Robert Hoffman

Title(s)Recall Faculty, Surgery
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
vCardDownload vCard

    Collapse Overview 
    Collapse Overview
    Research Overview
    Our research program centers on cancer with the ultimate goal of developing a general cure.

    Research Topics
    - Angiogenesis
    - Cancer
    - Cell Biology
    - Development
    - Drug Delivery
    - Genetics
    - Genomics
    - Regeneration/Stem Cells
    - Translational Research

    Collapse Research 
    Collapse Research Activities and Funding
    Establishment of a patient-like mouse models of soft-tissue sarcoma sub-types
    NIH R43CA213649Dec 15, 2016 - Nov 30, 2017
    Role: Principal Investigator
    METHIONINE DEPENDENCE, METHYLATION AND ONCOGENESIS
    NIH K04CA000804Sep 1, 1982 - Aug 31, 1987
    Role: Principal Investigator
    METHIONINE DEPENDENCE, A METABOLIC MARKER IN CANCER
    NIH R01CA027564Sep 1, 1979 - Nov 30, 1993
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Deletion of MTAP Highly Sensitizes Osteosarcoma Cells to Methionine Restriction With Recombinant Methioninase. Cancer Genomics Proteomics. 2022 May-Jun; 19(3):299-304. Aoki Y, Tome Y, Han Q, Yamamoto J, Hamada K, Masaki N, Kubota Y, Bouvet M, Nishida K, Hoffman RM. PMID: 35430564; PMCID: PMC9016482.
      View in: PubMed   Mentions:
    2. Guanylate-binding Protein 2 Expression Is Associated With Poor Survival and Malignancy in Clear-cell Renal Cell Carcinoma. Anticancer Res. 2022 May; 42(5):2341-2354. Liu Q, Hoffman RM, Song J, Miao S, Zhang J, Ding D, Wang D. PMID: 35489720.
      View in: PubMed   Mentions:
    3. Stage IV Pancreatic Cancer Patient Treated With FOLFIRINOX Combined With Oral Methioninase: A Highly-Rare Case With Long-term Stable Disease. Anticancer Res. 2022 May; 42(5):2567-2572. Kubota Y, Han Q, Hozumi C, Masaki N, Yamamoto J, Aoki Y, Tsunoda T, Hoffman RM. PMID: 35489727.
      View in: PubMed   Mentions:
    4. Linkage of methionine addiction, histone lysine hypermethylation, and malignancy. iScience. 2022 Apr 15; 25(4):104162. Yamamoto J, Inubushi S, Han Q, Tashiro Y, Sugisawa N, Hamada K, Aoki Y, Miyake K, Matsuyama R, Bouvet M, Clarke SG, Endo I, Hoffman RM. PMID: 35434545; PMCID: PMC9010622.
      View in: PubMed   Mentions:
    5. TRAF6 regulates the signaling pathway influencing colorectal cancer function through ubiquitination mechanisms. Cancer Sci. 2022 Apr; 113(4):1393-1405. Guangwei Z, Zhibin C, Qin W, Chunlin L, Penghang L, Ruofan H, Hui C, Hoffman RM, Jianxin Y. PMID: 35179811; PMCID: PMC8990288.
      View in: PubMed   Mentions:
    6. Indocyanine Green Labeling of Tumors in the Liver Recurring After Radiofrequency Ablation Enables Complete Resection by Fluorescence-guided Surgery. Anticancer Res. 2022 Mar; 42(3):1345-1350. Tashiro Y, Aoki T, Hirai T, Koizumi T, Kusano T, Matsuda K, Yamada K, Nogaki K, Hakozaki T, Wada Y, Shibata H, Tomioka K, Yamazaki T, Saito K, Fujimori A, Enami Y, Hoffman RM. PMID: 35220226.
      View in: PubMed   Mentions:
    7. CHFR-Promoter-Methylation Status Is Predictive of Response to Irinotecan-based Systemic Chemotherapy in Advanced Colorectal Cancer. Anticancer Res. 2022 Feb; 42(2):697-707. Hagiwara T, Sugimoto K, Momose H, Irie T, Honjo K, Okazawa YU, Kawai M, Kawano S, Munakata S, Takahashi M, Kojima Y, Serizawa N, Nagahara A, Hoffman RM, Brock MV, Sakamoto K. PMID: 35093868.
      View in: PubMed   Mentions:
    8. Oral-recombinant Methioninase Converts an Osteosarcoma from Methotrexate-resistant to -sensitive in a Patient-derived Orthotopic-xenograft (PDOX) Mouse Model. Anticancer Res. 2022 Feb; 42(2):731-737. Aoki Y, Tome Y, Han Q, Yamamoto J, Hamada K, Masaki N, Kubota Y, Bouvet M, Nishida K, Hoffman RM. PMID: 35093871.
      View in: PubMed   Mentions:
    9. High Incidence of Lymph-node Metastasis in a Pancreatic-cancer Patient-derived Orthotopic Xenograft (PDOX) NOG-Mouse Model. Anticancer Res. 2022 Feb; 42(2):739-743. Sugisawa N, Miyake K, Higuchi T, Oshiro H, Park JH, Kawaguchi K, Bouvet M, Unno M, Hoffman RM. PMID: 35093872.
      View in: PubMed   Mentions:
    10. Methionine Restriction: Ready for Prime Time in the Cancer Clinic? Anticancer Res. 2022 Feb; 42(2):641-644. Yamamoto J, Han Q, Simon M, Thomas D, Hoffman RM. PMID: 35093861.
      View in: PubMed   Mentions:
    11. Chronic spinal cord injury functionally repaired by direct implantation of encapsulated hair-follicle-associated pluripotent (HAP) stem cells in a mouse model: Potential for clinical regenerative medicine. PLoS One. 2022; 17(1):e0262755. Obara K, Shirai K, Hamada Y, Arakawa N, Yamane M, Takaoka N, Aki R, Hoffman RM, Amoh Y. PMID: 35085322; PMCID: PMC8794105.
      View in: PubMed   Mentions:
    12. Fluorescence Molecular Targeting of Colon Cancer to Visualize the Invisible. Cells. 2022 01 12; 11(2). Lwin TM, Turner MA, Amirfakhri S, Nishino H, Hoffman RM, Bouvet M. PMID: 35053365; PMCID: PMC8773892.
      View in: PubMed   Mentions:
    13. Andrographolide, a diterpene lactone from the Traditional Chinese Medicine Andrographis paniculate, induces senescence in human lung adenocarcinoma via p53/p21 and Skp2/p27. Phytomedicine. 2022 Jan 10; 98:153933. Zhang J, Li C, Zhang L, Heng Y, Wang S, Pan Y, Cai L, Zhang Y, Xu T, Chen X, Hoffman RM, Jia L. PMID: 35121394.
      View in: PubMed   Mentions:
    14. Determinative Structural Features Identified With Probe-based Confocal Endomicroscopy for the Accurate Diagnosis of Gallbladder Malignancy. Anticancer Res. 2022 Jan; 42(1):67-73. Koizumi T, Aoki T, Yamochi T, Tashiro Y, Yamazaki T, Kusano T, Matsuda K, Wada Y, Shibata H, Saito K, Nogaki K, Hakozaki T, Tomioka K, Hirai T, Fujimori A, Mansour DA, Abbas Gahin AE, Hoffman RM. PMID: 34969710.
      View in: PubMed   Mentions:
    15. Extent and Instability of Trimethylation of Histone H3 Lysine Increases With Degree of Malignancy and Methionine Addiction. Cancer Genomics Proteomics. 2022 Jan-Feb; 19(1):12-18. Yamamoto J, Aoki Y, Inubushi S, Han Q, Hamada K, Tashiro Y, Miyake K, Matsuyama R, Bouvet M, Clarke SG, Endo I, Hoffman RM. PMID: 34949655; PMCID: PMC8717956.
      View in: PubMed   Mentions:
    16. Fluorescent Anti-MUC5AC Brightly Targets Pancreatic Cancer in a Patient-derived Orthotopic Xenograft. In Vivo. 2022 Jan-Feb; 36(1):57-62. Turner MA, Hollandsworth HM, Nishino H, Amirfakhri S, Lwin TM, Lowy AM, Kaur S, Natarajan G, Mallya K, Hoffman RM, Batra SK, Bouvet M. PMID: 34972700; PMCID: PMC8765132.
      View in: PubMed   Mentions:
    17. The cancer-inhibitory effects of proliferating tumor-residing fibroblasts. Biochim Biophys Acta Rev Cancer. 2022 01; 1877(1):188673. Delinassios JG, Hoffman RM. PMID: 34953931.
      View in: PubMed   Mentions:
    18. The Use of Fluorescent Anti-CEA Antibodies to Label, Resect and Treat Cancers: A Review. Biomolecules. 2021 12 02; 11(12). Turner MA, Lwin TM, Amirfakhri S, Nishino H, Hoffman RM, Yazaki PJ, Bouvet M. PMID: 34944463; PMCID: PMC8699160.
      View in: PubMed   Mentions:
    19. Osteosarcoma Patient-derived Orthotopic Xenograft (PDOX) Models Used to Identify Novel and Effective Therapeutics: A Review. Anticancer Res. 2021 Dec; 41(12):5865-5871. Higuchi T, Igarashi K, Yamamoto N, Hayashi K, Kimura H, Miwa S, Bouvet M, Tsuchiya H, Hoffman RM. PMID: 34848441.
      View in: PubMed   Mentions:
    20. A Case of Rare Matrix-producing Triple-negative Breast Carcinoma for Which Drug Response in a Patient-derived Orthotopic Xenograft Mouse Model Was Correlated With Patient Response. Anticancer Res. 2021 Dec; 41(12):6191-6197. Nomura T, Kurebayashi J, Moriya T, Saito W, Murata T, Yamamoto J, Hozumi C, Hoffman RM. PMID: 34848473.
      View in: PubMed   Mentions:
    21. Histone H3 lysine-trimethylation markers are decreased by recombinant methioninase and increased by methotrexate at concentrations which inhibit methionine-addicted osteosarcoma cell proliferation. Biochem Biophys Rep. 2021 Dec; 28:101177. Aoki Y, Tome Y, Han Q, Yamamoto J, Hamada K, Masaki N, Bouvet M, Nishida K, Hoffman RM. PMID: 34877414; PMCID: PMC8633566.
      View in: PubMed   Mentions:
    22. Survival Response of Patients With Gastric Cancer Treated With Regional Arterial-Perfusion Chemotherapy Is Correlated With Borrmann Classification. Anticancer Res. 2021 Nov; 41(11):5507-5515. Ma YE, Liang X, Liu LI, Gao D, Yang T, Hoffman RM, Xu J. PMID: 34732421.
      View in: PubMed   Mentions:
    23. Over-methylation of Histone H3 Lysines Is a Common Molecular Change Among the Three Major Types of Soft-tissue Sarcoma in Patient-derived Xenograft (PDX) Mouse Models. Cancer Genomics Proteomics. 2021 Nov-Dec; 18(6):715-721. Aoki Y, Yamamoto J, Tome Y, Hamada K, Masaki N, Inubushi S, Tashiro Y, Bouvet M, Endo I, Nishida K, Hoffman RM. PMID: 34697064; PMCID: PMC8569816.
      View in: PubMed   Mentions:
    24. Salmonella typhimurium A1-R Exquisitely Targets and Arrests a Matrix-producing Triple-negative Breast Carcinoma in a PDOX Model. In Vivo. 2021 Nov-Dec; 35(6):3067-3071. Hamada K, Aoki Y, Yamamoto J, Hozumi C, Zhao M, Murata T, Sugisawa N, Bouvet M, Tsunoda T, Hoffman RM. PMID: 34697138; PMCID: PMC8627766.
      View in: PubMed   Mentions:
    25. Osteosarcoma of the Breast in a Patient Derived Orthotopic Xenograft (PDOX) Mouse Model Is Arrested by both Cisplatinum and Eribulin. In Vivo. 2021 Nov-Dec; 35(6):3107-3110. Masaki N, Wu NF, Aoki Y, Yamamoto J, Miyazaki J, Hoffman RM. PMID: 34697141; PMCID: PMC8627742.
      View in: PubMed   Mentions:
    26. Preclinical characterization of an intravenous coronavirus 3CL protease inhibitor for the potential treatment of COVID19. Nat Commun. 2021 10 18; 12(1):6055. Boras B, Jones RM, Anson BJ, Arenson D, Aschenbrenner L, Bakowski MA, Beutler N, Binder J, Chen E, Eng H, Hammond H, Hammond J, Haupt RE, Hoffman R, Kadar EP, Kania R, Kimoto E, Kirkpatrick MG, Lanyon L, Lendy EK, Lillis JR, Logue J, Luthra SA, Ma C, Mason SW, McGrath ME, Noell S, Obach RS, O' Brien MN, O'Connor R, Ogilvie K, Owen D, Pettersson M, Reese MR, Rogers TF, Rosales R, Rossulek MI, Sathish JG, Shirai N, Steppan C, Ticehurst M, Updyke LW, Weston S, Zhu Y, White KM, García-Sastre A, Wang J, Chatterjee AK, Mesecar AD, Frieman MB, Anderson AS, Allerton C. PMID: 34663813; PMCID: PMC8523698.
      View in: PubMed   Mentions:    Fields:    
    27. The Combination of Cisplatinum and Doxorubicin Regressed Primary Osteosarcoma of the Breast in a PDOX Mouse Model. Anticancer Res. 2021 Oct; 41(10):4715-4718. Wu NF, Yamamoto J, Aoki Y, Masaki N, Samonte C, Wu J, Bouvet M, Hoffman RM. PMID: 34593419.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    28. Anti-inflammatory and Anti-thrombotic Efficacy of Targeted Ultrasound Microbubbles on LPS-induced HUVEC Cells. Anticancer Res. 2021 Oct; 41(10):4761-4769. Sun J, Pan S, Yu H, Hu H, Sun YU, Yang Z, Hoffman RM, Yuan H. PMID: 34593425.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    29. Antibiotic Usage Reduced Overall Survival by over 70% in Non-small Cell Lung Cancer Patients on Anti-PD-1 Immunotherapy. Anticancer Res. 2021 Oct; 41(10):4985-4993. Hamada K, Yoshimura K, Hirasawa Y, Hosonuma M, Murayama M, Narikawa Y, Ariizumi H, Ohkuma R, Shida M, Kubota Y, Matsukuma S, Ishiguro T, Sambe T, Horiike A, Kuramasu A, Wada S, Tsurutani J, Inoue E, Uchida N, Kiuchi Y, Kobayashi S, Hoffman RM, Tsunoda T. PMID: 34593446.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    30. Efficacy of Oral Recombinant Methioninase and Eribulin on a PDOX Model of Triple-negative Breast Cancer (TNBC) Liver Metastasis. In Vivo. 2021 Sep-Oct; 35(5):2531-2534. Lim HI, Sun YU, Han Q, Yamamoto J, Hoffman RM. PMID: 34410939; PMCID: PMC8408690.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    31. Multikinase-Inhibitor Screening in Drug-resistant Osteosarcoma Patient-derived Orthotopic Xenograft Mouse Models Identifies the Clinical Potential of Regorafenib. Cancer Genomics Proteomics. 2021 Sep-Oct; 18(5):637-643. Higuchi T, Igarashi K, Yamamoto N, Hayashi K, Kimura H, Miwa S, Bouvet M, Tsuchiya H, Hoffman RM. PMID: 34479916; PMCID: PMC8441758.
      View in: PubMed   Mentions:    Fields:    
    32. Five-day water-only fasting decreased metabolic-syndrome risk factors and increased anti-aging biomarkers without toxicity in a clinical trial of normal-weight individuals. Clin Transl Med. 2021 08; 11(8):e502. Jiang Y, Yang X, Dong C, Lu Y, Yin H, Xiao B, Yang X, Chen W, Cheng W, Tian H, Guo L, Hu X, Fang H, Chen W, Li Z, Zhou W, Sun W, Guo X, Li S, Lin Y, He R, Chen X, Liu D, Zhang M, Zhang Y, Zhao H, Zheng P, Seyfried TN, Hoffman RM, Jia W, Ji G, Jia L. PMID: 34459130; PMCID: PMC8320652.
      View in: PubMed   Mentions:
    33. Indocyanine Green Fluorescence Image-guided Laparoscopic Hepatectomy Enabled Resection of a Tumor Invisible With Ultrasonography. Anticancer Res. 2021 Aug; 41(8):3867-3869. Oura K, Aoki T, Tashiro Y, Matsuda K, Koizumi T, Kusano T, Wada Y, Shibata H, Yamashita T, Date H, Ariyoshi T, Goto S, Yamazaki K, Watanabe M, Fujimori A, Enami Y, Otsuka K, Hoffman RM, Murakami M. PMID: 34281847.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    34. Rapid tumor-labeling kinetics with a site-specific near-infrared anti-CEA nanobody in a patient-derived orthotopic xenograft mouse model of colon cancer. J Surg Oncol. 2021 Dec; 124(7):1121-1127. Lwin TM, Turner MA, Amirfakhri S, Nishino H, Debie P, Cosman BC, Hoffman RM, Hernot S, Bouvet M. PMID: 34309885; PMCID: PMC8556245.
      View in: PubMed   Mentions:    Fields:    
    35. A Patient-Derived Orthotopic Xenograft Model of Gastroesophageal-Junction Adenocarcinoma Translated to the Clinic by Tumor-Targeting Fluorescent Antibodies to Carcinoembryonic-Antigen-Related Cell-Adhesion Molecules. In Vivo. 2021 Jul-Aug; 35(4):1959-1963. Turner MA, Amirfakhri S, Nishino H, Lwin TM, Savides TJ, Reid TR, Singer BB, Hoffman RM, Bouvet M. PMID: 34182469; PMCID: PMC8286470.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    36. The First Mouse Model of Primary Osteosarcoma of the Breast. In Vivo. 2021 Jul-Aug; 35(4):1979-1983. Wu NF, Wu J, Yamamoto J, Aoki Y, Hozumi C, Bouvet M, Hoffman RM. PMID: 34182472; PMCID: PMC8286515.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    37. Traditional Chinese Medicine Xihuang Wan Inhibited Lewis Lung Carcinoma in a Syngeneic Model, Equivalent to Cytotoxic Chemotherapy, by Altering Multiple Signaling Pathways. In Vivo. 2021 Jul-Aug; 35(4):2005-2014. Zhang Z, Wang J, Duan H, Liu D, Zhou X, Lin X, Pang H, Sun M, Zhou T, Hoffman RM, Hu K. PMID: 34182475; PMCID: PMC8286502.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    38. Chronic Treatment of an Advanced Prostate-cancer Patient With Oral Methioninase Resulted in Long-term Stabilization of Rapidly Rising PSA Levels. In Vivo. 2021 Jul-Aug; 35(4):2171-2176. Han Q, Hoffman RM. PMID: 34182494; PMCID: PMC8286516.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    39. Combination of CDK4/6 and mTOR Inhibitors Suppressed Doxorubicin-resistant Osteosarcoma in a Patient-derived Orthotopic Xenograft Mouse Model: A Translatable Strategy for Recalcitrant Disease. Anticancer Res. 2021 Jul; 41(7):3287-3292. Oshiro H, Tome Y, Miyake K, Higuchi T, Sugisawa N, Kanaya F, Nishida K, Hoffman RM. PMID: 34230123.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    40. Immuno-hyperthermia effected by antibody-conjugated nanoparticles selectively targets and eradicates individual cancer cells. Cell Cycle. 2021 07; 20(13):1221-1230. Kagawa T, Matsumi Y, Aono H, Ohara T, Tazawa H, Shigeyasu K, Yano S, Takeda S, Komatsu Y, Hoffman RM, Fujiwara T, Kishimoto H. PMID: 34148497; PMCID: PMC8330994.
      View in: PubMed   Mentions:    Fields:    
    41. Effective Tumor Targeting by EphA2-Agonist-Biotin-Streptavidin Conjugates. Molecules. 2021 Jun 17; 26(12). Udompholkul P, Baggio C, Gambini L, Sun Y, Zhao M, Hoffman RM, Pellecchia M. PMID: 34204178; PMCID: PMC8235110.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    42. Fangchinoline Inhibits Human Esophageal Cancer by Transactivating ATF4 to Trigger Both Noxa-Dependent Intrinsic and DR5-Dependent Extrinsic Apoptosis. Front Oncol. 2021; 11:666549. Zhang Y, Wang S, Chen Y, Zhang J, Yang J, Xian J, Li L, Zhao H, Hoffman RM, Zhang Y, Jia L. PMID: 34195076; PMCID: PMC8236818.
      View in: PubMed   Mentions: 1  
    43. Hyperthermia generated by magnetic nanoparticles for effective treatment of disseminated peritoneal cancer in an orthotopic nude-mouse model. Cell Cycle. 2021 06; 20(12):1122-1133. Matsumi Y, Kagawa T, Yano S, Tazawa H, Shigeyasu K, Takeda S, Ohara T, Aono H, Hoffman RM, Fujiwara T, Kishimoto H. PMID: 34110969; PMCID: PMC8265816.
      View in: PubMed   Mentions: 1     Fields:    
    44. Neddylation Regulates Macrophages and Implications for Cancer Therapy. Front Cell Dev Biol. 2021; 9:681186. Jiang Y, Li L, Li Y, Liu G, Hoffman RM, Jia L. PMID: 34164400; PMCID: PMC8215544.
      View in: PubMed   Mentions:
    45. Exosome Transfer Between Pancreatic-cancer Cells Is Associated With Metastasis in a Nude-mouse Model. Anticancer Res. 2021 Jun; 41(6):2829-2834. Ichikawa H, Suetsugu A, Satake T, Aoki H, Kunisada T, Shimizu M, Hoffman RM. PMID: 34083272.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    46. Traditional Chinese Medicine Brucea Javanica Oil Enhances the Efficacy of Anlotinib in a Mouse Model of Liver-Metastasis of Small-cell Lung Cancer. In Vivo. 2021 May-Jun; 35(3):1437-1441. Peng S, Dong W, Chu Q, Meng J, Yang H, DU Y, Sun YU, Hoffman RM. PMID: 33910820; PMCID: PMC8193324.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    47. Efficacy of YAP1-gene Knockdown to Inhibit Alveolar-Epithelial-Cell Senescence and Alleviate Idiopathic Pulmonary Fibrosis (IPF). Cancer Genomics Proteomics. 2021 May-Jun; 18(3 Suppl):451-459. Xu W, Song W, Wang YU, Zan Y, Zhang M, Li M, Huang Q, Zhao W, Sun YU, Hoffman RM, Wu J. PMID: 33994367; PMCID: PMC8240039.
      View in: PubMed   Mentions:    Fields:    
    48. Andrographolide Induces Noxa-Dependent Apoptosis by Transactivating ATF4 in Human Lung Adenocarcinoma Cells. Front Pharmacol. 2021; 12:680589. Zhang J, Li C, Zhang L, Heng Y, Xu T, Zhang Y, Chen X, Hoffman RM, Jia L. PMID: 33995110; PMCID: PMC8117100.
      View in: PubMed   Mentions:
    49. An mTOR and VEGFR inhibitor combination arrests a doxorubicin resistant lung metastatic osteosarcoma in a PDOX mouse model. Sci Rep. 2021 04 21; 11(1):8583. Oshiro H, Tome Y, Miyake K, Higuchi T, Sugisawa N, Kanaya F, Nishida K, Hoffman RM. PMID: 33883561; PMCID: PMC8060249.
      View in: PubMed   Mentions: 1     Fields:    
    50. Hair-Follicle-Associated Pluripotent (HAP) Stem Cells Can Extensively Differentiate to Tyrosine-Hydroxylase-Expressing Dopamine-Secreting Neurons. Cells. 2021 04 10; 10(4). Yamane M, Takaoka N, Obara K, Shirai K, Aki R, Hamada Y, Arakawa N, Hoffman RM, Amoh Y. PMID: 33920157; PMCID: PMC8069047.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    51. A Novel Color-Coded Liver Metastasis Mouse Model to Distinguish Tumor and Adjacent Liver Segment. J Surg Res. 2021 08; 264:327-333. Nishino H, Hollandsworth HM, Amirfakhri S, Tashiro Y, Yamamoto J, Turner MA, Lwin TM, Singer BB, Hoffman RM, Bouvet M. PMID: 33848831; PMCID: PMC8222089.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    52. Oral-recombinant Methioninase Converts an Osteosarcoma from Docetaxel-resistant to -Sensitive in a Clinically-relevant Patient-derived Orthotopic-xenograft (PDOX) Mouse Model. Anticancer Res. 2021 Apr; 41(4):1745-1751. Aoki Y, Tome Y, Wu NF, Yamamoto J, Hamada K, Han Q, Bouvet M, Nishida K, Hoffman RM. PMID: 33813378.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    53. Eribulin Inhibits Osteosarcoma in a Clinically-accurate Bone-tumor-insertion PDOX Mouse Model. Anticancer Res. 2021 Apr; 41(4):1779-1784. Wu NF, Yamamoto J, Aoki Y, Bouvet M, Hoffman RM. PMID: 33813382.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    54. Lowering and Stabilizing PSA Levels in Advanced-prostate Cancer Patients With Oral Methioninase. Anticancer Res. 2021 Apr; 41(4):1921-1926. Han Q, Hoffman RM. PMID: 33813397.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCellsCTClinical Trials
    55. Oral recombinant methioninase combined with paclitaxel arrests recalcitrant ovarian clear cell carcinoma growth in a patient-derived orthotopic xenograft (PDOX) nude-mouse model. Cancer Chemother Pharmacol. 2021 07; 88(1):61-67. Sugisawa N, Higuchi T, Han Q, Hozumi C, Yamamoto J, Tashiro Y, Nishino H, Kawaguchi K, Bouvet M, Murata T, Unno M, Hoffman RM. PMID: 33768300.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    56. Overexpressed NEDD8 as a potential therapeutic target in esophageal squamous cell carcinoma. Cancer Biol Med. 2021 Mar 18. Xian J, Wang S, Jiang Y, Li L, Cai L, Chen P, Liu Y, Zeng X, Chen G, Ding C, Hoffman RM, Jia L, Zhao H, Zhang Y. PMID: 33733647.
