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Dennis Kuo

Title(s)Clinical Professor, Pediatrics
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    1. Project EVOLVE: an international analysis of postimmunotherapy lineage switch, an emergent form of relapse in leukemia. Blood. 2025 Jul 24; 146(4):437-455. Silbert SK, Rankin AW, Hoang CN, Semchenkova A, Myers RM, Zerkalenkova E, Wang HW, Kovach AE, Yuan CM, Delgado Colon D, Vasseur L, Bataller A, John S, Utley Lyons K, Friedes B, Alonso-Saladrigues A, Abdel-Azim H, Balducci E, Aljudi AA, Balsat M, Biery DN, Chamdin A, Chang BH, Cuevo RS, De Moerloose B, Dickens DS, Duffner U, Duployez N, El Chaer F, Elliott MA, Escherich G, Fernandes S, Fitzjohn MR, Gahvari Z, Grupp SA, He RR, Harrison C, Hergott CB, Hsieh EM, Kim AS, Kuo DJ, Larson DP, Lee BJ, Leguay T, Lindsley RC, Mangaonkar AA, Mezger K, Pacenta HL, Pan J, Provost M, Puri L, Raikar SS, Martinez A, Bristol I, Murphy K, Reiman L, Redell M, Reed K, Roth-Guepin G, Rubinstein J, Savasan S, Schafernak K, Stevens A, Talleur A, Torres Carapia N, Vargaftig J, Vatsayan A, Wölfl M, Zhao L, Rives S, Fabrizio VA, Sasaki K, Aldoss I, Boissel N, Rheingold SR, Davis KL, Ghorashian S, Jacoby E, Popov A, Lamble AJ, Shah NN. PMID: 40193715; PMCID: PMC12333221.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    2. Serum Carnitine Concentrations and Cardiac Function in Pediatric, Adolescent and Young Adult Oncology Patients Receiving High-Dose Anthracyclines. J Pediatr Pharmacol Ther. 2024 Oct; 29(5):475-481. Lin C, Narayan HK, Trovillion E, Armenian S, Alejandro L, Kuo DJ. PMID: 39411421; PMCID: PMC11472407.
      View in: PubMed   Mentions:
    3. Accidental Physical Trauma in Children and Youth with Special Health Care Needs: A Scoping Review. Acad Pediatr. 2025 03; 25(2):102590. Lillvis DF, Harmon B, Osei H, Ribeiro S, Zrik A, Janjua V, Assioun J, Aronoff N, Kuo DZ. PMID: 39395611.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    4. Pharmacogenomic Score Effectively Personalizes Treatment of Acute Myeloid Leukemia. Clin Cancer Res. 2024 Oct 01; 30(19):4388-4396. Marrero RJ, Wu H, Cao X, Parcha PK, Elsayed AH, Inaba H, Kuo DJ, Degar BA, Heym K, Taub JW, Lacayo N, Pui CH, Ribeiro RC, Rubnitz JE, Pounds SB, Lamba JK. PMID: 39078289; PMCID: PMC11444877.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    5. Parent and patient knowledge and attitudes about cancer predisposition syndrome genetic testing in pediatric oncology: Understanding sociodemographic and parent-child differences. Cancer Rep (Hoboken). 2024 Sep; 7(9):e2119. Rapoport CS, Masser-Frye D, Mehta S, Choi AK, Olfus S, Korhummel M, Hoyo V, Dimmock D, Malcarne VL, Kuo DJ. PMID: 39233650; PMCID: PMC11375323.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    6. Feasibility, reproducibility, and accuracy of echocardiographic right ventricular systolic function assessments in childhood cancer survivors at risk for heart failure. Echocardiography. 2024 Aug; 41(8):e15905. Ostler H, Liu L, Tong K, Acuero MT, Gomez-Arostegui J, Degner S, Choo S, Golding F, Hegde S, Kuo DJ, Narayan HK. PMID: 39158961; PMCID: PMC11338588.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    7. Pharmacogenomics, Race, and Treatment Outcome in Pediatric Acute Myeloid Leukemia. JAMA Netw Open. 2024 05 01; 7(5):e2411726. Lamba JK, Marrero R, Wu H, Cao X, Parcha PK, Karol SE, Inaba H, Kuo DJ, Degar BA, Heym K, Taub JW, Lacayo NJ, Pui CH, Ribeiro RC, Pounds SB, Rubnitz JE. PMID: 38753328; PMCID: PMC11099689.