Mark Ginsberg

Title(s)Distinguished Professor, Medicine
SchoolHealth Sciences
Address9500 Gilman Drive #0726
La Jolla CA 92093
Phone858-822-6432
vCardDownload vCard

    Collapse Overview 
    Collapse Overview
    Dr. Mark H. Ginsberg is a professor of medicine and director of the Physician-Scientist Training Pathway at UC San Diego. Dr. Ginsberg moved his research laboratory from the Scripps Research Institute to the Department of Medicine at the University of California, San Diego in July 2004.

    Research Interests
    Molecular structure and function of integrins in immune responses.

    Education and Training
    Psychology - McGill University, Montreal, Canada - 1965
    MD (Summa cum laude) - State University of NY - 1970
    Intern/Resident - University of Chicago - 1970-1973
    Rheumatology Fellow - University of Chicago - 1973-1975

    Collapse Research 
    Collapse Research Activities and Funding
    Cellular Mechanisms of Inflammation, Hemostasis, and Thrombosis
    NIH P01HL151433Aug 5, 2020 - Jul 31, 2025
    Role: Principal Investigator
    Deconvoluting the Vascular Adhesome
    NIH R35HL139947Jan 1, 2018 - Dec 31, 2024
    Role: Principal Investigator
    Signaling Aberrations and Cerebral Cavernous Malformation Pathogenesis
    NIH P01NS092521Sep 1, 2015 - Jun 30, 2020
    Role: Co-Investigator
    Tilting the Balance of Integrin Activation
    NIH/NHLBI R01HL126844Apr 2, 2015 - Mar 31, 2019
    Role: Principal Investigator
    Composition and Functions of the Integrin Activation Complex
    NIH R01HL117807May 1, 2014 - Apr 30, 2018
    Role: Principal Investigator
    KRIT1 and Vascular Integrity
    NIH R01HL106489Jan 3, 2011 - Dec 31, 2017
    Role: Principal Investigator
    Assembly, dynamics and evolution of cell-cell and cell-matrix adhesions
    NIH U01GM094663Sep 30, 2010 - Jun 30, 2015
    Role: Co-Investigator
    Assay Development for HT Molecular Screening for Inhibitors of Integrin Signaling
    NIH R21NS059433Sep 30, 2007 - Aug 31, 2008
    Role: Principal Investigator
    alpha4beta1 Intergrin Signaling In Immunity And Arthritis
    NIH R01AR052367Jul 1, 2007 - May 31, 2012
    Role: Principal Investigator
    Blood Cells in Hemostasis and Thrombosis
    NIH T32HL086344Jan 1, 2007 - May 30, 2024
    Role: Principal Investigator
    Regulation of Fibronectin Matrix Assembly
    NIH R01HL080529Apr 1, 2005 - Aug 31, 2005
    Role: Principal Investigator
    Cell Adhesion Mechanisms in Vascular Disease & Thrombosis
    NIH P01HL078784Dec 1, 2004 - Apr 30, 2021
    Role: Principal Investigator
    A Proteomics Research Resource for Integrative Biology
    NIH P41RR018522Sep 15, 2003 - Jun 30, 2013
    Role: Co-Investigator
    Cytoplasmic Regulation of a4b1 Avidity under Flow
    NIH R03TW006425Jul 1, 2003 - Jun 30, 2007
    Role: Principal Investigator
    Cell Migration Consortium
    NIH U54GM064346Sep 15, 2001 - Jul 31, 2014
    Role: Co-Investigator
    Integrin Signaling in Hemostasis and Blood Diseases
    NIH P01HL057900Apr 1, 1997 - Jan 31, 2014
    Role: Co-Investigator
    Thrombus Formation and Antithrombotic Intervention
    NIH P01HL031950Dec 1, 1996 - Jun 30, 2017
    Role: Co-Investigator
    GORDON CONFERENCE--FIBRONECTIN AND MACROMOLECULES
    NIH R13HL049091Feb 1, 1993 - Jan 31, 1994
    Role: Principal Investigator
    CELL ADHESION MECHANISMS IN VASCULAR DISEASE
    NIH P01HL048728Sep 30, 1992 - Aug 31, 2004
    Role: Principal Investigator
    VASCULAR BIOLOGY, THROMBOSIS, AND HEMOSTASIS
    NIH T32HL007695Jul 1, 1991 - Jun 30, 2007
    Role: Principal Investigator
    FIBRONECTIN AND PLATELETS
    NIH R01HL028235Jan 1, 1982 - Jun 30, 1996
    Role: Principal Investigator
    Regulation of Integrin Alpha4 Betal
    NIH R01AR027214Aug 1, 1980 - Nov 30, 2011
    Role: Principal Investigator
    PLATELETS IN RHEUMATIC DISEASE
    NIH R37AR027214Aug 1, 1980 - Jan 31, 2001
    Role: Principal Investigator
    GENERAL CLINICAL RESEARCH CENTER
    NIH M01RR000833Dec 1, 1977 - Sep 30, 2005
    Role: Co-Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Cerebral Cavernous Malformation: From Mechanism to Therapy. Circ Res. 2021 06 25; 129(1):195-215. Snellings DA, Hong CC, Ren AA, Lopez-Ramirez MA, Girard R, Srinath A, Marchuk DA, Ginsberg MH, Awad IA, Kahn ML. PMID: 34166073.
      View in: PubMed   Mentions: 1     Fields:    
    2. Astrocytes propel neurovascular dysfunction during cerebral cavernous malformation lesion formation. J Clin Invest. 2021 May 27. Lopez-Ramirez MA, Lai CC, Soliman SI, Hale P, Pham A, Estrada EJ, McCurdy S, Girard R, Verma R, Moore T, Lightle R, Hobson N, Shenkar R, Poulsen O, Haddad GG, Daneman R, Gongol B, Sun H, Lagarrigue F, Awad IA, Ginsberg MH. PMID: 34043589.
      View in: PubMed   Mentions:    Fields:    
    3. Abortive intussusceptive angiogenesis causes multi-cavernous vascular malformations. Elife. 2021 May 20; 10. Li W, Tran V, Shaked I, Xue B, Moore T, Lightle R, Kleinfeld D, Awad IA, Ginsberg MH. PMID: 34013885.
      View in: PubMed   Mentions:    Fields:    
    4. Optogenetic-based Localization of Talin to the Plasma Membrane Promotes Activation of ß3 Integrins. J Biol Chem. 2021 Apr 15; 100675. Liao Z, Gingras AR, Lagarrigue F, Ginsberg MH, Shattil SJ. PMID: 33865854.
      View in: PubMed   Mentions:    Fields:    
    5. Endothelial struts enable the generation of large lumenized blood vessels de novo. Nat Cell Biol. 2021 Apr; 23(4):322-329. Weijts B, Shaked I, Ginsberg M, Kleinfeld D, Robin C, Traver D. PMID: 33837285.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    6. Propranolol inhibits cavernous vascular malformations by ß1 adrenergic receptor antagonism in animal models. J Clin Invest. 2021 Feb 01; 131(3). Li W, Shenkar R, Detter MR, Moore T, Benavides C, Lightle R, Girard R, Hobson N, Cao Y, Li Y, Griffin E, Gallione C, Zabramski JM, Ginsberg MH, Marchuk DA, Awad IA. PMID: 33301422.
      View in: PubMed   Mentions: 2     Fields:    
    7. Distinct integrin activation pathways for effector and regulatory T cell trafficking and function. J Exp Med. 2021 Feb 01; 218(2). Sun H, Lagarrigue F, Wang H, Fan Z, Lopez-Ramirez MA, Chang JT, Ginsberg MH. PMID: 33104169.
