Mark Ginsberg

Title(s)Professor, Medicine
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Collapse Overview 
    Collapse Overview
    Dr. Mark H. Ginsberg is a professor of medicine and director of the Physician-Scientist Training Pathway at UC San Diego. Dr. Ginsberg moved his research laboratory from the Scripps Research Institute to the Department of Medicine at the University of California, San Diego in July 2004.

    Research Interests
    Molecular structure and function of integrins in immune responses.

    Education and Training
    Psychology - McGill University, Montreal, Canada - 1965
    MD (Summa cum laude) - State University of NY - 1970
    Intern/Resident - University of Chicago - 1970-1973
    Rheumatology Fellow - University of Chicago - 1973-1975

    Collapse Research 
    Collapse Research Activities and Funding
    Cellular Mechanisms of Inflammation, Hemostasis, and Thrombosis
    NIH P01HL151433Aug 5, 2020 - Jul 31, 2025
    Role: Principal Investigator
    Deconvoluting the Vascular Adhesome
    NIH R35HL139947Jan 1, 2018 - Dec 31, 2024
    Role: Principal Investigator
    Signaling Aberrations and Cerebral Cavernous Malformation Pathogenesis
    NIH P01NS092521Sep 1, 2015 - Jun 30, 2020
    Role: Co-Investigator
    Tilting the Balance of Integrin Activation
    NIH/NHLBI R01HL126844Apr 2, 2015 - Mar 31, 2019
    Role: Principal Investigator
    Composition and Functions of the Integrin Activation Complex
    NIH R01HL117807May 1, 2014 - Apr 30, 2018
    Role: Principal Investigator
    KRIT1 and Vascular Integrity
    NIH R01HL106489Jan 3, 2011 - Dec 31, 2017
    Role: Principal Investigator
    Assembly, dynamics and evolution of cell-cell and cell-matrix adhesions
    NIH U01GM094663Sep 30, 2010 - Jun 30, 2015
    Role: Co-Investigator
    Assay Development for HT Molecular Screening for Inhibitors of Integrin Signaling
    NIH R21NS059433Sep 30, 2007 - Aug 31, 2008
    Role: Principal Investigator
    alpha4beta1 Intergrin Signaling In Immunity And Arthritis
    NIH R01AR052367Jul 1, 2007 - May 31, 2012
    Role: Principal Investigator
    Blood Cells in Hemostasis and Thrombosis
    NIH T32HL086344Jan 1, 2007 - May 30, 2024
    Role: Principal Investigator
    Regulation of Fibronectin Matrix Assembly
    NIH R01HL080529Apr 1, 2005 - Aug 31, 2005
    Role: Principal Investigator
    Cell Adhesion Mechanisms in Vascular Disease & Thrombosis
    NIH P01HL078784Dec 1, 2004 - Apr 30, 2021
    Role: Principal Investigator
    A Proteomics Research Resource for Integrative Biology
    NIH P41RR018522Sep 15, 2003 - Jun 30, 2013
    Role: Co-Investigator
    Cytoplasmic Regulation of a4b1 Avidity under Flow
    NIH R03TW006425Jul 1, 2003 - Jun 30, 2007
    Role: Principal Investigator
    Cell Migration Consortium
    NIH U54GM064346Sep 15, 2001 - Jul 31, 2014
    Role: Co-Investigator
    Integrin Signaling in Hemostasis and Blood Diseases
    NIH P01HL057900Apr 1, 1997 - Jan 31, 2014
    Role: Co-Investigator
    GORDON CONFERENCE--FIBRONECTIN AND MACROMOLECULES
    NIH R13HL049091Feb 1, 1993 - Jan 31, 1994
    Role: Principal Investigator
    CELL ADHESION MECHANISMS IN VASCULAR DISEASE
    NIH P01HL048728Sep 30, 1992 - Aug 31, 2004
    Role: Principal Investigator
    VASCULAR BIOLOGY, THROMBOSIS, AND HEMOSTASIS
    NIH T32HL007695Jul 1, 1991 - Jun 30, 2007
    Role: Principal Investigator
    Thrombus Formation and Antithrombotic Intervention
    NIH P01HL031950Apr 1, 1984 - Jun 30, 2017
    Role: Co-Investigator
    FIBRONECTIN AND PLATELETS
    NIH R01HL028235Jan 1, 1982 - Jun 30, 1996
    Role: Principal Investigator
    Regulation of Integrin Alpha4 Betal
    NIH R01AR027214Aug 1, 1980 - Nov 30, 2011
    Role: Principal Investigator
    PLATELETS IN RHEUMATIC DISEASE
    NIH R37AR027214Aug 1, 1980 - Jan 31, 2001
    Role: Principal Investigator
    GENERAL CLINICAL RESEARCH CENTER
    NIH M01RR000833Dec 1, 1977 - Sep 30, 2005
    Role: Co-Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Mild Hypoxia Accelerates Cerebral Cavernous Malformation Disease Through CX3CR1-CX3CL1 Signaling. Arterioscler Thromb Vasc Biol. 2024 06; 44(6):1246-1264. Frias-Anaya E, Gallego-Gutierrez H, Gongol B, Weinsheimer S, Lai CC, Orecchioni M, Sriram A, Bui CM, Nelsen B, Hale P, Pham A, Shenkar R, DeBiasse D, Lightle R, Girard R, Li Y, Srinath A, Daneman R, Nudleman E, Sun H, Guma M, Dubrac A, Mesarwi OA, Ley K, Kim H, Awad IA, Ginsberg MH, Lopez-Ramirez MA. PMID: 38660801; PMCID: PMC11111348.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    2. Onco-Circuit Addiction and Onco-Nutrient mTORC1 Signaling Vulnerability in a Model of Aggressive T Cell Malignancy. bioRxiv. 2024 Apr 04. Wang X, Cornish AE, Do MH, Brunner JS, Hsu TW, Xu Z, Malik I, Edwards C, Capistrano KJ, Zhang X, Ginsberg MH, Finley LWS, Lim MS, Horwitz SM, Li MO. PMID: 38617314; PMCID: PMC11014592.
      View in: PubMed   Mentions:
    3. Transcriptomic signatures of individual cell types in cerebral cavernous malformation. Cell Commun Signal. 2024 01 09; 22(1):23. Li Y, Girard R, Srinath A, Cruz DV, Ciszewski C, Chen C, Lightle R, Romanos S, Sone JY, Moore T, DeBiasse D, Stadnik A, Lee JJ, Shenkar R, Koskimäki J, Lopez-Ramirez MA, Marchuk DA, Ginsberg MH, Kahn ML, Shi C, Awad IA. PMID: 38195510; PMCID: PMC10775676.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    4. Targeted Reversible Covalent Modification of a Noncatalytic Lysine of the Krev Interaction Trapped 1 Protein Enables Site-Directed Screening for Protein-Protein Interaction Inhibitors. ACS Pharmacol Transl Sci. 2023 Nov 10; 6(11):1651-1658. Francisco KR, Bruystens J, Varricchio C, McCurdy S, Wu J, Lopez-Ramirez MA, Ginsberg M, Caffrey CR, Brancale A, Gingras AR, Hixon MS, Ballatore C. PMID: 37974623; PMCID: PMC10644391.
      View in: PubMed   Mentions: 1  
    5. IL-2 can signal via chemokine receptors to promote regulatory T cells' suppressive function. Cell Rep. 2023 08 29; 42(8):112996. Sun H, Lee HS, Kim SH, Fernandes de Lima M, Gingras AR, Du Q, McLaughlin W, Ablack J, Lopez-Ramirez MA, Lagarrigue F, Fan Z, Chang JT, VanDyke D, Spangler JB, Ginsberg MH. PMID: 37598341; PMCID: PMC10564087.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    6. Protease-activated receptors and glycoprotein VI cooperatively drive the platelet component in thromboelastography. J Thromb Haemost. 2023 08; 21(8):2236-2247. Rudran T, Antoniak S, Flick MJ, Ginsberg MH, Wolberg AS, Bergmeier W, Lee RH. PMID: 37068592; PMCID: PMC10824270.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    7. β1 integrin monoclonal antibody treatment ameliorates cerebral cavernous malformations. FASEB J. 2022 12; 36(12):e22629. McCurdy S, Lin J, Shenkar R, Moore T, Lightle R, Faurobert E, Lopez-Ramirez MA, Awad I, Ginsberg MH. PMID: 36349990; PMCID: PMC9674378.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    8. Phostensin enables lymphocyte integrin activation and population of peripheral lymphoid organs. J Exp Med. 2022 08 01; 219(8). Lee HS, Sun H, Lagarrigue F, Kim SHJ, Fox JW, Sherman NE, Gingras AR, Ginsberg MH. PMID: 35766979; PMCID: PMC9247717.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    9. Circulating Plasma miRNA Homologs in Mice and Humans Reflect Familial Cerebral Cavernous Malformation Disease. Transl Stroke Res. 2023 08; 14(4):513-529. Romanos SG, Srinath A, Li Y, Xie B, Chen C, Li Y, Moore T, Bi D, Sone JY, Lightle R, Hobson N, Zhang D, Koskimäki J, Shen L, McCurdy S, Lai CC, Stadnik A, Piedad K, Carrión-Penagos J, Shkoukani A, Snellings D, Shenkar R, Sulakhe D, Ji Y, Lopez-Ramirez MA, Kahn ML, Marchuk DA, Ginsberg MH, Girard R, Awad IA. PMID: 35715588; PMCID: PMC9758276.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    10. The Connection Between Rap1 and Talin1 in the Activation of Integrins in Blood Cells. Front Cell Dev Biol. 2022; 10:908622. Sun H, Lagarrigue F, Ginsberg MH. PMID: 35721481; PMCID: PMC9198492.
      View in: PubMed   Mentions: 5  
    11. Propranolol inhibits cavernous vascular malformations by β1 adrenergic receptor antagonism in animal models. J Clin Invest. 2021 10 01; 131(19). Li W, Shenkar R, Detter MR, Moore T, Benavides C, Lightle R, Girard R, Hobson N, Cao Y, Li Y, Griffin E, Gallione C, Zabramski JM, Ginsberg MH, Marchuk DA, Awad IA. PMID: 34596055; PMCID: PMC8483741.
      View in: PubMed   Mentions: 15     Fields:    
    12. Astrocytes propel neurovascular dysfunction during cerebral cavernous malformation lesion formation. J Clin Invest. 2021 07 01; 131(13). Lopez-Ramirez MA, Lai CC, Soliman SI, Hale P, Pham A, Estrada EJ, McCurdy S, Girard R, Verma R, Moore T, Lightle R, Hobson N, Shenkar R, Poulsen O, Haddad GG, Daneman R, Gongol B, Sun H, Lagarrigue F, Awad IA, Ginsberg MH. PMID: 34043589; PMCID: PMC8245174.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
    13. Cerebral Cavernous Malformation: From Mechanism to Therapy. Circ Res. 2021 06 25; 129(1):195-215. Snellings DA, Hong CC, Ren AA, Lopez-Ramirez MA, Girard R, Srinath A, Marchuk DA, Ginsberg MH, Awad IA, Kahn ML. PMID: 34166073; PMCID: PMC8922476.