      View in: PubMed   Mentions: 1  
    57. The Anti-oxidant Monoterpene p-Cymene Reduced the Occurrence of Colorectal Cancer in a Hyperlipidemia Rat Model by Reducing Oxidative Stress and Expression of Inflammatory Cytokines. Anticancer Res. 2021 Mar; 41(3):1213-1218. Wang S, Wang X, Wang YU, Leng Q, Sun YU, Hoffman RM, Jin H. PMID: 33788712.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    58. The Experience of Greece as a Model to Contain COVID-19 Infection Spread. In Vivo. 2021 Mar-Apr; 35(2):1285-1294. Delinasios GJ, Fragkou PC, Gkirmpa AM, Tsangaris G, Hoffman RM, Anagnostopoulos AK. PMID: 33622932; PMCID: PMC8045105.
      View in: PubMed   Mentions:    Fields:    Translation:HumansPHPublic Health
    59. Combination Methionine-methylation-axis Blockade: A Novel Approach to Target the Methionine Addiction of Cancer. Cancer Genomics Proteomics. 2021 Mar-Apr; 18(2):113-120. Higuchi T, Han Q, Sugisawa N, Yamamoto J, Yamamoto N, Hayashi K, Kimura H, Miwa S, Igarashi K, Bouvet M, Singh SR, Tsuchiya H, Hoffman RM. PMID: 33608308; PMCID: PMC7943212.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    60. Unique Benefits of Tumor-Specific Nanobodies for Fluorescence Guided Surgery. Biomolecules. 2021 02 18; 11(2). Lwin TM, Hoffman RM, Bouvet M. PMID: 33670740; PMCID: PMC7921980.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    61. A Novel Orthotopic Mouse Model of Lung Metastasis Using Fluorescent Patient-derived Osteosarcoma Cells. Anticancer Res. 2021 Feb; 41(2):635-640. Oshiro H, Tome Y, Miyake K, Higuchi T, Sugisawa N, Park JH, Zhang Z, Razmjooei S, Kanaya F, Nishida K, Hoffman RM. PMID: 33517267.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    62. Reversion from Methionine Addiction to Methionine Independence Results in Loss of Tumorigenic Potential of Highly-malignant Lung-cancer Cells. Anticancer Res. 2021 Feb; 41(2):641-643. Yamamoto J, Aoki Y, Han Q, Sugisawa N, Sun YU, Hamada K, Nishino H, Inubushi S, Miyake K, Matsuyama R, Bouvet M, Endo I, Hoffman RM. PMID: 33517268.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    63. Real-Time Fluorescence Image-Guided Oncolytic Virotherapy for Precise Cancer Treatment. Int J Mol Sci. 2021 Jan 17; 22(2). Yano S, Tazawa H, Kishimoto H, Kagawa S, Fujiwara T, Hoffman RM. PMID: 33477279; PMCID: PMC7830621.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    64. Color-Coded Imaging of Cancer and Stromal-Cell Interaction in the Pancreatic-Cancer Tumor Microenvironment (TME). Methods Mol Biol. 2021; 2224:99-111. Suetsugu A, Hoffman RM. PMID: 33606209.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    65. Triple-Methyl Blockade With Recombinant Methioninase, Cycloleucine, and Azacitidine Arrests a Pancreatic Cancer Patient-Derived Orthotopic Xenograft Model. Pancreas. 2021 01 01; 50(1):93-98. Sugisawa N, Yamamoto J, Han Q, Tan Y, Tashiro Y, Nishino H, Inubushi S, Hamada K, Kawaguchi K, Unno M, Bouvet M, Hoffman RM. PMID: 33370029.
      View in: PubMed   Mentions: 2     Fields:    
    66. A Novel Procedure for Orthotopic Tibia Implantation for Establishment of a More Clinical Osteosarcoma PDOX Mouse Model. In Vivo. 2021 Jan-Feb; 35(1):105-109. Wu NF, Yamamoto J, Bouvet M, Hoffman RM. PMID: 33402455; PMCID: PMC7880751.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    67. Color-Coded Imaging of the Tumor Microenvironment (TME) in Human Patient-Derived Orthotopic Xenograft (PDOX) Mouse Models. Adv Exp Med Biol. 2021; 1329:163-179. Suetsugu A, Hoffman RM. PMID: 34664239.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    68. A Universal Gelfoam 3-D Histoculture Method to Establish Patient-derived Cancer Cells (3D-PDCC) Without Fibroblasts from Patient-derived Xenografts. Anticancer Res. 2020 Dec; 40(12):6765-6768. Yamamoto J, Sugisawa N, Hamada K, Nishino H, Miyake K, Matsuyama R, Inubushi S, Tanino H, Bouvet M, Endo I, Hoffman RM. PMID: 33288569.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    69. A review of tumor-specific fluorescence-guided surgery for colorectal cancer. Surg Oncol. 2021 Mar; 36:84-90. Hollandsworth HM, Turner MA, Hoffman RM, Bouvet M. PMID: 33316684; PMCID: PMC7855598.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    70. A novel patient-derived orthotopic xenograft (PDOX) mouse model of highly-aggressive liver metastasis for identification of candidate effective drug-combinations. Sci Rep. 2020 11 18; 10(1):20105. Zhang Z, Hu K, Miyake K, Kiyuna T, Oshiro H, Wangsiricharoen S, Kawaguchi K, Higuchi T, Razmjooei S, Miyake M, Chawla SP, Singh SR, Hoffman RM. PMID: 33208807; PMCID: PMC7676248.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    71. Oral Recombinant Methioninase Sensitizes a Bladder Cancer Orthotopic Xenograft Mouse Model to Low-dose Cisplatinum and Prevents Metastasis. Anticancer Res. 2020 Nov; 40(11):6083-6091. Sun YU, Nishino H, Sugisawa N, Yamamoto J, Hamada K, Zhu G, Lim HI, Hoffman RM. PMID: 33109546.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    72. Sutureless Surgical Orthotopic Implantation Technique of Primary and Metastatic Cancer in the Liver of Mouse Models. In Vivo. 2020 Nov-Dec; 34(6):3153-3157. Nishino H, Hollandsworth HM, Sugisawa N, Yamamoto J, Tashiro Y, Inubushi S, Hamada K, Sun YU, Lim H, Amirfakhri S, Filemoni F, Hoffman RM, Bouvet M. PMID: 33144418; PMCID: PMC7811661.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    73. Ligation Method to Specifically Label a Liver Segment With Indocyanine Green in an Orthotopic Nude-Mouse Liver-Metastasis Model. In Vivo. 2020 Nov-Dec; 34(6):3159-3162. Nishino H, Hollandsworth HM, Tashiro Y, Yamamoto J, Amirfakhri S, Filemoni F, Sugisawa N, Hoffman RM, Bouvet M. PMID: 33144419; PMCID: PMC7811678.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    74. Response of Triple-negative Breast Cancer Liver Metastasis to Oral Recombinant Methioninase in a Patient-derived Orthotopic Xenograft (PDOX) Model. In Vivo. 2020 Nov-Dec; 34(6):3163-3169. Lim HI, Yamamoto J, Han Q, Sun YU, Nishino H, Tashiro Y, Sugisawa N, Tan Y, Choi HJ, Nam SJ, Bouvet M, Hoffman RM. PMID: 33144420; PMCID: PMC7811664.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    75. A Non-invasive Imageable GFP-expressing Mouse Model of Orthotopic Human Bladder Cancer. In Vivo. 2020 Nov-Dec; 34(6):3225-3231. Sun YU, Nishino H, Zhao M, Miyake K, Sugisawa N, Yamamoto J, Tashiro Y, Inubushi S, Hamada K, Zhu G, Lim H, Hoffman RM. PMID: 33144427; PMCID: PMC7811621.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    76. Co-implantation of Tumor and Extensive Surrounding Tissue Improved the Establishment Rate of Surgical Specimens of Human-Patient Cancer in Nude Mice: Toward the Goal of Universal Individualized Cancer Therapy. In Vivo. 2020 Nov-Dec; 34(6):3241-3245. Murata T, Hozumi C, Hiroshima Y, Shimoya K, Hongo A, Inubushi S, Tanino H, Hoffman RM. PMID: 33144429; PMCID: PMC7811650.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    77. Ischemia reperfusion-induced metastasis is resistant to PPARγ agonist pioglitazone in a murine model of colon cancer. Sci Rep. 2020 10 29; 10(1):18565. Tashiro Y, Nishino H, Higuchi T, Sugisawa N, Fukuda Y, Yamamoto J, Inubushi S, Aoki T, Murakami M, Singh SR, Bouvet M, Hoffman RM. PMID: 33122687; PMCID: PMC7596558.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    78. Histone methylation status of H3K4me3 and H3K9me3 under methionine restriction is unstable in methionine-addicted cancer cells, but stable in normal cells. Biochem Biophys Res Commun. 2020 12 17; 533(4):1034-1038. Yamamoto J, Han Q, Inubushi S, Sugisawa N, Hamada K, Nishino H, Miyake K, Kumamoto T, Matsuyama R, Bouvet M, Endo I, Hoffman RM. PMID: 33019978.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    79. Prostate Cancer Metastases Are Strongly Inhibited by Agonistic Epha2 Ligands in an Orthotopic Mouse Model. Cancers (Basel). 2020 Oct 02; 12(10). Salem AF, Gambini L, Billet S, Sun Y, Oshiro H, Zhao M, Hoffman RM, Bhowmick NA, Pellecchia M. PMID: 33023262; PMCID: PMC7600344.
      View in: PubMed   Mentions: 1  
    80. A Gemcitabine Plus 5-Fluorouracil Combination Inhibits Gastric-Cancer Liver Metastasis in a PDOX Model: A Novel Treatment Strategy. Anticancer Res. 2020 Oct; 40(10):5393-5397. Sugisawa N, Nishino H, Higuchi T, Park JH, Yamamoto J, Tashiro Y, Kawaguchi K, Bouvet M, Unno M, Hoffman RM. PMID: 32988858.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    81. Fluorescence-guided hepatobiliary surgery with long and short wavelength fluorophores. Hepatobiliary Surg Nutr. 2020 Oct; 9(5):615-639. Lwin TM, Hoffman RM, Bouvet M. PMID: 33163512; PMCID: PMC7603922.
      View in: PubMed   Mentions: 2  
    82. FUCCI Real-Time Cell-Cycle Imaging as a Guide for Designing Improved Cancer Therapy: A Review of Innovative Strategies to Target Quiescent Chemo-Resistant Cancer Cells. Cancers (Basel). 2020 Sep 17; 12(9). Yano S, Tazawa H, Kagawa S, Fujiwara T, Hoffman RM. PMID: 32957652; PMCID: PMC7563319.
      View in: PubMed   Mentions: 4  
    83. Indocyanine Green Labels an Orthotopic Nude-Mouse Model of Very-Early Colon-Cancer Liver Metastases. In Vivo. 2020 Sep-Oct; 34(5):2277-2280. Tashiro Y, Hollandsworth HM, Nishino H, Yamamoto J, Amirfakhri S, Filemoni F, Sugisawa N, Aoki T, Murakami M, Hoffman RM, Bouvet M. PMID: 32871750; PMCID: PMC7652533.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    84. Oral Methioninase Inhibits Recurrence in a PDOX Mouse Model of Aggressive Triple-negative Breast Cancer. In Vivo. 2020 Sep-Oct; 34(5):2281-2286. Lim HI, Hamada K, Yamamoto J, Han Q, Tan Y, Choi HJ, Nam SJ, Bouvet M, Hoffman RM. PMID: 32871751; PMCID: PMC7652477.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    85. Humanized Fluorescent Tumor-associated Glycoprotein-72 Antibody Selectively Labels Colon-cancer Liver Metastases in Orthotopic Mouse Models. In Vivo. 2020 Sep-Oct; 34(5):2303-2307. Hollandsworth HM, Nishino H, Turner M, Amirfakhri S, Filemoni F, Hoffman RM, Yazaki PJ, Bouvet M. PMID: 32871754; PMCID: PMC7652487.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    86. An Improved Encapsulation Method for Cryopreserving Hepatocytes for Functional Transplantation Using a Thermo-reversible Gelation Polymer. In Vivo. 2020 Sep-Oct; 34(5):2309-2316. Yamada K, Aoki T, Enami Y, Tashiro Y, Zehaou Z, Koizumi T, Kusano T, Matsuda K, Wada Y, Shibata H, Tomioka K, Siriratsivawong K, Hoffman RM, Murakami M. PMID: 32871755; PMCID: PMC7652459.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    87. Adjuvant Oral Recombinant Methioninase Inhibits Lung Metastasis in a Surgical Breast-Cancer Orthotopic Syngeneic Model. Anticancer Res. 2020 Sep; 40(9):4869-4874. Sugisawa N, Hamada K, Han Q, Yamamoto J, Sun YU, Nishino H, Kawaguchi K, Bouvet M, Unno M, Hoffman RM. PMID: 32878774.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    88. Brucea javanica Increases Survival and Enhances Gemcitabine Efficacy in a Patient-derived Orthotopic Xenograft (PDOX) Mouse Model of Pancreatic Cancer. Anticancer Res. 2020 Sep; 40(9):4969-4978. Yang H, Tong Z, Shen L, Sun YU, Hoffman RM, Huang J. PMID: 32878785.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    89. Fluorophore-conjugated Helicobacter pylori recombinant membrane protein (HopQ) labels primary colon cancer and metastases in orthotopic mouse models by binding CEA-related cell adhesion molecules. Transl Oncol. 2020 Dec; 13(12):100857. Hollandsworth HM, Schmitt V, Amirfakhri S, Filemoni F, Schmidt A, Landström M, Lyndin M, Backert S, Gerhard M, Wennemuth G, Hoffman RM, Singer BB, Bouvet M. PMID: 32866936; PMCID: PMC7475271.
      View in: PubMed   Mentions:
    90. Oral recombinant methioninase increases TRAIL receptor-2 expression to regress pancreatic cancer in combination with agonist tigatuzumab in an orthotopic mouse model. Cancer Lett. 2020 11 01; 492:174-184. Yamamoto J, Miyake K, Han Q, Tan Y, Inubushi S, Sugisawa N, Higuchi T, Tashiro Y, Nishino H, Homma Y, Matsuyama R, Chawla SP, Bouvet M, Singh SR, Endo I, Hoffman RM. PMID: 32739322.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    91. The identification of candidate effective combination regimens for pancreatic cancer using the histoculture drug response assay. Sci Rep. 2020 07 20; 10(1):12004. Jun E, Park Y, Lee W, Kwon J, Lee S, Kim MB, Lee JS, Song KB, Hwang DW, Lee JH, Hoffman RM, Kim SC. PMID: 32686712; PMCID: PMC7371642.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    92. NEDD8-conjugating enzyme UBC12 as a novel therapeutic target in esophageal squamous cell carcinoma. Signal Transduct Target Ther. 2020 07 10; 5(1):123. Wang S, Xian J, Li L, Jiang Y, Liu Y, Cai L, Hoffman RM, Jia L, Zhao H, Zhang Y. PMID: 32651357; PMCID: PMC7351728.
      View in: PubMed   Mentions: 2  Translation:Humans
    93. Osimertinib regressed an EGFR-mutant lung-adenocarcinoma bone-metastasis mouse model and increased long-term survival. Transl Oncol. 2020 Oct; 13(10):100826. Higuchi T, Sugisawa N, Park JH, Sun Y, Zhu G, Yamamoto N, Hayashi K, Kimura H, Miwa S, Igarashi K, Bouvet M, Singh SR, Tsuchiya H, Hoffman RM. PMID: 32659740; PMCID: PMC7356269.
      View in: PubMed   Mentions: 1  
    94. Eribulin Regresses a Doxorubicin-resistant Dedifferentiated Liposarcoma in a Patient-derived Orthotopic Xenograft Mouse Model. Cancer Genomics Proteomics. 2020 Jul-Aug; 17(4):351-358. Igarashi K, Kawaguchi K, Kiyuna T, Miyake K, Higuchi T, Yamamoto N, Hayashi K, Kimura H, Miwa S, Singh SR, Tsuchiya H, Hoffman RM. PMID: 32576580; PMCID: PMC7367606.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    95. Pathological Validity of Using Near-infrared Fluorescence Imaging for Securing Surgical Margins During Liver Resection. Anticancer Res. 2020 Jul; 40(7):3873-3882. Tashiro Y, Aoki T, Hirai T, Koizumi T, Mansou DA, Kusano T, Matsuda K, Yamada K, Nogaki K, Hakozaki T, Wada Y, Shibata H, Tomioka K, Yamazaki T, Saito K, Fujimori A, Enami Y, Hoffman RM, Murakami M. PMID: 32620627.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    96. Near-infrared photoimmunotherapy is effective treatment for colorectal cancer in orthotopic nude-mouse models. PLoS One. 2020; 15(6):e0234643. Hollandsworth HM, Amirfakhri S, Filemoni F, Molnar J, Hoffman RM, Yazaki P, Bouvet M. PMID: 32555717; PMCID: PMC7302706.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    97. Oral Methioninase for Covid-19 Methionine-restriction Therapy. In Vivo. 2020 Jun; 34(3 Suppl):1593-1596. Hoffman RM, Han Q. PMID: 32503816; PMCID: PMC8378026.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCellsPHPublic Health
    98. Oncogenic miRNAs Identified in Tear Exosomes From Metastatic Breast Cancer Patients. Anticancer Res. 2020 06; 40(6):3091-3096. Inubushi S, Kawaguchi H, Mizumoto S, Kunihisa T, Baba M, Kitayama Y, Takeuchi T, Hoffman RM, Sasaki R. PMID: 32487603.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    99. The future of tumour-specific fluorescence-guided surgery for pancreatic cancer. Lancet Gastroenterol Hepatol. 2020 08; 5(8):715-717. Lwin TM, Hoffman RM, Bouvet M. PMID: 32416765.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    100. Myc is a prognostic biomarker and potential therapeutic target in osteosarcoma. Ther Adv Med Oncol. 2020; 12:1758835920922055. Feng W, Dean DC, Hornicek FJ, Spentzos D, Hoffman RM, Shi H, Duan Z. PMID: 32426053; PMCID: PMC7222246.
      View in: PubMed   Mentions: 9  
    101. Tumor-specific near-infrared nanobody probe rapidly labels tumors in an orthotopic mouse model of pancreatic cancer. Surgery. 2020 07; 168(1):85-91. Lwin TM, Hernot S, Hollandsworth H, Amirfakhri S, Filemoni F, Debie P, Hoffman RM, Bouvet M. PMID: 32370916; PMCID: PMC7311276.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    102. Eribulin Regresses a Cisplatinum-resistant Rare-type Triple-negative Matrix-producing Breast Carcinoma Patient-derived Orthotopic Xenograft Mouse Model. Anticancer Res. 2020 May; 40(5):2475-2479. Yamamoto J, Murata T, Sugisawa N, Higuchi T, Tashiro Y, Nishino H, Inubushi S, Sun YU, Lim H, Miyake K, Shimoya K, Nomura T, Kurebayashi J, Tanino H, Hozumi C, Bouvet M, Singh SR, Endo I, Hoffman RM. PMID: 32366391.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    103. A Single Low Dose of Eribulin Regressed a Highly Aggressive Triple-negative Breast Cancer in a Patient-derived Orthotopic Xenograft Model. Anticancer Res. 2020 May; 40(5):2481-2485. Lim HI, Yamamoto J, Inubushi S, Nishino H, Tashiro Y, Sugisawa N, Han Q, Sun YU, Choi HJ, Nam SJ, Kim MB, Lee JS, Hozumi C, Bouvet M, Singh SR, Hoffman RM. PMID: 32366392.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    104. A Triple-negative Matrix-producing Breast Carcinoma Patient-derived Orthotopic Xenograft (PDOX) Mouse Model Is Sensitive to Bevacizumab and Vinorelbine, Regressed by Eribulin and Resistant to Olaparib. Anticancer Res. 2020 May; 40(5):2509-2514. Yamamoto J, Murata T, Tashiro Y, Higuchi T, Sugisawa N, Nishino H, Inubushi S, Sun YU, Lim H, Miyake K, Hongo A, Nomura T, Saitoh W, Moriya T, Tanino H, Hozumi C, Bouvet M, Singh SR, Endo I, Hoffman RM. PMID: 32366395.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    105. Recombinant Methioninase Combined With Tumor-targeting Salmonella typhimurium A1-R Induced Regression in a PDOX Mouse Model of Doxorubicin-resistant Dedifferentiated Liposarcoma. Anticancer Res. 2020 May; 40(5):2515-2523. Igarashi K, Kawaguchi K, Zhao M, Han Q, Tan Y, Kiyuna T, Miyake K, Higuchi T, Nelson SD, Dry SM, Li Y, Yamamoto N, Hayashi K, Kimura H, Miwa S, Singh SR, Tsuchiya H, Hoffman RM. PMID: 32366396.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    106. Oral dosing of Recombinant Methioninase Is Associated With a 70% Drop in PSA in a Patient With Bone-metastatic Prostate Cancer and 50% Reduction in Circulating Methionine in a High-stage Ovarian Cancer Patient. Anticancer Res. 2020 May; 40(5):2813-2819. Han Q, Tan Y, Hoffman RM. PMID: 32366428.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimals
    107. Oral Recombinant Methioninase Inhibits Diabetes Onset in Mice on a High-fat Diet. In Vivo. 2020 May-Jun; 34(3):973-978. Tashiro Y, Han Q, Tan Y, Sugisawa N, Yamamoto J, Nishino H, Inubushi S, Sun YU, Zhu G, Lim H, Aoki T, Murakami M, Bouvet M, Hoffman RM. PMID: 32354882; PMCID: PMC7279799.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    108. Oral Recombinant Methioninase Prevents Nonalcoholic Fatty Liver Disease in Mice on a High Fat Diet. In Vivo. 2020 May-Jun; 34(3):979-984. Tashiro Y, Han Q, Tan Y, Sugisawa N, Yamamoto J, Nishino H, Inubushi S, Sun YU, Lim H, Aoki T, Murakami M, Takahashi Y, Bouvet M, Hoffman RM. PMID: 32354883; PMCID: PMC7279815.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    109. Comparison of the Efficacy of EGFR Tyrosine Kinase Inhibitors Erlotinib and Low-dose Osimertinib on a PC-9-GFP EGFR Mutant Non-small-cell Lung Cancer Growing in the Brain of Nude Mice. In Vivo. 2020 May-Jun; 34(3):1027-1030. Katsuya Y, Miyake K, Higuchi T, Oshiro H, Sugisawa N, Singh SR, Goto Y, Zhao M, Hoffman RM. PMID: 32354888; PMCID: PMC7279826.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    110. A Novel Anionic-phosphate-platinum Complex Effectively Targets a Cisplatinum-resistant Osteosarcoma in a Patient-derived Orthotopic Xenograft Mouse Model. Cancer Genomics Proteomics. 2020 May-Jun; 17(3):217-223. Igarashi K, Kawaguchi K, Yamamoto N, Hayashi K, Kimura H, Miwa S, Higuchi T, Taniguchi Y, Yonezawa H, Araki Y, Morinaga S, Misra S, Nelson SD, Dry SM, Li Y, Odani A, Singh SR, Tsuchiya H, Hoffman RM. PMID: 32345663; PMCID: PMC7259888.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    111. Humanized Anti-Tumor-Associated Glycoprotein-72 for Submillimeter Near-Infrared Detection of Colon Cancer in Metastatic Mouse Models. J Surg Res. 2020 08; 252:16-21. Hollandsworth HM, Amirfakhri S, Filemoni F, Hoffman RM, Molnar J, Yazaki PJ, Bouvet M. PMID: 32217350; PMCID: PMC7295682.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    112. Temozolomide and Pazopanib Combined with FOLFOX Regressed a Primary Colorectal Cancer in a Patient-derived Orthotopic Xenograft Mouse Model. Transl Oncol. 2020 Mar; 13(3):100739. Zhu G, Zhao M, Han Q, Tan Y, Sun Y, Bouvet M, Clary B, Singh SR, Ye J, Hoffman RM. PMID: 32143177; PMCID: PMC7058405.