      View in: PubMed   Mentions: 1     Fields:    
    8. Kindlin-3 recruitment to the plasma membrane precedes high-affinity ß2-integrin and neutrophil arrest from rolling. Blood. 2021 01 07; 137(1):29-38. Wen L, Marki A, Roy P, McArdle S, Sun H, Fan Z, Gingras AR, Ginsberg MH, Ley K. PMID: 32777822.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    9. A stem cell reporter based platform to identify and target drug resistant stem cells in myeloid leukemia. Nat Commun. 2020 11 26; 11(1):5998. Spinler K, Bajaj J, Ito T, Zimdahl B, Hamilton M, Ahmadi A, Koechlein CS, Lytle N, Kwon HY, Anower-E-Khuda F, Sun H, Blevins A, Weeks J, Kritzik M, Karlseder J, Ginsberg MH, Park PW, Esko JD, Reya T. PMID: 33243988.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    10. MARCH Proteins Mediate Responses to Antitumor Antibodies. J Immunol. 2020 11 15; 205(10):2883-2892. Ablack JN, Ortiz J, Bajaj J, Trinh K, Lagarrigue F, Cantor JM, Reya T, Ginsberg MH. PMID: 33077644.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    11. Talin-1 is the principal platelet Rap1 effector of integrin activation. Blood. 2020 09 03; 136(10):1180-1190. Lagarrigue F, Paul DS, Gingras AR, Valadez AJ, Sun H, Lin J, Cuevas MN, Ablack JN, Lopez-Ramirez MA, Bergmeier W, Ginsberg MH. PMID: 32518959.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    12. Signal Transduction: Physical Deformation of the Membrane Activates Integrins. Curr Biol. 2020 05 04; 30(9):R397-R400. Gingras AR, Ginsberg MH. PMID: 32369751.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    13. ß7 Integrin Inhibition Can Increase Intestinal Inflammation by Impairing Homing of CD25hiFoxP3+ Regulatory T Cells. Cell Mol Gastroenterol Hepatol. 2020; 9(3):369-385. Sun H, Kuk W, Rivera-Nieves J, Lopez-Ramirez MA, Eckmann L, Ginsberg MH. PMID: 31707128.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    14. Frontline Science: A flexible kink in the transmembrane domain impairs ß2 integrin extension and cell arrest from rolling. J Leukoc Biol. 2020 02; 107(2):175-183. Sun H, Fan Z, Gingras AR, Lopez-Ramirez MA, Ginsberg MH, Ley K. PMID: 31475386.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    15. Transcriptome clarifies mechanisms of lesion genesis versus progression in models of Ccm3 cerebral cavernous malformations. Acta Neuropathol Commun. 2019 08 19; 7(1):132. Koskimäki J, Zhang D, Li Y, Saadat L, Moore T, Lightle R, Polster SP, Carrión-Penagos J, Lyne SB, Zeineddine HA, Shi C, Shenkar R, Romanos S, Avner K, Srinath A, Shen L, Detter MR, Snellings D, Cao Y, Lopez-Ramirez MA, Fonseca G, Tang AT, Faber P, Andrade J, Ginsberg M, Kahn ML, Marchuk DA, Girard R, Awad IA. PMID: 31426861.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    16. Biomarkers of cavernous angioma with symptomatic hemorrhage. JCI Insight. 2019 06 20; 4(12). Lyne SB, Girard R, Koskimäki J, Zeineddine HA, Zhang D, Cao Y, Li Y, Stadnik A, Moore T, Lightle R, Shi C, Shenkar R, Carrión-Penagos J, Polster SP, Romanos S, Akers A, Lopez-Ramirez M, Whitehead KJ, Kahn ML, Ginsberg MH, Marchuk DA, Awad IA. PMID: 31217347.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    17. Rap1 binding and a lipid-dependent helix in talin F1 domain promote integrin activation in tandem. J Cell Biol. 2019 06 03; 218(6):1799-1809. Gingras AR, Lagarrigue F, Cuevas MN, Valadez AJ, Zorovich M, McLaughlin W, Lopez-Ramirez MA, Seban N, Ley K, Kiosses WB, Ginsberg MH. PMID: 30988001.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    18. Comprehensive transcriptome analysis of cerebral cavernous malformation across multiple species and genotypes. JCI Insight. 2019 Feb 07; 4(3). Koskimäki J, Girard R, Li Y, Saadat L, Zeineddine HA, Lightle R, Moore T, Lyne S, Avner K, Shenkar R, Cao Y, Shi C, Polster SP, Zhang D, Carrión-Penagos J, Romanos S, Fonseca G, Lopez-Ramirez MA, Chapman EM, Popiel E, Tang AT, Akers A, Faber P, Andrade J, Ginsberg M, Derry WB, Kahn ML, Marchuk DA, Awad IA. PMID: 30728328.
      View in: PubMed   Mentions: 11     Fields:    
    19. High-Affinity Bent ß2-Integrin Molecules in Arresting Neutrophils Face Each Other through Binding to ICAMs In cis. Cell Rep. 2019 01 02; 26(1):119-130.e5. Fan Z, Kiosses WB, Sun H, Orecchioni M, Ghosheh Y, Zajonc DM, Arnaout MA, Gutierrez E, Groisman A, Ginsberg MH, Ley K. PMID: 30605669.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    20. Cerebral cavernous malformations form an anticoagulant vascular domain in humans and mice. Blood. 2019 01 17; 133(3):193-204. Lopez-Ramirez MA, Pham A, Girard R, Wyseure T, Hale P, Yamashita A, Koskimäki J, Polster S, Saadat L, Romero IA, Esmon CT, Lagarrigue F, Awad IA, Mosnier LO, Ginsberg MH. PMID: 30442679.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    21. Rap1 binding to the talin 1 F0 domain makes a minimal contribution to murine platelet GPIIb-IIIa activation. Blood Adv. 2018 09 25; 2(18):2358-2368. Lagarrigue F, Gingras AR, Paul DS, Valadez AJ, Cuevas MN, Sun H, Lopez-Ramirez MA, Goult BT, Shattil SJ, Bergmeier W, Ginsberg MH. PMID: 30242097.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    22. Phenotypic characterization of murine models of cerebral cavernous malformations. Lab Invest. 2019 03; 99(3):319-330. Zeineddine HA, Girard R, Saadat L, Shen L, Lightle R, Moore T, Cao Y, Hobson N, Shenkar R, Avner K, Chaudager K, Koskimäki J, Polster SP, Fam MD, Shi C, Lopez-Ramirez MA, Tang AT, Gallione C, Kahn ML, Ginsberg M, Marchuk DA, Awad IA. PMID: 29946133.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    23. Integrin Activation Controls Regulatory T Cell-Mediated Peripheral Tolerance. J Immunol. 2018 06 15; 200(12):4012-4023. Klann JE, Kim SH, Remedios KA, He Z, Metz PJ, Lopez J, Tysl T, Olvera JG, Ablack JN, Cantor JM, Boland BS, Yeo G, Zheng Y, Lu LF, Bui JD, Ginsberg MH, Petrich BG, Chang JT. PMID: 29703862.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    24. Transmission of integrin ß7 transmembrane domain topology enables gut lymphoid tissue development. J Cell Biol. 2018 04 02; 217(4):1453-1465. Sun H, Lagarrigue F, Gingras AR, Fan Z, Ley K, Ginsberg MH. PMID: 29535192.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    25. The Therapeutic Antibody LM609 Selectively Inhibits Ligand Binding to Human aVß3 Integrin via Steric Hindrance. Structure. 2017 11 07; 25(11):1732-1739.e5. Borst AJ, James ZM, Zagotta WN, Ginsberg M, Rey FA, DiMaio F, Backovic M, Veesler D. PMID: 29033288.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    26. Thrombospondin1 (TSP1) replacement prevents cerebral cavernous malformations. J Exp Med. 2017 Nov 06; 214(11):3331-3346. Lopez-Ramirez MA, Fonseca G, Zeineddine HA, Girard R, Moore T, Pham A, Cao Y, Shenkar R, de Kreuk BJ, Lagarrigue F, Lawler J, Glass CK, Awad IA, Ginsberg MH. PMID: 28970240.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
