimator for correcting distortions in microtiter plate data. Assay Drug Dev Technol. 2010 Apr; 8(2):238-50. Bushway PJ, Azimi B, Heynen-Genel S, Price JH, Mercola M. PMID: 20230301; PMCID: PMC3096555.

View in: PubMed Mentions: 2 Fields:
Che Chemistry Techniques Pha Pharmacology
Translation:Animals Cells
Natural and synthetic regulators of embryonic stem cell cardiogenesis. Pediatr Cardiol. 2009 Jul; 30(5):635-42. Willems E, Bushway PJ, Mercola M. PMID: 19319460; PMCID: PMC3478151.

View in: PubMed Mentions: 22 Fields:
Car Cardiology Ped Pediatrics
Translation:Humans Cells
A comparative analysis of standard microtiter plate reading versus imaging in cellular assays. Assay Drug Dev Technol. 2008 Aug; 6(4):557-67. Bushway PJ, Mercola M, Price JH. PMID: 18795873; PMCID: PMC2956680.

View in: PubMed Mentions: 8 Fields:
Che Chemistry Techniques Pha Pharmacology
Translation:Cells
High-throughput screening for modulators of stem cell differentiation. Methods Enzymol. 2006; 414:300-16. Bushway PJ, Mercola M. PMID: 17110199.

View in: PubMed Mentions: 12 Fields:
Bio Biochemistry
Translation:Humans Animals Cells
SWAP-70-like adapter of T cells, an adapter protein that regulates early TCR-initiated signaling in Th2 lineage cells. Immunity. 2003 Mar; 18(3):403-14. Tanaka Y, Bi K, Kitamura R, Hong S, Altman Y, Matsumoto A, Tabata H, Lebedeva S, Bushway PJ, Altman A. PMID: 12648457.

View in: PubMed Mentions: 44 Fields:
All Allergy and Immunology
Translation:Animals Cells
Protein kinase C-theta mediates a selective T cell survival signal via phosphorylation of BAD. J Immunol. 2001 May 15; 166(10):5955-63. Villalba M, Bushway P, Altman A. PMID: 11342610.

View in: PubMed Mentions: 20 Fields:
All Allergy and Immunology
Translation:Humans Cells