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Shizhen Emily Wang

Title(s)Professor, Pathology
SchoolHealth Sciences
Address9500 Gilman Drive #0612
La Jolla CA 92093
Phone858-246-2464
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    Collapse Education and Training
    Nankai UniversityPh.D.Virology
    University of Nebraska, LincolnPh.D. (joint)Virology
    Johns Hopkins Universitypost-docViral Oncology
    Vanderbilt Universitypost-docCancer Biology

    Collapse Overview 
    Collapse Overview
    Our group has a long-standing interest in understanding the multifaceted interactions between tumor and host at the Molecular, Cellular, and Organ levels. We currently focus on mechanisms mediated by cancer-secreted extracellular vesicles and their microRNA and protein cargo, for their role in systemic manifestations and comorbidities of breast cancer such as metabolic diseases, cachexia, and neurological disorders.

    Collapse Research 
    Collapse Research Activities and Funding
    Targeting Chemotherapy-induced Breast Cancer Stemness
    NIH/NCI R01CA206911Aug 1, 2017 - Jul 31, 2022
    Role: Principal Investigator
    Role of breast cancer-secreted miRNA in directing a stromal metabolic plasticity
    NIH/NCI R01CA218140Aug 1, 2017 - Jul 31, 2022
    Role: Principal Investigator
    Role of miR-105 in breast cancer metastasis
    NIH/NCI R01CA166020Sep 1, 2012 - Jun 30, 2017
    Role: Principal Investigator
    Mechanism of chemoresistance mediated by TGF-beta
    NIH/NCI R01CA163586May 1, 2012 - Mar 31, 2017
    Role: Principal Investigator
    Crosstalk TGFbeta and HER2 (ErbB2) Signaling in Mammary Tumorigenesis
    NIH/NCI R00CA125892Jul 25, 2007 - Jun 30, 2012
    Role: Principal Investigator
    Crosstalk TGFbeta and HER2 (ErbB2) Signaling in Mammary Tumorigenesis
    NIH/NCI K99CA125892Jul 25, 2007 - Jun 30, 2009
    Role: Principal Investigator

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