    27. Talin Plays a Critical Role in the Maintenance of the Regulatory T Cell Pool. J Immunol. 2017 06 15; 198(12):4639-4651. Klann JE, Remedios KA, Kim SH, Metz PJ, Lopez J, Mack LA, Zheng Y, Ginsberg MH, Petrich BG, Chang JT. PMID: 28515282.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    28. Tissue Factor Prothrombotic Activity Is Regulated by Integrin-arf6 Trafficking. Arterioscler Thromb Vasc Biol. 2017 07; 37(7):1323-1331. Rothmeier AS, Marchese P, Langer F, Kamikubo Y, Schaffner F, Cantor J, Ginsberg MH, Ruggeri ZM, Ruf W. PMID: 28495929.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    29. Epigallocatechin gallate has pleiotropic effects on transmembrane signaling by altering the embedding of transmembrane domains. J Biol Chem. 2017 06 16; 292(24):9858-9864. Ye F, Yang C, Kim J, MacNevin CJ, Hahn KM, Park D, Ginsberg MH, Kim C. PMID: 28487468.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    30. Cutting Edge: Loss of T Cell RIAM Precludes Conjugate Formation with APC and Prevents Immune-Mediated Diabetes. J Immunol. 2017 05 01; 198(9):3410-3415. Lagarrigue F, Gertler FB, Ginsberg MH, Cantor JM. PMID: 28348273.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    31. CD98 regulates vascular smooth muscle cell proliferation in atherosclerosis. Atherosclerosis. 2017 01; 256:105-114. Baumer Y, McCurdy S, Alcala M, Mehta N, Lee BH, Ginsberg MH, Boisvert WA. PMID: 28012647.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    32. Structural Basis of Dimeric Rasip1 RA Domain Recognition of the Ras Subfamily of GTP-Binding Proteins. Structure. 2016 12 06; 24(12):2152-2162. Gingras AR, Puzon-McLaughlin W, Bobkov AA, Ginsberg MH. PMID: 27839947.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    33. CD98-Mediated Adhesive Signaling Enables the Establishment and Propagation of Acute Myelogenous Leukemia. Cancer Cell. 2016 Nov 14; 30(5):792-805. Bajaj J, Konuma T, Lytle NK, Kwon HY, Ablack JN, Cantor JM, Rizzieri D, Chuah C, Oehler VG, Broome EH, Ball ED, van der Horst EH, Ginsberg MH, Reya T. PMID: 27908736.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    34. Neutrophil recruitment limited by high-affinity bent ß2 integrin binding ligand in cis. Nat Commun. 2016 08 31; 7:12658. Fan Z, McArdle S, Marki A, Mikulski Z, Gutierrez E, Engelhardt B, Deutsch U, Ginsberg M, Groisman A, Ley K. PMID: 27578049.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    35. Enhanced Integrin a4ß1-Mediated Adhesion Contributes to a Mobilization Defect of Endothelial Progenitor Cells in Diabetes. Diabetes. 2016 Nov; 65(11):3505-3515. Abplanalp WT, Conklin DJ, Cantor JM, Ginsberg MH, Wysoczynski M, Bhatnagar A, O'Toole TE. PMID: 27495221.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    36. A Conserved Ectodomain-Transmembrane Domain Linker Motif Tunes the Allosteric Regulation of Cell Surface Receptors. J Biol Chem. 2016 08 19; 291(34):17536-46. Schmidt T, Ye F, Situ AJ, An W, Ginsberg MH, Ulmer TS. PMID: 27365391.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    37. The Rap1-RIAM-talin axis of integrin activation and blood cell function. Blood. 2016 07 28; 128(4):479-87. Lagarrigue F, Kim C, Ginsberg MH. PMID: 27207789.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansCells
    38. Amino Acid Transport Associated to Cluster of Differentiation 98 Heavy Chain (CD98hc) Is at the Cross-road of Oxidative Stress and Amino Acid Availability. J Biol Chem. 2016 Apr 29; 291(18):9700-11. de la Ballina LR, Cano-Crespo S, González-Muñoz E, Bial S, Estrach S, Cailleteau L, Tissot F, Daniel H, Zorzano A, Ginsberg MH, Palacín M, Féral CC. PMID: 26945935.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    39. Heart of glass anchors Rasip1 at endothelial cell-cell junctions to support vascular integrity. Elife. 2016 Jan 19; 5:e11394. de Kreuk BJ, Gingras AR, Knight JD, Liu JJ, Gingras AC, Ginsberg MH. PMID: 26780829.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    40. Ubiquitylation of CD98 limits cell proliferation and clonal expansion. J Cell Sci. 2015 Dec 01; 128(23):4273-8. Ablack JN, Metz PJ, Chang JT, Cantor JM, Ginsberg MH. PMID: 26493331.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    41. RLIP76 regulates Arf6-dependent cell spreading and migration by linking ARNO with activated R-Ras at recycling endosomes. Biochem Biophys Res Commun. 2015 Nov 27; 467(4):785-91. Wurtzel JG, Lee S, Singhal SS, Awasthi S, Ginsberg MH, Goldfinger LE. PMID: 26498519.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    42. A RIAM/lamellipodin-talin-integrin complex forms the tip of sticky fingers that guide cell migration. Nat Commun. 2015 Sep 30; 6:8492. Lagarrigue F, Vikas Anekal P, Lee HS, Bachir AI, Ablack JN, Horwitz AF, Ginsberg MH. PMID: 26419705.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCells
    43. The Structure of a Full-length Membrane-embedded Integrin Bound to a Physiological Ligand. J Biol Chem. 2015 Nov 06; 290(45):27168-27175. Dai A, Ye F, Taylor DW, Hu G, Ginsberg MH, Taylor KA. PMID: 26391523.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    44. An Isoform-Specific Myristylation Switch Targets Type II PKA Holoenzymes to Membranes. Structure. 2015 Sep 01; 23(9):1563-1572. Zhang P, Ye F, Bastidas AC, Kornev AP, Wu J, Ginsberg MH, Taylor SS. PMID: 26278174.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    45. Blocking neutrophil integrin activation prevents ischemia-reperfusion injury. J Exp Med. 2015 Jul 27; 212(8):1267-81. Yago T, Petrich BG, Zhang N, Liu Z, Shao B, Ginsberg MH, McEver RP. PMID: 26169939.
      View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
    46. Caspase-1-mediated pathway promotes generation of thromboinflammatory microparticles. J Clin Invest. 2015 Apr; 125(4):1471-84. Rothmeier AS, Marchese P, Petrich BG, Furlan-Freguia C, Ginsberg MH, Ruggeri ZM, Ruf W. PMID: 25705884.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
    47. Annular anionic lipids stabilize the integrin aIIbß3 transmembrane complex. J Biol Chem. 2015 Mar 27; 290(13):8283-93. Schmidt T, Suk JE, Ye F, Situ AJ, Mazumder P, Ginsberg MH, Ulmer TS. PMID: 25632962.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    48. Fine-tuning Tumor Immunity with Integrin Trans-regulation. Cancer Immunol Res. 2015 Jun; 3(6):661-7. Cantor JM, Rose DM, Slepak M, Ginsberg MH. PMID: 25600437.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    49. Antitumor activity of an anti-CD98 antibody. Int J Cancer. 2015 Aug 01; 137(3):710-20. Hayes GM, Chinn L, Cantor JM, Cairns B, Levashova Z, Tran H, Velilla T, Duey D, Lippincott J, Zachwieja J, Ginsberg MH, H van der Horst E. PMID: 25556716.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    50. Interaction of kindlin-2 with integrin ß3 promotes outside-in signaling responses by the aVß3 vitronectin receptor. Blood. 2015 Mar 19; 125(12):1995-2004. Liao Z, Kato H, Pandey M, Cantor JM, Ablooglu AJ, Ginsberg MH, Shattil SJ. PMID: 25587038.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    51. Integrin activation. BMB Rep. 2014 Dec; 47(12):655-9. Ginsberg MH. PMID: 25388208.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansCells
    52. CD98hc (SLC3A2) loss protects against ras-driven tumorigenesis by modulating integrin-mediated mechanotransduction. Cancer Res. 2014 Dec 01; 74(23):6878-89. Estrach S, Lee SA, Boulter E, Pisano S, Errante A, Tissot FS, Cailleteau L, Pons C, Ginsberg MH, Féral CC. PMID: 25267066.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    53. SnapShot: talin and the modular nature of the integrin adhesome. Cell. 2014 Mar 13; 156(6):1340-1340.e1. Ye F, Lagarrigue F, Ginsberg MH. PMID: 24630731.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    54. ADAP interactions with talin and kindlin promote platelet integrin aIIbß3 activation and stable fibrinogen binding. Blood. 2014 May 15; 123(20):3156-65. Kasirer-Friede A, Kang J, Kahner B, Ye F, Ginsberg MH, Shattil SJ. PMID: 24523237.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    55. Talin and kindlin: the one-two punch in integrin activation. Front Med. 2014 Mar; 8(1):6-16. Ye F, Snider AK, Ginsberg MH. PMID: 24477625.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansAnimalsCells
    56. High mutation detection rates in cerebral cavernous malformation upon stringent inclusion criteria: one-third of probands are minors. Mol Genet Genomic Med. 2014 Mar; 2(2):176-85. Spiegler S, Najm J, Liu J, Gkalympoudis S, Schröder W, Borck G, Brockmann K, Elbracht M, Fauth C, Ferbert A, Freudenberg L, Grasshoff U, Hellenbroich Y, Henn W, Hoffjan S, Hüning I, Korenke GC, Kroisel PM, Kunstmann E, Mair M, Munk-Schulenburg S, Nikoubashman O, Pauli S, Rudnik-Schöneborn S, Sudholt I, Sure U, Tinschert S, Wiednig M, Zoll B, Ginsberg MH, Felbor U. PMID: 24689081.
