James Covell

Title(s)Emeritus Professor, Medicine
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Collapse Research 
    Collapse Research Activities and Funding
    Molecular biology and mechanics of the cardiac interstitium
    NIH R01HL043617Jul 1, 1989 - Mar 31, 2013
    Role: Co-Principal Investigator
    Transmural Deformation
    NIH R01HL032583Jul 1, 1984 - Jun 30, 2010
    Role: Co-Principal Investigator
    Training in Cardiovascular Physiology and Pharmacology
    NIH T32HL007444Jul 1, 1979 - Jun 30, 2023
    Role: Co-Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    1. Low Intensity Epicardial Pacing During the Absolute Refractory Period Augments Left Ventricular Function Mediated by Local Catecholamine Release. J Cardiovasc Electrophysiol. 2016 09; 27(9):1102-9. Ito BR, Covell JW, Curtis GP. PMID: 27279561.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    2. Improvement in pump function with endocardial biventricular pacing increases with activation time at the left ventricular pacing site in failing canine hearts. Am J Physiol Heart Circ Physiol. 2011 Oct; 301(4):H1447-55. Howard EJ, Covell JW, Mulligan LJ, McCulloch AD, Omens JH, Kerckhoffs RC. PMID: 21784986; PMCID: PMC3197362.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    3. Tissue structure and ventricular wall mechanics. Circulation. 2008 Aug 12; 118(7):699-701. Covell JW. PMID: 18695201.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    4. Changes in regional myocardial volume during the cardiac cycle: implications for transmural blood flow and cardiac structure. Am J Physiol Heart Circ Physiol. 2008 Aug; 295(2):H610-8. Ashikaga H, Coppola BA, Yamazaki KG, Villarreal FJ, Omens JH, Covell JW. PMID: 18515651; PMCID: PMC2519196.
      View in: PubMed   Mentions: 9     Fields:    Translation:Animals
    5. Asynchrony of ventricular activation affects magnitude and timing of fiber stretch in late-activated regions of the canine heart. Am J Physiol Heart Circ Physiol. 2007 Jul; 293(1):H754-61. Coppola BA, Covell JW, McCulloch AD, Omens JH. PMID: 17449547; PMCID: PMC3328414.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    6. Myocardial protection in the failing heart: II. Effect of pulsatile cardioplegic perfusion under simulated left ventricular restoration. J Thorac Cardiovasc Surg. 2006 Oct; 132(4):884-90. Kassab GS, Kostelec M, Buckberg GD, Covell J, Sadeghi A, Hoffman JI. PMID: 17000301.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    7. Myocardial protection in the failing heart: I. Effect of cardioplegia and the beating state under simulated left ventricular restoration. J Thorac Cardiovasc Surg. 2006 Oct; 132(4):875-83. Kostelec M, Covell J, Buckberg GD, Sadeghi A, Hoffman JI, Kassab GS. PMID: 17000300.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    8. A role for decorin in the remodeling of myocardial infarction. Matrix Biol. 2005 Jun; 24(4):313-24. Weis SM, Zimmerman SD, Shah M, Covell JW, Omens JH, Ross J, Dalton N, Jones Y, Reed CC, Iozzo RV, McCulloch AD. PMID: 15949932.
      View in: PubMed   Mentions: 50     Fields:    Translation:Animals
    9. Diastolic dysfunction in volume-overload hypertrophy is associated with abnormal shearing of myolaminar sheets. Am J Physiol Heart Circ Physiol. 2005 Jun; 288(6):H2603-10. Ashikaga H, Covell JW, Omens JH. PMID: 15708954; PMCID: PMC2822838.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    10. Structure and mechanics of healing myocardial infarcts. Annu Rev Biomed Eng. 2005; 7:223-53. Holmes JW, Borg TK, Covell JW. PMID: 16004571.
      View in: PubMed   Mentions: 174     Fields:    Translation:HumansAnimals
    11. Abnormal cardiac wall motion and early matrix metalloproteinase activity. Am J Physiol Heart Circ Physiol. 2005 Mar; 288(3):H1080-7. García RA, Brown KL, Pavelec RS, Go KV, Covell JW, Villarreal FJ. PMID: 15486029.
      View in: PubMed   Mentions: 15     Fields:    Translation:Animals
    12. Importance of mitral valve second-order chordae for left ventricular geometry, wall thickening mechanics, and global systolic function. Circulation. 2004 Sep 14; 110(11 Suppl 1):II115-22. Rodriguez F, Langer F, Harrington KB, Tibayan FA, Zasio MK, Cheng A, Liang D, Daughters GT, Covell JW, Criscione JC, Ingels NB, Miller DC. PMID: 15364849.