      View in: PubMed   Mentions:
    113. Oral Recombinant Methioninase Prevents Obesity in Mice on a High-fat Diet. In Vivo. 2020 Mar-Apr; 34(2):489-494. Tashiro Y, Han Q, Tan Y, Sugisawa N, Yamamoto J, Nishino H, Inubushi S, Higuchi T, Aoki T, Murakami M, Hoffman RM. PMID: 32111745; PMCID: PMC7157881.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    114. Pazopanib Inhibits Tumor Growth, Lymph-node Metastasis and Lymphangiogenesis of an Orthotopic Mouse of Colorectal Cancer. Cancer Genomics Proteomics. 2020 Mar-Apr; 17(2):131-139. Zhu G, Zhao M, Han Q, Tan Y, Sun YU, Bouvet M, Singh SR, Ye J, Hoffman RM. PMID: 32108035; PMCID: PMC7078832.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    115. APELA/ELA32 Reduces Iodixanol-induced Apoptosis, Inflammatory Response and Mitochondrial and DNA Damage in Renal Tubular Epithelial Cells. Anticancer Res. 2020 Feb; 40(2):635-643. Li Y, Huang J, He S, Lu Z, Zhang J, Li X, Yang Z, Hoffman RM, Wu Q. PMID: 32014904.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    116. Anti-carcinoembryonic antigen-related cell adhesion molecule antibody for fluorescence visualization of primary colon cancer and metastases in patient-derived orthotopic xenograft mouse models. Oncotarget. 2020 Jan 28; 11(4):429-439. Hollandsworth HM, Amirfakhri S, Filemoni F, Schmitt V, Wennemuth G, Schmidt A, Hoffman RM, Singer BB, Bouvet M. PMID: 32064046; PMCID: PMC6996915.
      View in: PubMed   Mentions: 7     Fields:    
    117. Effective targeting of the ubiquitin-like modifier NEDD8 for lung adenocarcinoma treatment. Cell Biol Toxicol. 2020 08; 36(4):349-364. Jiang Y, Cheng W, Li L, Zhou L, Liang Y, Zhang W, Chen W, Wang S, Zhao H, Chen G, Zhou W, Ji G, Zhang Y, Hoffman RM, Wang M, Jia L. PMID: 31907687.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    118. Collective cancer invasion forms an integrin-dependent radioresistant niche. J Exp Med. 2020 01 06; 217(1). Haeger A, Alexander S, Vullings M, Kaiser FMP, Veelken C, Flucke U, Koehl GE, Hirschberg M, Flentje M, Hoffman RM, Geissler EK, Kissler S, Friedl P. PMID: 31658985; PMCID: PMC7037234.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    119. TRAF6-Mediated Inflammatory Cytokines Secretion in LPS-induced Colorectal Cancer Cells Is Regulated by miR-140. Cancer Genomics Proteomics. 2020 Jan-Feb; 17(1):23-33. Zhu G, Lin C, Cheng Z, Wang Q, Hoffman RM, Singh SR, Huang Y, Zheng W, Yang S, Ye J. PMID: 31882548; PMCID: PMC6937127.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    120. PPARγ Agonist Pioglitazone in Combination With Cisplatinum Arrests a Chemotherapy-resistant Osteosarcoma PDOX Model. Cancer Genomics Proteomics. 2020 Jan-Feb; 17(1):35-40. Higuchi T, Yamamoto J, Sugisawa N, Tashiro Y, Nishino H, Yamamoto N, Hayashi K, Kimura H, Miwa S, Igarashi K, Bouvet M, Singh SR, Tsuchiya H, Hoffman RM. PMID: 31882549; PMCID: PMC6937125.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    121. Relevance of Vitamin D in Melanoma Development, Progression and Therapy. Anticancer Res. 2020 Jan; 40(1):473-489. Brozyna AA, Hoffman RM, Slominski AT. PMID: 31892603; PMCID: PMC6948187.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    122. Exquisite Tumor Targeting by Salmonella A1-R in Combination with Caffeine and Valproic Acid Regresses an Adult Pleomorphic Rhabdomyosarcoma Patient-Derived Orthotopic Xenograft Mouse Model. Transl Oncol. 2020 Feb; 13(2):393-400. Igarashi K, Kawaguchi K, Zhao M, Kiyuna T, Miyake K, Miyake M, Nelson SD, Dry SM, Li Y, Yamamoto N, Hayashi K, Kimura H, Miwa S, Higuchi T, Singh SR, Tsuchiya H, Hoffman RM. PMID: 31896528; PMCID: PMC6940643.
      View in: PubMed   Mentions: 3  
    123. Combination of oral recombinant methioninase and decitabine arrests a chemotherapy-resistant undifferentiated soft-tissue sarcoma patient-derived orthotopic xenograft mouse model. Biochem Biophys Res Commun. 2020 02 26; 523(1):135-139. Higuchi T, Han Q, Miyake K, Oshiro H, Sugisawa N, Tan Y, Yamamoto N, Hayashi K, Kimura H, Miwa S, Igarashi K, Bouvet M, Singh SR, Tsuchiya H, Hoffman RM. PMID: 31839218.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    124. Combination of Trabectedin With Irinotecan, Leucovorin and 5-Fluorouracil Arrests Primary Colorectal Cancer in an Imageable Patient-derived Orthotopic Xenograft Mouse Model. Anticancer Res. 2019 Dec; 39(12):6463-6470. Zhu G, Zhao M, Han Q, Tan Y, Sun YU, Bouvet M, Clary B, Singh SR, Ye J, Hoffman RM. PMID: 31810910.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    125. The combination of oral-recombinant methioninase and azacitidine arrests a chemotherapy-resistant osteosarcoma patient-derived orthotopic xenograft mouse model. Cancer Chemother Pharmacol. 2020 02; 85(2):285-291. Higuchi T, Sugisawa N, Yamamoto J, Oshiro H, Han Q, Yamamoto N, Hayashi K, Kimura H, Miwa S, Igarashi K, Tan Y, Kuchipudi S, Bouvet M, Singh SR, Tsuchiya H, Hoffman RM. PMID: 31705268.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimals
    126. Double-negative T Cells Inhibit Proliferation and Invasion of Human Pancreatic Cancer Cells in Co-culture. Anticancer Res. 2019 Nov; 39(11):5911-5918. Lu Y, Hu P, Zhou H, Yang Z, Sun YU, Hoffman RM, Chen J. PMID: 31704815.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    127. Robo1-specific CAR-NK Immunotherapy Enhances Efficacy of 125I Seed Brachytherapy in an Orthotopic Mouse Model of Human Pancreatic Carcinoma. Anticancer Res. 2019 Nov; 39(11):5919-5925. Xia N, Haopeng P, Gong JU, Lu J, Chen Z, Zheng Y, Wang Z, Sun YU, Yang Z, Hoffman RM, Liu F. PMID: 31704816.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    128. Aurora-A/NF-ĸB Signaling Is Associated With Radio-resistance in Human Lung Adenocarcinoma. Anticancer Res. 2019 Nov; 39(11):5991-5998. Liu JB, Hu L, Yang Z, Sun YU, Hoffman RM, Yi Z. PMID: 31704824.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    129. Combination of Trabectedin With Oxaliplatinum and 5-Fluorouracil Arrests a Primary Colorectal Cancer in a Patient-derived Orthotopic Xenograft Mouse Model. Anticancer Res. 2019 Nov; 39(11):5999-6005. Zhu G, Zhao M, Han Q, Tan Y, Sun YU, Bouvet M, Singh SR, Ye J, Hoffman RM. PMID: 31704825.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    130. MyD88 Regulates LPS-induced NF-ĸB/MAPK Cytokines and Promotes Inflammation and Malignancy in Colorectal Cancer Cells. Cancer Genomics Proteomics. 2019 Nov-Dec; 16(6):409-419. Zhu G, Cheng Z, Lin C, Hoffman RM, Huang Y, Singh SR, Zheng W, Yang S, Ye J. PMID: 31659096; PMCID: PMC6885359.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    131. Novel targets identified by integrated cancer-stromal interactome analysis of pancreatic adenocarcinoma. Cancer Lett. 2020 01 28; 469:217-227. Hiroshima Y, Kasajima R, Kimura Y, Komura D, Ishikawa S, Ichikawa Y, Bouvet M, Yamamoto N, Oshima T, Morinaga S, Singh SR, Hoffman RM, Endo I, Miyagi Y. PMID: 31669204.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    132. Patient-derived orthotopic xenograft models of sarcoma. Cancer Lett. 2020 01 28; 469:332-339. Igarashi K, Kawaguchi K, Murakami T, Miyake K, Kiyuna T, Miyake M, Hiroshima Y, Higuchi T, Oshiro H, Nelson SD, Dry SM, Li Y, Yamamoto N, Hayashi K, Kimura H, Miwa S, Singh SR, Tsuchiya H, Hoffman RM. PMID: 31639427.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    133. Induction of Metastasis by Low-dose Gemcitabine in a Pancreatic Cancer Orthotopic Mouse Model: An Opposite Effect of Chemotherapy. Anticancer Res. 2019 Oct; 39(10):5339-5344. Sugisawa N, Miyake K, Higuchi T, Oshiro H, Zhang Z, Park JH, Kawaguchi K, Chawla SP, Bouvet M, Singh SR, Unno M, Hoffman RM. PMID: 31570427.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    134. Oral recombinant methioninase combined with oxaliplatinum and 5-fluorouracil regressed a colon cancer growing on the peritoneal surface in a patient-derived orthotopic xenograft mouse model. Tissue Cell. 2019 Dec; 61:109-114. Park JH, Han Q, Zhao M, Tan Y, Higuchi T, Yoon SN, Sugisawa N, Yamamoto J, Bouvet M, Clary B, Singh SR, Hoffman RM. PMID: 31759402.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    135. AMMECR1 Inhibits Apoptosis and Promotes Cell-cycle Progression and Proliferation of the A549 Human Lung Cancer Cell Line. Anticancer Res. 2019 Sep; 39(9):4637-4642. Ge H, Cheng N, Xu X, Yang Z, Hoffman RM, Zhu J. PMID: 31519561.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    136. Oral Recombinant Methioninase, Combined With Oral Caffeine and Injected Cisplatinum, Overcome Cisplatinum-Resistance and Regresses Patient-derived Orthotopic Xenograft Model of Osteosarcoma. Anticancer Res. 2019 Sep; 39(9):4653-4657. Higuchi T, Oshiro H, Miyake K, Sugisawa N, Han Q, Tan Y, Park J, Zhang Z, Razmjooei S, Yamamoto N, Hayashi K, Kimura H, Miwa S, Igarashi K, Bouvet M, Chawla SP, Singh SR, Tsuchiya H, Hoffman RM. PMID: 31519563.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimals
    137. Oral Recombinant Methioninase Overcomes Colorectal-cancer Liver Metastasis Resistance to the Combination of 5-Fluorouracil and Oxaliplatinum in a Patient-derived Orthotopic Xenograft Mouse Model. Anticancer Res. 2019 Sep; 39(9):4667-4671. Oshiro H, Tome Y, Kiyuna T, Yoon SN, Lwin TM, Han Q, Tan Y, Miyake K, Higuchi T, Sugisawa N, Katsuya Y, Park JH, Zang Z, Razmjooei S, Bouvet M, Clary B, Singh SR, Kanaya F, Nishida K, Hoffman RM. PMID: 31519565.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimals
    138. Eribulin Suppressed Cisplatinum- and Doxorubicin-resistant Recurrent Lung Metastatic Osteosarcoma in a Patient-derived Orthotopic Xenograft Mouse Model. Anticancer Res. 2019 Sep; 39(9):4775-4779. Kiyuna T, Tome Y, Miyake K, Murakami T, Oshiro H, Igarashi K, Kawaguchi K, Hsu J, Singh M, Li Y, Nelson S, Bouvet M, Singh SR, Kanaya F, Hoffman RM. PMID: 31519578.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    139. Combination Treatment With Sorafenib and Everolimus Regresses a Doxorubicin-resistant Osteosarcoma in a PDOX Mouse Model. Anticancer Res. 2019 Sep; 39(9):4781-4786. Higuchi T, Sugisawa N, Miyake K, Oshiro H, Yamamoto N, Hayashi K, Kimura H, Miwa S, Igarashi K, Kline Z, Belt P, Chawla SP, Bouvet M, Singh SR, Tsuchiya H, Hoffman RM. PMID: 31519579.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimals
    140. Pioglitazone, an agonist of PPARγ, reverses doxorubicin-resistance in an osteosarcoma patient-derived orthotopic xenograft model by downregulating P-glycoprotein expression. Biomed Pharmacother. 2019 Oct; 118:109356. Higuchi T, Sugisawa N, Miyake K, Oshiro H, Yamamoto N, Hayashi K, Kimura H, Miwa S, Igarashi K, Kline Z, Bouvet M, Singh SR, Tsuchiya H, Hoffman RM. PMID: 31545293.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    141. Efficacy of oral recombinant methioninase combined with oxaliplatinum and 5-fluorouracil on primary colon cancer in a patient-derived orthotopic xenograft mouse model. Biochem Biophys Res Commun. 2019 10 15; 518(2):306-310. Park JH, Zhao M, Han Q, Sun Y, Higuchi T, Sugisawa N, Yamamoto J, Singh SR, Clary B, Bouvet M, Hoffman RM. PMID: 31421825.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    142. High-Mobility Group Box 1 expression predicts survival of patients after resection of adenocarcinoma of the ampulla of Vater. World J Surg Oncol. 2019 Aug 09; 17(1):140. Murakami T, Matsuyama R, Ueda M, Mochizuki Y, Homma Y, Kameda K, Yazawa K, Izumisawa Y, Fukushima T, Kamimukai N, Yoshida K, Kamiya N, Hoffman RM, Endo I. PMID: 31399104; PMCID: PMC6689175.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    143. Color-coded Imaging of the Fate of Cancer-cell-derived Exosomes During Pancreatic Cancer Metastases in a Nude-mouse Model. Anticancer Res. 2019 Aug; 39(8):4055-4060. Satake T, Suetsugu A, Nakamura M, Kunisada T, Saji S, Moriwaki H, Shimizu M, Hoffman RM. PMID: 31366487.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    144. Choline-deficient-diet Decreases Fibroblasts in the Circulating Tumor Cell (CTC) Microenvironment. Anticancer Res. 2019 Aug; 39(8):4061-4064. Matsuura K, Suetsugu A, Satake T, Nakamura M, Kunisada T, Shimizu M, Hoffman RM. PMID: 31366488.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    145. Tumor-sealing Surgical Orthotopic Implantation of Human Colon Cancer in Nude Mice Induces Clinically-relevant Metastases Without Early Peritoneal Carcinomatosis. Anticancer Res. 2019 Aug; 39(8):4065-4071. Yoon SN, Park JH, Lwin TM, Miyake K, Singh SR, Hoffman RM, Bouvet M. PMID: 31366489.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    146. Sorafenib and Palbociclib Combination Regresses a Cisplatinum-resistant Osteosarcoma in a PDOX Mouse Model. Anticancer Res. 2019 Aug; 39(8):4079-4084. Higuchi T, Sugisawa N, Miyake K, Oshiro H, Yamamoto N, Hayashi K, Kimura H, Miwa S, Igarashi K, Chawla SP, Bouvet M, Singh SR, Tsuchiya H, Hoffman RM. PMID: 31366491.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    147. The Combination of Olaratumab with Doxorubicin and Cisplatinum Regresses a Chemotherapy-Resistant Osteosarcoma in a Patient-Derived Orthotopic Xenograft Mouse Model. Transl Oncol. 2019 Sep; 12(9):1257-1263. Higuchi T, Sugisawa N, Miyake K, Oshiro H, Yamamoto N, Hayashi K, Kimura H, Miwa S, Igarashi K, Bouvet M, Singh SR, Tsuchiya H, Hoffman RM. PMID: 31299622; PMCID: PMC6624322.
      View in: PubMed   Mentions: 2  
    148. RE: "Intraoperative Near-infrared Imaging Can Identify Neoplasms and Aid in Real-time Margin Assessment During Pancreatic Resection". Ann Surg. 2019 07; 270(1):21-22. Bouvet M, Lwin TM, Hoffman RM. PMID: 31188174.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    149. Peritoneal Metastases in a Patient-derived Orthotopic Xenograft (PDOX) Model of Colon Cancer Imaged Non-invasively via Red Fluorescent Protein Labeled Stromal Cells. Anticancer Res. 2019 Jul; 39(7):3463-3467. Park JH, Zhao M, Oshiro H, Miyake K, Higuchi T, Reynoso J, Razmjooei S, Bouvet M, Clary B, Zhang Z, Sugisawa N, Yamamoto J, Singh SR, Hoffman RM. PMID: 31262870.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    150. Hair-follicle-associated pluripotent stem cells derived from cryopreserved intact human hair follicles sustain multilineage differentiation potential. Sci Rep. 2019 06 27; 9(1):9326. Obara K, Tohgi N, Mii S, Hamada Y, Arakawa N, Aki R, Singh SR, Hoffman RM, Amoh Y. PMID: 31249324; PMCID: PMC6597789.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    151. Promotion of tumor-associated macrophages infiltration by elevated neddylation pathway via NF-κB-CCL2 signaling in lung cancer. Oncogene. 2019 07; 38(29):5792-5804. Zhou L, Jiang Y, Liu X, Li L, Yang X, Dong C, Liu X, Lin Y, Li Y, Yu J, He R, Huang S, Liu G, Zhang Y, Jeong LS, Hoffman RM, Jia L. PMID: 31243299.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    152. Expression of anti-aging type-XVII collagen (COL17A1/BP180) in hair follicle-associated pluripotent (HAP) stem cells during differentiation. Tissue Cell. 2019 Aug; 59:33-38. Shirai K, Obara K, Tohgi N, Yamazaki A, Aki R, Hamada Y, Arakawa N, Singh SR, Hoffman RM, Amoh Y. PMID: 31383286.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    153. Efficacy of Tumor-Targeting Salmonella typhimurium A1-R against Malignancies in Patient-Derived Orthotopic Xenograft (PDOX) Murine Models. Cells. 2019 06 16; 8(6). Murakami T, Hiroshima Y, Miyake K, Kiyuna T, Endo I, Zhao M, Hoffman RM. PMID: 31208120; PMCID: PMC6628209.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    154. The combination of gemcitabine and docetaxel arrests a doxorubicin-resistant dedifferentiated liposarcoma in a patient-derived orthotopic xenograft model. Biomed Pharmacother. 2019 Sep; 117:109093. Miyake K, Higuchi T, Oshiro H, Zhang Z, Sugisawa N, Park JH, Razmjooei S, Katsuya Y, Barangi M, Li Y, Nelson SD, Murakami T, Homma Y, Hiroshima Y, Matsuyama R, Bouvet M, Chawla SP, Singh SR, Endo I, Hoffman RM. PMID: 31200257.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    155. Improved antibody-guided surgery with a near-infrared dye on a pegylated linker for CEA-positive tumors. J Biomed Opt. 2019 06; 24(6):1-9. Yazaki P, Lwin T, Minnix M, Li L, Sherman A, Molnar J, Miller A, Frankel P, Chea J, Poku E, Bowles N, Hoffman R, Shively J, Bouvet M. PMID: 31254333; PMCID: PMC6978469.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    156. Knockdown of Histone Methyltransferase WHSC1 Induces Apoptosis and Inhibits Cell Proliferation and Tumorigenesis in Salivary Adenoid Cystic Carcinoma. Anticancer Res. 2019 Jun; 39(6):2729-2737. Liu C, Jiang YH, Zhao ZL, Wu HW, Zhang L, Yang Z, Hoffman RM, Zheng JW. PMID: 31177108.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    157. Traditional Chinese Medicine (TCM) Astragalus Membranaceus and Curcuma Wenyujin Promote Vascular Normalization in Tumor-derived Endothelial Cells of Human Hepatocellular Carcinoma. Anticancer Res. 2019 Jun; 39(6):2739-2747. Zang W, Bian H, Huang X, Yin G, Zhang C, Han LI, Hao P, Ding S, Sun YU, Yang Z, Hoffman RM, Tang D. PMID: 31177109.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    158. Cyt-Geist: Current and Future Challenges in Cytometry: Reports of the CYTO 2018 Conference Workshops. Cytometry A. 2019 06; 95(6):598-644. Czechowska K, Lannigan J, Wang L, Arcidiacono J, Ashhurst TM, Barnard RM, Bauer S, Bispo C, Bonilla DL, Brinkman RR, Cabanski M, Chang HD, Chakrabarti L, Chojnowski G, Cotleur B, Degheidy H, Dela Cruz GV, Eck S, Elliott J, Errington R, Filby A, Gagnon D, Gardner R, Green C, Gregory M, Groves CJ, Hall C, Hammes F, Hedrick M, Hoffman R, Icha J, Ivaska J, Jenner DC, Jones D, Kerckhof FM, Kukat C, Lanham D, Leavesley S, Lee M, Lin-Gibson S, Litwin V, Liu Y, Molloy J, Moore JS, Müller S, Nedbal J, Niesner R, Nitta N, Ohlsson-Wilhelm B, Paul NE, Perfetto S, Portat Z, Props R, Radtke S, Rayanki R, Rieger A, Rogers S, Rubbens P, Salomon R, Schiemann M, Sharpe J, Sonder SU, Stewart JJ, Sun Y, Ulrich H, Van Isterdael G, Vitaliti A, van Vreden C, Weber M, Zimmermann J, Vacca G, Wallace P, Tárnok A. PMID: 31207046.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    159. Targeting neddylation inhibits intravascular survival and extravasation of cancer cells to prevent lung-cancer metastasis. Cell Biol Toxicol. 2019 06; 35(3):233-245. Jiang Y, Liang Y, Li L, Zhou L, Cheng W, Yang X, Yang X, Qi H, Yu J, Jeong LS, Hoffman RM, Zheng P, Jia L. PMID: 31140025.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    160. Anti-Claudin-1 Conjugated to a Near-Infrared Fluorophore Targets Colon Cancer in PDOX Mouse Models. J Surg Res. 2019 10; 242:145-150. Hollandsworth HM, Lwin TM, Amirfakhri S, Filemoni F, Batra SK, Hoffman RM, Dhawan P, Bouvet M. PMID: 31077946; PMCID: PMC7144806.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    161. Pazopanib regresses a doxorubicin-resistant synovial sarcoma in a patient-derived orthotopic xenograft mouse model. Tissue Cell. 2019 Jun; 58:107-111. Igarashi K, Kawaguchi K, Kiyuna T, Miyake K, Miyake M, Nelson SD, Russell TA, Dry SM, Li Y, Yamamoto N, Hayashi K, Kimura H, Miwa S, Higuchi T, Singh SR, Tsuchiya H, Hoffman RM. PMID: 31133237.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    162. Efficacy of Recombinant Methioninase (rMETase) on Recalcitrant Cancer Patient-Derived Orthotopic Xenograft (PDOX) Mouse Models: A Review. Cells. 2019 05 02; 8(5). Kawaguchi K, Han Q, Li S, Tan Y, Igarashi K, Murakami T, Unno M, Hoffman RM. PMID: 31052611; PMCID: PMC6562625.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimals
    163. Tumor-targeting Salmonella typhimurium A1-R overcomes nab-paclitaxel resistance in a cervical cancer PDOX mouse model. Arch Gynecol Obstet. 2019 06; 299(6):1683-1690. Miyake K, Murata T, Murakami T, Zhao M, Kiyuna T, Kawaguchi K, Igarashi K, Miyake M, Lwin TM, Hozumi C, Komatsu S, Kikuchi T, Bouvet M, Shimoya K, Singh SR, Endo I, Hoffman RM. PMID: 30953192.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    164. Trabectedin and irinotecan combination regresses a cisplatinum-resistant osteosarcoma in a patient-derived orthotopic xenograft nude-mouse model. Biochem Biophys Res Commun. 2019 May 28; 513(2):326-331. Higuchi T, Miyake K, Oshiro H, Sugisawa N, Yamamoto N, Hayashi K, Kimura H, Miwa S, Igarashi K, Chawla SP, Bouvet M, Singh SR, Tsuchiya H, Hoffman RM. PMID: 30955860.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    165. Temozolomide targets and arrests a doxorubicin-resistant follicular dendritic-cell sarcoma patient-derived orthotopic xenograft mouse model. Tissue Cell. 2019 Jun; 58:17-23. Oshiro H, Tome Y, Kiyuna T, Miyake K, Kawaguchi K, Higuchi T, Miyake M, Zang Z, Razmjooei S, Barangi M, Wangsiricharoen S, Nelson SD, Li Y, Bouvet M, Singh SR, Kanaya F, Hoffman RM. PMID: 31133242.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    166. Chemo-resistant Gastric Cancer Associated Gene Expression Signature: Bioinformatics Analysis Based on Gene Expression Omnibus. Anticancer Res. 2019 Apr; 39(4):1689-1698. Liu JB, Jian T, Yue C, Chen D, Chen W, Bao TT, Liu HX, Cao Y, Li WB, Yang Z, Hoffman RM, Yu C. PMID: 30952707.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    167. P-Glycoprotein Overexpression Is Associated With Cisplatin Resistance in Human Osteosarcoma. Anticancer Res. 2019 Apr; 39(4):1711-1718. He C, Sun Z, Hoffman RM, Yang Z, Jiang Y, Wang L, Hao Y. PMID: 30952710.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    168. Surgical and histological boundary of the hepatic hilar plate system: basic study relevant to surgery for hilar cholangiocarcinoma regarding the "true" proximal ductal margin. J Hepatobiliary Pancreat Sci. 2019 May; 26(5):159-168. Kikuchi Y, Matuyama R, Hiroshima Y, Murakami T, Bouvet M, Morioka D, Hoffman RM, Endo I. PMID: 30825363.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    169. The combination of olaratumab with gemcitabine and docetaxel arrests a chemotherapy-resistant undifferentiated soft-tissue sarcoma in a patient-derived orthotopic xenograft mouse model. Cancer Chemother Pharmacol. 2019 06; 83(6):1075-1082. Higuchi T, Miyake K, Sugisawa N, Oshiro H, Zhang Z, Razmjooei S, Yamamoto N, Hayashi K, Kimura H, Miwa S, Igarashi K, Bouvet M, Singh SR, Tsuchiya H, Hoffman RM. PMID: 30929053.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    170. Olaratumab combined with doxorubicin and ifosfamide overcomes individual doxorubicin and olaratumab resistance of an undifferentiated soft-tissue sarcoma in a PDOX mouse model. Cancer Lett. 2019 06 01; 451:122-127. Higuchi T, Miyake K, Sugisawa N, Oshiro H, Zhang Z, Razmjooei S, Yamamoto N, Hayashi K, Kimura H, Miwa S, Igarashi K, Bouvet M, Singh SR, Tsuchiya H, Hoffman RM. PMID: 30867142.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    171. β-Catenin Expression Correlates With Prognosis in Hepatocellular Carcinoma Patients Treated With Transcatheter Arterial Chemoembolization. Anticancer Res. 2019 Mar; 39(3):1129-1134. Xu X, Gao D, Yuan X, Liu LI, Zhang X, Liang X, Chen S, Ai M, Chen BO, Shi D, Yang Z, Hoffman RM, Xu J. PMID: 30842141.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    172. A patient-derived orthotopic xenograft (PDOX) nude-mouse model precisely identifies effective and ineffective therapies for recurrent leiomyosarcoma. Pharmacol Res. 2019 04; 142:169-175. Zhang Z, Hu K, Kiyuna T, Miyake K, Kawaguchi K, Igarashi K, Nelson SD, Li Y, Singh SR, Hoffman RM. PMID: 30807865.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimals
    173. Osimertinib Regresses an EGFR-Mutant Cisplatinum- Resistant Lung Adenocarcinoma Growing in the Brain in Nude Mice. Transl Oncol. 2019 Apr; 12(4):640-645. Higuchi T, Oshiro H, Zhang Z, Miyake K, Sugisawa N, Katsuya Y, Yamamoto N, Hayashi K, Kimura H, Miwa S, Igarashi K, Zhao M, Bouvet M, Singh SR, Tsuchiya H, Hoffman RM. PMID: 30807997; PMCID: PMC6393699.