      View in: PubMed   Mentions: 22     Fields:    
    57. Sleeve lobectomy for non-small cell lung cancer with N1 nodal disease does not compromise survival. Ann Thorac Surg. 2014 Jan; 97(1):230-5. Berry MF, Worni M, Wang X, Harpole DH, D'Amico TA, Onaitis MW. PMID: 24210614.
      View in: PubMed   Mentions: 62     Fields:    Translation:HumansAnimalsCells
    58. The nucleus of endothelial cell as a sensor of blood flow direction. Biol Open. 2013; 2(10):1007-12. Tkachenko E, Gutierrez E, Saikin SK, Fogelstrand P, Kim C, Groisman A, Ginsberg MH. PMID: 24167710.
      View in: PubMed   Mentions:
    59. The structure of the ternary complex of Krev interaction trapped 1 (KRIT1) bound to both the Rap1 GTPase and the heart of glass (HEG1) cytoplasmic tail. J Biol Chem. 2013 Aug 16; 288(33):23639-49. Gingras AR, Puzon-McLaughlin W, Ginsberg MH. PMID: 23814056.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    60. Two modes of integrin activation form a binary molecular switch in adhesion maturation. Mol Biol Cell. 2013 May; 24(9):1354-62. Lee HS, Anekal P, Lim CJ, Liu CC, Ginsberg MH. PMID: 23468527.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimalsCells
    61. Reconstructing integrin activation in vitro. Methods Mol Biol. 2013; 1046:1-17. Gingras AR, Ye F, Ginsberg MH. PMID: 23868579.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    62. Talin1 and Rap1 are critical for osteoclast function. Mol Cell Biol. 2013 Feb; 33(4):830-44. Zou W, Izawa T, Zhu T, Chappel J, Otero K, Monkley SJ, Critchley DR, Petrich BG, Morozov A, Ginsberg MH, Teitelbaum SL. PMID: 23230271.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    63. Tiam1 interaction with the PAR complex promotes talin-mediated Rac1 activation during polarized cell migration. J Cell Biol. 2012 Oct 15; 199(2):331-45. Wang S, Watanabe T, Matsuzawa K, Katsumi A, Kakeno M, Matsui T, Ye F, Sato K, Murase K, Sugiyama I, Kimura K, Mizoguchi A, Ginsberg MH, Collard JG, Kaibuchi K. PMID: 23071154.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimalsCells
    64. Structural basis of the junctional anchorage of the cerebral cavernous malformations complex. J Cell Biol. 2012 Oct 01; 199(1):39-48. Gingras AR, Liu JJ, Ginsberg MH. PMID: 23007647.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimalsCells
    65. Talin activates integrins by altering the topology of the ß transmembrane domain. J Cell Biol. 2012 May 28; 197(5):605-11. Kim C, Ye F, Hu X, Ginsberg MH. PMID: 22641344.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansAnimalsCells
    66. Kindlins, integrin activation and the regulation of talin recruitment to aIIbß3. PLoS One. 2012; 7(3):e34056. Kahner BN, Kato H, Banno A, Ginsberg MH, Shattil SJ, Ye F. PMID: 22457811.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    67. Distinct roles for talin-1 and kindlin-3 in LFA-1 extension and affinity regulation. Blood. 2012 May 03; 119(18):4275-82. Lefort CT, Rossaint J, Moser M, Petrich BG, Zarbock A, Monkley SJ, Critchley DR, Ginsberg MH, Fässler R, Ley K. PMID: 22431571.
      View in: PubMed   Mentions: 99     Fields:    Translation:HumansAnimalsCells
    68. CD98 at the crossroads of adaptive immunity and cancer. J Cell Sci. 2012 Mar 15; 125(Pt 6):1373-82. Cantor JM, Ginsberg MH. PMID: 22499670.
      View in: PubMed   Mentions: 71     Fields:    Translation:HumansAnimalsCells
    69. Subcellular localization of talin is regulated by inter-domain interactions. J Biol Chem. 2012 Apr 20; 287(17):13799-812. Banno A, Goult BT, Lee H, Bate N, Critchley DR, Ginsberg MH. PMID: 22351767.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    70. Basic amino-acid side chains regulate transmembrane integrin signalling. Nature. 2011 Dec 18; 481(7380):209-13. Kim C, Schmidt T, Cho EG, Ye F, Ulmer TS, Ginsberg MH. PMID: 22178926.
      View in: PubMed   Mentions: 58     Fields:    Translation:AnimalsCells
    71. Phosphorylation sites in the cerebral cavernous malformations complex. J Cell Sci. 2011 Dec 01; 124(Pt 23):3929-32. Kim J, Sherman NE, Fox JW, Ginsberg MH. PMID: 22194303.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    72. Fasudil decreases lesion burden in a murine model of cerebral cavernous malformation disease. Stroke. 2012 Feb; 43(2):571-4. McDonald DA, Shi C, Shenkar R, Stockton RA, Liu F, Ginsberg MH, Marchuk DA, Awad IA. PMID: 22034008.
      View in: PubMed   Mentions: 49     Fields:    Translation:Animals
    73. High refractive index silicone gels for simultaneous total internal reflection fluorescence and traction force microscopy of adherent cells. PLoS One. 2011; 6(9):e23807. Gutierrez E, Tkachenko E, Besser A, Sundd P, Ley K, Danuser G, Ginsberg MH, Groisman A. PMID: 21961031.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    74. Reconstruction of integrin activation. Blood. 2012 Jan 05; 119(1):26-33. Ye F, Kim C, Ginsberg MH. PMID: 21921044.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansCells
    75. Molecular mechanism of inside-out integrin regulation. J Thromb Haemost. 2011 Jul; 9 Suppl 1:20-25. Ye F, Kim C, Ginsberg MH. PMID: 21781238.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCells
    76. Live cell imaging of paxillin in rolling neutrophils by dual-color quantitative dynamic footprinting. Microcirculation. 2011 Jul; 18(5):361-72. Sundd P, Gutierrez E, Petrich BG, Ginsberg MH, Groisman A, Ley K. PMID: 21418380.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    77. Receptor tyrosine kinases and TLR/IL1Rs unexpectedly activate myeloid cell PI3k?, a single convergent point promoting tumor inflammation and progression. Cancer Cell. 2011 Jun 14; 19(6):715-27. Schmid MC, Avraamides CJ, Dippold HC, Franco I, Foubert P, Ellies LG, Acevedo LM, Manglicmot JR, Song X, Wrasidlo W, Blair SL, Ginsberg MH, Cheresh DA, Hirsch E, Field SJ, Varner JA. PMID: 21665146.
      View in: PubMed   Mentions: 147     Fields:    Translation:HumansAnimals
    78. Loss of T cell CD98 H chain specifically ablates T cell clonal expansion and protects from autoimmunity. J Immunol. 2011 Jul 15; 187(2):851-60. Cantor J, Slepak M, Ege N, Chang JT, Ginsberg MH. PMID: 21670318.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    79. Regulation of integrin activation. Annu Rev Cell Dev Biol. 2011; 27:321-45. Kim C, Ye F, Ginsberg MH. PMID: 21663444.
      View in: PubMed   Mentions: 171     Fields:    Translation:HumansAnimalsCells
    80. A mechanism of Rap1-induced stabilization of endothelial cell--cell junctions. Mol Biol Cell. 2011 Jul 15; 22(14):2509-19. Liu JJ, Stockton RA, Gingras AR, Ablooglu AJ, Han J, Bobkov AA, Ginsberg MH. PMID: 21633110.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimalsCells
    81. Protein kinase A governs a RhoA-RhoGDI protrusion-retraction pacemaker in migrating cells. Nat Cell Biol. 2011 Jun; 13(6):660-7. Tkachenko E, Sabouri-Ghomi M, Pertz O, Kim C, Gutierrez E, Machacek M, Groisman A, Danuser G, Ginsberg MH. PMID: 21572420.