      View in: PubMed   Mentions: 27     Fields:    Translation:Animals
    13. Remodeling in myocardium adjacent to an infarction in the pig left ventricle. Am J Physiol Heart Circ Physiol. 2004 Dec; 287(6):H2697-704. Zimmerman SD, Criscione J, Covell JW. PMID: 15319211.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    14. Time-dependent remodeling of transmural architecture underlying abnormal ventricular geometry in chronic volume overload heart failure. Am J Physiol Heart Circ Physiol. 2004 Nov; 287(5):H1994-2002. Ashikaga H, Omens JH, Covell JW. PMID: 15242833; PMCID: PMC2842928.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    15. Early degradation and serum appearance of type I collagen fragments after myocardial infarction. J Mol Cell Cardiol. 2004 Apr; 36(4):597-601. Villarreal F, Omens J, Dillmann W, Risteli J, Nguyen J, Covell J. PMID: 15081319.
      View in: PubMed   Mentions: 18     Fields:    Translation:Animals
    16. Transmural mechanics at left ventricular epicardial pacing site. Am J Physiol Heart Circ Physiol. 2004 Jun; 286(6):H2401-7. Ashikaga H, Omens JH, Ingels NB, Covell JW. PMID: 14751858; PMCID: PMC2965026.
      View in: PubMed   Mentions: 21     Fields:    Translation:Animals
    17. Transmural left ventricular mechanics underlying torsional recoil during relaxation. Am J Physiol Heart Circ Physiol. 2004 Feb; 286(2):H640-7. Ashikaga H, Criscione JC, Omens JH, Covell JW, Ingels NB. PMID: 14551052; PMCID: PMC2954110.
      View in: PubMed   Mentions: 52     Fields:    Translation:Animals
    18. Early short-term treatment with doxycycline modulates postinfarction left ventricular remodeling. Circulation. 2003 Sep 23; 108(12):1487-92. Villarreal FJ, Griffin M, Omens J, Dillmann W, Nguyen J, Covell J. PMID: 12952845.
      View in: PubMed   Mentions: 48     Fields:    Translation:AnimalsCells
    19. Contribution of laminar myofiber architecture to load-dependent changes in mechanics of LV myocardium. Am J Physiol Heart Circ Physiol. 2002 Apr; 282(4):H1510-20. Takayama Y, Costa KD, Covell JW. PMID: 11893589.
      View in: PubMed   Mentions: 38     Fields:    Translation:AnimalsCells
    20. Transmural distribution of three-dimensional systolic strains in stunned myocardium. Circulation. 2001 Jul 17; 104(3):336-41. Mazhari R, Omens JH, Pavelec RS, Covell JW, McCulloch AD. PMID: 11457754.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    21. Relating myocardial laminar architecture to shear strain and muscle fiber orientation. Am J Physiol Heart Circ Physiol. 2001 May; 280(5):H2222-9. Arts T, Costa KD, Covell JW, McCulloch AD. PMID: 11299225.
      View in: PubMed   Mentions: 44     Fields:    Translation:AnimalsCells
    22. Structural basis of regional dysfunction in acutely ischemic myocardium. Cardiovasc Res. 2000 Aug; 47(2):284-93. Mazhari R, Omens JH, Covell JW, McCulloch AD. PMID: 10946065.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    23. Regional dysfunction correlates with myofiber disarray in transgenic mice with ventricular expression of ras. Am J Physiol Heart Circ Physiol. 2000 Mar; 278(3):H898-906. Karlon WJ, McCulloch AD, Covell JW, Hunter JJ, Omens JH. PMID: 10710359; PMCID: PMC3328188.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    24. Structural and mechanical factors influencing infarct scar collagen organization. Am J Physiol Heart Circ Physiol. 2000 Jan; 278(1):H194-200. Zimmerman SD, Karlon WJ, Holmes JW, Omens JH, Covell JW. PMID: 10644599.
      View in: PubMed   Mentions: 18     Fields:    Translation:Animals
    25. Laminar fiber architecture and three-dimensional systolic mechanics in canine ventricular myocardium. Am J Physiol. 1999 02; 276(2):H595-607. Costa KD, Takayama Y, McCulloch AD, Covell JW. PMID: 9950861.
      View in: PubMed   Mentions: 106     Fields:    Translation:AnimalsCells
    26. Automated measurement of myofiber disarray in transgenic mice with ventricular expression of ras. Anat Rec. 1998 12; 252(4):612-25. Karlon WJ, Covell JW, McCulloch AD, Hunter JJ, Omens JH. PMID: 9845212.
      View in: PubMed   Mentions: 62     Fields:    Translation:AnimalsCells
    27. Protection against myocardial dysfunction after a brief ischemic period in transgenic mice expressing inducible heat shock protein 70. J Clin Invest. 1998 Feb 15; 101(4):855-62. Trost SU, Omens JH, Karlon WJ, Meyer M, Mestril R, Covell JW, Dillmann WH. PMID: 9466981; PMCID: PMC508634.
      View in: PubMed   Mentions: 29     Fields:    Translation:Animals
    28. Functional implications of myocardial scar structure. Am J Physiol. 1997 May; 272(5 Pt 2):H2123-30. Holmes JW, Nuñez JA, Covell JW. PMID: 9176277.
