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Multimodal Investigation of Angiogenesis and Its Prevention by Small Compounds in a Zebrafish Cancer Model. Adv Sci (Weinh). 2025 Sep; 12(33):e15176.
Andreana M, Sentosa R, Sturtzel C, Pfister M, Werkmeister R, Schmitt A, Traver D, Leitgeb R, Drexler W, Distel M, Unterhuber A. PMID: 40557748; PMCID: PMC12412526.
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PubMed Mentions:
1 Fields:
Translation:
Animals
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T-Lymphoblastic Lymphoma Cells Express High Levels of BCL2, S1P1, and ICAM1, Leading to a Blockade of Tumor Cell Intravasation. Cancer Cell. 2024 Jun 10; 42(6):1130-1131.
Feng H, Stachura DL, White RM, Gutierrez A, Zhang L, Sanda T, Jette CA, Testa JR, Neuberg DS, Langenau DM, Kutok JL, Zon LI, Traver D, Fleming MD, Kanki JP, Look AT. PMID: 38861925; PMCID: PMC11253892.
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PubMed Mentions:
1 Fields:
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A multistep computational approach reveals a neuro-mesenchymal cell population in the embryonic hematopoietic stem cell niche. Development. 2024 Apr 01; 151(7).
Miladinovic O, Canto PY, Pouget C, Piau O, Radic N, Freschu P, Megherbi A, Brujas Prats C, Jacques S, Hirsinger E, Geeverding A, Dufour S, Petit L, Souyri M, North T, Isambert H, Traver D, Jaffredo T, Charbord P, Durand C. PMID: 38451068; PMCID: PMC11057820.
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PubMed Mentions:
6 Fields:
Translation:
AnimalsCells
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Comparative transcriptomics coupled to developmental grading via transgenic zebrafish reporter strains identifies conserved features in neutrophil maturation. Nat Commun. 2024 Feb 27; 15(1):1792.
Kirchberger S, Shoeb MR, Lazic D, Wenninger-Weinzierl A, Fischer K, Shaw LE, Nogueira F, Rifatbegovic F, Bozsaky E, Ladenstein R, Bodenmiller B, Lion T, Traver D, Farlik M, Schöfer C, Taschner-Mandl S, Halbritter F, Distel M. PMID: 38413586; PMCID: PMC10899643.
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PubMed Mentions:
8 Fields:
Translation:
HumansAnimalsCells
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Human pallial MGE-type GABAergic interneuron cell therapy for chronic focal epilepsy. Cell Stem Cell. 2023 10 05; 30(10):1331-1350.e11.
Bershteyn M, Bröer S, Parekh M, Maury Y, Havlicek S, Kriks S, Fuentealba L, Lee S, Zhou R, Subramanyam G, Sezan M, Sevilla ES, Blankenberger W, Spatazza J, Zhou L, Nethercott H, Traver D, Hampel P, Kim H, Watson M, Salter N, Nesterova A, Au W, Kriegstein A, Alvarez-Buylla A, Rubenstein J, Banik G, Bulfone A, Priest C, Nicholas CR. PMID: 37802038; PMCID: PMC10993865.
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PubMed Mentions:
22 Fields:
Translation:
HumansAnimalsCells
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Dermomyotome-derived endothelial cells migrate to the dorsal aorta to support hematopoietic stem cell emergence. Elife. 2023 09 11; 12.
Sahai-Hernandez P, Pouget C, Eyal S, Svoboda O, Chacon J, Grimm L, Gjøen T, Traver D. PMID: 37695317; PMCID: PMC10495111.
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PubMed Mentions:
11 Fields:
Translation:
AnimalsCells
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Systemic Inflammation and Normocytic Anemia in DOCK11 Deficiency. N Engl J Med. 2023 08 10; 389(6):527-539.
Block J, Rashkova C, Castanon I, Zoghi S, Platon J, Ardy RC, Fujiwara M, Chaves B, Schoppmeyer R, van der Made CI, Jimenez Heredia R, Harms FL, Alavi S, Alsina L, Sanchez Moreno P, Ávila Polo R, Cabrera-Pérez R, Kostel Bal S, Pfajfer L, Ransmayr B, Mautner AK, Kondo R, Tinnacher A, Caldera M, Schuster M, Domínguez Conde C, Platzer R, Salzer E, Boyer T, Brunner HG, Nooitgedagt-Frons JE, Iglesias E, Deyà-Martinez A, Camacho-Lovillo M, Menche J, Bock C, Huppa JB, Pickl WF, Distel M, Yoder JA, Traver D, Engelhardt KR, Linden T, Kager L, Hannich JT, Hoischen A, Hambleton S, Illsinger S, Da Costa L, Kutsche K, Chavoshzadeh Z, van Buul JD, Antón J, Calzada-Hernández J, Neth O, Viaud J, Nishikimi A, Dupré L, Boztug K. PMID: 37342957.
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PubMed Mentions:
6 Fields:
Translation:
HumansAnimals
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Long noncoding RNA HIKER regulates erythropoiesis in Monge's disease via CSNK2B. J Clin Invest. 2023 06 01; 133(11).
Azad P, Zhou D, Tu HC, Villafuerte FC, Traver D, Rana TM, Haddad GG. PMID: 37022795; PMCID: PMC10231995.
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PubMed Mentions:
6 Fields:
Translation:
HumansAnimals
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The sinusoidal hematopoietic niche is formed by Jam1a via Notch signaling in the zebrafish kidney. iScience. 2023 Apr 21; 26(4):106508.
Kondo M, Kimura K, Kobayashi-Sun J, Yamamori S, Taniguchi M, Traver D, Kobayashi I. PMID: 37123221; PMCID: PMC10139997.
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PubMed Mentions:
1
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Notch signaling enhances bone regeneration in the zebrafish mandible. Development. 2022 03 01; 149(5).
Kraus JM, Giovannone D, Rydzik R, Balsbaugh JL, Moss IL, Schwedler JL, Bertrand JY, Traver D, Hankenson KD, Crump JG, Youngstrom DW. PMID: 35178545; PMCID: PMC8959151.
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PubMed Mentions:
16 Fields:
Translation:
Animals
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Endothelial struts enable the generation of large lumenized blood vessels de novo. Nat Cell Biol. 2021 04; 23(4):322-329.
