Wouter Rappel

Title(s)Researcher, Physics
SchoolVc-academic Affairs
Address9500 Gilman Drive #
La Jolla CA 92093
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    Patient-directed Computational Analysis of Atrial Fibrillation
    NIH R01HL122384Jan 12, 2015 - Dec 31, 2018
    Role: Principal Investigator
    CHEMOTAXIS IN DICTYOSTELIUM DISCOIDEUM: AN INTEGRATIVE APPROACH
    NIH P01GM078586Jul 1, 2006 - Jul 31, 2017
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Eukaryotic Chemotaxis under Periodic Stimulation Shows Temporal Gradient Dependence. Phys Rev Lett. 2024 Aug 09; 133(6):068401. Karmakar R, Karanam A, Tang MH, Rappel WJ. PMID: 39178438.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    2. Annihilation dynamics during spiral defect chaos revealed by particle models. Chaos. 2024 May 01; 34(5). Tyree TJ, Murphy P, Rappel WJ. PMID: 38787314; PMCID: PMC11141445.
      View in: PubMed   Mentions:    Fields:    
    3. Annihilation dynamics during spiral defect chaos revealed by particle models. ArXiv. 2024 Feb 15. Tyree TJ, Murphy P, Rappel WJ. PMID: 38410644; PMCID: PMC10896354.
      View in: PubMed   Mentions:
    4. Spatially Conserved Spiral Wave Activity During Human Atrial Fibrillation. Circ Arrhythm Electrophysiol. 2024 03; 17(3):e012041. Rappel WJ, Baykaner T, Zaman J, Ganesan P, Rogers AJ, Narayan SM. PMID: 38348685; PMCID: PMC10950516.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    5. Quantifying a spectrum of clinical response in atrial tachyarrhythmias using spatiotemporal synchronization of electrograms. Europace. 2023 05 19; 25(5). Ganesan P, Deb B, Feng R, Rodrigo M, Ruiperez-Campillo S, Rogers AJ, Clopton P, Wang PJ, Zeemering S, Schotten U, Rappel WJ, Narayan SM. PMID: 36932716; PMCID: PMC10227659.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    6. A role for ethylene signaling and biosynthesis in regulating and accelerating CO2 - and abscisic acid-mediated stomatal movements in Arabidopsis. New Phytol. 2023 06; 238(6):2460-2475. Azoulay-Shemer T, Schulze S, Nissan-Roda D, Bosmans K, Shapira O, Weckwerth P, Zamora O, Yarmolinsky D, Trainin T, Kollist H, Huffaker A, Rappel WJ, Schroeder JI. PMID: 36994603; PMCID: PMC10259821.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    7. Boolean modelling in plant biology. Quant Plant Biol. 2022; 3:e29. Karanam A, Rappel WJ. PMID: 37077966; PMCID: PMC10095905.
      View in: PubMed   Mentions: 1  
    8. Predicting acute termination and non-termination during ablation of human atrial fibrillation using quantitative indices. Front Physiol. 2022; 13:939350. Kappel C, Reiss M, Rodrigo M, Ganesan P, Narayan SM, Rappel WJ. PMID: 36483297; PMCID: PMC9725096.
      View in: PubMed   Mentions: 1  
    9. The physics of heart rhythm disorders. Phys Rep. 2022 Sep 19; 978:1-45. Rappel WJ. PMID: 36843637; PMCID: PMC9949723.
      View in: PubMed   Mentions: 4  
    10. Stochastic termination of spiral wave dynamics in cardiac tissue. Front Netw Physiol. 2022 Jan; 2. Rappel WJ, Krummen DE, Baykaner T, Zaman J, Donsky A, Swarup V, Miller JM, Narayan SM. PMID: 36187938; PMCID: PMC9524168.
      View in: PubMed   Mentions: 9  
    11. Intermittent trapping of spiral waves in a cardiac model. Phys Rev E. 2022 Jan; 105(1-1):014404. Rappel WJ. PMID: 35193211; PMCID: PMC9020409.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    12. Deep dive into CO2-dependent molecular mechanisms driving stomatal responses in plants. Plant Physiol. 2021 12 04; 187(4):2032-2042. Dubeaux G, Hsu PK, Ceciliato PHO, Swink KJ, Rappel WJ, Schroeder JI. PMID: 35142859; PMCID: PMC8644143.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    13. Boolink: a graphical interface for open access Boolean network simulations and use in guard cell CO2 signaling. Plant Physiol. 2021 12 04; 187(4):2311-2322. Karanam A, He D, Hsu PK, Schulze S, Dubeaux G, Karmakar R, Schroeder JI, Rappel WJ. PMID: 34618035; PMCID: PMC8644243.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    14. Coupling traction force patterns and actomyosin wave dynamics reveals mechanics of cell motion. Mol Syst Biol. 2021 12; 17(12):e10505. Ghabache E, Cao Y, Miao Y, Groisman A, Devreotes PN, Rappel WJ. PMID: 34898015; PMCID: PMC8666840.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    15. Three dimensional reconstruction to visualize atrial fibrillation activation patterns on curved atrial geometry. PLoS One. 2021; 16(4):e0249873. Abad R, Collart O, Ganesan P, Rogers AJ, Alhusseini MI, Rodrigo M, Narayan SM, Rappel WJ. PMID: 33836026; PMCID: PMC8034734.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    16. The mechanics and dynamics of cancer cells sensing noisy 3D contact guidance. Proc Natl Acad Sci U S A. 2021 03 09; 118(10). Kim J, Cao Y, Eddy C, Deng Y, Levine H, Rappel WJ, Sun B. PMID: 33658384; PMCID: PMC7958230.