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David Traver

Title(s)Adjunct Professor, Cell and Developmental Biology
SchoolVc-academic Affairs
Address9500 Gilman Drive #
La Jolla CA 92093
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    Collapse Research 
    Collapse research activities and funding
    The role of macrophages during hematopoietic stem cell emergence
    NIH R21AI137575Nov 19, 2018 - Oct 31, 2020
    Role: Principal Investigator
    An integrative cellular blueprint of vertebrate tissue development
    NIH R01OD026219Sep 15, 2018 - Aug 31, 2023
    Role: Principal Investigator
    Wnt signaling in hematopoietic development
    NIH R01HL135205Jan 1, 2017 - Jun 30, 2025
    Role: Principal Investigator
    Lineage tracing the embryonic origins of tissue-resident macrophages
    NIH R21AI124179Jun 17, 2016 - May 31, 2018
    Role: Principal Investigator
    FGF signaling in the specification and emergence of hematopoietic stem cells
    NIH R01HL119056Aug 1, 2014 - Apr 30, 2018
    Role: Principal Investigator
    Ontogeny and function of zebrafish antigen presenting cells
    NIH R56AI079287Aug 15, 2011 - Mar 31, 2013
    Role: Principal Investigator
    Molecular and functional dissection of the zebrafish hematopoietic stem cell niche
    NIH R01DK074482May 8, 2006 - Nov 30, 2024
    Role: Principal Investigator
    Study of hematopoietic stem cells in zebrafish
    NIH K01DK066254Feb 15, 2004 - Dec 31, 2008
    Role: Principal Investigator
    IVEM and Image Analysis Resource
    NIH P41RR004050Dec 12, 1988 - Mar 31, 2014
    Role: Co-Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Multimodal Investigation of Angiogenesis and Its Prevention by Small Compounds in a Zebrafish Cancer Model. Adv Sci (Weinh). 2025 Sep; 12(33):e15176. Andreana M, Sentosa R, Sturtzel C, Pfister M, Werkmeister R, Schmitt A, Traver D, Leitgeb R, Drexler W, Distel M, Unterhuber A. PMID: 40557748; PMCID: PMC12412526.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    2. T-Lymphoblastic Lymphoma Cells Express High Levels of BCL2, S1P1, and ICAM1, Leading to a Blockade of Tumor Cell Intravasation. Cancer Cell. 2024 Jun 10; 42(6):1130-1131. Feng H, Stachura DL, White RM, Gutierrez A, Zhang L, Sanda T, Jette CA, Testa JR, Neuberg DS, Langenau DM, Kutok JL, Zon LI, Traver D, Fleming MD, Kanki JP, Look AT. PMID: 38861925; PMCID: PMC11253892.
      View in: PubMed   Mentions: 1     Fields:    
    3. A multistep computational approach reveals a neuro-mesenchymal cell population in the embryonic hematopoietic stem cell niche. Development. 2024 Apr 01; 151(7). Miladinovic O, Canto PY, Pouget C, Piau O, Radic N, Freschu P, Megherbi A, Brujas Prats C, Jacques S, Hirsinger E, Geeverding A, Dufour S, Petit L, Souyri M, North T, Isambert H, Traver D, Jaffredo T, Charbord P, Durand C. PMID: 38451068; PMCID: PMC11057820.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    4. Comparative transcriptomics coupled to developmental grading via transgenic zebrafish reporter strains identifies conserved features in neutrophil maturation. Nat Commun. 2024 Feb 27; 15(1):1792. Kirchberger S, Shoeb MR, Lazic D, Wenninger-Weinzierl A, Fischer K, Shaw LE, Nogueira F, Rifatbegovic F, Bozsaky E, Ladenstein R, Bodenmiller B, Lion T, Traver D, Farlik M, Schöfer C, Taschner-Mandl S, Halbritter F, Distel M. PMID: 38413586; PMCID: PMC10899643.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    5. Human pallial MGE-type GABAergic interneuron cell therapy for chronic focal epilepsy. Cell Stem Cell. 2023 10 05; 30(10):1331-1350.e11. Bershteyn M, Bröer S, Parekh M, Maury Y, Havlicek S, Kriks S, Fuentealba L, Lee S, Zhou R, Subramanyam G, Sezan M, Sevilla ES, Blankenberger W, Spatazza J, Zhou L, Nethercott H, Traver D, Hampel P, Kim H, Watson M, Salter N, Nesterova A, Au W, Kriegstein A, Alvarez-Buylla A, Rubenstein J, Banik G, Bulfone A, Priest C, Nicholas CR. PMID: 37802038; PMCID: PMC10993865.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    6. Dermomyotome-derived endothelial cells migrate to the dorsal aorta to support hematopoietic stem cell emergence. Elife. 2023 09 11; 12. Sahai-Hernandez P, Pouget C, Eyal S, Svoboda O, Chacon J, Grimm L, Gjøen T, Traver D. PMID: 37695317; PMCID: PMC10495111.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    7. Systemic Inflammation and Normocytic Anemia in DOCK11 Deficiency. N Engl J Med. 2023 08 10; 389(6):527-539. Block J, Rashkova C, Castanon I, Zoghi S, Platon J, Ardy RC, Fujiwara M, Chaves B, Schoppmeyer R, van der Made CI, Jimenez Heredia R, Harms FL, Alavi S, Alsina L, Sanchez Moreno P, Ávila Polo R, Cabrera-Pérez R, Kostel Bal S, Pfajfer L, Ransmayr B, Mautner AK, Kondo R, Tinnacher A, Caldera M, Schuster M, Domínguez Conde C, Platzer R, Salzer E, Boyer T, Brunner HG, Nooitgedagt-Frons JE, Iglesias E, Deyà-Martinez A, Camacho-Lovillo M, Menche J, Bock C, Huppa JB, Pickl WF, Distel M, Yoder JA, Traver D, Engelhardt KR, Linden T, Kager L, Hannich JT, Hoischen A, Hambleton S, Illsinger S, Da Costa L, Kutsche K, Chavoshzadeh Z, van Buul JD, Antón J, Calzada-Hernández J, Neth O, Viaud J, Nishikimi A, Dupré L, Boztug K. PMID: 37342957.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    8. Long noncoding RNA HIKER regulates erythropoiesis in Monge's disease via CSNK2B. J Clin Invest. 2023 06 01; 133(11). Azad P, Zhou D, Tu HC, Villafuerte FC, Traver D, Rana TM, Haddad GG. PMID: 37022795; PMCID: PMC10231995.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    9. The sinusoidal hematopoietic niche is formed by Jam1a via Notch signaling in the zebrafish kidney. iScience. 2023 Apr 21; 26(4):106508. Kondo M, Kimura K, Kobayashi-Sun J, Yamamori S, Taniguchi M, Traver D, Kobayashi I. PMID: 37123221; PMCID: PMC10139997.