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    8. Clinical and biological landscape of constitutional mismatch-repair deficiency syndrome: an International Replication Repair Deficiency Consortium cohort study. Lancet Oncol. 2024 May; 25(5):668-682. Ercan AB, Aronson M, Fernandez NR, Chang Y, Levine A, Liu ZA, Negm L, Edwards M, Bianchi V, Stengs L, Chung J, Al-Battashi A, Reschke A, Lion A, Ahmad A, Lassaletta A, Reddy AT, Al-Darraji AF, Shah AC, Van Damme A, Bendel A, Rashid A, Margol AS, Kelly BL, Pencheva B, Heald B, Lemieux-Anglin B, Crooks B, Koschmann C, Gilpin C, Porter CC, Gass D, Samuel D, Ziegler DS, Blumenthal DT, Kuo DJ, Hamideh D, Basel D, Khuong-Quang DA, Stearns D, Opocher E, Carceller F, Baris Feldman H, Toledano H, Winer I, Scheers I, Fedorakova I, Su JM, Vengoechea J, Sterba J, Knipstein J, Hansford JR, Gonzales-Santos JR, Bhatia K, Bielamowicz KJ, Minhas K, Nichols KE, Cole KA, Penney L, Hjort MA, Sabel M, Gil-da-Costa MJ, Murray MJ, Miller M, Blundell ML, Massimino M, Al-Hussaini M, Al-Jadiry MF, Comito MA, Osborn M, Link MP, Zapotocky M, Ghalibafian M, Shaheen N, Mushtaq N, Waespe N, Hijiya N, Fuentes-Bolanos N, Ahmad O, Chamdine O, Roy P, Pichurin PN, Nyman P, Pearlman R, Auer RC, Sukumaran RK, Kebudi R, Dvir R, Raphael R, Elhasid R, McGee RB, Chami R, Noss R, Tanaka R, Raskin S, Sen S, Lindhorst S, Perreault S, Caspi S, Riaz S, Constantini S, Albert S, Chaleff S, Bielack S, Chiaravalli S, Cramer SL, Roy S, Cahn S, Penna S, Hamid SA, Ghafoor T, Imam U, Larouche V, Magimairajan Issai V, Foulkes WD, Lee YY, Nathan PC, Maruvka YE, Greer MC, Durno C, Shlien A, Ertl-Wagner B, Villani A, Malkin D, Hawkins C, Bouffet E, Das A, Tabori U. PMID: 38552658.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    9. Dose-Related Effect of Chemotherapy on Bone Mineral Density Among Pediatric Acute Lymphoblastic Leukemia Survivors. J Pediatr Pharmacol Ther. 2024; 29(1):53-60. Yamanishi AD, Determan D, Kuo DJ. PMID: 38332966; PMCID: PMC10849689.
      View in: PubMed   Mentions: 1  
    10. Malignant A-to-I RNA editing by ADAR1 drives T cell acute lymphoblastic leukemia relapse via attenuating dsRNA sensing. Cell Rep. 2024 02 27; 43(2):113704. Rivera M, Zhang H, Pham J, Isquith J, Zhou QJ, Balaian L, Sasik R, Enlund S, Mark A, Ma W, Holm F, Fisch KM, Kuo DJ, Jamieson C, Jiang Q. PMID: 38265938; PMCID: PMC10962356.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    11. Malignant A-to-I RNA editing by ADAR1 drives T-cell acute lymphoblastic leukemia relapse via attenuating dsRNA sensing. Res Sq. 2023 Jun 16. Rivera M, Zhang H, Pham J, Isquith J, Zhou QJ, Sasik R, Mark A, Ma W, Holm F, Fisch KM, Kuo DJ, Jamieson C, Jiang Q. PMID: 37398458; PMCID: PMC10312963.
      View in: PubMed   Mentions:
    12. Does Fever Response to Acetaminophen Predict Bloodstream Infections in Febrile Neutropenia? Cureus. 2023 Mar; 15(3):e36712. Mackie DB, Kuo D, Paul M, Elster J. PMID: 37113346; PMCID: PMC10129031.
      View in: PubMed   Mentions:
    13. Unmet Needs, Barriers, and Facilitators for Conducting Adolescent and Young Adult Cancer Survivorship Research in Southern California: A Delphi Survey. J Adolesc Young Adult Oncol. 2023 Oct; 12(5):765-772. Chan A, Ports K, Ng DQ, Nasr R, Hsu S, Armenian S, Baca N, Freyer DR, Kuo DJ, Lin C, Milam J, Valerin J, Yun C, Torno L. PMID: 36695742.