      View in: PubMed   Mentions: 49     Fields:    Translation:Animals
    29. Relationship between passive tissue strain and collagen uncoiling during healing of infarcted myocardium. Cardiovasc Res. 1997 Feb; 33(2):351-8. Omens JH, Miller TR, Covell JW. PMID: 9074699.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    30. Left ventricular perimysial collagen fibers uncoil rather than stretch during diastolic filling. Basic Res Cardiol. 1996 Mar-Apr; 91(2):111-22. MacKenna DA, Omens JH, Covell JW. PMID: 8740527.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    31. Enhanced regional deformation at the anterior papillary muscle insertion site after chordal transsection. Circulation. 1996 Feb 01; 93(3):585-93. Takayama Y, Holmes JW, LeGrice I, Covell JW. PMID: 8565179.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    32. Depressed regional deformation near anterior papillary muscle. Am J Physiol. 1995 Jul; 269(1 Pt 2):H262-70. Holmes JW, Takayama Y, LeGrice I, Covell JW. PMID: 7631856.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    33. Transverse shear along myocardial cleavage planes provides a mechanism for normal systolic wall thickening. Circ Res. 1995 Jul; 77(1):182-93. LeGrice IJ, Takayama Y, Covell JW. PMID: 7788876.
      View in: PubMed   Mentions: 80     Fields:    Translation:Animals
    34. Impaired subendocardial function in tachycardia-induced cardiac failure. Am J Physiol. 1995 May; 268(5 Pt 2):H1788-94. LeGrice IJ, Takayama Y, Holmes JW, Covell JW. PMID: 7771530.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    35. Effects of pressure overload on the passive mechanics of the rat left ventricle. Ann Biomed Eng. 1995 Mar-Apr; 23(2):152-63. Omens JH, Milkes DE, Covell JW. PMID: 7605052.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    36. Effect of coronary artery reperfusion on transmural myocardial remodeling in dogs. Circulation. 1995 Feb 15; 91(4):1143-53. Ono S, Waldman LK, Yamashita H, Covell JW, Ross J. PMID: 7850953.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    37. Gradients of epicardial strain across the perfusion boundary during acute myocardial ischemia. Am J Physiol. 1994 Dec; 267(6 Pt 2):H2348-62. Van Leuven SL, Waldman LK, McCulloch AD, Covell JW. PMID: 7810735.
      View in: PubMed   Mentions: 11     Fields:    Translation:Animals
    38. Scar remodeling and transmural deformation after infarction in the pig. Circulation. 1994 Jul; 90(1):411-20. Holmes JW, Yamashita H, Waldman LK, Covell JW. PMID: 8026026.
      View in: PubMed   Mentions: 33     Fields:    Translation:Animals
    39. Passive ventricular mechanics in tight-skin mice. Am J Physiol. 1994 Mar; 266(3 Pt 2):H1169-76. Omens JH, Rockman HA, Covell JW. PMID: 8160820.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    40. Contribution of collagen matrix to passive left ventricular mechanics in isolated rat hearts. Am J Physiol. 1994 Mar; 266(3 Pt 2):H1007-18. MacKenna DA, Omens JH, McCulloch AD, Covell JW. PMID: 8160804.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    41. Collagen characterization in volume-overload- and pressure-overload-induced cardiac hypertrophy in minipigs. Am J Physiol. 1993 Aug; 265(2 Pt 2):H434-8. Harper J, Harper E, Covell JW. PMID: 8368345.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    42. Transmural distribution of myocardial tissue growth induced by volume-overload hypertrophy in the dog. Circulation. 1991 Sep; 84(3):1235-45. Omens JH, Covell JW. PMID: 1832093.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    43. Skeletal muscle deformation in the lateral muscle of the intact rainbow trout Oncorhynchus mykiss during fast start maneuvers. J Exp Biol. 1991 Mar; 156:453-66. Covell JW, Smith M, Harper DG, Blake RW. PMID: 2051132.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    44. Transmural myocardial deformation in the ischemic canine left ventricle. Circ Res. 1991 Feb; 68(2):368-81. Villarreal FJ, Lew WY, Waldman LK, Covell JW. PMID: 1991344.
      View in: PubMed   Mentions: 25     Fields:    Translation:Animals
    45. Factors influencing diastolic function. Possible role of the extracellular matrix. Circulation. 1990 Feb; 81(2 Suppl):III155-8. Covell JW. PMID: 2297881.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    46. Relation between transmural deformation and local myofiber direction in canine left ventricle. Circ Res. 1988 Sep; 63(3):550-62. Waldman LK, Nosan D, Villarreal F, Covell JW. PMID: 3409487.
      View in: PubMed   Mentions: 62     Fields:    Translation:Animals
    47. Increase in cross-linking of type I and type III collagens associated with volume-overload hypertrophy. Circ Res. 1988 Aug; 63(2):399-408. Iimoto DS, Covell JW, Harper E. PMID: 2969308.
      View in: PubMed   Mentions: 24     Fields:    Translation:Animals
    48. Factors influencing late right ventricular ejection. Cardiovasc Res. 1988 Apr; 22(4):244-8. Raizada V, Sahn DJ, Covell JW. PMID: 3197054.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    49. Misrepresentation and responsibility in medical research. N Engl J Med. 1987 Nov 26; 317(22):1383-9. Engler RL, Covell JW, Friedman PJ, Kitcher PS, Peters RM. PMID: 3317039.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    50. Granulocytes cause reperfusion ventricular dysfunction after 15-minute ischemia in the dog. Circ Res. 1987 Jul; 61(1):20-8. Engler R, Covell JW. PMID: 3038366.
