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    Edward Holmes

    TitleEmeritus Professor
    SchoolUniversity of California, San Diego
    DepartmentMedicine
    Address9500 Gilman Drive #0602
    CA La Jolla 92093
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      Collapse Research 
      Collapse Research Activities and Funding
      Cond. Acceptance Post-Bac. Prog. Scholarship Fund
      NIH/NIMHD S22MD000227Sep 30, 2002 - Sep 29, 2005
      Role: Co-Principal Investigator
      San Diego Regional IRB Enhancements
      NIH/NCRR S07RR018186Sep 1, 2002 - Aug 31, 2005
      Role: Principal Investigator
      RETROVIRAL ANTI-SENSE RNA--CELLULAR AND VIRAL RESPONSES
      NIH/NCI R01CA047631Jul 1, 1988 - Jun 30, 1993
      Role: Principal Investigator
      PHENOTYPE OF METABOLIC DISEASE CREATED BY VECTORS
      NIH/NIDDK R03DK039715Sep 1, 1987 - Aug 31, 1988
      Role: Principal Investigator
      ROLE OF THE DIENCEPHALON IN MEMORY
      NIH/NINDS R23NS020844Sep 1, 1983 - Aug 31, 1986
      Role: Principal Investigator
      PATHOBIOLOGY OF AMP DEAMINASE DEFICIENCY
      NIH/NIDDK R01DK012413May 1, 1979 - Apr 30, 2001
      Role: Principal Investigator
      PATHOGENISIS OF AMP DEAMINASE DEFICIENCY
      NIH/NIDDK R37DK012413May 1, 1979 - Apr 30, 1997
      Role: Principal Investigator
      PURINE METABOLISM:NUCLEOTIDE SYNTHESIS &INTERCONVERSION
      NIH/NIADDK R01AM012413May 1, 1979 - Apr 30, 1989
      Role: Principal Investigator
      GENERAL CLINICAL RESEARCH CENTER
      NIH/NCRR M01RR000030Oct 1, 1975 - Mar 31, 2009
      Role: Co-Principal Investigator
      METABOLIC AND RHEUMATIC DISEASES
      NIH/NIADDK T32AM007015Jul 1, 1975 - Jun 30, 1986
      Role: Principal Investigator
      General Clinical Research Center
      NIH/NCRR M01RR000827Mar 1, 1974 - Nov 30, 2010
      Role: Co-Principal Investigator

      Collapse Bibliographic 
      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Cheng J, Morisaki H, Toyama K, Sugimoto N, Shintani T, Tandelilin A, Hirase T, Holmes E, Morisaki T. AMPD1: a novel therapeutic target for reversing insulin resistance. BMC Endocr Disord. 2014; 14:96. PMID: 25511531.
        View in: PubMed
      2. Cheng J, Morisaki H, Sugimoto N, Dohi A, Shintani T, Kimura E, Toyama K, Ikawa M, Okabe M, Higuchi I, Matsuo S, Kawai Y, Hisatome I, Sugama T, Holmes E, Morisaki T. Effect of isolated AMP deaminase deficiency on skeletal muscle function. Mol Genet Metab Rep. 2014; 1:51-59. PMID: 27896074.
        View in: PubMed
      3. Akizu N, Cantagrel V, Schroth J, Cai N, Vaux K, McCloskey D, Naviaux RK, Van Vleet J, Fenstermaker AG, Silhavy JL, Scheliga JS, Toyama K, Morisaki H, Sonmez FM, Celep F, Oraby A, Zaki MS, Al-Baradie R, Faqeih EA, Saleh MA, Spencer E, Rosti RO, Scott E, Nickerson E, Gabriel S, Morisaki T, Holmes E, Gleeson JG. AMPD2 regulates GTP synthesis and is mutated in a potentially treatable neurodegenerative brainstem disorder. Cell. 2013 Aug 1; 154(3):505-17. PMID: 23911318.
        View in: PubMed
      4. Brady LS, Giffin RB, Woodcock J, Cassell GH, Holmes E. Grand challenges for psychiatric drug discovery: a perspective. Neuropsychopharmacology. 2008 Aug; 33(9):2047. PMID: 18626470.
        View in: PubMed
      5. Holmes E. Of rice and men: Bill Kelley's next generation. J Clin Invest. 2005 Oct; 115(10):2948-52. PMID: 16200216.
        View in: PubMed
      6. Goodarzi MO, Taylor KD, Guo X, QuiƱones MJ, Cui J, Li X, Hang T, Yang H, Holmes E, Hsueh WA, Olefsky J, Rotter JI. Variation in the gene for muscle-specific AMP deaminase is associated with insulin clearance, a highly heritable trait. Diabetes. 2005 Apr; 54(4):1222-7. PMID: 15793265.
        View in: PubMed
      7. Lavori PW, Krause-Steinrauf H, Brophy M, Buxbaum J, Cockroft J, Cox DR, Fiore L, Greely HT, Greenberg H, Holmes E, Nelson LM, Sugarman J. Principles, organization, and operation of a DNA bank for clinical trials: a Department of Veterans Affairs cooperative study. Control Clin Trials. 2002 Jun; 23(3):222-39. PMID: 12057876.
        View in: PubMed
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