Gajanan Katkar

Title(s)	Assistant Project Scientist, Cellular and Molecular Medicine
School	Vc-health Sciences-schools
Address	9500 Gilman Drive # La Jolla CA 92093
ORCID	0000-0002-9982-8582
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Overview

Websites

	Gajanan Katkar
	Ghosh Lab
	HUMANOID Center of Research Excellence

Bibliographic

Publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.

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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.

Macrophage states: there's a method in the madness. Trends Immunol. 2023 12; 44(12):954-964. Katkar G, Ghosh P. PMID: 37945504.

View in: PubMed Mentions: 1 Fields:
All Allergy and Immunology
Translation:Humans Cells
Diverse gut pathogens exploit the host engulfment pathway via a conserved mechanism. J Biol Chem. 2023 Dec; 299(12):105390. Anandachar MS, Roy S, Sinha S, Boadi A, Katkar GD, Ghosh P. PMID: 37890785; PMCID: PMC10696401.

View in: PubMed Mentions: Fields:
Bio Biochemistry
Translation:Humans Animals Cells
Diverse Gut Pathogens Exploit the Host Engulfment Pathway via a Conserved Mechanism. bioRxiv. 2023 Aug 27. Anandachar MS, Roy S, Sinha S, Agyekum B, Ibeawuchi SR, Gementera H, Amamoto A, Katkar GD, Ghosh P. PMID: 37066267; PMCID: PMC10104235.

View in: PubMed Mentions:
Machine learning identifies signatures of macrophage reactivity and tolerance that predict disease outcomes. EBioMedicine. 2023 Aug; 94:104719. Ghosh P, Sinha S, Katkar GD, Vo D, Taheri S, Dang D, Das S, Sahoo D. PMID: 37516087; PMCID: PMC10388732.

View in: PubMed Mentions: 3 Fields:
Gen Genetics Med Medicine (General)
Translation:Humans Animals Cells
A Living Organoid Biobank of Crohn's Disease Patients Reveals Molecular Subtypes for Personalized Therapeutics. bioRxiv. 2023 Mar 13. Tindle C, Katkar GD, Fonseca AG, Taheri S, Lee J, Maity P, Sayed IM, Ibeawuchi SR, Vidales E, Pranadinata RF, Fuller M, Stec DL, Anandachar MS, Perry K, Le HN, Ear J, Boland BS, Sandborn WJ, Sahoo D, Das S, Ghosh P. PMID: 36993763; PMCID: PMC10054961.

View in: PubMed Mentions:
Publisher Correction: An Artificial Intelligence-guided signature reveals the shared host immune response in MIS-C and Kawasaki disease. Nat Commun. 2022 Aug 11; 13(1):4729. Ghosh P, Katkar GD, Shimizu C, Kim J, Khandelwal S, Tremoulet AH, Kanegaye JT, Pediatric Emergency Medicine Kawasaki Disease Research Group, Bocchini J, Das S, Burns JC, Sahoo D. PMID: 35953486; PMCID: PMC9372045.

View in: PubMed Mentions: Fields:
Bio Biology Sci Science
COVID-19 lung disease shares driver AT2 cytopathic features with Idiopathic pulmonary fibrosis. EBioMedicine. 2022 Aug; 82:104185. Sinha S, Castillo V, Espinoza CR, Tindle C, Fonseca AG, Dan JM, Katkar GD, Das S, Sahoo D, Ghosh P. PMID: 35870428; PMCID: PMC9297827.

View in: PubMed Mentions: 16 Fields:
Gen Genetics Med Medicine (General)
Translation:Humans Animals Cells
COVID-19 lung disease shares driver AT2 cytopathic features with Idiopathic pulmonary fibrosis. bioRxiv. 2022 Jul 18. Sinha S, Castillo V, Espinoza CR, Tindle C, Fonseca AG, Dan JM, Katkar GD, Das S, Sahoo D, Ghosh P. PMID: 34873597; PMCID: PMC8647648.

View in: PubMed Mentions:
An Artificial Intelligence-guided signature reveals the shared host immune response in MIS-C and Kawasaki disease. Nat Commun. 2022 05 16; 13(1):2687. Ghosh P, Katkar GD, Shimizu C, Kim J, Khandelwal S, Tremoulet AH, Kanegaye JT, Pediatric Emergency Medicine Kawasaki Disease Research Group, Bocchini J, Das S, Burns JC, Sahoo D. PMID: 35577777; PMCID: PMC9110726.

View in: PubMed Mentions: 23 Fields:
Bio Biology Sci Science
Translation:Humans Cells PHPublic Health
Artificial intelligence-rationalized balanced PPARα/γ dual agonism resets dysregulated macrophage processes in inflammatory bowel disease. Commun Biol. 2022 03 14; 5(1):231. Katkar GD, Sayed IM, Anandachar MS, Castillo V, Vidales E, Toobian D, Usmani F, Sawires JR, Leriche G, Yang J, Sandborn WJ, Das S, Sahoo D, Ghosh P. PMID: 35288651; PMCID: PMC8921270.