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    17. Cell dispersal by localized degradation of a chemoattractant. Proc Natl Acad Sci U S A. 2021 02 09; 118(6). Karmakar R, Tyree T, Gomer RH, Rappel WJ. PMID: 33526658; PMCID: PMC8017704.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    18. Electrical Substrate Ablation for Refractory Ventricular Fibrillation: Results of the AVATAR Study. Circ Arrhythm Electrophysiol. 2021 03; 14(3):e008868. Krummen DE, Ho G, Hoffmayer KS, Schweis FN, Baykaner T, Rogers AJ, Han FT, Hsu JC, Viswanathan MN, Wang PJ, Rappel WJ, Narayan SM. PMID: 33550811; PMCID: PMC7990504.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    19. Cellular memory in eukaryotic chemotaxis depends on the background chemoattractant concentration. Phys Rev E. 2021 Jan; 103(1-1):012402. Karmakar R, Tang MH, Yue H, Lombardo D, Karanam A, Camley BA, Groisman A, Rappel WJ. PMID: 33601617.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    20. Tissue topography steers migrating Drosophila border cells. Science. 2020 11 20; 370(6519):987-990. Dai W, Guo X, Cao Y, Mondo JA, Campanale JP, Montell BJ, Burrous H, Streichan S, Gov N, Rappel WJ, Montell DJ. PMID: 33214282; PMCID: PMC8103818.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    21. Machine Learned Cellular Phenotypes in Cardiomyopathy Predict Sudden Death. Circ Res. 2021 01 22; 128(2):172-184. Rogers AJ, Selvalingam A, Alhusseini MI, Krummen DE, Corrado C, Abuzaid F, Baykaner T, Meyer C, Clopton P, Giles W, Bailis P, Niederer S, Wang PJ, Rappel WJ, Zaharia M, Narayan SM. PMID: 33167779; PMCID: PMC7855939.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    22. Novel micropatterning technique reveals dependence of cell-substrate adhesion and migration of social amoebas on parental strain, development, and fluorescent markers. PLoS One. 2020; 15(7):e0236171. Karmakar R, Schich C, Kamprad N, Scheller V, Gutierrez E, Groisman A, Rappel WJ, Tarantola M. PMID: 32702047; PMCID: PMC7377449.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    23. Machine Learning to Classify Intracardiac Electrical Patterns During Atrial Fibrillation: Machine Learning of Atrial Fibrillation. Circ Arrhythm Electrophysiol. 2020 08; 13(8):e008160. Alhusseini MI, Abuzaid F, Rogers AJ, Zaman JAB, Baykaner T, Clopton P, Bailis P, Zaharia M, Wang PJ, Rappel WJ, Narayan SM. PMID: 32631100; PMCID: PMC7438307.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    24. Termination of persistent atrial fibrillation by ablating sites that control large atrial areas. Europace. 2020 06 01; 22(6):897-905. Bhatia NK, Rogers AJ, Krummen DE, Hossainy S, Sauer W, Miller JM, Alhusseini MI, Peszek A, Armenia E, Baykaner T, Brachmann J, Turakhia MP, Clopton P, Wang PJ, Rappel WJ, Narayan SM. PMID: 32243508; PMCID: PMC7273336.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    25. Flower-like patterns in multi-species bacterial colonies. Elife. 2020 01 14; 9. Xiong L, Cao Y, Cooper R, Rappel WJ, Hasty J, Tsimring L. PMID: 31933477; PMCID: PMC6959979.
      View in: PubMed   Mentions: 15     Fields:    Translation:Cells
    26. A minimal computational model for three-dimensional cell migration. J R Soc Interface. 2019 12; 16(161):20190619. Cao Y, Ghabache E, Miao Y, Niman C, Hakozaki H, Reck-Peterson SL, Devreotes PN, Rappel WJ. PMID: 31847757; PMCID: PMC6936042.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    27. Response by Bhatia et al to Letter Regarding Article, "Wavefront Field Mapping Reveals a Physiologic Network Between Drivers Where Ablation Terminates Atrial Fibrillation". Circ Arrhythm Electrophysiol. 2019 11; 12(11):e008022. Bhatia NK, Rappel WJ, Narayan SM. PMID: 31726861; PMCID: PMC7365521.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    28. Plasticity of cell migration resulting from mechanochemical coupling. Elife. 2019 10 18; 8. Cao Y, Ghabache E, Rappel WJ. PMID: 31625907; PMCID: PMC6799977.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    29. Wavefront Field Mapping Reveals a Physiologic Network Between Drivers Where Ablation Terminates Atrial Fibrillation. Circ Arrhythm Electrophysiol. 2019 08; 12(8):e006835. Leef G, Shenasa F, Bhatia NK, Rogers AJ, Sauer W, Miller JM, Swerdlow M, Tamboli M, Alhusseini MI, Armenia E, Baykaner T, Brachmann J, Turakhia MP, Atienza F, Rappel WJ, Wang PJ, Narayan SM. PMID: 31352796; PMCID: PMC6666420.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    30. Chaotic tip trajectories of a single spiral wave in the presence of heterogeneities. Phys Rev E. 2019 Jun; 99(6-1):062409. Lombardo DM, Rappel WJ. PMID: 31330597; PMCID: PMC7296979.
      View in: PubMed   Mentions: 4     Fields:    
    31. Cell motility dependence on adhesive wetting. Soft Matter. 2019 Feb 27; 15(9):2043-2050. Cao Y, Karmakar R, Ghabache E, Gutierrez E, Zhao Y, Groisman A, Levine H, Camley BA, Rappel WJ. PMID: 30724956.