      View in: PubMed   Mentions: 5  
    174. Regorafenib regressed a doxorubicin-resistant Ewing's sarcoma in a patient-derived orthotopic xenograft (PDOX) nude mouse model. Cancer Chemother Pharmacol. 2019 05; 83(5):809-815. Miyake K, Kiyuna T, Kawaguchi K, Higuchi T, Oshiro H, Zhang Z, Wangsiricharoen S, Razmjooei S, Li Y, Nelson SD, Murakami T, Hiroshima Y, Matsuyama R, Bouvet M, Chawla SP, Singh SR, Endo I, Hoffman RM. PMID: 30758647.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    175. Hair-Follicle-Associated Pluripotent (HAP) Stem Cells Encapsulated on Polyvinylidene Fluoride Membranes (PFM) Promote Functional Recovery from Spinal Cord Injury. Stem Cell Rev Rep. 2019 02; 15(1):59-66. Obara K, Tohgi N, Shirai K, Mii S, Hamada Y, Arakawa N, Aki R, Singh SR, Hoffman RM, Amoh Y. PMID: 30341634.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    176. Combining Tumor-Selective Bacterial Therapy with Salmonella typhimurium A1-R and Cancer Metabolism Targeting with Oral Recombinant Methioninase Regressed an Ewing's Sarcoma in a Patient-Derived Orthotopic Xenograft Model. Chemotherapy. 2018; 63(5):278-283. Miyake K, Kiyuna T, Li S, Han Q, Tan Y, Zhao M, Oshiro H, Kawaguchi K, Higuchi T, Zhang Z, Razmjooei S, Barangi M, Wangsiricharoen S, Murakami T, Singh AS, Li Y, Nelson SD, Eilber FC, Bouvet M, Hiroshima Y, Chishima T, Matsuyama R, Singh SR, Endo I, Hoffman RM. PMID: 30673664.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    177. Gemcitabine combined with docetaxel precisely regressed a recurrent leiomyosarcoma peritoneal metastasis in a patient-derived orthotopic xenograft (PDOX) model. Biochem Biophys Res Commun. 2019 02 19; 509(4):1041-1046. Miyake K, Kiyuna T, Miyake M, Kawaguchi K, Zhang Z, Wangsiricharoen S, Razmjooei S, Oshiro H, Higuchi T, Li Y, Nelson SD, Murakami T, Hiroshima Y, Kumamoto T, Matsuyama R, Bouvet M, Singh SR, Chawla SP, Endo I, Hoffman RM. PMID: 30660363.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    178. The combination of gemcitabine and nab-paclitaxel as a novel effective treatment strategy for undifferentiated soft-tissue sarcoma in a patient-derived orthotopic xenograft (PDOX) nude-mouse model. Biomed Pharmacother. 2019 Mar; 111:835-840. Higuchi T, Kawaguchi K, Miyake K, Oshiro H, Zhang Z, Razmjooei S, Wangsiricharoen S, Igarashi K, Yamamoto N, Hayashi K, Kimura H, Miwa S, Nelson SD, Dry SM, Li Y, Chawla SP, Eilber FC, Singh SR, Tsuchiya H, Hoffman RM. PMID: 30616082.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    179. Role of the tumor microenvironment in pancreatic cancer. Ann Gastroenterol Surg. 2019 Mar; 3(2):130-137. Murakami T, Hiroshima Y, Matsuyama R, Homma Y, Hoffman RM, Endo I. PMID: 30923782; PMCID: PMC6422798.
      View in: PubMed   Mentions: 24  
    180. Altered Methionine Metabolism in Cancer Cells. Methods Mol Biol. 2019; 1866:13-26. Hoffman RM, Stern PH, Coalson DW, Douglas Wallace C, Erbe RW. PMID: 30725404.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    181. Linkage of Methionine Dependence and Other Features of Malignancy. Methods Mol Biol. 2019; 1866:27-36. Hoffman RM, Erbe RW. PMID: 30725405.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    182. Tumor-Specific S/G2-Phase Cell Cycle Arrest of Cancer Cells by Methionine Restriction. Methods Mol Biol. 2019; 1866:49-60. Hoffman RM, Yano S. PMID: 30725407.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    183. Efficacy of Methionine-Restricted Diets on Cancers In Vivo. Methods Mol Biol. 2019; 1866:75-81. Hoffman RM, Hoshiya Y, Guo W. PMID: 30725409.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    184. Dietary Methionine Restriction-Based Cancer Chemotherapy in Rodents. Methods Mol Biol. 2019; 1866:83-94. Hoffman RM, Stern PH. PMID: 30725410.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    185. Clinical Studies of Methionine-Restricted Diets for Cancer Patients. Methods Mol Biol. 2019; 1866:95-105. Hoffman RM. PMID: 30725411.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    186. Development of Recombinant Methioninase for Cancer Treatment. Methods Mol Biol. 2019; 1866:107-131. Hoffman RM, Tan Y, Li S, Han Q, Yagi S, Takakura T, Takimoto A, Inagaki K, Kudou D. PMID: 30725412.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    187. Methioninase Cell-Cycle Trap Cancer Chemotherapy. Methods Mol Biol. 2019; 1866:133-148. Hoffman RM, Yano S, Igarashi K. PMID: 30725413.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    188. High Efficacy of Recombinant Methioninase on Patient-Derived Orthotopic Xenograft (PDOX) Mouse Models of Cancer. Methods Mol Biol. 2019; 1866:149-161. Hoffman RM, Murakami T, Kawaguchi K, Igarashi K, Tan Y, Li S, Han Q. PMID: 30725414.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    189. Total Methionine Restriction Treatment of Cancer. Methods Mol Biol. 2019; 1866:163-171. Hoffman RM, Kokkinakis DM, Frenkel EP. PMID: 30725415.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    190. Methioninase Gene Therapy. Methods Mol Biol. 2019; 1866:173-197. Hoffman RM, Miki K, Al-Refaie W, Xu M, Tan Y. PMID: 30725416.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    191. Safety and Toxicity of Recombinant Methioninase and Polyethylene Glycol (PEG) Recombinant Methioninase in Primates. Methods Mol Biol. 2019; 1866:211-229. Hoffman RM, Yang Z, Tan Y, Han Q, Li S, Yagi S. PMID: 30725418.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    192. Pilot Phase I Clinical Trial of Methioninase on High-Stage Cancer Patients: Rapid Depletion of Circulating Methionine. Methods Mol Biol. 2019; 1866:231-242. Hoffman RM, Tan Y, Li S, Han Q, Zavala J, Zavala J. PMID: 30725419.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCellsCTClinical Trials
    193. Methionine Restriction and Life-Span Extension. Methods Mol Biol. 2019; 1866:263-266. Hoffman RM. PMID: 30725421.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    194. L-[Methyl-11C] Methionine-Positron-Emission Tomography (MET-PET). Methods Mol Biol. 2019; 1866:267-271. Hoffman RM. PMID: 30725422.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    195. Is the Hoffman Effect for Methionine Overuse Analogous to the Warburg Effect for Glucose Overuse in Cancer? Methods Mol Biol. 2019; 1866:273-278. Hoffman RM. PMID: 30725423.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    196. Recombinant Methioninase as a DNA Demethylation Agent. Methods Mol Biol. 2019; 1866:279-284. Hoffman RM, Machover D. PMID: 30725424.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    197. Afterword: Oral Methioninase-Answer to Cancer and Fountain of Youth? Methods Mol Biol. 2019; 1866:311-322. Hoffman RM, Han Q, Kawaguchi K, Li S, Tan Y. PMID: 30725426.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    198. Detection of Metastasis in a Patient-derived Orthotopic Xenograft (PDOX) Model of Undifferentiated Pleomorphic Sarcoma with Red Fluorescent Protein. Anticancer Res. 2019 Jan; 39(1):81-85. Oshiro H, Kiyuna T, Tome Y, Miyake K, Kawaguchi K, Higuchi T, Miyake M, Zhang Z, Razmjooei S, Barangi M, Wangsiricharoen S, Nelson SD, Li Y, Bouvet M, Singh SR, Kanaya F, Hoffman RM. PMID: 30591443.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    199. Human Hair Follicle Associated-Pluripotent (hHAP) Stem Cells Differentiate to Cardiac Muscle Cells. Methods Mol Biol. 2019; 1879:385-392. Hoffman RM. PMID: 29992514.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    200. Fluorescent humanized anti-CEA antibody specifically labels metastatic pancreatic cancer in a patient-derived orthotopic xenograft (PDOX) mouse model. Oncotarget. 2018 Dec 18; 9(99):37333-37342. Lwin TM, Miyake K, Murakami T, DeLong JC, Amirfakhri S, Filemoni F, Yoon SN, Yazaki PJ, Shivley JE, Datnow B, Clary BM, Hoffman RM, Bouvet M. PMID: 30647873; PMCID: PMC6324662.
      View in: PubMed   Mentions: 7     Fields:    
    201. Fluorescent Proteins as Sensors for Cellular Behavior in Mice. Prog Mol Biol Transl Sci. 2018; 160:29-45. Hoffman RM. PMID: 30470291.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    202. Metabolic targeting with recombinant methioninase combined with palbociclib regresses a doxorubicin-resistant dedifferentiated liposarcoma. Biochem Biophys Res Commun. 2018 12 02; 506(4):912-917. Igarashi K, Kawaguchi K, Kiyuna T, Miyake K, Miyaki M, Yamamoto N, Hayashi K, Kimura H, Miwa S, Higuchi T, Singh AS, Chmielowski B, Nelson SD, Russell TA, Eckardt MA, Dry SM, Li Y, Singh SR, Chawla SP, Eilber FC, Tsuchiya H, Hoffman RM. PMID: 30392912.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimals
    203. Hair Follicle-Associated Pluripotent(HAP) Stem Cells. Prog Mol Biol Transl Sci. 2018; 160:23-28. Hoffman RM, Amoh Y. PMID: 30470290.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    204. Real-Time Determination of the Cell-Cycle Position of Individual Cells within Live Tumors Using FUCCI Cell-Cycle Imaging. Cells. 2018 Oct 14; 7(10). Yano S, Hoffman RM. PMID: 30322204; PMCID: PMC6210921.
      View in: PubMed   Mentions: 8     Fields:    
    205. A combination of irinotecan/cisplatinum and irinotecan/temozolomide or tumor-targeting Salmonella typhimurium A1-R arrest doxorubicin- and temozolomide-resistant myxofibrosarcoma in a PDOX mouse model. Biochem Biophys Res Commun. 2018 11 02; 505(3):733-739. Kiyuna T, Tome Y, Murakami T, Miyake K, Igarashi K, Kawaguchi K, Oshiro H, Higuchi T, Miyake M, Sugisawa N, Zhang Z, Razmjooei S, Wangsiricharoen S, Chmielowski B, Nelson SD, Russell TA, Dry SM, Li Y, Eckardt MA, Singh AS, Chawla S, Kanaya F, Eilber FC, Singh SR, Zhao M, Hoffman RM. PMID: 30292411.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    206. Color-coded Imaging of the Circulating Tumor Cell Microenvironment. Anticancer Res. 2018 Oct; 38(10):5635-5638. Satake T, Suetsugu A, Nakamura M, Kunisada T, Shimizu M, Saji S, Moriwaki H, Hoffman RM. PMID: 30275181.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    207. Oral Recombinant Methioninase Combined with Caffeine and Doxorubicin Induced Regression of a Doxorubicin-resistant Synovial Sarcoma in a PDOX Mouse Model. Anticancer Res. 2018 Oct; 38(10):5639-5644. Higuchi T, Kawaguchi K, Miyake K, Han Q, Tan Y, Oshiro H, Sugisawa N, Zhang Z, Razmjooei S, Yamamoto N, Hayashi K, Kimura H, Miwa S, Igarashi K, Chawla SP, Singh AS, Eilber FC, Singh SR, Tsuchiya H, Hoffman RM. PMID: 30275182.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    208. Tumor targeting Salmonella typhimurium A1-R in combination with gemcitabine (GEM) regresses partially GEM-resistant pancreatic cancer patient-derived orthotopic xenograft (PDOX) nude mouse models. Cell Cycle. 2018; 17(16):2019-2026. Kawaguchi K, Miyake K, Zhao M, Kiyuna T, Igarashi K, Miyake M, Higuchi T, Oshiro H, Bouvet M, Unno M, Hoffman RM. PMID: 29963961; PMCID: PMC6224272.
      View in: PubMed   Mentions: 4  Translation:HumansAnimalsCells
    209. Tumor-targeting Salmonella typhimurium A1-R overcomes partial carboplatinum-resistance of a cancer of unknown primary (CUP). Tissue Cell. 2018 Oct; 54:144-149. Miyake K, Kiyuna T, Miyake M, Zhao M, Wangsiricharoen S, Kawaguchi K, Zhang Z, Higuchi T, Razmjooei S, Li Y, Nelson SD, Russell T, Singh A, Murakami T, Hiroshima Y, Momiyama M, Matsuyama R, Chishima T, Singh SR, Chawla SP, Eilber FC, Endo I, Hoffman RM. PMID: 30309504.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    210. Ultrasound Microbubble Delivery Targeting Intraplaque Neovascularization Inhibits Atherosclerotic Plaque in an APOE-deficient Mouse Model. In Vivo. 2018 Sep-Oct; 32(5):1025-1032. Yuan H, Hu H, Sun J, Shi M, Yu H, Li C, Sun YU, Yang Z, Hoffman RM. PMID: 30150423; PMCID: PMC6199608.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    211. Combination therapy of tumor-targeting Salmonella typhimurium A1-R and oral recombinant methioninase regresses a BRAF-V600E-negative melanoma. Biochem Biophys Res Commun. 2018 09 18; 503(4):3086-3092. Kawaguchi K, Higuchi T, Li S, Han Q, Tan Y, Igarashi K, Zhao M, Miyake K, Kiyuna T, Miyake M, Ohshiro H, Sugisawa N, Zhang Z, Razmjooei S, Wangsiricharoen S, Chmielowski B, Nelson SD, Russell TA, Dry SM, Li Y, Eckardt MA, Singh AS, Singh SR, Eilber FC, Unno M, Hoffman RM. PMID: 30166061.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    212. Imaging the interaction of αv integrin-GFP in osteosarcoma cells with RFP-expressing host stromal cells and tumor-scaffold collagen in the primary and metastatic tumor microenvironment. J Cell Biochem. 2019 01; 120(1):283-289. Tome Y, Kiyuna T, Uehara F, Bouvet M, Tsuchiya H, Kanaya F, Hoffman RM. PMID: 30145815.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    213. Patterns of sensitivity to a panel of drugs are highly individualised for undifferentiated/unclassified soft tissue sarcoma (USTS) in patient-derived orthotopic xenograft (PDOX) nude-mouse models. J Drug Target. 2019 02; 27(2):211-216. Kawaguchi K, Igarashi K, Miyake K, Kiyuna T, Miyake M, Singh AS, Chmielowski B, Nelson SD, Russell TA, Dry SM, Li Y, Unno M, Singh SR, Eilber FC, Hoffman RM. PMID: 30024282.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    214. Trabectedin arrests a doxorubicin-resistant PDGFRA-activated liposarcoma patient-derived orthotopic xenograft (PDOX) nude mouse model. BMC Cancer. 2018 Aug 20; 18(1):840. Kiyuna T, Tome Y, Murakami T, Kawaguchi K, Igarashi K, Miyake K, Miyake M, Li Y, Nelson SD, Dry SM, Singh AS, Russell TA, Elliott I, Singh SR, Kanaya F, Eilber FC, Hoffman RM. PMID: 30126369; PMCID: PMC6102848.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    215. Advantages of patient-derived orthotopic mouse models and genetic reporters for developing fluorescence-guided surgery. J Surg Oncol. 2018 Aug; 118(2):253-264. Lwin TM, Hoffman RM, Bouvet M. PMID: 30080930; PMCID: PMC6146062.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    216. White paper on microbial anti-cancer therapy and prevention. J Immunother Cancer. 2018 08 06; 6(1):78. Forbes NS, Coffin RS, Deng L, Evgin L, Fiering S, Giacalone M, Gravekamp C, Gulley JL, Gunn H, Hoffman RM, Kaur B, Liu K, Lyerly HK, Marciscano AE, Moradian E, Ruppel S, Saltzman DA, Tattersall PJ, Thorne S, Vile RG, Zhang HH, Zhou S, McFadden G. PMID: 30081947; PMCID: PMC6091193.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    217. Intravital microscopy of osteolytic progression and therapy response of cancer lesions in the bone. Sci Transl Med. 2018 08 01; 10(452). Dondossola E, Alexander S, Holzapfel BM, Filippini S, Starbuck MW, Hoffman RM, Navone N, De-Juan-Pardo EM, Logothetis CJ, Hutmacher DW, Friedl P. PMID: 30068572; PMCID: PMC6326183.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    218. Color-coded Imaging Distinguishes Cancer Cells, Stromal Cells, and Recombinant Cancer-stromal Cells in the Tumor Microenvironment During Metastasis. Anticancer Res. 2018 Aug; 38(8):4417-4423. Nakamura M, Suetsugu A, Hasegawa K, Satake T, Kunisada T, Shimizu M, Saji S, Moriwaki H, Hoffman RM. PMID: 30061205.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    219. Analysis of Anticancer Activity and Chemical Sensitization Effects of Dendropanax morbifera and Commersonia bartramia Extracts. Anticancer Res. 2018 Jul; 38(7):3853-3861. Kim S, Park SG, Song YJ, Park JK, Choi CH, Lee S, Hoffman RM. PMID: 29970505.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    220. Tumor-targeting Salmonella typhimurium A1-R arrests a doxorubicin-resistant PDGFRA-amplified patient-derived orthotopic xenograft mouse model of pleomorphic liposarcoma. J Cell Biochem. 2018 09; 119(9):7827-7833. Kiyuna T, Tome Y, Murakami T, Zhao M, Miyake K, Igarashi K, Kawaguchi K, Miyake M, Oshiro H, Higuchi T, Li Y, Dry SM, Nelson SD, Russell TA, Eckardt MA, Singh AS, Kanaya F, Eilber FC, Hoffman RM. PMID: 29932244; PMCID: PMC6150816.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    221. Oral recombinant methioninase (o-rMETase) is superior to injectable rMETase and overcomes acquired gemcitabine resistance in pancreatic cancer. Cancer Lett. 2018 09 28; 432:251-259. Kawaguchi K, Miyake K, Han Q, Li S, Tan Y, Igarashi K, Kiyuna T, Miyake M, Higuchi T, Oshiro H, Zhang Z, Razmjooei S, Wangsiricharoen S, Bouvet M, Singh SR, Unno M, Hoffman RM. PMID: 29928962.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    222. In silico-designed mutations increase variable new-antigen receptor single-domain antibodies for VEGF165 neutralization. Oncotarget. 2018 Jun 15; 9(46):28016-28029. Millán-Gómez D, Dueñas S, Muñoz PLA, Camacho-Villegas T, Elosua C, Cabanillas-Bernal O, Escalante T, Perona A, Abia D, Drescher F, Fournier PGJ, Ramos MA, Mares RE, Paniagua-Solis J, Mata-Gonzalez T, Gonzalez-Canudas J, Hoffman RM, Licea-Navarro A, Sánchez-Campos N. PMID: 29963259; PMCID: PMC6021326.
      View in: PubMed   Mentions:    Fields:    
    223. Erratum: Publisher Correction: Is DNA methylation the new guardian of the genome? Mol Cytogenet. 2018; 11:38. Hoffman RM. PMID: 29946362; PMCID: PMC6001167.
      View in: PubMed   Mentions:
    224. Tumor-targeting Salmonella typhimurium A1-R suppressed an imatinib-resistant gastrointestinal stromal tumor with c-kit exon 11 and 17 mutations. Heliyon. 2018 Jun; 4(6):e00643. Miyake K, Kawaguchi K, Miyake M, Zhao M, Kiyuna T, Igarashi K, Zhang Z, Murakami T, Li Y, Nelson SD, Bouvet M, Elliott I, Russell TA, Singh AS, Hiroshima Y, Momiyama M, Matsuyama R, Chishima T, Singh SR, Endo I, Eilber FC, Hoffman RM. PMID: 30003151; PMCID: PMC6040627.