      View in: PubMed   Mentions: 31     Fields:    Translation:AnimalsCells
    51. Effects of ventricular pacing on finite deformation in canine left ventricles. Am J Physiol. 1987 May; 252(5 Pt 2):H1023-30. Waldman LK, Covell JW. PMID: 3578536.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    52. Transmural myocardial deformation in the canine left ventricle. Normal in vivo three-dimensional finite strains. Circ Res. 1985 Jul; 57(1):152-63. Waldman LK, Fung YC, Covell JW. PMID: 4006099.
      View in: PubMed   Mentions: 80     Fields:    Translation:Animals
    53. Mechanisms of augmented segment shortening in nonischemic areas during acute ischemia of the canine left ventricle. Circ Res. 1985 Mar; 56(3):351-8. Lew WY, Chen ZY, Guth B, Covell JW. PMID: 3971509.
      View in: PubMed   Mentions: 22     Fields:    Translation:Animals
    54. Relationship between myocardial fiber direction and segment shortening in the midwall of the canine left ventricle. Circ Res. 1985 Jan; 56(1):31-9. Freeman GL, LeWinter MM, Engler RL, Covell JW. PMID: 3967346.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    55. Relationship between ejection phase indices of performance and myocardial functions during the development of pressure overload hypertrophy. Am Heart J. 1984 Apr; 107(4):738-44. Hoffman H, Covell JW. PMID: 6230908.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    56. Regional venous return: nitroprusside effect in normal and chronically congested dogs. Am J Physiol. 1983 Nov; 245(5 Pt 1):H814-23. Engler RL, Freeman GL, Covell JW. PMID: 6605693.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    57. Changes in plasma renin activity and haemodynamics during vasodilator therapy in conscious dogs with myocardial infarction or chronic volume overload. Eur J Clin Invest. 1983 Aug; 13(4):331-8. Pouleur H, Engler RL, Link J, Printz MP, Covell JW. PMID: 6413220.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    58. Local auxotonic systolic force and work in canine right ventricular free wall. Am J Physiol. 1983 Feb; 244(2):H186-93. Piene H, Covell JW. PMID: 6824090.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    59. Changes in control of renin release in congestive heart failure in dogs: response to acute and chronic vasodilator therapy. Clin Exp Hypertens A. 1982; 4(4-5):639-59. Engler R, Pouleur H, Link J, Printz M, Covell JW. PMID: 7049441.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    60. Determinants of myocardial hemorrhage after coronary reperfusion in the anesthetized dog. Circulation. 1982 Jan; 65(1):62-9. Higginson LA, White F, Heggtveit HA, Sanders TM, Bloor CM, Covell JW. PMID: 7053289.
      View in: PubMed   Mentions: 25     Fields:    Translation:Animals
    61. Reflex sympathetic augmentation of left-ventricular inotropic state in the conscious dog. Am J Physiol. 1981 Dec; 241(6):H857-63. Yoran C, Higginson L, Romero MA, Covell JW, Ross J. PMID: 7325254.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    62. Effects of experimental volume-overload hypertrophy on myocardial blood flow and cardiac function. Am J Physiol. 1981 Oct; 241(4):H564-70. Badke FR, White FC, Le Winter M, Covell J, Andres J, Bloor C. PMID: 6459033.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    63. Effect of myocardial infarction on high-frequency QRS potentials. Circulation. 1981 Jul; 64(1):34-42. Goldberger AL, Bhargava V, Froelicher V, Covell J. PMID: 7237722.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    64. A force-length-time relationship describes the mechanics of canine left ventricular wall segments during auxotonic contractions. Circ Res. 1981 Jul; 49(1):70-9. Piene H, Covell JW. PMID: 7237702.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    65. The role of the right heart in acute cardiac tamponade in dogs. Circ Res. 1981 May; 48(5):701-10. Ditchey R, Engler R, LeWinter M, Pavelec R, Bhargava V, Covell J, Moores W, Shabetai R. PMID: 7214678.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    66. The creatine kinase curve area and peak creatine kinase after acute myocardial infarction: usefulness and limitations. Am Heart J. 1981 Feb; 101(2):162-8. Ryan W, Karliner JS, Gilpin EA, Covell JW, DeLuca M, Ross J. PMID: 7468417.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    67. Effects of ventricular pacing on regional left ventricular performance in the dog. Am J Physiol. 1980 Jun; 238(6):H858-67. Badke FR, Boinay P, Covell JW. PMID: 7386645.
      View in: PubMed   Mentions: 39     Fields:    Translation:Animals
    68. Left ventricular wall stress and aortic input impedance. Fed Proc. 1980 Feb; 39(2):202-7. Covell JW, Pouleur H, Ross J. PMID: 7353678.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    69. Effects of nitroprusside on venous return and central blood volume in the absence and presence of acute heart failure. Circulation. 1980 Feb; 61(2):328-37. Pouleur H, Covell JW, Ross J. PMID: 7351058.