      View in: PubMed   Mentions: 11     Fields:    Translation:Animals
    32. Extinction dynamics of spiral defect chaos. Phys Rev E. 2019 Jan; 99(1-1):012407. Vidmar D, Rappel WJ. PMID: 30780268; PMCID: PMC6555560.
      View in: PubMed   Mentions: 11     Fields:    
    33. Insights into the Molecular Mechanisms of CO2-Mediated Regulation of Stomatal Movements. Curr Biol. 2018 12 03; 28(23):R1356-R1363. Zhang J, De-Oliveira-Ceciliato P, Takahashi Y, Schulze S, Dubeaux G, Hauser F, Azoulay-Shemer T, Tõldsepp K, Kollist H, Rappel WJ, Schroeder JI. PMID: 30513335.
      View in: PubMed   Mentions: 32     Fields:    Translation:Cells
    34. Identification of SLAC1 anion channel residues required for CO2/bicarbonate sensing and regulation of stomatal movements. Proc Natl Acad Sci U S A. 2018 10 30; 115(44):11129-11137. Zhang J, Wang N, Miao Y, Hauser F, McCammon JA, Rappel WJ, Schroeder JI. PMID: 30301791; PMCID: PMC6217375.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    35. Characterizing Electrogram Signal Fidelity and the Effects of Signal Contamination on Mapping Human Persistent Atrial Fibrillation. Front Physiol. 2018; 9:1232. Vidmar D, Alhusseini MI, Narayan SM, Rappel WJ. PMID: 30237766; PMCID: PMC6135945.
      View in: PubMed   Mentions: 1  
    36. Minimal Network Topologies for Signal Processing during Collective Cell Chemotaxis. Biophys J. 2018 06 19; 114(12):2986-2999. Yue H, Camley BA, Rappel WJ. PMID: 29925034; PMCID: PMC6026449.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    37. The cAMP-induced G protein subunits dissociation monitored in live Dictyostelium cells by BRET reveals two activation rates, a positive effect of caffeine and potential role of microtubules. Cell Signal. 2018 Aug; 48:25-37. Tariqul Islam AFM, Yue H, Scavello M, Haldeman P, Rappel WJ, Charest PG. PMID: 29698704; PMCID: PMC6453136.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    38. Successful ventricular fibrillation functional substrate ablation via a single vascular access site. HeartRhythm Case Rep. 2018 May; 4(5):173-176. Ho G, Hoffmayer KS, Villongco CT, Vidmar D, Rappel WJ, Krummen DE. PMID: 29915711; PMCID: PMC6003783.
      View in: PubMed   Mentions: 1  
    39. Identification and Characterization of Sites Where Persistent Atrial Fibrillation Is Terminated by Localized Ablation. Circ Arrhythm Electrophysiol. 2018 01; 11(1):e005258. Zaman JAB, Sauer WH, Alhusseini MI, Baykaner T, Borne RT, Kowalewski CAB, Busch S, Zei PC, Park S, Viswanathan MN, Wang PJ, Brachmann J, Krummen DE, Miller JM, Rappel WJ, Narayan SM, Peters NS. PMID: 29330332; PMCID: PMC5769709.
      View in: PubMed   Mentions: 33     Fields:    Translation:Humans
    40. Adaptation of Living Systems. Annu Rev Condens Matter Phys. 2018 Mar; 9:183-205. Tu Y, Rappel WJ. PMID: 30057689; PMCID: PMC6060625.
      View in: PubMed   Mentions: 15  
    41. Cell-to-cell variation sets a tissue-rheology-dependent bound on collective gradient sensing. Proc Natl Acad Sci U S A. 2017 11 21; 114(47):E10074-E10082. Camley BA, Rappel WJ. PMID: 29114053; PMCID: PMC5703308.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    42. To the Editor- On the deformation and interpolation of phase maps. Heart Rhythm. 2018 02; 15(2):e3. Vidmar D, Rappel WJ. PMID: 29113882; PMCID: PMC5836728.
      View in: PubMed   Mentions: 1     Fields:    
    43. Systematic reduction of a detailed atrial myocyte model. Chaos. 2017 Sep; 27(9):093914. Lombardo DM, Rappel WJ. PMID: 28964163; PMCID: PMC5570595.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    44. Rotors exhibit greater surface ECG variation during ventricular fibrillation than focal sources due to wavebreak, secondary rotors, and meander. J Cardiovasc Electrophysiol. 2017 Oct; 28(10):1158-1166. Ho G, Villongco CT, Yousefian O, Bradshaw A, Nguyen A, Faiwiszewski Y, Hayase J, Rappel WJ, McCulloch AD, Krummen DE. PMID: 28670858; PMCID: PMC7909714.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    45. Spatiotemporal Progression of Early Human Ventricular Fibrillation. JACC Clin Electrophysiol. 2017 12 11; 3(12):1437-1446. Vidmar D, Krummen DE, Hayase J, Narayan SM, Ho G, Rappel WJ. PMID: 29238755; PMCID: PMC5725953.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    46. Inferring single-cell behaviour from large-scale epithelial sheet migration patterns. J R Soc Interface. 2017 05; 14(130). Lee RM, Yue H, Rappel WJ, Losert W. PMID: 28490603; PMCID: PMC5454303.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    47. Mechanisms of Cell Polarization. Curr Opin Syst Biol. 2017 Jun; 3:43-53. Rappel WJ, Edelstein-Keshet L. PMID: 29038793; PMCID: PMC5640326.
      View in: PubMed   Mentions: 34  
    48. Two Independent Mapping Techniques Identify Rotational Activity Patterns at Sites of Local Termination During Persistent Atrial Fibrillation. J Cardiovasc Electrophysiol. 2017 Jun; 28(6):615-622. Alhusseini M, Vidmar D, Meckler GL, Kowalewski CA, Shenasa F, Wang PJ, Narayan SM, Rappel WJ. PMID: 28185348; PMCID: PMC5466451.
      View in: PubMed   Mentions: 27     Fields:    Translation:Humans
    49. Physical models of collective cell motility: from cell to tissue. J Phys D Appl Phys. 2017; 50(11). Camley BA, Rappel WJ. PMID: 28989187; PMCID: PMC5625300.
      View in: PubMed   Mentions: 52  
    50. Crawling and turning in a minimal reaction-diffusion cell motility model: Coupling cell shape and biochemistry. Phys Rev E. 2017 Jan; 95(1-1):012401. Camley BA, Zhao Y, Li B, Levine H, Rappel WJ. PMID: 28208438; PMCID: PMC5839343.
      View in: PubMed   Mentions: 26     Fields:    
    51. Modeling Contact Inhibition of Locomotion of Colliding Cells Migrating on Micropatterned Substrates. PLoS Comput Biol. 2016 12; 12(12):e1005239. Kulawiak DA, Camley BA, Rappel WJ. PMID: 27984579; PMCID: PMC5161303.
      View in: PubMed   Mentions: 17     Fields:    
    52. Determining conduction patterns on a sparse electrode grid: Implications for the analysis of clinical arrhythmias. Phys Rev E. 2016 Nov; 94(5-1):050401. Vidmar D, Narayan SM, Krummen DE, Rappel WJ. PMID: 27967050; PMCID: PMC5161037.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    53. Comparison of Detailed and Simplified Models of Human Atrial Myocytes to Recapitulate Patient Specific Properties. PLoS Comput Biol. 2016 08; 12(8):e1005060. Lombardo DM, Fenton FH, Narayan SM, Rappel WJ. PMID: 27494252; PMCID: PMC4975409.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansCells
    54. Collective Signal Processing in Cluster Chemotaxis: Roles of Adaptation, Amplification, and Co-attraction in Collective Guidance. PLoS Comput Biol. 2016 07; 12(7):e1005008. Camley BA, Zimmermann J, Levine H, Rappel WJ. PMID: 27367541; PMCID: PMC4930173.
      View in: PubMed   Mentions: 19     Fields:    Translation:Cells
    55. Emergent Collective Chemotaxis without Single-Cell Gradient Sensing. Phys Rev Lett. 2016 Mar 04; 116(9):098101. Camley BA, Zimmermann J, Levine H, Rappel WJ. PMID: 26991203; PMCID: PMC4885034.
      View in: PubMed   Mentions: 31     Fields:    
    56. Contact inhibition of locomotion determines cell-cell and cell-substrate forces in tissues. Proc Natl Acad Sci U S A. 2016 Mar 08; 113(10):2660-5. Zimmermann J, Camley BA, Rappel WJ, Levine H. PMID: 26903658; PMCID: PMC4791011.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansAnimalsCells
    57. Excitable waves and direction-sensing in Dictyostelium discoideum: steps towards a chemotaxis model. Phys Biol. 2016 Jan 29; 13(1):016002. Bhowmik A, Rappel WJ, Levine H. PMID: 26824302; PMCID: PMC4887094.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    58. Cell-cell communication during collective migration. Proc Natl Acad Sci U S A. 2016 Feb 09; 113(6):1471-3. Rappel WJ. PMID: 26802125; PMCID: PMC4760825.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    59. Reconstitution of CO2 Regulation of SLAC1 Anion Channel and Function of CO2-Permeable PIP2;1 Aquaporin as CARBONIC ANHYDRASE4 Interactor. Plant Cell. 2016 Feb; 28(2):568-82. Wang C, Hu H, Qin X, Zeise B, Xu D, Rappel WJ, Boron WF, Schroeder JI. PMID: 26764375; PMCID: PMC4790870.
      View in: PubMed   Mentions: 58     Fields:    Translation:AnimalsCells
    60. Phase synchrony reveals organization in human atrial fibrillation. Am J Physiol Heart Circ Physiol. 2015 Dec 15; 309(12):H2118-26. Vidmar D, Narayan SM, Rappel WJ. PMID: 26475585; PMCID: PMC4698428.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    61. CO2 Sensing and CO2 Regulation of Stomatal Conductance: Advances and Open Questions. Trends Plant Sci. 2016 Jan; 21(1):16-30. Engineer CB, Hashimoto-Sugimoto M, Negi J, Israelsson-Nordström M, Azoulay-Shemer T, Rappel WJ, Iba K, Schroeder JI. PMID: 26482956; PMCID: PMC4707055.
      View in: PubMed   Mentions: 79     Fields:    Translation:Cells
    62. Mechanisms for the Termination of Atrial Fibrillation by Localized Ablation: Computational and Clinical Studies. Circ Arrhythm Electrophysiol. 2015 Dec; 8(6):1325-33. Rappel WJ, Zaman JA, Narayan SM. PMID: 26359479; PMCID: PMC4764078.
      View in: PubMed   Mentions: 40     Fields:    Translation:Humans
    63. Modifying Ventricular Fibrillation by Targeted Rotor Substrate Ablation: Proof-of-Concept from Experimental Studies to Clinical VF. J Cardiovasc Electrophysiol. 2015 Oct; 26(10):1117-26. Krummen DE, Hayase J, Vampola SP, Ho G, Schricker AA, Lalani GG, Baykaner T, Coe TM, Clopton P, Rappel WJ, Omens JH, Narayan SM. PMID: 26179310; PMCID: PMC4826737.
      View in: PubMed   Mentions: 19     Fields:    Translation:Animals
    64. Distinct Cellular Locations of Carbonic Anhydrases Mediate Carbon Dioxide Control of Stomatal Movements. Plant Physiol. 2015 Oct; 169(2):1168-78. Hu H, Rappel WJ, Occhipinti R, Ries A, Böhmer M, You L, Xiao C, Engineer CB, Boron WF, Schroeder JI. PMID: 26243620; PMCID: PMC4587455.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimalsCells
    65. Structural contributions to fibrillatory rotors in a patient-derived computational model of the atria. Europace. 2014 Nov; 16 Suppl 4:iv3-iv10. Gonzales MJ, Vincent KP, Rappel WJ, Narayan SM, McCulloch AD. PMID: 25362167; PMCID: PMC4565557.
      View in: PubMed   Mentions: 41     Fields:    Translation:Humans
    66. Polarity mechanisms such as contact inhibition of locomotion regulate persistent rotational motion of mammalian cells on micropatterns. Proc Natl Acad Sci U S A. 2014 Oct 14; 111(41):14770-5. Camley BA, Zhang Y, Zhao Y, Li B, Ben-Jacob E, Levine H, Rappel WJ. PMID: 25258412; PMCID: PMC4205601.
      View in: PubMed   Mentions: 61     Fields:    Translation:Animals
    67. Cell substratum adhesion during early development of Dictyostelium discoideum. PLoS One. 2014; 9(9):e106574. Tarantola M, Bae A, Fuller D, Bodenschatz E, Rappel WJ, Loomis WF. PMID: 25247557; PMCID: PMC4172474.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    68. Cellular memory in eukaryotic chemotaxis. Proc Natl Acad Sci U S A. 2014 Oct 07; 111(40):14448-53. Skoge M, Yue H, Erickstad M, Bae A, Levine H, Groisman A, Loomis WF, Rappel WJ. PMID: 25249632; PMCID: PMC4210025.
      View in: PubMed   Mentions: 62     Fields:    Translation:Animals
    69. Human atrial fibrillation initiates via organized rather than disorganized mechanisms. Circ Arrhythm Electrophysiol. 2014 Oct; 7(5):816-24. Schricker AA, Lalani GG, Krummen DE, Rappel WJ, Narayan SM. PMID: 25217042; PMCID: PMC4206587.
      View in: PubMed   Mentions: 27     Fields:    Translation:Humans
    70. How input noise limits biochemical sensing in ultrasensitive systems. Phys Rev E Stat Nonlin Soft Matter Phys. 2014 Sep; 90(3):032702. Hu B, Rappel WJ, Levine H. PMID: 25314468; PMCID: PMC4457451.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    71. Intercellular stress reconstitution from traction force data. Biophys J. 2014 Aug 05; 107(3):548-554. Zimmermann J, Hayes RL, Basan M, Onuchic JN, Rappel WJ, Levine H. PMID: 25099794; PMCID: PMC4129476.
      View in: PubMed   Mentions: 21     Fields:    
    72. Modeling self-organized spatio-temporal patterns of PIP₃ and PTEN during spontaneous cell polarization. Phys Biol. 2014 Aug; 11(4):046002. Knoch F, Tarantola M, Bodenschatz E, Rappel WJ. PMID: 25024302; PMCID: PMC4526168.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    73. Velocity alignment leads to high persistence in confined cells. Phys Rev E Stat Nonlin Soft Matter Phys. 2014 Jun; 89(6):062705. Camley BA, Rappel WJ. PMID: 25019812; PMCID: PMC4458368.
      View in: PubMed   Mentions: 15     Fields:    
    74. Rotor stability separates sustained ventricular fibrillation from self-terminating episodes in humans. J Am Coll Cardiol. 2014 Jun 24; 63(24):2712-21. Krummen DE, Hayase J, Morris DJ, Ho J, Smetak MR, Clopton P, Rappel WJ, Narayan SM. PMID: 24794115; PMCID: PMC4396824.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    75. Periodic migration in a physical model of cells on micropatterns. Phys Rev Lett. 2013 Oct 11; 111(15):158102. Camley BA, Zhao Y, Li B, Levine H, Rappel WJ. PMID: 24160631; PMCID: PMC3855234.
      View in: PubMed   Mentions: 28     Fields:    Translation:Cells
    76. Theoretical considerations for mapping activation in human cardiac fibrillation. Chaos. 2013 Jun; 23(2):023113. Rappel WJ, Narayan SM. PMID: 23822478; PMCID: PMC3676373.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansAnimals
    77. A three-dimensional finite element model of human atrial anatomy: new methods for cubic Hermite meshes with extraordinary vertices. Med Image Anal. 2013 Jul; 17(5):525-37. Gonzales MJ, Sturgeon G, Krishnamurthy A, Hake J, Jonas R, Stark P, Rappel WJ, Narayan SM, Zhang Y, Segars WP, McCulloch AD. PMID: 23602918; PMCID: PMC3660421.
      View in: PubMed   Mentions: 32     Fields:    Translation:Humans
    78. Panoramic electrophysiological mapping but not electrogram morphology identifies stable sources for human atrial fibrillation: stable atrial fibrillation rotors and focal sources relate poorly to fractionated electrograms. Circ Arrhythm Electrophysiol. 2013 Feb; 6(1):58-67. Narayan SM, Shivkumar K, Krummen DE, Miller JM, Rappel WJ. PMID: 23392583; PMCID: PMC3746540.