      View in: PubMed   Mentions: 75     Fields:    Translation:AnimalsCells
    82. Abl-interactor-1 (Abi1) has a role in cardiovascular and placental development and is a binding partner of the alpha4 integrin. Proc Natl Acad Sci U S A. 2011 Jan 04; 108(1):149-54. Ring C, Ginsberg MH, Haling J, Pendergast AM. PMID: 21173240.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    83. Endothelial cell talin1 is essential for embryonic angiogenesis. Dev Biol. 2011 Jan 15; 349(2):494-502. Monkley SJ, Kostourou V, Spence L, Petrich B, Coleman S, Ginsberg MH, Pritchard CA, Critchley DR. PMID: 21081121.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    84. A novel mouse model of cerebral cavernous malformations based on the two-hit mutation hypothesis recapitulates the human disease. Hum Mol Genet. 2011 Jan 15; 20(2):211-22. McDonald DA, Shenkar R, Shi C, Stockton RA, Akers AL, Kucherlapati MH, Kucherlapati R, Brainer J, Ginsberg MH, Awad IA, Marchuk DA. PMID: 20940147.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansAnimalsCells
    85. Integrin alpha4beta1 signaling is required for lymphangiogenesis and tumor metastasis. Cancer Res. 2010 Apr 15; 70(8):3042-51. Garmy-Susini B, Avraamides CJ, Schmid MC, Foubert P, Ellies LG, Barnes L, Feral C, Papayannopoulou T, Lowy A, Blair SL, Cheresh D, Ginsberg M, Varner JA. PMID: 20388801.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansAnimalsCells
    86. The final steps of integrin activation: the end game. Nat Rev Mol Cell Biol. 2010 Apr; 11(4):288-300. Shattil SJ, Kim C, Ginsberg MH. PMID: 20308986.
      View in: PubMed   Mentions: 364     Fields:    Translation:HumansAnimalsCells
    87. Cerebral cavernous malformations proteins inhibit Rho kinase to stabilize vascular integrity. J Exp Med. 2010 Apr 12; 207(4):881-96. Stockton RA, Shenkar R, Awad IA, Ginsberg MH. PMID: 20308363.
      View in: PubMed   Mentions: 134     Fields:    Translation:HumansAnimalsCells
    88. A small molecule that inhibits the interaction of paxillin and alpha 4 integrin inhibits accumulation of mononuclear leukocytes at a site of inflammation. J Biol Chem. 2010 Mar 26; 285(13):9462-9469. Kummer C, Petrich BG, Rose DM, Ginsberg MH. PMID: 20097761.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    89. Recreation of the terminal events in physiological integrin activation. J Cell Biol. 2010 Jan 11; 188(1):157-73. Ye F, Hu G, Taylor D, Ratnikov B, Bobkov AA, McLean MA, Sligar SG, Taylor KA, Ginsberg MH. PMID: 20048261.
      View in: PubMed   Mentions: 129     Fields:    Translation:HumansAnimalsCells
    90. Phosphoprotein enriched in astrocytes 15 kDa (PEA-15) reprograms growth factor signaling by inhibiting threonine phosphorylation of fibroblast receptor substrate 2alpha. Mol Biol Cell. 2010 Feb 15; 21(4):664-73. Haling JR, Wang F, Ginsberg MH. PMID: 20032303.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    91. Rap1 and its effector KRIT1/CCM1 regulate beta-catenin signaling. Dis Model Mech. 2010 Jan-Feb; 3(1-2):73-83. Glading AJ, Ginsberg MH. PMID: 20007487.
      View in: PubMed   Mentions: 53     Fields:    Translation:HumansAnimalsCells
    92. Beta integrin tyrosine phosphorylation is a conserved mechanism for regulating talin-induced integrin activation. J Biol Chem. 2009 Dec 25; 284(52):36700-36710. Anthis NJ, Haling JR, Oxley CL, Memo M, Wegener KL, Lim CJ, Ginsberg MH, Campbell ID. PMID: 19843520.
      View in: PubMed   Mentions: 59     Fields:    Translation:AnimalsCells
    93. Dependence of proliferative vascular smooth muscle cells on CD98hc (4F2hc, SLC3A2). J Exp Med. 2009 Oct 26; 206(11):2397-406. Fogelstrand P, Féral CC, Zargham R, Ginsberg MH. PMID: 19841087.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    94. Slit2-Robo4 signalling promotes vascular stability by blocking Arf6 activity. Nat Cell Biol. 2009 Nov; 11(11):1325-31. Jones CA, Nishiya N, London NR, Zhu W, Sorensen LK, Chan AC, Lim CJ, Chen H, Zhang Q, Schultz PG, Hayallah AM, Thomas KR, Famulok M, Zhang K, Ginsberg MH, Li DY. PMID: 19855388.
      View in: PubMed   Mentions: 99     Fields:    Translation:HumansAnimalsCells
    95. The structure of an integrin/talin complex reveals the basis of inside-out signal transduction. EMBO J. 2009 Nov 18; 28(22):3623-32. Anthis NJ, Wegener KL, Ye F, Kim C, Goult BT, Lowe ED, Vakonakis I, Bate N, Critchley DR, Ginsberg MH, Campbell ID. PMID: 19798053.
      View in: PubMed   Mentions: 150     Fields:    Translation:AnimalsCells
    96. Talin phosphorylation by Cdk5 regulates Smurf1-mediated talin head ubiquitylation and cell migration. Nat Cell Biol. 2009 May; 11(5):624-30. Huang C, Rajfur Z, Yousefi N, Chen Z, Jacobson K, Ginsberg MH. PMID: 19363486.
      View in: PubMed   Mentions: 102     Fields:    Translation:HumansAnimalsCells
    97. The structure of the integrin alphaIIbbeta3 transmembrane complex explains integrin transmembrane signalling. EMBO J. 2009 May 06; 28(9):1351-61. Lau TL, Kim C, Ginsberg MH, Ulmer TS. PMID: 19279667.
      View in: PubMed   Mentions: 148     Fields:    Translation:HumansCells
    98. CD98hc facilitates B cell proliferation and adaptive humoral immunity. Nat Immunol. 2009 Apr; 10(4):412-9. Cantor J, Browne CD, Ruppert R, Féral CC, Fässler R, Rickert RC, Ginsberg MH. PMID: 19270713.
      View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
    99. Interactions of platelet integrin alphaIIb and beta3 transmembrane domains in mammalian cell membranes and their role in integrin activation. Blood. 2009 May 07; 113(19):4747-53. Kim C, Lau TL, Ulmer TS, Ginsberg MH. PMID: 19218549.
      View in: PubMed   Mentions: 46     Fields:    Translation:AnimalsCells
    100. An easy to assemble microfluidic perfusion device with a magnetic clamp. Lab Chip. 2009 Apr 21; 9(8):1085-95. Tkachenko E, Gutierrez E, Ginsberg MH, Groisman A. PMID: 19350090.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCells
    101. Structural determinants of integrin binding to the talin rod. J Biol Chem. 2009 Mar 27; 284(13):8866-76. Gingras AR, Ziegler WH, Bobkov AA, Joyce MG, Fasci D, Himmel M, Rothemund S, Ritter A, Grossmann JG, Patel B, Bate N, Goult BT, Emsley J, Barsukov IL, Roberts GC, Liddington RC, Ginsberg MH, Critchley DR. PMID: 19176533.
      View in: PubMed   Mentions: 42     Fields:    Translation:AnimalsCells
    102. Regulation of cardiovascular development and integrity by the heart of glass-cerebral cavernous malformation protein pathway. Nat Med. 2009 Feb; 15(2):169-76. Kleaveland B, Zheng X, Liu JJ, Blum Y, Tung JJ, Zou Z, Sweeney SM, Chen M, Guo L, Lu MM, Zhou D, Kitajewski J, Affolter M, Ginsberg MH, Kahn ML. PMID: 19151727.
      View in: PubMed   Mentions: 96     Fields:    Translation:HumansAnimalsCells
    103. RIAM activates integrins by linking talin to ras GTPase membrane-targeting sequences. J Biol Chem. 2009 Feb 20; 284(8):5119-27. Lee HS, Lim CJ, Puzon-McLaughlin W, Shattil SJ, Ginsberg MH. PMID: 19098287.