      View in: PubMed   Mentions: 3     Fields:    
    14. Cardiovascular toxicities with pediatric tyrosine kinase inhibitor therapy: An analysis of adverse events reported to the Food and Drug Administration. Pediatr Blood Cancer. 2023 02; 70(2):e30059. Narayan HK, Sheline K, Wong V, Kuo D, Choo S, Yoon J, Leger K, Kutty S, Fradley M, Tremoulet A, Ky B, Armenian S, Guha A. PMID: 36385736.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    15. Genome-Wide Association Study of Pregnancy in Childhood Cancer Survivors: A Report from the Childhood Cancer Survivor Study. Cancer Epidemiol Biomarkers Prev. 2022 09 02; 31(9):1858-1862. Rotz SJ, Worley S, Hu B, Bazeley P, Baedke JL, Hudson MM, Kuo DJ, Oeffinger KC, Robison LL, Sahoo D, Wang F, Yasui Y, Armstrong GT, Bhatia S. PMID: 35700038; PMCID: PMC9444932.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    16. Screening for Chemotherapy-induced Peripheral Neuropathy and Utilization of Physical Therapy in Pediatric Patients Receiving Treatment for Hematologic Malignancies. J Pediatr Hematol Oncol. 2022 Mar 01; 44(2):e358-e361. Wang CP, Syrkin-Nikolau M, Farnaes L, Shen D, Kanegaye M, Kuo DJ. PMID: 34001791.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    17. Tumor Genomic Profiling and Ex Vivo Drug Sensitivity Testing for Pediatric Leukemia and Lymphoma Patients. J Pediatr Pharmacol Ther. 2022; 27(2):123-131. Eaton A, Wong V, Schiff D, Anderson E, Ding H, Capparelli EV, Determan D, Kuo DJ. PMID: 35241983; PMCID: PMC8837212.
      View in: PubMed   Mentions: 4  
    18. Southern California Pediatric and Adolescent Cancer Survivorship (SC-PACS): Establishing a Multi-Institutional Childhood, Adolescent, and Young Adult Cancer Survivorship Consortium in Southern California. Cureus. 2022 Feb; 14(2):e21981. Lin C, Baca N, Yun C, Armenian S, Freyer DR, Majlessipour F, Mueller L, Kuo DJ, Casillas J, Zabokrtsky K, Ehwerhemuepha L, Torno L. PMID: 35282564; PMCID: PMC8906349.
      View in: PubMed   Mentions:
    19. Molecular and phenotypic diversity of CBL-mutated juvenile myelomonocytic leukemia. Haematologica. 2022 01 01; 107(1):178-186. Hecht A, Meyer JA, Behnert A, Wong E, Chehab F, Olshen A, Hechmer A, Aftandilian C, Bhat R, Choi SW, Chonat S, Farrar JE, Fluchel M, Frangoul H, Han JH, Kolb EA, Kuo DJ, MacMillan ML, Maese L, Maloney KW, Narendran A, Oshrine B, Schultz KR, Sulis ML, Van Mater D, Tasian SK, Hofmann WK, Loh ML, Stieglitz E. PMID: 33375775; PMCID: PMC8719097.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    20. Discordant end of induction bone marrow morphology and flow cytometry in a paediatric patient with acute myeloid leukaemia. BMJ Case Rep. 2021 Dec 31; 14(12). Breeding B, Bush KA, Kuo DJ. PMID: 34972789; PMCID: PMC8720989.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    21. Ultraviolet recall due to cytarabine chemotherapy for acute myeloid leukaemia. BMJ Case Rep. 2021 Nov 30; 14(11). Kuo DJ, Spies JM, Le Floch N, Wong V. PMID: 34848424; PMCID: PMC8634239.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    22. Improving vitamin D testing and supplementation in children with newly diagnosed cancer: A quality improvement initiative at Rady Children's Hospital San Diego. Pediatr Blood Cancer. 2021 11; 68(11):e29217. Shliakhtsitsava K, Fisher ES, Trovillion EM, Bush K, Kuo DJ, Newfield RS, Thornburg CD, Roberts W, Aristizabal P. PMID: 34286891; PMCID: PMC8463415.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    23. The Application of Next-generation Sequencing Tumor Molecular Profiling in the Diagnosis and Management of a Case of Acute Myelogenous Leukemia With MLL-PTD in a Pediatric Heart Transplant Recipient. J Pediatr Hematol Oncol. 2021 03 01; 43(2):e246-e249. Woolbright WC, Wong V, Severson E, Kuo DJ. PMID: 32134843.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    24. To test or not to test: genetic cancer predisposition testing in paediatric patients with cancer. J Med Ethics. 2020 Dec 10. Mehta S, Kuo DJ. PMID: 33303646.