Weijts B, Shaked I, Ginsberg M, Kleinfeld D, Robin C, Traver D. PMID: 33837285; PMCID: PMC8500358.
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PubMed Mentions:
3 Fields:
Translation:
HumansCells
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A zebrafish model of granulin deficiency reveals essential roles in myeloid cell differentiation. Blood Adv. 2021 02 09; 5(3):796-811.
Campbell CA, Fursova O, Cheng X, Snella E, McCune A, Li L, Solchenberger B, Schmid B, Sahoo D, Morton M, Traver D, Espín-Palazón R. PMID: 33560393; PMCID: PMC7876888.
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PubMed Mentions:
12 Fields:
Translation:
HumansAnimals
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Zebrafish Kit ligands cooperate with erythropoietin to promote erythroid cell expansion. Blood Adv. 2020 12 08; 4(23):5915-5924.
Oltova J, Svoboda O, Machonova O, Svatonova P, Traver D, Kolar M, Bartunek P. PMID: 33259600; PMCID: PMC7724902.
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PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
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Haematopoietic stem cell-dependent Notch transcription is mediated by p53 through the Histone chaperone Supt16h. Nat Cell Biol. 2020 12; 22(12):1411-1422.
Espanola SG, Song H, Ryu E, Saxena A, Kim ES, Manegold JE, Nasamran CA, Sahoo D, Oh CK, Bickers C, Shin U, Grainger S, Park YH, Pandolfo L, Kang MS, Kang S, Myung K, Cooper KL, Yelon D, Traver D, Lee Y. PMID: 33230303; PMCID: PMC8092813.
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PubMed Mentions:
8 Fields:
Translation:
AnimalsCells
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Impact of COVID-19 on early career scientists: an optimistic guide for the future. BMC Biol. 2020 07 30; 18(1):95.
Termini CM, Traver D. PMID: 32731867; PMCID: PMC7391227.
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PubMed Mentions:
25 Fields:
Translation:
HumansPHPublic Health
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Evaluation of the Cunningham Panel™ in pediatric autoimmune neuropsychiatric disorder associated with streptococcal infection (PANDAS) and pediatric acute-onset neuropsychiatric syndrome (PANS): Changes in antineuronal antibody titers parallel changes in patient symptoms. J Neuroimmunol. 2020 02 15; 339:577138.
Shimasaki C, Frye RE, Trifiletti R, Cooperstock M, Kaplan G, Melamed I, Greenberg R, Katz A, Fier E, Kem D, Traver D, Dempsey T, Latimer ME, Cross A, Dunn JP, Bentley R, Alvarez K, Reim S, Appleman J. PMID: 31884258.
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PubMed Mentions:
23 Fields:
Translation:
Humans
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Enrichment of hematopoietic stem/progenitor cells in the zebrafish kidney. Sci Rep. 2019 10 02; 9(1):14205.
Kobayashi I, Kondo M, Yamamori S, Kobayashi-Sun J, Taniguchi M, Kanemaru K, Katakura F, Traver D. PMID: 31578390; PMCID: PMC6775131.
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PubMed Mentions:
23 Fields:
Translation:
AnimalsCells
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Direct Visualization of Live Zebrafish Glycans via Single-Step Metabolic Labeling with Fluorophore-Tagged Nucleotide Sugars. Angew Chem Int Ed Engl. 2019 10 01; 58(40):14327-14333.
Hong S, Sahai-Hernandez P, Chapla DG, Moremen KW, Traver D, Wu P. PMID: 31295389; PMCID: PMC6820142.
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PubMed Mentions:
6 Fields:
Translation:
AnimalsCells
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EGFR is required for Wnt9a-Fzd9b signalling specificity in haematopoietic stem cells. Nat Cell Biol. 2019 06; 21(6):721-730.
Grainger S, Nguyen N, Richter J, Setayesh J, Lonquich B, Oon CH, Wozniak JM, Barahona R, Kamei CN, Houston J, Carrillo-Terrazas M, Drummond IA, Gonzalez D, Willert K, Traver D. PMID: 31110287; PMCID: PMC6559346.
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PubMed Mentions:
37 Fields:
Translation:
HumansAnimalsCells
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Embryonic Immune Cells Remodel the Heart. Dev Cell. 2019 03 11; 48(5):595-596.
Grainger S, Traver D. PMID: 30861372.
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PubMed Mentions:
1 Fields:
Translation:
Cells
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AIBP-mediated cholesterol efflux instructs hematopoietic stem and progenitor cell fate. Science. 2019 03 08; 363(6431):1085-1088.
Gu Q, Yang X, Lv J, Zhang J, Xia B, Kim JD, Wang R, Xiong F, Meng S, Clements TP, Tandon B, Wagner DS, Diaz MF, Wenzel PL, Miller YI, Traver D, Cooke JP, Li W, Zon LI, Chen K, Bai Y, Fang L. PMID: 30705153; PMCID: PMC6469354.
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PubMed Mentions:
76 Fields:
Translation:
AnimalsCells
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Blood flow-induced Notch activation and endothelial migration enable vascular remodeling in zebrafish embryos. Nat Commun. 2018 12 14; 9(1):5314.
Weijts B, Gutierrez E, Saikin SK, Ablooglu AJ, Traver D, Groisman A, Tkachenko E. PMID: 30552331; PMCID: PMC6294260.
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PubMed Mentions:
43 Fields:
Translation:
AnimalsCells
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Zebrafish snai2 mutants fail to phenocopy morphant phenotypes. PLoS One. 2018; 13(9):e0202747.
Bickers C, Española SD, Grainger S, Pouget C, Traver D. PMID: 30208064; PMCID: PMC6135377.
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PubMed Mentions:
3 Fields:
Translation:
AnimalsCells
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Embryonic Microglia Derive from Primitive Macrophages and Are Replaced by cmyb-Dependent Definitive Microglia in Zebrafish. Cell Rep. 2018 07 03; 24(1):130-141.
Ferrero G, Mahony CB, Dupuis E, Yvernogeau L, Di Ruggiero E, Miserocchi M, Caron M, Robin C, Traver D, Bertrand JY, Wittamer V. PMID: 29972775.