      View in: PubMed   Mentions: 58     Fields:    Translation:HumansAnimalsCells
    14. Abortive intussusceptive angiogenesis causes multi-cavernous vascular malformations. Elife. 2021 05 20; 10. Li W, Tran V, Shaked I, Xue B, Moore T, Lightle R, Kleinfeld D, Awad IA, Ginsberg MH. PMID: 34013885; PMCID: PMC8175082.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    15. Optogenetics-based localization of talin to the plasma membrane promotes activation of β3 integrins. J Biol Chem. 2021 Jan-Jun; 296:100675. Liao Z, Gingras AR, Lagarrigue F, Ginsberg MH, Shattil SJ. PMID: 33865854; PMCID: PMC8131925.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    16. Endothelial struts enable the generation of large lumenized blood vessels de novo. Nat Cell Biol. 2021 04; 23(4):322-329. Weijts B, Shaked I, Ginsberg M, Kleinfeld D, Robin C, Traver D. PMID: 33837285; PMCID: PMC8500358.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    17. Propranolol inhibits cavernous vascular malformations by β1 adrenergic receptor antagonism in animal models. J Clin Invest. 2021 02 01; 131(3). Li W, Shenkar R, Detter MR, Moore T, Benavides C, Lightle R, Girard R, Hobson N, Cao Y, Li Y, Griffin E, Gallione C, Zabramski JM, Ginsberg MH, Marchuk DA, Awad IA. PMID: 33301422; PMCID: PMC7843213.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    18. Distinct integrin activation pathways for effector and regulatory T cell trafficking and function. J Exp Med. 2021 02 01; 218(2). Sun H, Lagarrigue F, Wang H, Fan Z, Lopez-Ramirez MA, Chang JT, Ginsberg MH. PMID: 33104169; PMCID: PMC7590511.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    19. Kindlin-3 recruitment to the plasma membrane precedes high-affinity β2-integrin and neutrophil arrest from rolling. Blood. 2021 01 07; 137(1):29-38. Wen L, Marki A, Roy P, McArdle S, Sun H, Fan Z, Gingras AR, Ginsberg MH, Ley K. PMID: 32777822; PMCID: PMC7808012.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    20. A stem cell reporter based platform to identify and target drug resistant stem cells in myeloid leukemia. Nat Commun. 2020 11 26; 11(1):5998. Spinler K, Bajaj J, Ito T, Zimdahl B, Hamilton M, Ahmadi A, Koechlein CS, Lytle N, Kwon HY, Anower-E-Khuda F, Sun H, Blevins A, Weeks J, Kritzik M, Karlseder J, Ginsberg MH, Park PW, Esko JD, Reya T. PMID: 33243988; PMCID: PMC7691523.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    21. MARCH Proteins Mediate Responses to Antitumor Antibodies. J Immunol. 2020 11 15; 205(10):2883-2892. Ablack JN, Ortiz J, Bajaj J, Trinh K, Lagarrigue F, Cantor JM, Reya T, Ginsberg MH. PMID: 33077644; PMCID: PMC9382848.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    22. Talin-1 is the principal platelet Rap1 effector of integrin activation. Blood. 2020 09 03; 136(10):1180-1190. Lagarrigue F, Paul DS, Gingras AR, Valadez AJ, Sun H, Lin J, Cuevas MN, Ablack JN, Lopez-Ramirez MA, Bergmeier W, Ginsberg MH. PMID: 32518959; PMCID: PMC7472713.
      View in: PubMed   Mentions: 35     Fields:    Translation:AnimalsCells
    23. Signal Transduction: Physical Deformation of the Membrane Activates Integrins. Curr Biol. 2020 05 04; 30(9):R397-R400. Gingras AR, Ginsberg MH. PMID: 32369751.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    24. β7 Integrin Inhibition Can Increase Intestinal Inflammation by Impairing Homing of CD25hiFoxP3+ Regulatory T Cells. Cell Mol Gastroenterol Hepatol. 2020; 9(3):369-385. Sun H, Kuk W, Rivera-Nieves J, Lopez-Ramirez MA, Eckmann L, Ginsberg MH. PMID: 31707128; PMCID: PMC7016000.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    25. Frontline Science: A flexible kink in the transmembrane domain impairs β2 integrin extension and cell arrest from rolling. J Leukoc Biol. 2020 02; 107(2):175-183. Sun H, Fan Z, Gingras AR, Lopez-Ramirez MA, Ginsberg MH, Ley K. PMID: 31475386; PMCID: PMC6987018.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    26. Transcriptome clarifies mechanisms of lesion genesis versus progression in models of Ccm3 cerebral cavernous malformations. Acta Neuropathol Commun. 2019 08 19; 7(1):132. Koskimäki J, Zhang D, Li Y, Saadat L, Moore T, Lightle R, Polster SP, Carrión-Penagos J, Lyne SB, Zeineddine HA, Shi C, Shenkar R, Romanos S, Avner K, Srinath A, Shen L, Detter MR, Snellings D, Cao Y, Lopez-Ramirez MA, Fonseca G, Tang AT, Faber P, Andrade J, Ginsberg M, Kahn ML, Marchuk DA, Girard R, Awad IA. PMID: 31426861; PMCID: PMC6699077.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    27. Biomarkers of cavernous angioma with symptomatic hemorrhage. JCI Insight. 2019 06 20; 4(12). Lyne SB, Girard R, Koskimäki J, Zeineddine HA, Zhang D, Cao Y, Li Y, Stadnik A, Moore T, Lightle R, Shi C, Shenkar R, Carrión-Penagos J, Polster SP, Romanos S, Akers A, Lopez-Ramirez M, Whitehead KJ, Kahn ML, Ginsberg MH, Marchuk DA, Awad IA. PMID: 31217347; PMCID: PMC6629090.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    28. Rap1 binding and a lipid-dependent helix in talin F1 domain promote integrin activation in tandem. J Cell Biol. 2019 06 03; 218(6):1799-1809. Gingras AR, Lagarrigue F, Cuevas MN, Valadez AJ, Zorovich M, McLaughlin W, Lopez-Ramirez MA, Seban N, Ley K, Kiosses WB, Ginsberg MH. PMID: 30988001; PMCID: PMC6548133.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimalsCells
    29. Comprehensive transcriptome analysis of cerebral cavernous malformation across multiple species and genotypes. JCI Insight. 2019 Feb 07; 4(3). Koskimäki J, Girard R, Li Y, Saadat L, Zeineddine HA, Lightle R, Moore T, Lyne S, Avner K, Shenkar R, Cao Y, Shi C, Polster SP, Zhang D, Carrión-Penagos J, Romanos S, Fonseca G, Lopez-Ramirez MA, Chapman EM, Popiel E, Tang AT, Akers A, Faber P, Andrade J, Ginsberg M, Derry WB, Kahn ML, Marchuk DA, Awad IA. PMID: 30728328; PMCID: PMC6413775.
      View in: PubMed   Mentions: 32     Fields:    
    30. High-Affinity Bent β2-Integrin Molecules in Arresting Neutrophils Face Each Other through Binding to ICAMs In cis. Cell Rep. 2019 01 02; 26(1):119-130.e5. Fan Z, Kiosses WB, Sun H, Orecchioni M, Ghosheh Y, Zajonc DM, Arnaout MA, Gutierrez E, Groisman A, Ginsberg MH, Ley K. PMID: 30605669; PMCID: PMC6625519.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansCells
    31. Cerebral cavernous malformations form an anticoagulant vascular domain in humans and mice. Blood. 2019 01 17; 133(3):193-204. Lopez-Ramirez MA, Pham A, Girard R, Wyseure T, Hale P, Yamashita A, Koskimäki J, Polster S, Saadat L, Romero IA, Esmon CT, Lagarrigue F, Awad IA, Mosnier LO, Ginsberg MH. PMID: 30442679; PMCID: PMC6337879.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimalsCells
    32. Rap1 binding to the talin 1 F0 domain makes a minimal contribution to murine platelet GPIIb-IIIa activation. Blood Adv. 2018 09 25; 2(18):2358-2368. Lagarrigue F, Gingras AR, Paul DS, Valadez AJ, Cuevas MN, Sun H, Lopez-Ramirez MA, Goult BT, Shattil SJ, Bergmeier W, Ginsberg MH. PMID: 30242097; PMCID: PMC6156890.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    33. Phenotypic characterization of murine models of cerebral cavernous malformations. Lab Invest. 2019 03; 99(3):319-330. Zeineddine HA, Girard R, Saadat L, Shen L, Lightle R, Moore T, Cao Y, Hobson N, Shenkar R, Avner K, Chaudager K, Koskimäki J, Polster SP, Fam MD, Shi C, Lopez-Ramirez MA, Tang AT, Gallione C, Kahn ML, Ginsberg M, Marchuk DA, Awad IA. PMID: 29946133; PMCID: PMC6309944.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    34. Integrin Activation Controls Regulatory T Cell-Mediated Peripheral Tolerance. J Immunol. 2018 06 15; 200(12):4012-4023. Klann JE, Kim SH, Remedios KA, He Z, Metz PJ, Lopez J, Tysl T, Olvera JG, Ablack JN, Cantor JM, Boland BS, Yeo G, Zheng Y, Lu LF, Bui JD, Ginsberg MH, Petrich BG, Chang JT. PMID: 29703862; PMCID: PMC5988969.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    35. Transmission of integrin β7 transmembrane domain topology enables gut lymphoid tissue development. J Cell Biol. 2018 04 02; 217(4):1453-1465. Sun H, Lagarrigue F, Gingras AR, Fan Z, Ley K, Ginsberg MH. PMID: 29535192; PMCID: PMC5881498.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    36. The Therapeutic Antibody LM609 Selectively Inhibits Ligand Binding to Human αVβ3 Integrin via Steric Hindrance. Structure. 2017 11 07; 25(11):1732-1739.e5. Borst AJ, James ZM, Zagotta WN, Ginsberg M, Rey FA, DiMaio F, Backovic M, Veesler D. PMID: 29033288; PMCID: PMC5689087.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    37. Thrombospondin1 (TSP1) replacement prevents cerebral cavernous malformations. J Exp Med. 2017 Nov 06; 214(11):3331-3346. Lopez-Ramirez MA, Fonseca G, Zeineddine HA, Girard R, Moore T, Pham A, Cao Y, Shenkar R, de Kreuk BJ, Lagarrigue F, Lawler J, Glass CK, Awad IA, Ginsberg MH. PMID: 28970240; PMCID: PMC5679163.
      View in: PubMed   Mentions: 53     Fields:    Translation:HumansAnimalsCells
    38. Talin Plays a Critical Role in the Maintenance of the Regulatory T Cell Pool. J Immunol. 2017 06 15; 198(12):4639-4651. Klann JE, Remedios KA, Kim SH, Metz PJ, Lopez J, Mack LA, Zheng Y, Ginsberg MH, Petrich BG, Chang JT. PMID: 28515282; PMCID: PMC5507362.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    39. Tissue Factor Prothrombotic Activity Is Regulated by Integrin-arf6 Trafficking. Arterioscler Thromb Vasc Biol. 2017 07; 37(7):1323-1331. Rothmeier AS, Marchese P, Langer F, Kamikubo Y, Schaffner F, Cantor J, Ginsberg MH, Ruggeri ZM, Ruf W. PMID: 28495929; PMCID: PMC5501484.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    40. Epigallocatechin gallate has pleiotropic effects on transmembrane signaling by altering the embedding of transmembrane domains. J Biol Chem. 2017 06 16; 292(24):9858-9864. Ye F, Yang C, Kim J, MacNevin CJ, Hahn KM, Park D, Ginsberg MH, Kim C. PMID: 28487468; PMCID: PMC5473239.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    41. Cutting Edge: Loss of T Cell RIAM Precludes Conjugate Formation with APC and Prevents Immune-Mediated Diabetes. J Immunol. 2017 05 01; 198(9):3410-3415. Lagarrigue F, Gertler FB, Ginsberg MH, Cantor JM. PMID: 28348273; PMCID: PMC5954999.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    42. CD98 regulates vascular smooth muscle cell proliferation in atherosclerosis. Atherosclerosis. 2017 01; 256:105-114. Baumer Y, McCurdy S, Alcala M, Mehta N, Lee BH, Ginsberg MH, Boisvert WA. PMID: 28012647; PMCID: PMC5276722.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    43. Structural Basis of Dimeric Rasip1 RA Domain Recognition of the Ras Subfamily of GTP-Binding Proteins. Structure. 2016 12 06; 24(12):2152-2162. Gingras AR, Puzon-McLaughlin W, Bobkov AA, Ginsberg MH. PMID: 27839947; PMCID: PMC5143164.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    44. CD98-Mediated Adhesive Signaling Enables the Establishment and Propagation of Acute Myelogenous Leukemia. Cancer Cell. 2016 Nov 14; 30(5):792-805. Bajaj J, Konuma T, Lytle NK, Kwon HY, Ablack JN, Cantor JM, Rizzieri D, Chuah C, Oehler VG, Broome EH, Ball ED, van der Horst EH, Ginsberg MH, Reya T. PMID: 27908736; PMCID: PMC5137811.
      View in: PubMed   Mentions: 62     Fields:    Translation:HumansAnimalsCells
    45. Neutrophil recruitment limited by high-affinity bent β2 integrin binding ligand in cis. Nat Commun. 2016 08 31; 7:12658. Fan Z, McArdle S, Marki A, Mikulski Z, Gutierrez E, Engelhardt B, Deutsch U, Ginsberg M, Groisman A, Ley K. PMID: 27578049; PMCID: PMC5013657.