      View in: PubMed   Mentions: 143     Fields:    Translation:HumansAnimalsCells
    104. Antithrombotic effects of targeting alphaIIbbeta3 signaling in platelets. Blood. 2009 Apr 09; 113(15):3585-92. Ablooglu AJ, Kang J, Petrich BG, Ginsberg MH, Shattil SJ. PMID: 19005179.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    105. UV-C irradiation disrupts platelet surface disulfide bonds and activates the platelet integrin alphaIIbbeta3. Blood. 2008 Dec 15; 112(13):4935-9. Verhaar R, Dekkers DW, De Cuyper IM, Ginsberg MH, de Korte D, Verhoeven AJ. PMID: 18796633.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    106. Integrin-mediated protein kinase A activation at the leading edge of migrating cells. Mol Biol Cell. 2008 Nov; 19(11):4930-41. Lim CJ, Kain KH, Tkachenko E, Goldfinger LE, Gutierrez E, Allen MD, Groisman A, Zhang J, Ginsberg MH. PMID: 18784251.
      View in: PubMed   Mentions: 48     Fields:    Translation:AnimalsCells
    107. Cell-to-cell contact and extracellular matrix. Curr Opin Cell Biol. 2008 Oct; 20(5):492-4. Ginsberg MH, Schwarzbauer JE. PMID: 18656543.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    108. Microfluidic devices for studies of shear-dependent platelet adhesion. Lab Chip. 2008 Sep; 8(9):1486-95. Gutierrez E, Petrich BG, Shattil SJ, Ginsberg MH, Groisman A, Kasirer-Friede A. PMID: 18818803.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansAnimalsCells
    109. Localized alpha4 integrin phosphorylation directs shear stress-induced endothelial cell alignment. Circ Res. 2008 Jul 18; 103(2):177-85. Goldfinger LE, Tzima E, Stockton R, Kiosses WB, Kinbara K, Tkachenko E, Gutierrez E, Groisman A, Nguyen P, Chien S, Ginsberg MH. PMID: 18583710.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    110. Mechanisms and consequences of agonist-induced talin recruitment to platelet integrin alphaIIbbeta3. J Cell Biol. 2008 Jun 30; 181(7):1211-22. Watanabe N, Bodin L, Pandey M, Krause M, Coughlin S, Boussiotis VA, Ginsberg MH, Shattil SJ. PMID: 18573917.
      View in: PubMed   Mentions: 76     Fields:    Translation:HumansAnimalsCells
    111. Integrin-associated proteins as potential therapeutic targets. Immunol Rev. 2008 Jun; 223:236-51. Cantor JM, Ginsberg MH, Rose DM. PMID: 18613840.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimalsCells
    112. Differences in regulation of Drosophila and vertebrate integrin affinity by talin. Mol Biol Cell. 2008 Aug; 19(8):3589-98. Helsten TL, Bunch TA, Kato H, Yamanouchi J, Choi SH, Jannuzi AL, Féral CC, Ginsberg MH, Brower DL, Shattil SJ. PMID: 18508915.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    113. Blockade of alpha4 integrin signaling ameliorates the metabolic consequences of high-fat diet-induced obesity. Diabetes. 2008 Jul; 57(7):1842-51. Féral CC, Neels JG, Kummer C, Slepak M, Olefsky JM, Ginsberg MH. PMID: 18426864.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    114. Integrin activation. Biochem Soc Trans. 2008 Apr; 36(Pt 2):229-34. Banno A, Ginsberg MH. PMID: 18363565.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansCells
    115. Robo4 stabilizes the vascular network by inhibiting pathologic angiogenesis and endothelial hyperpermeability. Nat Med. 2008 Apr; 14(4):448-53. Jones CA, London NR, Chen H, Park KW, Sauvaget D, Stockton RA, Wythe JD, Suh W, Larrieu-Lahargue F, Mukouyama YS, Lindblom P, Seth P, Frias A, Nishiya N, Ginsberg MH, Gerhardt H, Zhang K, Li DY. PMID: 18345009.
      View in: PubMed   Mentions: 166     Fields:    Translation:HumansAnimalsCells
    116. Structure of the integrin beta3 transmembrane segment in phospholipid bicelles and detergent micelles. Biochemistry. 2008 Apr 01; 47(13):4008-16. Lau TL, Partridge AW, Ginsberg MH, Ulmer TS. PMID: 18321071.
      View in: PubMed   Mentions: 61     Fields:    Translation:HumansCells
    117. A small molecule inhibitor of alpha4 integrin-dependent cell migration. Bioorg Med Chem. 2009 Feb 01; 17(3):977-80. Lee J, Hong J, Nam TG, Peters EC, Orth AP, Geierstanger BH, Goldfinger LE, Ginsberg MH, Cho CY, Schultz PG. PMID: 18329275.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    118. Talin is required for integrin-mediated platelet function in hemostasis and thrombosis. J Exp Med. 2007 Dec 24; 204(13):3103-11. Petrich BG, Marchese P, Ruggeri ZM, Spiess S, Weichert RA, Ye F, Tiedt R, Skoda RC, Monkley SJ, Critchley DR, Ginsberg MH. PMID: 18086863.
      View in: PubMed   Mentions: 121     Fields:    Translation:AnimalsCells
    119. KRIT-1/CCM1 is a Rap1 effector that regulates endothelial cell cell junctions. J Cell Biol. 2007 Oct 22; 179(2):247-54. Glading A, Han J, Stockton RA, Ginsberg MH. PMID: 17954608.
      View in: PubMed   Mentions: 149     Fields:    Translation:HumansAnimalsCells
    120. CD98hc (SLC3A2) participates in fibronectin matrix assembly by mediating integrin signaling. J Cell Biol. 2007 Aug 13; 178(4):701-11. Féral CC, Zijlstra A, Tkachenko E, Prager G, Gardel ML, Slepak M, Ginsberg MH. PMID: 17682053.
      View in: PubMed   Mentions: 41     Fields:    Translation:AnimalsCells
    121. Integrin modulation and signaling in leukocyte adhesion and migration. Immunol Rev. 2007 Aug; 218:126-34. Rose DM, Alon R, Ginsberg MH. PMID: 17624949.
      View in: PubMed   Mentions: 93     Fields:    Translation:HumansAnimalsCells
    122. The antithrombotic potential of selective blockade of talin-dependent integrin alpha IIb beta 3 (platelet GPIIb-IIIa) activation. J Clin Invest. 2007 Aug; 117(8):2250-9. Petrich BG, Fogelstrand P, Partridge AW, Yousefi N, Ablooglu AJ, Shattil SJ, Ginsberg MH. PMID: 17627302.
      View in: PubMed   Mentions: 65     Fields:    Translation:AnimalsCells
    123. Neurite outgrowth on a fibronectin isoform expressed during peripheral nerve regeneration is mediated by the interaction of paxillin with alpha4beta1 integrins. BMC Neurosci. 2007 Jun 29; 8:44. Vogelezang M, Forster UB, Han J, Ginsberg MH, ffrench-Constant C. PMID: 17603879.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    124. CD98hc (SLC3A2) interaction with the integrin beta subunit cytoplasmic domain mediates adhesive signaling. J Biol Chem. 2007 Aug 17; 282(33):24477-84. Prager GW, Féral CC, Kim C, Han J, Ginsberg MH. PMID: 17597067.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimalsCells
    125. Small-molecule synergist of the Wnt/beta-catenin signaling pathway. Proc Natl Acad Sci U S A. 2007 May 01; 104(18):7444-8. Zhang Q, Major MB, Takanashi S, Camp ND, Nishiya N, Peters EC, Ginsberg MH, Jian X, Randazzo PA, Schultz PG, Moon RT, Ding S. PMID: 17460038.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansAnimalsCells
    126. An experimentally derived database of candidate Ras-interacting proteins. J Proteome Res. 2007 May; 6(5):1806-11. Goldfinger LE, Ptak C, Jeffery ED, Shabanowitz J, Han J, Haling JR, Sherman NE, Fox JW, Hunt DF, Ginsberg MH. PMID: 17439166.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    127. Alpha4 integrins are type I cAMP-dependent protein kinase-anchoring proteins. Nat Cell Biol. 2007 Apr; 9(4):415-21. Lim CJ, Han J, Yousefi N, Ma Y, Amieux PS, McKnight GS, Taylor SS, Ginsberg MH. PMID: 17369818.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansAnimalsCells
    128. Syk, c-Src, the alphavbeta3 integrin, and ITAM immunoreceptors, in concert, regulate osteoclastic bone resorption. J Cell Biol. 2007 Mar 12; 176(6):877-88. Zou W, Kitaura H, Reeve J, Long F, Tybulewicz VL, Shattil SJ, Ginsberg MH, Ross FP, Teitelbaum SL. PMID: 17353363.