      View in: PubMed   Mentions: 2  
    225. Moesin Up-regulation Is Associated with Enhanced Tumor Progression Imaged Non-invasively in an Orthotopic Mouse Model of Human Glioblastoma. Anticancer Res. 2018 Jun; 38(6):3267-3272. Wang Q, Lu X, Wang J, Yang Z, Hoffman RM, Wu X. PMID: 29848673.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    226. The development of fluorescence guided surgery for pancreatic cancer: from bench to clinic. Expert Rev Anticancer Ther. 2018 07; 18(7):651-662. Lwin TM, Hoffman RM, Bouvet M. PMID: 29768067; PMCID: PMC6298876.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimals
    227. Doxorubicin-resistant pleomorphic liposarcoma with PDGFRA gene amplification is targeted and regressed by pazopanib in a patient-derived orthotopic xenograft mouse model. Tissue Cell. 2018 Aug; 53:30-36. Kiyuna T, Murakami T, Tome Y, Igarashi K, Kawaguchi K, Miyake K, Miyake M, Li Y, Nelson SD, Dry SM, Singh AS, Russell TA, Singh SR, Kanaya F, Eilber FC, Hoffman RM. PMID: 30060824.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimals
    228. Targeting altered cancer methionine metabolism with recombinant methioninase (rMETase) overcomes partial gemcitabine-resistance and regresses a patient-derived orthotopic xenograft (PDOX) nude mouse model of pancreatic cancer. Cell Cycle. 2018; 17(7):868-873. Kawaguchi K, Miyake K, Han Q, Li S, Tan Y, Igarashi K, Lwin TM, Higuchi T, Kiyuna T, Miyake M, Oshiro H, Bouvet M, Unno M, Hoffman RM. PMID: 29623758; PMCID: PMC6056209.
      View in: PubMed   Mentions: 2  Translation:HumansAnimals
    229. Temozolomide regresses a doxorubicin-resistant undifferentiated spindle-cell sarcoma patient-derived orthotopic xenograft (PDOX): precision-oncology nude-mouse model matching the patient with effective therapy. J Cell Biochem. 2018 08; 119(8):6598-6603. Igarashi K, Kawaguchi K, Kiyuna T, Miyake K, Miyake M, Li Y, Nelson SD, Dry SM, Singh AS, Elliott IA, Russell TA, Eckardt MA, Yamamoto N, Hayashi K, Kimura H, Miwa S, Tsuchiya H, Eilber FC, Hoffman RM. PMID: 29737543.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCTClinical Trials
    230. MEK inhibitor trametinib in combination with gemcitabine regresses a patient-derived orthotopic xenograft (PDOX) pancreatic cancer nude mouse model. Tissue Cell. 2018 Jun; 52:124-128. Kawaguchi K, Igarashi K, Miyake K, Lwin TM, Miyake M, Kiyuna T, Hwang HK, Murakami T, Delong JC, Singh SR, Clary B, Bouvet M, Unno M, Hoffman RM. PMID: 29857821.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    231. Exploiting methionine restriction for cancer treatment. Biochem Pharmacol. 2018 08; 154:170-173. Chaturvedi S, Hoffman RM, Bertino JR. PMID: 29733806.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    232. Patient-derived orthotopic xenograft models for cancer of unknown primary precisely distinguish chemotherapy, and tumor-targeting S. typhimurium A1-R is superior to first-line chemotherapy. Signal Transduct Target Ther. 2018; 3:12. Miyake K, Kiyuna T, Miyake M, Kawaguchi K, Yoon SN, Zhang Z, Igarashi K, Razmjooei S, Wangsiricharoen S, Murakami T, Li Y, Nelson SD, Russell TA, Singh AS, Hiroshima Y, Momiyama M, Matsuyama R, Chishima T, Singh SR, Endo I, Eilber FC, Hoffman RM. PMID: 29713497; PMCID: PMC5923205.
      View in: PubMed   Mentions:
    233. Recombinant methioninase combined with doxorubicin (DOX) regresses a DOX-resistant synovial sarcoma in a patient-derived orthotopic xenograft (PDOX) mouse model. Oncotarget. 2018 Apr 10; 9(27):19263-19272. Igarashi K, Kawaguchi K, Li S, Han Q, Tan Y, Gainor E, Kiyuna T, Miyake K, Miyake M, Higuchi T, Oshiro H, Singh AS, Eckardt MA, Nelson SD, Russell TA, Dry SM, Li Y, Yamamoto N, Hayashi K, Kimura H, Miwa S, Tsuchiya H, Eilber FC, Hoffman RM. PMID: 29721200; PMCID: PMC5922394.
      View in: PubMed   Mentions: 3     Fields:    
    234. Tumor-targeting Salmonella typhimurium A1-R combined with recombinant methioninase and cisplatinum eradicates an osteosarcoma cisplatinum-resistant lung metastasis in a patient-derived orthotopic xenograft (PDOX) mouse model: decoy, trap and kill chemotherapy moves toward the clinic. Cell Cycle. 2018; 17(6):801-809. Igarashi K, Kawaguchi K, Kiyuna T, Miyake K, Miyake M, Li S, Han Q, Tan Y, Zhao M, Li Y, Nelson SD, Dry SM, Singh AS, Elliott IA, Russell TA, Eckardt MA, Yamamoto N, Hayashi K, Kimura H, Miwa S, Tsuchiya H, Eilber FC, Hoffman RM. PMID: 29374999; PMCID: PMC5969544.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    235. Visualizing the Tumor Microenvironment by Color-coded Imaging in Orthotopic Mouse Models of Cancer. Anticancer Res. 2018 04; 38(4):1847-1857. Suetsugu A, Shimizu M, Saji S, Moriwaki H, Hoffman RM. PMID: 29599301.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    236. Ethanolic Extract of Traditional Chinese Medicine (TCM) Gamboge Inhibits Colon Cancer via the Wnt/Beta-Catenin Signaling Pathway in an Orthotopic Mouse Model. Anticancer Res. 2018 04; 38(4):1917-1925. Wang W, Li Y, Chen Y, Chen H, Zhu P, Xu M, Wang H, Wu M, Yang Z, Hoffman RM, Gu Y. PMID: 29599307.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    237. Differential Organ-targeting and Cellular Characteristics of Metastatic Human Pancreatic Cancer Cell Lines in Mouse Models. Anticancer Res. 2018 04; 38(4):1927-1935. Satake T, Suetsugu A, Nakamura M, Hasegawa K, Kunisada T, Shimizu M, Saji S, Moriwaki H, Hoffman RM. PMID: 29599308.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    238. Individualized doxorubicin sensitivity testing of undifferentiated soft tissue sarcoma (USTS) in a patient-derived orthotopic xenograft (PDOX) model demonstrates large differences between patients. Cell Cycle. 2018; 17(5):627-633. Kawaguchi K, Igarashi K, Kiyuna T, Miyake K, Miyake M, Murakami T, Chmielowski B, Nelson SD, Russell TA, Dry SM, Li Y, Singh AS, Unno M, Eilber FC, Hoffman RM. PMID: 29384032; PMCID: PMC5969558.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    239. Targeting methionine with oral recombinant methioninase (o-rMETase) arrests a patient-derived orthotopic xenograft (PDOX) model of BRAF-V600E mutant melanoma: implications for chronic clinical cancer therapy and prevention. Cell Cycle. 2018; 17(3):356-361. Kawaguchi K, Han Q, Li S, Tan Y, Igarashi K, Kiyuna T, Miyake K, Miyake M, Chmielowski B, Nelson SD, Russell TA, Dry SM, Li Y, Singh AS, Eckardt MA, Unno M, Eilber FC, Hoffman RM. PMID: 29187018; PMCID: PMC5914727.
      View in: PubMed   Mentions: 9  Translation:HumansAnimals
    240. Tumor-targeting Salmonella typhimurium A1-R is a highly effective general therapeutic for undifferentiated soft tissue sarcoma patient-derived orthotopic xenograft nude-mouse models. Biochem Biophys Res Commun. 2018 03 18; 497(4):1055-1061. Igarashi K, Kawaguchi K, Kiyuna T, Miyake K, Miyake M, Singh AS, Eckardt MA, Nelson SD, Russell TA, Dry SM, Li Y, Yamamoto N, Hayashi K, Kimura H, Miwa S, Tsuchiya H, Singh SR, Eilber FC, Hoffman RM. PMID: 29481803.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    241. RT-PCR of peritoneal washings predicts peritoneal pancreatic cancer recurrence. J Surg Res. 2018 06; 226:122-130. Sato K, Mori R, Hiroshima Y, Oba MS, Matsuyama R, Bouvet M, Hoffman RM, Endo I. PMID: 29661277.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    242. Fluorescence-guided Surgery with Splenic Preservation Prevents Tumor Recurrence in an Orthotopic Nude-mouse Model of Human Pancreatic Cancer. Anticancer Res. 2018 02; 38(2):665-670. Hwang HK, Kang CM, Lee SH, Murakami T, Kiyuna T, Kim SH, Hoffman RM, Bouvet M. PMID: 29374688.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    243. Inhibition of growth and metastasis of triple-negative breast cancer targeted by Traditional Chinese Medicine Tubeimu in orthotopic mice models. Chin J Cancer Res. 2018 Feb; 30(1):112-121. Wang J, Yang X, Han H, Wang L, Bao W, Wang S, Hoffman RM, Yang M, Qi H, An C, Hu K. PMID: 29545725; PMCID: PMC5842225.
      View in: PubMed   Mentions: 4  
    244. Tumor-Specific Labeling of Pancreatic Cancer Using a Humanized Anti-CEA Antibody Conjugated to a Near-Infrared Fluorophore. Ann Surg Oncol. 2018 Apr; 25(4):1079-1085. Lwin TM, Murakami T, Miyake K, Yazaki PJ, Shivley JE, Hoffman RM, Bouvet M. PMID: 29372363; PMCID: PMC5842124.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    245. Bacterial Therapy of Cancer: Promises, Limitations, and Insights for Future Directions. Front Microbiol. 2018; 9:16. Kramer MG, Masner M, Ferreira FA, Hoffman RM. PMID: 29472896; PMCID: PMC5810261.
      View in: PubMed   Mentions: 21  
    246. Intra-tumor L-methionine level highly correlates with tumor size in both pancreatic cancer and melanoma patient-derived orthotopic xenograft (PDOX) nude-mouse models. Oncotarget. 2018 Feb 16; 9(13):11119-11125. Kawaguchi K, Han Q, Li S, Tan Y, Igarashi K, Miyake K, Kiyuna T, Miyake M, Chemielwski B, Nelson SD, Russell TA, Dry SM, Li Y, Singh AS, Eckardt MA, Unno M, Eilber FC, Hoffman RM. PMID: 29541401; PMCID: PMC5834286.
      View in: PubMed   Mentions: 9     Fields:    
    247. Engineered mesenchymal stem-cell-sheets patches prevents postoperative pancreatic leakage in a rat model. Sci Rep. 2018 01 10; 8(1):360. Kim SR, Yi HJ, Lee YN, Park JY, Hoffman RM, Okano T, Shim IK, Kim SC. PMID: 29321630; PMCID: PMC5762914.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    248. Recombinant methioninase in combination with doxorubicin (DOX) overcomes first-line DOX resistance in a patient-derived orthotopic xenograft nude-mouse model of undifferentiated spindle-cell sarcoma. Cancer Lett. 2018 03 28; 417:168-173. Igarashi K, Kawaguchi K, Li S, Han Q, Tan Y, Murakami T, Kiyuna T, Miyake K, Miyake M, Singh AS, Eckardt MA, Nelson SD, Russell TA, Dry SM, Li Y, Yamamoto N, Hayashi K, Kimura H, Miwa S, Tsuchiya H, Singh SR, Eilber FC, Hoffman RM. PMID: 29306021.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimals
    249. Growth of doxorubicin-resistant undifferentiated spindle-cell sarcoma PDOX is arrested by metabolic targeting with recombinant methioninase. J Cell Biochem. 2018 04; 119(4):3537-3544. Igarashi K, Li S, Han Q, Tan Y, Kawaguchi K, Murakami T, Kiyuna T, Miyake K, Li Y, Nelson SD, Dry SM, Singh AS, Elliott IA, Russell TA, Eckardt MA, Yamamoto N, Hayashi K, Kimura H, Miwa S, Tsuchiya H, Eilber FC, Hoffman RM. PMID: 29143983.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    250. Regorafenib regresses an imatinib-resistant recurrent gastrointestinal stromal tumor (GIST) with a mutation in exons 11 and 17 of c-kit in a patient-derived orthotopic xenograft (PDOX) nude mouse model. Cell Cycle. 2018; 17(6):722-727. Miyake K, Kawaguchi K, Kiyuna T, Miyake M, Igarashi K, Zhang Z, Murakami T, Li Y, Nelson SD, Elliott I, Russell T, Singh A, Hiroshima Y, Momiyama M, Matsuyama R, Chishima T, Endo I, Eilber FC, Hoffman RM. PMID: 29334307; PMCID: PMC5969563.
      View in: PubMed   Mentions: 3  Translation:HumansAnimalsCells
    251. Traditional Chinese Medicine Curcumin Sensitizes Human Colon Cancer to Radiation by Altering the Expression of DNA Repair-related Genes. Anticancer Res. 2018 01; 38(1):131-136. Yang G, Qiu J, Wang D, Tao Y, Song Y, Wang H, Tang J, Wang X, Sun YU, Yang Z, Hoffman RM. PMID: 29277765.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    252. Tumor-targeting Salmonella typhimurium A1-R Inhibits Osteosarcoma Angiogenesis in the In Vivo Gelfoam® Assay Visualized by Color-coded Imaging. Anticancer Res. 2018 01; 38(1):159-164. Kiyuna T, Tome Y, Uehara F, Murakami T, Zhang Y, Zhao M, Kanaya F, Hoffman RM. PMID: 29277768.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    253. Effects of siRNA Silencing of TUG1 and LCAL6 Long Non-coding RNAs on Patient-derived Xenograft of Non-small Cell Lung Cancer. Anticancer Res. 2018 01; 38(1):179-186. Fang T, Huang H, Li X, Liao J, Yang Z, Hoffman RM, Cheng XI, Liang L, Hu W, Yun S. PMID: 29277771.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    254. 3D Sponge-Matrix Histoculture: An Overview. Methods Mol Biol. 2018; 1760:11-17. Hoffman RM. PMID: 29572789.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    255. In Vivo-Like Growth Patterns of Multiple Types of Tumors in Gelfoam® Histoculture. Methods Mol Biol. 2018; 1760:19-28. Hoffman RM, Freeman AE. PMID: 29572790.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    256. Expression and Targeting of Tumor Markers in Gelfoam® Histoculture: Potential Individualized Assays for Immuno-Oncology. Methods Mol Biol. 2018; 1760:29-37. Hoffman RM, Guadagni F. PMID: 29572791.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    257. Development of the Histoculture Drug Response Assay (HDRA). Methods Mol Biol. 2018; 1760:39-48. Hoffman RM, Vescio RA. PMID: 29572792.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    258. Diagnosis and Pathological Analysis of Patient Cancers by Detection of Proliferating Cells in Gelfoam® Histoculture. Methods Mol Biol. 2018; 1760:49-60. Hoffman RM. PMID: 29572793.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    259. Clinical Correlation of the Histoculture Drug Response Assay in Gastrointestinal Cancer. Methods Mol Biol. 2018; 1760:61-72. Hoffman RM. PMID: 29572794.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    260. Clinical Correlation of the Histoculture Drug Response Assay for Head and Neck Cancer. Methods Mol Biol. 2018; 1760:83-92. Hoffman RM. PMID: 29572796.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    261. Clinical Usefulness of the Histoculture Drug Response Assay for Prostate Cancer and Benign Prostate Hypertrophy (BPH). Methods Mol Biol. 2018; 1760:101-107. Hoffman RM. PMID: 29572798.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    262. In Vivo-Like Cell-Cycle Phase Distribution of Cancer Cells in Gelfoam® Histoculture Observed in Real Time by FUCCI Imaging. Methods Mol Biol. 2018; 1760:109-123. Hoffman RM, Yano S. PMID: 29572799.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    263. Methionine Dependency Determination of Human Patient Tumors in Gelfoam® Histoculture. Methods Mol Biol. 2018; 1760:125-131. Hoffman RM. PMID: 29572800.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    264. Hair-Shaft Growth in Gelfoam® Histoculture of Skin and Isolated Hair Follicles. Methods Mol Biol. 2018; 1760:133-144. Hoffman RM, Li L, Cao W. PMID: 29572801.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    265. Hair Follicle-Associated Pluripotent (HAP) Stem Cells in Gelfoam® Histoculture for Use in Spinal Cord Repair. Methods Mol Biol. 2018; 1760:145-162. Liu F, Hoffman RM. PMID: 29572802.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    266. Nerve Growth and Interaction in Gelfoam® Histoculture: A Nervous System Organoid. Methods Mol Biol. 2018; 1760:163-186. Hoffman RM, Mii S, Duong J, Amoh Y. PMID: 29572803.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    267. Imaging DNA Repair After UV Irradiation Damage of Cancer Cells in Gelfoam® Histoculture. Methods Mol Biol. 2018; 1760:199-203. Miwa S, Hoffman RM. PMID: 29572805.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCellsPHPublic Health
    268. Imaging the Governing Step of Metastasis in Gelfoam® Histoculture. Methods Mol Biol. 2018; 1760:215-220. Hoffman RM, Chishima T. PMID: 29572807.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    269. Prospective Clinical Correlation of the Histoculture Drug Response Assay for Ovarian Cancer. Methods Mol Biol. 2018; 1760:73-81. Hoffman RM, Jung PS, Kim MB, Nam JH. PMID: 29572795.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    270. Clinical Usefulness of the Histoculture Drug Response Assay for Breast Cancer. Methods Mol Biol. 2018; 1760:93-100. Hoffman RM, Tanino H. PMID: 29572797.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    271. Comparison of "Dimensionality" of Cancer Cell Culture in Gelfoam® Histoculture and Matrigel. Methods Mol Biol. 2018; 1760:205-214. Tome Y, Uehara F, Kanaya F, Hoffman RM. PMID: 29572806.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    272. Beating Heart Cells from Hair-Follicle-Associated Pluripotent (HAP) Stem Cells. Methods Mol Biol. 2018; 1842:241-254. Hoffman RM, Amoh Y. PMID: 30196415.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    273. Genetic and metabolic comparison of orthotopic and heterotopic patient-derived pancreatic-cancer xenografts to the original patient tumors. Oncotarget. 2018 Jan 30; 9(8):7867-7881. Jun E, Hong SM, Yoo HJ, Kim MB, Won JS, An S, Shim IK, Chang S, Hoffman RM, Kim SC. PMID: 29487698; PMCID: PMC5814265.
      View in: PubMed   Mentions: 3     Fields:    
    274. Recombinant methioninase (rMETase) is an effective therapeutic for BRAF-V600E-negative as well as -positive melanoma in patient-derived orthotopic xenograft (PDOX) mouse models. Oncotarget. 2018 Jan 02; 9(1):915-923. Kawaguchi K, Igarashi K, Li S, Han Q, Tan Y, Miyake K, Kiyuna T, Miyake M, Murakami T, Chmielowski B, Nelson SD, Russell TA, Dry SM, Li Y, Unno M, Eilber FC, Hoffman RM. PMID: 29416666; PMCID: PMC5787523.
      View in: PubMed   Mentions: 13     Fields:    
    275. Temozolomide combined with irinotecan regresses a cisplatinum-resistant relapsed osteosarcoma in a patient-derived orthotopic xenograft (PDOX) precision-oncology mouse model. Oncotarget. 2018 Jan 30; 9(8):7774-7781. Igarashi K, Kawaguchi K, Kiyuna T, Miyake K, Miyake M, Li Y, Nelson SD, Dry SM, Singh AS, Elliott IA, Russell TA, Eckardt MA, Yamamoto N, Hayashi K, Kimura H, Miwa S, Tsuchiya H, Eilber FC, Hoffman RM. PMID: 29487690; PMCID: PMC5814257.
      View in: PubMed   Mentions: 6     Fields:    
    276. Near-infrared-conjugated humanized anti-carcinoembryonic antigen antibody targets colon cancer in an orthotopic nude-mouse model. J Surg Res. 2017 10; 218:139-143. DeLong JC, Murakami T, Yazaki PJ, Hoffman RM, Bouvet M. PMID: 28985840; PMCID: PMC5650098.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    277. Splenectomy is associated with an aggressive tumor growth pattern and altered host immunity in an orthotopic syngeneic murine pancreatic cancer model. Oncotarget. 2017 Oct 24; 8(51):88827-88834. Hwang HK, Murakami T, Kiyuna T, Kim SH, Lee SH, Kang CM, Hoffman RM, Bouvet M. PMID: 29179479; PMCID: PMC5687649.
      View in: PubMed   Mentions: 1     Fields:    
    278. Regarding the applications of fusion-fluorescence imaging using indocyanine green in laparoscopic hepatectomy. Transl Gastroenterol Hepatol. 2017; 2:70. Lwin TM, Hoffman RM, Bouvet M. PMID: 29034343; PMCID: PMC5638993.
      View in: PubMed   Mentions: 1  
    279. Eribulin regresses a doxorubicin-resistant Ewing's sarcoma with a FUS-ERG fusion and CDKN2A-deletion in a patient-derived orthotopic xenograft (PDOX) nude mouse model. J Cell Biochem. 2018 01; 119(1):967-972. Miyake K, Murakami T, Kiyuna T, Igarashi K, Kawaguchi K, Li Y, Singh AS, Dry SM, Eckardt MA, Hiroshima Y, Momiyama M, Matsuyama R, Chishima T, Endo I, Eilber FC, Hoffman RM. PMID: 28681998.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    280. Implanted hair-follicle-associated pluripotent (HAP) stem cells encapsulated in polyvinylidene fluoride membrane cylinders promote effective recovery of peripheral nerve injury. Cell Cycle. 2017 Oct 18; 16(20):1927-1932. Yamazaki A, Obara K, Tohgi N, Shirai K, Mii S, Hamada Y, Arakawa N, Aki R, Hoffman RM, Amoh Y. PMID: 28886268; PMCID: PMC5638363.
      View in: PubMed   Mentions: 5  Translation:AnimalsCells
    281. The combination of temozolomide-irinotecan regresses a doxorubicin-resistant patient-derived orthotopic xenograft (PDOX) nude-mouse model of recurrent Ewing's sarcoma with a FUS-ERG fusion and CDKN2A deletion: Direction for third-line patient therapy. Oncotarget. 2017 Nov 28; 8(61):103129-103136. Miyake K, Murakami T, Kiyuna T, Igarashi K, Kawaguchi K, Miyake M, Li Y, Nelson SD, Dry SM, Bouvet M, Elliott IA, Russell TA, Singh AS, Eckardt MA, Hiroshima Y, Momiyama M, Matsuyama R, Chishima T, Endo I, Eilber FC, Hoffman RM. PMID: 29262551; PMCID: PMC5732717.
      View in: PubMed   Mentions: 16     Fields:    
    282. Hair follicle-associated-pluripotent (HAP) stem cells. Cell Cycle. 2017; 16(22):2169-2175. Amoh Y, Hoffman RM. PMID: 28749199; PMCID: PMC5736337.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    283. Effective Metabolic Targeting of Human Osteosarcoma Cells In Vitro and in Orthotopic Nude-mouse Models with Recombinant Methioninase. Anticancer Res. 2017 09; 37(9):4807-4812. Igarashi K, Kawaguchi K, Kiyuna T, Miyake K, Murakami T, Yamamoto N, Hayashi K, Kimura H, Miwa S, Tsuchiya H, Hoffman RM. PMID: 28870899.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    284. Patient-Derived Orthotopic Xenograft (PDOX) Models of Melanoma. Int J Mol Sci. 2017 Aug 31; 18(9). Hoffman RM. PMID: 28858204; PMCID: PMC5618524.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimals
    285. Combination treatment with recombinant methioninase enables temozolomide to arrest a BRAF V600E melanoma in a patient-derived orthotopic xenograft (PDOX) mouse model. Oncotarget. 2017 Oct 17; 8(49):85516-85525. Kawaguchi K, Igarashi K, Li S, Han Q, Tan Y, Kiyuna T, Miyake K, Murakami T, Chmielowski B, Nelson SD, Russell TA, Dry SM, Li Y, Unno M, Eilber FC, Hoffman RM. PMID: 29156737; PMCID: PMC5689627.
      View in: PubMed   Mentions: 20     Fields:    
    286. Tumor-Targeting Salmonella typhimurium A1-R Promotes Tumoricidal CD8+ T Cell Tumor Infiltration and Arrests Growth and Metastasis in a Syngeneic Pancreatic-Cancer Orthotopic Mouse Model. J Cell Biochem. 2018 01; 119(1):634-639. Murakami T, Hiroshima Y, Zhang Y, Zhao M, Kiyuna T, Hwang HK, Miyake K, Homma Y, Mori R, Matsuyama R, Chishima T, Ichikawa Y, Tanaka K, Bouvet M, Endo I, Hoffman RM. PMID: 28628234.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    287. Clinical Factors That Affect the Establishment of Soft Tissue Sarcoma Patient-Derived Orthotopic Xenografts: A University of California, Los Angeles, Sarcoma Program Prospective Clinical Trial. JCO Precis Oncol. 2017; 2017. Russell TA, Eckardt MA, Murakami T, Elliott IA, Kawaguchi K, Kiyuna T, Igarashi K, Li Y, Crompton JG, Graham DS, Dry SM, Bernthal N, Yanagawa J, Kalbasi A, Federman N, Chmielowski B, Singh AS, Hoffman RM, Eilber FC. PMID: 30613825; PMCID: PMC6319895.
      View in: PubMed   Mentions: 1  
    288. Chemoprevention by Quercetin of Oral Squamous Cell Carcinoma by Suppression of the NF-κB Signaling Pathway in DMBA-treated Hamsters. Anticancer Res. 2017 08; 37(8):4041-4049. Zhang W, Yin G, Dai J, Sun YU, Hoffman RM, Yang Z, Fan Y. PMID: 28739686.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    289. Efficacy In Vitro of Caffeine and Valproic Acid on Patient-Derived Undifferentiated Pleomorphic Sarcoma and Rhabdomyosarcoma Cell Lines. Anticancer Res. 2017 08; 37(8):4081-4084. Igarashi K, Kawaguchi K, Kiyuna T, Murakami T, Miwa S, Nelson SD, Dry SM, Li Y, Singh AS, Kimura H, Hayashi K, Yamamoto N, Tsuchiya H, Eilber FC, Hoffman RM. PMID: 28739691.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    290. Therapeutic Cell-Cycle-Decoy Efficacy of a Telomerase-Dependent Adenovirus in an Orthotopic Model of Chemotherapy-Resistant Human Stomach Carcinomatosis Peritonitis Visualized With FUCCI Imaging. J Cell Biochem. 2017 11; 118(11):3635-3642. Yano S, Takehara K, Tazawa H, Kishimoto H, Urata Y, Kagawa S, Fujiwara T, Hoffman RM. PMID: 27171483.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    291. MEK inhibitors cobimetinib and trametinib, regressed a gemcitabine-resistant pancreatic-cancer patient-derived orthotopic xenograft (PDOX). Oncotarget. 2017 Jul 18; 8(29):47490-47496. Kawaguchi K, Igarashi K, Murakami T, Kiyuna T, Lwin TM, Hwang HK, Delong JC, Clary BM, Bouvet M, Unno M, Hoffman RM. PMID: 28537897; PMCID: PMC5564580.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    292. A patient-derived orthotopic xenograft (PDOX) mouse model of a cisplatinum-resistant osteosarcoma lung metastasis that was sensitive to temozolomide and trabectedin: implications for precision oncology. Oncotarget. 2017 Sep 22; 8(37):62111-62119. Igarashi K, Murakami T, Kawaguchi K, Kiyuna T, Miyake K, Zhang Y, Nelson SD, Dry SM, Li Y, Yanagawa J, Russell TA, Singh AS, Tsuchiya H, Elliott I, Eilber FC, Hoffman RM. PMID: 28977930; PMCID: PMC5617490.
      View in: PubMed   Mentions: 21     Fields:    
    293. Enhancement of Wound Healing by the Traditional Chinese Medicine Herbal Mixture Sophora flavescens in a Rat Model of Perianal Ulceration. In Vivo. 2017 Jul-Aug; 31(4):543-549. Xu X, Li X, Zhang L, Liu Z, Pan Y, Chen D, Bin D, Deng Q, Sun YU, Hoffman RM, Yang Z, Yuan H. PMID: 28652418; PMCID: PMC5566901.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    294. Choline-Deficient-Diet-Induced Fatty Liver Is a Metastasis-Resistant Microenvironment. Anticancer Res. 2017 07; 37(7):3429-3434. Nakamura M, Suetsugu A, Hasegawa K, Matsumoto T, Aoki H, Kunisada T, Shimizu M, Saji S, Moriwaki H, Hoffman RM. PMID: 28668831.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    295. Imaging the Role of Multinucleate Pancreatic Cancer Cells and Cancer-Associated Fibroblasts in Peritoneal Metastasis in Mouse Models. Anticancer Res. 2017 07; 37(7):3435-3440. Hasegawa K, Suetsugu A, Nakamura M, Matsumoto T, Aoki H, Kunisada T, Shimizu M, Saji S, Moriwaki H, Hoffman RM. PMID: 28668832.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    296. On the role of classical and novel forms of vitamin D in melanoma progression and management. J Steroid Biochem Mol Biol. 2018 03; 177:159-170. Slominski AT, Brozyna AA, Skobowiat C, Zmijewski MA, Kim TK, Janjetovic Z, Oak AS, Jozwicki W, Jetten AM, Mason RS, Elmets C, Li W, Hoffman RM, Tuckey RC. PMID: 28676457; PMCID: PMC5748362.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimals
    297. A novel anionic-phosphate-platinum complex effectively targets an undifferentiated pleomorphic sarcoma better than cisplatinum and doxorubicin in a patient-derived orthotopic xenograft (PDOX). Oncotarget. 2017 Sep 08; 8(38):63353-63359. Igarashi K, Kawaguchi K, Murakami T, Kiyuna T, Miyake K, Yamamoto N, Hayashi K, Kimura H, Nelson SD, Dry SM, Li Y, Singh AS, Miwa S, Odani A, Eilber FC, Tsuchiya H, Hoffman RM. PMID: 28968995; PMCID: PMC5609927.
      View in: PubMed   Mentions: 11     Fields:    
    298. Pancreatic cancer-derived exosomes promote tumor metastasis and liver pre-metastatic niche formation. Oncotarget. 2017 Sep 08; 8(38):63461-63483. Yu Z, Zhao S, Ren L, Wang L, Chen Z, Hoffman RM, Zhou J. PMID: 28969005; PMCID: PMC5609937.
      View in: PubMed   Mentions: 34     Fields:    
    299. Locally-applied 5-fluorouracil-loaded slow-release patch prevents pancreatic cancer growth in an orthotopic mouse model. Oncotarget. 2017 Jun 20; 8(25):40140-40151. Shim IK, Yi HJ, Yi HG, Lee CM, Lee YN, Choi YJ, Jeong SY, Jun E, Hoffman RM, Cho DW, Kim SC. PMID: 28498800; PMCID: PMC5522260.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    300. Salmonella typhimurium A1-R targeting of a chemotherapy-resistant BRAF-V600E melanoma in a patient-derived orthotopic xenograft (PDOX) model is enhanced in combination with either vemurafenib or temozolomide. Cell Cycle. 2017 Jul 03; 16(13):1288-1294. Kawaguchi K, Igarashi K, Murakami T, Kiyuna T, Zhao M, Zhang Y, Nelson SD, Russell TA, Dry SM, Singh AS, Chmielowski B, Li Y, Unno M, Eilber FC, Hoffman RM. PMID: 28622068; PMCID: PMC5531627.
      View in: PubMed   Mentions: 18  Translation:HumansAnimalsCells
    301. Neoadjuvant chemoradiotherapy of pancreatic cancer induces a favorable immunogenic tumor microenvironment associated with increased major histocompatibility complex class I-related chain A/B expression. J Surg Oncol. 2017 Sep; 116(3):416-426. Murakami T, Homma Y, Matsuyama R, Mori R, Miyake K, Tanaka Y, Den K, Nagashima Y, Nakazawa M, Hiroshima Y, Ueda M, Tanaka K, Hoffman RM, Bouvet M, Endo I. PMID: 28608409.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    302. Genetic Recombination Between Stromal and Cancer Cells Results in Highly Malignant Cells Identified by Color-Coded Imaging in a Mouse Lymphoma Model. J Cell Biochem. 2017 12; 118(12):4216-4221. Nakamura M, Suetsugu A, Hasegawa K, Matsumoto T, Aoki H, Kunisada T, Shimizu M, Saji S, Moriwaki H, Hoffman RM. PMID: 28419513.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    303. Recombinant methioninase effectively targets a Ewing's sarcoma in a patient-derived orthotopic xenograft (PDOX) nude-mouse model. Oncotarget. 2017 May 30; 8(22):35630-35638. Murakami T, Li S, Han Q, Tan Y, Kiyuna T, Igarashi K, Kawaguchi K, Hwang HK, Miyake K, Singh AS, Nelson SD, Dry SM, Li Y, Hiroshima Y, Lwin TM, DeLong JC, Chishima T, Tanaka K, Bouvet M, Endo I, Eilber FC, Hoffman RM. PMID: 28404944; PMCID: PMC5482604.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimals
    304. Strategies for In Vivo Imaging Using Fluorescent Proteins. J Cell Biochem. 2017 09; 118(9):2571-2580. Hoffman RM. PMID: 27564860.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    305. Analysis of Stroma Labeling During Multiple Passage of a Sarcoma Imageable Patient-Derived Orthotopic Xenograft (iPDOX) in Red Fluorescent Protein Transgenic Nude Mice. J Cell Biochem. 2017 10; 118(10):3367-3371. Kiyuna T, Murakami T, Tome Y, Kawaguchi K, Igarashi K, Miyake K, Kanaya F, Singh A, Eilber FC, Hoffman RM. PMID: 28300287; PMCID: PMC5550328.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    306. Intra-arterial administration of tumor-targeting Salmonella typhimurium A1-R regresses a cisplatin-resistant relapsed osteosarcoma in a patient-derived orthotopic xenograft (PDOX) mouse model. Cell Cycle. 2017 Jun 18; 16(12):1164-1170. Igarashi K, Kawaguchi K, Murakami T, Kiyuna T, Miyake K, Nelson SD, Dry SM, Li Y, Yanagawa J, Russell TA, Singh AS, Yamamoto N, Hayashi K, Kimura H, Miwa S, Tsuchiya H, Eilber FC, Hoffman RM. PMID: 28494180; PMCID: PMC5499917.
      View in: PubMed   Mentions: 21  Translation:HumansAnimalsCells
    307. Toxicology and efficacy of tumor-targeting Salmonella typhimurium A1-R compared to VNP 20009 in a syngeneic mouse tumor model in immunocompetent mice. Oncotarget. 2017 Aug 15; 8(33):54616-54628. Zhang Y, Cao W, Toneri M, Zhang N, Kiyuna T, Murakami T, Nelson SD, Dry SM, Li Y, Li S, Wang X, Ma H, Singh AS, Eilber FC, Hoffman RM, Zhao M. PMID: 28903369; PMCID: PMC5589608.
      View in: PubMed   Mentions: 6     Fields:    
    308. Moesin Expression Is Associated with Glioblastoma Cell Proliferation and Invasion. Anticancer Res. 2017 05; 37(5):2211-2218. Wang Q, Lu X, Zhao S, Pang M, Wu X, Wu H, Hoffman RM, Yang Z, Zhang Y. PMID: 28476784.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    309. High Efficacy of Pazopanib on an Undifferentiated Spindle-Cell Sarcoma Resistant to First-Line Therapy Is Identified With a Patient-Derived Orthotopic Xenograft (PDOX) Nude Mouse Model. J Cell Biochem. 2017 09; 118(9):2739-2743. Igarashi K, Kawaguchi K, Murakami T, Kiyuna T, Miyake K, Singh AS, Nelson SD, Dry SM, Li Y, Yamamoto N, Hayashi K, Kimura H, Miwa S, Tsuchiya H, Eilber FC, Hoffman RM. PMID: 28176365.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimals
    310. Tumor-Targeting Salmonella typhimurium A1-R Sensitizes Melanoma With a BRAF-V600E Mutation to Vemurafenib in a Patient-Derived Orthotopic Xenograft (PDOX) Nude Mouse Model. J Cell Biochem. 2017 08; 118(8):2314-2319. Kawaguchi K, Igarashi K, Murakami T, Zhao M, Zhang Y, Chmielowski B, Kiyuna T, Nelson SD, Russell TA, Dry SM, Li Y, Unno M, Eilber FC, Hoffman RM. PMID: 28106277.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    311. Color-coded intravital imaging demonstrates a transforming growth factor-β (TGF-β) antagonist selectively targets stromal cells in a human pancreatic-cancer orthotopic mouse model. Cell Cycle. 2017 May 19; 16(10):1008-1014. Murakami T, Hiroshima Y, Miyake K, Hwang HK, Kiyuna T, DeLong JC, Lwin TM, Matsuyama R, Mori R, Kumamoto T, Chishima T, Tanaka K, Ichikawa Y, Bouvet M, Endo I, Hoffman RM. PMID: 28441080; PMCID: PMC5462077.
      View in: PubMed   Mentions: 4  Translation:HumansAnimalsCells
    312. Combination of gemcitabine and docetaxel regresses both gastric leiomyosarcoma proliferation and invasion in an imageable patient-derived orthotopic xenograft (iPDOX) model. Cell Cycle. 2017 Jun 03; 16(11):1063-1069. Kawaguchi K, Igarashi K, Murakami T, Kiyuna T, Nelson SD, Dry SM, Li Y, Russell TA, Singh AS, Chmielowski B, Unno M, Eilber FC, Hoffman RM. PMID: 28426279; PMCID: PMC5499841.
      View in: PubMed   Mentions: 12  Translation:HumansAnimals
    313. Is DNA methylation the new guardian of the genome? Mol Cytogenet. 2017; 10:11. Hoffman RM. PMID: 28396696; PMCID: PMC5381125.
      View in: PubMed   Mentions: 8  
    314. Temozolomide combined with irinotecan caused regression in an adult pleomorphic rhabdomyosarcoma patient-derived orthotopic xenograft (PDOX) nude-mouse model. Oncotarget. 2017 Sep 29; 8(44):75874-75880. Igarashi K, Kawaguchi K, Kiyuna T, Murakami T, Miwa S, Nelson SD, Dry SM, Li Y, Singh AS, Kimura H, Hayashi K, Yamamoto N, Tsuchiya H, Eilber FC, Hoffman RM. PMID: 29100276; PMCID: PMC5652670.
      View in: PubMed   Mentions: 17     Fields:    
    315. High-efficacy targeting of colon-cancer liver metastasis with Salmonella typhimurium A1-R via intra-portal-vein injection in orthotopic nude-mouse models. Oncotarget. 2017 Mar 21; 8(12):19065-19073. Kawaguchi K, Murakami T, Suetsugu A, Kiyuna T, Igarashi K, Hiroshima Y, Zhao M, Zhang Y, Bouvet M, Clary BM, Unno M, Hoffman RM. PMID: 27683127; PMCID: PMC5386670.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    316. The wayward methyl group and the cascade to cancer. Cell Cycle. 2017 May 03; 16(9):825-829. Hoffman RM. PMID: 28318368; PMCID: PMC5444351.
      View in: PubMed   Mentions: 5  Translation:HumansAnimalsCells
    317. The irony of highly-effective bacterial therapy of a patient-derived orthotopic xenograft (PDOX) model of Ewing's sarcoma, which was blocked by Ewing himself 80 years ago. Cell Cycle. 2017 Jun 03; 16(11):1046-1052. Murakami T, Kiyuna T, Kawaguchi K, Igarashi K, Singh AS, Hiroshima Y, Zhang Y, Zhao M, Miyake K, Nelson SD, Dry SM, Li Y, DeLong JC, Lwin TM, Chishima T, Tanaka K, Bouvet M, Endo I, Eilber FC, Hoffman RM. PMID: 28296559; PMCID: PMC5499836.
      View in: PubMed   Mentions: 13  Translation:HumansAnimalsCells
    318. Anti-metastatic Efficacy of Traditional Chinese Medicine (TCM) Ginsenoside Conjugated to a VEFGR-3 Antibody on Human Gastric Cancer in an Orthotopic Mouse Model. Anticancer Res. 2017 03; 37(3):979-986. Dai X, Liu D, Liu M, Zhang X, Wang W, Jin F, Qian Y, Wang X, Zhao J, Wu Y, Xiong F, Chang NA, Sun YU, Yang Z, Hoffman RM, Liu Y. PMID: 28314255.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    319. Antimetastatic Efficacy of the Combination of Caffeine and Valproic Acid on an Orthotopic Human Osteosarcoma Cell Line Model in Nude Mice. Anticancer Res. 2017 03; 37(3):1005-1011. Igarashi K, Kawaguchi K, Kiyuna T, Murakami T, Yamamoto N, Hayashi K, Kimura H, Miwa S, Tsuchiya H, Hoffman RM. PMID: 28314258.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    320. Potential of immunotherapy for sarcoma. Cancer. 2017 05 01; 123(9):1488-1489. Hoffman RM, Singh AS, Eilber FC. PMID: 28241102.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    321. GFP labeling kinetics of triple-negative human breast cancer by a killer-reporter adenovirus in 3D Gelfoam® histoculture. In Vitro Cell Dev Biol Anim. 2017 Jun; 53(6):479-482. Yano S, Takehara K, Miwa S, Kishimoto H, Tazawa H, Urata Y, Kagawa S, Bouvet M, Fujiwara T, Hoffman RM. PMID: 28233141.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    322. Synergistic Inhibitory Effect of Traditional Chinese Medicine Astragaloside IV and Curcumin on Tumor Growth and Angiogenesis in an Orthotopic Nude-Mouse Model of Human Hepatocellular Carcinoma. Anticancer Res. 2017 02; 37(2):465-473. Zhang S, Tang D, Zang W, Yin G, Dai J, Sun YU, Yang Z, Hoffman RM, Guo X. PMID: 28179291.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    323. Tumor-targeting Salmonella typhimurium A1-R regresses an osteosarcoma in a patient-derived xenograft model resistant to a molecular-targeting drug. Oncotarget. 2017 Jan 31; 8(5):8035-8042. Murakami T, Igarashi K, Kawaguchi K, Kiyuna T, Zhang Y, Zhao M, Hiroshima Y, Nelson SD, Dry SM, Li Y, Yanagawa J, Russell T, Federman N, Singh A, Elliott I, Matsuyama R, Chishima T, Tanaka K, Endo I, Eilber FC, Hoffman RM. PMID: 28030831; PMCID: PMC5352380.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    324. High-metastatic triple-negative breast-cancer variants selected in vivo become chemoresistant in vitro. In Vitro Cell Dev Biol Anim. 2017 Apr; 53(4):285-287. Yano S, Takehara K, Kishimoto H, Tazawa H, Urata Y, Kagawa S, Bouvet M, Fujiwara T, Hoffman RM. PMID: 28127701.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    325. A novel method for RNA extraction from FFPE samples reveals significant differences in biomarker expression between orthotopic and subcutaneous pancreatic cancer patient-derived xenografts. Oncotarget. 2017 Jan 24; 8(4):5885-5894. Hoover M, Adamian Y, Brown M, Maawy A, Chang A, Lee J, Gharibi A, Katz MH, Fleming J, Hoffman RM, Bouvet M, Doebler R, Kelber JA. PMID: 27602776; PMCID: PMC5351598.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimals
    326. Reconstitution of a metastatic-resistant tumor microenvironment with cancer-associated fibroblasts enables metastasis. Cell Cycle. 2017 Mar 19; 16(6):533-535. Murata T, Mekada E, Hoffman RM. PMID: 28103135; PMCID: PMC5384587.
      View in: PubMed   Mentions: 6  Translation:HumansAnimalsCells
    327. Eradication of melanoma in vitro and in vivo via targeting with a Killer-Red-containing telomerase-dependent adenovirus. Cell Cycle. 2017 Aug 18; 16(16):1502-1508. Takehara K, Yano S, Tazawa H, Kishimoto H, Narii N, Mizuguchi H, Urata Y, Kagawa S, Fujiwara T, Hoffman RM. PMID: 28055296; PMCID: PMC5584861.
      View in: PubMed   Mentions: 3  Translation:HumansAnimalsCells
    328. Comparison of Tumor Recurrence After Resection of Highly- and Poorly-Metastatic Triple-negative Breast Cancer in Orthotopic Nude-Mouse Models. Anticancer Res. 2017 01; 37(1):57-60. Yano S, Takehara K, Kishimoto H, Tazawa H, Urata Y, Kagawa S, Fujiwara T, Bouvet M, Hoffman RM. PMID: 28011473.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    329. Cervical Cancer Patient-Derived Orthotopic Xenograft (PDOX) Is Sensitive to Cisplatinum and Resistant to Nab-paclitaxel. Anticancer Res. 2017 01; 37(1):61-65. Murakami T, Murata T, Kawaguchi K, Kiyuna T, Igarashi K, Hwang HK, Hiroshima Y, Hozumi C, Komatsu S, Kikuchi T, Lwin TM, Delong JC, Miyake K, Zhang Y, Tanaka K, Bouvet M, Endo I, Hoffman RM. PMID: 28011474; PMCID: PMC5831332.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    330. The disintegrin echistatin in combination with doxorubicin targets high-metastatic human osteosarcoma overexpressing ανβ3 integrin in chick embryo and nude mouse models. Oncotarget. 2016 Dec 27; 7(52):87031-87036. Tome Y, Kimura H, Sugimoto N, Tsuchiya H, Kanaya F, Bouvet M, Hoffman RM. PMID: 27894082; PMCID: PMC5349968.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    331. Tumor-targeting Salmonella typhimurium A1-R combined with temozolomide regresses malignant melanoma with a BRAF-V600E mutation in a patient-derived orthotopic xenograft (PDOX) model. Oncotarget. 2016 Dec 27; 7(52):85929-85936. Kawaguchi K, Igarashi K, Murakami T, Chmielowski B, Kiyuna T, Zhao M, Zhang Y, Singh A, Unno M, Nelson SD, Russell TA, Dry SM, Li Y, Eilber FC, Hoffman RM. PMID: 27835903; PMCID: PMC5349886.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansAnimalsCells
    332. Tumor-targeting adenovirus OBP-401 inhibits primary and metastatic tumor growth of triple-negative breast cancer in orthotopic nude-mouse models. Oncotarget. 2016 Dec 20; 7(51):85273-85282. Yano S, Takehara K, Kishimoto H, Tazawa H, Urata Y, Kagawa S, Bouvet M, Fujiwara T, Hoffman RM. PMID: 27863373; PMCID: PMC5356735.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    333. BRCAness and Prognosis in Triple-Negative Breast Cancer Patients Treated with Neoadjuvant Chemotherapy. PLoS One. 2016; 11(12):e0165721. Tanino H, Kosaka Y, Nishimiya H, Tanaka Y, Minatani N, Kikuchi M, Shida A, Waraya M, Katoh H, Enomoto T, Sengoku N, Kajita S, Hoffman RM, Watanabe M. PMID: 27935989; PMCID: PMC5147808.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    334. In Vivo Selection of Intermediately- and Highly-Malignant Variants of Triple-negative Breast Cancer in Orthotopic Nude Mouse Models. Anticancer Res. 2016 12; 36(12):6273-6277. Yano S, Takehara K, Kishimoto H, Tazawa H, Urata Y, Kagawa S, Bouvet M, Fujiwara T, Hoffman RM. PMID: 27919946.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    335. Human hair-follicle associated pluripotent (hHAP) stem cells differentiate to cardiac-muscle cells. Cell Cycle. 2017 Jan 02; 16(1):95-99. Tohgi N, Obara K, Yashiro M, Hamada Y, Arakawa N, Mii S, Aki R, Hoffman RM, Amoh Y. PMID: 27880068; PMCID: PMC5270544.
      View in: PubMed   Mentions: 6  Translation:HumansCells
    336. Efficacy of glycogen synthase kinase-3β targeting against osteosarcoma via activation of β-catenin. Oncotarget. 2016 Nov 22; 7(47):77038-77051. Shimozaki S, Yamamoto N, Domoto T, Nishida H, Hayashi K, Kimura H, Takeuchi A, Miwa S, Igarashi K, Kato T, Aoki Y, Higuchi T, Hirose M, Hoffman RM, Minamoto T, Tsuchiya H. PMID: 27780915; PMCID: PMC5363568.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    337. Fluorescence-guided surgery of a highly-metastatic variant of human triple-negative breast cancer targeted with a cancer-specific GFP adenovirus prevents recurrence. Oncotarget. 2016 11 15; 7(46):75635-75647. Yano S, Takehara K, Miwa S, Kishimoto H, Tazawa H, Urata Y, Kagawa S, Bouvet M, Fujiwara T, Hoffman RM. PMID: 27689331; PMCID: PMC5342766.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    338. Patient-derived orthotopic xenograft (PDOX) mouse model of adult rhabdomyosarcoma invades and recurs after resection in contrast to the subcutaneous ectopic model. Cell Cycle. 2017 Jan 02; 16(1):91-94. Igarashi K, Kawaguchi K, Kiyuna T, Murakami T, Miwa S, Nelson SD, Dry SM, Li Y, Singh A, Kimura H, Hayashi K, Yamamoto N, Tsuchiya H, Eilber FC, Hoffman RM. PMID: 27830986; PMCID: PMC5270546.
