Erica Saphire

Title(s)Adjunct Professor, Medicine
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Collapse Research 
    Collapse Research Activities and Funding
    Consortium for Immunotherapeutics against Emerging Viral Threats
    NIH U19AI142790May 1, 2019 - Apr 30, 2024
    Role: Principal Investigator
    Rationally Designed Pan-Ebolavirus Vaccine
    NIH R01AI132204Jun 20, 2017 - May 31, 2022
    Role: Co-Principal Investigator
    Function and assembly of the Ebola virus nucleocapsid
    NIH R01AI118016Mar 1, 2016 - Aug 31, 2020
    Role: Principal Investigator
    Function and assembly of the Ebola virus nucleocapsid
    NIH R56AI118016Mar 1, 2015 - Feb 29, 2016
    Role: Principal Investigator
    Interpreting a hard-won structure of the arenavirus prefusion glycoprotein
    NIH R21AI116112Dec 1, 2014 - Nov 30, 2017
    Role: Principal Investigator
    Consortium for Immunotherapeutics Against Viral Hemorrhagic Fevers
    NIH U19AI109762Mar 15, 2014 - Jun 28, 2019
    Role: Principal Investigator
    Analysis of immunotherapeutics to native Marburg virus epitopes
    NIH R01AI089498Jul 1, 2010 - Dec 31, 2015
    Role: Principal Investigator
    STRUCTURE DRIVEN ANALYSIS OF EBOLA VIRUS RECEPTOR BINDING SITE
    NIH R01AI081982Dec 15, 2009 - May 31, 2015
    Role: Principal Investigator
    Immunotherapeutics against Marburg: Development, structural &functional anaylsis
    NIH U01AI082156Sep 1, 2009 - Aug 31, 2011
    Role: Principal Investigator
    Immunotherapeutics vs Ebola Sudan: Development, Structural &Functional Analysis
    NIH U01AI070530Sep 15, 2006 - Aug 31, 2011
    Role: Principal Investigator
    EBOLA VIRAL GLYCOPROTEINS: STRUCTURAL ANALYSIS
    NIH R01AI067927Jul 15, 2006 - Jun 30, 2014
    Role: Principal Investigator
    Structural Studies of Ebola Viral Pathogenesis
    NIH R21AI053423Sep 15, 2002 - Aug 31, 2004
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Structure of the rabies virus glycoprotein trimer bound to a prefusion-specific neutralizing antibody. Sci Adv. 2022 Jun 17; 8(24):eabp9151. Callaway HM, Zyla D, Larrous F, de Melo GD, Hastie KM, Avalos RD, Agarwal A, Corti D, Bourhy H, Saphire EO. PMID: 35714192.
      View in: PubMed   Mentions:
    2. Delineating the mechanism of anti-Lassa virus GPC-A neutralizing antibodies. Cell Rep. 2022 May 24; 39(8):110841. Enriquez AS, Buck TK, Li H, Norris MJ, Moon-Walker A, Zandonatti MA, Harkins SS, Robinson JE, Branco LM, Garry RF, Saphire EO, Hastie KM. PMID: 35613585.
      View in: PubMed   Mentions:
    3. mRNA-1273 and BNT162b2 COVID-19 vaccines elicit antibodies with differences in Fc-mediated effector functions. Sci Transl Med. 2022 May 18; 14(645):eabm2311. Kaplonek P, Cizmeci D, Fischinger S, Collier AR, Suscovich T, Linde C, Broge T, Mann C, Amanat F, Dayal D, Rhee J, de St Aubin M, Nilles EJ, Musk ER, Menon AS, Saphire EO, Krammer F, Lauffenburger DA, Barouch DH, Alter G. PMID: 35348368; PMCID: PMC8995030.
      View in: PubMed   Mentions:
    4. Inducing broad-based immunity against viruses with pandemic potential. Immunity. 2022 05 10; 55(5):738-748. Sette A, Saphire EO. PMID: 35545026.
      View in: PubMed   Mentions:
    5. Functional interactomes of the Ebola virus polymerase identified by proximity proteomics in the context of viral replication. Cell Rep. 2022 03 22; 38(12):110544. Fang J, Pietzsch C, Tsaprailis G, Crynen G, Cho KF, Ting AY, Bukreyev A, de la Torre JC, Saphire EO. PMID: 35320713.
      View in: PubMed   Mentions:
    6. Development and Structural Analysis of Antibody Therapeutics for Filoviruses. Pathogens. 2022 Mar 18; 11(3). Yu X, Saphire EO. PMID: 35335698; PMCID: PMC8949092.
      View in: PubMed   Mentions:
    7. Asymmetric and non-stoichiometric glycoprotein recognition by two distinct antibodies results in broad protection against ebolaviruses. Cell. 2022 03 17; 185(6):995-1007.e18. Milligan JC, Davis CW, Yu X, Ilinykh PA, Huang K, Halfmann PJ, Cross RW, Borisevich V, Agans KN, Geisbert JB, Chennareddy C, Goff AJ, Piper AE, Hui S, Shaffer KCL, Buck T, Heinrich ML, Branco LM, Crozier I, Holbrook MR, Kuhn JH, Kawaoka Y, Glass PJ, Bukreyev A, Geisbert TW, Worwa G, Ahmed R, Saphire EO. PMID: 35303429.
      View in: PubMed   Mentions:
    8. Stopping pandemics before they start: Lessons learned from SARS-CoV-2. Science. 2022 Mar 11; 375(6585):1133-1139. Edwards AM, Baric RS, Saphire EO, Ulmer JB. PMID: 35271333.
      View in: PubMed   Mentions:
    9. Pan-ebolavirus serology study of healthcare workers in the Mbandaka Health Region, Democratic Republic of the Congo. PLoS Negl Trop Dis. 2022 03; 16(3):e0010167. Shaffer KCL, Hui S, Bratcher A, King LB, Mutombe R, Kavira N, Kompany JP, Tambu M, Musene K, Mukadi P, Mbala P, Gadoth A, West BR, Ilunga BK, Kaba D, Muyembe-Tanfum JJ, Hoff NA, Rimoin AW, Saphire EO. PMID: 35255093; PMCID: PMC8929691.
      View in: PubMed   Mentions:
    10. CD164 is a host factor for lymphocytic choriomeningitis virus entry. Proc Natl Acad Sci U S A. 2022 03 08; 119(10):e2119676119. Bakkers MJG, Moon-Walker A, Herlo R, Brusic V, Stubbs SH, Hastie KM, Saphire EO, Kirchhausen TL, Whelan SPJ. PMID: 35235462; PMCID: PMC8915965.
      View in: PubMed   Mentions:
    11. A Manhattan Project against COVID. FASEB J. 2022 02; 36(2):e22117. Scolnick EM, Saphire EO. PMID: 35060642.
      View in: PubMed   Mentions:
    12. mRNA-1273 vaccine-induced antibodies maintain Fc effector functions across SARS-CoV-2 variants of concern. Immunity. 2022 02 08; 55(2):355-365.e4. Kaplonek P, Fischinger S, Cizmeci D, Bartsch YC, Kang J, Burke JS, Shin SA, Dayal D, Martin P, Mann C, Amanat F, Julg B, Nilles EJ, Musk ER, Menon AS, Krammer F, Saphire EO, Alter G. PMID: 35090580; PMCID: PMC8733218.
      View in: PubMed   Mentions:
    13. Rapid discovery of diverse neutralizing SARS-CoV-2 antibodies from large-scale synthetic phage libraries. MAbs. 2022 Jan-Dec; 14(1):2002236. Yuan TZ, Garg P, Wang L, Willis JR, Kwan E, Hernandez AGL, Tuscano E, Sever EN, Keane E, Soto C, Mucker EM, Fouch ME, Davidson E, Doranz BJ, Kailasan S, Aman MJ, Li H, Hooper JW, Saphire EO, Crowe JE, Liu Q, Axelrod F, Sato AK. PMID: 34967699; PMCID: PMC8726723.
      View in: PubMed   Mentions:
    14. Novel attempts launched toward universal Sarbecovirus vaccine. Cell Res. 2021 12; 31(12):1226-1227. Li H, Saphire EO. PMID: 34433899; PMCID: PMC8385477.
      View in: PubMed   Mentions:    Fields:    
    15. SARS-CoV-2 infection generates tissue-localized immunological memory in humans. Sci Immunol. 2021 Nov 19; 6(65):eabl9105. Poon MML, Rybkina K, Kato Y, Kubota M, Matsumoto R, Bloom NI, Zhang Z, Hastie KM, Grifoni A, Weiskopf D, Wells SB, Ural BB, Lam N, Szabo PA, Dogra P, Lee YS, Gray JI, Bradley MC, Brusko MA, Brusko TM, Saphire EO, Connors TJ, Sette A, Crotty S, Farber DL. PMID: 34618554; PMCID: PMC8626868.
      View in: PubMed   Mentions:    Fields:    
    16. Defining variant-resistant epitopes targeted by SARS-CoV-2 antibodies: A global consortium study. Science. 2021 Oct 22; 374(6566):472-478. Hastie KM, Li H, Bedinger D, Schendel SL, Dennison SM, Li K, Rayaprolu V, Yu X, Mann C, Zandonatti M, Diaz Avalos R, Zyla D, Buck T, Hui S, Shaffer K, Hariharan C, Yin J, Olmedillas E, Enriquez A, Parekh D, Abraha M, Feeney E, Horn GQ, CoVIC-DB team1, Aldon Y, Ali H, Aracic S, Cobb RR, Federman RS, Fernandez JM, Glanville J, Green R, Grigoryan G, Lujan Hernandez AG, Ho DD, Huang KA, Ingraham J, Jiang W, Kellam P, Kim C, Kim M, Kim HM, Kong C, Krebs SJ, Lan F, Lang G, Lee S, Leung CL, Liu J, Lu Y, MacCamy A, McGuire AT, Palser AL, Rabbitts TH, Rikhtegaran Tehrani Z, Sajadi MM, Sanders RW, Sato AK, Schweizer L, Seo J, Shen B, Snitselaar JL, Stamatatos L, Tan Y, Tomic MT, van Gils MJ, Youssef S, Yu J, Yuan TZ, Zhang Q, Peters B, Tomaras GD, Germann T, Saphire EO. PMID: 34554826.