      View in: PubMed   Mentions: 1  
    10. Notch signaling enhances bone regeneration in the zebrafish mandible. Development. 2022 03 01; 149(5). Kraus JM, Giovannone D, Rydzik R, Balsbaugh JL, Moss IL, Schwedler JL, Bertrand JY, Traver D, Hankenson KD, Crump JG, Youngstrom DW. PMID: 35178545; PMCID: PMC8959151.
      View in: PubMed   Mentions: 16     Fields:    Translation:Animals
    11. Endothelial struts enable the generation of large lumenized blood vessels de novo. Nat Cell Biol. 2021 04; 23(4):322-329. Weijts B, Shaked I, Ginsberg M, Kleinfeld D, Robin C, Traver D. PMID: 33837285; PMCID: PMC8500358.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    12. A zebrafish model of granulin deficiency reveals essential roles in myeloid cell differentiation. Blood Adv. 2021 02 09; 5(3):796-811. Campbell CA, Fursova O, Cheng X, Snella E, McCune A, Li L, Solchenberger B, Schmid B, Sahoo D, Morton M, Traver D, Espín-Palazón R. PMID: 33560393; PMCID: PMC7876888.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimals
    13. Zebrafish Kit ligands cooperate with erythropoietin to promote erythroid cell expansion. Blood Adv. 2020 12 08; 4(23):5915-5924. Oltova J, Svoboda O, Machonova O, Svatonova P, Traver D, Kolar M, Bartunek P. PMID: 33259600; PMCID: PMC7724902.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    14. Haematopoietic stem cell-dependent Notch transcription is mediated by p53 through the Histone chaperone Supt16h. Nat Cell Biol. 2020 12; 22(12):1411-1422. Espanola SG, Song H, Ryu E, Saxena A, Kim ES, Manegold JE, Nasamran CA, Sahoo D, Oh CK, Bickers C, Shin U, Grainger S, Park YH, Pandolfo L, Kang MS, Kang S, Myung K, Cooper KL, Yelon D, Traver D, Lee Y. PMID: 33230303; PMCID: PMC8092813.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    15. Impact of COVID-19 on early career scientists: an optimistic guide for the future. BMC Biol. 2020 07 30; 18(1):95. Termini CM, Traver D. PMID: 32731867; PMCID: PMC7391227.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansPHPublic Health
    16. Evaluation of the Cunningham Panel™ in pediatric autoimmune neuropsychiatric disorder associated with streptococcal infection (PANDAS) and pediatric acute-onset neuropsychiatric syndrome (PANS): Changes in antineuronal antibody titers parallel changes in patient symptoms. J Neuroimmunol. 2020 02 15; 339:577138. Shimasaki C, Frye RE, Trifiletti R, Cooperstock M, Kaplan G, Melamed I, Greenberg R, Katz A, Fier E, Kem D, Traver D, Dempsey T, Latimer ME, Cross A, Dunn JP, Bentley R, Alvarez K, Reim S, Appleman J. PMID: 31884258.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    17. Enrichment of hematopoietic stem/progenitor cells in the zebrafish kidney. Sci Rep. 2019 10 02; 9(1):14205. Kobayashi I, Kondo M, Yamamori S, Kobayashi-Sun J, Taniguchi M, Kanemaru K, Katakura F, Traver D. PMID: 31578390; PMCID: PMC6775131.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    18. Direct Visualization of Live Zebrafish Glycans via Single-Step Metabolic Labeling with Fluorophore-Tagged Nucleotide Sugars. Angew Chem Int Ed Engl. 2019 10 01; 58(40):14327-14333. Hong S, Sahai-Hernandez P, Chapla DG, Moremen KW, Traver D, Wu P. PMID: 31295389; PMCID: PMC6820142.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    19. EGFR is required for Wnt9a-Fzd9b signalling specificity in haematopoietic stem cells. Nat Cell Biol. 2019 06; 21(6):721-730. Grainger S, Nguyen N, Richter J, Setayesh J, Lonquich B, Oon CH, Wozniak JM, Barahona R, Kamei CN, Houston J, Carrillo-Terrazas M, Drummond IA, Gonzalez D, Willert K, Traver D. PMID: 31110287; PMCID: PMC6559346.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansAnimalsCells
    20. Embryonic Immune Cells Remodel the Heart. Dev Cell. 2019 03 11; 48(5):595-596. Grainger S, Traver D. PMID: 30861372.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    21. AIBP-mediated cholesterol efflux instructs hematopoietic stem and progenitor cell fate. Science. 2019 03 08; 363(6431):1085-1088. Gu Q, Yang X, Lv J, Zhang J, Xia B, Kim JD, Wang R, Xiong F, Meng S, Clements TP, Tandon B, Wagner DS, Diaz MF, Wenzel PL, Miller YI, Traver D, Cooke JP, Li W, Zon LI, Chen K, Bai Y, Fang L. PMID: 30705153; PMCID: PMC6469354.