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PubMed Mentions:
55 Fields:
Translation:
AnimalsCells
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Lipoprotein lipase regulates hematopoietic stem progenitor cell maintenance through DHA supply. Nat Commun. 2018 04 03; 9(1):1310.
Liu C, Han T, Stachura DL, Wang H, Vaisman BL, Kim J, Klemke RL, Remaley AT, Rana TM, Traver D, Miller YI. PMID: 29615667; PMCID: PMC5882990.
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PubMed Mentions:
22 Fields:
Translation:
HumansAnimalsCells
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WNT9A Is a Conserved Regulator of Hematopoietic Stem and Progenitor Cell Development. Genes (Basel). 2018 Jan 29; 9(2).
Richter J, Stanley EG, Ng ES, Elefanty AG, Traver D, Willert K. PMID: 29382179; PMCID: PMC5852562.
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PubMed Mentions:
12 Fields:
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Wnt Signaling in Hematological Malignancies. Prog Mol Biol Transl Sci. 2018 01; 153:321-341.
Grainger S, Traver D, Willert K. PMID: 29389522; PMCID: PMC5972548.
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PubMed Mentions:
29 Fields:
Translation:
HumansAnimalsCells
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Mecp2 regulates tnfa during zebrafish embryonic development and acute inflammation. Dis Model Mech. 2017 12 19; 10(12):1439-1451.
van der Vaart M, Svoboda O, Weijts BG, Espín-Palazón R, Sapp V, Pietri T, Bagnat M, Muotri AR, Traver D. PMID: 28993314; PMCID: PMC5769600.
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PubMed Mentions:
22 Fields:
Translation:
AnimalsCells
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Proinflammatory Signals as Fuel for the Fire of Hematopoietic Stem Cell Emergence. Trends Cell Biol. 2018 01; 28(1):58-66.
Espin-Palazon R, Weijts B, Mulero V, Traver D. PMID: 28882414.
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PubMed Mentions:
35 Fields:
Translation:
HumansAnimalsCells
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The role of Wnt signaling in hematopoietic stem cell development. Crit Rev Biochem Mol Biol. 2017 08; 52(4):414-424.
Richter J, Traver D, Willert K. PMID: 28508727; PMCID: PMC6104630.
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PubMed Mentions:
42 Fields:
Translation:
HumansAnimalsCells
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The Pu.1 target gene Zbtb11 regulates neutrophil development through its integrase-like HHCC zinc finger. Nat Commun. 2017 04 06; 8:14911.
Keightley MC, Carradice DP, Layton JE, Pase L, Bertrand JY, Wittig JG, Dakic A, Badrock AP, Cole NJ, Traver D, Nutt SL, McCoey J, Buckle AM, Heath JK, Lieschke GJ. PMID: 28382966; PMCID: PMC5384227.
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PubMed Mentions:
23 Fields:
Translation:
AnimalsCells
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Zebrafish Caudal Haematopoietic Embryonic Stromal Tissue (CHEST) Cells Support Haematopoiesis. Sci Rep. 2017 03 16; 7:44644.
Wolf A, Aggio J, Campbell C, Wright F, Marquez G, Traver D, Stachura DL. PMID: 28300168; PMCID: PMC5353684.
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PubMed Mentions:
16 Fields:
Translation:
AnimalsCells
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Corrigendum: Clonal fate mapping quantifies the number of haematopoietic stem cells that arise during development. Nat Cell Biol. 2017 01 31; 19(2):142.
Henninger J, Santoso B, Hans S, Durand E, Moore J, Mosimann C, Brand M, Traver D, Zon L. PMID: 28139650; PMCID: PMC5898623.
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PubMed Mentions:
42 Fields:
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A Four-Well Dish for High-Resolution Longitudinal Imaging of the Tail and Posterior Trunk of Larval Zebrafish. Zebrafish. 2017 10; 14(5):489-491.
Weijts B, Tkachenko E, Traver D, Groisman A. PMID: 28118101; PMCID: PMC5650709.
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PubMed Mentions:
4 Fields:
Translation:
Animals
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Biallelic mutations in the 3' exonuclease TOE1 cause pontocerebellar hypoplasia and uncover a role in snRNA processing. Nat Genet. 2017 Mar; 49(3):457-464.
Lardelli RM, Schaffer AE, Eggens VR, Zaki MS, Grainger S, Sathe S, Van Nostrand EL, Schlachetzki Z, Rosti B, Akizu N, Scott E, Silhavy JL, Heckman LD, Rosti RO, Dikoglu E, Gregor A, Guemez-Gamboa A, Musaev D, Mande R, Widjaja A, Shaw TL, Markmiller S, Marin-Valencia I, Davies JH, de Meirleir L, Kayserili H, Altunoglu U, Freckmann ML, Warwick L, Chitayat D, Blaser S, Çaglayan AO, Bilguvar K, Per H, Fagerberg C, Christesen HT, Kibaek M, Aldinger KA, Manchester D, Matsumoto N, Muramatsu K, Saitsu H, Shiina M, Ogata K, Foulds N, Dobyns WB, Chi NC, Traver D, Spaccini L, Bova SM, Gabriel SB, Gunel M, Valente EM, Nassogne MC, Bennett EJ, Yeo GW, Baas F, Lykke-Andersen J, Gleeson JG. PMID: 28092684; PMCID: PMC5325768.
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PubMed Mentions:
51 Fields:
Translation:
HumansAnimalsCells
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Comparative Analysis of Vertebrate Diurnal/Circadian Transcriptomes. PLoS One. 2017; 12(1):e0169923.
Boyle G, Richter K, Priest HD, Traver D, Mockler TC, Chang JT, Kay SA, Breton G. PMID: 28076377; PMCID: PMC5226840.
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PubMed Mentions:
9 Fields:
Translation:
AnimalsCells
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Clonal fate mapping quantifies the number of haematopoietic stem cells that arise during development. Nat Cell Biol. 2017 Jan; 19(1):17-27.
Henninger J, Santoso B, Hans S, Durand E, Moore J, Mosimann C, Brand M, Traver D, Zon L. PMID: 27870830; PMCID: PMC5535785.
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PubMed Mentions:
22 Fields:
Translation:
AnimalsCells
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CRISPR Guide RNA Validation In Vitro. Zebrafish. 2017 Aug; 14(4):383-386.