      View in: PubMed   Mentions: 20  Translation:HumansAnimals
    339. Vemurafenib-resistant BRAF-V600E-mutated melanoma is regressed by MEK-targeting drug trametinib, but not cobimetinib in a patient-derived orthotopic xenograft (PDOX) mouse model. Oncotarget. 2016 Nov 01; 7(44):71737-71743. Kawaguchi K, Murakami T, Chmielowski B, Igarashi K, Kiyuna T, Unno M, Nelson SD, Russell TA, Dry SM, Li Y, Eilber FC, Hoffman RM. PMID: 27690220; PMCID: PMC5342117.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansAnimals
    340. Patient-derived mouse models of cancer need to be orthotopic in order to evaluate targeted anti-metastatic therapy. Oncotarget. 2016 11 01; 7(44):71696-71702. Hiroshima Y, Maawy A, Zhang Y, Zhang N, Murakami T, Chishima T, Tanaka K, Ichikawa Y, Bouvet M, Endo I, Hoffman RM. PMID: 27765934; PMCID: PMC5342112.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimals
    341. Comparison of in vitro invasiveness of high- and low-metastatic triple-negative human breast cancer visualized by color-coded imaging. In Vitro Cell Dev Biol Anim. 2017 Feb; 53(2):96-98. Yano S, Takehara K, Tazawa H, Kishimoto H, Kagawa S, Fujiwara T, Hoffman RM. PMID: 27778228.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    342. Enhanced Metastatic Recurrence Via Lymphatic Trafficking of a High-Metastatic Variant of Human Triple-Negative Breast Cancer After Surgical Resection in Orthotopic Nude Mouse Models. J Cell Biochem. 2017 03; 118(3):559-569. Yano S, Takehara K, Tazawa H, Kishimoto H, Kagawa S, Bouvet M, Fujiwara T, Hoffman RM. PMID: 27626220.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    343. Effective fluorescence-guided surgery of liver metastasis using a fluorescent anti-CEA antibody. J Surg Oncol. 2016 Dec; 114(8):951-958. Hiroshima Y, Lwin TM, Murakami T, Mawy AA, Kuniya T, Chishima T, Endo I, Clary BM, Hoffman RM, Bouvet M. PMID: 27696448; PMCID: PMC5565879.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    344. Hypoxia Enhances Differentiation of Hair Follicle-Associated-Pluripotent (HAP) Stem Cells to Cardiac-Muscle Cells. J Cell Biochem. 2017 03; 118(3):554-558. Shirai K, Hamada Y, Arakawa N, Yamazaki A, Tohgi N, Aki R, Mii S, Hoffman RM, Amoh Y. PMID: 27627796.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    345. Efficacy of a Cell-Cycle Decoying Killer Adenovirus on 3-D Gelfoam®-Histoculture and Tumor-Sphere Models of Chemo-Resistant Stomach Carcinomatosis Visualized by FUCCI Imaging. PLoS One. 2016; 11(9):e0162991. Yano S, Takehara K, Tazawa H, Kishimoto H, Urata Y, Kagawa S, Fujiwara T, Hoffman RM. PMID: 27673332; PMCID: PMC5038935.
      View in: PubMed   Mentions:    Fields:    
    346. Fluorescent Orthotopic Mouse Model of Pancreatic Cancer. J Vis Exp. 2016 09 20; (115). Moreno JA, Sanchez A, Hoffman RM, Nur S, Lambros MP. PMID: 27685334; PMCID: PMC5092057.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    347. Real-Time GFP Intravital Imaging of the Differences in Cellular and Angiogenic Behavior of Subcutaneous and Orthotopic Nude-Mouse Models of Human PC-3 Prostate Cancer. J Cell Biochem. 2016 11; 117(11):2546-51. Zhang Y, Toneri M, Ma H, Yang Z, Bouvet M, Goto Y, Seki N, Hoffman RM. PMID: 27012365.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    348. A Mouse Model of Fluorescent Protein-expressing Disseminated Peritoneal Lymphoma for Fluorescence-guided Surgery. Anticancer Res. 2016 09; 36(9):4483-7. Matsumoto T, Suetsugu A, Hasegawa K, Nakamura M, Shibata Y, Aoki H, Kunisada T, Tsurumi H, Shimizu M, Bouvet M, Hoffman RM. PMID: 27630285.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    349. Non-toxic Efficacy of the Combination of Caffeine and Valproic Acid on Human Osteosarcoma Cells In Vitro and in Orthotopic Nude-mouse Models. Anticancer Res. 2016 09; 36(9):4477-82. Igarashi K, Yamamoto N, Hayashi K, Takeuchi A, Kimura H, Miwa S, Hoffman RM, Tsuchiya H. PMID: 27630284.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    350. Color-coded Imaging Enables Fluorescence-guided Surgery to Resect the Tumor Along with the Tumor Microenvironment in a Syngeneic Mouse Model of EL-4 Lymphoma. Anticancer Res. 2016 09; 36(9):4443-8. Hasegawa K, Suetsugu A, Nakamura M, Matsumoto T, Kunisada T, Shimizu M, Saji S, Moriwaki H, Bouvet M, Hoffman RM. PMID: 27630280.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    351. Cell-cycle-dependent drug-resistant quiescent cancer cells induce tumor angiogenesis after chemotherapy as visualized by real-time FUCCI imaging. Cell Cycle. 2017 Mar 04; 16(5):406-414. Yano S, Takehara K, Tazawa H, Kishimoto H, Urata Y, Kagawa S, Fujiwara T, Hoffman RM. PMID: 27715464; PMCID: PMC5351920.
      View in: PubMed   Mentions: 10  Translation:HumansAnimalsCells
    352. Efficacy of Tumor-Targeting Salmonella A1-R on a Melanoma Patient-Derived Orthotopic Xenograft (PDOX) Nude-Mouse Model. PLoS One. 2016; 11(8):e0160882. Yamamoto M, Zhao M, Hiroshima Y, Zhang Y, Shurell E, Eilber FC, Bouvet M, Noda M, Hoffman RM. PMID: 27500926; PMCID: PMC4976963.
      View in: PubMed   Mentions: 51     Fields:    Translation:HumansAnimalsCells
    353. Color-coded Live Imaging of Heterokaryon Formation and Nuclear Fusion of Hybridizing Cancer Cells. Anticancer Res. 2016 Aug; 36(8):3827-31. Suetsugu A, Matsumoto T, Hasegawa K, Nakamura M, Kunisada T, Shimizu M, Saji S, Moriwaki H, Bouvet M, Hoffman RM. PMID: 27466484.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    354. Use of αv Integrin Linked to Green Fluorescent Protein in Osteosarcoma Cells and Confocal Microscopy to Image Molecular Dynamics During Lung Metastasis in Nude Mice. Anticancer Res. 2016 Aug; 36(8):3811-6. Tome Y, Yano S, Sugimoto N, Mii S, Uehara F, Miwa S, Bouvet M, Tsuchiya H, Kanaya F, Hoffman RM. PMID: 27466481.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    355. In Vivo Isolation of a Highly-aggressive Variant of Triple-negative Human Breast Cancer MDA-MB-231 Using Serial Orthotopic Transplantation. Anticancer Res. 2016 Aug; 36(8):3817-20. Yano S, Takehara K, Miwa S, Kishimoto H, Tazawa H, Urata Y, Kagawa S, Bouvet M, Fujiwara T, Hoffman RM. PMID: 27466482.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    356. Efficacy of the Combination of a PARP Inhibitor and UVC on Cancer Cells as Imaged by Focus Formation by the DNA Repair-related Protein 53BP1 Linked to Green Fluorescent Protein. Anticancer Res. 2016 Aug; 36(8):3821-6. Tome Y, Uehara F, Miwa S, Yano S, Mii S, Efimova EV, Bouvet M, Kimura H, Tsuchiya H, Kanaya F, Hoffman RM. PMID: 27466483.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    357. Effective molecular targeting of CDK4/6 and IGF-1R in a rare FUS-ERG fusion CDKN2A-deletion doxorubicin-resistant Ewing's sarcoma patient-derived orthotopic xenograft (PDOX) nude-mouse model. Oncotarget. 2016 Jul 26; 7(30):47556-47564. Murakami T, Singh AS, Kiyuna T, Dry SM, Li Y, James AW, Igarashi K, Kawaguchi K, DeLong JC, Zhang Y, Hiroshima Y, Russell T, Eckardt MA, Yanagawa J, Federman N, Matsuyama R, Chishima T, Tanaka K, Bouvet M, Endo I, Eilber FC, Hoffman RM. PMID: 27286459; PMCID: PMC5216960.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansAnimals
    358. Disintegrin targeting of an αvβ3 integrin-over-expressing high-metastatic human osteosarcoma with echistatin inhibits cell proliferation, migration, invasion and adhesion in vitro. Oncotarget. 2016 07 19; 7(29):46315-46320. Tome Y, Kimura H, Kiyuna T, Sugimoto N, Tsuchiya H, Kanaya F, Bouvet M, Hoffman RM. PMID: 27331872; PMCID: PMC5216800.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    359. Early-age-dependent selective decrease of differentiation potential of hair-follicle-associated pluripotent (HAP) stem cells to beating cardiac-muscle cells. Cell Cycle. 2016 Oct; 15(19):2619-2625. Yamazaki A, Hamada Y, Arakawa N, Yashiro M, Mii S, Aki R, Kawahara K, Hoffman RM, Amoh Y. PMID: 27428074; PMCID: PMC5053548.
      View in: PubMed   Mentions: 3  Translation:AnimalsCells
    360. Labeling the Stroma of a Patient-Derived Orthotopic Xenograft (PDOX) Mouse Model of Undifferentiated Pleomorphic Soft-Tissue Sarcoma With Red Fluorescent Protein for Rapid Non-Invasive Imaging for Drug Screening. J Cell Biochem. 2017 02; 118(2):361-365. Kiyuna T, Murakami T, Tome Y, Igarashi K, Kawaguchi K, Russell T, Eckardt MA, Crompton J, Singh A, Bernthal N, Bukata S, Federman N, Kanaya F, Eilber FC, Hoffman RM. PMID: 27357060.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimals
    361. Use of αv Integrin Linked to GFP to Image Molecular Dynamics in Trafficking Cancer-Cell Emboli. J Cell Biochem. 2017 01; 118(1):26-30. Tome Y, Yano S, Sugimoto N, Mii S, Bouvet M, Tsuchiya H, Kanaya F, Hoffman RM. PMID: 27191371.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    362. Solid tumors provide niche-specific conditions that lead to preferential growth of Salmonella. Oncotarget. 2016 Jun 07; 7(23):35169-80. Silva-Valenzuela CA, Desai PT, Molina-Quiroz RC, Pezoa D, Zhang Y, Porwollik S, Zhao M, Hoffman RM, Contreras I, Santiviago CA, McClelland M. PMID: 27145267; PMCID: PMC5085218.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    363. siRNA Targeting of MDR1 Reverses Multidrug Resistance in a Nude Mouse Model of Doxorubicin-resistant Human Hepatocellular Carcinoma. Anticancer Res. 2016 Jun; 36(6):2675-82. Yang H, Ding R, Tong Z, Huang J, Shen L, Sun YU, Liao J, Yang Z, Hoffman RM, Wang C, Meng X. PMID: 27272776.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    364. High efficacy of tumor-targeting Salmonella typhimurium A1-R on a doxorubicin- and dactolisib-resistant follicular dendritic-cell sarcoma in a patient-derived orthotopic xenograft PDOX nude mouse model. Oncotarget. 2016 May 31; 7(22):33046-54. Kiyuna T, Murakami T, Tome Y, Kawaguchi K, Igarashi K, Zhang Y, Zhao M, Li Y, Bouvet M, Kanaya F, Singh A, Dry S, Eilber FC, Hoffman RM. PMID: 27105519; PMCID: PMC5078074.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansAnimalsCells
    365. Tumor-specific cell-cycle decoy by Salmonella typhimurium A1-R combined with tumor-selective cell-cycle trap by methioninase overcome tumor intrinsic chemoresistance as visualized by FUCCI imaging. Cell Cycle. 2016 07 02; 15(13):1715-23. Yano S, Takehara K, Zhao M, Tan Y, Han Q, Li S, Bouvet M, Fujiwara T, Hoffman RM. PMID: 27152859; PMCID: PMC4957602.
      View in: PubMed   Mentions: 20  Translation:HumansAnimalsCells
    366. Imaging Nuclear-Cytoplasmic Dynamics in Primary and Metastatic Colon Cancer in Nude Mice. Anticancer Res. 2016 May; 36(5):2113-7. Hasegawa K, Suetsugu A, Nakamura M, Matsumoto T, Aoki H, Kunisada T, Bouvet M, Shimizu M, Hoffman RM. PMID: 27127111.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    367. Orthotopic Implantation of Intact Tumor Tissue Leads to Metastasis of OCUM-2MD3 Human Gastric Cancer in Nude Mice Visualized in Real Time by Intravital Fluorescence Imaging. Anticancer Res. 2016 May; 36(5):2125-30. Murakami T, Zhang Y, Wang X, Hiroshima Y, Kasashima H, Yashiro M, Hirakawa K, Miwa A, Kiyuna T, Matsuyama R, Tanaka K, Bouvet M, Endo I, Hoffman RM. PMID: 27127113.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    368. Therapeutic Efficacy of the Traditional Chinese Medicine Baishaoqiwu on TNBS-induced Colitis is Associated with Down-regulation of the TLR4/MyD88/NF-κB Signaling Pathway. In Vivo. 2016 May-Jun; 30(3):181-6. Xu X, Zhang L, Liu Z, Pan Y, Chen D, Yang Z, Deng Q, Cao X, Sun YU, Yang Z, Hoffman RM, Yuan H. PMID: 27107073.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    369. Bone Marrow Mesenchymal Stem Cells Reverse Liver Damage in a Carbon Tetrachloride-induced Mouse Model of Chronic Liver Injury. In Vivo. 2016 May-Jun; 30(3):187-93. Wang M, Zhang X, Xiong XI, Yang Z, Li P, Wang J, Sun YU, Yang Z, Hoffman RM. PMID: 27107074.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    370. Blockage of autophagy pathway enhances Salmonella tumor-targeting. Oncotarget. 2016 Apr 19; 7(16):22873-82. Liu B, Jiang Y, Dong T, Zhao M, Wu J, Li L, Chu Y, She S, Zhao H, Hoffman RM, Jia L. PMID: 27013582; PMCID: PMC5008408.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    371. Real-Time In Vivo Confocal Fluorescence Imaging of Prostate Cancer Bone-Marrow Micrometastasis Development at the Cellular Level in Nude Mice. J Cell Biochem. 2016 11; 117(11):2533-7. Miwa S, Toneri M, Igarashi K, Yano S, Kimura H, Hayashi K, Yamamoto N, Tsuchiya H, Hoffman RM. PMID: 26990763.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    372. Targeting the insulin growth factor-1 receptor with fluorescent antibodies enables high resolution imaging of human pancreatic cancer in orthotopic mouse models. Oncotarget. 2016 Apr 05; 7(14):18262-8. Park JY, Lee JY, Zhang Y, Hoffman RM, Bouvet M. PMID: 26919100; PMCID: PMC4951286.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    373. Adenoviral targeting of malignant melanoma for fluorescence-guided surgery prevents recurrence in orthotopic nude-mouse models. Oncotarget. 2016 Apr 05; 7(14):18558-72. Yano S, Takehara K, Kishimoto H, Urata Y, Kagawa S, Bouvet M, Fujiwara T, Hoffman RM. PMID: 26701857; PMCID: PMC4951309.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    374. Color-Coded Imaging of Syngeneic Orthotopic Malignant Lymphoma Interacting with Host Stromal Cells During Metastasis. Anticancer Res. 2016 Apr; 36(4):1473-8. Matsumoto T, Suetsugu A, Hasegawa K, Nakamura M, Aoki H, Kunisada T, Tsurumi H, Shimizu M, Hoffman RM. PMID: 27069122.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    375. Modified Liver Hanging Maneuver for En-bloc Right-sided Hepatectomy Combined with Total Caudate Lobectomy for Colon-Cancer Liver Metastasis and Hepatocellular Carcinoma. Anticancer Res. 2016 Apr; 36(4):1729-35. Hiroshima Y, Matsuo K, Kawaguchi D, Kikuchi Y, Endo I, Koda K, Togo S, Hoffman RM, Tanaka K. PMID: 27069152.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    376. Neddylation Inhibition Activates the Extrinsic Apoptosis Pathway through ATF4-CHOP-DR5 Axis in Human Esophageal Cancer Cells. Clin Cancer Res. 2016 Aug 15; 22(16):4145-57. Chen P, Hu T, Liang Y, Li P, Chen X, Zhang J, Ma Y, Hao Q, Wang J, Zhang P, Zhang Y, Zhao H, Yang S, Yu J, Jeong LS, Qi H, Yang M, Hoffman RM, Dong Z, Jia L. PMID: 26983464.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimalsCells
    377. Tumor-targeting Salmonella typhimurium A1-R in combination with doxorubicin eradicate soft tissue sarcoma in a patient-derived orthotopic xenograft (PDOX) model. Oncotarget. 2016 Mar 15; 7(11):12783-90. Murakami T, DeLong J, Eilber FC, Zhao M, Zhang Y, Zhang N, Singh A, Russell T, Deng S, Reynoso J, Quan C, Hiroshima Y, Matsuyama R, Chishima T, Tanaka K, Bouvet M, Chawla S, Endo I, Hoffman RM. PMID: 26859573; PMCID: PMC4914321.
      View in: PubMed   Mentions: 58     Fields:    Translation:HumansAnimalsCells
    378. Use of fluorescent proteins and color-coded imaging to visualize cancer cells with different genetic properties. Cancer Metastasis Rev. 2016 Mar; 35(1):5-19. Hoffman RM. PMID: 26942457.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    379. Decreased Expression of Tumor-suppressor Gene LKB1 Correlates with Poor Prognosis in Human Gastric Cancer. Anticancer Res. 2016 Mar; 36(3):869-75. Sun J, Ling B, Xu X, Ma R, Li G, Cao X, Ling W, Yang Z, Hoffman RM, Lu J. PMID: 26976973.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    380. Tumor relapse prevented by combining adoptive T cell therapy with Salmonella typhimurium. Oncoimmunology. 2016 Jun; 5(6):e1130207. Binder DC, Arina A, Wen F, Tu T, Zhao M, Hoffman RM, Wainwright DA, Schreiber H. PMID: 27471609; PMCID: PMC4938310.
      View in: PubMed   Mentions: 6  
    381. Improved Resection and Outcome of Colon-Cancer Liver Metastasis with Fluorescence-Guided Surgery Using In Situ GFP Labeling with a Telomerase-Dependent Adenovirus in an Orthotopic Mouse Model. PLoS One. 2016; 11(2):e0148760. Yano S, Takehara K, Miwa S, Kishimoto H, Hiroshima Y, Murakami T, Urata Y, Kagawa S, Bouvet M, Fujiwara T, Hoffman RM. PMID: 26849435; PMCID: PMC4743860.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    382. Surgical and Oncological Factors Affecting the Successful Engraftment of Patient-derived Xenografts in Pancreatic Ductal Adenocarcinoma. Anticancer Res. 2016 Feb; 36(2):517-21. Jun E, Jung J, Jeong SY, Choi EK, Kim MB, Lee JS, Hong SM, Seol HS, Hwang C, Hoffman RM, Shim IK, Chang S, Kim SC. PMID: 26851005.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    383. Fluorescence-guided surgery of human prostate cancer experimental bone metastasis in nude mice using anti-CEA DyLight 650 for tumor illumination. J Orthop Res. 2016 Apr; 34(4):559-65. Miwa S, De Magalhães N, Toneri M, Zhang Y, Cao W, Bouvet M, Tsuchiya H, Hoffman RM. PMID: 26135883.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    384. Fluorescent-Antibody Targeting of Insulin-Like Growth Factor-1 Receptor Visualizes Metastatic Human Colon Cancer in Orthotopic Mouse Models. PLoS One. 2016; 11(1):e0146504. Park JY, Murakami T, Lee JY, Zhang Y, Hoffman RM, Bouvet M. PMID: 26731105; PMCID: PMC4701661.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    385. Analysis of Two Complementary Single-Gene Deletion Mutant Libraries of Salmonella Typhimurium in Intraperitoneal Infection of BALB/c Mice. Front Microbiol. 2015; 6:1455. Silva-Valenzuela CA, Molina-Quiroz RC, Desai P, Valenzuela C, Porwollik S, Zhao M, Hoffman RM, Andrews-Polymenis H, Contreras I, Santiviago CA, McClelland M. PMID: 26779130; PMCID: PMC4700939.
      View in: PubMed   Mentions: 6  
    386. Tumor-Targeting Salmonella typhimurium A1-R: An Overview. Methods Mol Biol. 2016; 1409:1-8. Hoffman RM. PMID: 26846797.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    387. Methods for Tumor Targeting with Salmonella typhimurium A1-R. Methods Mol Biol. 2016; 1409:143-64. Hoffman RM, Zhao M. PMID: 26846809.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    388. Salmonella typhimurium A1-R and Cell-Cycle Decoy Therapy of Cancer. Methods Mol Biol. 2016; 1409:165-75. Hoffman RM, Yano S. PMID: 26846810.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    389. Future of Bacterial Therapy of Cancer. Methods Mol Biol. 2016; 1409:177-84. Hoffman RM. PMID: 26846811.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    390. Aging hair follicles rejuvenated by transplantation to a young subcutaneous environment. Cell Cycle. 2016; 15(8):1093-8. Cao W, Li L, Kajiura S, Amoh Y, Tan Y, Liu F, Hoffman RM. PMID: 26940664; PMCID: PMC4889257.
      View in: PubMed   Mentions: 2  Translation:AnimalsCells
    391. Isoproterenol directs hair follicle-associated pluripotent (HAP) stem cells to differentiate in vitro to cardiac muscle cells which can be induced to form beating heart-muscle tissue sheets. Cell Cycle. 2016; 15(5):760-5. Yamazaki A, Yashiro M, Mii S, Aki R, Hamada Y, Arakawa N, Kawahara K, Hoffman RM, Amoh Y. PMID: 27104748; PMCID: PMC4845933.