      View in: PubMed   Mentions: 16     Fields:    Translation:Animals
    70. Time-course of "redistribution" of thallium-201 administered during transient ischemia. Eur J Nucl Med. 1979 Oct; 4(5):351-8. Schelbert HR, Schuler G, Ashburn WL, Covell JW. PMID: 520343.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    71. Diastolic viscous properties of the intact canine left ventricle. Circ Res. 1979 Sep; 45(3):410-9. Pouleur H, Karliner JS, LeWinter MM, Covell JW. PMID: 455608.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    72. Early changes in left ventricular regional dimensions and function during chronic volume overloading in the conscious dog. Circ Res. 1979 Sep; 45(3):420-8. Badke FR, Covell JW. PMID: 455609.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    73. Effects of alterations in aortic input impedance on the force-velocity-length relationship in the intact canine heart. Circ Res. 1979 Jul; 45(1):126-36. Pouleur H, Covell JW, Ross J. PMID: 445694.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    74. Prognosis after acute myocardial infarction: a multivariate analysis of mortality and survival. Circulation. 1979 Jun; 59(6):1124-36. Henning H, Gilpin EA, Covell JW, Swan EA, O'Rourke RA, Ross J. PMID: 436204.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    75. Fiber orientation in hypertrophied canine left ventricle. Am J Physiol. 1979 Mar; 236(3):H487-93. Carew TE, Covell JW. PMID: 154847.
      View in: PubMed   Mentions: 9     Fields:    Translation:Animals
    76. Alteration in heart rate response to hemorrhage in conscious dogs with volume overload. Am J Physiol. 1978 Oct; 235(4):H422-8. LeWinter MM, Karliner JS, Covell JW. PMID: 696883.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    77. Left ventricular function in exercise-induced hypertrophy in dogs. Am J Cardiol. 1978 Jul; 42(1):82-8. Carew TE, Covell JW. PMID: 150223.
      View in: PubMed   Mentions: 9     Fields:    Translation:Animals
    78. Comparison of left ventricular free wall and septal diastolic compliance in the dog. Am J Physiol. 1978 Apr; 234(4):H392-8. Kent RS, Carew TE, LeWinter MM, Covell JW. PMID: 645877.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    79. Regional myocardial function and dimensions early and late after myocardial infarction in the unanesthetized dog. Circ Res. 1977 Feb; 40(2):158-65. Theroux P, Ross J, Franklin D, Covell JW, Bloor CM, Sasayama S. PMID: 844142.
      View in: PubMed   Mentions: 24     Fields:    Translation:Animals
    80. Regional shortening patterns in canine right ventricle. Am J Physiol. 1976 Nov; 231(5 Pt. 1):1395-1400. Raines RA, LeWinter MM, Covell JW. PMID: 998782.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    81. A comparison of the active stiffness of fetal and adult cardiac muscle. Pediatr Res. 1976 Jul; 10(7):660-4. McPherson RA, Kramer MF, Covell JW, Friedman WF. PMID: 934732.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    82. Effects of heparin in large doses on the extent of myocardial ischemia after acute coronary occlusion in the dog. Am J Cardiol. 1976 Mar 31; 37(4):599-604. Saliba MJ, Covell JW, Bloor CM. PMID: 1258797.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    83. Effect of intramyocardial pressure on the phasic flow in the intraventricular septal artery. Cardiovasc Res. 1976 Jan; 10(1):56-64. Carew TE, Covell JW. PMID: 130207.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    84. Cardiac norepinephrine stores and chronotropic reflex response after thoracotomy. J Appl Physiol. 1975 Aug; 39(2):287-91. Schelbert HR, Pavelec RS, Sandoval S, Covell JW. PMID: 809409.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    85. Regional differences in myocardial performance in the left ventricle of the dog. Circ Res. 1975 Aug; 37(2):191-9. LeWinter MM, Kent RS, Kroener JM, Carew TE, Covell JW. PMID: 1149193.
      View in: PubMed   Mentions: 28     Fields:    Translation:Animals
    86. Systolic pressure--diameter relations in the normal conscious dog. Cardiovasc Res. 1975 Jul; 9(4):447-55. Mahler F, Covell JW, Ross J. PMID: 1182720.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    87. Series elasticity in the intact heart. Evidence for the application of the Hill model for muscle to the intact left ventricle. Pflugers Arch. 1975 Jun 26; 357(3-4):225-36. Covell JW, Taylor RR, Sonnenblick EH, Ross J. PMID: 1238987.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    88. Effects of changes in preload, afterload and inotropic state on ejection and isovolumic phase measures of contractility in the conscious dog. Am J Cardiol. 1975 May; 35(5):626-34. Mahler F, Ross J, O'Rourke RA, Covell JW. PMID: 1124716.
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    89. Altered myocardial oxygen consumption after coronary occlusion in anesthetized dogs. Am Heart J. 1975 Mar; 89(3):333-7. Ramakrishna NC, Sobel BE, Shell WE, Covell JW. PMID: 1114962.