Grainger S, Lonquich B, Oon CH, Nguyen N, Willert K, Traver D. PMID: 27829120; PMCID: PMC5549792.
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PubMed Mentions:
10 Fields:
Translation:
Animals
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Ndrg1b and fam49ab modulate the PTEN pathway to control T-cell lymphopoiesis in the zebrafish. Blood. 2016 12 29; 128(26):3052-3060.
Li RA, Traver D, Matthes T, Bertrand JY. PMID: 27827822.
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PubMed Mentions:
4 Fields:
Translation:
AnimalsCells
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Wnt9a Is Required for the Aortic Amplification of Nascent Hematopoietic Stem Cells. Cell Rep. 2016 11 01; 17(6):1595-1606.
Grainger S, Richter J, Palazón RE, Pouget C, Lonquich B, Wirth S, Grassme KS, Herzog W, Swift MR, Weinstein BM, Traver D, Willert K. PMID: 27806298; PMCID: PMC6309681.
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PubMed Mentions:
38 Fields:
Translation:
AnimalsCells
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De Novo Mutations in SON Disrupt RNA Splicing of Genes Essential for Brain Development and Metabolism, Causing an Intellectual-Disability Syndrome. Am J Hum Genet. 2016 09 01; 99(3):711-719.
Kim JH, Shinde DN, Reijnders MRF, Hauser NS, Belmonte RL, Wilson GR, Bosch DGM, Bubulya PA, Shashi V, Petrovski S, Stone JK, Park EY, Veltman JA, Sinnema M, Stumpel CTRM, Draaisma JM, Nicolai J, University of Washington Center for Mendelian Genomics, Yntema HG, Lindstrom K, de Vries BBA, Jewett T, Santoro SL, Vogt J, Deciphering Developmental Disorders Study, Bachman KK, Seeley AH, Krokosky A, Turner C, Rohena L, Hempel M, Kortüm F, Lessel D, Neu A, Strom TM, Wieczorek D, Bramswig N, Laccone FA, Behunova J, Rehder H, Gordon CT, Rio M, Romana S, Tang S, El-Khechen D, Cho MT, McWalter K, Douglas G, Baskin B, Begtrup A, Funari T, Schoch K, Stegmann APA, Stevens SJC, Zhang DE, Traver D, Yao X, MacArthur DG, Brunner HG, Mancini GM, Myers RM, Owen LB, Lim ST, Stachura DL, Vissers LELM, Ahn EYE. PMID: 27545680; PMCID: PMC5011044.
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PubMed Mentions:
57 Fields:
Translation:
HumansAnimalsCells
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The NF-κB family: Key players during embryonic development and HSC emergence. Exp Hematol. 2016 07; 44(7):519-27.
Espín-Palazón R, Traver D. PMID: 27132652.
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PubMed Mentions:
50 Fields:
Translation:
HumansAnimalsCells
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Ex vivo tools for the clonal analysis of zebrafish hematopoiesis. Nat Protoc. 2016 May; 11(5):1007-20.
Svoboda O, Stachura DL, Machonova O, Zon LI, Traver D, Bartunek P. PMID: 27123951; PMCID: PMC5560128.
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PubMed Mentions:
15 Fields:
Translation:
AnimalsCells
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Conserved IL-2Rγc Signaling Mediates Lymphopoiesis in Zebrafish. J Immunol. 2016 Jan 01; 196(1):135-43.
Sertori R, Liongue C, Basheer F, Lewis KL, Rasighaemi P, de Coninck D, Traver D, Ward AC. PMID: 26590317.
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PubMed Mentions:
12 Fields:
Translation:
HumansAnimalsCells
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Complex regulation of HSC emergence by the Notch signaling pathway. Dev Biol. 2016 Jan 01; 409(1):129-138.
Butko E, Pouget C, Traver D. PMID: 26586199; PMCID: PMC4708088.
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PubMed Mentions:
42 Fields:
Translation:
HumansAnimalsCells
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Zebrafish embryonic stromal trunk (ZEST) cells support hematopoietic stem and progenitor cell (HSPC) proliferation, survival, and differentiation. Exp Hematol. 2015 Dec; 43(12):1047-61.
Campbell C, Su T, Lau RP, Shah A, Laurie PC, Avalos B, Aggio J, Harris E, Traver D, Stachura DL. PMID: 26391449; PMCID: PMC4666736.
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PubMed Mentions:
13 Fields:
Translation:
AnimalsCells
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Bacterial induction of Snail1 contributes to blood-brain barrier disruption. J Clin Invest. 2015 Jun; 125(6):2473-83.
Kim BJ, Hancock BM, Bermudez A, Del Cid N, Reyes E, van Sorge NM, Lauth X, Smurthwaite CA, Hilton BJ, Stotland A, Banerjee A, Buchanan J, Wolkowicz R, Traver D, Doran KS. PMID: 25961453; PMCID: PMC4497739.
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PubMed Mentions:
78 Fields:
Translation:
HumansAnimalsCells
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Going with the flow: how shear stress signals the emergence of adult hematopoiesis. J Exp Med. 2015 May 04; 212(5):600.
Traver D. PMID: 25941320; PMCID: PMC4419338.
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PubMed Mentions:
3 Fields:
Translation:
HumansAnimalsCells
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Gata2b is a restricted early regulator of hemogenic endothelium in the zebrafish embryo. Development. 2015 Mar 15; 142(6):1050-61.
Butko E, Distel M, Pouget C, Weijts B, Kobayashi I, Ng K, Mosimann C, Poulain FE, McPherson A, Ni CW, Stachura DL, Del Cid N, Espín-Palazón R, Lawson ND, Dorsky R, Clements WK, Traver D. PMID: 25758220; PMCID: PMC4360177.
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PubMed Mentions:
86 Fields:
Translation:
AnimalsCells
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Intimacy of the niche: perivascular remodeling cuddles incoming HSCs. Cell Stem Cell. 2015 Feb 05; 16(2):109-10.
Sahai-Hernandez P, Traver D. PMID: 25658365; PMCID: PMC5918686.
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PubMed Mentions: Fields:
Translation:
AnimalsCells
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Streptococcus agalactiae infection in zebrafish larvae. Microb Pathog. 2015 Feb; 79:57-60.
Kim BJ, Hancock BM, Del Cid N, Bermudez A, Traver D, Doran KS. PMID: 25617657; PMCID: PMC4340774.