      View in: PubMed   Mentions: 65     Fields:    Translation:HumansAnimalsCells
    46. Enhanced Integrin α4β1-Mediated Adhesion Contributes to a Mobilization Defect of Endothelial Progenitor Cells in Diabetes. Diabetes. 2016 Nov; 65(11):3505-3515. Abplanalp WT, Conklin DJ, Cantor JM, Ginsberg MH, Wysoczynski M, Bhatnagar A, O'Toole TE. PMID: 27495221; PMCID: PMC5079633.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    47. A Conserved Ectodomain-Transmembrane Domain Linker Motif Tunes the Allosteric Regulation of Cell Surface Receptors. J Biol Chem. 2016 08 19; 291(34):17536-46. Schmidt T, Ye F, Situ AJ, An W, Ginsberg MH, Ulmer TS. PMID: 27365391; PMCID: PMC5016151.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    48. The Rap1-RIAM-talin axis of integrin activation and blood cell function. Blood. 2016 07 28; 128(4):479-87. Lagarrigue F, Kim C, Ginsberg MH. PMID: 27207789; PMCID: PMC4965904.
      View in: PubMed   Mentions: 74     Fields:    Translation:HumansCells
    49. Amino Acid Transport Associated to Cluster of Differentiation 98 Heavy Chain (CD98hc) Is at the Cross-road of Oxidative Stress and Amino Acid Availability. J Biol Chem. 2016 Apr 29; 291(18):9700-11. de la Ballina LR, Cano-Crespo S, González-Muñoz E, Bial S, Estrach S, Cailleteau L, Tissot F, Daniel H, Zorzano A, Ginsberg MH, Palacín M, Féral CC. PMID: 26945935; PMCID: PMC4850307.
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    50. Heart of glass anchors Rasip1 at endothelial cell-cell junctions to support vascular integrity. Elife. 2016 Jan 19; 5:e11394. de Kreuk BJ, Gingras AR, Knight JD, Liu JJ, Gingras AC, Ginsberg MH. PMID: 26780829; PMCID: PMC4733052.
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    51. Ubiquitylation of CD98 limits cell proliferation and clonal expansion. J Cell Sci. 2015 Dec 01; 128(23):4273-8. Ablack JN, Metz PJ, Chang JT, Cantor JM, Ginsberg MH. PMID: 26493331; PMCID: PMC4712820.
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    52. RLIP76 regulates Arf6-dependent cell spreading and migration by linking ARNO with activated R-Ras at recycling endosomes. Biochem Biophys Res Commun. 2015 Nov 27; 467(4):785-91. Wurtzel JG, Lee S, Singhal SS, Awasthi S, Ginsberg MH, Goldfinger LE. PMID: 26498519; PMCID: PMC4644438.
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    53. A RIAM/lamellipodin-talin-integrin complex forms the tip of sticky fingers that guide cell migration. Nat Commun. 2015 Sep 30; 6:8492. Lagarrigue F, Vikas Anekal P, Lee HS, Bachir AI, Ablack JN, Horwitz AF, Ginsberg MH. PMID: 26419705; PMCID: PMC4589889.
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    54. The Structure of a Full-length Membrane-embedded Integrin Bound to a Physiological Ligand. J Biol Chem. 2015 Nov 06; 290(45):27168-27175. Dai A, Ye F, Taylor DW, Hu G, Ginsberg MH, Taylor KA. PMID: 26391523; PMCID: PMC4646401.
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    55. An Isoform-Specific Myristylation Switch Targets Type II PKA Holoenzymes to Membranes. Structure. 2015 Sep 01; 23(9):1563-1572. Zhang P, Ye F, Bastidas AC, Kornev AP, Wu J, Ginsberg MH, Taylor SS. PMID: 26278174; PMCID: PMC4558360.
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    56. Blocking neutrophil integrin activation prevents ischemia-reperfusion injury. J Exp Med. 2015 Jul 27; 212(8):1267-81. Yago T, Petrich BG, Zhang N, Liu Z, Shao B, Ginsberg MH, McEver RP. PMID: 26169939; PMCID: PMC4516797.
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    57. Caspase-1-mediated pathway promotes generation of thromboinflammatory microparticles. J Clin Invest. 2015 Apr; 125(4):1471-84. Rothmeier AS, Marchese P, Petrich BG, Furlan-Freguia C, Ginsberg MH, Ruggeri ZM, Ruf W. PMID: 25705884; PMCID: PMC4396490.
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    58. Annular anionic lipids stabilize the integrin αIIbβ3 transmembrane complex. J Biol Chem. 2015 Mar 27; 290(13):8283-93. Schmidt T, Suk JE, Ye F, Situ AJ, Mazumder P, Ginsberg MH, Ulmer TS. PMID: 25632962; PMCID: PMC4375483.
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    59. Fine-tuning Tumor Immunity with Integrin Trans-regulation. Cancer Immunol Res. 2015 Jun; 3(6):661-7. Cantor JM, Rose DM, Slepak M, Ginsberg MH. PMID: 25600437; PMCID: PMC5955000.
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    60. Antitumor activity of an anti-CD98 antibody. Int J Cancer. 2015 Aug 01; 137(3):710-20. Hayes GM, Chinn L, Cantor JM, Cairns B, Levashova Z, Tran H, Velilla T, Duey D, Lippincott J, Zachwieja J, Ginsberg MH, H van der Horst E. PMID: 25556716; PMCID: PMC6680144.
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    61. Interaction of kindlin-2 with integrin β3 promotes outside-in signaling responses by the αVβ3 vitronectin receptor. Blood. 2015 Mar 19; 125(12):1995-2004. Liao Z, Kato H, Pandey M, Cantor JM, Ablooglu AJ, Ginsberg MH, Shattil SJ. PMID: 25587038; PMCID: PMC4366628.
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    62. Integrin activation. BMB Rep. 2014 Dec; 47(12):655-9. Ginsberg MH. PMID: 25388208; PMCID: PMC4345508.
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    63. CD98hc (SLC3A2) loss protects against ras-driven tumorigenesis by modulating integrin-mediated mechanotransduction. Cancer Res. 2014 Dec 01; 74(23):6878-89. Estrach S, Lee SA, Boulter E, Pisano S, Errante A, Tissot FS, Cailleteau L, Pons C, Ginsberg MH, Féral CC. PMID: 25267066; PMCID: PMC5120678.
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    64. SnapShot: talin and the modular nature of the integrin adhesome. Cell. 2014 Mar 13; 156(6):1340-1340.e1. Ye F, Lagarrigue F, Ginsberg MH. PMID: 24630731; PMCID: PMC4479492.
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    65. ADAP interactions with talin and kindlin promote platelet integrin αIIbβ3 activation and stable fibrinogen binding. Blood. 2014 May 15; 123(20):3156-65. Kasirer-Friede A, Kang J, Kahner B, Ye F, Ginsberg MH, Shattil SJ. PMID: 24523237; PMCID: PMC4023421.
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    66. Talin and kindlin: the one-two punch in integrin activation. Front Med. 2014 Mar; 8(1):6-16. Ye F, Snider AK, Ginsberg MH. PMID: 24477625.
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    67. High mutation detection rates in cerebral cavernous malformation upon stringent inclusion criteria: one-third of probands are minors. Mol Genet Genomic Med. 2014 Mar; 2(2):176-85. Spiegler S, Najm J, Liu J, Gkalympoudis S, Schröder W, Borck G, Brockmann K, Elbracht M, Fauth C, Ferbert A, Freudenberg L, Grasshoff U, Hellenbroich Y, Henn W, Hoffjan S, Hüning I, Korenke GC, Kroisel PM, Kunstmann E, Mair M, Munk-Schulenburg S, Nikoubashman O, Pauli S, Rudnik-Schöneborn S, Sudholt I, Sure U, Tinschert S, Wiednig M, Zoll B, Ginsberg MH, Felbor U. PMID: 24689081; PMCID: PMC3960060.
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    69. The nucleus of endothelial cell as a sensor of blood flow direction. Biol Open. 2013; 2(10):1007-12. Tkachenko E, Gutierrez E, Saikin SK, Fogelstrand P, Kim C, Groisman A, Ginsberg MH. PMID: 24167710; PMCID: PMC3798183.
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    70. The structure of the ternary complex of Krev interaction trapped 1 (KRIT1) bound to both the Rap1 GTPase and the heart of glass (HEG1) cytoplasmic tail. J Biol Chem. 2013 Aug 16; 288(33):23639-49. Gingras AR, Puzon-McLaughlin W, Ginsberg MH. PMID: 23814056; PMCID: PMC3745310.
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    73. Talin1 and Rap1 are critical for osteoclast function. Mol Cell Biol. 2013 Feb; 33(4):830-44. Zou W, Izawa T, Zhu T, Chappel J, Otero K, Monkley SJ, Critchley DR, Petrich BG, Morozov A, Ginsberg MH, Teitelbaum SL. PMID: 23230271; PMCID: PMC3571341.
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    76. Talin activates integrins by altering the topology of the β transmembrane domain. J Cell Biol. 2012 May 28; 197(5):605-11. Kim C, Ye F, Hu X, Ginsberg MH. PMID: 22641344; PMCID: PMC3365499.
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    78. Distinct roles for talin-1 and kindlin-3 in LFA-1 extension and affinity regulation. Blood. 2012 May 03; 119(18):4275-82. Lefort CT, Rossaint J, Moser M, Petrich BG, Zarbock A, Monkley SJ, Critchley DR, Ginsberg MH, Fässler R, Ley K. PMID: 22431571; PMCID: PMC3359742.
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    79. CD98 at the crossroads of adaptive immunity and cancer. J Cell Sci. 2012 Mar 15; 125(Pt 6):1373-82. Cantor JM, Ginsberg MH. PMID: 22499670; PMCID: PMC3336374.
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    80. Subcellular localization of talin is regulated by inter-domain interactions. J Biol Chem. 2012 Apr 20; 287(17):13799-812. Banno A, Goult BT, Lee H, Bate N, Critchley DR, Ginsberg MH. PMID: 22351767; PMCID: PMC3340173.
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    81. Basic amino-acid side chains regulate transmembrane integrin signalling. Nature. 2011 Dec 18; 481(7380):209-13. Kim C, Schmidt T, Cho EG, Ye F, Ulmer TS, Ginsberg MH. PMID: 22178926; PMCID: PMC3257387.
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    82. Phosphorylation sites in the cerebral cavernous malformations complex. J Cell Sci. 2011 Dec 01; 124(Pt 23):3929-32. Kim J, Sherman NE, Fox JW, Ginsberg MH. PMID: 22194303; PMCID: PMC3244978.
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    83. Fasudil decreases lesion burden in a murine model of cerebral cavernous malformation disease. Stroke. 2012 Feb; 43(2):571-4. McDonald DA, Shi C, Shenkar R, Stockton RA, Liu F, Ginsberg MH, Marchuk DA, Awad IA. PMID: 22034008; PMCID: PMC3265629.
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    87. Molecular mechanism of inside-out integrin regulation. J Thromb Haemost. 2011 Jul; 9 Suppl 1:20-25. Ye F, Kim C, Ginsberg MH. PMID: 21781238; PMCID: PMC3979599.
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    94. Endothelial cell talin1 is essential for embryonic angiogenesis. Dev Biol. 2011 Jan 15; 349(2):494-502. Monkley SJ, Kostourou V, Spence L, Petrich B, Coleman S, Ginsberg MH, Pritchard CA, Critchley DR. PMID: 21081121; PMCID: PMC3025397.
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    99. A small molecule that inhibits the interaction of paxillin and alpha 4 integrin inhibits accumulation of mononuclear leukocytes at a site of inflammation. J Biol Chem. 2010 Mar 26; 285(13):9462-9469. Kummer C, Petrich BG, Rose DM, Ginsberg MH. PMID: 20097761; PMCID: PMC2843196.
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    104. Dependence of proliferative vascular smooth muscle cells on CD98hc (4F2hc, SLC3A2). J Exp Med. 2009 Oct 26; 206(11):2397-406. Fogelstrand P, Féral CC, Zargham R, Ginsberg MH. PMID: 19841087; PMCID: PMC2768859.