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    90. Relations between afterload, stroke volume, and descending limb of Starling's curve. Am J Physiol. 1974 Oct; 227(4):884-90. MacGregor DC, Covell JW, Mahler F, Dilley RB, Ross J. PMID: 4279559.
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    91. Coronary collateral flow following acute coronary occlusion: a diastolic phenomenon. Cardiovasc Res. 1974 Sep; 8(5):621-31. Brown BG, Gundel WD, Gott VL, Covell JW. PMID: 4215562.
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    92. Factors influencing indices of left ventricle contractility in the conscious dog. Cardiovasc Res. 1974 May; 8(3):299-312. Davidson DM, Covell JW, Malloch CI, Ross J. PMID: 4413423.
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    93. Contractile responses of the left ventricle to acute and chronic stress. Eur J Cardiol. 1974 Mar; 1(3):325-32. Ross J, Covell JW, Mahler F. PMID: 4442437.
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    94. Early estimation of myocardial damage in conscious dogs and patients with evolving acute myocardial infarction. J Clin Invest. 1973 Oct; 52(10):2579-90. Shell WE, Lavelle JF, Covell JW, Sobel BE. PMID: 4729051; PMCID: PMC302518.
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    95. Nature and significance of alterations in myocardial compliance. Am J Cardiol. 1973 Sep 20; 32(4):449-55. Covell JW, Ross J. PMID: 4269700.
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    96. A new technique for the continuous assessment of fetal and neonatal cardiac performance. Am J Obstet Gynecol. 1973 Aug 01; 116(7):963-72. Kirkpatrick SE, Covell JW, Friedman WF. PMID: 4718223.
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    97. Rapid fixation of the left ventricle: continuous angiographic and dynamic recordings. J Appl Physiol. 1973 Jul; 35(1):155-7. Yoran C, Covell JW, Ross J. PMID: 4197708.
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    98. Mechanics of isotonic left ventricular contractions. Am J Physiol. 1973 Apr; 224(4):725-32. Burns JW, Covell JW, Ross J. PMID: 4698789.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    99. A technique for processing coronary hemodynamic data with a small hybrid computing system. Comput Biol Med. 1973 Apr; 3(1):47-54. Lavelle JF, Bloor CM, Covell JW. PMID: 4724228.
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    100. Effect of practolol on the extent of myocardial ischaemic injury after experimental coronary occlusion and its effects of ventricular function in the normal and ischaemic heart. Cardiovasc Res. 1973 Mar; 7(2):167-73. Libby P, Maroko PR, Covell JW, Malloch CI, Ross J, Braunwald E. PMID: 4144351.
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    101. Structural basis for the ascending limb of left ventricular function. Circ Res. 1973 Feb; 32(2):297-303. Yoran C, Covell JW, Ross J. PMID: 4685973.
      View in: PubMed   Mentions: 17     Fields:    Translation:Animals
    102. Myocardial oxygen consumption during isotonic and isolumic contractions in the intact heart. Am J Physiol. 1972 Dec; 223(6):1491-7. Burns JW, Covell JW. PMID: 4641642.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    103. Contractile performance of the hypertrophied and chronically failing cat ventricle. Am J Physiol. 1972 Nov; 223(5):1150-7. Spann JF, Covell JW, Eckberg DL, Sonnenblick EH, Ross J, Braunwald E. PMID: 4265953.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    104. Coronary artery reperfusion. II. Reduction of myocardial infarct size at 1 week after the coronary occlusion. J Clin Invest. 1972 Oct; 51(10):2717-23. Ginks WR, Sybers HD, Maroko PR, Covell JW, Sobel BE, Ross J. PMID: 5056664; PMCID: PMC332972.
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    105. Effects of increased arterial pressure and positive inotropic agents on the severity of myocardial ischemia in the acutely depressed heart. Am J Cardiol. 1972 Sep; 30(4):371-7. Watanabe T, Covell JW, Maroko PR, Braunwald E, Ross J. PMID: 5056848.
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    106. Effects of intraaortic balloon counterpulsation on the severity of myocardial ischemic injury following acute coronary occlusion. Counterpulsation and myocardial injury. Circulation. 1972 Jun; 45(6):1150-9. Maroko PR, Bernstein EF, Libby P, DeLaria GA, Covell JW, Ross J, Braunwald E. PMID: 5032815.
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    107. Effect of glucose-insulin-potassium infusion on myocardial infarction following experimental coronary artery occlusion. Circulation. 1972 Jun; 45(6):1160-75. Maroko PR, Libby P, Sobel BE, Bloor CM, Sybers HD, Shell WE, Covell JW, Braunwald E. PMID: 5032816.
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    108. A comparison of pressure-volume relations of the fetal, newborn, and adult heart. Am J Physiol. 1972 May; 222(5):1285-90. Romero T, Covell J, Friedman WF. PMID: 5022387.
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    109. Left ventricular dilatation and diastolic compliance changes during chronic volume overloading. Circulation. 1972 May; 45(5):943-51. McCullagh WH, Covell JW, Ross J. PMID: 5020808.
