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Multi-molecular hyperspectral PRM-SRS microscopy. Nat Commun. 2024 Feb 21; 15(1):1599.
Zhang W, Li Y, Fung AA, Li Z, Jang H, Zha H, Chen X, Gao F, Wu JY, Sheng H, Yao J, Skowronska-Krawczyk D, Jain S, Shi L. PMID: 38383552; PMCID: PMC10881988.
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PubMed Mentions:
1 Fields:
Translation:
HumansAnimals
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Far-red chemigenetic biosensors for multi-dimensional and super-resolved kinase activity imaging. bioRxiv. 2024 Feb 11.
Frei MS, Sanchez SA, Liu L, Schneider F, Wang Z, Hakozaki H, Li Y, Lyons AC, Rohm TV, Olefsky JM, Shi L, Schöneberg J, Fraser SE, Mehta S, Wang Y, Zhang J. PMID: 38370804; PMCID: PMC10871310.
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PubMed Mentions:
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Super-Resolution Stimulated Raman Scattering Microscopy with Graphical User Interface-Supported A-PoD. Curr Protoc. 2024 Jan; 4(1):e970.
Jang H, Li Y, Wu S, Shi L. PMID: 38270527; PMCID: PMC10832363.
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PubMed Mentions: Fields:
-
Femtosecond optical Kerr effect in normal and grades of cancerous breast tissues as a new optical biopsy method. J Biophotonics. 2024 Feb; 17(2):e202300344.
Meyer HJ, Mamani S, Li Z, Shi L, Alfano RR. PMID: 38010367.
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PubMed Mentions: Fields:
Translation:
HumansAnimals
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Self-Assembled Homopolymeric Spherulites from Small Molecules in Solution. J Am Chem Soc. 2023 11 29; 145(47):25664-25672.
Song Q, Li Y, Jin Z, Liu H, Creyer MN, Yim W, Huang Y, Hu X, He T, Li Y, Kelley SO, Shi L, Zhou J, Jokerst JV. PMID: 37921495.
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PubMed Mentions: Fields:
Translation:
Cells
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Multimodal imaging of metabolic activities for distinguishing subtypes of breast cancer. Biomed Opt Express. 2023 Nov 01; 14(11):5764-5780.
Li Z, Nguyen C, Jang H, Hoang D, Min S, Ackerstaff E, Koutcher JA, Shi L. PMID: 38021123; PMCID: PMC10659775.
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PubMed Mentions:
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Early cancer detection by SERS spectroscopy and machine learning. Light Sci Appl. 2023 Sep 15; 12(1):234.
Shi L, Li Y, Li Z. PMID: 37714845; PMCID: PMC10504315.
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PubMed Mentions:
6
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Goldilocks Energy Minimum: Peptide-Based Reversible Aggregation and Biosensing. ACS Appl Mater Interfaces. 2023 Sep 13; 15(36):42293-42303.
Yim W, Retout M, Chen AA, Ling C, Amer L, Jin Z, Chang YC, Chavez S, Barrios K, Lam B, Li Z, Zhou J, Shi L, Pascal TA, Jokerst JV. PMID: 37651748; PMCID: PMC10619458.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Perspectives on SRS Imaging of Nanoparticles. Acc Mater Res. 2023 Sep 22; 4(9):726-728.
Shi L, Jang H. PMID: 37766942; PMCID: PMC10521017.
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PubMed Mentions:
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Bioorthogonal Stimulated Raman Scattering Imaging Uncovers Lipid Metabolic Dynamics in Drosophila Brain During Aging. GEN Biotechnol. 2023 Jun 01; 2(3):247-261.
Li Y, Chang P, Sankaran S, Jang H, Nie Y, Zeng A, Hussain S, Wu JY, Chen X, Shi L. PMID: 37363411; PMCID: PMC10286263.
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PubMed Mentions:
3
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Bioorthogonal Chemical Imaging of Cell Metabolism Regulated by Aromatic Amino Acids. J Vis Exp. 2023 05 12; (195).
Bagheri P, Hoang K, Kuo CY, Trivedi H, Jang H, Shi L. PMID: 37246865; PMCID: PMC10725321.
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PubMed Mentions:
2 Fields:
Translation:
HumansCells
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Femtosecond Optical Kerr Gates in Cancerous Breast Tissue for a New Optical Biopsy Method. Res Sq. 2023 May 10.