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    105. Slit2-Robo4 signalling promotes vascular stability by blocking Arf6 activity. Nat Cell Biol. 2009 Nov; 11(11):1325-31. Jones CA, Nishiya N, London NR, Zhu W, Sorensen LK, Chan AC, Lim CJ, Chen H, Zhang Q, Schultz PG, Hayallah AM, Thomas KR, Famulok M, Zhang K, Ginsberg MH, Li DY. PMID: 19855388; PMCID: PMC2854659.
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    120. Localized alpha4 integrin phosphorylation directs shear stress-induced endothelial cell alignment. Circ Res. 2008 Jul 18; 103(2):177-85. Goldfinger LE, Tzima E, Stockton R, Kiosses WB, Kinbara K, Tkachenko E, Gutierrez E, Groisman A, Nguyen P, Chien S, Ginsberg MH. PMID: 18583710; PMCID: PMC2669779.
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    121. Mechanisms and consequences of agonist-induced talin recruitment to platelet integrin alphaIIbbeta3. J Cell Biol. 2008 Jun 30; 181(7):1211-22. Watanabe N, Bodin L, Pandey M, Krause M, Coughlin S, Boussiotis VA, Ginsberg MH, Shattil SJ. PMID: 18573917; PMCID: PMC2442211.
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    122. Integrin-associated proteins as potential therapeutic targets. Immunol Rev. 2008 Jun; 223:236-51. Cantor JM, Ginsberg MH, Rose DM. PMID: 18613840.
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    123. Differences in regulation of Drosophila and vertebrate integrin affinity by talin. Mol Biol Cell. 2008 Aug; 19(8):3589-98. Helsten TL, Bunch TA, Kato H, Yamanouchi J, Choi SH, Jannuzi AL, Féral CC, Ginsberg MH, Brower DL, Shattil SJ. PMID: 18508915; PMCID: PMC2488300.
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    124. Blockade of alpha4 integrin signaling ameliorates the metabolic consequences of high-fat diet-induced obesity. Diabetes. 2008 Jul; 57(7):1842-51. Féral CC, Neels JG, Kummer C, Slepak M, Olefsky JM, Ginsberg MH. PMID: 18426864; PMCID: PMC2453617.
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    125. Integrin activation. Biochem Soc Trans. 2008 Apr; 36(Pt 2):229-34. Banno A, Ginsberg MH. PMID: 18363565; PMCID: PMC2588347.
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    126. Robo4 stabilizes the vascular network by inhibiting pathologic angiogenesis and endothelial hyperpermeability. Nat Med. 2008 Apr; 14(4):448-53. Jones CA, London NR, Chen H, Park KW, Sauvaget D, Stockton RA, Wythe JD, Suh W, Larrieu-Lahargue F, Mukouyama YS, Lindblom P, Seth P, Frias A, Nishiya N, Ginsberg MH, Gerhardt H, Zhang K, Li DY. PMID: 18345009; PMCID: PMC2875252.
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    127. Structure of the integrin beta3 transmembrane segment in phospholipid bicelles and detergent micelles. Biochemistry. 2008 Apr 01; 47(13):4008-16. Lau TL, Partridge AW, Ginsberg MH, Ulmer TS. PMID: 18321071.
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    128. A small molecule inhibitor of alpha4 integrin-dependent cell migration. Bioorg Med Chem. 2009 Feb 01; 17(3):977-80. Lee J, Hong J, Nam TG, Peters EC, Orth AP, Geierstanger BH, Goldfinger LE, Ginsberg MH, Cho CY, Schultz PG. PMID: 18329275; PMCID: PMC2951142.
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    129. Talin is required for integrin-mediated platelet function in hemostasis and thrombosis. J Exp Med. 2007 Dec 24; 204(13):3103-11. Petrich BG, Marchese P, Ruggeri ZM, Spiess S, Weichert RA, Ye F, Tiedt R, Skoda RC, Monkley SJ, Critchley DR, Ginsberg MH. PMID: 18086863; PMCID: PMC2150986.
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    130. KRIT-1/CCM1 is a Rap1 effector that regulates endothelial cell cell junctions. J Cell Biol. 2007 Oct 22; 179(2):247-54. Glading A, Han J, Stockton RA, Ginsberg MH. PMID: 17954608; PMCID: PMC2064761.
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    131. CD98hc (SLC3A2) participates in fibronectin matrix assembly by mediating integrin signaling. J Cell Biol. 2007 Aug 13; 178(4):701-11. Féral CC, Zijlstra A, Tkachenko E, Prager G, Gardel ML, Slepak M, Ginsberg MH. PMID: 17682053; PMCID: PMC2064475.
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    132. Integrin modulation and signaling in leukocyte adhesion and migration. Immunol Rev. 2007 Aug; 218:126-34. Rose DM, Alon R, Ginsberg MH. PMID: 17624949.
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    133. The antithrombotic potential of selective blockade of talin-dependent integrin alpha IIb beta 3 (platelet GPIIb-IIIa) activation. J Clin Invest. 2007 Aug; 117(8):2250-9. Petrich BG, Fogelstrand P, Partridge AW, Yousefi N, Ablooglu AJ, Shattil SJ, Ginsberg MH. PMID: 17627302; PMCID: PMC1906732.
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    134. Neurite outgrowth on a fibronectin isoform expressed during peripheral nerve regeneration is mediated by the interaction of paxillin with alpha4beta1 integrins. BMC Neurosci. 2007 Jun 29; 8:44. Vogelezang M, Forster UB, Han J, Ginsberg MH, ffrench-Constant C. PMID: 17603879; PMCID: PMC1940015.
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    135. CD98hc (SLC3A2) interaction with the integrin beta subunit cytoplasmic domain mediates adhesive signaling. J Biol Chem. 2007 Aug 17; 282(33):24477-84. Prager GW, Féral CC, Kim C, Han J, Ginsberg MH. PMID: 17597067.
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    136. Small-molecule synergist of the Wnt/beta-catenin signaling pathway. Proc Natl Acad Sci U S A. 2007 May 01; 104(18):7444-8. Zhang Q, Major MB, Takanashi S, Camp ND, Nishiya N, Peters EC, Ginsberg MH, Jian X, Randazzo PA, Schultz PG, Moon RT, Ding S. PMID: 17460038; PMCID: PMC1863490.
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    137. An experimentally derived database of candidate Ras-interacting proteins. J Proteome Res. 2007 May; 6(5):1806-11. Goldfinger LE, Ptak C, Jeffery ED, Shabanowitz J, Han J, Haling JR, Sherman NE, Fox JW, Hunt DF, Ginsberg MH. PMID: 17439166; PMCID: PMC4627692.
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    138. Alpha4 integrins are type I cAMP-dependent protein kinase-anchoring proteins. Nat Cell Biol. 2007 Apr; 9(4):415-21. Lim CJ, Han J, Yousefi N, Ma Y, Amieux PS, McKnight GS, Taylor SS, Ginsberg MH. PMID: 17369818.
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    139. Syk, c-Src, the alphavbeta3 integrin, and ITAM immunoreceptors, in concert, regulate osteoclastic bone resorption. J Cell Biol. 2007 Mar 12; 176(6):877-88. Zou W, Kitaura H, Reeve J, Long F, Tybulewicz VL, Shattil SJ, Ginsberg MH, Ross FP, Teitelbaum SL. PMID: 17353363; PMCID: PMC2064061.
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    140. PEA-15 inhibits tumor cell invasion by binding to extracellular signal-regulated kinase 1/2. Cancer Res. 2007 Feb 15; 67(4):1536-44. Glading A, Koziol JA, Krueger J, Ginsberg MH. PMID: 17308092.
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    141. Structural basis of integrin activation by talin. Cell. 2007 Jan 12; 128(1):171-82. Wegener KL, Partridge AW, Han J, Pickford AR, Liddington RC, Ginsberg MH, Campbell ID. PMID: 17218263.
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    142. Reconstructing and deconstructing agonist-induced activation of integrin alphaIIbbeta3. Curr Biol. 2006 Sep 19; 16(18):1796-806. Han J, Lim CJ, Watanabe N, Soriani A, Ratnikov B, Calderwood DA, Puzon-McLaughlin W, Lafuente EM, Boussiotis VA, Shattil SJ, Ginsberg MH. PMID: 16979556.
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    143. RLIP76 (RalBP1) is an R-Ras effector that mediates adhesion-dependent Rac activation and cell migration. J Cell Biol. 2006 Sep 11; 174(6):877-88. Goldfinger LE, Ptak C, Jeffery ED, Shabanowitz J, Hunt DF, Ginsberg MH. PMID: 16966426; PMCID: PMC2064341.
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    144. Matrix-specific suppression of integrin activation in shear stress signaling. Mol Biol Cell. 2006 Nov; 17(11):4686-97. Orr AW, Ginsberg MH, Shattil SJ, Deckmyn H, Schwartz MA. PMID: 16928957; PMCID: PMC1635406.
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    145. Phospholipase C epsilon suppresses integrin activation. J Biol Chem. 2006 Oct 06; 281(40):29501-12. Lad Y, McHugh B, Hodkinson PS, Mackinnon AC, Haslett C, Ginsberg MH, Sethi T. PMID: 16895916.
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    146. New approaches to blockade of alpha4-integrins, proven therapeutic targets in chronic inflammation. Biochem Pharmacol. 2006 Nov 30; 72(11):1460-8. Kummer C, Ginsberg MH. PMID: 16870156.
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    147. Blocking the alpha 4 integrin-paxillin interaction selectively impairs mononuclear leukocyte recruitment to an inflammatory site. J Clin Invest. 2006 Mar; 116(3):715-23. Féral CC, Rose DM, Han J, Fox N, Silverman GJ, Kaushansky K, Ginsberg MH. PMID: 16470243; PMCID: PMC1361348.
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    148. Antitumor effect of E1A in ovarian cancer by cytoplasmic sequestration of activated ERK by PEA15. Oncogene. 2006 Jan 05; 25(1):79-90. Bartholomeusz C, Itamochi H, Nitta M, Saya H, Ginsberg MH, Ueno NT. PMID: 16170361.
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    149. Alpha4beta1-dependent adhesion strengthening under mechanical strain is regulated by paxillin association with the alpha4-cytoplasmic domain. J Cell Biol. 2005 Dec 19; 171(6):1073-84. Alon R, Feigelson SW, Manevich E, Rose DM, Schmitz J, Overby DR, Winter E, Grabovsky V, Shinder V, Matthews BD, Sokolovsky-Eisenberg M, Ingber DE, Benoit M, Ginsberg MH. PMID: 16365170; PMCID: PMC2171310.
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    150. Talin phosphorylation sites mapped by mass spectrometry. J Cell Sci. 2005 Nov 01; 118(Pt 21):4921-3. Ratnikov B, Ptak C, Han J, Shabanowitz J, Hunt DF, Ginsberg MH. PMID: 16254238.
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    151. Integrin alpha4beta1 promotes focal adhesion kinase-independent cell motility via alpha4 cytoplasmic domain-specific activation of c-Src. Mol Cell Biol. 2005 Nov; 25(21):9700-12. Hsia DA, Lim ST, Bernard-Trifilo JA, Mitra SK, Tanaka S, den Hertog J, Streblow DN, Ilic D, Ginsberg MH, Schlaepfer DD. PMID: 16227616; PMCID: PMC1265817.
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    152. Integrin regulation. Curr Opin Cell Biol. 2005 Oct; 17(5):509-16. Ginsberg MH, Partridge A, Shattil SJ. PMID: 16099636.
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    153. Integrin activation by talin. J Thromb Haemost. 2005 Aug; 3(8):1783-90. Ratnikov BI, Partridge AW, Ginsberg MH. PMID: 16102045.
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    154. Specification of the direction of adhesive signaling by the integrin beta cytoplasmic domain. J Biol Chem. 2005 Aug 19; 280(33):29699-707. Arias-Salgado EG, Lizano S, Shattil SJ, Ginsberg MH. PMID: 15937333.
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    155. Phosphorylation of phosphoprotein enriched in astrocytes (PEA-15) regulates extracellular signal-regulated kinase-dependent transcription and cell proliferation. Mol Biol Cell. 2005 Aug; 16(8):3552-61. Krueger J, Chou FL, Glading A, Schaefer E, Ginsberg MH. PMID: 15917297; PMCID: PMC1182297.