      View in: PubMed   Mentions: 116     Fields:    Translation:HumansAnimalsCells
    129. PEA-15 inhibits tumor cell invasion by binding to extracellular signal-regulated kinase 1/2. Cancer Res. 2007 Feb 15; 67(4):1536-44. Glading A, Koziol JA, Krueger J, Ginsberg MH. PMID: 17308092.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    130. Structural basis of integrin activation by talin. Cell. 2007 Jan 12; 128(1):171-82. Wegener KL, Partridge AW, Han J, Pickford AR, Liddington RC, Ginsberg MH, Campbell ID. PMID: 17218263.
      View in: PubMed   Mentions: 285     Fields:    Translation:AnimalsCells
    131. Reconstructing and deconstructing agonist-induced activation of integrin alphaIIbbeta3. Curr Biol. 2006 Sep 19; 16(18):1796-806. Han J, Lim CJ, Watanabe N, Soriani A, Ratnikov B, Calderwood DA, Puzon-McLaughlin W, Lafuente EM, Boussiotis VA, Shattil SJ, Ginsberg MH. PMID: 16979556.
      View in: PubMed   Mentions: 196     Fields:    Translation:HumansAnimalsCells
    132. RLIP76 (RalBP1) is an R-Ras effector that mediates adhesion-dependent Rac activation and cell migration. J Cell Biol. 2006 Sep 11; 174(6):877-88. Goldfinger LE, Ptak C, Jeffery ED, Shabanowitz J, Hunt DF, Ginsberg MH. PMID: 16966426.
      View in: PubMed   Mentions: 39     Fields:    Translation:AnimalsCells
    133. Matrix-specific suppression of integrin activation in shear stress signaling. Mol Biol Cell. 2006 Nov; 17(11):4686-97. Orr AW, Ginsberg MH, Shattil SJ, Deckmyn H, Schwartz MA. PMID: 16928957.
      View in: PubMed   Mentions: 70     Fields:    Translation:AnimalsCells
    134. Phospholipase C epsilon suppresses integrin activation. J Biol Chem. 2006 Oct 06; 281(40):29501-12. Lad Y, McHugh B, Hodkinson PS, Mackinnon AC, Haslett C, Ginsberg MH, Sethi T. PMID: 16895916.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    135. New approaches to blockade of alpha4-integrins, proven therapeutic targets in chronic inflammation. Biochem Pharmacol. 2006 Nov 30; 72(11):1460-8. Kummer C, Ginsberg MH. PMID: 16870156.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    136. Blocking the alpha 4 integrin-paxillin interaction selectively impairs mononuclear leukocyte recruitment to an inflammatory site. J Clin Invest. 2006 Mar; 116(3):715-23. Féral CC, Rose DM, Han J, Fox N, Silverman GJ, Kaushansky K, Ginsberg MH. PMID: 16470243.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    137. Alpha4beta1-dependent adhesion strengthening under mechanical strain is regulated by paxillin association with the alpha4-cytoplasmic domain. J Cell Biol. 2005 Dec 19; 171(6):1073-84. Alon R, Feigelson SW, Manevich E, Rose DM, Schmitz J, Overby DR, Winter E, Grabovsky V, Shinder V, Matthews BD, Sokolovsky-Eisenberg M, Ingber DE, Benoit M, Ginsberg MH. PMID: 16365170.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansCells
    138. Integrin alpha4beta1 promotes focal adhesion kinase-independent cell motility via alpha4 cytoplasmic domain-specific activation of c-Src. Mol Cell Biol. 2005 Nov; 25(21):9700-12. Hsia DA, Lim ST, Bernard-Trifilo JA, Mitra SK, Tanaka S, den Hertog J, Streblow DN, Ilic D, Ginsberg MH, Schlaepfer DD. PMID: 16227616.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansAnimalsCells
    139. Talin phosphorylation sites mapped by mass spectrometry. J Cell Sci. 2005 Nov 01; 118(Pt 21):4921-3. Ratnikov B, Ptak C, Han J, Shabanowitz J, Hunt DF, Ginsberg MH. PMID: 16254238.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    140. Integrin regulation. Curr Opin Cell Biol. 2005 Oct; 17(5):509-16. Ginsberg MH, Partridge A, Shattil SJ. PMID: 16099636.
      View in: PubMed   Mentions: 188     Fields:    Translation:HumansCells
    141. Specification of the direction of adhesive signaling by the integrin beta cytoplasmic domain. J Biol Chem. 2005 Aug 19; 280(33):29699-707. Arias-Salgado EG, Lizano S, Shattil SJ, Ginsberg MH. PMID: 15937333.
      View in: PubMed   Mentions: 44     Fields:    Translation:Cells
    142. Phosphorylation of phosphoprotein enriched in astrocytes (PEA-15) regulates extracellular signal-regulated kinase-dependent transcription and cell proliferation. Mol Biol Cell. 2005 Aug; 16(8):3552-61. Krueger J, Chou FL, Glading A, Schaefer E, Ginsberg MH. PMID: 15917297.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimalsCells
    143. An alpha4 integrin-paxillin-Arf-GAP complex restricts Rac activation to the leading edge of migrating cells. Nat Cell Biol. 2005 Apr; 7(4):343-52. Nishiya N, Kiosses WB, Han J, Ginsberg MH. PMID: 15793570.
      View in: PubMed   Mentions: 102     Fields:    Translation:AnimalsCells
    144. CD98hc (SLC3A2) mediates integrin signaling. Proc Natl Acad Sci U S A. 2005 Jan 11; 102(2):355-60. Feral CC, Nishiya N, Fenczik CA, Stuhlmann H, Slepak M, Ginsberg MH. PMID: 15625115.
      View in: PubMed   Mentions: 97     Fields:    Translation:AnimalsCells
    145. Structural basis for phosphatidylinositol phosphate kinase type Igamma binding to talin at focal adhesions. J Biol Chem. 2005 Mar 04; 280(9):8381-6. de Pereda JM, Wegener KL, Santelli E, Bate N, Ginsberg MH, Critchley DR, Campbell ID, Liddington RC. PMID: 15623515.
      View in: PubMed   Mentions: 39     Fields:    Translation:AnimalsCells
    146. Transmembrane domain helix packing stabilizes integrin alphaIIbbeta3 in the low affinity state. J Biol Chem. 2005 Feb 25; 280(8):7294-300. Partridge AW, Liu S, Kim S, Bowie JU, Ginsberg MH. PMID: 15591321.
      View in: PubMed   Mentions: 62     Fields:    Translation:AnimalsCells
    147. CD98hc (SLC3A2) interaction with beta 1 integrins is required for transformation. J Biol Chem. 2004 Dec 24; 279(52):54731-41. Henderson NC, Collis EA, Mackinnon AC, Simpson KJ, Haslett C, Zent R, Ginsberg M, Sethi T. PMID: 15485886.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimalsCells
    148. The talin-tail interaction places integrin activation on FERM ground. Trends Biochem Sci. 2004 Aug; 29(8):429-35. Campbell ID, Ginsberg MH. PMID: 15362227.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansAnimalsCells
    149. Competition for talin results in trans-dominant inhibition of integrin activation. J Biol Chem. 2004 Jul 09; 279(28):28889-95. Calderwood DA, Tai V, Di Paolo G, De Camilli P, Ginsberg MH. PMID: 15143061.
      View in: PubMed   Mentions: 45     Fields:    Translation:AnimalsCells
    150. Neurobiology: New connections between integrins and axon guidance. Curr Biol. 2004 Feb 03; 14(3):R121-3. Nakamoto T, Kain KH, Ginsberg MH. PMID: 14986683.
      View in: PubMed   Mentions: 19     Fields:    Translation:Cells
    151. Cell migration: integrating signals from front to back. Science. 2003 Dec 05; 302(5651):1704-9. Ridley AJ, Schwartz MA, Burridge K, Firtel RA, Ginsberg MH, Borisy G, Parsons JT, Horwitz AR. PMID: 14657486.
      View in: PubMed   Mentions: 1765     Fields:    Translation:HumansAnimalsCells
    152. C-terminal sequences in R-Ras are involved in integrin regulation and in plasma membrane microdomain distribution. Biochem Biophys Res Commun. 2003 Nov 28; 311(4):829-38. Hansen M, Prior IA, Hughes PE, Oertli B, Chou FL, Willumsen BM, Hancock JF, Ginsberg MH. PMID: 14623256.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    153. The Kindler syndrome protein is regulated by transforming growth factor-beta and involved in integrin-mediated adhesion. J Biol Chem. 2004 Feb 20; 279(8):6824-33. Kloeker S, Major MB, Calderwood DA, Ginsberg MH, Jones DA, Beckerle MC. PMID: 14634021.