      View in: PubMed   Mentions:    Fields:    
    25. Real-world data from a molecular tumor board demonstrates improved outcomes with a precision N-of-One strategy. Nat Commun. 2020 10 02; 11(1):4965. Kato S, Kim KH, Lim HJ, Boichard A, Nikanjam M, Weihe E, Kuo DJ, Eskander RN, Goodman A, Galanina N, Fanta PT, Schwab RB, Shatsky R, Plaxe SC, Sharabi A, Stites E, Adashek JJ, Okamura R, Lee S, Lippman SM, Sicklick JK, Kurzrock R. PMID: 33009371; PMCID: PMC7532150.
      View in: PubMed   Mentions: 154     Fields:    Translation:Humans
    26. Safety, pharmacokinetics, and pharmacodynamics of panobinostat in children, adolescents, and young adults with relapsed acute myeloid leukemia. Cancer. 2020 11 01; 126(21):4800-4805. Karol SE, Cooper TM, Mead PE, Crews KR, Panetta JC, Alexander TB, Taub JW, Lacayo NJ, Heym KM, Kuo DJ, Schiff DE, Bhojwani D, Ge Y, Klco JM, Ribeiro RC, Inaba H, Pui CH, Rubnitz JE. PMID: 32809242; PMCID: PMC7722063.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    27. Acute Megakaryoblastic Leukemia Leading to the Diagnosis of Germline Trisomy 21 Mosaicism. J Pediatr Hematol Oncol. 2020 05; 42(4):299-301. Savla D, Del Campo M, Masser-Frye D, Kuo DJ. PMID: 32068651.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    28. Yoga as a Complementary and Alternative Therapy in Children with Hematologic and Oncologic Disease. J Pediatr Oncol Nurs. 2020 Jul/Aug; 37(4):278-283. Fukuhara JS, O'Haver J, Proudfoot JA, Spies JM, Kuo DJ. PMID: 32167404; PMCID: PMC7797570.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    29. Leiomyosarcoma in Birt-Hogg-Dubé Syndrome. J Pediatr Hematol Oncol. 2020 03; 42(2):136-137. Bird LM, Kuo DJ, Masser-Frye D, Mo JQ, Elster JD. PMID: 31929385.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    30. Acute Pancreatitis Associated With Cytarabine During the Treatment of Pediatric Acute Myeloid Leukemia. J Pediatr Hematol Oncol. 2020 01; 42(1):63-64. Murshed F, Wong V, Koning JL, Kuo DJ. PMID: 31593004.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    31. Clinical Impact of Next-generation Sequencing in Pediatric Neuro-Oncology Patients: A Single-institutional Experience. Cureus. 2019 Dec 03; 11(12):e6281. Barsan V, Paul M, Gorsi H, Malicki D, Elster J, Kuo DJ, Crawford J. PMID: 31827999; PMCID: PMC6892579.
      View in: PubMed   Mentions: 5  
    32. Treatment of Recurrent Refractory Pediatric Pre-B Acute Lymphoblastic Leukemia Using Inotuzumab Ozogamicin Monotherapy Resulting in CD22 Antigen Expression Loss as a Mechanism of Therapy Resistance. J Pediatr Hematol Oncol. 2019 Nov; 41(8):e546-e549. Paul MR, Wong V, Aristizabal P, Kuo DJ. PMID: 30807395; PMCID: PMC7216755.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    33. Population pharmacokinetic analysis of high-dose methotrexate in pediatric and adult oncology patients. Cancer Chemother Pharmacol. 2019 12; 84(6):1339-1348. Kawakatsu S, Nikanjam M, Lin M, Le S, Saunders I, Kuo DJ, Capparelli EV. PMID: 31586225.