      View in: PubMed   Mentions: 1     Fields:    
    17. Fab and Fc contribute to maximal protection against SARS-CoV-2 following NVX-CoV2373 subunit vaccine with Matrix-M vaccination. Cell Rep Med. 2021 09 21; 2(9):100405. Gorman MJ, Patel N, Guebre-Xabier M, Zhu AL, Atyeo C, Pullen KM, Loos C, Goez-Gazi Y, Carrion R, Tian JH, Yuan D, Bowman KA, Zhou B, Maciejewski S, McGrath ME, Logue J, Frieman MB, Montefiori D, Mann C, Schendel S, Amanat F, Krammer F, Saphire EO, Lauffenburger DA, Greene AM, Portnoff AD, Massare MJ, Ellingsworth L, Glenn G, Smith G, Alter G. PMID: 34485950; PMCID: PMC8405506.
      View in: PubMed   Mentions: 3  
    18. Subtle immunological differences in mRNA-1273 and BNT162b2 COVID-19 vaccine induced Fc-functional profiles. bioRxiv. 2021 Aug 31. Kaplonek P, Cizmeci D, Fischinger S, Collier AR, Suscovich T, Linde C, Broge T, Mann C, Amanat F, Dayal D, Rhee J, de St Aubin M, Nilles EJ, Musk ER, Menon AS, Saphire EO, Krammer F, Lauffenburger DA, Barouch DH, Alter G. PMID: 34494026; PMCID: PMC8423223.
      View in: PubMed   Mentions:
    19. Proteo-Genomic Analysis Identifies Two Major Sites of Vulnerability on Ebolavirus Glycoprotein for Neutralizing Antibodies in Convalescent Human Plasma. Front Immunol. 2021; 12:706757. Gilchuk P, Guthals A, Bonissone SR, Shaw JB, Ilinykh PA, Huang K, Bombardi RG, Liang J, Grinyo A, Davidson E, Chen EC, Gunn BM, Alter G, Saphire EO, Doranz BJ, Bukreyev A, Zeitlin L, Castellana N, Crowe JE. PMID: 34335620; PMCID: PMC8322977.
      View in: PubMed   Mentions:    Fields:    
    20. Ebola vaccine-induced protection in nonhuman primates correlates with antibody specificity and Fc-mediated effects. Sci Transl Med. 2021 07 14; 13(602). Meyer M, Gunn BM, Malherbe DC, Gangavarapu K, Yoshida A, Pietzsch C, Kuzmina NA, Saphire EO, Collins PL, Crowe JE, Zhu JJ, Suchard MA, Brining DL, Mire CE, Cross RW, Geisbert JB, Samal SK, Andersen KG, Alter G, Geisbert TW, Bukreyev A. PMID: 34261800; PMCID: PMC8675601.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    21. An intranasal vaccine durably protects against SARS-CoV-2 variants in mice. Cell Rep. 2021 07 27; 36(4):109452. Hassan AO, Shrihari S, Gorman MJ, Ying B, Yaun D, Raju S, Chen RE, Dmitriev IP, Kashentseva E, Adams LJ, Mann C, Davis-Gardner ME, Suthar MS, Shi PY, Saphire EO, Fremont DH, Curiel DT, Alter G, Diamond MS. PMID: 34289385; PMCID: PMC8270739.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsPHPublic Health
    22. Cellular mRNA triggers structural transformation of Ebola virus matrix protein VP40 to its essential regulatory form. Cell Rep. 2021 04 13; 35(2):108986. Landeras-Bueno S, Wasserman H, Oliveira G, VanAernum ZL, Busch F, Salie ZL, Wysocki VH, Andersen K, Saphire EO. PMID: 33852858; PMCID: PMC8568338.
      View in: PubMed   Mentions: 2     Fields:    
    23. A Fc engineering approach to define functional humoral correlates of immunity against Ebola virus. Immunity. 2021 04 13; 54(4):815-828.e5. Gunn BM, Lu R, Slein MD, Ilinykh PA, Huang K, Atyeo C, Schendel SL, Kim J, Cain C, Roy V, Suscovich TJ, Takada A, Halfmann PJ, Kawaoka Y, Pauthner MG, Momoh M, Goba A, Kanneh L, Andersen KG, Schieffelin JS, Grant D, Garry RF, Saphire EO, Bukreyev A, Alter G. PMID: 33852832; PMCID: PMC8111768.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    24. Collaboration between the Fab and Fc contribute to maximal protection against SARS-CoV-2 following NVX-CoV2373 subunit vaccine with Matrix-M™ vaccination. Res Sq. 2021 Feb 15. Alter G, Gorman M, Patel N, Guebre-Xabier M, Zhu A, Atyeo C, Pullen K, Loos C, Goez-Gazi Y, Carrion R, Tian JH, Yuan D, Bowman K, Zhou B, Maciejewski S, McGrath M, Logue J, Frieman M, Montefiori D, Schendel S, Saphire EO, Lauffenburger D, Greene A, Portnoff A, Massare M, Ellingsworth L, Glenn G, Smith G, Mann C, Amanat F, Krammer F. PMID: 33619473; PMCID: PMC7899467.
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    25. Collaboration between the Fab and Fc contribute to maximal protection against SARS-CoV-2 in nonhuman primates following NVX-CoV2373 subunit vaccine with Matrix-M™ vaccination. bioRxiv. 2021 Feb 05. Gorman MJ, Patel N, Guebre-Xabier M, Zhu A, Atyeo C, Pullen KM, Loos C, Goez-Gazi Y, Carrion R, Tian JH, Yaun D, Bowman K, Zhou B, Maciejewski S, McGrath ME, Logue J, Frieman MB, Montefiori D, Mann C, Schendel S, Amanat F, Krammer F, Saphire EO, Lauffenburger D, Greene AM, Portnoff AD, Massare MJ, Ellingsworth L, Glenn G, Smith G, Alter G. PMID: 33564763; PMCID: PMC7872351.
      View in: PubMed   Mentions:
    26. Evidence for distinct mechanisms of small molecule inhibitors of filovirus entry. PLoS Pathog. 2021 02; 17(2):e1009312. Schafer A, Xiong R, Cooper L, Nowar R, Lee H, Li Y, Ramirez BE, Peet NP, Caffrey M, Thatcher GRJ, Saphire EO, Cheng H, Rong L. PMID: 33539432; PMCID: PMC7888603.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    27. Prominent Neutralizing Antibody Response Targeting the Ebolavirus Glycoprotein Subunit Interface Elicited by Immunization. J Virol. 2021 Feb 03. Wang Y, Howell KA, Brannan J, Agans KN, Turner HL, Wirchnianski AS, Kailasan S, Fusco M, Galkin A, Chiang CI, Zhao X, Saphire EO, Chandran K, Ward AB, Dye JM, Aman MJ, Geisbert TW, Li Y. PMID: 33536172; PMCID: PMC8103683.
      View in: PubMed   Mentions: 1     Fields:    
    28. Immunological memory to SARS-CoV-2 assessed for up to 8 months after infection. Science. 2021 02 05; 371(6529). Dan JM, Mateus J, Kato Y, Hastie KM, Yu ED, Faliti CE, Grifoni A, Ramirez SI, Haupt S, Frazier A, Nakao C, Rayaprolu V, Rawlings SA, Peters B, Krammer F, Simon V, Saphire EO, Smith DM, Weiskopf D, Sette A, Crotty S. PMID: 33408181; PMCID: PMC7919858.
      View in: PubMed   Mentions: 364     Fields:    Translation:HumansCells
    29. Structural biology in the fight against COVID-19. Nat Struct Mol Biol. 2021 01; 28(1):2-7. Bárcena M, Barnes CO, Beck M, Bjorkman PJ, Canard B, Gao GF, Gao Y, Hilgenfeld R, Hummer G, Patwardhan A, Santoni G, Saphire EO, Schaffitzel C, Schendel SL, Smith JL, Thorn A, Veesler D, Zhang P, Zhou Q. PMID: 33437043.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    30. Analysis of Oligomeric and Glycosylated Proteins by Size-Exclusion Chromatography Coupled with Multiangle Light Scattering. Methods Mol Biol. 2021; 2271:343-359. Hastie K, Rayaprolu V, Saphire EO. PMID: 33908019.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    31. Immunological memory to SARS-CoV-2 assessed for up to eight months after infection. bioRxiv. 2020 Dec 18. Dan JM, Mateus J, Kato Y, Hastie KM, Yu ED, Faliti CE, Grifoni A, Ramirez SI, Haupt S, Frazier A, Nakao C, Rayaprolu V, Rawlings SA, Peters B, Krammer F, Simon V, Saphire EO, Smith DM, Weiskopf D, Sette A, Crotty S. PMID: 33442687; PMCID: PMC7805444.