Meyer H, Mamani S, Li Z, Shi L, Alfano R. PMID: 37214848; PMCID: PMC10197745.
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PubMed Mentions:
-
View in:
PubMed Mentions:
8 Fields:
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Alzheimer's-Associated Upregulation of Mitochondria-Associated ER Membranes After Traumatic Brain Injury. Cell Mol Neurobiol. 2023 Jul; 43(5):2219-2241.
Agrawal RR, Larrea D, Xu Y, Shi L, Zirpoli H, Cummins LG, Emmanuele V, Song D, Yun TD, Macaluso FP, Min W, Kernie SG, Deckelbaum RJ, Area-Gomez E. PMID: 36571634; PMCID: PMC10287820.
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PubMed Mentions:
4 Fields:
Translation:
AnimalsCells
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Towards Mapping Mouse Metabolic Tissue Atlas by Mid-Infrared Imaging with Heavy Water Labeling. Adv Sci (Weinh). 2022 05; 9(15):e2105437.
Liu X, Shi L, Shi L, Wei M, Zhao Z, Min W. PMID: 35319171; PMCID: PMC9131428.
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PubMed Mentions:
5 Fields:
Translation:
Animals
-
Imaging Sub-Cellular Methionine and Insulin Interplay in Triple Negative Breast Cancer Lipid Droplet Metabolism. Front Oncol. 2022; 12:858017.
Fung AA, Hoang K, Zha H, Chen D, Zhang W, Shi L. PMID: 35359364; PMCID: PMC8960266.
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PubMed Mentions:
7
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DO-SRS imaging of diet regulated metabolic activities in Drosophila during aging processes. Aging Cell. 2022; (e13586).
Yajuan Li, Wenxu Zhang, Anthony A. Fung, Lingyan Shi. . View Publication.
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DO-SRS imaging of diet regulated metabolic activities in Drosophila during aging processes. Aging Cell. 2022 04; 21(4):e13586.
Li Y, Zhang W, Fung AA, Shi L. PMID: 35257470; PMCID: PMC9009230.
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PubMed Mentions:
9 Fields:
Translation:
Animals
-
A high-throughput technique to map cell images to cell positions using a 3D imaging flow cytometer. Proc Natl Acad Sci U S A. 2022 02 22; 119(8).
Zhang Z, Tang R, Chen X, Waller L, Kau A, Fung AA, Gutierrez B, An C, Cho SH, Shi L, Lo YH. PMID: 35173045; PMCID: PMC8872737.
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PubMed Mentions:
3 Fields:
Translation:
Humans
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Direct Imaging of Lipid Metabolic Changes in Drosophila Ovary During Aging Using DO-SRS Microscopy. Front Aging. 2021; 2:819903.
Li Y, Bagheri P, Chang P, Zeng A, Hao J, Fung A, Wu JY, Shi L. PMID: 35822015; PMCID: PMC9261447.
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PubMed Mentions:
8
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Fano resonance line shapes in the Raman spectra of tubulin and microtubules reveal quantum effects. Biophys Rep (N Y). 2022 Mar 09; 2(1):100043.
Zhang W, Craddock TJA, Li Y, Swartzlander M, Alfano RR, Shi L. PMID: 36425084; PMCID: PMC9680776.
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PubMed Mentions:
2
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Visualizing Cancer Cell Metabolic Dynamics Regulated With Aromatic Amino Acids Using DO-SRS and 2PEF Microscopy. Front Mol Biosci. 2021; 8:779702.
Bagheri P, Hoang K, Fung AA, Hussain S, Shi L. PMID: 34977157; PMCID: PMC8714916.
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PubMed Mentions:
5
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DO-SRS imaging of metabolic dynamics in aging Drosophila. Analyst. 2021 Dec 06; 146(24):7510-7519.
Li Y, Zhang W, Fung AA, Shi L. PMID: 34781326; PMCID: PMC10870347.
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PubMed Mentions:
6 Fields:
Translation:
AnimalsCells
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Highly-multiplexed volumetric mapping with Raman dye imaging and tissue clearing. Nat Biotechnol. 2022 03; 40(3):364-373.
Shi L, Wei M, Miao Y, Qian N, Shi L, Singer RA, Benninger RKP, Min W. PMID: 34608326; PMCID: PMC8930416.
