Pradipta Ghosh

Title(s)Professor, Cellular and Molecular Medicine
SchoolHealth Sciences
Address9500 Gilman Drive #0651
La Jolla CA 92093
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    Other Positions
    Title(s)Cellular and Molecular Medicine


    Collapse Biography 
    Collapse Education and Training
    Christian Medical College & HospitalMBBS (MD)2000Medicine
    Christian Medical College & HospitalResident Physician 2001
    Washington UniversityPostdoctoral2003Cell & Mol Biology
    UC San DiegoInternship Residency2005Internal Medicine
    UC San DiegoFellowship2008Gastroenterology
    UC San DiegoPostdoctoral2008Cell & Mol Biology

    Collapse Overview 

    Collapse Research 
    Collapse Research Activities and Funding
    Macrophage Polarization in Response to Infections and Inflammation
    NIH R01AI155696Sep 22, 2020 - Aug 31, 2025
    Role: Principal Investigator
    Precision therapeutics of inflammatory bowel disease guided by Boolean logic
    NIH UG3TR003355Aug 28, 2020 - Jul 31, 2023
    Role: Co-Principal Investigator
    Network-Based Novel Therapeutics in Colorectal Cancers
    NIH UG3TR002968Sep 11, 2019 - Jul 31, 2022
    Role: Principal Investigator
    Modulation of Macrophage Polarization by Heterotrimeric G proteins: Implications of Gastrointestinal Inflammation
    NIH R01AI141630May 21, 2019 - Apr 30, 2024
    Role: Principal Investigator
    Integrators of Metastatic Potential
    NIH R01CA238042Mar 1, 2019 - Feb 29, 2024
    Role: Principal Investigator
    G Protein pathways as Novel Therapeutic and Diagnostic Targets in Liver Fibrosis
    NIH R01DK099226Jul 1, 2014 - Jun 30, 2019
    Role: Principal Investigator
    Modulation of G proteins by Growth Factors
    NIH R01CA160911Feb 1, 2013 - Jan 31, 2020
    Role: Principal Investigator
    Spatial Regulation of RGS and G Protein Signaling
    NIH R01CA100768Apr 17, 2003 - Jan 31, 2021
    Role: Principal Investigator
    Training Grant in Gastroenterology
    NIH T32DK007202Jul 1, 1976 - Jun 30, 2023
    Role: Co-Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Building unconventional G protein-coupled receptors, one block at a time. Trends Pharmacol Sci. 2021 May 10. Ghosh P, Mullick M. PMID: 33985816.
      View in: PubMed   Mentions:    Fields:    
    2. The stress polarity signaling (SPS) pathway serves as a marker and a target in the leaky gut barrier: implications in aging and cancer. Life Sci Alliance. 2020 03; 3(3). Ghosh P, Swanson L, Sayed IM, Mittal Y, Lim BB, Ibeawuchi SR, Foretz M, Viollet B, Sahoo D, Das S. PMID: 32041849.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    3. Do All Roads Lead to Rome in G-Protein Activation? Trends Biochem Sci. 2020 03; 45(3):182-184. Ghosh P, Garcia-Marcos M. PMID: 31753703.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    4. Convergence of Wnt, growth factor, and heterotrimeric G protein signals on the guanine nucleotide exchange factor Daple. Sci Signal. 2018 02 27; 11(519). Aznar N, Ear J, Dunkel Y, Sun N, Satterfield K, He F, Kalogriopoulos NA, Lopez-Sanchez I, Ghassemian M, Sahoo D, Kufareva I, Ghosh P. PMID: 29487190.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    5. A Daple-Akt feed-forward loop enhances noncanonical Wnt signals by compartmentalizing ß-catenin. Mol Biol Cell. 2017 Dec 01; 28(25):3709-3723. Aznar N, Sun N, Dunkel Y, Ear J, Buschman MD, Ghosh P. PMID: 29021338.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    6. The untapped potential of tyrosine-based G protein signaling. Pharmacol Res. 2016 Mar; 105:99-107. Ghosh P. PMID: 26808081.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    7. Focal adhesions are foci for tyrosine-based signal transduction via GIV/Girdin and G proteins. Mol Biol Cell. 2015 Dec 01; 26(24):4313-24. Lopez-Sanchez I, Kalogriopoulos N, Lo IC, Kabir F, Midde KK, Wang H, Ghosh P. PMID: 26446841.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    8. Cyclin-dependent kinase 5 activates guanine nucleotide exchange factor GIV/Girdin to orchestrate migration-proliferation dichotomy. Proc Natl Acad Sci U S A. 2015 Sep 01; 112(35):E4874-83. Bhandari D, Lopez-Sanchez I, To A, Lo IC, Aznar N, Leyme A, Gupta V, Niesman I, Maddox AL, Garcia-Marcos M, Farquhar MG, Ghosh P. PMID: 26286990.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    9. GIV/Girdin is a rheostat that fine-tunes growth factor signals during tumor progression. Cell Adh Migr. 2011 May-Jun; 5(3):237-48. Ghosh P, Garcia-Marcos M, Farquhar MG. PMID: 21546796.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansAnimalsCells
    10. A G{alpha}i-GIV molecular complex binds epidermal growth factor receptor and determines whether cells migrate or proliferate. Mol Biol Cell. 2010 Jul 01; 21(13):2338-54. Ghosh P, Beas AO, Bornheimer SJ, Garcia-Marcos M, Forry EP, Johannson C, Ear J, Jung BH, Cabrera B, Carethers JM, Farquhar MG. PMID: 20462955.
      View in: PubMed   Mentions: 80     Fields:    Translation:HumansCells
    11. Gastric adenocarcinoma inducing portal hypertension: a rare presentation. World J Gastroenterol. 2007 Feb 14; 13(6):960-3. Ghosh P, Miyai K, Chojkier M. PMID: 17352032.
      View in: PubMed   Mentions:    Fields:    Translation:Humans