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PubMed Mentions:
20 Fields:
Translation:
AnimalsCells
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Cell signaling pathways involved in hematopoietic stem cell specification. Exp Cell Res. 2014 Dec 10; 329(2):227-33.
Kim AD, Stachura DL, Traver D. PMID: 25447318; PMCID: PMC4293272.
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PubMed Mentions:
21 Fields:
Translation:
HumansAnimalsCells
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FGF signalling specifies haematopoietic stem cells through its regulation of somitic Notch signalling. Nat Commun. 2014 Nov 27; 5:5583.
Lee Y, Manegold JE, Kim AD, Pouget C, Stachura DL, Clements WK, Traver D. PMID: 25428693; PMCID: PMC4271318.
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PubMed Mentions:
27 Fields:
Translation:
AnimalsCells
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FGF signalling restricts haematopoietic stem cell specification via modulation of the BMP pathway. Nat Commun. 2014 Nov 27; 5:5588.
Pouget C, Peterkin T, Simões FC, Lee Y, Traver D, Patient R. PMID: 25429520; PMCID: PMC4374634.
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PubMed Mentions:
32 Fields:
Translation:
AnimalsCells
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Proinflammatory signaling regulates hematopoietic stem cell emergence. Cell. 2014 Nov 20; 159(5):1070-1085.
Espín-Palazón R, Stachura DL, Campbell CA, García-Moreno D, Del Cid N, Kim AD, Candel S, Meseguer J, Mulero V, Traver D. PMID: 25416946; PMCID: PMC4243083.
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PubMed Mentions:
198 Fields:
Translation:
AnimalsCells
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Discrete Notch signaling requirements in the specification of hematopoietic stem cells. EMBO J. 2014 Oct 16; 33(20):2363-73.
Kim AD, Melick CH, Clements WK, Stachura DL, Distel M, Panáková D, MacRae C, Mork LA, Crump JG, Traver D. PMID: 25230933; PMCID: PMC4253525.
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PubMed Mentions:
61 Fields:
Translation:
AnimalsCells
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Loss of IP3R-dependent Ca2+ signalling in thymocytes leads to aberrant development and acute lymphoblastic leukemia. Nat Commun. 2014 Sep 12; 5:4814.
Ouyang K, Leandro Gomez-Amaro R, Stachura DL, Tang H, Peng X, Fang X, Traver D, Evans SM, Chen J. PMID: 25215520; PMCID: PMC5537137.
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PubMed Mentions:
41 Fields:
Translation:
AnimalsCells
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Hematopoietic ontogeny in the axolotl. Blood. 2014 Aug 21; 124(8):1204-6.
Stachura DL, Traver D. PMID: 25147373; PMCID: PMC4141503.
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PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
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Jam1a-Jam2a interactions regulate haematopoietic stem cell fate through Notch signalling. Nature. 2014 Aug 21; 512(7514):319-23.
Kobayashi I, Kobayashi-Sun J, Kim AD, Pouget C, Fujita N, Suda T, Traver D. PMID: 25119047; PMCID: PMC4237229.
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PubMed Mentions:
95 Fields:
Translation:
AnimalsCells
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A systems biology approach for defining the molecular framework of the hematopoietic stem cell niche. Cell Stem Cell. 2014 Sep 04; 15(3):376-391.
Charbord P, Pouget C, Binder H, Dumont F, Stik G, Levy P, Allain F, Marchal C, Richter J, Uzan B, Pflumio F, Letourneur F, Wirth H, Dzierzak E, Traver D, Jaffredo T, Durand C. PMID: 25042701.
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PubMed Mentions:
43 Fields:
Translation:
HumansAnimalsCells
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Dissection of vertebrate hematopoiesis using zebrafish thrombopoietin. Blood. 2014 Jul 10; 124(2):220-8.
Svoboda O, Stachura DL, Machonová O, Pajer P, Brynda J, Zon LI, Traver D, Bartunek P. PMID: 24869937; PMCID: PMC4093681.
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PubMed Mentions:
22 Fields:
Translation:
AnimalsCells
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Perspectives on antigen presenting cells in zebrafish. Dev Comp Immunol. 2014 Sep; 46(1):63-73.
Lewis KL, Del Cid N, Traver D. PMID: 24685511; PMCID: PMC4158852.
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PubMed Mentions:
25 Fields:
Translation:
AnimalsCells
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The zebrafish granulocyte colony-stimulating factors (Gcsfs): 2 paralogous cytokines and their roles in hematopoietic development and maintenance. Blood. 2013 Dec 05; 122(24):3918-28.
Stachura DL, Svoboda O, Campbell CA, Espín-Palazón R, Lau RP, Zon LI, Bartunek P, Traver D. PMID: 24128862; PMCID: PMC3854111.
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PubMed Mentions:
57 Fields:
Translation:
AnimalsCells
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An evolutionarily conserved program of B-cell development and activation in zebrafish. Blood. 2013 Aug 22; 122(8):e1-11.
Page DM, Wittamer V, Bertrand JY, Lewis KL, Pratt DN, Delgado N, Schale SE, McGue C, Jacobsen BH, Doty A, Pao Y, Yang H, Chi NC, Magor BG, Traver D. PMID: 23861249; PMCID: PMC3750348.
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PubMed Mentions:
100 Fields:
Translation:
AnimalsCells
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Signalling pathways that control vertebrate haematopoietic stem cell specification. Nat Rev Immunol. 2013 May; 13(5):336-48.
Clements WK, Traver D. PMID: 23618830; PMCID: PMC4169178.
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PubMed Mentions:
89 Fields:
Translation:
AnimalsCells
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Development and characterization of anti-nitr9 antibodies. Adv Hematol. 2012; 2012:596925.
Shah RN, Rodriguez-Nunez I, Eason DD, Haire RN, Bertrand JY, Wittamer V, Traver D, Nordone SK, Litman GW, Yoder JA. PMID: 23049557; PMCID: PMC3463160.
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PubMed Mentions:
5
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Fish pharming: zebrafish antileukemia screening. Blood. 2012 Jun 14; 119(24):5614-5.
Clements WK, Traver D. PMID: 22700692.