View in: PubMed Mentions: 4 Translation:Humans Animals Cells
Parsing the Role of PPARs in Macrophage Processes. Front Immunol. 2021; 12:783780. Toobian D, Ghosh P, Katkar GD. PMID: 35003101; PMCID: PMC8727354.

View in: PubMed Mentions: 20 Fields:
All Allergy and Immunology
GIV/Girdin, a non-receptor modulator for Gαi/s, regulates spatiotemporal signaling during sperm capacitation and is required for male fertility. Elife. 2021 08 19; 10. Reynoso S, Castillo V, Katkar GD, Lopez-Sanchez I, Taheri S, Espinoza C, Rohena C, Sahoo D, Gagneux P, Ghosh P. PMID: 34409938; PMCID: PMC8376251.

View in: PubMed Mentions: 2 Fields:
Bio Biology
Translation:Humans Animals Cells
Adult stem cell-derived complete lung organoid models emulate lung disease in COVID-19. Elife. 2021 08 13; 10. Tindle C, Fuller M, Fonseca A, Taheri S, Ibeawuchi SR, Beutler N, Katkar GD, Claire A, Castillo V, Hernandez M, Russo H, Duran J, Crotty Alexander LE, Tipps A, Lin G, Thistlethwaite PA, Chattopadhyay R, Rogers TF, Sahoo D, Ghosh P, Das S. PMID: 34463615; PMCID: PMC8463074.

View in: PubMed Mentions: 50 Fields:
Bio Biology
Translation:Humans Cells
An AI-guided signature reveals the nature of the shared proximal pathways of host immune response in MIS-C and Kawasaki disease. bioRxiv. 2021 Aug 09. Sahoo D, Katkar GD, Shimizu C, Kim J, Khandelwal S, Tremoulet AH, Kanegaye J, Pediatric Emergency Medicine Kawasaki Disease Research Group, Bocchini J, Das S, Burns JC, Ghosh P. PMID: 33880476; PMCID: PMC8057241.

View in: PubMed Mentions:
Artificial intelligence guided discovery of a barrier-protective therapy in inflammatory bowel disease. Nat Commun. 2021 07 12; 12(1):4246. Sahoo D, Swanson L, Sayed IM, Katkar GD, Ibeawuchi SR, Mittal Y, Pranadinata RF, Tindle C, Fuller M, Stec DL, Chang JT, Sandborn WJ, Das S, Ghosh P. PMID: 34253728; PMCID: PMC8275683.

View in: PubMed Mentions: 19 Fields:
Bio Biology Sci Science
Translation:Humans Animals
AI-guided discovery of the invariant host response to viral pandemics. EBioMedicine. 2021 Jun; 68:103390. Sahoo D, Katkar GD, Khandelwal S, Behroozikhah M, Claire A, Castillo V, Tindle C, Fuller M, Taheri S, Rogers TF, Beutler N, Ramirez SI, Rawlings SA, Pretorius V, Smith DM, Burton DR, Alexander LEC, Duran J, Crotty S, Dan JM, Das S, Ghosh P. PMID: 34127431; PMCID: PMC8193764.

View in: PubMed Mentions: 22 Fields:
Gen Genetics Med Medicine (General)
Translation:Humans Animals PHPublic Health
A first-in-class anticancer dual HDAC2/FAK inhibitors bearing hydroxamates/benzamides capped by pyridinyl-1,2,4-triazoles. Eur J Med Chem. 2021 Oct 15; 222:113569. Mustafa M, Abd El-Hafeez AA, Abdelhamid D, Katkar GD, Mostafa YA, Ghosh P, Hayallah AM, Abuo-Rahma GEA. PMID: 34111829; PMCID: PMC8818328.

View in: PubMed Mentions: 7 Fields:
Che Chemistry
Translation:Humans Cells
Chromogranin A regulates gut permeability via the antagonistic actions of its proteolytic peptides. Acta Physiol (Oxf). 2021 06; 232(2):e13655. Muntjewerff EM, Tang K, Lutter L, Christoffersson G, Nicolasen MJT, Gao H, Katkar GD, Das S, Ter Beest M, Ying W, Ghosh P, El Aidy S, Oldenburg B, van den Bogaart G, Mahata SK. PMID: 33783968; PMCID: PMC8341099.

View in: PubMed Mentions: 11 Fields:
Phy Physiology
Translation:Humans Animals Cells
Adult Stem Cell-derived Complete Lung Organoid Models Emulate Lung Disease in COVID-19. bioRxiv. 2021 May 05. Tindle C, Fuller M, Fonseca A, Taheri S, Ibeawuchi SR, Beutler N, Katkar G, Claire A, Castillo V, Hernandez M, Russo H, Duran J, Crotty Alexander LE, Tipps A, Lin G, Thistlethwaite PA, Chattopadhyay R, Rogers TF, Sahoo D, Ghosh P, Das S. PMID: 33106807; PMCID: PMC7587781.