      View in: PubMed   Mentions: 62     Fields:    Translation:Humans
    79. The physics of eukaryotic chemotaxis. Phys Today. 2013 Feb 01; 66(2). Levine H, Rappel WJ. PMID: 24363460; PMCID: PMC3867297.
      View in: PubMed   Mentions: 23  
    80. Alignment of cellular motility forces with tissue flow as a mechanism for efficient wound healing. Proc Natl Acad Sci U S A. 2013 Feb 12; 110(7):2452-9. Basan M, Elgeti J, Hannezo E, Rappel WJ, Levine H. PMID: 23345440; PMCID: PMC3574962.
      View in: PubMed   Mentions: 81     Fields:    Translation:Cells
    81. How input fluctuations reshape the dynamics of a biological switching system. Phys Rev E Stat Nonlin Soft Matter Phys. 2012 Dec; 86(6 Pt 1):061910. Hu B, Kessler DA, Rappel WJ, Levine H. PMID: 23367979; PMCID: PMC5836738.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    82. Computational mapping identifies localized mechanisms for ablation of atrial fibrillation. PLoS One. 2012; 7(9):e46034. Narayan SM, Krummen DE, Enyeart MW, Rappel WJ. PMID: 23049929; PMCID: PMC3458823.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansCTClinical Trials
    83. Innate non-specific cell substratum adhesion. PLoS One. 2012; 7(8):e42033. Loomis WF, Fuller D, Gutierrez E, Groisman A, Rappel WJ. PMID: 22952588; PMCID: PMC3432024.
      View in: PubMed   Mentions: 25     Fields:    Translation:Animals
    84. Treatment of atrial fibrillation by the ablation of localized sources: CONFIRM (Conventional Ablation for Atrial Fibrillation With or Without Focal Impulse and Rotor Modulation) trial. J Am Coll Cardiol. 2012 Aug 14; 60(7):628-36. Narayan SM, Krummen DE, Shivkumar K, Clopton P, Rappel WJ, Miller JM. PMID: 22818076; PMCID: PMC3416917.
      View in: PubMed   Mentions: 433     Fields:    Translation:HumansCTClinical Trials
    85. Clinical mapping approach to diagnose electrical rotors and focal impulse sources for human atrial fibrillation. J Cardiovasc Electrophysiol. 2012 May; 23(5):447-54. Narayan SM, Krummen DE, Rappel WJ. PMID: 22537106; PMCID: PMC3418865.
      View in: PubMed   Mentions: 128     Fields:    Translation:Humans
    86. Coupling actin flow, adhesion, and morphology in a computational cell motility model. Proc Natl Acad Sci U S A. 2012 May 01; 109(18):6851-6. Shao D, Levine H, Rappel WJ. PMID: 22493219; PMCID: PMC3344950.
      View in: PubMed   Mentions: 84     Fields:    Translation:AnimalsCells
    87. Adaptation in a eukaryotic pathway: combining experiments with modeling. Cell Cycle. 2012 Mar 15; 11(6):1051-2. Rappel WJ, Firtel RA. PMID: 22391206; PMCID: PMC3335914.
      View in: PubMed   Mentions: 3     Fields:    
    88. Noise effects in nonlinear biochemical signaling. Phys Rev E Stat Nonlin Soft Matter Phys. 2012 Jan; 85(1 Pt 1):011901. Bostani N, Kessler DA, Shnerb NM, Rappel WJ, Levine H. PMID: 22400585; PMCID: PMC4464780.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
    89. Incoherent feedforward control governs adaptation of activated ras in a eukaryotic chemotaxis pathway. Sci Signal. 2012 Jan 03; 5(205):ra2. Takeda K, Shao D, Adler M, Charest PG, Loomis WF, Levine H, Groisman A, Rappel WJ, Firtel RA. PMID: 22215733; PMCID: PMC3928814.
      View in: PubMed   Mentions: 87     Fields:    Translation:Animals
    90. Effects of input noise on a simple biochemical switch. Phys Rev Lett. 2011 Sep 30; 107(14):148101. Hu B, Kessler DA, Rappel WJ, Levine H. PMID: 22107236; PMCID: PMC4465233.
      View in: PubMed   Mentions: 6     Fields:    
    91. "Self-assisted" amoeboid navigation in complex environments. PLoS One. 2011; 6(8):e21955. Hecht I, Levine H, Rappel WJ, Ben-Jacob E. PMID: 21829602; PMCID: PMC3150345.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    92. Activated membrane patches guide chemotactic cell motility. PLoS Comput Biol. 2011 Jun; 7(6):e1002044. Hecht I, Skoge ML, Charest PG, Ben-Jacob E, Firtel RA, Loomis WF, Levine H, Rappel WJ. PMID: 21738453; PMCID: PMC3127810.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
    93. Quantifying information transmission in eukaryotic gradient sensing and chemotactic response. J Stat Phys. 2011 Apr 01; 142(6):1167-1186. Hu B, Chen W, Levine H, Rappel WJ. PMID: 21643513; PMCID: PMC3104692.
      View in: PubMed   Mentions: 6  
    94. How geometry and internal bias affect the accuracy of eukaryotic gradient sensing. Phys Rev E Stat Nonlin Soft Matter Phys. 2011 Feb; 83(2 Pt 1):021917. Hu B, Chen W, Rappel WJ, Levine H. PMID: 21405873; PMCID: PMC3120218.
      View in: PubMed   Mentions: 7     Fields:    Translation:Cells
    95. Design principles and specificity in biological networks with cross activation. Phys Biol. 2011 Apr; 8(2):026001. Hu B, Levine H, Rappel WJ. PMID: 21263168; PMCID: PMC5943036.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    96. Gradient sensing in defined chemotactic fields. Integr Biol (Camb). 2010 Nov; 2(11-12):659-68. Skoge M, Adler M, Groisman A, Levine H, Loomis WF, Rappel WJ. PMID: 20882228; PMCID: PMC3052262.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    97. Computational model for cell morphodynamics. Phys Rev Lett. 2010 Sep 03; 105(10):108104. Shao D, Rappel WJ, Levine H. PMID: 20867552; PMCID: PMC3048783.
      View in: PubMed   Mentions: 79     Fields:    
    98. Physical limits on cellular sensing of spatial gradients. Phys Rev Lett. 2010 Jul 23; 105(4):048104. Hu B, Chen W, Rappel WJ, Levine H. PMID: 20867888; PMCID: PMC3048844.
      View in: PubMed   Mentions: 38     Fields:    Translation:Cells
    99. The role of cell contraction and adhesion in dictyostelium motility. Biophys J. 2010 Jul 07; 99(1):50-8. Buenemann M, Levine H, Rappel WJ, Sander LM. PMID: 20655832; PMCID: PMC2895335.
      View in: PubMed   Mentions: 21     Fields:    Translation:Animals
    100. A comparison of deterministic and stochastic simulations of neuronal vesicle release models. Phys Biol. 2010 May 26; 7(2):026008. Modchang C, Nadkarni S, Bartol TM, Triampo W, Sejnowski TJ, Levine H, Rappel WJ. PMID: 20505227; PMCID: PMC2892017.
      View in: PubMed   Mentions: 14     Fields:    Translation:Cells
    101. External and internal constraints on eukaryotic chemotaxis. Proc Natl Acad Sci U S A. 2010 May 25; 107(21):9656-9. Fuller D, Chen W, Adler M, Groisman A, Levine H, Rappel WJ, Loomis WF. PMID: 20457897; PMCID: PMC2906906.
      View in: PubMed   Mentions: 62     Fields:    Translation:Animals
    102. Phenomenological approach to eukaryotic chemotactic efficiency. Phys Rev E Stat Nonlin Soft Matter Phys. 2010 Mar; 81(3 Pt 1):031906. Hu B, Fuller D, Loomis WF, Levine H, Rappel WJ. PMID: 20365769; PMCID: PMC2872938.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    103. Compartmentalization of second messengers in neurons: a mathematical analysis. Phys Rev E Stat Nonlin Soft Matter Phys. 2009 Oct; 80(4 Pt 1):041901. Chen W, Levine H, Rappel WJ. PMID: 19905336.
      View in: PubMed   Mentions: 10     Fields:    Translation:Cells
    104. Eukaryotic chemotaxis. Wiley Interdiscip Rev Syst Biol Med. 2009 Jul-Aug; 1(1):141-149. Rappel WJ, Loomis WF. PMID: 20648241; PMCID: PMC2906236.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    105. Mechanisms and constraints on yeast MAPK signaling specificity. Biophys J. 2009 Jun 17; 96(12):4755-63. Hu B, Rappel WJ, Levine H. PMID: 19527636; PMCID: PMC2712056.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    106. Determining the scale of the Bicoid morphogen gradient. Proc Natl Acad Sci U S A. 2009 Feb 10; 106(6):1710-5. Hecht I, Rappel WJ, Levine H. PMID: 19190186; PMCID: PMC2644102.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    107. A mathematical analysis of second messenger compartmentalization. Phys Biol. 2008 Dec 10; 5(4):046006. Chen W, Levine H, Rappel WJ. PMID: 19075354.
      View in: PubMed   Mentions: 15     Fields:    Translation:Cells
    108. Receptor noise limitations on chemotactic sensing. Proc Natl Acad Sci U S A. 2008 Dec 09; 105(49):19270-5. Rappel WJ, Levine H. PMID: 19064934; PMCID: PMC2614751.
      View in: PubMed   Mentions: 15     Fields:    Translation:Cells
    109. Repolarization and activation restitution near human pulmonary veins and atrial fibrillation initiation: a mechanism for the initiation of atrial fibrillation by premature beats. J Am Coll Cardiol. 2008 Oct 07; 52(15):1222-30. Narayan SM, Kazi D, Krummen DE, Rappel WJ. PMID: 18926325; PMCID: PMC2604131.
      View in: PubMed   Mentions: 67     Fields:    Translation:Humans
    110. Receptor noise and directional sensing in eukaryotic chemotaxis. Phys Rev Lett. 2008 Jun 06; 100(22):228101. Rappel WJ, Levine H. PMID: 18643461; PMCID: PMC2738688.
      View in: PubMed   Mentions: 21     Fields:    Translation:Cells
    111. Quantifying noise levels of intercellular signals. Phys Rev E Stat Nonlin Soft Matter Phys. 2007 Jun; 75(6 Pt 1):061905. Wang K, Rappel WJ, Kerr R, Levine H. PMID: 17677298.
      View in: PubMed   Mentions: 24     Fields:    Translation:Cells
    112. Flow photolysis for spatiotemporal stimulation of single cells. Anal Chem. 2007 May 15; 79(10):3940-4. Beta C, Wyatt D, Rappel WJ, Bodenschatz E. PMID: 17432827.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    113. Directional sensing in eukaryotic chemotaxis: a balanced inactivation model. Proc Natl Acad Sci U S A. 2006 Jun 27; 103(26):9761-6. Levine H, Kessler DA, Rappel WJ. PMID: 16782813; PMCID: PMC1502527.