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PubMed Mentions:
22 Fields:
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Distinct Cellular Profiles of Hif1a and Vegf mRNA Localization in Microglia, Astrocytes and Neurons during a Period of Vascular Maturation in the Auditory Brainstem of Neonate Rats. Brain Sci. 2021 Jul 18; 11(7).
Chang D, Brown Q, Tsui G, He Y, Liu J, Shi L, Rodríguez-Contreras A. PMID: 34356178; PMCID: PMC8304335.
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PubMed Mentions:
3
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Advances in stimulated Raman scattering imaging for tissues and animals. Quant Imaging Med Surg. 2021 Mar; 11(3):1078-1101.
Shi L, Fung AA, Zhou A. PMID: 33654679; PMCID: PMC7829158.
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PubMed Mentions:
12
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Enhanced stimulated raman scattering of solvent due to anharmonic energy transfer from resonance raman solute molecules. Opt Express. 2020 Jul 20; 28(15):21792-21804.
Shi L, Gayen T, Budansky Y, Yoo K, Secor J, Harvey T, Harvey G, Shumyatsky P, Nolan D, Alfano R. PMID: 32752451; PMCID: PMC7470682.
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PubMed Mentions:
1 Fields:
-
Mammalian cell and tissue imaging using Raman and coherent Raman microscopy. Wiley Interdiscip Rev Syst Biol Med. 2020 11; 12(6):e1501.
Fung AA, Shi L. PMID: 32686297; PMCID: PMC7554227.
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PubMed Mentions:
11 Fields:
Translation:
HumansAnimals
-
Mid-infrared metabolic imaging with vibrational probes. Nat Methods. 2020 08; 17(8):844-851.
Shi L, Liu X, Shi L, Stinson HT, Rowlette J, Kahl LJ, Evans CR, Zheng C, Dietrich LEP, Min W. PMID: 32601425; PMCID: PMC7396315.
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PubMed Mentions:
39 Fields:
Translation:
Animals
-
Explanation of the competition between O- and E-wave induced stimulated Raman and supercontinuum in calcite under ultrafast laser excitation. Appl Opt. 2020 Jun 10; 59(17):5252-5257.
Mazhar SFB, Meyer HJ, Samuels T, Sharonov M, Shi L, Alfano RR. PMID: 32543546.
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PubMed Mentions:
1 Fields:
-
Background-free imaging of chemical bonds by a simple and robust frequency-modulated stimulated Raman scattering microscopy. Opt Express. 2020 May 11; 28(10):15663-15677.
Xiong H, Qian N, Zhao Z, Shi L, Miao Y, Min W. PMID: 32403589; PMCID: PMC7340375.
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PubMed Mentions:
7 Fields:
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Distinguishing metastatic triple-negative breast cancer from nonmetastatic breast cancer using second harmonic generation imaging and resonance Raman spectroscopy. J Biophotonics. 2020 07; 13(7):e202000005.
Bendau E, Smith J, Zhang L, Ackerstaff E, Kruchevsky N, Wu B, Koutcher JA, Alfano R, Shi L. PMID: 32219996; PMCID: PMC7433748.
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PubMed Mentions:
11 Fields:
Translation:
Humans
-
Comparison of continuous wave versus picosecond SRS and the resonance SRS effect. Appl Opt. 2020 Jan 20; 59(3):622-627.
Shumyatsky P, Shi L, Sordillo LA, Budansky Y, Alfano RR. PMID: 32225186.
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PubMed Mentions: Fields:
Translation:
Animals
-
Optical biopsy identification and grading of gliomas using label-free visible resonance Raman spectroscopy. J Biomed Opt. 2019 09; 24(9):1-12.
Zhou Y, Liu CH, Wu B, Yu X, Cheng G, Zhu K, Wang K, Zhang C, Zhao M, Zong R, Zhang L, Shi L, Alfano RR. PMID: 31512439; PMCID: PMC6997631.
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PubMed Mentions:
18 Fields:
Translation:
HumansCells
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Majorana vortex photons a form of entangled photons propagation through brain tissue. J Biophotonics. 2019 10; 12(10):e201900036.
Mamani S, Shi L, Nolan D, Alfano R. PMID: 31162813.
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PubMed Mentions:
3 Fields:
Translation:
Humans
-
Spectral tracing of deuterium for imaging glucose metabolism. Nat Biomed Eng. 2019 05; 3(5):402-413.
Zhang L, Shi L, Shen Y, Miao Y, Wei M, Qian N, Liu Y, Min W. PMID: 31036888; PMCID: PMC6599680.
