Paul Bushway

Title(s)Assistant Project Scientist, Medicine
SchoolHealth Sciences
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. LaRock DL, Sands JS, Ettouati E, Richard M, Bushway PJ, Adler ED, Nizet V, LaRock CN. Inflammasome inhibition blocks cardiac glycoside cell toxicity. J Biol Chem. 2019 Jul 12. PMID: 31300552.
      View in: PubMed
    2. Fang MY, Markmiller S, Vu AQ, Javaherian A, Dowdle WE, Jolivet P, Bushway PJ, Castello NA, Baral A, Chan MY, Linsley JW, Linsley D, Mercola M, Finkbeiner S, Lecuyer E, Lewcock JW, Yeo GW. Small-Molecule Modulation of TDP-43 Recruitment to Stress Granules Prevents Persistent TDP-43 Accumulation in ALS/FTD. Neuron. 2019 Jun 18. PMID: 31272829.
      View in: PubMed
    3. Diez-Cuñado M, Wei K, Bushway PJ, Maurya MR, Perera R, Subramaniam S, Ruiz-Lozano P, Mercola M. miRNAs that Induce Human Cardiomyocyte Proliferation Converge on the Hippo Pathway. Cell Rep. 2018 May 15; 23(7):2168-2174. PMID: 29768213.
      View in: PubMed
    4. Cunningham TJ, Yu MS, McKeithan WL, Spiering S, Carrette F, Huang CT, Bushway PJ, Tierney M, Albini S, Giacca M, Mano M, Puri PL, Sacco A, Ruiz-Lozano P, Riou JF, Umbhauer M, Duester G, Mercola M, Colas AR. Id genes are essential for early heart formation. Genes Dev. 2017 07 01; 31(13):1325-1338. PMID: 28794185.
      View in: PubMed
    5. Díaz-Trelles R, Scimia MC, Bushway P, Tran D, Monosov A, Monosov E, Peterson K, Rentschler S, Cabrales P, Ruiz-Lozano P, Mercola M. Notch-independent RBPJ controls angiogenesis in the adult heart. Nat Commun. 2016 06 30; 7:12088. PMID: 27357444.
      View in: PubMed
    6. Wei K, Serpooshan V, Hurtado C, Diez-Cuñado M, Zhao M, Maruyama S, Zhu W, Fajardo G, Noseda M, Nakamura K, Tian X, Liu Q, Wang A, Matsuura Y, Bushway P, Cai W, Savchenko A, Mahmoudi M, Schneider MD, van den Hoff MJ, Butte MJ, Yang PC, Walsh K, Zhou B, Bernstein D, Mercola M, Ruiz-Lozano P. Epicardial FSTL1 reconstitution regenerates the adult mammalian heart. Nature. 2015 Sep 24; 525(7570):479-85. PMID: 26375005; PMCID: PMC4762253.
    7. Okolotowicz KJ, Bushway P, Lanier M, Gilley C, Mercola M, Cashman JR. 1,5-Disubstituted benzimidazoles that direct cardiomyocyte differentiation from mouse embryonic stem cells. Bioorg Med Chem. 2015 Sep 01; 23(17):5282-92. PMID: 26278027; PMCID: PMC4766108.
    8. Spiering S, Davidovics H, Bushway PJ, Mercola M, Willems E. High content screening for modulators of cardiac differentiation in human pluripotent stem cells. Methods Mol Biol. 2015; 1263:43-61. PMID: 25618335; PMCID: PMC4766105.
    9. Colas AR, McKeithan WL, Cunningham TJ, Bushway PJ, Garmire LX, Duester G, Subramaniam S, Mercola M. Whole-genome microRNA screening identifies let-7 and mir-18 as regulators of germ layer formation during early embryogenesis. Genes Dev. 2012 Dec 01; 26(23):2567-79. PMID: 23152446; PMCID: PMC3521625.
    10. Schade D, Lanier M, Willems E, Okolotowicz K, Bushway P, Wahlquist C, Gilley C, Mercola M, Cashman JR. Synthesis and SAR of b-annulated 1,4-dihydropyridines define cardiomyogenic compounds as novel inhibitors of TGFß signaling. J Med Chem. 2012 Nov 26; 55(22):9946-57. PMID: 23130626; PMCID: PMC3518459.
    11. McKeithan WL, Colas AR, Bushway PJ, Ray S, Mercola M. Serum-free generation of multipotent mesoderm (Kdr+) progenitor cells in mouse embryonic stem cells for functional genomics screening. Curr Protoc Stem Cell Biol. 2012 Nov; Chapter 1:Unit 1F.13. PMID: 23154934; PMCID: PMC3562707.
    12. Willems E, Cabral-Teixeira J, Schade D, Cai W, Reeves P, Bushway PJ, Lanier M, Walsh C, Kirchhausen T, Izpisua Belmonte JC, Cashman J, Mercola M. Small molecule-mediated TGF-ß type II receptor degradation promotes cardiomyogenesis in embryonic stem cells. Cell Stem Cell. 2012 Aug 03; 11(2):242-52. PMID: 22862949; PMCID: PMC3419596.
    13. Kiselyuk A, Lee SH, Farber-Katz S, Zhang M, Athavankar S, Cohen T, Pinkerton AB, Ye M, Bushway P, Richardson AD, Hostetler HA, Rodriguez-Lee M, Huang L, Spangler B, Smith L, Higginbotham J, Cashman J, Freeze H, Itkin-Ansari P, Dawson MI, Schroeder F, Cang Y, Mercola M, Levine F. HNF4a antagonists discovered by a high-throughput screen for modulators of the human insulin promoter. Chem Biol. 2012 Jul 27; 19(7):806-18. PMID: 22840769; PMCID: PMC3447631.
    14. Bushway PJ, Azimi B, Heynen-Genel S. Optimization and application of median filter corrections to relieve diverse spatial patterns in microtiter plate data. J Biomol Screen. 2011 Oct; 16(9):1068-80. PMID: 21900202; PMCID: PMC4079548.
    15. Bushway PJ, Azimi B, Heynen-Genel S, Price JH, Mercola M. Hybrid median filter background estimator for correcting distortions in microtiter plate data. Assay Drug Dev Technol. 2010 Apr; 8(2):238-50. PMID: 20230301; PMCID: PMC3096555.
    16. Willems E, Bushway PJ, Mercola M. Natural and synthetic regulators of embryonic stem cell cardiogenesis. Pediatr Cardiol. 2009 Jul; 30(5):635-42. PMID: 19319460; PMCID: PMC3478151.
    17. Bushway PJ, Mercola M, Price JH. A comparative analysis of standard microtiter plate reading versus imaging in cellular assays. Assay Drug Dev Technol. 2008 Aug; 6(4):557-67. PMID: 18795873; PMCID: PMC2956680.
    18. Bushway PJ, Mercola M. High-throughput screening for modulators of stem cell differentiation. Methods Enzymol. 2006; 414:300-16. PMID: 17110199.
      View in: PubMed
    19. Tanaka Y, Bi K, Kitamura R, Hong S, Altman Y, Matsumoto A, Tabata H, Lebedeva S, Bushway PJ, Altman A. SWAP-70-like adapter of T cells, an adapter protein that regulates early TCR-initiated signaling in Th2 lineage cells. Immunity. 2003 Mar; 18(3):403-14. PMID: 12648457.
      View in: PubMed
    20. Villalba M, Bi K, Hu J, Altman Y, Bushway P, Reits E, Neefjes J, Baier G, Abraham RT, Altman A. Translocation of PKC[theta] in T cells is mediated by a nonconventional, PI3-K- and Vav-dependent pathway, but does not absolutely require phospholipase C. J Cell Biol. 2002 Apr 15; 157(2):253-63. PMID: 11956228; PMCID: PMC2199257.