View in: PubMed Mentions:
AI-guided discovery of the invariant host response to viral pandemics. bioRxiv. 2021 Apr 13. Sahoo D, Katkar GD, Khandelwal S, Behroozikhah M, Claire A, Castillo V, Tindle C, Fuller M, Taheri S, Rogers TF, Beutler N, Ramirez SI, Rawlings SA, Pretorius V, Smith DM, Burton DR, Alexander LEC, Duran J, Crotty S, Dan JM, Das S, Ghosh P. PMID: 32995790; PMCID: PMC7523116.

View in: PubMed Mentions:
TLR4 signaling and macrophage inflammatory responses are dampened by GIV/Girdin. Proc Natl Acad Sci U S A. 2020 10 27; 117(43):26895-26906. Swanson L, Katkar GD, Tam J, Pranadinata RF, Chareddy Y, Coates J, Anandachar MS, Castillo V, Olson J, Nizet V, Kufareva I, Das S, Ghosh P. PMID: 33055214; PMCID: PMC7604444.

View in: PubMed Mentions: 28 Fields:
Sci Science
Translation:Humans Animals Cells
Host engulfment pathway controls inflammation in inflammatory bowel disease. FEBS J. 2020 09; 287(18):3967-3988. Sayed IM, Suarez K, Lim E, Singh S, Pereira M, Ibeawuchi SR, Katkar G, Dunkel Y, Mittal Y, Chattopadhyay R, Guma M, Boland BS, Dulai PS, Sandborn WJ, Ghosh P, Das S. PMID: 32003126; PMCID: PMC7390677.

View in: PubMed Mentions: 26 Fields:
Bio Biochemistry
Translation:Humans Animals Cells
Research into the Causes of Venom-Induced Mortality and Morbidity Identifies New Therapeutic Opportunities. Am J Trop Med Hyg. 2019 05; 100(5):1043-1048. Girish KS, Katkar GD, Harrison RA, Kemparaju K. PMID: 30675839; PMCID: PMC6493937.

View in: PubMed Mentions: 1 Fields:
Tro Tropical Medicine
Translation:Humans Animals
Reply to 'Evidence that neutrophils do not promote Echis carinatus venom-induced tissue destruction'. Nat Commun. 2018 06 13; 9(1):2303. Kemparaju K, Girish KS, Katkar GD. PMID: 29899327; PMCID: PMC5998087.

View in: PubMed Mentions: Fields:
Bio Biology Sci Science
Translation:Animals Cells
Inhibition of Echis carinatus venom by DNA, a promising therapeutic molecule for snakebite management. Biochim Biophys Acta Gen Subj. 2018 May; 1862(5):1115-1125. Swethakumar B, NaveenKumar SK, Katkar GD, Girish KS, Kemparaju K. PMID: 29425807.

View in: PubMed Mentions: 1 Fields:
Bio Biochemistry Bio Biophysics
Translation:Humans Animals
Melatonin inhibits snake venom and antivenom induced oxidative stress and augments treatment efficacy. Acta Trop. 2017 May; 169:14-25. Sharma RD, Katkar GD, Sundaram MS, Swethakumar B, Girish KS, Kemparaju K. PMID: 28089603.

View in: PubMed Mentions: 3 Fields:
Tro Tropical Medicine
Translation:Animals
NETosis and lack of DNase activity are key factors in Echis carinatus venom-induced tissue destruction. Nat Commun. 2016 Apr 19; 7:11361. Katkar GD, Sundaram MS, NaveenKumar SK, Swethakumar B, Sharma RD, Paul M, Vishalakshi GJ, Devaraja S, Girish KS, Kemparaju K. PMID: 27093631; PMCID: PMC4838891.

View in: PubMed Mentions: 29 Fields:
Bio Biology Sci Science
Translation:Animals Cells
Lupeol derivative mitigates Echis carinatus venom-induced tissue destruction by neutralizing venom toxins and protecting collagen and angiogenic receptors on inflammatory cells. Biochim Biophys Acta. 2015 Dec; 1850(12):2393-409. Katkar GD, Sharma RD, Vishalakshi GJ, Naveenkumar SK, Madhur G, Thushara RM, Narender T, Girish KS, Kemparaju K. PMID: 26391844.

View in: PubMed Mentions: 3 Fields:
Bio Biochemistry Bio Biophysics
Translation:Humans Animals
Oxidative stress-induced methemoglobinemia is the silent killer during snakebite: a novel and strategic neutralization by melatonin. J Pineal Res. 2015 Sep; 59(2):240-54. Sharma RD, Katkar GD, Sundaram MS, Paul M, NaveenKumar SK, Swethakumar B, Hemshekhar M, Girish KS, Kemparaju K. PMID: 26103459.

View in: PubMed Mentions: 9 Fields:
End Endocrinology
Translation:Humans Animals
Melatonin alleviates Echis carinatus venom-induced toxicities by modulating inflammatory mediators and oxidative stress. J Pineal Res. 2014 Apr; 56(3):295-312. Katkar GD, Sundaram MS, Hemshekhar M, Sharma DR, Santhosh MS, Sunitha K, Rangappa KS, Girish KS, Kemparaju K. PMID: 24499241.

View in: PubMed Mentions: 11 Fields:
End Endocrinology
Translation:Animals