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PubMed Mentions:
63 Fields:
Translation:
HumansAnimalsCells
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Volumetric chemical imaging by clearing-enhanced stimulated Raman scattering microscopy. Proc Natl Acad Sci U S A. 2019 04 02; 116(14):6608-6617.
Wei M, Shi L, Shen Y, Zhao Z, Guzman A, Kaufman LJ, Wei L, Min W. PMID: 30872474; PMCID: PMC6452712.
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PubMed Mentions:
39 Fields:
Translation:
HumansAnimalsCells
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Transmission of classically entangled beams through mouse brain tissue. J Biophotonics. 2018 12; 11(12):e201800096.
Mamani S, Shi L, Ahmed T, Karnik R, Rodríguez-Contreras A, Nolan D, Alfano R. PMID: 30027681.
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PubMed Mentions:
4 Fields:
Translation:
Animals
-
Optical imaging of metabolic dynamics in animals. Nat Commun. 2018 08 06; 9(1):2995.
Shi L, Zheng C, Shen Y, Chen Z, Silveira ES, Zhang L, Wei M, Liu C, de Sena-Tomas C, Targoff K, Min W. PMID: 30082908; PMCID: PMC6079036.
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PubMed Mentions:
84 Fields:
Translation:
HumansAnimalsCells
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Visualizing protein synthesis in mice with in vivo labeling of deuterated amino acids using vibrational imaging. APL Photonics. 2018; 3(9):092401-1-10.
Shi L, Shen Y, Min W. View Publication.
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Resonance Raman scattering of β-carotene solution excited by visible laser beams into second singlet state. J Photochem Photobiol B. 2018 Feb; 179:18-22.
Lu L, Shi L, Secor J, Alfano R. PMID: 29306722.
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PubMed Mentions:
7 Fields:
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Two-color vibrational imaging of glucose metabolism using stimulated Raman scattering. Chem Commun (Camb). 2018 Jan 07; 54(2):152-155.
Long R, Zhang L, Shi L, Shen Y, Hu F, Zeng C, Min W. PMID: 29218356; PMCID: PMC5764084.
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PubMed Mentions:
23 Fields:
Translation:
HumansAnimalsCells
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Metabolic activity induces membrane phase separation in endoplasmic reticulum. Proc Natl Acad Sci U S A. 2017 12 19; 114(51):13394-13399.
Shen Y, Zhao Z, Zhang L, Shi L, Shahriar S, Chan RB, Di Paolo G, Min W. PMID: 29196526; PMCID: PMC5754785.
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PubMed Mentions:
55 Fields:
Translation:
HumansAnimalsCells
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Propagation of Gaussian and Laguerre-Gaussian vortex beams through mouse brain tissue. J Biophotonics. 2017 Dec; 10(12):1756-1760.
Shi L, Lindwasser L, Wang W, Alfano R, Rodríguez-Contreras A. PMID: 28635151; PMCID: PMC5862546.
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PubMed Mentions:
4 Fields:
Translation:
Animals
-
Label-Free Fluorescence Spectroscopy for Detecting Key Biomolecules in Brain Tissue from a Mouse Model of Alzheimer's Disease. Sci Rep. 2017 06 01; 7(1):2599.
Shi L, Lu L, Harvey G, Harvey T, Rodríguez-Contreras A, Alfano RR. PMID: 28572632; PMCID: PMC5454017.
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PubMed Mentions:
8 Fields:
Translation:
HumansAnimals
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Alzheimer mouse brain tissue measured by time resolved fluorescence spectroscopy using single- and multi-photon excitation of label free native molecules. J Biophotonics. 2018 01; 11(1).
Das B, Shi L, Budansky Y, Rodriguez-Contreras A, Alfano R. PMID: 28464457; PMCID: PMC5668196.
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PubMed Mentions:
6 Fields:
Translation:
AnimalsCells
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Short wavelength infrared optical windows for evaluation of benign and malignant tissues. J Biomed Opt. 2017 04 01; 22(4):45002.
Sordillo DC, Sordillo LA, Sordillo PP, Shi L, Alfano RR. PMID: 28384701.
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PubMed Mentions:
21 Fields:
Translation:
HumansAnimals
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Photon Entanglement Through Brain Tissue. Sci Rep. 2016 12 20; 6:37714.
Shi L, Galvez EJ, Alfano RR. PMID: 27995952; PMCID: PMC5171785.