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    156. An alpha4 integrin-paxillin-Arf-GAP complex restricts Rac activation to the leading edge of migrating cells. Nat Cell Biol. 2005 Apr; 7(4):343-52. Nishiya N, Kiosses WB, Han J, Ginsberg MH. PMID: 15793570.
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    157. CD98hc (SLC3A2) mediates integrin signaling. Proc Natl Acad Sci U S A. 2005 Jan 11; 102(2):355-60. Feral CC, Nishiya N, Fenczik CA, Stuhlmann H, Slepak M, Ginsberg MH. PMID: 15625115; PMCID: PMC544283.
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    158. Structural basis for phosphatidylinositol phosphate kinase type Igamma binding to talin at focal adhesions. J Biol Chem. 2005 Mar 04; 280(9):8381-6. de Pereda JM, Wegener KL, Santelli E, Bate N, Ginsberg MH, Critchley DR, Campbell ID, Liddington RC. PMID: 15623515.
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    159. Transmembrane domain helix packing stabilizes integrin alphaIIbbeta3 in the low affinity state. J Biol Chem. 2005 Feb 25; 280(8):7294-300. Partridge AW, Liu S, Kim S, Bowie JU, Ginsberg MH. PMID: 15591321.
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    160. CD98hc (SLC3A2) interaction with beta 1 integrins is required for transformation. J Biol Chem. 2004 Dec 24; 279(52):54731-41. Henderson NC, Collis EA, Mackinnon AC, Simpson KJ, Haslett C, Zent R, Ginsberg M, Sethi T. PMID: 15485886.
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    161. The talin-tail interaction places integrin activation on FERM ground. Trends Biochem Sci. 2004 Aug; 29(8):429-35. Campbell ID, Ginsberg MH. PMID: 15362227.
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    162. Competition for talin results in trans-dominant inhibition of integrin activation. J Biol Chem. 2004 Jul 09; 279(28):28889-95. Calderwood DA, Tai V, Di Paolo G, De Camilli P, Ginsberg MH. PMID: 15143061.
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    163. Neurobiology: New connections between integrins and axon guidance. Curr Biol. 2004 Feb 03; 14(3):R121-3. Nakamoto T, Kain KH, Ginsberg MH. PMID: 14986683.
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    164. Cell migration: integrating signals from front to back. Science. 2003 Dec 05; 302(5651):1704-9. Ridley AJ, Schwartz MA, Burridge K, Firtel RA, Ginsberg MH, Borisy G, Parsons JT, Horwitz AR. PMID: 14657486.
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    165. C-terminal sequences in R-Ras are involved in integrin regulation and in plasma membrane microdomain distribution. Biochem Biophys Res Commun. 2003 Nov 28; 311(4):829-38. Hansen M, Prior IA, Hughes PE, Oertli B, Chou FL, Willumsen BM, Hancock JF, Ginsberg MH. PMID: 14623256.
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    166. The Kindler syndrome protein is regulated by transforming growth factor-beta and involved in integrin-mediated adhesion. J Biol Chem. 2004 Feb 20; 279(8):6824-33. Kloeker S, Major MB, Calderwood DA, Ginsberg MH, Jones DA, Beckerle MC. PMID: 14634021.
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    167. Src kinase activation by direct interaction with the integrin beta cytoplasmic domain. Proc Natl Acad Sci U S A. 2003 Nov 11; 100(23):13298-302. Arias-Salgado EG, Lizano S, Sarkar S, Brugge JS, Ginsberg MH, Shattil SJ. PMID: 14593208; PMCID: PMC263791.
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    168. Talin binding to integrin beta tails: a final common step in integrin activation. Science. 2003 Oct 03; 302(5642):103-6. Tadokoro S, Shattil SJ, Eto K, Tai V, Liddington RC, de Pereda JM, Ginsberg MH, Calderwood DA. PMID: 14526080.
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    169. Ras GTPases: integrins' friends or foes? Nat Rev Mol Cell Biol. 2003 Oct; 4(10):767-76. Kinbara K, Goldfinger LE, Hansen M, Chou FL, Ginsberg MH. PMID: 14570053.
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    170. PEA-15 binding to ERK1/2 MAPKs is required for its modulation of integrin activation. J Biol Chem. 2003 Dec 26; 278(52):52587-97. Chou FL, Hill JM, Hsieh JC, Pouyssegur J, Brunet A, Glading A, Uberall F, Ramos JW, Werner MH, Ginsberg MH. PMID: 14506247.
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    171. Spatial restriction of alpha4 integrin phosphorylation regulates lamellipodial stability and alpha4beta1-dependent cell migration. J Cell Biol. 2003 Aug 18; 162(4):731-41. Goldfinger LE, Han J, Kiosses WB, Howe AK, Ginsberg MH. PMID: 12913113; PMCID: PMC2173787.
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    172. Talin forges the links between integrins and actin. Nat Cell Biol. 2003 Aug; 5(8):694-7. Calderwood DA, Ginsberg MH. PMID: 12894175.
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    173. Domain-specific interactions of talin with the membrane-proximal region of the integrin beta3 subunit. Biochemistry. 2003 Jul 15; 42(27):8307-12. Ulmer TS, Calderwood DA, Ginsberg MH, Campbell ID. PMID: 12846579.
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    174. Integrin alpha 4 beta 1-dependent T cell migration requires both phosphorylation and dephosphorylation of the alpha 4 cytoplasmic domain to regulate the reversible binding of paxillin. J Biol Chem. 2003 Sep 12; 278(37):34845-53. Han J, Rose DM, Woodside DG, Goldfinger LE, Ginsberg MH. PMID: 12837751.
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    175. Paxillin binding to the alpha 4 integrin subunit stimulates LFA-1 (integrin alpha L beta 2)-dependent T cell migration by augmenting the activation of focal adhesion kinase/proline-rich tyrosine kinase-2. J Immunol. 2003 Jun 15; 170(12):5912-8. Rose DM, Liu S, Woodside DG, Han J, Schlaepfer DD, Ginsberg MH. PMID: 12794117.
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    176. Integrin beta cytoplasmic domain interactions with phosphotyrosine-binding domains: a structural prototype for diversity in integrin signaling. Proc Natl Acad Sci U S A. 2003 Mar 04; 100(5):2272-7. Calderwood DA, Fujioka Y, de Pereda JM, García-Alvarez B, Nakamoto T, Margolis B, McGlade CJ, Liddington RC, Ginsberg MH. PMID: 12606711; PMCID: PMC151330.
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    178. Recognition of ERK MAP kinase by PEA-15 reveals a common docking site within the death domain and death effector domain. EMBO J. 2002 Dec 02; 21(23):6494-504. Hill JM, Vaidyanathan H, Ramos JW, Ginsberg MH, Werner MH. PMID: 12456656; PMCID: PMC136945.
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    179. Blockade of platelet GPIIB-IIIA (Integrin alphaII(b)beta(3)) in flowing human blood leads to passivation of prothrombotic surfaces. Thromb Haemost. 2002 Nov; 88(5):858-64. Riederer MA, Ginsberg MH, Steiner B. PMID: 12428106.
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    180. Inhibitors of cell migration that inhibit intracellular paxillin/alpha4 binding: a well-documented use of positional scanning libraries. Chem Biol. 2002 Nov; 9(11):1219-26. Ambroise Y, Yaspan B, Ginsberg MH, Boger DL. PMID: 12445772.
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    181. Phase II trial of branched peginterferon-alpha 2a (40 kDa) for patients with advanced renal cell carcinoma. Ann Oncol. 2002 Nov; 13(11):1799-805. Motzer RJ, Rakhit A, Thompson J, Gurney H, Selby P, Figlin R, Negrier S, Ernst S, Siebels M, Ginsberg M, Rittweger K, Hooftman L. PMID: 12419754.
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    184. The N-terminal SH2 domains of Syk and ZAP-70 mediate phosphotyrosine-independent binding to integrin beta cytoplasmic domains. J Biol Chem. 2002 Oct 18; 277(42):39401-8. Woodside DG, Obergfell A, Talapatra A, Calderwood DA, Shattil SJ, Ginsberg MH. PMID: 12171941.
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    186. Suppression of integrin activation by activated Ras or Raf does not correlate with bulk activation of ERK MAP kinase. Mol Biol Cell. 2002 Jul; 13(7):2256-65. Hughes PE, Oertli B, Hansen M, Chou FL, Willumsen BM, Ginsberg MH. PMID: 12134066; PMCID: PMC117310.
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    187. R-Ras C-terminal sequences are sufficient to confer R-Ras specificity to H-Ras. Oncogene. 2002 Jun 27; 21(28):4448-61. Hansen M, Rusyn EV, Hughes PE, Ginsberg MH, Cox AD, Willumsen BM. PMID: 12080475.
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    188. Physical mapping of genes in somatic cell radiation hybrids by comparative genomic hybridization to cDNA microarrays. Genome Biol. 2002; 3(6):RESEARCH0026. Lin JY, Pollack JR, Chou FL, Rees CA, Christian AT, Bedford JS, Brown PO, Ginsberg MH. PMID: 12093373; PMCID: PMC116723.
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    189. The phosphotyrosine binding-like domain of talin activates integrins. J Biol Chem. 2002 Jun 14; 277(24):21749-58. Calderwood DA, Yan B, de Pereda JM, Alvarez BG, Fujioka Y, Liddington RC, Ginsberg MH. PMID: 11932255.
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    190. Networks and crosstalk: integrin signalling spreads. Nat Cell Biol. 2002 Apr; 4(4):E65-8. Schwartz MA, Ginsberg MH. PMID: 11944032.
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    192. Expression cloning strategies for the identification of adhesion molecules. Methods Cell Biol. 2002; 69:209-21. Ramos JW, Ginsberg M. PMID: 12070994.
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    193. Increased filamin binding to beta-integrin cytoplasmic domains inhibits cell migration. Nat Cell Biol. 2001 Dec; 3(12):1060-8. Calderwood DA, Huttenlocher A, Kiosses WB, Rose DM, Woodside DG, Schwartz MA, Ginsberg MH. PMID: 11781567.
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    194. Activation of Syk protein tyrosine kinase through interaction with integrin beta cytoplasmic domains. Curr Biol. 2001 Nov 13; 11(22):1799-804. Woodside DG, Obergfell A, Leng L, Wilsbacher JL, Miranti CK, Brugge JS, Shattil SJ, Ginsberg MH. PMID: 11719224.
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    195. Identification of cell signaling molecules by expression cloning. Sci STKE. 2001 Oct 09; 2001(103):pl9. Matter ML, Ginsberg MH, Ramos JW. PMID: 11593050.
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    206. Integrin activation controls metastasis in human breast cancer. Proc Natl Acad Sci U S A. 2001 Feb 13; 98(4):1853-8. Felding-Habermann B, O'Toole TE, Smith JW, Fransvea E, Ruggeri ZM, Ginsberg MH, Hughes PE, Pampori N, Shattil SJ, Saven A, Mueller BM. PMID: 11172040; PMCID: PMC29346.
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    208. Platelet activation by a relapsing fever spirochaete results in enhanced bacterium-platelet interaction via integrin alphaIIbbeta3 activation. Mol Microbiol. 2001 Jan; 39(2):330-40. Alugupalli KR, Michelson AD, Barnard MR, Robbins D, Coburn J, Baker EK, Ginsberg MH, Schwan TG, Leong JM. PMID: 11136454.
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    218. Soluble VCAM-1 binding to alpha4 integrins is cell-type specific and activation dependent and is disrupted during apoptosis in T cells. Blood. 2000 Jan 15; 95(2):602-9. Rose DM, Cardarelli PM, Cobb RR, Ginsberg MH. PMID: 10627469.
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    222. The Talin head domain binds to integrin beta subunit cytoplasmic tails and regulates integrin activation. J Biol Chem. 1999 Oct 01; 274(40):28071-4. Calderwood DA, Zent R, Grant R, Rees DJ, Hynes RO, Ginsberg MH. PMID: 10497155.
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    223. The small GTP-binding protein R-Ras can influence integrin activation by antagonizing a Ras/Raf-initiated integrin suppression pathway. Mol Biol Cell. 1999 Jun; 10(6):1799-809. Sethi T, Ginsberg MH, Downward J, Hughes PE. PMID: 10359597; PMCID: PMC25373.
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    224. Cellular entry of hantaviruses which cause hemorrhagic fever with renal syndrome is mediated by beta3 integrins. J Virol. 1999 May; 73(5):3951-9. Gavrilovskaya IN, Brown EJ, Ginsberg MH, Mackow ER. PMID: 10196290; PMCID: PMC104173.