      View in: PubMed   Mentions: 61     Fields:    Translation:HumansCells
    154. Src kinase activation by direct interaction with the integrin beta cytoplasmic domain. Proc Natl Acad Sci U S A. 2003 Nov 11; 100(23):13298-302. Arias-Salgado EG, Lizano S, Sarkar S, Brugge JS, Ginsberg MH, Shattil SJ. PMID: 14593208.
      View in: PubMed   Mentions: 219     Fields:    Translation:AnimalsCells
    155. Talin binding to integrin beta tails: a final common step in integrin activation. Science. 2003 Oct 03; 302(5642):103-6. Tadokoro S, Shattil SJ, Eto K, Tai V, Liddington RC, de Pereda JM, Ginsberg MH, Calderwood DA. PMID: 14526080.
      View in: PubMed   Mentions: 441     Fields:    Translation:HumansAnimalsCells
    156. Ras GTPases: integrins' friends or foes? Nat Rev Mol Cell Biol. 2003 Oct; 4(10):767-76. Kinbara K, Goldfinger LE, Hansen M, Chou FL, Ginsberg MH. PMID: 14570053.
      View in: PubMed   Mentions: 76     Fields:    Translation:HumansAnimalsCells
    157. PEA-15 binding to ERK1/2 MAPKs is required for its modulation of integrin activation. J Biol Chem. 2003 Dec 26; 278(52):52587-97. Chou FL, Hill JM, Hsieh JC, Pouyssegur J, Brunet A, Glading A, Uberall F, Ramos JW, Werner MH, Ginsberg MH. PMID: 14506247.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    158. Spatial restriction of alpha4 integrin phosphorylation regulates lamellipodial stability and alpha4beta1-dependent cell migration. J Cell Biol. 2003 Aug 18; 162(4):731-41. Goldfinger LE, Han J, Kiosses WB, Howe AK, Ginsberg MH. PMID: 12913113.
      View in: PubMed   Mentions: 50     Fields:    Translation:AnimalsCells
    159. Talin forges the links between integrins and actin. Nat Cell Biol. 2003 Aug; 5(8):694-7. Calderwood DA, Ginsberg MH. PMID: 12894175.
      View in: PubMed   Mentions: 54     Fields:    Translation:AnimalsCells
    160. Domain-specific interactions of talin with the membrane-proximal region of the integrin beta3 subunit. Biochemistry. 2003 Jul 15; 42(27):8307-12. Ulmer TS, Calderwood DA, Ginsberg MH, Campbell ID. PMID: 12846579.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    161. Integrin alpha 4 beta 1-dependent T cell migration requires both phosphorylation and dephosphorylation of the alpha 4 cytoplasmic domain to regulate the reversible binding of paxillin. J Biol Chem. 2003 Sep 12; 278(37):34845-53. Han J, Rose DM, Woodside DG, Goldfinger LE, Ginsberg MH. PMID: 12837751.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    162. Paxillin binding to the alpha 4 integrin subunit stimulates LFA-1 (integrin alpha L beta 2)-dependent T cell migration by augmenting the activation of focal adhesion kinase/proline-rich tyrosine kinase-2. J Immunol. 2003 Jun 15; 170(12):5912-8. Rose DM, Liu S, Woodside DG, Han J, Schlaepfer DD, Ginsberg MH. PMID: 12794117.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansCells
    163. Integrin beta cytoplasmic domain interactions with phosphotyrosine-binding domains: a structural prototype for diversity in integrin signaling. Proc Natl Acad Sci U S A. 2003 Mar 04; 100(5):2272-7. Calderwood DA, Fujioka Y, de Pereda JM, García-Alvarez B, Nakamoto T, Margolis B, McGlade CJ, Liddington RC, Ginsberg MH. PMID: 12606711.
      View in: PubMed   Mentions: 127     Fields:    Translation:HumansAnimalsCells
    164. Structural determinants of integrin recognition by talin. Mol Cell. 2003 Jan; 11(1):49-58. García-Alvarez B, de Pereda JM, Calderwood DA, Ulmer TS, Critchley D, Campbell ID, Ginsberg MH, Liddington RC. PMID: 12535520.
      View in: PubMed   Mentions: 196     Fields:    Translation:AnimalsCells
    165. Recognition of ERK MAP kinase by PEA-15 reveals a common docking site within the death domain and death effector domain. EMBO J. 2002 Dec 02; 21(23):6494-504. Hill JM, Vaidyanathan H, Ramos JW, Ginsberg MH, Werner MH. PMID: 12456656.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
    166. Blockade of platelet GPIIB-IIIA (Integrin alphaII(b)beta(3)) in flowing human blood leads to passivation of prothrombotic surfaces. Thromb Haemost. 2002 Nov; 88(5):858-64. Riederer MA, Ginsberg MH, Steiner B. PMID: 12428106.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    167. Inhibitors of cell migration that inhibit intracellular paxillin/alpha4 binding: a well-documented use of positional scanning libraries. Chem Biol. 2002 Nov; 9(11):1219-26. Ambroise Y, Yaspan B, Ginsberg MH, Boger DL. PMID: 12445772.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    168. Genetic interaction between integrins and moleskin, a gene encoding a Drosophila homolog of importin-7. Genetics. 2002 Sep; 162(1):285-96. Baker SE, Lorenzen JA, Miller SW, Bunch TA, Jannuzi AL, Ginsberg MH, Perkins LA, Brower DL. PMID: 12242240.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    169. The N-terminal SH2 domains of Syk and ZAP-70 mediate phosphotyrosine-independent binding to integrin beta cytoplasmic domains. J Biol Chem. 2002 Oct 18; 277(42):39401-8. Woodside DG, Obergfell A, Talapatra A, Calderwood DA, Shattil SJ, Ginsberg MH. PMID: 12171941.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    170. Alpha4 integrins and the immune response. Immunol Rev. 2002 Aug; 186:118-24. Rose DM, Han J, Ginsberg MH. PMID: 12234367.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansAnimalsCells
    171. Suppression of integrin activation by activated Ras or Raf does not correlate with bulk activation of ERK MAP kinase. Mol Biol Cell. 2002 Jul; 13(7):2256-65. Hughes PE, Oertli B, Hansen M, Chou FL, Willumsen BM, Ginsberg MH. PMID: 12134066.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    172. R-Ras C-terminal sequences are sufficient to confer R-Ras specificity to H-Ras. Oncogene. 2002 Jun 27; 21(28):4448-61. Hansen M, Rusyn EV, Hughes PE, Ginsberg MH, Cox AD, Willumsen BM. PMID: 12080475.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    173. Physical mapping of genes in somatic cell radiation hybrids by comparative genomic hybridization to cDNA microarrays. Genome Biol. 2002; 3(6):RESEARCH0026. Lin JY, Pollack JR, Chou FL, Rees CA, Christian AT, Bedford JS, Brown PO, Ginsberg MH. PMID: 12093373.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    174. The phosphotyrosine binding-like domain of talin activates integrins. J Biol Chem. 2002 Jun 14; 277(24):21749-58. Calderwood DA, Yan B, de Pereda JM, Alvarez BG, Fujioka Y, Liddington RC, Ginsberg MH. PMID: 11932255.
      View in: PubMed   Mentions: 131     Fields:    Translation:AnimalsCells
    175. Networks and crosstalk: integrin signalling spreads. Nat Cell Biol. 2002 Apr; 4(4):E65-8. Schwartz MA, Ginsberg MH. PMID: 11944032.
      View in: PubMed   Mentions: 240     Fields:    Translation:HumansAnimalsCells
    176. A fragment of paxillin binds the alpha 4 integrin cytoplasmic domain (tail) and selectively inhibits alpha 4-mediated cell migration. J Biol Chem. 2002 Jun 07; 277(23):20887-94. Liu S, Kiosses WB, Rose DM, Slepak M, Salgia R, Griffin JD, Turner CE, Schwartz MA, Ginsberg MH. PMID: 11919182.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    177. Expression cloning strategies for the identification of adhesion molecules. Methods Cell Biol. 2002; 69:209-21. Ramos JW, Ginsberg M. PMID: 12070994.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells