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Debashis Sahoo

Title(s)Assistant Professor, Pediatrics
SchoolHealth Sciences
Address9500 Gilman Drive #0984
La Jolla CA 92093
Phone858-246-1803
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    Collapse Biography 
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    Stanford University, Stanford, CA USAPhD9/25/08Electrical Engineering

    Collapse Research 
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    Macrophage Polarization in Response to Infections and Inflammation
    NIH R01AI155696Sep 22, 2020 - Aug 31, 2025
    Role: Co-Principal Investigator
    Precision therapeutics of inflammatory bowel disease guided by Boolean logic
    NIH UG3TR003355Aug 28, 2020 - Jul 31, 2023
    Role: Principal Investigator
    Annotation of cell types in human colon tissue using Boolean analysis
    NIH R01GM138385Jun 1, 2020 - May 31, 2024
    Role: Principal Investigator
    Application of Boolean Networks to discover stem and progenitor cells
    NIH R00CA151673Jul 1, 2014 - Aug 31, 2018
    Role: Principal Investigator
    Application of Boolean Networks to discover stem and progenitor cells
    NIH K99CA151673Jul 1, 2011 - Jun 30, 2014
    Role: Principal Investigator

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    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Immunosuppression of Macrophages Underlies the Cardioprotective Effects of CST (Catestatin). Hypertension. 2021 May 05; 77(5):1670-1682. PMID: 33826401.
      View in: PubMed   Mentions:    Fields:    
    2. A long isoform of GIV/Girdin contains a PDZ binding module that regulates localization and G-protein binding. J Biol Chem. 2021 Mar 03; 100493. PMID: 33675748.
      View in: PubMed   Mentions:    Fields:    
    3. Boolean implication analysis unveils candidate universal relationships in microbiome data. BMC Bioinformatics. 2021 Feb 05; 22(1):49. Vo D, Singh SC, Safa S, Sahoo D. PMID: 33546590.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    4. E-cigarettes compromise the gut barrier and trigger inflammation. iScience. 2021 Feb 19; 24(2):102035. Sharma A, Lee J, Fonseca AG, Moshensky A, Kothari T, Sayed IM, Ibeawuchi SR, Pranadinata RF, Ear J, Sahoo D, Crotty-Alexander LE, Ghosh P, Das S. PMID: 33537654.
      View in: PubMed   Mentions:
    5. Haematopoietic stem cell-dependent Notch transcription is mediated by p53 through the Histone chaperone Supt16h. Nat Cell Biol. 2020 12; 22(12):1411-1422. Espanola SG, Song H, Ryu E, Saxena A, Kim ES, Manegold JE, Nasamran CA, Sahoo D, Oh CK, Bickers C, Shin U, Grainger S, Park YH, Pandolfo L, Kang MS, Kang S, Myung K, Cooper KL, Yelon D, Traver D, Lee Y. PMID: 33230303.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    6. The DNA Glycosylase NEIL2 Suppresses Fusobacterium-Infection-Induced Inflammation and DNA Damage in Colonic Epithelial Cells. Cells. 2020 08 28; 9(9). Sayed IM, Chakraborty A, Abd El-Hafeez AA, Sharma A, Sahan AZ, Huang WJM, Sahoo D, Ghosh P, Hazra TK, Das S. PMID: 32872214.
      View in: PubMed   Mentions:    Fields:    
    7. DDX5 promotes oncogene C3 and FABP1 expressions and drives intestinal inflammation and tumorigenesis. Life Sci Alliance. 2020 10; 3(10). Abbasi N, Long T, Li Y, Yee BA, Cho BS, Hernandez JE, Ma E, Patel PR, Sahoo D, Sayed IM, Varki N, Das S, Ghosh P, Yeo GW, Huang WJM. PMID: 32817263.
      View in: PubMed   Mentions:    Fields:    
    8. Helicobacter pylori infection downregulates the DNA glycosylase NEIL2, resulting in increased genome damage and inflammation in gastric epithelial cells. J Biol Chem. 2020 08 07; 295(32):11082-11098. Sayed IM, Sahan AZ, Venkova T, Chakraborty A, Mukhopadhyay D, Bimczok D, Beswick EJ, Reyes VE, Pinchuk I, Sahoo D, Ghosh P, Hazra TK, Das S. PMID: 32518160.
      View in: PubMed   Mentions: 2     Fields:    
    9. GIV/Girdin and Exo70 Collaboratively Regulate the Mammalian Polarized Exocytic Machinery. iScience. 2020 Jul 24; 23(7):101246. Rohena C, Rajapakse N, Lo IC, Novick P, Sahoo D, Ghosh P. PMID: 32590327.