      View in: PubMed   Mentions: 12  Translation:AnimalsCells
    392. Introduction to Hair-Follicle-Associated Pluripotent Stem Cells. Methods Mol Biol. 2016; 1453:1-5. Hoffman RM. PMID: 27431240.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    393. Discovery of HAP Stem Cells. Methods Mol Biol. 2016; 1453:15-20. Li L, Hoffman RM. PMID: 27431242.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    394. Protocols for Ectopic Hair Growth from Transplanted Whisker Follicles on the Spinal Cord of Mice. Methods Mol Biol. 2016; 1453:137-44. Cao W, Liu F, Amoh Y, Hoffman RM. PMID: 27431253.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    395. Protocols for Efficient Differentiation of Hair Follicle-Associated Pluripotent (HAP) Stem Cells to Beating Cardiac Muscle Cells. Methods Mol Biol. 2016; 1453:151-9. Yashiro M, Mii S, Aki R, Hamada Y, Arakawa N, Kawahara K, Hoffman RM, Amoh Y. PMID: 27431255.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    396. Protocols for Cryopreservation of Intact Hair Follicle That Maintain Pluripotency of Nestin-Expressing Hair-Follicle-Associated Pluripotent (HAP) Stem Cells. Methods Mol Biol. 2016; 1453:173-8. Kajiura S, Mii S, Aki R, Hamada Y, Arakawa N, Kawahara K, Li L, Katsuoka K, Hoffman RM, Amoh Y. PMID: 27431257.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    397. Peripheral-Nerve and Spinal-Cord Regeneration in Mice Using Hair-Follicle-Associated Pluripotent (HAP) Stem Cells. Methods Mol Biol. 2016; 1453:21-32. Amoh Y, Katsuoka K, Hoffman RM. PMID: 27431243.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    398. Nestin-Expressing Hair-Follicle-Associated Pluripotent (HAP) Stem Cells Promote Whisker Sensory-Nerve Growth in Long-Term 3D-Gelfoam® Histoculture. Methods Mol Biol. 2016; 1453:39-47. Mii S, Duong J, Tome Y, Uchugonova A, Liu F, Amoh Y, Saito N, Katsuoka K, Hoffman RM. PMID: 27431245.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    399. Protocols for Gelfoam(®) Histoculture of Hair-Shaft-Producing Mouse Whisker Follicles Containing Nestin-GFP-Expressing Hair-Follicle-Associated Pluripotent (HAP) Stem Cells for Long Time Periods. Methods Mol Biol. 2016; 1453:145-50. Cao W, Liu F, Amoh Y, Hoffman RM. PMID: 27431254.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    400. Cryopreservation of Hair-Follicle Associated Pluripotent (HAP) Stem Cells Maintains Differentiation and Hair-Growth Potential. Adv Exp Med Biol. 2016; 951:191-198. Hoffman RM, Kajiura S, Cao W, Liu F, Amoh Y. PMID: 27837565.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    401. Extensive Hair Shaft Growth after Mouse Whisker Follicle Isolation, Cryopreservation and Transplantation in Nude Mice. PLoS One. 2015; 10(12):e0145997. Cao W, Li L, Tran B, Kajiura S, Amoh Y, Liu F, Hoffman RM. PMID: 26716690; PMCID: PMC4696652.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    402. Imaging the microenvironment of pancreatic cancer patient-derived orthotopic xenografts (PDOX) growing in transgenic nude mice expressing GFP, RFP, or CFP. Cancer Lett. 2016 09 28; 380(1):349-55. Hoffman RM, Bouvet M. PMID: 26742463.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    403. Adjuvant treatment with tumor-targeting Salmonella typhimurium A1-R reduces recurrence and increases survival after liver metastasis resection in an orthotopic nude mouse model. Oncotarget. 2015 Dec 08; 6(39):41856-62. Murakami T, Hiroshima Y, Zhao M, Zhang Y, Chishima T, Tanaka K, Bouvet M, Endo I, Hoffman RM. PMID: 26497690; PMCID: PMC4747193.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    404. Current status and future perspectives of fluorescence-guided surgery for cancer. Expert Rev Anticancer Ther. 2016; 16(1):71-81. DeLong JC, Hoffman RM, Bouvet M. PMID: 26567611; PMCID: PMC5572645.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimals
    405. Color-Coded Imaging of Breast Cancer Metastatic Niche Formation in Nude Mice. J Cell Biochem. 2015 Dec; 116(12):2730-4. Suetsugu A, Momiyama M, Hiroshima Y, Shimizu M, Saji S, Moriwaki H, Bouvet M, Hoffman RM. PMID: 25981355; PMCID: PMC4600030.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    406. Prostate Cancer Heterogeneous High-Metastatic Multi-Organ-Colonizing Chemo-Resistant Variants Selected by Serial Metastatic Passage in Nude Mice Are Highly Enriched for Multinucleate Giant Cells. PLoS One. 2015; 10(11):e0140721. Zhang L, Wu C, Hoffman RM. PMID: 26536025; PMCID: PMC4633180.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    407. Eradication of osteosarcoma by fluorescence-guided surgery with tumor labeling by a killer-reporter adenovirus. J Orthop Res. 2016 05; 34(5):836-44. Yano S, Miwa S, Kishimoto H, Urata Y, Tazawa H, Kagawa S, Bouvet M, Fujiwara T, Hoffman RM. PMID: 26479501.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    408. Recruitment of Cancer-Associated Fibroblasts and Blood Vessels by Orthotopic Liver Tumors Imaged in Red Fluorescent Protein (RFP) Transgenic Nude Mice. Anticancer Res. 2015 Nov; 35(11):5821-5. Suetsugu A, Hiroshima Y, Matsumoto T, Hasagawa K, Nakamura M, Shimizu M, Saji S, Moriwaki H, Bouvet M, Hoffman RM. PMID: 26504003.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    409. Real Time Metastatic Route Tracking of Orthotopic PC-3-GFP Human Prostate Cancer Using Intravital Imaging. J Cell Biochem. 2016 Apr; 117(4):1027-32. Zhang Y, Wang X, Hoffman RM, Seki N. PMID: 26515240.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    410. Tumor-targeting Salmonella typhimurium A1-R inhibits human prostate cancer experimental bone metastasis in mouse models. Oncotarget. 2015 Oct 13; 6(31):31335-43. Toneri M, Miwa S, Zhang Y, Hu C, Yano S, Matsumoto Y, Bouvet M, Nakanishi H, Hoffman RM, Zhao M. PMID: 26431498; PMCID: PMC4741609.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    411. Therapeutic efficacy of tumor-targeting Salmonella typhimurium A1-R on human colorectal cancer liver metastasis in orthotopic nude-mouse models. Oncotarget. 2015 Oct 13; 6(31):31368-77. Murakami T, Hiroshima Y, Zhao M, Zhang Y, Chishima T, Tanaka K, Bouvet M, Endo I, Hoffman RM. PMID: 26375054; PMCID: PMC4741612.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    412. Fluorescence-Guided Surgery of Liver Metastasis in Orthotopic Nude-Mouse Models. PLoS One. 2015; 10(10):e0138752. Murakami T, Hiroshima Y, Zhang Y, Chishima T, Tanaka K, Bouvet M, Endo I, Hoffman RM. PMID: 26427050; PMCID: PMC4591295.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    413. Imaging the Different Mechanisms of Prostate Cancer Cell-killing by Tumor-targeting Salmonella typhimurium A1-R. Anticancer Res. 2015 Oct; 35(10):5225-9. Uchugonova A, Zhang Y, Salz R, Liu F, Suetsugu A, Zhang L, Koenig K, Hoffman RM, Zhao M. PMID: 26408681.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    414. Extensive Hair-Shaft Elongation by Isolated Mouse Whisker Follicles in Very Long-Term Gelfoam® Histoculture. PLoS One. 2015; 10(9):e0138005. Cao W, Li L, Mii S, Amoh Y, Liu F, Hoffman RM. PMID: 26421923; PMCID: PMC4589329.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    415. Precise navigation surgery of tumours in the lung in mouse models enabled by in situ fluorescence labelling with a killer-reporter adenovirus. BMJ Open Respir Res. 2015; 2(1):e000096. Yano S, Zhang Y, Miwa S, Kishimoto H, Urata Y, Bouvet M, Kagawa S, Fujiwara T, Hoffman RM. PMID: 26380093; PMCID: PMC4567685.
      View in: PubMed   Mentions: 19  
    416. Surgically-Induced Multi-organ Metastasis in an Orthotopic Syngeneic Imageable Model of 4T1 Murine Breast Cancer. Anticancer Res. 2015 Sep; 35(9):4641-6. Zhang Y, Zhang N, Hoffman RM, Zhao M. PMID: 26254353.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    417. A Color-coded Imageable Syngeneic Mouse Model of Stromal-cell Recruitment by Metastatic Lymphoma. Anticancer Res. 2015 Sep; 35(9):4647-54. Matsumoto T, Suetsugu A, Shibata Y, Nakamura N, Aoki H, Kunisada T, Tsurumi H, Shimizu M, Hoffman RM. PMID: 26254354.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    418. Comparison of GFP-Expressing Imageable Mouse Models of Human Esophageal Squamous Cell Carcinoma Established in Various Anatomical Sites. Anticancer Res. 2015 Sep; 35(9):4655-63. Hu T, Qi H, Li P, Zhao G, Ma Y, Hao Q, Gao C, Zhang Y, Wang C, Yang M, Hoffman RM, Chen P, Dong Z. PMID: 26254355.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    419. Improved disease-free survival and overall survival after fluorescence-guided surgery of liver metastasis in an orthotopic nude mouse model. J Surg Oncol. 2015 Aug; 112(2):119-24. Murakami T, Hiroshima Y, Zhang Y, Bouvet M, Chishima T, Tanaka K, Endo I, Hoffman RM. PMID: 26266663.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    420. Long-Term Extensive Ectopic Hair Growth on the Spinal Cord of Mice from Transplanted Whisker Follicles. PLoS One. 2015; 10(8):e0133475. Cao W, Li L, Mii S, Amoh Y, Liu F, Hoffman RM. PMID: 26244638; PMCID: PMC4526646.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    421. Tumor-Targeting Salmonella typhimurium A1-R Arrests a Chemo-Resistant Patient Soft-Tissue Sarcoma in Nude Mice. PLoS One. 2015; 10(8):e0134324. Hiroshima Y, Zhao M, Zhang Y, Zhang N, Maawy A, Murakami T, Mii S, Uehara F, Yamamoto M, Miwa S, Yano S, Momiyama M, Mori R, Matsuyama R, Chishima T, Tanaka K, Ichikawa Y, Bouvet M, Endo I, Hoffman RM. PMID: 26237416; PMCID: PMC4523197.
      View in: PubMed   Mentions: 41     Fields:    Translation:AnimalsCells
    422. Patient-derived orthotopic xenografts: better mimic of metastasis than subcutaneous xenografts. Nat Rev Cancer. 2015 08; 15(8):451-2. Hoffman RM. PMID: 26422835.
      View in: PubMed   Mentions: 172     Fields:    Translation:HumansAnimals
    423. Real-time Non-invasive Spectral Imaging of Orthotopic Red Fluorescent Protein-expressing Lung Tumor Growth in Nude Mice. Anticancer Res. 2015 Jul; 35(7):3755-9. Zhang Y, Zhang N, Zhao M, Hoffman RM. PMID: 26124318.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    424. Comparison of the selective targeting efficacy of Salmonella typhimurium A1-R and VNP20009 on the Lewis lung carcinoma in nude mice. Oncotarget. 2015 Jun 10; 6(16):14625-31. Zhang Y, Zhang N, Zhao M, Hoffman RM. PMID: 25714030; PMCID: PMC4546492.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    425. Tumor-Targeting Salmonella typhimurium A1-R in Combination with Trastuzumab Eradicates HER-2-Positive Cervical Cancer Cells in Patient-Derived Mouse Models. PLoS One. 2015; 10(6):e0120358. Hiroshima Y, Zhang Y, Zhao M, Zhang N, Murakami T, Maawy A, Mii S, Uehara F, Yamamoto M, Miwa S, Yano S, Momiyama M, Mori R, Matsuyama R, Chishima T, Tanaka K, Ichikawa Y, Bouvet M, Endo I, Hoffman RM. PMID: 26047477; PMCID: PMC4457918.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    426. Combination Efficacy of Astragalus membranaceus and Curcuma wenyujin at Different Stages of Tumor Progression in an Imageable Orthotopic Nude Mouse Model of Metastatic Human Ovarian Cancer Expressing Red Fluorescent Protein. Anticancer Res. 2015 Jun; 35(6):3193-207. Yin G, Tang D, Dai J, Liu M, Wu M, Sun YU, Yang Z, Hoffman RM, Li L, Zhang S, Guo X. PMID: 26026079.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    427. Targeting tumors with a killer-reporter adenovirus for curative fluorescence-guided surgery of soft-tissue sarcoma. Oncotarget. 2015 May 30; 6(15):13133-48. Yano S, Miwa S, Kishimoto H, Uehara F, Tazawa H, Toneri M, Hiroshima Y, Yamamoto M, Urata Y, Kagawa S, Bouvet M, Fujiwara T, Hoffman RM. PMID: 26033451; PMCID: PMC4537004.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    428. Drug exposure in a metastatic human lung adenocarcinoma cell line gives rise to cells with differing adhesion, proliferation, and gene expression: Implications for cancer chemotherapy. Mol Med Rep. 2015 Sep; 12(3):3236-3242. Li H, He J, Zhong N, Hoffman RM. PMID: 26004767; PMCID: PMC4526089.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    429. From hair to heart: nestin-expressing hair-follicle-associated pluripotent (HAP) stem cells differentiate to beating cardiac muscle cells. Cell Cycle. 2015; 14(14):2362-6. Yashiro M, Mii S, Aki R, Hamada Y, Arakawa N, Kawahara K, Hoffman RM, Amoh Y. PMID: 25970547; PMCID: PMC4614865.
      View in: PubMed   Mentions: 22  Translation:HumansAnimalsCells
    430. Intraperitoneal administration of tumor-targeting Salmonella typhimurium A1-R inhibits disseminated human ovarian cancer and extends survival in nude mice. Oncotarget. 2015 May 10; 6(13):11369-77. Matsumoto Y, Miwa S, Zhang Y, Zhao M, Yano S, Uehara F, Yamamoto M, Hiroshima Y, Toneri M, Bouvet M, Matsubara H, Tsuchiya H, Hoffman RM. PMID: 25957417; PMCID: PMC4484462.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    431. Imaging the Interaction of Pancreatic Cancer and Stellate Cells in the Tumor Microenvironment during Metastasis. Anticancer Res. 2015 May; 35(5):2545-51. Suetsugu A, Snyder CS, Moriwaki H, Saji S, Bouvet M, Hoffman RM. PMID: 25964528.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    432. Nanoparticle albumin-bound-paclitaxel: a limited improvement under the current therapeutic paradigm of pancreatic cancer. Expert Opin Pharmacother. 2015 May; 16(7):943-7. Hoffman RM, Bouvet M. PMID: 25887245; PMCID: PMC5559227.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    433. Toward Curative Fluorescence-Guided Surgery of Pancreatic Cancer. Hepatogastroenterology. 2015 May; 62(139):715-22. Bouvet M, Hoffman RM. PMID: 26897960.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    434. Early Reporting of Apoptosis by Real-time Imaging of Cancer Cells Labeled with Green Fluorescent Protein in the Nucleus and Red Fluorescent Protein in the Cytoplasm. Anticancer Res. 2015 May; 35(5):2539-43. Yang M, Jiang P, Hoffman RM. PMID: 25964527.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    435. The Use of Living Cancer Cells Expressing Green Fluorescent Protein in the Nucleus and Red Fluorescence Protein in the Cytoplasm for Real-time Confocal Imaging of Chromosome and Cytoplasmic Dynamics During Mitosis. Anticancer Res. 2015 May; 35(5):2553-7. Suetsugu A, Jiang P, Yang M, Yamamoto N, Moriwaki H, Saji S, Hoffman RM. PMID: 25964529.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    436. Experimental Curative Fluorescence-guided Surgery of Highly Invasive Glioblastoma Multiforme Selectively Labeled With a Killer-reporter Adenovirus. Mol Ther. 2015 Jul; 23(7):1182-1188. Yano S, Miwa S, Kishimoto H, Toneri M, Hiroshima Y, Yamamoto M, Bouvet M, Urata Y, Tazawa H, Kagawa S, Fujiwara T, Hoffman RM. PMID: 25896244; PMCID: PMC4817790.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    437. Synergistic inhibition of autophagy and neddylation pathways as a novel therapeutic approach for targeting liver cancer. Oncotarget. 2015 Apr 20; 6(11):9002-17. Chen P, Hu T, Liang Y, Jiang Y, Pan Y, Li C, Zhang P, Wei D, Li P, Jeong LS, Chu Y, Qi H, Yang M, Hoffman RM, Dong Z, Jia L. PMID: 25797246; PMCID: PMC4496198.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    438. Photoimmunotherapy Inhibits Tumor Recurrence After Surgical Resection on a Pancreatic Cancer Patient-Derived Orthotopic Xenograft (PDOX) Nude Mouse Model. Ann Surg Oncol. 2015 Dec; 22 Suppl 3:S1469-74. Hiroshima Y, Maawy A, Zhang Y, Guzman MG, Heim R, Makings L, Luiken GA, Kobayashi H, Tanaka K, Endo I, Hoffman RM, Bouvet M. PMID: 25893411; PMCID: PMC7711336.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    439. Cryopreservation of the Hair Follicle Maintains Pluripotency of Nestin-Expressing Hair Follicle-Associated Pluripotent Stem Cells. Tissue Eng Part C Methods. 2015 Aug; 21(8):825-31. Kajiura S, Mii S, Aki R, Hamada Y, Arakawa N, Kawahara K, Li L, Katsuoka K, Hoffman RM, Amoh Y. PMID: 25743086; PMCID: PMC4523096.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    440. Real-time fluorescence imaging of the DNA damage repair response during mitosis. J Cell Biochem. 2015 Apr; 116(4):661-6. Miwa S, Yano S, Yamamoto M, Matsumoto Y, Uehara F, Hiroshima Y, Toneri M, Murakami T, Kimura H, Hayashi K, Yamamoto N, Efimova EV, Tsuchiya H, Hoffman RM. PMID: 25418288.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    441. MUC1 selectively targets human pancreatic cancer in orthotopic nude mouse models. PLoS One. 2015; 10(3):e0122100. Park JY, Hiroshima Y, Lee JY, Maawy AA, Hoffman RM, Bouvet M. PMID: 25815753; PMCID: PMC4376872.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    442. Near infra-red photoimmunotherapy with anti-CEA-IR700 results in extensive tumor lysis and a significant decrease in tumor burden in orthotopic mouse models of pancreatic cancer. PLoS One. 2015; 10(3):e0121989. Maawy AA, Hiroshima Y, Zhang Y, Heim R, Makings L, Garcia-Guzman M, Luiken GA, Kobayashi H, Hoffman RM, Bouvet M. PMID: 25799218; PMCID: PMC4370703.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    443. Traditional Chinese medicine herbal mixture LQ arrests FUCCI-expressing HeLa cells in G₀/G₁ phase in 2D plastic, 2.5D Matrigel, and 3D Gelfoam culture visualized with FUCCI imaging. Oncotarget. 2015 Mar 10; 6(7):5292-8. Zhang L, Wu C, Bouvet M, Yano S, Hoffman RM. PMID: 25779660; PMCID: PMC4467149.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    444. Fluorescence-guided surgery, but not bright-light surgery, prevents local recurrence in a pancreatic cancer patient derived orthotopic xenograft (PDOX) model resistant to neoadjuvant chemotherapy (NAC). Pancreatology. 2015 May-Jun; 15(3):295-301. Hiroshima Y, Maawy A, Zhang Y, Murakami T, Momiyama M, Mori R, Matsuyama R, Chishima T, Tanaka K, Ichikawa Y, Endo I, Hoffman RM, Bouvet M. PMID: 25800176; PMCID: PMC4446223.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimals
    445. Nestin-expressing hair follicle-accessible pluripotent stem cells for nerve and spinal cord repair. Cells Tissues Organs. 2014; 200(1):42-47. Hoffman RM. PMID: 25766743.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    446. Fluorescence-guided surgery: it is the cure that matters: in reply to Giorgakis and colleagues. J Am Coll Surg. 2015 Mar; 220(3):377-9. Bouvet M, Hoffman RM. PMID: 25700908.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    447. Fluorescence-guided surgery of retroperitoneal-implanted human fibrosarcoma in nude mice delays or eliminates tumor recurrence and increases survival compared to bright-light surgery. PLoS One. 2015; 10(2):e0116865. Uehara F, Hiroshima Y, Miwa S, Tome Y, Yano S, Yamamoto M, Matsumoto Y, Maehara H, Tanaka K, Bouvet M, Kanaya F, Hoffman RM. PMID: 25710463; PMCID: PMC4339719.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    448. Tumor-targeting Salmonella typhimurium A1-R arrests growth of breast-cancer brain metastasis. Oncotarget. 2015 Feb 20; 6(5):2615-22. Zhang Y, Miwa S, Zhang N, Hoffman RM, Zhao M. PMID: 25575815; PMCID: PMC4413605.
      View in: PubMed   Mentions: 35     Fields:    Translation:AnimalsCells
    449. Photoimmunotherapy lowers recurrence after pancreatic cancer surgery in orthotopic nude mouse models. J Surg Res. 2015 Jul; 197(1):5-11. Maawy AA, Hiroshima Y, Zhang Y, Garcia-Guzman M, Luiken GA, Kobayashi H, Hoffman RM, Bouvet M. PMID: 25799527; PMCID: PMC4457622.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    450. Establishment of a patient-derived orthotopic Xenograft (PDOX) model of HER-2-positive cervical cancer expressing the clinical metastatic pattern. PLoS One. 2015; 10(2):e0117417. Hiroshima Y, Zhang Y, Zhang N, Maawy A, Mii S, Yamamoto M, Uehara F, Miwa S, Yano S, Murakami T, Momiyama M, Chishima T, Tanaka K, Ichikawa Y, Bouvet M, Murata T, Endo I, Hoffman RM. PMID: 25689852; PMCID: PMC4331082.
      View in: PubMed   Mentions: 56     Fields:    Translation:HumansAnimals
    451. Application of GFP imaging in cancer. Lab Invest. 2015 Apr; 95(4):432-52. Hoffman RM. PMID: 25686095; PMCID: PMC4383682.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    452. Complementarity of variable-magnification and spectral-separation fluorescence imaging systems for noninvasive detection of metastasis and intravital detection of single cancer cells in mouse models. Anticancer Res. 2015 Feb; 35(2):661-7. Zhang Y, Hiroshima Y, Ma H, Zhang N, Zhao M, Hoffman RM. PMID: 25667443.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    453. Patient-derived orthotopic xenograft (PDOX) nude mouse model of soft-tissue sarcoma more closely mimics the patient behavior in contrast to the subcutaneous ectopic model. Anticancer Res. 2015 Feb; 35(2):697-701. Hiroshima Y, Zhang Y, Zhang N, Uehara F, Maawy A, Murakami T, Mii S, Yamamoto M, Miwa S, Yano S, Momiyama M, Mori R, Matsuyama R, Chishima T, Tanaka K, Ichikawa Y, Bouvet M, Endo I, Hoffman RM. PMID: 25667448.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansAnimals
    454. Cancer cells mimic in vivo spatial-temporal cell-cycle phase distribution and chemosensitivity in 3-dimensional Gelfoam® histoculture but not 2-dimensional culture as visualized with real-time FUCCI imaging. Cell Cycle. 2015; 14(6):808-19. Yano S, Miwa S, Mii S, Hiroshima Y, Uehara F, Kishimoto H, Tazawa H, Zhao M, Bouvet M, Fujiwara T, Hoffman RM. PMID: 25564963; PMCID: PMC4614530.
      View in: PubMed   Mentions: 13  Translation:HumansAnimalsCells
    455. Tumor imaging technologies in mouse models. Methods Mol Biol. 2015; 1267:321-48. Bouvet M, Hoffman RM. PMID: 25636477.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    456. Cell-cycle fate-monitoring distinguishes individual chemosensitive and chemoresistant cancer cells in drug-treated heterogeneous populations demonstrated by real-time FUCCI imaging. Cell Cycle. 2015; 14(4):621-9. Miwa S, Yano S, Kimura H, Yamamoto M, Toneri M, Matsumoto Y, Uehara F, Hiroshima Y, Murakami T, Hayashi K, Yamamoto N, Bouvet M, Fujiwara T, Tsuchiya H, Hoffman RM. PMID: 25551170; PMCID: PMC4613186.
      View in: PubMed   Mentions: 14  Translation:HumansCells
    457. Heterogeneous cell-cycle behavior in response to UVB irradiation by a population of single cancer cells visualized by time-lapse FUCCI imaging. Cell Cycle. 2015; 14(12):1932-7. Miwa S, Yano S, Kimura H, Yamamoto M, Toneri M, Murakami T, Hayashi K, Yamamoto N, Fujiwara T, Tsuchiya H, Hoffman RM. PMID: 25946083; PMCID: PMC4615034.
      View in: PubMed   Mentions: 2  Translation:HumansCells
    458. Back to the Future: Are Tumor-Targeting Bacteria the Next-Generation Cancer Therapy? Methods Mol Biol. 2015; 1317:239-60. Hoffman RM. PMID: 26072411.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    459. Comparison of label-free and GFP multiphoton imaging of hair follicle-associated pluripotent (HAP) stem cells in mouse whiskers. Cell Cycle. 2015; 14(21):3430-3. Uchugonova A, Cao W, Hoffman RM, Koenig K. PMID: 26397024; PMCID: PMC4825630.
      View in: PubMed   Mentions: 2  Translation:AnimalsCells
    460. Inhibition of spontaneous and experimental lung metastasis of soft-tissue sarcoma by tumor-targeting Salmonella typhimurium A1-R. Oncotarget. 2014 Dec 30; 5(24):12849-61. Miwa S, Zhang Y, Baek KE, Uehara F, Yano S, Yamamoto M, Hiroshima Y, Matsumoto Y, Kimura H, Hayashi K, Yamamoto N, Bouvet M, Tsuchiya H, Hoffman RM, Zhao M. PMID: 25528763; PMCID: PMC4350333.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    461. Biological ablation of sentinel lymph node metastasis in submucosally invaded early gastrointestinal cancer. Mol Ther. 2015 Mar; 23(3):501-9. Kikuchi S, Kishimoto H, Tazawa H, Hashimoto Y, Kuroda S, Nishizaki M, Nagasaka T, Shirakawa Y, Kagawa S, Urata Y, Hoffman RM, Fujiwara T. PMID: 25523761; PMCID: PMC4351467.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    462. Efficacy of tumor-targeting Salmonella typhimurium A1-R in combination with anti-angiogenesis therapy on a pancreatic cancer patient-derived orthotopic xenograft (PDOX) and cell line mouse models. Oncotarget. 2014 Dec 15; 5(23):12346-57. Hiroshima Y, Zhang Y, Murakami T, Maawy A, Miwa S, Yamamoto M, Yano S, Sato S, Momiyama M, Mori R, Matsuyama R, Chishima T, Tanaka K, Ichikawa Y, Bouvet M, Endo I, Zhao M, Hoffman RM. PMID: 25402324; PMCID: PMC4322966.
      View in: PubMed   Mentions: 70     Fields:    Translation:HumansAnimalsCells
    463. Development of recombinant methioninase to target the general cancer-specific metabolic defect of methionine dependence: a 40-year odyssey. Expert Opin Biol Ther. 2015 Jan; 15(1):21-31. Hoffman RM. PMID: 25439528.