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Vijay Sharma

TitleSenate Emeritus
InstitutionUniversity of California San Diego
DepartmentMedicine
Address9500 Gilman Drive #0652
La Jolla CA 92093
Phone858-822-2918
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    Collapse Research Activities and Funding
    ACTIVATION OF GUANYLATE CYCLASE BY NITRIC OXIDE
    NIH/NHLBI R01HL048014Feb 1, 1993 - Jan 31, 1998
    Role: Principal Investigator
    MECHANISM OF REACTIONS OF HEMOGLOBIN WITH LIGANDS
    NIH/NHLBI R55HL031159Sep 1, 1976 - Sep 29, 1995
    Role: Principal Investigator
    MECHANISM OF REACTIONS OF HEMOGLOBIN WITH LIGANDS
    NIH/NHLBI R01HL031159Sep 1, 1976 - Sep 29, 1992
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Brenner M, Kim JG, Mahon SB, Lee J, Kreuter KA, Blackledge W, Mukai D, Patterson S, Mohammad O, Sharma V, Boss GR. Intramuscular cobinamide sulfite in a rabbit model of sublethal cyanide toxicity. Ann Emerg Med. 2010 Apr; 55(4):352-63. PMID: 20045579; PMCID: PMC2963429.
    2. Brenner M, Mahon SB, Lee J, Kim J, Mukai D, Goodman S, Kreuter KA, Ahdout R, Mohammad O, Sharma V, Blackledge W, Boss GR. Comparison of cobinamide to hydroxocobalamin in reversing cyanide physiologic effects in rabbits using diffuse optical spectroscopy monitoring. J Biomed Opt. 2010 Jan-Feb; 15(1):017001. PMID: 20210475; PMCID: PMC2816993.
    3. Broderick KE, Chan A, Balasubramanian M, Feala J, Reed SL, Panda M, Sharma V, Pilz RB, Bigby TD, Boss GR. Cyanide produced by human isolates of Pseudomonas aeruginosa contributes to lethality in Drosophila melanogaster. J Infect Dis. 2008 Feb 01; 197(3):457-64. PMID: 18199034.
      View in: PubMed
    4. Broderick KE, Alvarez L, Balasubramanian M, Belke DD, Makino A, Chan A, Woods VL, Dillmann WH, Sharma V, Pilz RB, Bigby TD, Boss GR. Nitrosyl-cobinamide, a new and direct nitric oxide releasing drug effective in vivo. Exp Biol Med (Maywood). 2007 Dec; 232(11):1432-40. PMID: 18040067.
      View in: PubMed
    5. Broderick KE, Balasubramanian M, Chan A, Potluri P, Feala J, Belke DD, McCulloch A, Sharma V, Pilz RB, Bigby TD, Boss GR. The cobalamin precursor cobinamide detoxifies nitroprusside-generated cyanide. Exp Biol Med (Maywood). 2007 Jun; 232(6):789-98. PMID: 17526771.
      View in: PubMed
    6. Broderick KE, Feala J, McCulloch A, Paternostro G, Sharma V, Pilz RB, Boss GR. The nitric oxide scavenger cobinamide profoundly improves survival in a Drosophila melanogaster model of bacterial sepsis. FASEB J. 2006 Sep; 20(11):1865-73. PMID: 16940158.
      View in: PubMed
    7. Broderick KE, Potluri P, Zhuang S, Scheffler IE, Sharma V, Pilz RB, Boss GR. Cyanide detoxification by the cobalamin precursor cobinamide. Exp Biol Med (Maywood). 2006 May; 231(5):641-9. PMID: 16636313.
      View in: PubMed
    8. Kambo A, Sharma V, Casteel DE, Woods VL, Pilz RB, Boss GR. Nitric oxide inhibits mammalian methylmalonyl-CoA mutase. J Biol Chem. 2005 Mar 18; 280(11):10073-82. PMID: 15647267.
      View in: PubMed
    9. Broderick KE, Singh V, Zhuang S, Kambo A, Chen JC, Sharma V, Pilz RB, Boss GR. Nitric oxide scavenging by the cobalamin precursor cobinamide. J Biol Chem. 2005 Mar 11; 280(10):8678-85. PMID: 15632180.
      View in: PubMed
    10. Sharma V, Pilz RB, Boss GR, Magde D. Reactions of nitric oxide with vitamin B12 and its precursor, cobinamide. Biochemistry. 2003 Jul 29; 42(29):8900-8. PMID: 12873151.
      View in: PubMed
    11. Zemojtel T, Scheele JS, Martásek P, Masters BS, Sharma V, Magde D. Role of the interdomain linker probed by kinetics of CO ligation to an endothelial nitric oxide synthase mutant lacking the calmodulin binding peptide (residues 503-517 in bovine). Biochemistry. 2003 Jun 03; 42(21):6500-6. PMID: 12767233.
      View in: PubMed
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