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PubMed Mentions:
5 Fields:
Translation:
HumansAnimals
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Small molecule-mediated activation of the integrin CD11b/CD18 reduces inflammatory disease. Sci Signal. 2011 Sep 06; 4(189):ra57.
Maiguel D, Faridi MH, Wei C, Kuwano Y, Balla KM, Hernandez D, Barth CJ, Lugo G, Donnelly M, Nayer A, Moita LF, Schürer S, Traver D, Ruiz P, Vazquez-Padron RI, Ley K, Reiser J, Gupta V. PMID: 21900205; PMCID: PMC4507414.
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PubMed Mentions:
79 Fields:
Translation:
HumansAnimalsCells
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A somitic Wnt16/Notch pathway specifies haematopoietic stem cells. Nature. 2011 Jun 08; 474(7350):220-4.
Clements WK, Kim AD, Ong KG, Moore JC, Lawson ND, Traver D. PMID: 21654806; PMCID: PMC3304471.
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PubMed Mentions:
133 Fields:
Translation:
AnimalsCells
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Clonal analysis of hematopoietic progenitor cells in the zebrafish. Blood. 2011 Aug 04; 118(5):1274-82.
Stachura DL, Svoboda O, Lau RP, Balla KM, Zon LI, Bartunek P, Traver D. PMID: 21415264; PMCID: PMC3152495.
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PubMed Mentions:
32 Fields:
Translation:
AnimalsCells
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Characterization of the mononuclear phagocyte system in zebrafish. Blood. 2011 Jun 30; 117(26):7126-35.
Wittamer V, Bertrand JY, Gutschow PW, Traver D. PMID: 21406720.
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PubMed Mentions:
97 Fields:
Translation:
AnimalsCells
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Cellular dissection of zebrafish hematopoiesis. Methods Cell Biol. 2011; 101:75-110.
Stachura DL, Traver D. PMID: 21550440.
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PubMed Mentions:
46 Fields:
Translation:
Animals
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High-throughput chemical screen identifies a novel potent modulator of cellular circadian rhythms and reveals CKIα as a clock regulatory kinase. PLoS Biol. 2010 Dec 14; 8(12):e1000559.
Hirota T, Lee JW, Lewis WG, Zhang EE, Breton G, Liu X, Garcia M, Peters EC, Etchegaray JP, Traver D, Schultz PG, Kay SA. PMID: 21179498; PMCID: PMC3001897.
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PubMed Mentions:
137 Fields:
Translation:
HumansAnimalsCells
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T-lymphoblastic lymphoma cells express high levels of BCL2, S1P1, and ICAM1, leading to a blockade of tumor cell intravasation. Cancer Cell. 2010 Oct 19; 18(4):353-66.
Feng H, Stachura DL, White RM, Gutierrez A, Zhang L, Sanda T, Jette CA, Testa JR, Neuberg DS, Langenau DM, Kutok JL, Zon LI, Traver D, Fleming MD, Kanki JP, Look AT. PMID: 20951945; PMCID: PMC3003429.
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PubMed Mentions:
79 Fields:
Translation:
HumansAnimalsCells
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Identification of dendritic antigen-presenting cells in the zebrafish. Proc Natl Acad Sci U S A. 2010 Sep 07; 107(36):15850-5.
Lugo-Villarino G, Balla KM, Stachura DL, Bañuelos K, Werneck MB, Traver D. PMID: 20733076; PMCID: PMC2936643.
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PubMed Mentions:
110 Fields:
Translation:
AnimalsCells
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Eosinophils in the zebrafish: prospective isolation, characterization, and eosinophilia induction by helminth determinants. Blood. 2010 Nov 11; 116(19):3944-54.
Balla KM, Lugo-Villarino G, Spitsbergen JM, Stachura DL, Hu Y, Bañuelos K, Romo-Fewell O, Aroian RV, Traver D. PMID: 20713961; PMCID: PMC2981543.
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PubMed Mentions:
77 Fields:
Translation:
AnimalsCells
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Haematopoietic stem cells derive directly from aortic endothelium during development. Nature. 2010 Mar 04; 464(7285):108-11.
Bertrand JY, Chi NC, Santoso B, Teng S, Stainier DY, Traver D. PMID: 20154733; PMCID: PMC2858358.
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PubMed Mentions:
572 Fields:
Translation:
AnimalsCells
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Notch signaling distinguishes 2 waves of definitive hematopoiesis in the zebrafish embryo. Blood. 2010 Apr 08; 115(14):2777-83.
Bertrand JY, Cisson JL, Stachura DL, Traver D. PMID: 20107232; PMCID: PMC2854425.
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PubMed Mentions:
65 Fields:
Translation:
AnimalsCells
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Developmental and tissue-specific expression of NITRs. Immunogenetics. 2010 Feb; 62(2):117-22.
Yoder JA, Turner PM, Wright PD, Wittamer V, Bertrand JY, Traver D, Litman GW. PMID: 20012603; PMCID: PMC2814043.
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PubMed Mentions:
20 Fields:
Translation:
Animals
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The role and regulation of friend of GATA-1 (FOG-1) during blood development in the zebrafish. Blood. 2009 Nov 19; 114(21):4654-63.
Amigo JD, Ackermann GE, Cope JJ, Yu M, Cooney JD, Ma D, Langer NB, Shafizadeh E, Shaw GC, Horsely W, Trede NS, Davidson AJ, Barut BA, Zhou Y, Wojiski SA, Traver D, Moran TB, Kourkoulis G, Hsu K, Kanki JP, Shah DI, Lin HF, Handin RI, Cantor AB, Paw BH. PMID: 19729519; PMCID: PMC2780302.
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PubMed Mentions:
31 Fields:
Translation:
Animals
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CD47 is upregulated on circulating hematopoietic stem cells and leukemia cells to avoid phagocytosis. Cell. 2009 Jul 23; 138(2):271-85.
Jaiswal S, Jamieson CH, Pang WW, Park CY, Chao MP, Majeti R, Traver D, van Rooijen N, Weissman IL. PMID: 19632178; PMCID: PMC2775564.
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PubMed Mentions:
887 Fields:
Translation:
HumansAnimalsCells
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Hematopoietic cell development in the zebrafish embryo. Curr Opin Hematol. 2009 Jul; 16(4):243-8.
Bertrand JY, Traver D. PMID: 19491671.