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    110. Precordial S-T segment elevation mapping: an atraumatic method for assessing alterations in the extent of myocardial ischemic injury. The effects of pharmacologic and hemodynamic interventions. Am J Cardiol. 1972 Feb; 29(2):223-30. Maroko PR, Libby P, Covell JW, Sobel BE, Ross J, Braunwald E. PMID: 5058350.
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    111. Mechanical performance and efficiency of the left ventricle during ventricular stimulation. Am J Physiol. 1971 Dec; 221(6):1686-91. Boerth RC, Covell JW. PMID: 5124311.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    112. Feasibility and hazards of the intracoronary injection of radioactive serum albumin macroaggregates for external myocardial perfusion imaging. Invest Radiol. 1971 Nov-Dec; 6(6):379-87. Schelbert HR, Ashburn WL, Covell JW, Simon AL, Braunwald E, Ross J. PMID: 5162481.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    113. Observations on factors affecting local forces in the left ventricular wall during acute myocardial ischemia. Circ Res. 1971 Sep; 29(3):306-16. Schelbert HR, Covell JW, Burns JW, Maroko PR, Ross J. PMID: 5093290.
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    114. Assessment of cardiac contractility. The relation between the rate of pressure rise and ventricular pressure during isovolumic systole. Circulation. 1971 Jul; 44(1):47-58. Mason DT, Braunwald E, Covell JW, Sonnenblick EH, Ross J. PMID: 5561416.
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    115. Comparison of directly measured left ventricular wall stress and stress calculated from geometric reference figures. Circ Res. 1971 Jun; 28(6):611-21. Burns JW, Covell JW, Myers R, Ross J. PMID: 5087324.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    116. Congestive heart failure following chronic tachycardia. Am Heart J. 1971 Jun; 81(6):790-8. Coleman HN, Taylor RR, Pool PE, Whipple GH, Covell JW, Ross J, Braunwald E. PMID: 5088355.
      View in: PubMed   Mentions: 32     Fields:    Translation:Animals
    117. Diastolic geometry and sarcomere lengths in the chronically dilated canine left ventricle. Circ Res. 1971 Jan; 28(1):49-61. Ross J, Sonnenblick EH, Taylor RR, Spotnitz HM, Covell JW. PMID: 5539440.
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    118. Factors influencing infarct size following experimental coronary artery occlusions. Circulation. 1971 Jan; 43(1):67-82. Maroko PR, Kjekshus JK, Sobel BE, Watanabe T, Covell JW, Ross J, Braunwald E. PMID: 5540853.
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    119. Left ventricular performance following correction of free aortic regurgitation. Circulation. 1970 Nov; 42(5):773-80. Gault JH, Covell JW, Braunwald E, Ross J. PMID: 5477250.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    120. Left ventricular mechanics and oxygen consumption during arterial counterpulsation. Am J Physiol. 1969 Nov; 217(5):1352-8. Spotnitz HM, Covell JW, Ross J, Braunwald E. PMID: 5346299.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    121. Production of isotonic contractions in the intact canine left ventricle. J Appl Physiol. 1969 Oct; 27(4):577-81. Covell JW, Fuhrer JS, Boerth RC, Ross J. PMID: 5822570.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    122. Volume-tension diagrams of ejecting and isovolumic contractions in left ventricle. Am J Physiol. 1969 May; 216(5):1097-102. Taylor RR, Covell JW, Ross J. PMID: 5797292.
      View in: PubMed   Mentions: 9     Fields:    Translation:Animals
    123. High-energy phosphate concentrations in dog myocardium during stress. Am J Physiol. 1969 May; 216(5):1103-6. Boerth RC, Covell JW, Seagren SC, Pool PE. PMID: 5768058.
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    124. Increased myocardial oxygen consumption and contractile state associated with increased heart rate in dogs. Circ Res. 1969 May; 24(5):725-34. Boerth RC, Covell JW, Pool PE, Ross J. PMID: 5770259.
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    125. Influence of the thyroid state on left ventricular tension-velocity relations in the intact, sedated dog. J Clin Invest. 1969 Apr; 48(4):775-84. Taylor RR, Covell JW, Ross J. PMID: 5774113; PMCID: PMC322282.
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    126. Effects of acute valvular regurgitation on the oxygen consumption of the canine heart. Circ Res. 1968 Jul; 23(1):33-43. Urschel CW, Covell JW, Graham TP, Clancy RL, Ross J, Sonnenblick EH, Braunwald E. PMID: 5661937.
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    127. Left ventricular function in experimental aorto-caval fistula with circulatory congestion and fluid retention. J Clin Invest. 1968 Jun; 47(6):1333-42. Taylor RR, Covell JW, Ross J. PMID: 5653213; PMCID: PMC297289.
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    128. A biopsy drill permitting rapid freezing. J Appl Physiol. 1968 Jun; 24(6):832-3. Pool PE, Norris GF, Lewis RM, Covell JW. PMID: 5653170.
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    129. Relative importance of the carotid and aortic baroreceptors in the reflex control of heart rate. Am J Physiol. 1968 May; 214(5):955-61. Glick G, Covell JW. PMID: 4967417.