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    226. A mutation in the alpha subunit of the platelet integrin alphaIIbbeta3 identifies a novel region important for ligand binding. Blood. 1999 Feb 01; 93(3):918-24. Tozer EC, Baker EK, Ginsberg MH, Loftus JC. PMID: 9920841.
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    227. Integrins in the immune system. Adv Immunol. 1999; 72:325-80. Shimizu Y, Rose DM, Ginsberg MH. PMID: 10361579.
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    229. Beta1 integrins participate in the hypertrophic response of rat ventricular myocytes. Circ Res. 1998 Jun 15; 82(11):1160-72. Ross RS, Pham C, Shai SY, Goldhaber JI, Fenczik C, Glembotski CC, Ginsberg MH, Loftus JC. PMID: 9633916.
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    230. beta3 Integrins mediate the cellular entry of hantaviruses that cause respiratory failure. Proc Natl Acad Sci U S A. 1998 Jun 09; 95(12):7074-9. Gavrilovskaya IN, Shepley M, Shaw R, Ginsberg MH, Mackow ER. PMID: 9618541; PMCID: PMC22743.
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    241. Affinity modulation of platelet integrin alphaIIbbeta3 by beta3-endonexin, a selective binding partner of the beta3 integrin cytoplasmic tail. J Cell Biol. 1997 Jun 16; 137(6):1433-43. Kashiwagi H, Schwartz MA, Eigenthaler M, Davis KA, Ginsberg MH, Shattil SJ. PMID: 9182673; PMCID: PMC2132534.
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    245. Integrin-ligand binding properties govern cell migration speed through cell-substratum adhesiveness. Nature. 1997 Feb 06; 385(6616):537-40. Palecek SP, Loftus JC, Ginsberg MH, Lauffenburger DA, Horwitz AF. PMID: 9020360.
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    246. Trans-dominant inhibition of integrin function. Mol Biol Cell. 1996 Dec; 7(12):1939-51. Díaz-González F, Forsyth J, Steiner B, Ginsberg MH. PMID: 8970156; PMCID: PMC276041.
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    247. Cyclic AMP induces apolipoprotein E binding activity and promotes cholesterol efflux from a macrophage cell line to apolipoprotein acceptors. J Biol Chem. 1996 Nov 29; 271(48):30647-55. Smith JD, Miyata M, Ginsberg M, Grigaux C, Shmookler E, Plump AS. PMID: 8940040.
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    254. Cytochrome P450 1A1 promoter as a genetic switch for the regulatable and physiological expression of a plasma protein in transgenic mice. Proc Natl Acad Sci U S A. 1995 Dec 05; 92(25):11926-30. Smith JD, Wong E, Ginsberg M. PMID: 8524876; PMCID: PMC40516.
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    279. Stimulation of integrin-mediated adhesion of T lymphocytes and monocytes: two mechanisms with divergent biological consequences. J Exp Med. 1994 Apr 01; 179(4):1307-16. Faull RJ, Kovach NL, Harlan JM, Ginsberg MH. PMID: 7511685; PMCID: PMC2191445.
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    280. The inner world of cell adhesion: integrin cytoplasmic domains. Trends Cell Biol. 1994 Apr; 4(4):109-12. Williams MJ, Hughes PE, O'Toole TE, Ginsberg MH. PMID: 14731732.
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    281. Integrin cytoplasmic domains mediate inside-out signal transduction. J Cell Biol. 1994 Mar; 124(6):1047-59. O'Toole TE, Katagiri Y, Faull RJ, Peter K, Tamura R, Quaranta V, Loftus JC, Shattil SJ, Ginsberg MH. PMID: 7510712; PMCID: PMC2119979.
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    282. Receptors on platelets. Methods Enzymol. 1994; 245:183-94. Faull RJ, Du X, Ginsberg MH. PMID: 7760734.
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    283. Long range propagation of conformational changes in integrin alpha IIb beta 3. J Biol Chem. 1993 Nov 05; 268(31):23087-92. Du X, Gu M, Weisel JW, Nagaswami C, Bennett JS, Bowditch R, Ginsberg MH. PMID: 7693683.
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    284. Conformational changes in fibrinogen elicited by its interaction with platelet membrane glycoprotein GPIIb-IIIa. J Biol Chem. 1993 Oct 05; 268(28):21080-7. Ugarova TP, Budzynski AZ, Shattil SJ, Ruggeri ZM, Ginsberg MH, Plow EF. PMID: 7691805.
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    285. Adhesive ligand binding to integrin alpha IIb beta 3 stimulates tyrosine phosphorylation of novel protein substrates before phosphorylation of pp125FAK. J Cell Biol. 1993 Jul; 122(2):473-83. Huang MM, Lipfert L, Cunningham M, Brugge JS, Ginsberg MH, Shattil SJ. PMID: 7686553; PMCID: PMC2119653.
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    286. Platelet integrins. Thromb Haemost. 1993 Jul 01; 70(1):87-93. Ginsberg MH, Xiaoping D, O'Toole TE, Loftus JC, Plow EF. PMID: 8236121.
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    287. Distinct functions of integrin alpha and beta subunit cytoplasmic domains in cell spreading and formation of focal adhesions. J Cell Biol. 1993 Jul; 122(1):223-33. Ylänne J, Chen Y, O'Toole TE, Loftus JC, Takada Y, Ginsberg MH. PMID: 8314843; PMCID: PMC2119619.
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    288. Affinity modulation of integrin alpha 5 beta 1: regulation of the functional response by soluble fibronectin. J Cell Biol. 1993 Apr; 121(1):155-62. Faull RJ, Kovach NL, Harlan JM, Ginsberg MH. PMID: 8458867; PMCID: PMC2119780.
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    289. Determination of adhesion force between single cell pairs generated by activated GpIIb-IIIa receptors. Blood. 1993 Jan 15; 81(2):419-23. Sung KL, Frojmovic MM, O'Toole TE, Zhu C, Ginsberg MH, Chien S. PMID: 8422461.
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    290. Characterization of a gain of function mutation of integrin alpha IIb beta 3 (platelet glycoprotein IIb-IIIa). J Biol Chem. 1992 Nov 05; 267(31):22211-6. Bajt ML, Loftus JC, Gawaz MP, Ginsberg MH. PMID: 1429573.
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    291. A point mutation of integrin beta 1 subunit blocks binding of alpha 5 beta 1 to fibronectin and invasin but not recruitment to adhesion plaques. J Cell Biol. 1992 Nov; 119(4):913-21. Takada Y, Ylänne J, Mandelman D, Puzon W, Ginsberg MH. PMID: 1385446; PMCID: PMC2289695.
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    292. Inside-out integrin signalling. Curr Opin Cell Biol. 1992 Oct; 4(5):766-71. Ginsberg MH, Du X, Plow EF. PMID: 1419055.
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    293. Molecular cloning and preliminary characterization of a novel cytoplasmic antigen recognized by myasthenia gravis sera. J Clin Invest. 1992 Sep; 90(3):992-9. Gordon T, Grove B, Loftus JC, O'Toole T, McMillan R, Lindstrom J, Ginsberg MH. PMID: 1522245; PMCID: PMC329955.
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    294. Consequences of the interaction of platelet membrane glycoprotein GPIIb-IIIa (alpha IIb beta 3) and its ligands. J Lab Clin Med. 1992 Aug; 120(2):198-204. Plow EF, D'Souza SE, Ginsberg MH. PMID: 1500819.
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    295. Different specificities of platelet-associated and plasma autoantibodies to platelet GPIIb-IIIa in patients with chronic immune thrombocytopenic purpura. Blood. 1992 Mar 15; 79(6):1441-6. Fujisawa K, Tani P, O'Toole TE, Ginsberg MH, McMillan R. PMID: 1547343.
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    296. A spontaneous mutation of integrin alpha IIb beta 3 (platelet glycoprotein IIb-IIIa) helps define a ligand binding site. J Biol Chem. 1992 Feb 25; 267(6):3789-94. Bajt ML, Ginsberg MH, Frelinger AL, Berndt MC, Loftus JC. PMID: 1371279.
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    297. Localization of a PlA1 epitope to the amino terminal 66 residues of platelet glycoprotein IIIa. Blood. 1992 Feb 01; 79(3):559-62. Bowditch RD, Tani PH, Halloran CE, Frelinger AL, McMillan R, Ginsberg MH. PMID: 1370635.
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    298. Fibronectin binding to platelets. Methods Enzymol. 1992; 215:311-6. Forsyth J, Plow EF, Ginsberg MH. PMID: 1435331.
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    299. Ligand binding to integrins: dynamic regulation and common mechanisms. Cold Spring Harb Symp Quant Biol. 1992; 57:221-31. Ginsberg MH, O'Toole TE, Loftus JC, Plow EF. PMID: 1339661.
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    300. Ligand binding to GPIIb-IIIa: a status report. Semin Thromb Hemost. 1992; 18(3):324-32. Plow EF, D'Souza SE, Ginsberg MH. PMID: 1455250.
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    301. Integrin alpha IIb beta 3 (platelet GPIIb-IIIa) recognizes multiple sites in fibronectin. J Biol Chem. 1991 Dec 05; 266(34):23323-8. Bowditch RD, Halloran CE, Aota S, Obara M, Plow EF, Yamada KM, Ginsberg MH. PMID: 1720779.
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    302. Modulation of the affinity of integrin alpha IIb beta 3 (GPIIb-IIIa) by the cytoplasmic domain of alpha IIb. Science. 1991 Nov 08; 254(5033):845-7. O'Toole TE, Mandelman D, Forsyth J, Shattil SJ, Plow EF, Ginsberg MH. PMID: 1948065.
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    303. Molecular cloning and expression of the cDNA for alpha 3 subunit of human alpha 3 beta 1 (VLA-3), an integrin receptor for fibronectin, laminin, and collagen. J Cell Biol. 1991 Oct; 115(1):257-66. Takada Y, Murphy E, Pil P, Chen C, Ginsberg MH, Hemler ME. PMID: 1655803; PMCID: PMC2289928.
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    304. Ligand bridging mediates integrin alpha IIb beta 3 (platelet GPIIB-IIIA) dependent homotypic and heterotypic cell-cell interactions. J Clin Invest. 1991 Oct; 88(4):1128-34. Gawaz MP, Loftus JC, Bajt ML, Frojmovic MM, Plow EF, Ginsberg MH. PMID: 1918367; PMCID: PMC295567.
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    305. Monoclonal antibodies to ligand-occupied conformers of integrin alpha IIb beta 3 (glycoprotein IIb-IIIa) alter receptor affinity, specificity, and function. J Biol Chem. 1991 Sep 15; 266(26):17106-11. Frelinger AL, Du XP, Plow EF, Ginsberg MH. PMID: 1894607.
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    306. A receptor-induced binding site in fibrinogen elicited by its interaction with platelet membrane glycoprotein IIb-IIIa. J Biol Chem. 1991 Aug 25; 266(24):16193-9. Zamarron C, Ginsberg MH, Plow EF. PMID: 1714910.
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    307. Effect of chemical conjugation of recombinant single-chain urokinase-type plasminogen activator with monoclonal antiplatelet antibodies on platelet aggregation and on plasma clot lysis in vitro and in vivo. Blood. 1991 Aug 15; 78(4):1005-18. Dewerchin M, Lijnen HR, Stassen JM, De Cock F, Quertermous T, Ginsberg MH, Plow EF, Collen D. PMID: 1831057.
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    308. Platelet glycoprotein IIb-IIIa (alpha IIb beta 3 integrin) confers fibrinogen- and activation-dependent aggregation on heterologous cells. Blood. 1991 Jul 15; 78(2):369-76. Frojmovic MM, O'Toole TE, Plow EF, Loftus JC, Ginsberg MH. PMID: 2070074.
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    309. Arginyl-glycyl-aspartic acid (RGD): a cell adhesion motif. Trends Biochem Sci. 1991 Jul; 16(7):246-50. D'Souza SE, Ginsberg MH, Plow EF. PMID: 1926332.
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    310. Autoantibodies to the presumptive cytoplasmic domain of platelet glycoprotein IIIa in patients with chronic immune thrombocytopenic purpura. Blood. 1991 May 15; 77(10):2207-13. Fujisawa K, O'Toole TE, Tani P, Loftus JC, Plow EF, Ginsberg MH, McMillan R. PMID: 1709376.
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    311. Ligands "activate" integrin alpha IIb beta 3 (platelet GPIIb-IIIa). Cell. 1991 May 03; 65(3):409-16. Du XP, Plow EF, Frelinger AL, O'Toole TE, Loftus JC, Ginsberg MH. PMID: 2018974.
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    312. Effect of platelet activation on the conformation of the plasma membrane glycoprotein IIb-IIIa complex. J Biol Chem. 1991 Apr 25; 266(12):7345-52. Sims PJ, Ginsberg MH, Plow EF, Shattil SJ. PMID: 1902217.
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    313. A discrete sequence in a platelet integrin is involved in ligand recognition. Nature. 1991 Mar 07; 350(6313):66-8. D'Souza SE, Ginsberg MH, Matsueda GR, Plow EF. PMID: 2002847.
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    314. Common and ligand-specific integrin recognition mechanisms. Chem Immunol. 1991; 50:75-88. Ginsberg MH, Loftus JC, Plow EF. PMID: 1786108.
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    315. Effects of OKM5, a monoclonal antibody to glycoprotein IV, on platelet aggregation and thrombospondin surface expression. Blood. 1990 Dec 15; 76(12):2501-9. Aiken ML, Ginsberg MH, Byers-Ward V, Plow EF. PMID: 1702328.
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    316. Ligand binding to integrins: common and ligand specific recognition mechanisms. Cell Differ Dev. 1990 Dec 02; 32(3):203-13. Ginsberg MH, Loftus JC, D'Souza S, Plow EF. PMID: 2099237.
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    317. Analysis of platelet aggregation disorders based on flow cytometric analysis of membrane glycoprotein IIb-IIIa with conformation-specific monoclonal antibodies. Blood. 1990 Nov 15; 76(10):2017-23. Ginsberg MH, Frelinger AL, Lam SC, Forsyth J, McMillan R, Plow EF, Shattil SJ. PMID: 2242424.
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    318. Affinity modulation of the alpha IIb beta 3 integrin (platelet GPIIb-IIIa) is an intrinsic property of the receptor. Cell Regul. 1990 Nov; 1(12):883-93. O'Toole TE, Loftus JC, Du XP, Glass AA, Ruggeri ZM, Shattil SJ, Plow EF, Ginsberg MH. PMID: 2100193; PMCID: PMC362859.
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    319. Glycosaminoglycans alter the capacity of low density lipoprotein to bind to monosodium urate crystals. J Rheumatol. 1990 Sep; 17(9):1211-6. Terkeltaub R, Martin J, Curtiss LK, Ginsberg MH. PMID: 2290164.
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    320. A beta 3 integrin mutation abolishes ligand binding and alters divalent cation-dependent conformation. Science. 1990 Aug 24; 249(4971):915-8. Loftus JC, O'Toole TE, Plow EF, Glass A, Frelinger AL, Ginsberg MH. PMID: 2392682.
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    321. Monoclonal antibodies specific for a conformationally altered state of fibrinogen. Thromb Haemost. 1990 Aug 13; 64(1):41-6. Zamarron C, Ginsberg MH, Plow EF. PMID: 1703332.
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    322. A unique recognition site mediates the interaction of fibrinogen with the leukocyte integrin Mac-1 (CD11b/CD18). J Biol Chem. 1990 Jul 25; 265(21):12119-22. Altieri DC, Agbanyo FR, Plescia J, Ginsberg MH, Edgington TS, Plow EF. PMID: 1973686.
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    323. Human endothelial cells synthesize, process, and secrete fibronectin molecules bearing an alternatively spliced type III homology (ED1). Blood. 1990 May 01; 75(9):1801-8. Peters JH, Sporn LA, Ginsberg MH, Wagner DD. PMID: 2331521.
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    324. Selective inhibition of integrin function by antibodies specific for ligand-occupied receptor conformers. J Biol Chem. 1990 Apr 15; 265(11):6346-52. Frelinger AL, Cohen I, Plow EF, Smith MA, Roberts J, Lam SC, Ginsberg MH. PMID: 2318856.
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    325. The ligand binding site of the platelet integrin receptor GPIIb-IIIa is proximal to the second calcium binding domain of its alpha subunit. J Biol Chem. 1990 Feb 25; 265(6):3440-6. D'Souza SE, Ginsberg MH, Burke TA, Plow EF. PMID: 2303453.
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    326. Efficient surface expression of platelet GPIIb-IIIa requires both subunits. Blood. 1989 Jul; 74(1):14-8. O'Toole TE, Loftus JC, Plow EF, Glass AA, Harper JR, Ginsberg MH. PMID: 2752106.
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    327. Immunoblot analysis of platelet glycoprotein IIb in patients with Glanzmann thrombasthenia in Israel. Br J Haematol. 1989 Jul; 72(3):415-23. Seligsohn U, Coller BS, Zivelin A, Plow EF, Ginsberg MH. PMID: 2765408.
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    328. Amino acid sequences in fibrinogen mediating its interaction with its platelet receptor, GPIIbIIIa. J Biol Chem. 1989 Jun 05; 264(16):9258-65. Andrieux A, Hudry-Clergeon G, Ryckewaert JJ, Chapel A, Ginsberg MH, Plow EF, Marguerie G. PMID: 2722830.
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    329. Differential structural requirements for fibrinogen binding to platelets and to endothelial cells. J Cell Biol. 1989 Jun; 108(6):2519-27. Tranqui L, Andrieux A, Hudry-Clergeon G, Ryckewaert JJ, Soyez S, Chapel A, Ginsberg MH, Plow EF, Marguerie G. PMID: 2738096; PMCID: PMC2115601.
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    330. Platelet membrane glycoprotein IIb heavy chain forms a complex with glycoprotein IIIa that binds Arg-Gly-Asp peptides. Blood. 1989 May 01; 73(6):1513-8. Lam SC, Plow EF, Ginsberg MH. PMID: 2713490.
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    331. Elevated plasma levels of ED1+ ("cellular") fibronectin in patients with vascular injury. J Lab Clin Med. 1989 May; 113(5):586-97. Peters JH, Maunder RJ, Woolf AD, Cochrane CG, Ginsberg MH. PMID: 2715681.
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    332. Isolation and characterization of a platelet membrane protein related to the vitronectin receptor. J Biol Chem. 1989 Mar 05; 264(7):3742-9. Lam SC, Plow EF, D'Souza SE, Cheresh DA, Frelinger AL, Ginsberg MH. PMID: 2465293.
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    333. Fibrinogen-endothelial cell interaction in vitro: a pathway mediated by an Arg-Gly-Asp recognition specificity. Blood. 1989 Feb 15; 73(3):734-42. Languino LR, Colella S, Zanetti A, Andrieux A, Ryckewaert JJ, Charon MH, Marchisio PC, Plow EF, Ginsberg MH, Marguerie G, et al. PMID: 2537118.
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    334. Cellular adhesion: GPIIb-IIIa as a prototypic adhesion receptor. Prog Hemost Thromb. 1989; 9:117-56. Plow EF, Ginsberg MH. PMID: 2643815.
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    336. Localization of an Arg-Gly-Asp recognition site within an integrin adhesion receptor. Science. 1988 Oct 07; 242(4875):91-3. D'Souza SE, Ginsberg MH, Burke TA, Lam SC, Plow EF. PMID: 3262922.
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    337. Occupancy of an adhesive glycoprotein receptor modulates expression of an antigenic site involved in cell adhesion. J Biol Chem. 1988 Sep 05; 263(25):12397-402. Frelinger AL, Lam SC, Plow EF, Smith MA, Loftus JC, Ginsberg MH. PMID: 2457583.
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    338. Alternative proteolytic processing of platelet membrane glycoprotein IIb. J Biol Chem. 1988 Aug 15; 263(23):11025-8. Loftus JC, Plow EF, Jennings LK, Ginsberg MH. PMID: 2457017.
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    339. The inflammatory reaction to crystals. Rheum Dis Clin North Am. 1988 Aug; 14(2):353-64. Terkeltaub RA, Ginsberg MH. PMID: 3051154.
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    340. Release of soluble fibronectin containing an extra type III domain (ED1) during acute pulmonary injury mediated by oxidants or leukocytes in vivo. Am Rev Respir Dis. 1988 Jul; 138(1):167-74. Peters JH, Ginsberg MH, Case CM, Cochrane CG. PMID: 3202394.
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    341. Chemical cross-linking of arginyl-glycyl-aspartic acid peptides to an adhesion receptor on platelets. J Biol Chem. 1988 Mar 15; 263(8):3943-51. D'Souza SE, Ginsberg MH, Lam SC, Plow EF. PMID: 3346230.
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    342. The localization of a platelet GpIIb-IIIa-related protein in endothelial cell adhesion structures. Blood. 1988 Mar; 71(3):566-72. Dejana E, Languino LR, Colella S, Corbascio GC, Plow E, Ginsberg M, Marchisio PC. PMID: 3345337.
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    343. Cytoadhesins, integrins, and platelets. Thromb Haemost. 1988 Feb 25; 59(1):1-6. Ginsberg MH, Loftus JC, Plow EF. PMID: 3283991.
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    351. Immunochemical and amino-terminal sequence comparison of two cytoadhesins indicates they contain similar or identical beta subunits and distinct alpha subunits. J Biol Chem. 1987 Apr 25; 262(12):5437-40. Ginsberg MH, Loftus J, Ryckwaert JJ, Pierschbacher M, Pytela R, Ruoslahti E, Plow EF. PMID: 2437107.
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    353. Divalent cation-dependent and independent surface expression of thrombospondin on thrombin-stimulated human platelets. Blood. 1987 Jan; 69(1):58-64. Aiken ML, Ginsberg MH, Plow EF. PMID: 3024762.
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    354. Intravascular release of intact cellular fibronectin during oxidant-induced injury of the in vitro perfused rabbit lung. J Clin Invest. 1986 Dec; 78(6):1596-603. Peters JH, Ginsberg MH, Bohl BP, Sklar LA, Cochrane CG. PMID: 3023447; PMCID: PMC423927.
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    355. Identification of a new class of inducible receptors on platelets. Thrombospondin interacts with platelets via a GPIIb-IIIa-independent mechanism. J Clin Invest. 1986 Dec; 78(6):1713-6. Aiken ML, Ginsberg MH, Plow EF. PMID: 3782477; PMCID: PMC423947.
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    356. Apolipoprotein B mediates the capacity of low density lipoprotein to suppress neutrophil stimulation by particulates. J Biol Chem. 1986 Nov 25; 261(33):15662-7. Terkeltaub R, Martin J, Curtiss LK, Ginsberg MH. PMID: 3096995.
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    357. Divalent cation regulation of the surface orientation of platelet membrane glycoprotein IIb. Correlation with fibrinogen binding function and definition of a novel variant of Glanzmann's thrombasthenia. J Clin Invest. 1986 Oct; 78(4):1103-11. Ginsberg MH, Lightsey A, Kunicki TJ, Kaufmann A, Marguerie G, Plow EF. PMID: 2428841; PMCID: PMC423772.
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    358. Expression of intracellular fibrinogen on the surface of stimulated platelets. Eur J Biochem. 1986 Aug 15; 159(1):61-7. Courtois G, Ryckewaert JJ, Woods VL, Ginsberg MH, Plow EF, Marguerie GA. PMID: 3743572.
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    359. Immunologic relationship between platelet membrane glycoprotein GPIIb/IIIa and cell surface molecules expressed by a variety of cells. Proc Natl Acad Sci U S A. 1986 Aug; 83(16):6002-6. Plow EF, Loftus JC, Levin EG, Fair DS, Dixon D, Forsyth J, Ginsberg MH. PMID: 2426709; PMCID: PMC386425.
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    360. Localization of internal pools of membrane glycoproteins involved in platelet adhesive responses. Am J Pathol. 1986 Aug; 124(2):324-34. Wencel-Drake JD, Plow EF, Kunicki TJ, Woods VL, Keller DM, Ginsberg MH. PMID: 2943164; PMCID: PMC1888283.
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    361. A platelet alpha granule membrane protein that is associated with the plasma membrane after activation. Characterization and subcellular localization of platelet activation-dependent granule-external membrane protein. J Clin Invest. 1986 Jul; 78(1):130-7. Berman CL, Yeo EL, Wencel-Drake JD, Furie BC, Ginsberg MH, Furie B. PMID: 2941452; PMCID: PMC329541.
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    362. Ultrastructural localization of coagulation factor V in human platelets. Blood. 1986 Jul; 68(1):244-9. Wencel-Drake JD, Dahlback B, White JG, Ginsberg MH. PMID: 3521762.
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    363. Plasminogen interacts with human platelets through two distinct mechanisms. J Clin Invest. 1986 Jun; 77(6):2001-9. Miles LA, Ginsberg MH, White JG, Plow EF. PMID: 3086385; PMCID: PMC370561.
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    364. Interaction of thrombospondin with resting and stimulated human platelets. J Biol Chem. 1986 May 25; 261(15):6840-6. Wolff R, Plow EF, Ginsberg MH. PMID: 3084490.
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    365. Platelet membrane glycoprotein IIb/IIIa: member of a family of Arg-Gly-Asp--specific adhesion receptors. Science. 1986 Mar 28; 231(4745):1559-62. Pytela R, Pierschbacher MD, Ginsberg MH, Plow EF, Ruoslahti E. PMID: 2420006.
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    366. Low density lipoprotein inhibits the physical interaction of phlogistic crystals and inflammatory cells. Arthritis Rheum. 1986 Mar; 29(3):363-70. Terkeltaub R, Smeltzer D, Curtiss LK, Ginsberg MH. PMID: 3964313.
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    367. The effect of Arg-Gly-Asp-containing peptides on fibrinogen and von Willebrand factor binding to platelets. Proc Natl Acad Sci U S A. 1985 Dec; 82(23):8057-61. Plow EF, Pierschbacher MD, Ruoslahti E, Marguerie GA, Ginsberg MH. PMID: 3877935; PMCID: PMC391441.
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    368. Related binding mechanisms for fibrinogen, fibronectin, von Willebrand factor, and thrombospondin on thrombin-stimulated human platelets. Blood. 1985 Sep; 66(3):724-7. Plow EF, McEver RP, Coller BS, Woods VL, Marguerie GA, Ginsberg MH. PMID: 3875376.
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    369. Fibronectin binding to thrombin-stimulated platelets: evidence for fibrin(ogen) independent and dependent pathways. Blood. 1985 Jul; 66(1):26-32. Plow EF, Marguerie GA, Ginsberg MH. PMID: 4005431.
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    370. Inhibition of fibronectin binding to platelets by proteolytic fragments and synthetic peptides which support fibroblast adhesion. J Biol Chem. 1985 Apr 10; 260(7):3931-6. Ginsberg M, Pierschbacher MD, Ruoslahti E, Marguerie G, Plow E. PMID: 3980461.
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    371. Ultrastructural localization of human platelet thrombospondin, fibrinogen, fibronectin, and von Willebrand factor in frozen thin section. Blood. 1985 Apr; 65(4):929-38. Wencel-Drake JD, Painter RG, Zimmerman TS, Ginsberg MH. PMID: 2579691.
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    372. Direct evidence for the interaction of platelet surface membrane proteins GPIIb and III with cytoskeletal components: protein crosslinking studies. J Cell Biochem. 1985; 27(3):277-90. Painter RG, Gaarde W, Ginsberg MH. PMID: 3157694.
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    373. Fibrinogen and platelet function. Adv Exp Med Biol. 1985; 192:41-54. Marguerie GA, Ginsberg MH, Plow EF. PMID: 3010672.
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    374. Platelet-collagen adhesion: inhibition by a monoclonal antibody that binds glycoprotein IIb. J Cell Biol. 1984 Dec; 99(6):2056-60. Shadle PJ, Ginsberg MH, Plow EF, Barondes SH. PMID: 6238974; PMCID: PMC2113561.
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    375. Centripetal myosin redistribution in thrombin-stimulated platelets. Relationship to platelet Factor 4 secretion. Exp Cell Res. 1984 Nov; 155(1):198-212. Painter RG, Ginsberg MH. PMID: 6386495.
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    376. Detection and partial characterization of an inhibitor of plasminogen activator in human platelets. J Clin Invest. 1984 Oct; 74(4):1465-72. Erickson LA, Ginsberg MH, Loskutoff DJ. PMID: 6434594; PMCID: PMC425316.
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    377. Lipoproteins containing apoprotein B are a major regulator of neutrophil responses to monosodium urate crystals. J Clin Invest. 1984 Jun; 73(6):1719-30. Terkeltaub R, Curtiss LK, Tenner AJ, Ginsberg MH. PMID: 6725556; PMCID: PMC437084.
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    378. Evidence that three adhesive proteins interact with a common recognition site on activated platelets. J Biol Chem. 1984 May 10; 259(9):5388-91. Plow EF, Srouji AH, Meyer D, Marguerie G, Ginsberg MH. PMID: 6325435.
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    379. Immunofluorescent localization of adhesive glycoproteins in resting and thrombin-stimulated platelets. Am J Pathol. 1984 May; 115(2):156-64. Wencel-Drake JD, Plow EF, Zimmerman TS, Painter RG, Ginsberg MH. PMID: 6232852; PMCID: PMC1900488.
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    380. The platelet-fibrinogen interaction. Evidence for proximity of the A alpha chain of fibrinogen to platelet membrane glycoproteins IIb/III. Eur J Biochem. 1984 Feb 15; 139(1):5-11. Marguerie GA, Thomas-Maison N, Ginsberg MH, Plow EF. PMID: 6230229.
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    381. Molecular mechanisms of gouty arthritis: new insights into an old disease. Surv Synth Pathol Res. 1984; 3(5):386-96. Terkeltaub R, Ginsberg MH. PMID: 6395263.
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    382. Binding of fibronectin to alpha-granule-deficient platelets. J Cell Biol. 1983 Aug; 97(2):571-3. Ginsberg MH, Wencel JD, White JG, Plow EF. PMID: 6309863; PMCID: PMC2112534.
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    383. Plasma protein binding by monosodium urate crystals. Analysis by two-dimensional gel electrophoresis. Arthritis Rheum. 1983 Jun; 26(6):775-83. Terkeltaub R, Tenner AJ, Kozin F, Ginsberg MH. PMID: 6305372.
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    384. Reduced surface expression and binding of fibronectin by thrombin-stimulated thrombasthenic platelets. J Clin Invest. 1983 Mar; 71(3):619-24. Ginsberg MH, Forsyth J, Lightsey A, Chediak J, Plow EF. PMID: 6826726; PMCID: PMC436911.
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    385. New synthesis of a platelet-specific protein: platelet factor 4 synthesis in a megakaryocyte-enriched rabbit bone marrow culture system. J Cell Biol. 1983 Feb; 96(2):515-20. Ryo R, Nakeff A, Huang SS, Ginsberg M, Deuel TF. PMID: 6833369; PMCID: PMC2112287.
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    386. [Multimeric structure of factor VIII/von Willebrand factor released from human platelets by ADP, collagen and thrombin]. Sangre (Barc). 1983; 28(4):439-49. López Fernández MF, Batlle Fonrodona FJ, Ginsberg MH, Ruggeri ZM, Zimmerman TS. PMID: 6419355.
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    387. Multimeric structure of platelet factor VIII/von Willebrand factor: the presence of larger multimers and their reassociation with thrombin-stimulated platelets. Blood. 1982 Nov; 60(5):1132-8. Fernandez MF, Ginsberg MH, Ruggeri ZM, Batlle FJ, Zimmerman TS. PMID: 6982084.
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    388. The role of cell surface proteins in platelet stimulation by monosodium urate crystals. Arthritis Rheum. 1982 May; 25(5):508-21. Jaques BC, Ginsberg MH. PMID: 7082398.
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    389. Concanavalin A induces interactions between surface glycoproteins and the platelet cytoskeleton. J Cell Biol. 1982 Feb; 92(2):565-73. Painter RG, Ginsberg M. PMID: 6460776; PMCID: PMC2112059.
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    390. Specific and saturable binding of plasma fibronectin to thrombin-stimulated human platelets. J Biol Chem. 1981 Sep 25; 256(18):9477-82. Plow EF, Ginsberg MH. PMID: 6270087.
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    391. Fibronectin expression on the platelet surface occurs in concert with secretion. J Supramol Struct Cell Biochem. 1981; 17(1):91-8. Ginsberg MH, Plow EF, Forsyth J. PMID: 7198692.
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    392. The mechanism of thrombin-induced platelet factor 4 secretion. Blood. 1980 Apr; 55(4):661-8. Ginsberg MH, Taylor L, Painter RG. PMID: 6986924.
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    393. Urate crystal--dependent cleavage of Hageman factor in human plasma and synovial fluid. J Lab Clin Med. 1980 Apr; 95(4):497-506. Ginsberg MH, Jaques B, Cochrane CG, Griffin JH. PMID: 6898641.
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    394. Thrombin increases expression of fibronectin antigen on the platelet surface. Proc Natl Acad Sci U S A. 1980 Feb; 77(2):1049-53. Ginsberg MH, Painter RG, Forsyth J, Birdwell C, Plow EF. PMID: 6987662; PMCID: PMC348421.
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    395. Polymorphonuclear leukocyte responses to monosodium urate crystals: modification by adsorbed serum proteins. J Rheumatol. 1979 Sep-Oct; 6(5):519-26. Kozin F, Ginsberg MH, Skosey JL. PMID: 522099.
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    396. Immunoglobulin G independent activation of the classical complement pathway by monosodium urate crystals. J Clin Invest. 1979 Apr; 63(4):759-64. Giclas PC, Ginsberg MH, Cooper NR. PMID: 438335; PMCID: PMC372012.
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    397. Mechanisms of platelet response to monosodium urate crystals. Am J Pathol. 1979 Mar; 94(3):549-68. Ginsberg M, Henson P, Henson J, Kozin F. PMID: 426039; PMCID: PMC2042258.
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    398. Identification and quantitation of platelet-associated fibronectin antigen. J Clin Invest. 1979 Mar; 63(3):540-3. Plow EF, Birdwell C, Ginsberg MH. PMID: 372243; PMCID: PMC371985.
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    399. Mechanisms of cellular interaction with monosodium urate crystals. IgG-dependent and IgG-independent platelet stimulation by urate crystals. Arthritis Rheum. 1978 Nov-Dec; 21(8):896-903. Ginsberg MH, Kozin F. PMID: 737013.
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    400. The selective binding of aggregated IgG to lipid A-rich bacterial lipopolysaccharides. J Immunol. 1978 Jan; 120(1):317-9. Ginsberg MH, Morrison DC. PMID: 627721.
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    401. Enhancement of platelet response to immune complexes and IgG aggregates by lipid A-rich bacterial lipopolysaccharides. J Exp Med. 1978 Jan 01; 147(1):207-17. Ginsberg MH, Henson PM. PMID: 627836; PMCID: PMC2184097.
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    402. Release of platelet constituents by monosodium urate crystals. J Clin Invest. 1977 Nov; 60(5):999-1007. Ginsberg MH, Kozin F, O'Malley M, McCarty DJ. PMID: 908764; PMCID: PMC372451.
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    403. Adsorption of polymorphonuclear leukocyte lysosomal enzymes to monosodium urate crystals. Arthritis Rheum. 1977 Nov-Dec; 20(8):1538-42. Ginsberg MH, Kozin F, Chow D, May J, Skosey JL. PMID: 921826.
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    404. Serum factors releasing serotonin from normal platelets: relation to the manifestations of systemic lupus erythematosus. Ann Intern Med. 1977 Nov; 87(5):564-7. Ginsberg MH, O'Malley M. PMID: 921084.
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    405. Protein adsorption to monosodium urate crystals: differential responses of human peripheral blood neutrophils. Adv Exp Med Biol. 1977; 76B:209-13. Skosey JL, Kozin F, Ginsberg M. PMID: 855747.
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    406. Protein binding to monosodium urate crystals and its effect on platelet degranulation. Adv Exp Med Biol. 1977; 768:201-8. Kozin F, Ginsberg M, Karasek V, Skosey J, McCarty D. PMID: 855768.
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    407. Porphyrin synthesis by cultured lymphocytes. Blood. 1972 Apr; 39(4):568-74. Josephson AS, Levere RD, Lowenthal I, Swerdlow F, Ginsberg M. PMID: 5011979.
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