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PubMed Mentions:
40 Fields:
Translation:
AnimalsCells
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Zebrafish wnt3 is expressed in developing neural tissue. Dev Dyn. 2009 Jul; 238(7):1788-95.
Clements WK, Ong KG, Traver D. PMID: 19452545; PMCID: PMC3086138.
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PubMed Mentions:
21 Fields:
Translation:
AnimalsCells
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Zebrafish kidney stromal cell lines support multilineage hematopoiesis. Blood. 2009 Jul 09; 114(2):279-89.
Stachura DL, Reyes JR, Bartunek P, Paw BH, Zon LI, Traver D. PMID: 19433857; PMCID: PMC2714204.
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PubMed Mentions:
52 Fields:
Translation:
AnimalsCells
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Mutations in the cilia gene ARL13B lead to the classical form of Joubert syndrome. Am J Hum Genet. 2008 Aug; 83(2):170-9.
Cantagrel V, Silhavy JL, Bielas SL, Swistun D, Marsh SE, Bertrand JY, Audollent S, Attié-Bitach T, Holden KR, Dobyns WB, Traver D, Al-Gazali L, Ali BR, Lindner TH, Caspary T, Otto EA, Hildebrandt F, Glass IA, Logan CV, Johnson CA, Bennett C, Brancati F, International Joubert Syndrome Related Disorders Study Group, Valente EM, Woods CG, Gleeson JG. PMID: 18674751; PMCID: PMC2495072.
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PubMed Mentions:
219 Fields:
Translation:
HumansAnimalsCells
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CD41+ cmyb+ precursors colonize the zebrafish pronephros by a novel migration route to initiate adult hematopoiesis. Development. 2008 May; 135(10):1853-62.
Bertrand JY, Kim AD, Teng S, Traver D. PMID: 18417622; PMCID: PMC2762343.
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PubMed Mentions:
119 Fields:
Translation:
AnimalsCells
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Definitive hematopoiesis initiates through a committed erythromyeloid progenitor in the zebrafish embryo. Development. 2007 Dec; 134(23):4147-56.
Bertrand JY, Kim AD, Violette EP, Stachura DL, Cisson JL, Traver D. PMID: 17959717; PMCID: PMC2735398.
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PubMed Mentions:
173 Fields:
Translation:
AnimalsCells
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The zebrafish activating immune receptor Nitr9 signals via Dap12. Immunogenetics. 2007 Oct; 59(10):813-21.
Wei S, Zhou JM, Chen X, Shah RN, Liu J, Orcutt TM, Traver D, Djeu JY, Litman GW, Yoder JA. PMID: 17891481; PMCID: PMC3709248.
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PubMed Mentions:
22 Fields:
Translation:
HumansAnimalsCells
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The zebrafish vitronectin receptor: characterization of integrin alphaV and beta3 expression patterns in early vertebrate development. Dev Dyn. 2007 Aug; 236(8):2268-76.
Ablooglu AJ, Kang J, Handin RI, Traver D, Shattil SJ. PMID: 17626277.
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PubMed Mentions:
13 Fields:
Translation:
Animals
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Structural characteristics of zebrafish orthologs of adaptor molecules that associate with transmembrane immune receptors. Gene. 2007 Oct 15; 401(1-2):154-64.
Yoder JA, Orcutt TM, Traver D, Litman GW. PMID: 17719728; PMCID: PMC2049010.
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PubMed Mentions:
22 Fields:
Translation:
AnimalsCells
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Mitoferrin is essential for erythroid iron assimilation. Nature. 2006 Mar 02; 440(7080):96-100.
Shaw GC, Cope JJ, Li L, Corson K, Hersey C, Ackermann GE, Gwynn B, Lambert AJ, Wingert RA, Traver D, Trede NS, Barut BA, Zhou Y, Minet E, Donovan A, Brownlie A, Balzan R, Weiss MJ, Peters LL, Kaplan J, Zon LI, Paw BH. PMID: 16511496.
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PubMed Mentions:
309 Fields:
Translation:
HumansAnimalsCells
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Immune-related, lectin-like receptors are differentially expressed in the myeloid and lymphoid lineages of zebrafish. Immunogenetics. 2006 Feb; 58(1):31-40.
Panagos PG, Dobrinski KP, Chen X, Grant AW, Traver D, Djeu JY, Wei S, Yoder JA. PMID: 16467987.
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PubMed Mentions:
14 Fields:
Translation:
AnimalsCells
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Hematopoietic stem cell fate is established by the Notch-Runx pathway. Genes Dev. 2005 Oct 01; 19(19):2331-42.
Burns CE, Traver D, Mayhall E, Shepard JL, Zon LI. PMID: 16166372; PMCID: PMC1240042.
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PubMed Mentions:
217 Fields:
Translation:
AnimalsCells
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Analysis of thrombocyte development in CD41-GFP transgenic zebrafish. Blood. 2005 Dec 01; 106(12):3803-10.
Lin HF, Traver D, Zhu H, Dooley K, Paw BH, Zon LI, Handin RI. PMID: 16099879; PMCID: PMC1895094.
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PubMed Mentions:
193 Fields:
Translation:
HumansAnimalsCells
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Regulation of the lmo2 promoter during hematopoietic and vascular development in zebrafish. Dev Biol. 2005 May 15; 281(2):256-69.
Zhu H, Traver D, Davidson AJ, Dibiase A, Thisse C, Thisse B, Nimer S, Zon LI. PMID: 15893977.
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PubMed Mentions:
51 Fields:
Translation:
AnimalsCells
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Ferroportin1 is required for normal iron cycling in zebrafish. J Clin Invest. 2005 Jun; 115(6):1532-41.
Fraenkel PG, Traver D, Donovan A, Zahrieh D, Zon LI. PMID: 15902304; PMCID: PMC1089797.
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PubMed Mentions:
31 Fields:
Translation:
HumansAnimalsCells
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The complex cartography of stem cell commitment. Cell. 2005 Apr 22; 121(2):160-2.
Akashi K, Traver D, Zon LI. PMID: 15851023.
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PubMed Mentions:
11 Fields:
Translation:
AnimalsCells
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BRAF mutations are sufficient to promote nevi formation and cooperate with p53 in the genesis of melanoma. Curr Biol. 2005 Feb 08; 15(3):249-54.