      View in: PubMed   Mentions: 26     Fields:    Translation:Humans
    34. Deep Vein Thrombosis in a Young, Healthy Baseball Catcher: A Case Report and Review of the Literature. J Pediatr Hematol Oncol. 2019 05; 41(4):321-323. Abood KK, Paul MR, Kuo DJ. PMID: 29401105; PMCID: PMC7216754.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    35. 'I just need an opiate refill to get me through the weekend'. J Med Ethics. 2019 04; 45(4):219-224. Yan E, Kuo DJ. PMID: 30796090.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansPHPublic Health
    36. MLL rearranged acute lymphoblastic leukaemia presenting as a maxillary sinus mass with a discordant immunophenotypic profile from the bone marrow. BMJ Case Rep. 2019 Feb 15; 12(2). Wang YM, Mo JQ, Kuo DJ, Wong V. PMID: 30772833; PMCID: PMC6388888.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    37. Multimodal Treatment of Rhinocerebral Mucormycosis in a Pediatric Patient With Relapsed Pre-B Acute Lymphoblastic Leukemia. Pediatr Infect Dis J. 2018 06; 37(6):555-558. Dworsky ZD, Bradley JS, Brigger MT, Pong AL, Kuo DJ. PMID: 29189615.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    38. Challenges of assessing response to therapy in non-Hodgkin's lymphoma of the bone. BMJ Case Rep. 2018 Apr 17; 2018. Paul MR, Kuo DJ. PMID: 29666085; PMCID: PMC5905781.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    39. Incidentally Detected Transfusion-associated Iron Overload in 3 Children After Cancer Chemotherapy. J Pediatr Hematol Oncol. 2018 04; 40(3):e164-e166. Kuo DJ, Bhagia P. PMID: 29300241.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    40. Obstructive sleep apnoea as a presenting manifestation of non-Hodgkin lymphoma in a child. Lancet Oncol. 2017 10; 18(10):e618. Ganesan AP, Jiang W, Kuo DJ, Bhattacharjee R. PMID: 28971828.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    41. Treatment of immune thrombocytopenic purpura associated with cytomegalovirus infection in a child with pre-B cell acute lymphoblastic leukaemia after central nervous system relapse. BMJ Case Rep. 2017 Sep 25; 2017. Martinez AR, Paul MR, Kuo DJ. PMID: 28947425; PMCID: PMC5747758.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    42. Unexpected diagnosis of appendicitis in a paediatric patient with febrile neutropaenia and acute myeloid leukaemia. BMJ Case Rep. 2017 Aug 07; 2017. Killian-Benigno C, Kuo DJ. PMID: 28784912; PMCID: PMC5624098.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    43. Persistent sacral chloroma in refractory acute myelogenous leukaemia. BMJ Case Rep. 2017 Jul 06; 2017. McCarty SM, Kuo DJ. PMID: 28687689; PMCID: PMC5534900.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    44. Severe medication-induced peripheral neuropathy treated with topical doxepin cream in a paediatric patient with leukaemia. BMJ Case Rep. 2017 May 22; 2017. Dworsky ZD, Bennett R, Kim JM, Kuo DJ. PMID: 28536226; PMCID: PMC5753714.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    45. Fever without a source: evolution of a diagnosis from Kawasaki disease to acute myelogenous leukaemia. BMJ Case Rep. 2017 May 06; 2017. Lee B, Kofman CD, Tremoulet AH, Kuo DJ. PMID: 28478386; PMCID: PMC5612012.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    46. Unilateral facial nerve palsy as an early presenting symptom of relapse in a paediatric patient with acute lymphoblastic leukaemia. BMJ Case Rep. 2017 Mar 10; 2017. Chiang LY, Crawford JR, Kuo DJ. PMID: 28283471; PMCID: PMC5353505.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    47. Identification of NTRK fusions in pediatric mesenchymal tumors. Pediatr Blood Cancer. 2017 Aug; 64(8). Pavlick D, Schrock AB, Malicki D, Stephens PJ, Kuo DJ, Ahn H, Turpin B, Allen JM, Rosenzweig M, Badizadegan K, Ross JS, Miller VA, Wong V, Ali SM. PMID: 28097808.
      View in: PubMed   Mentions: 37     Fields:    Translation:Humans
    48. Inadvertently boarding a pirate ship: disease progression in a paediatric patient with relapsed metastatic Ewing sarcoma receiving treatment at a centre for alternative therapy in Mexico. BMJ Case Rep. 2017 Jan 06; 2017. Cheng JH, Chiang LY, Kuo DJ. PMID: 28062429; PMCID: PMC5256570.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    49. Treatment of Metastatic, Refractory Alveolar Soft Part Sarcoma: Case Reports and Literature Review of Treatment Options in the Era of Targeted Therapy. J Pediatr Hematol Oncol. 2016 07; 38(5):e169-72. Kuo DJ, Menell JS, Glade Bender JL. PMID: 27164526.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
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