      View in: PubMed   Mentions:
    32. Ebola and Marburg virus matrix layers are locally ordered assemblies of VP40 dimers. Elife. 2020 10 05; 9. Wan W, Clarke M, Norris MJ, Kolesnikova L, Koehler A, Bornholdt ZA, Becker S, Saphire EO, Briggs JA. PMID: 33016878; PMCID: PMC7588233.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    33. Lifted Up from Lockdown. Cell. 2020 10 01; 183(1):1-3. Arturo EC, Saphire EO. PMID: 33007260; PMCID: PMC7528821.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansPHPublic Health
    34. Antibodies from Sierra Leonean and Nigerian Lassa fever survivors cross-react with recombinant proteins representing Lassa viruses of divergent lineages. Sci Rep. 2020 09 29; 10(1):16030. Heinrich ML, Boisen ML, Nelson DKS, Bush DJ, Cross RW, Koval AP, Hoffmann AR, Beddingfield BJ, Hastie KM, Rowland MM, Aimukanova I, Koval S, Lathigra R, Borisevich V, Momoh M, Sandi JD, Goba A, Odia L, Baimba F, Aiyepada JO, Ebo B, Eromon P, Ugwu C, Folarin O, Olumade T, Onyechi MN, Etafo J, Adeyemi R, Ella EE, Aminu M, Gomerep SS, Eke MA, Ogunsanya O, Akpede GO, Asogun DO, Okogbenin SA, Okokhere PO, Holst J, Shaffer JG, Schieffelin JS, Geisbert TW, Saphire EO, Happi CT, Grant DS, Garry RF, Branco LM. PMID: 32994446; PMCID: PMC7525497.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCellsPHPublic Health
    35. SnapShot: Enveloped Virus Entry. Cell. 2020 08 06; 182(3):786-786.e1. Mercer J, Lee JE, Saphire EO, Freeman SA. PMID: 32763187; PMCID: PMC7409976.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    36. Tracking Changes in SARS-CoV-2 Spike: Evidence that D614G Increases Infectivity of the COVID-19 Virus. Cell. 2020 08 20; 182(4):812-827.e19. Korber B, Fischer WM, Gnanakaran S, Yoon H, Theiler J, Abfalterer W, Hengartner N, Giorgi EE, Bhattacharya T, Foley B, Hastie KM, Parker MD, Partridge DG, Evans CM, Freeman TM, de Silva TI, Sheffield COVID-19 Genomics Group, McDanal C, Perez LG, Tang H, Moon-Walker A, Whelan SP, LaBranche CC, Saphire EO, Montefiori DC. PMID: 32697968; PMCID: PMC7332439.
      View in: PubMed   Mentions: 966     Fields:    Translation:HumansCellsPHPublic Health
    37. Spiking Pandemic Potential: Structural and Immunological Aspects of SARS-CoV-2. Trends Microbiol. 2020 08; 28(8):605-618. Wang YT, Landeras-Bueno S, Hsieh LE, Terada Y, Kim K, Ley K, Shresta S, Saphire EO, Regla-Nava JA. PMID: 32507543; PMCID: PMC7237910.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    38. Non-neutralizing Antibodies from a Marburg Infection Survivor Mediate Protection by Fc-Effector Functions and by Enhancing Efficacy of Other Antibodies. Cell Host Microbe. 2020 06 10; 27(6):976-991.e11. Ilinykh PA, Huang K, Santos RI, Gilchuk P, Gunn BM, Karim MM, Liang J, Fouch ME, Davidson E, Parekh DV, Kimble JB, Pietzsch CA, Meyer M, Kuzmina NA, Zeitlin L, Saphire EO, Alter G, Crowe JE, Bukreyev A. PMID: 32320678; PMCID: PMC7292764.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    39. Analysis of a Therapeutic Antibody Cocktail Reveals Determinants for Cooperative and Broad Ebolavirus Neutralization. Immunity. 2020 02 18; 52(2):388-403.e12. Gilchuk P, Murin CD, Milligan JC, Cross RW, Mire CE, Ilinykh PA, Huang K, Kuzmina N, Altman PX, Hui S, Gunn BM, Bryan AL, Davidson E, Doranz BJ, Turner HL, Alkutkar T, Flinko R, Orlandi C, Carnahan R, Nargi R, Bombardi RG, Vodzak ME, Li S, Okoli A, Ibeawuchi M, Ohiaeri B, Lewis GK, Alter G, Bukreyev A, Saphire EO, Geisbert TW, Ward AB, Crowe JE. PMID: 32023489; PMCID: PMC7111202.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    40. Reporter Assays for Ebola Virus Nucleoprotein Oligomerization, Virion-Like Particle Budding, and Minigenome Activity Reveal the Importance of Nucleoprotein Amino Acid Position 111. Viruses. 2020 01 15; 12(1). Lin AE, Diehl WE, Cai Y, Finch CL, Akusobi C, Kirchdoerfer RN, Bollinger L, Schaffner SF, Brown EA, Saphire EO, Andersen KG, Kuhn JH, Luban J, Sabeti PC. PMID: 31952352; PMCID: PMC7019320.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    41. A glimpse into immune responses evolving against Ebola virus. Nat Med. 2019 10; 25(10):1470-1471. Saphire EO. PMID: 31591604.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    42. Diverse Morphology and Structural Features of Old and New World Hantaviruses. Viruses. 2019 09 16; 11(9). Parvate A, Williams EP, Taylor MK, Chu YK, Lanman J, Saphire EO, Jonsson CB. PMID: 31527500; PMCID: PMC6783877.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    43. Convergent Structures Illuminate Features for Germline Antibody Binding and Pan-Lassa Virus Neutralization. Cell. 2019 08 08; 178(4):1004-1015.e14. Hastie KM, Cross RW, Harkins SS, Zandonatti MA, Koval AP, Heinrich ML, Rowland MM, Robinson JE, Geisbert TW, Garry RF, Branco LM, Saphire EO. PMID: 31398326; PMCID: PMC6814208.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    44. Sudan Ebolavirus VP35-NP Crystal Structure Reveals a Potential Target for Pan-Filovirus Treatment. mBio. 2019 07 23; 10(4). Landeras-Bueno S, Oda SI, Norris MJ, Li Salie Z, Guenaga J, Wyatt RT, Saphire EO. PMID: 31337716; PMCID: PMC6650547.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    45. Longitudinal Analysis of the Human B Cell Response to Ebola Virus Infection. Cell. 2019 05 30; 177(6):1566-1582.e17. Davis CW, Jackson KJL, McElroy AK, Halfmann P, Huang J, Chennareddy C, Piper AE, Leung Y, Albariño CG, Crozier I, Ellebedy AH, Sidney J, Sette A, Yu T, Nielsen SCA, Goff AJ, Spiropoulou CF, Saphire EO, Cavet G, Kawaoka Y, Mehta AK, Glass PJ, Boyd SD, Ahmed R. PMID: 31104840; PMCID: PMC6908968.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansAnimalsCells
    46. Cryo-EM structure of the Ebola virus nucleoprotein-RNA complex. Acta Crystallogr F Struct Biol Commun. 2019 May 01; 75(Pt 5):340-347. Kirchdoerfer RN, Saphire EO, Ward AB. PMID: 31045563; PMCID: PMC6497097.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    47. Cross-reactive neutralizing human survivor monoclonal antibody BDBV223 targets the ebolavirus stalk. Nat Commun. 2019 04 17; 10(1):1788. King LB, West BR, Moyer CL, Gilchuk P, Flyak A, Ilinykh PA, Bombardi R, Hui S, Huang K, Bukreyev A, Crowe JE, Saphire EO. PMID: 30996276; PMCID: PMC6470140.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    48. Early Human B Cell Response to Ebola Virus in Four U.S. Survivors of Infection. J Virol. 2019 04 15; 93(8). Williamson LE, Flyak AI, Kose N, Bombardi R, Branchizio A, Reddy S, Davidson E, Doranz BJ, Fusco ML, Saphire EO, Halfmann PJ, Kawaoka Y, Piper AE, Glass PJ, Crowe JE. PMID: 30728263; PMCID: PMC6450119.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    49. Structural basis of broad ebolavirus neutralization by a human survivor antibody. Nat Struct Mol Biol. 2019 03; 26(3):204-212. West BR, Wec AZ, Moyer CL, Fusco ML, Ilinykh PA, Huang K, Wirchnianski AS, James RM, Herbert AS, Hui S, Goodwin E, Howell KA, Kailasan S, Aman MJ, Walker LM, Dye JM, Bukreyev A, Chandran K, Saphire EO. PMID: 30833785; PMCID: PMC6402988.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    50. A Conserved Basic Patch and Central Kink in the Nipah Virus Phosphoprotein Multimerization Domain Are Essential for Polymerase Function. Structure. 2019 04 02; 27(4):660-668.e4. Bruhn JF, Hotard AL, Spiropoulou CF, Lo MK, Saphire EO. PMID: 30799076; PMCID: PMC6690496.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    51. Structural Characterization of Pan-Ebolavirus Antibody 6D6 Targeting the Fusion Peptide of the Surface Glycoprotein. J Infect Dis. 2019 01 09; 219(3):415-419. Milligan JC, Parekh DV, Fuller KM, Igarashi M, Takada A, Saphire EO. PMID: 30203042; PMCID: PMC6325343.