      View in: PubMed   Mentions: 76     Fields:    Translation:AnimalsCells
    22. Blood flow-induced Notch activation and endothelial migration enable vascular remodeling in zebrafish embryos. Nat Commun. 2018 12 14; 9(1):5314. Weijts B, Gutierrez E, Saikin SK, Ablooglu AJ, Traver D, Groisman A, Tkachenko E. PMID: 30552331; PMCID: PMC6294260.
      View in: PubMed   Mentions: 43     Fields:    Translation:AnimalsCells
    23. Zebrafish snai2 mutants fail to phenocopy morphant phenotypes. PLoS One. 2018; 13(9):e0202747. Bickers C, Española SD, Grainger S, Pouget C, Traver D. PMID: 30208064; PMCID: PMC6135377.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    24. Embryonic Microglia Derive from Primitive Macrophages and Are Replaced by cmyb-Dependent Definitive Microglia in Zebrafish. Cell Rep. 2018 07 03; 24(1):130-141. Ferrero G, Mahony CB, Dupuis E, Yvernogeau L, Di Ruggiero E, Miserocchi M, Caron M, Robin C, Traver D, Bertrand JY, Wittamer V. PMID: 29972775.
      View in: PubMed   Mentions: 55     Fields:    Translation:AnimalsCells
    25. Lipoprotein lipase regulates hematopoietic stem progenitor cell maintenance through DHA supply. Nat Commun. 2018 04 03; 9(1):1310. Liu C, Han T, Stachura DL, Wang H, Vaisman BL, Kim J, Klemke RL, Remaley AT, Rana TM, Traver D, Miller YI. PMID: 29615667; PMCID: PMC5882990.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    26. WNT9A Is a Conserved Regulator of Hematopoietic Stem and Progenitor Cell Development. Genes (Basel). 2018 Jan 29; 9(2). Richter J, Stanley EG, Ng ES, Elefanty AG, Traver D, Willert K. PMID: 29382179; PMCID: PMC5852562.
      View in: PubMed   Mentions: 12     Fields:    
    27. Wnt Signaling in Hematological Malignancies. Prog Mol Biol Transl Sci. 2018 01; 153:321-341. Grainger S, Traver D, Willert K. PMID: 29389522; PMCID: PMC5972548.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    28. Mecp2 regulates tnfa during zebrafish embryonic development and acute inflammation. Dis Model Mech. 2017 12 19; 10(12):1439-1451. van der Vaart M, Svoboda O, Weijts BG, Espín-Palazón R, Sapp V, Pietri T, Bagnat M, Muotri AR, Traver D. PMID: 28993314; PMCID: PMC5769600.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    29. Proinflammatory Signals as Fuel for the Fire of Hematopoietic Stem Cell Emergence. Trends Cell Biol. 2018 01; 28(1):58-66. Espin-Palazon R, Weijts B, Mulero V, Traver D. PMID: 28882414.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansAnimalsCells
    30. The role of Wnt signaling in hematopoietic stem cell development. Crit Rev Biochem Mol Biol. 2017 08; 52(4):414-424. Richter J, Traver D, Willert K. PMID: 28508727; PMCID: PMC6104630.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansAnimalsCells
    31. The Pu.1 target gene Zbtb11 regulates neutrophil development through its integrase-like HHCC zinc finger. Nat Commun. 2017 04 06; 8:14911. Keightley MC, Carradice DP, Layton JE, Pase L, Bertrand JY, Wittig JG, Dakic A, Badrock AP, Cole NJ, Traver D, Nutt SL, McCoey J, Buckle AM, Heath JK, Lieschke GJ. PMID: 28382966; PMCID: PMC5384227.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    32. Zebrafish Caudal Haematopoietic Embryonic Stromal Tissue (CHEST) Cells Support Haematopoiesis. Sci Rep. 2017 03 16; 7:44644. Wolf A, Aggio J, Campbell C, Wright F, Marquez G, Traver D, Stachura DL. PMID: 28300168; PMCID: PMC5353684.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    33. Corrigendum: Clonal fate mapping quantifies the number of haematopoietic stem cells that arise during development. Nat Cell Biol. 2017 01 31; 19(2):142. Henninger J, Santoso B, Hans S, Durand E, Moore J, Mosimann C, Brand M, Traver D, Zon L. PMID: 28139650; PMCID: PMC5898623.
      View in: PubMed   Mentions: 42     Fields:    
    34. A Four-Well Dish for High-Resolution Longitudinal Imaging of the Tail and Posterior Trunk of Larval Zebrafish. Zebrafish. 2017 10; 14(5):489-491. Weijts B, Tkachenko E, Traver D, Groisman A. PMID: 28118101; PMCID: PMC5650709.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    35. Biallelic mutations in the 3' exonuclease TOE1 cause pontocerebellar hypoplasia and uncover a role in snRNA processing. Nat Genet. 2017 Mar; 49(3):457-464. Lardelli RM, Schaffer AE, Eggens VR, Zaki MS, Grainger S, Sathe S, Van Nostrand EL, Schlachetzki Z, Rosti B, Akizu N, Scott E, Silhavy JL, Heckman LD, Rosti RO, Dikoglu E, Gregor A, Guemez-Gamboa A, Musaev D, Mande R, Widjaja A, Shaw TL, Markmiller S, Marin-Valencia I, Davies JH, de Meirleir L, Kayserili H, Altunoglu U, Freckmann ML, Warwick L, Chitayat D, Blaser S, Çaglayan AO, Bilguvar K, Per H, Fagerberg C, Christesen HT, Kibaek M, Aldinger KA, Manchester D, Matsumoto N, Muramatsu K, Saitsu H, Shiina M, Ogata K, Foulds N, Dobyns WB, Chi NC, Traver D, Spaccini L, Bova SM, Gabriel SB, Gunel M, Valente EM, Nassogne MC, Bennett EJ, Yeo GW, Baas F, Lykke-Andersen J, Gleeson JG. PMID: 28092684; PMCID: PMC5325768.
      View in: PubMed   Mentions: 51     Fields:    Translation:HumansAnimalsCells
    36. Comparative Analysis of Vertebrate Diurnal/Circadian Transcriptomes. PLoS One. 2017; 12(1):e0169923. Boyle G, Richter K, Priest HD, Traver D, Mockler TC, Chang JT, Kay SA, Breton G. PMID: 28076377; PMCID: PMC5226840.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    37. Clonal fate mapping quantifies the number of haematopoietic stem cells that arise during development. Nat Cell Biol. 2017 Jan; 19(1):17-27. Henninger J, Santoso B, Hans S, Durand E, Moore J, Mosimann C, Brand M, Traver D, Zon L. PMID: 27870830; PMCID: PMC5535785.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    38. CRISPR Guide RNA Validation In Vitro. Zebrafish. 2017 Aug; 14(4):383-386. Grainger S, Lonquich B, Oon CH, Nguyen N, Willert K, Traver D. PMID: 27829120; PMCID: PMC5549792.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    39. Ndrg1b and fam49ab modulate the PTEN pathway to control T-cell lymphopoiesis in the zebrafish. Blood. 2016 12 29; 128(26):3052-3060. Li RA, Traver D, Matthes T, Bertrand JY. PMID: 27827822.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    40. Wnt9a Is Required for the Aortic Amplification of Nascent Hematopoietic Stem Cells. Cell Rep. 2016 11 01; 17(6):1595-1606. Grainger S, Richter J, Palazón RE, Pouget C, Lonquich B, Wirth S, Grassme KS, Herzog W, Swift MR, Weinstein BM, Traver D, Willert K. PMID: 27806298; PMCID: PMC6309681.
      View in: PubMed   Mentions: 38     Fields:    Translation:AnimalsCells
    41. De Novo Mutations in SON Disrupt RNA Splicing of Genes Essential for Brain Development and Metabolism, Causing an Intellectual-Disability Syndrome. Am J Hum Genet. 2016 09 01; 99(3):711-719. Kim JH, Shinde DN, Reijnders MRF, Hauser NS, Belmonte RL, Wilson GR, Bosch DGM, Bubulya PA, Shashi V, Petrovski S, Stone JK, Park EY, Veltman JA, Sinnema M, Stumpel CTRM, Draaisma JM, Nicolai J, University of Washington Center for Mendelian Genomics, Yntema HG, Lindstrom K, de Vries BBA, Jewett T, Santoro SL, Vogt J, Deciphering Developmental Disorders Study, Bachman KK, Seeley AH, Krokosky A, Turner C, Rohena L, Hempel M, Kortüm F, Lessel D, Neu A, Strom TM, Wieczorek D, Bramswig N, Laccone FA, Behunova J, Rehder H, Gordon CT, Rio M, Romana S, Tang S, El-Khechen D, Cho MT, McWalter K, Douglas G, Baskin B, Begtrup A, Funari T, Schoch K, Stegmann APA, Stevens SJC, Zhang DE, Traver D, Yao X, MacArthur DG, Brunner HG, Mancini GM, Myers RM, Owen LB, Lim ST, Stachura DL, Vissers LELM, Ahn EYE. PMID: 27545680; PMCID: PMC5011044.
      View in: PubMed   Mentions: 57     Fields:    Translation:HumansAnimalsCells
    42. The NF-κB family: Key players during embryonic development and HSC emergence. Exp Hematol. 2016 07; 44(7):519-27. Espín-Palazón R, Traver D. PMID: 27132652.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansAnimalsCells
    43. Ex vivo tools for the clonal analysis of zebrafish hematopoiesis. Nat Protoc. 2016 May; 11(5):1007-20. Svoboda O, Stachura DL, Machonova O, Zon LI, Traver D, Bartunek P. PMID: 27123951; PMCID: PMC5560128.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    44. Conserved IL-2Rγc Signaling Mediates Lymphopoiesis in Zebrafish. J Immunol. 2016 Jan 01; 196(1):135-43. Sertori R, Liongue C, Basheer F, Lewis KL, Rasighaemi P, de Coninck D, Traver D, Ward AC. PMID: 26590317.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    45. Complex regulation of HSC emergence by the Notch signaling pathway. Dev Biol. 2016 Jan 01; 409(1):129-138. Butko E, Pouget C, Traver D. PMID: 26586199; PMCID: PMC4708088.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansAnimalsCells
    46. Zebrafish embryonic stromal trunk (ZEST) cells support hematopoietic stem and progenitor cell (HSPC) proliferation, survival, and differentiation. Exp Hematol. 2015 Dec; 43(12):1047-61. Campbell C, Su T, Lau RP, Shah A, Laurie PC, Avalos B, Aggio J, Harris E, Traver D, Stachura DL. PMID: 26391449; PMCID: PMC4666736.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    47. Bacterial induction of Snail1 contributes to blood-brain barrier disruption. J Clin Invest. 2015 Jun; 125(6):2473-83. Kim BJ, Hancock BM, Bermudez A, Del Cid N, Reyes E, van Sorge NM, Lauth X, Smurthwaite CA, Hilton BJ, Stotland A, Banerjee A, Buchanan J, Wolkowicz R, Traver D, Doran KS. PMID: 25961453; PMCID: PMC4497739.
      View in: PubMed   Mentions: 78     Fields:    Translation:HumansAnimalsCells
    48. Going with the flow: how shear stress signals the emergence of adult hematopoiesis. J Exp Med. 2015 May 04; 212(5):600. Traver D. PMID: 25941320; PMCID: PMC4419338.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    49. Gata2b is a restricted early regulator of hemogenic endothelium in the zebrafish embryo. Development. 2015 Mar 15; 142(6):1050-61. Butko E, Distel M, Pouget C, Weijts B, Kobayashi I, Ng K, Mosimann C, Poulain FE, McPherson A, Ni CW, Stachura DL, Del Cid N, Espín-Palazón R, Lawson ND, Dorsky R, Clements WK, Traver D. PMID: 25758220; PMCID: PMC4360177.
      View in: PubMed   Mentions: 86     Fields:    Translation:AnimalsCells
    50. Intimacy of the niche: perivascular remodeling cuddles incoming HSCs. Cell Stem Cell. 2015 Feb 05; 16(2):109-10. Sahai-Hernandez P, Traver D. PMID: 25658365; PMCID: PMC5918686.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    51. Streptococcus agalactiae infection in zebrafish larvae. Microb Pathog. 2015 Feb; 79:57-60. Kim BJ, Hancock BM, Del Cid N, Bermudez A, Traver D, Doran KS. PMID: 25617657; PMCID: PMC4340774.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    52. Cell signaling pathways involved in hematopoietic stem cell specification. Exp Cell Res. 2014 Dec 10; 329(2):227-33. Kim AD, Stachura DL, Traver D. PMID: 25447318; PMCID: PMC4293272.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    53. FGF signalling specifies haematopoietic stem cells through its regulation of somitic Notch signalling. Nat Commun. 2014 Nov 27; 5:5583. Lee Y, Manegold JE, Kim AD, Pouget C, Stachura DL, Clements WK, Traver D. PMID: 25428693; PMCID: PMC4271318.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    54. FGF signalling restricts haematopoietic stem cell specification via modulation of the BMP pathway. Nat Commun. 2014 Nov 27; 5:5588. Pouget C, Peterkin T, Simões FC, Lee Y, Traver D, Patient R. PMID: 25429520; PMCID: PMC4374634.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    55. Proinflammatory signaling regulates hematopoietic stem cell emergence. Cell. 2014 Nov 20; 159(5):1070-1085. Espín-Palazón R, Stachura DL, Campbell CA, García-Moreno D, Del Cid N, Kim AD, Candel S, Meseguer J, Mulero V, Traver D. PMID: 25416946; PMCID: PMC4243083.
      View in: PubMed   Mentions: 198     Fields:    Translation:AnimalsCells
    56. Discrete Notch signaling requirements in the specification of hematopoietic stem cells. EMBO J. 2014 Oct 16; 33(20):2363-73. Kim AD, Melick CH, Clements WK, Stachura DL, Distel M, Panáková D, MacRae C, Mork LA, Crump JG, Traver D. PMID: 25230933; PMCID: PMC4253525.
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    57. Loss of IP3R-dependent Ca2+ signalling in thymocytes leads to aberrant development and acute lymphoblastic leukemia. Nat Commun. 2014 Sep 12; 5:4814. Ouyang K, Leandro Gomez-Amaro R, Stachura DL, Tang H, Peng X, Fang X, Traver D, Evans SM, Chen J. PMID: 25215520; PMCID: PMC5537137.
      View in: PubMed   Mentions: 41     Fields:    Translation:AnimalsCells
    58. Hematopoietic ontogeny in the axolotl. Blood. 2014 Aug 21; 124(8):1204-6. Stachura DL, Traver D. PMID: 25147373; PMCID: PMC4141503.
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    59. Jam1a-Jam2a interactions regulate haematopoietic stem cell fate through Notch signalling. Nature. 2014 Aug 21; 512(7514):319-23. Kobayashi I, Kobayashi-Sun J, Kim AD, Pouget C, Fujita N, Suda T, Traver D. PMID: 25119047; PMCID: PMC4237229.
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    60. A systems biology approach for defining the molecular framework of the hematopoietic stem cell niche. Cell Stem Cell. 2014 Sep 04; 15(3):376-391. Charbord P, Pouget C, Binder H, Dumont F, Stik G, Levy P, Allain F, Marchal C, Richter J, Uzan B, Pflumio F, Letourneur F, Wirth H, Dzierzak E, Traver D, Jaffredo T, Durand C. PMID: 25042701.
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    61. Dissection of vertebrate hematopoiesis using zebrafish thrombopoietin. Blood. 2014 Jul 10; 124(2):220-8. Svoboda O, Stachura DL, Machonová O, Pajer P, Brynda J, Zon LI, Traver D, Bartunek P. PMID: 24869937; PMCID: PMC4093681.
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    62. Perspectives on antigen presenting cells in zebrafish. Dev Comp Immunol. 2014 Sep; 46(1):63-73. Lewis KL, Del Cid N, Traver D. PMID: 24685511; PMCID: PMC4158852.
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    63. The zebrafish granulocyte colony-stimulating factors (Gcsfs): 2 paralogous cytokines and their roles in hematopoietic development and maintenance. Blood. 2013 Dec 05; 122(24):3918-28. Stachura DL, Svoboda O, Campbell CA, Espín-Palazón R, Lau RP, Zon LI, Bartunek P, Traver D. PMID: 24128862; PMCID: PMC3854111.
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    64. An evolutionarily conserved program of B-cell development and activation in zebrafish. Blood. 2013 Aug 22; 122(8):e1-11. Page DM, Wittamer V, Bertrand JY, Lewis KL, Pratt DN, Delgado N, Schale SE, McGue C, Jacobsen BH, Doty A, Pao Y, Yang H, Chi NC, Magor BG, Traver D. PMID: 23861249; PMCID: PMC3750348.
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    65. Signalling pathways that control vertebrate haematopoietic stem cell specification. Nat Rev Immunol. 2013 May; 13(5):336-48. Clements WK, Traver D. PMID: 23618830; PMCID: PMC4169178.