      View in: PubMed   Mentions:
    10. GIV•Kindlin Interaction Is Required for Kindlin-Mediated Integrin Recognition and Activation. iScience. 2020 Jun 26; 23(6):101209. Rohena C, Kalogriopoulos N, Rajapakse N, Roy S, Lopez-Sanchez I, Ablack J, Sahoo D, Ghosh P. PMID: 32535026.
      View in: PubMed   Mentions:
    11. Transcriptional profiling of lung macrophages identifies a predictive signature for inflammatory lung disease in preterm infants. Commun Biol. 2020 May 22; 3(1):259. Sahoo D, Zaramela LS, Hernandez GE, Mai U, Taheri S, Dang D, Stouch AN, Medal RM, McCoy AM, Aschner JL, Blackwell TS, Zengler K, Prince LS. PMID: 32444859.
      View in: PubMed   Mentions:
    12. Computational Approach to Identifying Universal Macrophage Biomarkers. Front Physiol. 2020; 11:275. Dang D, Taheri S, Das S, Ghosh P, Prince LS, Sahoo D. PMID: 32322218.
      View in: PubMed   Mentions:
    13. The stress polarity signaling (SPS) pathway serves as a marker and a target in the leaky gut barrier: implications in aging and cancer. Life Sci Alliance. 2020 03; 3(3). Ghosh P, Swanson L, Sayed IM, Mittal Y, Lim BB, Ibeawuchi SR, Foretz M, Viollet B, Sahoo D, Das S. PMID: 32041849.
      View in: PubMed   Mentions: 1     Fields:    
    14. Urothelial Proliferation of Unknown Malignant Potential Involving the Bladder: Histopathologic Features and Risk of Progression in De Novo Cases and Cases With Prior Neoplasia. Arch Pathol Lab Med. 2019 Dec 11. Lowenthal BM, Sahoo D, Amin MB, Hansel DE. PMID: 31825667.
      View in: PubMed   Mentions:    Fields:    
    15. Unbiased Boolean analysis of public gene expression data for cell cycle gene identification. Mol Biol Cell. 2019 07 01; 30(14):1770-1779. Dabydeen SA, Desai A, Sahoo D. PMID: 31091168.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    16. A predictive computational model reveals that GIV/girdin serves as a tunable valve for EGFR-stimulated cyclic AMP signals. Mol Biol Cell. 2019 06 15; 30(13):1621-1633. Getz M, Swanson L, Sahoo D, Ghosh P, Rangamani P. PMID: 31017840.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    17. Identification of gene expression logical invariants in Arabidopsis. Plant Direct. 2019 Mar; 3(3):e00123. Pandey S, Sahoo D. PMID: 31245766.
      View in: PubMed   Mentions:
    18. High fat diet induces sex-specific differential gene expression in Drosophila melanogaster. PLoS One. 2019; 14(3):e0213474. Stobdan T, Sahoo D, Azad P, Hartley I, Heinrichsen E, Zhou D, Haddad GG. PMID: 30861021.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    19. Convergence of Wnt, growth factor, and heterotrimeric G protein signals on the guanine nucleotide exchange factor Daple. Sci Signal. 2018 02 27; 11(519). Aznar N, Ear J, Dunkel Y, Sun N, Satterfield K, He F, Kalogriopoulos NA, Lopez-Sanchez I, Ghassemian M, Sahoo D, Kufareva I, Ghosh P. PMID: 29487190.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    20. Boolean analysis identifies CD38 as a biomarker of aggressive localized prostate cancer. Oncotarget. 2018 Jan 19; 9(5):6550-6561. Sahoo D, Wei W, Auman H, Hurtado-Coll A, Carroll PR, Fazli L, Gleave ME, Lin DW, Nelson PS, Simko J, Thompson IM, Leach RJ, Troyer DA, True LD, McKenney JK, Feng Z, Brooks JD. PMID: 29464091.
      View in: PubMed   Mentions: 2     Fields:    
    21. The innate immune response in fetal lung mesenchymal cells targets VEGFR2 expression and activity. . 2017 06 01; 312(6):L861-L872. Medal RM, Im AM, Yamamoto Y, Lakhdari O, Blackwell TS, Hoffman HM, Sahoo D, Prince LS. PMID: 28336813.
      View in: PubMed   Mentions:
    22. CDX2 as a Prognostic Biomarker in Stage II and Stage III Colon Cancer. N Engl J Med. 2016 Jan 21; 374(3):211-22. Dalerba P, Sahoo D, Paik S, Guo X, Yothers G, Song N, Wilcox-Fogel N, Forgó E, Rajendran PS, Miranda SP, Hisamori S, Hutchison J, Kalisky T, Qian D, Wolmark N, Fisher GA, van de Rijn M, Clarke MF. PMID: 26789870.
      View in: PubMed   Mentions: 111     Fields:    Translation:Humans
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