      View in: PubMed   Mentions: 7     Fields:    Translation:Cells
    52. In Vivo Delivery of Synthetic Human DNA-Encoded Monoclonal Antibodies Protect against Ebolavirus Infection in a Mouse Model. Cell Rep. 2018 11 13; 25(7):1982-1993.e4. Patel A, Park DH, Davis CW, Smith TRF, Leung A, Tierney K, Bryan A, Davidson E, Yu X, Racine T, Reed C, Gorman ME, Wise MC, Elliott STC, Esquivel R, Yan J, Chen J, Muthumani K, Doranz BJ, Saphire EO, Crowe JE, Broderick KE, Kobinger GP, He S, Qiu X, Kobasa D, Humeau L, Sardesai NY, Ahmed R, Weiner DB. PMID: 30428362; PMCID: PMC6319964.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    53. Antibody-mediated protection against Ebola virus. Nat Immunol. 2018 11; 19(11):1169-1178. Saphire EO, Schendel SL, Gunn BM, Milligan JC, Alter G. PMID: 30333617; PMCID: PMC6814399.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansAnimalsCells
    54. Structural Basis of Pan-Ebolavirus Neutralization by a Human Antibody against a Conserved, yet Cryptic Epitope. mBio. 2018 09 11; 9(5). West BR, Moyer CL, King LB, Fusco ML, Milligan JC, Hui S, Saphire EO. PMID: 30206174; PMCID: PMC6134094.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    55. Antibody Repertoires to the Same Ebola Vaccine Antigen Are Differentially Affected by Vaccine Vectors. Cell Rep. 2018 08 14; 24(7):1816-1829. Meyer M, Yoshida A, Ramanathan P, Saphire EO, Collins PL, Crowe JE, Samal S, Bukreyev A. PMID: 30110638; PMCID: PMC6145141.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    56. Systematic Analysis of Monoclonal Antibodies against Ebola Virus GP Defines Features that Contribute to Protection. Cell. 2018 08 09; 174(4):938-952.e13. Saphire EO, Schendel SL, Fusco ML, Gangavarapu K, Gunn BM, Wec AZ, Halfmann PJ, Brannan JM, Herbert AS, Qiu X, Wagh K, He S, Giorgi EE, Theiler J, Pommert KBJ, Krause TB, Turner HL, Murin CD, Pallesen J, Davidson E, Ahmed R, Aman MJ, Bukreyev A, Burton DR, Crowe JE, Davis CW, Georgiou G, Krammer F, Kyratsous CA, Lai JR, Nykiforuk C, Pauly MH, Rijal P, Takada A, Townsend AR, Volchkov V, Walker LM, Wang CI, Zeitlin L, Doranz BJ, Ward AB, Korber B, Kobinger GP, Andersen KG, Kawaoka Y, Alter G, Chandran K, Dye JM, Viral Hemorrhagic Fever Immunotherapeutic Consortium. PMID: 30096313; PMCID: PMC6102396.
      View in: PubMed   Mentions: 71     Fields:    Translation:AnimalsCellsPHPublic Health
    57. A Role for Fc Function in Therapeutic Monoclonal Antibody-Mediated Protection against Ebola Virus. Cell Host Microbe. 2018 08 08; 24(2):221-233.e5. Gunn BM, Yu WH, Karim MM, Brannan JM, Herbert AS, Wec AZ, Halfmann PJ, Fusco ML, Schendel SL, Gangavarapu K, Krause T, Qiu X, He S, Das J, Suscovich TJ, Lai J, Chandran K, Zeitlin L, Crowe JE, Lauffenburger D, Kawaoka Y, Kobinger GP, Andersen KG, Dye JM, Saphire EO, Alter G. PMID: 30092199; PMCID: PMC6298217.
      View in: PubMed   Mentions: 69  Translation:HumansAnimalsCells
    58. Multifunctional Pan-ebolavirus Antibody Recognizes a Site of Broad Vulnerability on the Ebolavirus Glycoprotein. Immunity. 2018 08 21; 49(2):363-374.e10. Gilchuk P, Kuzmina N, Ilinykh PA, Huang K, Gunn BM, Bryan A, Davidson E, Doranz BJ, Turner HL, Fusco ML, Bramble MS, Hoff NA, Binshtein E, Kose N, Flyak AI, Flinko R, Orlandi C, Carnahan R, Parrish EH, Sevy AM, Bombardi RG, Singh PK, Mukadi P, Muyembe-Tamfum JJ, Ohi MD, Saphire EO, Lewis GK, Alter G, Ward AB, Rimoin AW, Bukreyev A, Crowe JE. PMID: 30029854; PMCID: PMC6104738.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    59. The structural basis for filovirus neutralization by monoclonal antibodies. Curr Opin Immunol. 2018 08; 53:196-202. King LB, West BR, Schendel SL, Saphire EO. PMID: 29940415; PMCID: PMC6141344.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    60. Lassa virus glycoprotein: stopping a moving target. Curr Opin Virol. 2018 08; 31:52-58. Hastie KM, Saphire EO. PMID: 29843991; PMCID: PMC6193841.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    61. Broadly neutralizing antibodies from human survivors target a conserved site in the Ebola virus glycoprotein HR2-MPER region. Nat Microbiol. 2018 06; 3(6):670-677. Flyak AI, Kuzmina N, Murin CD, Bryan C, Davidson E, Gilchuk P, Gulka CP, Ilinykh PA, Shen X, Huang K, Ramanathan P, Turner H, Fusco ML, Lampley R, Kose N, King H, Sapparapu G, Doranz BJ, Ksiazek TG, Wright DW, Saphire EO, Ward AB, Bukreyev A, Crowe JE. PMID: 29736037; PMCID: PMC6030461.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    62. Field validation of recombinant antigen immunoassays for diagnosis of Lassa fever. Sci Rep. 2018 04 12; 8(1):5939. Boisen ML, Hartnett JN, Shaffer JG, Goba A, Momoh M, Sandi JD, Fullah M, Nelson DKS, Bush DJ, Rowland MM, Heinrich ML, Koval AP, Cross RW, Barnes KG, Lachenauer AE, Lin AE, Nekoui M, Kotliar D, Winnicki SM, Siddle KJ, Gbakie M, Fonnie M, Koroma VJ, Kanneh L, Kulakosky PC, Hastie KM, Wilson RB, Andersen KG, Folarin OO, Happi CT, Sabeti PC, Geisbert TW, Saphire EO, Khan SH, Grant DS, Schieffelin JS, Branco LM, Garry RF. PMID: 29651117; PMCID: PMC5897328.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    63. A cationic, C-terminal patch and structural rearrangements in Ebola virus matrix VP40 protein control its interactions with phosphatidylserine. J Biol Chem. 2018 03 02; 293(9):3335-3349. Del Vecchio K, Frick CT, Gc JB, Oda SI, Gerstman BS, Saphire EO, Chapagain PP, Stahelin RV. PMID: 29348171; PMCID: PMC5836117.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    64. The Marburgvirus-Neutralizing Human Monoclonal Antibody MR191 Targets a Conserved Site to Block Virus Receptor Binding. Cell Host Microbe. 2018 Jan 10; 23(1):101-109.e4. King LB, Fusco ML, Flyak AI, Ilinykh PA, Huang K, Gunn B, Kirchdoerfer RN, Hastie KM, Sangha AK, Meiler J, Alter G, Bukreyev A, Crowe JE, Saphire EO. PMID: 29324225; PMCID: PMC5772738.
      View in: PubMed   Mentions: 15  Translation:HumansAnimalsCells
    65. Role of Non-local Interactions between CDR Loops in Binding Affinity of MR78 Antibody to Marburg Virus Glycoprotein. Structure. 2017 12 05; 25(12):1820-1828.e2. Sangha AK, Dong J, Williamson L, Hashiguchi T, Saphire EO, Crowe JE, Meiler J. PMID: 29153506; PMCID: PMC5718948.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    66. Structural basis for antibody-mediated neutralization of Lassa virus. Science. 2017 06 02; 356(6341):923-928. Hastie KM, Zandonatti MA, Kleinfelter LM, Heinrich ML, Rowland MM, Chandran K, Branco LM, Robinson JE, Garry RF, Saphire EO. PMID: 28572385; PMCID: PMC6007842.
      View in: PubMed   Mentions: 67     Fields:    Translation:HumansCells
    67. How to turn competitors into collaborators. Nature. 2017 01 18; 541(7637):283-285. Saphire EO, Dye JM, Kobinger GP, Zeitlin L, Chandran K, Garry RF. PMID: 28102273.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    68. Crystal Structure of the Marburg Virus VP35 Oligomerization Domain. J Virol. 2017 Jan 15; 91(2). Bruhn JF, Kirchdoerfer RN, Urata SM, Li S, Tickle IJ, Bricogne G, Saphire EO. PMID: 27847355; PMCID: PMC5215338.
      View in: PubMed   Mentions: 19     Fields:    Translation:Cells
    69. Filovirus Structural Biology: The Molecules in the Machine. Curr Top Microbiol Immunol. 2017; 411:381-417. Kirchdoerfer RN, Wasserman H, Amarasinghe GK, Saphire EO. PMID: 28795188.
      View in: PubMed   Mentions: 9     Fields:    Translation:Cells
    70. The Ebola Virus VP30-NP Interaction Is a Regulator of Viral RNA Synthesis. PLoS Pathog. 2016 Oct; 12(10):e1005937. Kirchdoerfer RN, Moyer CL, Abelson DM, Saphire EO. PMID: 27755595; PMCID: PMC5068707.
      View in: PubMed   Mentions: 24     Fields:    Translation:Cells
    71. A "Trojan horse" bispecific-antibody strategy for broad protection against ebolaviruses. Science. 2016 10 21; 354(6310):350-354. Wec AZ, Nyakatura EK, Herbert AS, Howell KA, Holtsberg FW, Bakken RR, Mittler E, Christin JR, Shulenin S, Jangra RK, Bharrhan S, Kuehne AI, Bornholdt ZA, Flyak AI, Saphire EO, Crowe JE, Aman MJ, Dye JM, Lai JR, Chandran K. PMID: 27608667; PMCID: PMC5647781.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansAnimalsCells
    72. Analytical Validation of the ReEBOV Antigen Rapid Test for Point-of-Care Diagnosis of Ebola Virus Infection. J Infect Dis. 2016 10 15; 214(suppl 3):S210-S217. Cross RW, Boisen ML, Millett MM, Nelson DS, Oottamasathien D, Hartnett JN, Jones AB, Goba A, Momoh M, Fullah M, Bornholdt ZA, Fusco ML, Abelson DM, Oda S, Brown BL, Pham H, Rowland MM, Agans KN, Geisbert JB, Heinrich ML, Kulakosky PC, Shaffer JG, Schieffelin JS, Kargbo B, Gbetuwa M, Gevao SM, Wilson RB, Saphire EO, Pitts KR, Khan SH, Grant DS, Geisbert TW, Branco LM, Garry RF. PMID: 27587634; PMCID: PMC5050482.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    73. Structures of Ebola virus GP and sGP in complex with therapeutic antibodies. Nat Microbiol. 2016 Aug 08; 1(9):16128. Pallesen J, Murin CD, de Val N, Cottrell CA, Hastie KM, Turner HL, Fusco ML, Flyak AI, Zeitlin L, Crowe JE, Andersen KG, Saphire EO, Ward AB. PMID: 27562261; PMCID: PMC5003320.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansCells
    74. More than Meets the Eye: Hidden Structures in the Proteome. Annu Rev Virol. 2016 09 29; 3(1):373-386. Wasserman H, Saphire EO. PMID: 27482901.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    75. An Outbreak of Ebola Virus Disease in the Lassa Fever Zone. J Infect Dis. 2016 10 15; 214(suppl 3):S110-S121. Goba A, Khan SH, Fonnie M, Fullah M, Moigboi A, Kovoma A, Sinnah V, Yoko N, Rogers H, Safai S, Momoh M, Koroma V, Kamara FK, Konowu E, Yillah M, French I, Mustapha I, Kanneh F, Foday M, McCarthy H, Kallon T, Kallon M, Naiebu J, Sellu J, Jalloh AA, Gbakie M, Kanneh L, Massaly JL, Kargbo D, Kargbo B, Vandi M, Gbetuwa M, Gevao SM, Sandi JD, Jalloh SC, Grant DS, Blyden SO, Crozier I, Schieffelin JS, McLellan SL, Jacob ST, Boisen ML, Hartnett JN, Cross RW, Branco LM, Andersen KG, Yozwiak NL, Gire SK, Tariyal R, Park DJ, Haislip AM, Bishop CM, Melnik LI, Gallaher WR, Wimley WC, He J, Shaffer JG, Sullivan BM, Grillo S, Oman S, Garry CE, Edwards DR, McCormick SJ, Elliott DH, Rouelle JA, Kannadka CB, Reyna AA, Bradley BT, Yu H, Yenni RE, Hastie KM, Geisbert JB, Kulakosky PC, Wilson RB, Oldstone MB, Pitts KR, Henderson LA, Robinson JE, Geisbert TW, Saphire EO, Happi CT, Asogun DA, Sabeti PC, Garry RF, Viral Hemorrhagic Fever Consortium. PMID: 27402779; PMCID: PMC5050470.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCellsPHPublic Health
    76. Feverish Quest for Ebola Immunotherapy: Straight or Cocktail? Trends Microbiol. 2016 09; 24(9):684-686. Saphire EO, Aman MJ. PMID: 27338027.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    77. Most neutralizing human monoclonal antibodies target novel epitopes requiring both Lassa virus glycoprotein subunits. Nat Commun. 2016 05 10; 7:11544. Robinson JE, Hastie KM, Cross RW, Yenni RE, Elliott DH, Rouelle JA, Kannadka CB, Smira AA, Garry CE, Bradley BT, Yu H, Shaffer JG, Boisen ML, Hartnett JN, Zandonatti MA, Rowland MM, Heinrich ML, Martínez-Sobrido L, Cheng B, de la Torre JC, Andersen KG, Goba A, Momoh M, Fullah M, Gbakie M, Kanneh L, Koroma VJ, Fonnie R, Jalloh SC, Kargbo B, Vandi MA, Gbetuwa M, Ikponmwosa O, Asogun DA, Okokhere PO, Follarin OA, Schieffelin JS, Pitts KR, Geisbert JB, Kulakoski PC, Wilson RB, Happi CT, Sabeti PC, Gevao SM, Khan SH, Grant DS, Geisbert TW, Saphire EO, Branco LM, Garry RF. PMID: 27161536; PMCID: PMC4866400.
      View in: PubMed   Mentions: 60     Fields:    Translation:HumansCells
    78. Antibody Treatment of Ebola and Sudan Virus Infection via a Uniquely Exposed Epitope within the Glycoprotein Receptor-Binding Site. Cell Rep. 2016 05 17; 15(7):1514-1526. Howell KA, Qiu X, Brannan JM, Bryan C, Davidson E, Holtsberg FW, Wec AZ, Shulenin S, Biggins JE, Douglas R, Enterlein SG, Turner HL, Pallesen J, Murin CD, He S, Kroeker A, Vu H, Herbert AS, Fusco ML, Nyakatura EK, Lai JR, Keck ZY, Foung SKH, Saphire EO, Zeitlin L, Ward AB, Chandran K, Doranz BJ, Kobinger GP, Dye JM, Aman MJ. PMID: 27160900; PMCID: PMC4871745.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansAnimalsCells
    79. Crystal structure of the prefusion surface glycoprotein of the prototypic arenavirus LCMV. Nat Struct Mol Biol. 2016 06; 23(6):513-521. Hastie KM, Igonet S, Sullivan BM, Legrand P, Zandonatti MA, Robinson JE, Garry RF, Rey FA, Oldstone MB, Saphire EO. PMID: 27111888; PMCID: PMC4945123.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimalsCells
    80. Crystal Structure of the Oligomeric Form of Lassa Virus Matrix Protein Z. J Virol. 2016 May; 90(9):4556-62. Hastie KM, Zandonatti M, Liu T, Li S, Woods VL, Saphire EO. PMID: 26912609; PMCID: PMC4836352.
      View in: PubMed   Mentions: 13     Fields:    Translation:Cells
    81. Two-mAb cocktail protects macaques against the Makona variant of Ebola virus. Sci Transl Med. 2016 Mar 09; 8(329):329ra33. Qiu X, Audet J, Lv M, He S, Wong G, Wei H, Luo L, Fernando L, Kroeker A, Fausther Bovendo H, Bello A, Li F, Ye P, Jacobs M, Ippolito G, Saphire EO, Bi S, Shen B, Gao GF, Zeitlin L, Feng J, Zhang B, Kobinger GP. PMID: 26962157; PMCID: PMC5814125.
      View in: PubMed   Mentions: 35     Fields:    Translation:AnimalsCells
    82. Host-Primed Ebola Virus GP Exposes a Hydrophobic NPC1 Receptor-Binding Pocket, Revealing a Target for Broadly Neutralizing Antibodies. mBio. 2016 Feb 23; 7(1):e02154-15. Bornholdt ZA, Ndungo E, Fusco ML, Bale S, Flyak AI, Crowe JE, Chandran K, Saphire EO. PMID: 26908579; PMCID: PMC4791852.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansCells
    83. Isolation of potent neutralizing antibodies from a survivor of the 2014 Ebola virus outbreak. Science. 2016 Mar 04; 351(6277):1078-83. Bornholdt ZA, Turner HL, Murin CD, Li W, Sok D, Souders CA, Piper AE, Goff A, Shamblin JD, Wollen SE, Sprague TR, Fusco ML, Pommert KB, Cavacini LA, Smith HL, Klempner M, Reimann KA, Krauland E, Gerngross TU, Wittrup KD, Saphire EO, Burton DR, Glass PJ, Ward AB, Walker LM. PMID: 26912366; PMCID: PMC4900763.
      View in: PubMed   Mentions: 88     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    84. Cross-Reactive and Potent Neutralizing Antibody Responses in Human Survivors of Natural Ebolavirus Infection. Cell. 2016 Jan 28; 164(3):392-405. Flyak AI, Shen X, Murin CD, Turner HL, David JA, Fusco ML, Lampley R, Kose N, Ilinykh PA, Kuzmina N, Branchizio A, King H, Brown L, Bryan C, Davidson E, Doranz BJ, Slaughter JC, Sapparapu G, Klages C, Ksiazek TG, Saphire EO, Ward AB, Bukreyev A, Crowe JE. PMID: 26806128; PMCID: PMC4733404.
      View in: PubMed   Mentions: 76     Fields:    Translation:HumansAnimalsCells
    85. Crystal Structure of Marburg Virus VP40 Reveals a Broad, Basic Patch for Matrix Assembly and a Requirement of the N-Terminal Domain for Immunosuppression. J Virol. 2016 02 15; 90(4):1839-48. Oda S, Noda T, Wijesinghe KJ, Halfmann P, Bornholdt ZA, Abelson DM, Armbrust T, Stahelin RV, Kawaoka Y, Saphire EO. PMID: 26656687; PMCID: PMC4733994.
      View in: PubMed   Mentions: 16     Fields:    Translation:Cells
    86. Potent Antibody Protection against an Emerging Alphavirus Threat. Cell. 2015 Nov 19; 163(5):1053-1054. Kielian M, Saphire EO. PMID: 26590413.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    87. Pan-ebolavirus and Pan-filovirus Mouse Monoclonal Antibodies: Protection against Ebola and Sudan Viruses. J Virol. 2016 01 01; 90(1):266-78. Holtsberg FW, Shulenin S, Vu H, Howell KA, Patel SJ, Gunn B, Karim M, Lai JR, Frei JC, Nyakatura EK, Zeitlin L, Douglas R, Fusco ML, Froude JW, Saphire EO, Herbert AS, Wirchnianski AS, Lear-Rooney CM, Alter G, Dye JM, Glass PJ, Warfield KL, Aman MJ. PMID: 26468533; PMCID: PMC4702560.
      View in: PubMed   Mentions: 46     Fields:    Translation:AnimalsCells
    88. Correction: Protective mAbs and Cross-Reactive mAbs Raised by Immunization with Engineered Marburg Virus GPs. PLoS Pathog. 2015 Oct; 11(10):e1005212. Fusco ML, Hashiguchi T, Cassan R, Biggins JE, Murin CD, Warfield KL, Li S, Holtsberg FW, Shulenin S, Vu H, Olinger GG, Kim DH, Whaley KJ, Zeitlin L, Ward AB, Nykiforuk C, Aman MJ, Berry JD, Saphire EO. PMID: 26452225; PMCID: PMC4599913.
      View in: PubMed   Mentions: 1     Fields:    
    89. Swift antibodies to counter emerging viruses. Proc Natl Acad Sci U S A. 2015 Aug 18; 112(33):10082-3. Burton DR, Saphire EO. PMID: 26261336; PMCID: PMC4547222.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    90. Development of Prototype Filovirus Recombinant Antigen Immunoassays. J Infect Dis. 2015 Oct 01; 212 Suppl 2:S359-67. Boisen ML, Oottamasathien D, Jones AB, Millett MM, Nelson DS, Bornholdt ZA, Fusco ML, Abelson DM, Oda S, Hartnett JN, Rowland MM, Heinrich ML, Akdag M, Goba A, Momoh M, Fullah M, Baimba F, Gbakie M, Safa S, Fonnie R, Kanneh L, Cross RW, Geisbert JB, Geisbert TW, Kulakosky PC, Grant DS, Shaffer JG, Schieffelin JS, Wilson RB, Saphire EO, Branco LM, Garry RF, Khan SH, Pitts KR, Viral Hemorrhagic Fever Consortium. PMID: 26232440; PMCID: PMC4564556.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    91. Protective mAbs and Cross-Reactive mAbs Raised by Immunization with Engineered Marburg Virus GPs. PLoS Pathog. 2015 Jun; 11(6):e1005016. Fusco ML, Hashiguchi T, Cassan R, Biggins JE, Murin CD, Warfield KL, Li S, Holtsberg FW, Shulenin S, Vu H, Olinger GG, Kim DH, Whaley KJ, Zeitlin L, Ward AB, Nykiforuk C, Aman MJ, Berry JD, Berry J, Saphire EO. PMID: 26115029; PMCID: PMC4482612.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCellsPHPublic Health
    92. Assembly of the Ebola Virus Nucleoprotein from a Chaperoned VP35 Complex. Cell Rep. 2015 Jul 07; 12(1):140-149. Kirchdoerfer RN, Abelson DM, Li S, Wood MR, Saphire EO. PMID: 26119732; PMCID: PMC4500542.
      View in: PubMed   Mentions: 47     Fields:    Translation:Cells
    93. New Advances in the Effort against Ebola. Cell Host Microbe. 2015 May 13; 17(5):545-7. Saphire EO. PMID: 25974296.
      View in: PubMed   Mentions: 1  Translation:HumansAnimalsCells
    94. High-resolution Crystal Structure of Dimeric VP40 From Sudan ebolavirus. J Infect Dis. 2015 Oct 01; 212 Suppl 2:S167-71. Clifton MC, Bruhn JF, Atkins K, Webb TL, Baydo RO, Raymond A, Lorimer DD, Edwards TE, Myler PJ, Saphire EO. PMID: 25957961; PMCID: PMC4564533.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    95. Structural basis for Marburg virus neutralization by a cross-reactive human antibody. Cell. 2015 Feb 26; 160(5):904-912. Hashiguchi T, Fusco ML, Bornholdt ZA, Lee JE, Flyak AI, Matsuoka R, Kohda D, Yanagi Y, Hammel M, Crowe JE, Saphire EO. PMID: 25723165; PMCID: PMC4344967.
      View in: PubMed   Mentions: 58     Fields:    Translation:HumansAnimalsCells
    96. Mechanism of human antibody-mediated neutralization of Marburg virus. Cell. 2015 Feb 26; 160(5):893-903. Flyak AI, Ilinykh PA, Murin CD, Garron T, Shen X, Fusco ML, Hashiguchi T, Bornholdt ZA, Slaughter JC, Sapparapu G, Klages C, Ksiazek TG, Ward AB, Saphire EO, Bukreyev A, Crowe JE. PMID: 25723164; PMCID: PMC4344968.
      View in: PubMed   Mentions: 79     Fields:    Translation:HumansAnimalsCells
    97. Multiple circulating infections can mimic the early stages of viral hemorrhagic fevers and possible human exposure to filoviruses in Sierra Leone prior to the 2014 outbreak. Viral Immunol. 2015 Feb; 28(1):19-31. Boisen ML, Schieffelin JS, Goba A, Oottamasathien D, Jones AB, Shaffer JG, Hastie KM, Hartnett JN, Momoh M, Fullah M, Gabiki M, Safa S, Zandonatti M, Fusco M, Bornholdt Z, Abelson D, Gire SK, Andersen KG, Tariyal R, Stremlau M, Cross RW, Geisbert JB, Pitts KR, Geisbert TW, Kulakoski P, Wilson RB, Henderson L, Sabeti PC, Grant DS, Garry RF, Saphire EO, Branco LM, Khan SH, Viral Hemorrhagic Fever Consortium. PMID: 25531344; PMCID: PMC4287116.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansPHPublic Health
    98. Structures of protective antibodies reveal sites of vulnerability on Ebola virus. Proc Natl Acad Sci U S A. 2014 Dec 02; 111(48):17182-7. Murin CD, Fusco ML, Bornholdt ZA, Qiu X, Olinger GG, Zeitlin L, Kobinger GP, Ward AB, Saphire EO. PMID: 25404321; PMCID: PMC4260551.
      View in: PubMed   Mentions: 88     Fields:    Translation:AnimalsCells
    99. Filovirus RefSeq entries: evaluation and selection of filovirus type variants, type sequences, and names. Viruses. 2014 Sep 26; 6(9):3663-82. Kuhn JH, Andersen KG, Bào Y, Bavari S, Becker S, Bennett RS, Bergman NH, Blinkova O, Bradfute S, Brister JR, Bukreyev A, Chandran K, Chepurnov AA, Davey RA, Dietzgen RG, Doggett NA, Dolnik O, Dye JM, Enterlein S, Fenimore PW, Formenty P, Freiberg AN, Garry RF, Garza NL, Gire SK, Gonzalez JP, Griffiths A, Happi CT, Hensley LE, Herbert AS, Hevey MC, Hoenen T, Honko AN, Ignatyev GM, Jahrling PB, Johnson JC, Johnson KM, Kindrachuk J, Klenk HD, Kobinger G, Kochel TJ, Lackemeyer MG, Lackner DF, Leroy EM, Lever MS, Mühlberger E, Netesov SV, Olinger GG, Omilabu SA, Palacios G, Panchal RG, Park DJ, Patterson JL, Paweska JT, Peters CJ, Pettitt J, Pitt L, Radoshitzky SR, Ryabchikova EI, Saphire EO, Sabeti PC, Sealfon R, Shestopalov AM, Smither SJ, Sullivan NJ, Swanepoel R, Takada A, Towner JS, van der Groen G, Volchkov VE, Volchkova VA, Wahl-Jensen V, Warren TK, Warfield KL, Weidmann M, Nichol ST. PMID: 25256396; PMCID: PMC4189044.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    100. Structure of the LCMV nucleoprotein provides a template for understanding arenavirus replication and immunosuppression. Acta Crystallogr D Biol Crystallogr. 2014 Jun; 70(Pt 6):1764-9. West BR, Hastie KM, Saphire EO. PMID: 24914986; PMCID: PMC4051510.
      View in: PubMed   Mentions: 7     Fields:    Translation:Cells
    101. Discussions and decisions of the 2012–2014 International Committee on Taxonomy of Viruses (ICTV) Filoviridae Study Group, January 2012–June 2013. Arch Virol. 2014 Apr; 159(4):821-30. Bukreyev AA, Chandran K, Dolnik O, Dye JM, Ebihara H, Leroy EM, Mühlberger E, Netesov SV, Patterson JL, Paweska JT, Saphire EO, Smither SJ, Takada A, Towner JS, Volchkov VE, Warren TK, Kuhn JH. PMID: 24122154; PMCID: PMC3984924.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansCells
    102. Structural insights into RNA encapsidation and helical assembly of the Toscana virus nucleoprotein. Nucleic Acids Res. 2014 May; 42(9):6025-37. Olal D, Dick A, Woods VL, Liu T, Li S, Devignot S, Weber F, Saphire EO, Daumke O. PMID: 24688060; PMCID: PMC4027202.
      View in: PubMed   Mentions: 15     Fields:    Translation:Cells
    103. Structure of the Reston ebolavirus VP30 C-terminal domain. Acta Crystallogr F Struct Biol Commun. 2014 Apr; 70(Pt 4):457-60. Clifton MC, Kirchdoerfer RN, Atkins K, Abendroth J, Raymond A, Grice R, Barnes S, Moen S, Lorimer D, Edwards TE, Myler PJ, Saphire EO. PMID: 24699737; PMCID: PMC3976061.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
    104. Lassa fever in post-conflict sierra leone. PLoS Negl Trop Dis. 2014 Mar; 8(3):e2748. Shaffer JG, Grant DS, Schieffelin JS, Boisen ML, Goba A, Hartnett JN, Levy DC, Yenni RE, Moses LM, Fullah M, Momoh M, Fonnie M, Fonnie R, Kanneh L, Koroma VJ, Kargbo K, Ottomassathien D, Muncy IJ, Jones AB, Illick MM, Kulakosky PC, Haislip AM, Bishop CM, Elliot DH, Brown BL, Zhu H, Hastie KM, Andersen KG, Gire SK, Tabrizi S, Tariyal R, Stremlau M, Matschiner A, Sampey DB, Spence JS, Cross RW, Geisbert JB, Folarin OA, Happi CT, Pitts KR, Geske FJ, Geisbert TW, Saphire EO, Robinson JE, Wilson RB, Sabeti PC, Henderson LA, Khan SH, Bausch DG, Branco LM, Garry RF, Viral Hemorrhagic Fever Consortium. PMID: 24651047; PMCID: PMC3961205.
      View in: PubMed   Mentions: 89     Fields:    Translation:HumansCells
    105. Complement is activated by IgG hexamers assembled at the cell surface. Science. 2014 Mar 14; 343(6176):1260-3. Diebolder CA, Beurskens FJ, de Jong RN, Koning RI, Strumane K, Lindorfer MA, Voorhorst M, Ugurlar D, Rosati S, Heck AJ, van de Winkel JG, Wilson IA, Koster AJ, Taylor RP, Saphire EO, Burton DR, Schuurman J, Gros P, Parren PW. PMID: 24626930; PMCID: PMC4250092.
      View in: PubMed   Mentions: 206     Fields:    Translation:HumansCells
    106. Crystal structure of Marburg virus VP24. J Virol. 2014 May; 88(10):5859-63. Zhang AP, Bornholdt ZA, Abelson DM, Saphire EO. PMID: 24574400; PMCID: PMC4019143.
      View in: PubMed   Mentions: 8     Fields:    Translation:Cells
    107. Virus nomenclature below the species level: a standardized nomenclature for filovirus strains and variants rescued from cDNA. Arch Virol. 2014 May; 159(5):1229-37. Kuhn JH, Bào Y, Bavari S, Becker S, Bradfute S, Brauburger K, Rodney Brister J, Bukreyev AA, Caì Y, Chandran K, Davey RA, Dolnik O, Dye JM, Enterlein S, Gonzalez JP, Formenty P, Freiberg AN, Hensley LE, Hoenen T, Honko AN, Ignatyev GM, Jahrling PB, Johnson KM, Klenk HD, Kobinger G, Lackemeyer MG, Leroy EM, Lever MS, Mühlberger E, Netesov SV, Olinger GG, Palacios G, Patterson JL, Paweska JT, Pitt L, Radoshitzky SR, Ryabchikova EI, Saphire EO, Shestopalov AM, Smither SJ, Sullivan NJ, Swanepoel R, Takada A, Towner JS, van der Groen G, Volchkov VE, Volchkova VA, Wahl-Jensen V, Warren TK, Warfield KL, Weidmann M, Nichol ST. PMID: 24190508; PMCID: PMC4010566.
      View in: PubMed   Mentions: 32     Fields:    Translation:Cells
    108. An update on the use of antibodies against the filoviruses. Immunotherapy. 2013 Nov; 5(11):1221-33. Saphire EO. PMID: 24188676; PMCID: PMC4465755.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    109. Crystal structure of the nipah virus phosphoprotein tetramerization domain. J Virol. 2014 Jan; 88(1):758-62. Bruhn JF, Barnett KC, Bibby J, Thomas JM, Keegan RM, Rigden DJ, Bornholdt ZA, Saphire EO. PMID: 24155387; PMCID: PMC3911761.
      View in: PubMed   Mentions: 24     Fields:    Translation:Cells
    110. Structural rearrangement of ebola virus VP40 begets multiple functions in the virus life cycle. Cell. 2013 Aug 15; 154(4):763-74. Bornholdt ZA, Noda T, Abelson DM, Halfmann P, Wood MR, Kawaoka Y, Saphire EO. PMID: 23953110; PMCID: PMC4138722.
      View in: PubMed   Mentions: 86     Fields:    Translation:Cells
    111. Ebolavirus VP35 coats the backbone of double-stranded RNA for interferon antagonism. J Virol. 2013 Sep; 87(18):10385-8. Bale S, Julien JP, Bornholdt ZA, Krois AS, Wilson IA, Saphire EO. PMID: 23824825; PMCID: PMC3753998.
      View in: PubMed   Mentions: 23     Fields:    Translation:Cells
    112. Virus nomenclature below the species level: a standardized nomenclature for laboratory animal-adapted strains and variants of viruses assigned to the family Filoviridae. Arch Virol. 2013 Jun; 158(6):1425-32. Kuhn JH, Bao Y, Bavari S, Becker S, Bradfute S, Brister JR, Bukreyev AA, Caì Y, Chandran K, Davey RA, Dolnik O, Dye JM, Enterlein S, Gonzalez JP, Formenty P, Freiberg AN, Hensley LE, Honko AN, Ignatyev GM, Jahrling PB, Johnson KM, Klenk HD, Kobinger G, Lackemeyer MG, Leroy EM, Lever MS, Lofts LL, Mühlberger E, Netesov SV, Olinger GG, Palacios G, Patterson JL, Paweska JT, Pitt L, Radoshitzky SR, Ryabchikova EI, Saphire EO, Shestopalov AM, Smither SJ, Sullivan NJ, Swanepoel R, Takada A, Towner JS, van der Groen G, Volchkov VE, Wahl-Jensen V, Warren TK, Warfield KL, Weidmann M, Nichol ST. PMID: 23358612; PMCID: PMC3669655.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    113. Two synthetic antibodies that recognize and neutralize distinct proteolytic forms of the ebola virus envelope glycoprotein. Chembiochem. 2012 Nov 26; 13(17):2549-57. Koellhoffer JF, Chen G, Sandesara RG, Bale S, Saphire EO, Chandran K, Sidhu SS, Lai JR. PMID: 23111988; PMCID: PMC3684266.
      View in: PubMed   Mentions: 20     Fields:    Translation:Cells
    114. Virus nomenclature below the species level: a standardized nomenclature for natural variants of viruses assigned to the family Filoviridae. Arch Virol. 2013 Jan; 158(1):301-11. Kuhn JH, Bao Y, Bavari S, Becker S, Bradfute S, Brister JR, Bukreyev AA, Chandran K, Davey RA, Dolnik O, Dye JM, Enterlein S, Hensley LE, Honko AN, Jahrling PB, Johnson KM, Kobinger G, Leroy EM, Lever MS, Mühlberger E, Netesov SV, Olinger GG, Palacios G, Patterson JL, Paweska JT, Pitt L, Radoshitzky SR, Saphire EO, Smither SJ, Swanepoel R, Towner JS, van der Groen G, Volchkov VE, Wahl-Jensen V, Warren TK, Weidmann M, Nichol ST. PMID: 23001720; PMCID: PMC3535543.
      View in: PubMed   Mentions: 52     Fields:    Translation:HumansAnimalsCells
    115. Marburg virus VP35 can both fully coat the backbone and cap the ends of dsRNA for interferon antagonism. PLoS Pathog. 2012 Sep; 8(9):e1002916. Bale S, Julien JP, Bornholdt ZA, Kimberlin CR, Halfmann P, Zandonatti MA, Kunert J, Kroon GJ, Kawaoka Y, MacRae IJ, Wilson IA, Saphire EO. PMID: 23028316; PMCID: PMC3441732.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansCells
    116. Structural basis for the dsRNA specificity of the Lassa virus NP exonuclease. PLoS One. 2012; 7(8):e44211. Hastie KM, King LB, Zandonatti MA, Saphire EO. PMID: 22937163; PMCID: PMC3429428.
      View in: PubMed   Mentions: 24     Fields:    Translation:Cells
    117. The ebolavirus VP24 interferon antagonist: know your enemy. Virulence. 2012 Aug 15; 3(5):440-5. Zhang AP, Abelson DM, Bornholdt ZA, Liu T, Woods VL, Saphire EO. PMID: 23076242; PMCID: PMC3485981.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    118. Structural basis for differential neutralization of ebolaviruses. Viruses. 2012 04; 4(4):447-70. Bale S, Dias JM, Fusco ML, Hashiguchi T, Wong AC, Liu T, Keuhne AI, Li S, Woods VL, Chandran K, Dye JM, Saphire EO. PMID: 22590681; PMCID: PMC3347318.
      View in: PubMed   Mentions: 43     Fields:    Translation:Cells
    119. The variety of study in the field of emerging viruses. Curr Opin Virol. 2012 Apr; 2(2):157-9. Saphire EO, Feldmann H. PMID: 22482713.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    120. The ebola virus interferon antagonist VP24 directly binds STAT1 and has a novel, pyramidal fold. PLoS Pathog. 2012 Feb; 8(2):e1002550. Zhang AP, Bornholdt ZA, Liu T, Abelson DM, Lee DE, Li S, Woods VL, Saphire EO. PMID: 22383882; PMCID: PMC3285596.
      View in: PubMed   Mentions: 57     Fields:    Translation:HumansCells
    121. Hiding the evidence: two strategies for innate immune evasion by hemorrhagic fever viruses. Curr Opin Virol. 2012 Apr; 2(2):151-6. Hastie KM, Bale S, Kimberlin CR, Saphire EO. PMID: 22482712; PMCID: PMC3758253.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    122. Structure of an antibody in complex with its mucin domain linear epitope that is protective against Ebola virus. J Virol. 2012 Mar; 86(5):2809-16. Olal D, Kuehne AI, Bale S, Halfmann P, Hashiguchi T, Fusco ML, Lee JE, King LB, Kawaoka Y, Dye JM, Saphire EO. PMID: 22171276; PMCID: PMC3302272.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    123. A shared structural solution for neutralizing ebolaviruses. Nat Struct Mol Biol. 2011 Nov 20; 18(12):1424-7. Dias JM, Kuehne AI, Abelson DM, Bale S, Wong AC, Halfmann P, Muhammad MA, Fusco ML, Zak SE, Kang E, Kawaoka Y, Chandran K, Dye JM, Saphire EO. PMID: 22101933; PMCID: PMC3230659.
      View in: PubMed   Mentions: 80     Fields:    Translation:HumansAnimalsCells
    124. Ebola virus glycoprotein needs an additional trigger, beyond proteolytic priming for membrane fusion. PLoS Negl Trop Dis. 2011 Nov; 5(11):e1395. Bale S, Liu T, Li S, Wang Y, Abelson D, Fusco M, Woods VL, Saphire EO. PMID: 22102923; PMCID: PMC3216919.
      View in: PubMed   Mentions: 40     Fields:    Translation:Cells
    125. Crystal structure of the Lassa virus nucleoprotein-RNA complex reveals a gating mechanism for RNA binding. Proc Natl Acad Sci U S A. 2011 Nov 29; 108(48):19365-70. Hastie KM, Liu T, Li S, King LB, Ngo N, Zandonatti MA, Woods VL, de la Torre JC, Saphire EO. PMID: 22084115; PMCID: PMC3228486.
      View in: PubMed   Mentions: 60     Fields:    Translation:HumansCells
    126. Cathepsin cleavage potentiates the Ebola virus glycoprotein to undergo a subsequent fusion-relevant conformational change. J Virol. 2012 Jan; 86(1):364-72. Brecher M, Schornberg KL, Delos SE, Fusco ML, Saphire EO, White JM. PMID: 22031933; PMCID: PMC3255896.
      View in: PubMed   Mentions: 74     Fields:    Translation:HumansCells
    127. Measles virus fusion shifts into gear. Nat Struct Mol Biol. 2011 Feb; 18(2):115-6. Saphire EO, Oldstone MB. PMID: 21289649.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    128. Structure of the Lassa virus nucleoprotein reveals a dsRNA-specific 3' to 5' exonuclease activity essential for immune suppression. Proc Natl Acad Sci U S A. 2011 Feb 08; 108(6):2396-401. Hastie KM, Kimberlin CR, Zandonatti MA, MacRae IJ, Saphire EO. PMID: 21262835; PMCID: PMC3038715.
      View in: PubMed   Mentions: 130     Fields:    Translation:HumansCells
    129. Ebolavirus VP35 uses a bimodal strategy to bind dsRNA for innate immune suppression. Proc Natl Acad Sci U S A. 2010 Jan 05; 107(1):314-9. Kimberlin CR, Bornholdt ZA, Li S, Woods VL, MacRae IJ, Saphire EO. PMID: 20018665; PMCID: PMC2806767.
      View in: PubMed   Mentions: 65     Fields:    Translation:HumansCells
    130. Techniques and tactics used in determining the structure of the trimeric ebolavirus glycoprotein. Acta Crystallogr D Biol Crystallogr. 2009 Nov; 65(Pt 11):1162-80. Lee JE, Fusco ML, Abelson DM, Hessell AJ, Burton DR, Saphire EO. PMID: 19923712; PMCID: PMC2777170.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    131. Neutralizing ebolavirus: structural insights into the envelope glycoprotein and antibodies targeted against it. Curr Opin Struct Biol. 2009 Aug; 19(4):408-17. Lee JE, Saphire EO. PMID: 19559599; PMCID: PMC2759674.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansAnimalsCells
    132. An efficient platform for screening expression and crystallization of glycoproteins produced in human cells. Nat Protoc. 2009; 4(4):592-604. Lee JE, Fusco ML, Saphire EO. PMID: 19373230; PMCID: PMC2911120.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    133. Ebolavirus glycoprotein structure and mechanism of entry. Future Virol. 2009; 4(6):621-635. Lee JE, Saphire EO. PMID: 20198110; PMCID: PMC2829775.
      View in: PubMed   Mentions: 102  
    134. Structure of the Ebola virus glycoprotein bound to an antibody from a human survivor. Nature. 2008 Jul 10; 454(7201):177-82. Lee JE, Fusco ML, Hessell AJ, Oswald WB, Burton DR, Saphire EO. PMID: 18615077; PMCID: PMC2700032.
      View in: PubMed   Mentions: 338     Fields:    Translation:HumansAnimalsCells
    135. Complex of a protective antibody with its Ebola virus GP peptide epitope: unusual features of a V lambda x light chain. J Mol Biol. 2008 Jan 04; 375(1):202-16. Lee JE, Kuehne A, Abelson DM, Fusco ML, Hart MK, Saphire EO. PMID: 18005986; PMCID: PMC2173910.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    136. Structure of a high-affinity "mimotope" peptide bound to HIV-1-neutralizing antibody b12 explains its inability to elicit gp120 cross-reactive antibodies. J Mol Biol. 2007 Jun 08; 369(3):696-709. Saphire EO, Montero M, Menendez A, van Houten NE, Irving MB, Pantophlet R, Zwick MB, Parren PW, Burton DR, Scott JK, Wilson IA. PMID: 17445828; PMCID: PMC1995417.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    137. Ebola virus VP35 protein binds double-stranded RNA and inhibits alpha/beta interferon production induced by RIG-I signaling. J Virol. 2006 Jun; 80(11):5168-78. Cárdenas WB, Loo YM, Gale M, Hartman AL, Kimberlin CR, Martínez-Sobrido L, Saphire EO, Basler CF. PMID: 16698997; PMCID: PMC1472134.
      View in: PubMed   Mentions: 204     Fields:    Translation:HumansAnimalsCells
    138. gp41: HIV's shy protein. Nat Med. 2004 Feb; 10(2):133-4. Zwick MB, Saphire EO, Burton DR. PMID: 14760422; PMCID: PMC7095992.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    139. Molecular features of the broadly neutralizing immunoglobulin G1 b12 required for recognition of human immunodeficiency virus type 1 gp120. J Virol. 2003 May; 77(10):5863-76. Zwick MB, Parren PW, Saphire EO, Church S, Wang M, Scott JK, Dawson PE, Wilson IA, Burton DR. PMID: 12719580; PMCID: PMC154005.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansCells
    140. The carbohydrate epitope of the neutralizing anti-HIV-1 antibody 2G12. Adv Exp Med Biol. 2003; 535:205-18. Scanlan CN, Pantophlet R, Wormald MR, Saphire EO, Calarese D, Stanfield R, Wilson IA, Katinger H, Dwek RA, Burton DR, Rudd PM. PMID: 14714897.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimalsCells
    141. Crystal structure of an intact human IgG: antibody asymmetry, flexibility, and a guide for HIV-1 vaccine design. Adv Exp Med Biol. 2003; 535:55-66. Saphire EO, Stanfield RL, Crispin MD, Morris G, Zwick MB, Pantophlet RA, Parren PW, Rudd PM, Dwek RA, Burton DR, Wilson IA. PMID: 14714888.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    142. Structure-based drug design. IDrugs. 2002 Jul; 5(7):658-61. Saphire EO. PMID: 14686344.
      View in: PubMed   Mentions:    Fields:    
    143. Contrasting IgG structures reveal extreme asymmetry and flexibility. J Mol Biol. 2002 May 24; 319(1):9-18. Saphire EO, Stanfield RL, Crispin MD, Parren PW, Rudd PM, Dwek RA, Burton DR, Wilson IA. PMID: 12051932.
      View in: PubMed   Mentions: 89     Fields:    Translation:HumansAnimalsCells
    144. Broadly neutralizing antibodies targeted to the membrane-proximal external region of human immunodeficiency virus type 1 glycoprotein gp41. J Virol. 2001 Nov; 75(22):10892-905. Zwick MB, Labrijn AF, Wang M, Spenlehauer C, Saphire EO, Binley JM, Moore JP, Stiegler G, Katinger H, Burton DR, Parren PW. PMID: 11602729; PMCID: PMC114669.
      View in: PubMed   Mentions: 406     Fields:    Translation:HumansCells
    145. Listening for viral infection. Nat Biotechnol. 2001 Sep; 19(9):823-4. Saphire EO, Parren PW. PMID: 11533636.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    146. Crystal structure of a neutralizing human IGG against HIV-1: a template for vaccine design. Science. 2001 Aug 10; 293(5532):1155-9. Saphire EO, Parren PW, Pantophlet R, Zwick MB, Morris GM, Rudd PM, Dwek RA, Stanfield RL, Burton DR, Wilson IA. PMID: 11498595.
      View in: PubMed   Mentions: 322     Fields:    Translation:HumansCells
    147. A model for neutralization of viruses based on antibody coating of the virion surface. Curr Top Microbiol Immunol. 2001; 260:109-43. Burton DR, Saphire EO, Parren PW. PMID: 11443871.
      View in: PubMed   Mentions: 52     Fields:    Translation:Cells
    148. gp120: Biologic aspects of structural features. Annu Rev Immunol. 2001; 19:253-74. Poignard P, Saphire EO, Parren PW, Burton DR. PMID: 11244037.
      View in: PubMed   Mentions: 89     Fields:    Translation:HumansCells
    149. Crystallization and preliminary structure determination of an intact human immunoglobulin, b12: an antibody that broadly neutralizes primary isolates of HIV-1. Acta Crystallogr D Biol Crystallogr. 2001 Jan; 57(Pt 1):168-71. Saphire EO, Parren PW, Barbas CF, Burton DR, Wilson IA. PMID: 11134947.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
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