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    66. Development and characterization of anti-nitr9 antibodies. Adv Hematol. 2012; 2012:596925. Shah RN, Rodriguez-Nunez I, Eason DD, Haire RN, Bertrand JY, Wittamer V, Traver D, Nordone SK, Litman GW, Yoder JA. PMID: 23049557; PMCID: PMC3463160.
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    67. Fish pharming: zebrafish antileukemia screening. Blood. 2012 Jun 14; 119(24):5614-5. Clements WK, Traver D. PMID: 22700692.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    68. Small molecule-mediated activation of the integrin CD11b/CD18 reduces inflammatory disease. Sci Signal. 2011 Sep 06; 4(189):ra57. Maiguel D, Faridi MH, Wei C, Kuwano Y, Balla KM, Hernandez D, Barth CJ, Lugo G, Donnelly M, Nayer A, Moita LF, Schürer S, Traver D, Ruiz P, Vazquez-Padron RI, Ley K, Reiser J, Gupta V. PMID: 21900205; PMCID: PMC4507414.
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    69. A somitic Wnt16/Notch pathway specifies haematopoietic stem cells. Nature. 2011 Jun 08; 474(7350):220-4. Clements WK, Kim AD, Ong KG, Moore JC, Lawson ND, Traver D. PMID: 21654806; PMCID: PMC3304471.
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    70. Clonal analysis of hematopoietic progenitor cells in the zebrafish. Blood. 2011 Aug 04; 118(5):1274-82. Stachura DL, Svoboda O, Lau RP, Balla KM, Zon LI, Bartunek P, Traver D. PMID: 21415264; PMCID: PMC3152495.
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    71. Characterization of the mononuclear phagocyte system in zebrafish. Blood. 2011 Jun 30; 117(26):7126-35. Wittamer V, Bertrand JY, Gutschow PW, Traver D. PMID: 21406720.
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    72. Cellular dissection of zebrafish hematopoiesis. Methods Cell Biol. 2011; 101:75-110. Stachura DL, Traver D. PMID: 21550440.
      View in: PubMed   Mentions: 46     Fields:    Translation:Animals
    73. High-throughput chemical screen identifies a novel potent modulator of cellular circadian rhythms and reveals CKIα as a clock regulatory kinase. PLoS Biol. 2010 Dec 14; 8(12):e1000559. Hirota T, Lee JW, Lewis WG, Zhang EE, Breton G, Liu X, Garcia M, Peters EC, Etchegaray JP, Traver D, Schultz PG, Kay SA. PMID: 21179498; PMCID: PMC3001897.
      View in: PubMed   Mentions: 137     Fields:    Translation:HumansAnimalsCells
    74. T-lymphoblastic lymphoma cells express high levels of BCL2, S1P1, and ICAM1, leading to a blockade of tumor cell intravasation. Cancer Cell. 2010 Oct 19; 18(4):353-66. Feng H, Stachura DL, White RM, Gutierrez A, Zhang L, Sanda T, Jette CA, Testa JR, Neuberg DS, Langenau DM, Kutok JL, Zon LI, Traver D, Fleming MD, Kanki JP, Look AT. PMID: 20951945; PMCID: PMC3003429.
      View in: PubMed   Mentions: 79     Fields:    Translation:HumansAnimalsCells
    75. Identification of dendritic antigen-presenting cells in the zebrafish. Proc Natl Acad Sci U S A. 2010 Sep 07; 107(36):15850-5. Lugo-Villarino G, Balla KM, Stachura DL, Bañuelos K, Werneck MB, Traver D. PMID: 20733076; PMCID: PMC2936643.
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    76. Eosinophils in the zebrafish: prospective isolation, characterization, and eosinophilia induction by helminth determinants. Blood. 2010 Nov 11; 116(19):3944-54. Balla KM, Lugo-Villarino G, Spitsbergen JM, Stachura DL, Hu Y, Bañuelos K, Romo-Fewell O, Aroian RV, Traver D. PMID: 20713961; PMCID: PMC2981543.
      View in: PubMed   Mentions: 77     Fields:    Translation:AnimalsCells
    77. Haematopoietic stem cells derive directly from aortic endothelium during development. Nature. 2010 Mar 04; 464(7285):108-11. Bertrand JY, Chi NC, Santoso B, Teng S, Stainier DY, Traver D. PMID: 20154733; PMCID: PMC2858358.
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    78. Notch signaling distinguishes 2 waves of definitive hematopoiesis in the zebrafish embryo. Blood. 2010 Apr 08; 115(14):2777-83. Bertrand JY, Cisson JL, Stachura DL, Traver D. PMID: 20107232; PMCID: PMC2854425.
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    79. Developmental and tissue-specific expression of NITRs. Immunogenetics. 2010 Feb; 62(2):117-22. Yoder JA, Turner PM, Wright PD, Wittamer V, Bertrand JY, Traver D, Litman GW. PMID: 20012603; PMCID: PMC2814043.
      View in: PubMed   Mentions: 20     Fields:    Translation:Animals
    80. The role and regulation of friend of GATA-1 (FOG-1) during blood development in the zebrafish. Blood. 2009 Nov 19; 114(21):4654-63. Amigo JD, Ackermann GE, Cope JJ, Yu M, Cooney JD, Ma D, Langer NB, Shafizadeh E, Shaw GC, Horsely W, Trede NS, Davidson AJ, Barut BA, Zhou Y, Wojiski SA, Traver D, Moran TB, Kourkoulis G, Hsu K, Kanki JP, Shah DI, Lin HF, Handin RI, Cantor AB, Paw BH. PMID: 19729519; PMCID: PMC2780302.
      View in: PubMed   Mentions: 31     Fields:    Translation:Animals
    81. CD47 is upregulated on circulating hematopoietic stem cells and leukemia cells to avoid phagocytosis. Cell. 2009 Jul 23; 138(2):271-85. Jaiswal S, Jamieson CH, Pang WW, Park CY, Chao MP, Majeti R, Traver D, van Rooijen N, Weissman IL. PMID: 19632178; PMCID: PMC2775564.
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    82. Hematopoietic cell development in the zebrafish embryo. Curr Opin Hematol. 2009 Jul; 16(4):243-8. Bertrand JY, Traver D. PMID: 19491671.
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    83. Zebrafish wnt3 is expressed in developing neural tissue. Dev Dyn. 2009 Jul; 238(7):1788-95. Clements WK, Ong KG, Traver D. PMID: 19452545; PMCID: PMC3086138.
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    84. Zebrafish kidney stromal cell lines support multilineage hematopoiesis. Blood. 2009 Jul 09; 114(2):279-89. Stachura DL, Reyes JR, Bartunek P, Paw BH, Zon LI, Traver D. PMID: 19433857; PMCID: PMC2714204.
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    85. Mutations in the cilia gene ARL13B lead to the classical form of Joubert syndrome. Am J Hum Genet. 2008 Aug; 83(2):170-9. Cantagrel V, Silhavy JL, Bielas SL, Swistun D, Marsh SE, Bertrand JY, Audollent S, Attié-Bitach T, Holden KR, Dobyns WB, Traver D, Al-Gazali L, Ali BR, Lindner TH, Caspary T, Otto EA, Hildebrandt F, Glass IA, Logan CV, Johnson CA, Bennett C, Brancati F, International Joubert Syndrome Related Disorders Study Group, Valente EM, Woods CG, Gleeson JG. PMID: 18674751; PMCID: PMC2495072.
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    86. CD41+ cmyb+ precursors colonize the zebrafish pronephros by a novel migration route to initiate adult hematopoiesis. Development. 2008 May; 135(10):1853-62. Bertrand JY, Kim AD, Teng S, Traver D. PMID: 18417622; PMCID: PMC2762343.
      View in: PubMed   Mentions: 119     Fields:    Translation:AnimalsCells
    87. Definitive hematopoiesis initiates through a committed erythromyeloid progenitor in the zebrafish embryo. Development. 2007 Dec; 134(23):4147-56. Bertrand JY, Kim AD, Violette EP, Stachura DL, Cisson JL, Traver D. PMID: 17959717; PMCID: PMC2735398.
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    88. The zebrafish activating immune receptor Nitr9 signals via Dap12. Immunogenetics. 2007 Oct; 59(10):813-21. Wei S, Zhou JM, Chen X, Shah RN, Liu J, Orcutt TM, Traver D, Djeu JY, Litman GW, Yoder JA. PMID: 17891481; PMCID: PMC3709248.
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    89. The zebrafish vitronectin receptor: characterization of integrin alphaV and beta3 expression patterns in early vertebrate development. Dev Dyn. 2007 Aug; 236(8):2268-76. Ablooglu AJ, Kang J, Handin RI, Traver D, Shattil SJ. PMID: 17626277.
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    90. Structural characteristics of zebrafish orthologs of adaptor molecules that associate with transmembrane immune receptors. Gene. 2007 Oct 15; 401(1-2):154-64. Yoder JA, Orcutt TM, Traver D, Litman GW. PMID: 17719728; PMCID: PMC2049010.
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    91. Mitoferrin is essential for erythroid iron assimilation. Nature. 2006 Mar 02; 440(7080):96-100. Shaw GC, Cope JJ, Li L, Corson K, Hersey C, Ackermann GE, Gwynn B, Lambert AJ, Wingert RA, Traver D, Trede NS, Barut BA, Zhou Y, Minet E, Donovan A, Brownlie A, Balzan R, Weiss MJ, Peters LL, Kaplan J, Zon LI, Paw BH. PMID: 16511496.
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    92. Immune-related, lectin-like receptors are differentially expressed in the myeloid and lymphoid lineages of zebrafish. Immunogenetics. 2006 Feb; 58(1):31-40. Panagos PG, Dobrinski KP, Chen X, Grant AW, Traver D, Djeu JY, Wei S, Yoder JA. PMID: 16467987.
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    93. Hematopoietic stem cell fate is established by the Notch-Runx pathway. Genes Dev. 2005 Oct 01; 19(19):2331-42. Burns CE, Traver D, Mayhall E, Shepard JL, Zon LI. PMID: 16166372; PMCID: PMC1240042.
      View in: PubMed   Mentions: 217     Fields:    Translation:AnimalsCells
    94. Analysis of thrombocyte development in CD41-GFP transgenic zebrafish. Blood. 2005 Dec 01; 106(12):3803-10. Lin HF, Traver D, Zhu H, Dooley K, Paw BH, Zon LI, Handin RI. PMID: 16099879; PMCID: PMC1895094.
      View in: PubMed   Mentions: 193     Fields:    Translation:HumansAnimalsCells
    95. Regulation of the lmo2 promoter during hematopoietic and vascular development in zebrafish. Dev Biol. 2005 May 15; 281(2):256-69. Zhu H, Traver D, Davidson AJ, Dibiase A, Thisse C, Thisse B, Nimer S, Zon LI. PMID: 15893977.
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    96. Ferroportin1 is required for normal iron cycling in zebrafish. J Clin Invest. 2005 Jun; 115(6):1532-41. Fraenkel PG, Traver D, Donovan A, Zahrieh D, Zon LI. PMID: 15902304; PMCID: PMC1089797.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    97. The complex cartography of stem cell commitment. Cell. 2005 Apr 22; 121(2):160-2. Akashi K, Traver D, Zon LI. PMID: 15851023.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    98. BRAF mutations are sufficient to promote nevi formation and cooperate with p53 in the genesis of melanoma. Curr Biol. 2005 Feb 08; 15(3):249-54. Patton EE, Widlund HR, Kutok JL, Kopani KR, Amatruda JF, Murphey RD, Berghmans S, Mayhall EA, Traver D, Fletcher CD, Aster JC, Granter SR, Look AT, Lee C, Fisher DE, Zon LI. PMID: 15694309.
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    99. The zebrafish moonshine gene encodes transcriptional intermediary factor 1gamma, an essential regulator of hematopoiesis. PLoS Biol. 2004 Aug; 2(8):E237. Ransom DG, Bahary N, Niss K, Traver D, Burns C, Trede NS, Paffett-Lugassy N, Saganic WJ, Lim CA, Hersey C, Zhou Y, Barut BA, Lin S, Kingsley PD, Palis J, Orkin SH, Zon LI. PMID: 15314655; PMCID: PMC509301.
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    100. Plasmacytoid dendritic cells activate lymphoid-specific genetic programs irrespective of their cellular origin. Immunity. 2004 Jul; 21(1):43-53. Shigematsu H, Reizis B, Iwasaki H, Mizuno S, Hu D, Traver D, Leder P, Sakaguchi N, Akashi K. PMID: 15345219.
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    101. Effects of lethal irradiation in zebrafish and rescue by hematopoietic cell transplantation. Blood. 2004 Sep 01; 104(5):1298-305. Traver D, Winzeler A, Stern HM, Mayhall EA, Langenau DM, Kutok JL, Look AT, Zon LI. PMID: 15142873.
      View in: PubMed   Mentions: 74     Fields:    Translation:Animals
    102. In vivo tracking of T cell development, ablation, and engraftment in transgenic zebrafish. Proc Natl Acad Sci U S A. 2004 May 11; 101(19):7369-74. Langenau DM, Ferrando AA, Traver D, Kutok JL, Hezel JP, Kanki JP, Zon LI, Look AT, Trede NS. PMID: 15123839; PMCID: PMC409925.
      View in: PubMed   Mentions: 189     Fields:    Translation:AnimalsCells
    103. The use of zebrafish to understand immunity. Immunity. 2004 Apr; 20(4):367-79. Trede NS, Langenau DM, Traver D, Look AT, Zon LI. PMID: 15084267.
      View in: PubMed   Mentions: 234     Fields:    Translation:Animals
    104. The pu.1 promoter drives myeloid gene expression in zebrafish. Blood. 2004 Sep 01; 104(5):1291-7. Hsu K, Traver D, Kutok JL, Hagen A, Liu TX, Paw BH, Rhodes J, Berman JN, Zon LI, Kanki JP, Look AT. PMID: 14996705.
      View in: PubMed   Mentions: 64     Fields:    Translation:AnimalsCells
    105. Lineage commitment and developmental plasticity in early lymphoid progenitor subsets. Adv Immunol. 2004; 83:1-54. Traver D, Akashi K. PMID: 15135627.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    106. Cellular dissection of zebrafish hematopoiesis. Methods Cell Biol. 2004; 76:127-49. Traver D. PMID: 15602875.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    107. Transplantation and in vivo imaging of multilineage engraftment in zebrafish bloodless mutants. Nat Immunol. 2003 Dec; 4(12):1238-46. Traver D, Paw BH, Poss KD, Penberthy WT, Lin S, Zon LI. PMID: 14608381.
      View in: PubMed   Mentions: 424     Fields:    Translation:AnimalsCells
    108. Expression of BCR/ABL and BCL-2 in myeloid progenitors leads to myeloid leukemias. Proc Natl Acad Sci U S A. 2003 Aug 19; 100(17):10002-7. Jaiswal S, Traver D, Miyamoto T, Akashi K, Lagasse E, Weissman IL. PMID: 12890867; PMCID: PMC187741.
      View in: PubMed   Mentions: 53     Fields:    Translation:HumansAnimalsCells
    109. Myc-induced T cell leukemia in transgenic zebrafish. Science. 2003 Feb 07; 299(5608):887-90. Langenau DM, Traver D, Ferrando AA, Kutok JL, Aster JC, Kanki JP, Lin S, Prochownik E, Trede NS, Zon LI, Look AT. PMID: 12574629.
      View in: PubMed   Mentions: 231     Fields:    Translation:AnimalsCells
    110. The zebrafish as a model organism to study development of the immune system. Adv Immunol. 2003; 81:253-330. Traver D, Herbomel P, Patton EE, Murphey RD, Yoder JA, Litman GW, Catic A, Amemiya CT, Zon LI, Trede NS. PMID: 14711058.
      View in: PubMed   Mentions: 115     Fields:    Translation:Animals
    111. Intrinsic requirement for zinc finger transcription factor Gfi-1 in neutrophil differentiation. Immunity. 2003 Jan; 18(1):109-20. Hock H, Hamblen MJ, Rooke HM, Traver D, Bronson RT, Cameron S, Orkin SH. PMID: 12530980.
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    112. Expression of CD41 marks the initiation of definitive hematopoiesis in the mouse embryo. Blood. 2003 Jan 15; 101(2):508-16. Mikkola HK, Fujiwara Y, Schlaeger TM, Traver D, Orkin SH. PMID: 12393529.
      View in: PubMed   Mentions: 144     Fields:    Translation:AnimalsCells
    113. Myeloid progenitors protect against invasive aspergillosis and Pseudomonas aeruginosa infection following hematopoietic stem cell transplantation. Blood. 2002 Dec 15; 100(13):4660-7. BitMansour A, Burns SM, Traver D, Akashi K, Contag CH, Weissman IL, Brown JM. PMID: 12393415.
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    114. Walking the walk: migration and other common themes in blood and vascular development. Cell. 2002 Mar 22; 108(6):731-4. Traver D, Zon LI. PMID: 11955426.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
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