      View in: PubMed   Mentions: 74     Fields:    Translation:AnimalsCells
    114. Embryonic pattern scaling achieved by oppositely directed morphogen gradients. Phys Biol. 2006 May 16; 3(2):107-20. McHale P, Rappel WJ, Levine H. PMID: 16829697.
      View in: PubMed   Mentions: 36     Fields:    Translation:Animals
    115. Dictyostelium discoideum chemotaxis: threshold for directed motion. Eur J Cell Biol. 2006 Sep; 85(9-10):981-9. Song L, Nadkarni SM, Bödeker HU, Beta C, Bae A, Franck C, Rappel WJ, Loomis WF, Bodenschatz E. PMID: 16529846.
      View in: PubMed   Mentions: 81     Fields:    Translation:Animals
    116. Division accuracy in a stochastic model of Min oscillations in Escherichia coli. Proc Natl Acad Sci U S A. 2006 Jan 10; 103(2):347-52. Kerr RA, Levine H, Sejnowski TJ, Rappel WJ. PMID: 16387859; PMCID: PMC1326155.
      View in: PubMed   Mentions: 37     Fields:    Translation:Cells
    117. Membrane-bound Turing patterns. Phys Rev E Stat Nonlin Soft Matter Phys. 2005 Dec; 72(6 Pt 1):061912. Levine H, Rappel WJ. PMID: 16485979.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    118. Excitation-contraction coupling gain and cooperativity of the cardiac ryanodine receptor: a modeling approach. Biophys J. 2005 Nov; 89(5):3017-25. Wang K, Tu Y, Rappel WJ, Levine H. PMID: 16126827; PMCID: PMC1366799.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    119. Dynamics of conduction blocks in a model of paced cardiac tissue. Phys Rev E Stat Nonlin Soft Matter Phys. 2005 May; 71(5 Pt 1):051911. Henry H, Rappel WJ. PMID: 16089575.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimals
    120. Modeling wave propagation in realistic heart geometries using the phase-field method. Chaos. 2005 Mar; 15(1):13502. Fenton FH, Cherry EM, Karma A, Rappel WJ. PMID: 15836267.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimals
    121. Emergent oscillations in unidirectionally coupled overdamped bistable systems. Phys Rev E Stat Nonlin Soft Matter Phys. 2004 Sep; 70(3 Pt 2):036103. Bulsara AR, In V, Kho A, Longhini P, Palacios A, Rappel WJ, Acebron J, Baglio S, Ando B. PMID: 15524583.
      View in: PubMed   Mentions:    Fields:    
    122. Cooperativity can reduce stochasticity in intracellular calcium dynamics. Phys Biol. 2004 Jun; 1(1-2):27-34. Wang K, Rappel WJ, Levine H. PMID: 16204819.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    123. The role of M cells and the long QT syndrome in cardiac arrhythmias: simulation studies of reentrant excitations using a detailed electrophysiological model. Chaos. 2004 Mar; 14(1):172-82. Henry H, Rappel WJ. PMID: 15003058.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    124. Noisy FitzHugh-Nagumo model: from single elements to globally coupled networks. Phys Rev E Stat Nonlin Soft Matter Phys. 2004 Feb; 69(2 Pt 2):026202. Acebrón JA, Bulsara AR, Rappel WJ. PMID: 14995543.
      View in: PubMed   Mentions: 2     Fields:    
    125. Computational approach for modeling intra- and extracellular dynamics. Phys Rev E Stat Nonlin Soft Matter Phys. 2003 Sep; 68(3 Pt 2):037702. Kockelkoren J, Levine H, Rappel WJ. PMID: 14524934.
      View in: PubMed   Mentions: 26     Fields:    
    126. Cooperative dynamics in a class of coupled two-dimensional oscillators. Phys Rev E Stat Nonlin Soft Matter Phys. 2003 Jan; 67(1 Pt 2):016210. Acebrón JA, Rappel WJ, Bulsara AR. PMID: 12636588.
      View in: PubMed   Mentions:    Fields:    
    127. Establishing direction during chemotaxis in eukaryotic cells. Biophys J. 2002 Sep; 83(3):1361-7. Rappel WJ, Thomas PJ, Levine H, Loomis WF. PMID: 12202361; PMCID: PMC1302234.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    128. Filament instability and rotational tissue anisotropy: A numerical study using detailed cardiac models. Chaos. 2001 Mar; 11(1):71-80. Rappel WJ. PMID: 12779442.
      View in: PubMed   Mentions: 13     Fields:    
    129. Self-organization in systems of self-propelled particles. Phys Rev E Stat Nonlin Soft Matter Phys. 2001 Jan; 63(1 Pt 2):017101. Levine H, Rappel WJ, Cohen I. PMID: 11304390.
      View in: PubMed   Mentions: 34     Fields:    Translation:Animals
    130. Cell-sorting in aggregates of Dictyostelium discoideum. J Cell Sci. 1999 Nov; 112 ( Pt 22):3923-9. Nicol A, Rappel W, Levine H, Loomis WF. PMID: 10547353.
      View in: PubMed   Mentions: 17     Fields:    Translation:Animals
    131. Phase-field model of dendritic sidebranching with thermal noise. Phys Rev E Stat Phys Plasmas Fluids Relat Interdiscip Topics. 1999 Oct; 60(4 Pt A):3614-25. Karma A, Rappel WJ. PMID: 11970195.
      View in: PubMed   Mentions: 13     Fields:    
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