Patton EE, Widlund HR, Kutok JL, Kopani KR, Amatruda JF, Murphey RD, Berghmans S, Mayhall EA, Traver D, Fletcher CD, Aster JC, Granter SR, Look AT, Lee C, Fisher DE, Zon LI. PMID: 15694309.
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PubMed Mentions:
287 Fields:
Translation:
AnimalsCells
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The zebrafish moonshine gene encodes transcriptional intermediary factor 1gamma, an essential regulator of hematopoiesis. PLoS Biol. 2004 Aug; 2(8):E237.
Ransom DG, Bahary N, Niss K, Traver D, Burns C, Trede NS, Paffett-Lugassy N, Saganic WJ, Lim CA, Hersey C, Zhou Y, Barut BA, Lin S, Kingsley PD, Palis J, Orkin SH, Zon LI. PMID: 15314655; PMCID: PMC509301.
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PubMed Mentions:
61 Fields:
Translation:
AnimalsCells
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Plasmacytoid dendritic cells activate lymphoid-specific genetic programs irrespective of their cellular origin. Immunity. 2004 Jul; 21(1):43-53.
Shigematsu H, Reizis B, Iwasaki H, Mizuno S, Hu D, Traver D, Leder P, Sakaguchi N, Akashi K. PMID: 15345219.
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PubMed Mentions:
100 Fields:
Translation:
HumansAnimalsCells
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Effects of lethal irradiation in zebrafish and rescue by hematopoietic cell transplantation. Blood. 2004 Sep 01; 104(5):1298-305.
Traver D, Winzeler A, Stern HM, Mayhall EA, Langenau DM, Kutok JL, Look AT, Zon LI. PMID: 15142873.
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PubMed Mentions:
74 Fields:
Translation:
Animals
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In vivo tracking of T cell development, ablation, and engraftment in transgenic zebrafish. Proc Natl Acad Sci U S A. 2004 May 11; 101(19):7369-74.
Langenau DM, Ferrando AA, Traver D, Kutok JL, Hezel JP, Kanki JP, Zon LI, Look AT, Trede NS. PMID: 15123839; PMCID: PMC409925.
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PubMed Mentions:
189 Fields:
Translation:
AnimalsCells
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The use of zebrafish to understand immunity. Immunity. 2004 Apr; 20(4):367-79.
Trede NS, Langenau DM, Traver D, Look AT, Zon LI. PMID: 15084267.
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PubMed Mentions:
234 Fields:
Translation:
Animals
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The pu.1 promoter drives myeloid gene expression in zebrafish. Blood. 2004 Sep 01; 104(5):1291-7.
Hsu K, Traver D, Kutok JL, Hagen A, Liu TX, Paw BH, Rhodes J, Berman JN, Zon LI, Kanki JP, Look AT. PMID: 14996705.
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PubMed Mentions:
64 Fields:
Translation:
AnimalsCells
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Lineage commitment and developmental plasticity in early lymphoid progenitor subsets. Adv Immunol. 2004; 83:1-54.
Traver D, Akashi K. PMID: 15135627.
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PubMed Mentions:
5 Fields:
Translation:
HumansAnimalsCells
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Cellular dissection of zebrafish hematopoiesis. Methods Cell Biol. 2004; 76:127-49.
Traver D. PMID: 15602875.
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PubMed Mentions:
14 Fields:
Translation:
AnimalsCells
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Transplantation and in vivo imaging of multilineage engraftment in zebrafish bloodless mutants. Nat Immunol. 2003 Dec; 4(12):1238-46.
Traver D, Paw BH, Poss KD, Penberthy WT, Lin S, Zon LI. PMID: 14608381.
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PubMed Mentions:
424 Fields:
Translation:
AnimalsCells
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Expression of BCR/ABL and BCL-2 in myeloid progenitors leads to myeloid leukemias. Proc Natl Acad Sci U S A. 2003 Aug 19; 100(17):10002-7.
Jaiswal S, Traver D, Miyamoto T, Akashi K, Lagasse E, Weissman IL. PMID: 12890867; PMCID: PMC187741.
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PubMed Mentions:
53 Fields:
Translation:
HumansAnimalsCells
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Myc-induced T cell leukemia in transgenic zebrafish. Science. 2003 Feb 07; 299(5608):887-90.
Langenau DM, Traver D, Ferrando AA, Kutok JL, Aster JC, Kanki JP, Lin S, Prochownik E, Trede NS, Zon LI, Look AT. PMID: 12574629.
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PubMed Mentions:
231 Fields:
Translation:
AnimalsCells
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The zebrafish as a model organism to study development of the immune system. Adv Immunol. 2003; 81:253-330.
Traver D, Herbomel P, Patton EE, Murphey RD, Yoder JA, Litman GW, Catic A, Amemiya CT, Zon LI, Trede NS. PMID: 14711058.
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PubMed Mentions:
115 Fields:
Translation:
Animals
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Intrinsic requirement for zinc finger transcription factor Gfi-1 in neutrophil differentiation. Immunity. 2003 Jan; 18(1):109-20.
Hock H, Hamblen MJ, Rooke HM, Traver D, Bronson RT, Cameron S, Orkin SH. PMID: 12530980.
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PubMed Mentions:
191 Fields:
Translation:
AnimalsCells
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Expression of CD41 marks the initiation of definitive hematopoiesis in the mouse embryo. Blood. 2003 Jan 15; 101(2):508-16.
Mikkola HK, Fujiwara Y, Schlaeger TM, Traver D, Orkin SH. PMID: 12393529.
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PubMed Mentions:
144 Fields:
Translation:
AnimalsCells
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Myeloid progenitors protect against invasive aspergillosis and Pseudomonas aeruginosa infection following hematopoietic stem cell transplantation. Blood. 2002 Dec 15; 100(13):4660-7.
BitMansour A, Burns SM, Traver D, Akashi K, Contag CH, Weissman IL, Brown JM. PMID: 12393415.
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PubMed Mentions:
29 Fields:
Translation:
AnimalsCells
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Walking the walk: migration and other common themes in blood and vascular development. Cell. 2002 Mar 22; 108(6):731-4.
Traver D, Zon LI. PMID: 11955426.
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PubMed Mentions:
16 Fields:
Translation:
AnimalsCells