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    130. Myocardial mechanics in aortic and mitral valvular regurgitation: the concept of instantaneous impedance as a determinant of the performance of the intact heart. J Clin Invest. 1968 Apr; 47(4):867-83. Urschel CW, Covell JW, Sonnenblick EH, Ross J, Braunwald E. PMID: 5641623; PMCID: PMC297236.
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    131. Control of myocardial oxygen consumption: relative influence of contractile state and tension development. J Clin Invest. 1968 Feb; 47(2):375-85. Graham TP, Covell JW, Sonnenblick EH, Ross J, Braunwald E. PMID: 12066781; PMCID: PMC297180.
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    132. Effects of decreased aortic compliance on performance of the left ventricle. Am J Physiol. 1968 Feb; 214(2):298-304. Urschel CW, Covell JW, Sonnenblick EH, Ross J, Braunwald E. PMID: 5635873.
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    133. The ultrastructure of the heart in systole and diastole. Chantes in sarcomere length. Circ Res. 1967 Oct; 21(4):423-31. Sonnenblick EH, Ross J, Covell JW, Spotnitz HM, Spiro D. PMID: 6057700.
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    134. The architecture of the heart in systole and diastole. Technique of rapid fixation and analysis of left ventricular geometry. Circ Res. 1967 Oct; 21(4):409-21. Ross J, Sonnenblick EH, Covell JW, Kaiser G, Spiro D. PMID: 6057699.
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    135. Dependence of ventricular distensibility on filling of the opposite ventricle. Am J Physiol. 1967 Sep; 213(3):711-8. Taylor RR, Covell JW, Sonnenblick EH, Ross J. PMID: 6036789.
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    136. Effects of serotonin on the contractile state of the myocardium. Am J Physiol. 1967 Aug; 213(2):483-6. Buccino RA, Covell JW, Sonnenblick EH, Braunwald E. PMID: 6036336.
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    137. Myocardial oxygen consumption in acute experimental cardiac depression. Circ Res. 1967 Aug; 21(2):123-38. Graham TP, Ross J, Covell JW, Sonnenblick EH, Clancy RL. PMID: 4157323.
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    138. A quantitative analysis of left ventricular myocardial function in the intact, sedated dog. Circ Res. 1967 Jul; 21(1):99-115. Taylor RR, Ross J, Covell JW, Sonnenblick EH. PMID: 6028859.
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    139. Reduction of cardiac tyrosine hydroxylase activity in experimental congestive heart failure. Its role in the depletion of cardiac norepinephrine stores. Circ Res. 1967 Mar; 20(3):349-53. Pool PE, Covell JW, Levitt M, Gibb J, Braunwald E. PMID: 6025614.
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    140. The mechanics of left ventricular contraction in acute experimental cardiac failure. J Clin Invest. 1967 Mar; 46(3):299-312. Ross J, Covell JW, Sonnenblick EH. PMID: 4381563; PMCID: PMC297051.
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    141. Effects of increasing frequency of contraction on the force velocity relation of left ventricle. Cardiovasc Res. 1967 Jan; 1(1):2-8. Covell JW, Ross J, Taylor R, Sonnenblick EH, Braunwald E. PMID: 6060158.
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    142. Effects of acutely induced ischemic heart failure on myocardial high energy phosphate stores. Proc Soc Exp Biol Med. 1967 Jan; 124(1):126-31. Covell JW, Pool PE, Braunwald E. PMID: 6017755.
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    143. Alterations in resting length-tension relations of cardiac muscle induced by changes in contractile force. Circ Res. 1966 Nov; 19(5):980-8. Sonnenblick EH, Ross J, Covell JW, Braunwald E. PMID: 5954130.
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    144. Studies on digitalis. XVI. Effects on myocardial oxygen consumption. J Clin Invest. 1966 Oct; 45(10):1535-42. Covell JW, Braunwald E, Ross J, Sonnenblick EH. PMID: 5925512; PMCID: PMC292835.
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    145. Comparison of the force-velocity relation and the ventricular function curve as measures of the contractile state of the intact heart. Circ Res. 1966 Aug; 19(2):364-72. Covell JW, Ross J, Sonnenblick EH, Braunwald E. PMID: 5914848.
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    146. Myocardial high energy phosphate stores in acutely induced hypoxic heart failure. Circ Res. 1966 Aug; 19(2):221-9. Pool PE, Covell JW, Chidsey CA, Braunwald E. PMID: 5914842.
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    147. Congestive heart failure. Biochemical and physiological considerations. Combined clinical staff conference at the National Institutes of Health. Ann Intern Med. 1966 Apr; 64(4):904-41. Braunwald E, Chidsey CA, Pool PE, Sonnenblick EH, Ross J, Mason DT, Spann JF, Covell JW. PMID: 23841211.
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    148. Velocity of contraction as a determinant of myocardial oxygen consumption. Am J Physiol. 1965 Nov; 209(5):919-27. Sonnenblick EH, Ross J, Covell JW, Kaiser GA, Braunwald E. PMID: 5849492.
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