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PubMed Mentions:
3 Fields:
Translation:
Animals
-
Vulnerable atherosclerotic plaque detection by resonance Raman spectroscopy. J Biomed Opt. 2016 12 01; 21(12):127006.
Liu CH, Boydston-White S, Weisberg A, Wang W, Sordillo LA, Perotte A, Tomaselli VP, Sordillo PP, Pei Z, Shi L, Alfano RR. PMID: 27999865; PMCID: PMC5174785.
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PubMed Mentions:
6 Fields:
Translation:
Humans
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Deep transmission of Laguerre-Gaussian vortex beams through turbid scattering media. Opt Lett. 2016 May 01; 41(9):2069-72.
Wang WB, Gozali R, Shi L, Lindwasser L, Alfano RR. PMID: 27128076.
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PubMed Mentions:
7 Fields:
-
Terahertz spectroscopy of brain tissue from a mouse model of Alzheimer's disease. J Biomed Opt. 2016 Jan; 21(1):15014.
Shi L, Shumyatsky P, Rodríguez-Contreras A, Alfano R. PMID: 26818714; PMCID: PMC4728211.
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PubMed Mentions:
10 Fields:
Translation:
Animals
-
Transmission in near-infrared optical windows for deep brain imaging. J Biophotonics. 2016 Jan; 9(1-2):38-43.
Shi L, Sordillo LA, Rodríguez-Contreras A, Alfano R. PMID: 26556561; PMCID: PMC4827444.
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PubMed Mentions:
63 Fields:
Translation:
Animals
-
Gaussian beam in two-photon fluorescence imaging of rat brain microvessel. J Biomed Opt. 2014 Dec; 19(12):126006.
Shi L, Rodríguez-Contreras A, Alfano RR. PMID: 25490048; PMCID: PMC4260768.
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PubMed Mentions:
7 Fields:
Translation:
Animals
-
Quantification of transient increase of the blood-brain barrier permeability to macromolecules by optimized focused ultrasound combined with microbubbles. Int J Nanomedicine. 2014; 9:4437-48.
Shi L, Palacio-Mancheno P, Badami J, Shin DW, Zeng M, Cardoso L, Tu R, Fu BM. PMID: 25258533; PMCID: PMC4173757.
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PubMed Mentions:
14 Fields:
Translation:
Animals
-
Temporal effects of vascular endothelial growth factor and 3,5-cyclic monophosphate on blood-brain barrier solute permeability in vivo. J Neurosci Res. 2014 Dec; 92(12):1678-89.
Shi L, Zeng M, Fu BM. PMID: 25066133; PMCID: PMC4692382.
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PubMed Mentions:
10 Fields:
Translation:
Animals
-
Deep two-photon microscopic imaging through brain tissue using the second singlet state from fluorescent agent chlorophyll α in spinach leaf. J Biomed Opt. 2014 Jun; 19(6):066009.
Shi L, Rodríguez-Contreras A, Budansky Y, Pu Y, Nguyen TA, Alfano RR. PMID: 24967915; PMCID: PMC4071303.
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PubMed Mentions:
4 Fields:
Translation:
Animals
-
A method to make a craniotomy on the ventral skull of neonate rodents. J Vis Exp. 2014 May 22; (87).
Rodríguez-Contreras A, Shi L, Fu BM. PMID: 24894439; PMCID: PMC4122667.
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PubMed Mentions:
3 Fields:
Translation:
Animals
-
Quantification of blood-brain barrier solute permeability and brain transport by multiphoton microscopy. J Biomech Eng. 2014 Mar; 136(3):031005.
Shi L, Zeng M, Sun Y, Fu BM. PMID: 24193698.
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PubMed Mentions:
42 Fields:
Translation:
Animals
-
Time-resolved photoluminescence of Zn(OH)2 and its composites with graphite oxides. Opt Lett. 2013 Jul 01; 38(13):2227-9.
Islam SZ, Gayen T, Das BB, Shi L, Seredych M, Moussawi A, Bandosz TJ, Alfano R. PMID: 23811885.
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PubMed Mentions: Fields:
-
Structural and optical characterization of Zn(OH)2 and its composites with graphite oxides. Opt Lett. 2013 Mar 15; 38(6):962-4.
Islam SM, Gayen T, Moussawi A, Shi L, Seredych M, Bandosz TJ, Alfano R. PMID: 23503274.
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PubMed Mentions:
1 Fields: