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Arshad Desai

Title(s)Professor, Cell and Developmental Biology
SchoolVc-academic Affairs
Address9500 Gilman Drive #
La Jolla CA 92093
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    Our lab is interested in understanding how the replicated genome is accurately segregated during cell division.

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Polo-like kinase 1 independently controls microtubule-nucleating capacity and size of the centrosome. J Cell Biol. 2021 Feb 01; 220(2). Ohta M, Zhao Z, Wu D, Wang S, Harrison JL, Gómez-Cavazos JS, Desai A, Oegema KF. PMID: 33399854.
      View in: PubMed   Mentions:    Fields:    
    2. The PHLPP1 N-Terminal Extension is a Mitotic Cdk1 Substrate and Controls an Interactome Switch. Mol Cell Biol. 2021 Jan 04. Kawashima AT, Wong C, Lordén G, King CC, Lara-Gonzalez P, Desai A, Gingras AC, Newton AC. PMID: 33397691.
      View in: PubMed   Mentions:    Fields:    
    3. A tripartite mechanism catalyzes Mad2-Cdc20 assembly at unattached kinetochores. Science. 2021 Jan 01; 371(6524):64-67. Lara-Gonzalez P, Kim T, Oegema K, Corbett K, Desai A. PMID: 33384372.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    4. Centriole-independent mitotic spindle assembly relies on the PCNT-CDK5RAP2 pericentriolar matrix. J Cell Biol. 2020 Dec 07; 219(12). Watanabe S, Meitinger F, Shiau AK, Oegema K, Desai A. PMID: 33170211.
      View in: PubMed   Mentions: 1     Fields:    
    5. TRIM37 controls cancer-specific vulnerability to PLK4 inhibition. Nature. 2020 09; 585(7825):440-446. Meitinger F, Ohta M, Lee KY, Watanabe S, Davis RL, Anzola JV, Kabeche R, Jenkins DA, Shiau AK, Desai A, Oegema K. PMID: 32908304.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    6. Rashomon at the kinetochore: Function(s) of the Mad1-cyclin B1 complex. J Cell Biol. 2020 Aug 03; 219(8). Houston J, Lara-Gonzalez P, Desai A. PMID: 32614383.
      View in: PubMed   Mentions:    Fields:    
    7. A Non-canonical BRCT-Phosphopeptide Recognition Mechanism Underlies RhoA Activation in Cytokinesis. Curr Biol. 2020 Aug 17; 30(16):3101-3115.e11. Gómez-Cavazos JS, Lee KY, Lara-González P, Li Y, Desai A, Shiau AK, Oegema K. PMID: 32619481.
      View in: PubMed   Mentions:    Fields:    
    8. A Semi-high-throughput Imaging Method and Data Visualization Toolkit to Analyze C. elegans Embryonic Development. J Vis Exp. 2019 10 29; (152). Khaliullin RN, Hendel JM, Gerson-Gurwitz A, Wang S, Ochoa SD, Zhao Z, Desai A, Oegema K, Green RA. PMID: 31736498.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    9. The G2-to-M Transition Is Ensured by a Dual Mechanism that Protects Cyclin B from Degradation by Cdc20-Activated APC/C. Dev Cell. 2019 11 04; 51(3):313-325.e10. Lara-Gonzalez P, Moyle MW, Budrewicz J, Mendoza-Lopez J, Oegema K, Desai A. PMID: 31588029.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    10. Ancestral roles of the Fam20C family of secreted protein kinases revealed in C. elegans. J Cell Biol. 2019 11 04; 218(11):3795-3811. Gerson-Gurwitz A, Worby CA, Lee KY, Khaliullin R, Bouffard J, Cheerambathur D, Oegema K, Cram EJ, Dixon JE, Desai A. PMID: 31541016.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    11. Unbiased Boolean analysis of public gene expression data for cell cycle gene identification. Mol Biol Cell. 2019 07 01; 30(14):1770-1779. Dabydeen SA, Desai A, Sahoo D. PMID: 31091168.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    12. A high-content imaging approach to profile C. elegans embryonic development. Development. 2019 04 11; 146(7). Wang S, Ochoa SD, Khaliullin RN, Gerson-Gurwitz A, Hendel JM, Zhao Z, Biggs R, Chisholm AD, Desai A, Oegema K, Green RA. PMID: 30890570.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    13. Pharmacological convergence reveals a lipid pathway that regulates C. elegans lifespan. Nat Chem Biol. 2019 05; 15(5):453-462. Chen AL, Lum KM, Lara-Gonzalez P, Ogasawara D, Cognetta AB, To A, Parsons WH, Simon GM, Desai A, Petrascheck M, Bar-Peled L, Cravatt BF. PMID: 30911178.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    14. The Kinetochore-Microtubule Coupling Machinery Is Repurposed in Sensory Nervous System Morphogenesis. Dev Cell. 2019 03 25; 48(6):864-872.e7. Cheerambathur DK, Prevo B, Chow TL, Hattersley N, Wang S, Zhao Z, Kim T, Gerson-Gurwitz A, Oegema K, Green R, Desai A. PMID: 30827898.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    15. CFI-400945 is not a selective cellular PLK4 inhibitor. Proc Natl Acad Sci U S A. 2018 11 13; 115(46):E10808-E10809. Oegema K, Davis RL, Lara-Gonzalez P, Desai A, Shiau AK. PMID: 30377272.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    16. Promoting an "Auteur Theory" for Young Scientists: Preserving Excitement and Creativity?…. Bioessays. 2018 11; 40(11):e1800147. Desai A, Jun S. PMID: 30238592.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    17. CYK-4 functions independently of its centralspindlin partner ZEN-4 to cellularize oocytes in germline syncytia. Elife. 2018 07 10; 7. Lee KY, Green RA, Gutierrez E, Gomez-Cavazos JS, Kolotuev I, Wang S, Desai A, Groisman A, Oegema K. PMID: 29989548.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    18. A positive-feedback-based mechanism for constriction rate acceleration during cytokinesis in Caenorhabditis elegans. Elife. 2018 07 02; 7. Khaliullin RN, Green RA, Shi LZ, Gomez-Cavazos JS, Berns MW, Desai A, Oegema K. PMID: 29963981.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    19. Employing the one-cell C. elegans embryo to study cell division processes. Methods Cell Biol. 2018; 144:185-231. PMID: 29804670.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    20. Analyzing the micromechanics of the cell division apparatus. Methods Cell Biol. 2018; 145:173-190. Shimamoto Y, Kapoor TM. PMID: 29957203.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    21. Cdc73 suppresses genome instability by mediating telomere homeostasis. PLoS Genet. 2018 01; 14(1):e1007170. PMID: 29320491.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    22. Meiosis: The Origins of Bias. Curr Biol. 2017 12 18; 27(24):R1309-R1311. Kim T, Desai A. PMID: 29257963.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    23. Taming the Beast: Control of APC/CCdc20-Dependent Destruction. Cold Spring Harb Symp Quant Biol. 2017; 82:111-121. Lara-Gonzalez P, Kim T, Desai A. PMID: 29133301.
      View in: PubMed   Mentions:    Fields:    
    24. Channel Nucleoporins Recruit PLK-1 to Nuclear Pore Complexes to Direct Nuclear Envelope Breakdown in C. elegans. Dev Cell. 2017 10 23; 43(2):157-171.e7. Martino L, Morchoisne-Bolhy S, Cheerambathur DK, Van Hove L, Dumont J, Joly N, Desai A, Doye V, Pintard L. PMID: 29065307.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    25. Chromosome Mis-segregation Generates Cell-Cycle-Arrested Cells with Complex Karyotypes that Are Eliminated by the Immune System. Dev Cell. 2017 06 19; 41(6):638-651.e5. PMID: 28633018.
      View in: PubMed   Mentions: 36     Fields:    Translation:Humans
    26. A toolkit for GFP-mediated tissue-specific protein degradation in C. elegans. Development. 2017 07 15; 144(14):2694-2701. Wang S, Tang NH, Lara-Gonzalez P, Zhao Z, Cheerambathur DK, Prevo B, Chisholm AD, Desai A, Oegema K. PMID: 28619826.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    27. Kinetochores accelerate or delay APC/C activation by directing Cdc20 to opposing fates. Genes Dev. 2017 06 01; 31(11):1089-1094. PMID: 28698300.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    28. Dephosphorylation of the Ndc80 Tail Stabilizes Kinetochore-Microtubule Attachments via the Ska Complex. Dev Cell. 2017 05 22; 41(4):424-437.e4. PMID: 28535376.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    29. An engineered minimal chromosomal passenger complex reveals a role for INCENP/Sli15 spindle association in chromosome biorientation. J Cell Biol. 2017 04 03; 216(4):911-923. PMID: 28314741.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    30. Cell cycle, cell division, and cell death. Mol Biol Cell. 2017 03 15; 28(6):693-694. PMID: 28292908.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    31. How centrioles acquire the ability to reproduce. Elife. 2017 03 08; 6. PMID: 28271993.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    32. A Molecular View of Kinetochore Assembly and Function. Biology (Basel). 2017 Jan 24; 6(1). PMID: 28125021.
      View in: PubMed   Mentions:
    33. The nucleoporin MEL-28/ELYS: A PP1 scaffold during M-phase exit. . 2017 03 19; 16(6):489-490. PMID: 28102742.
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    34. A Nucleoporin Docks Protein Phosphatase 1 to Direct Meiotic Chromosome Segregation and Nuclear Assembly. Dev Cell. 2016 09 12; 38(5):463-77. PMID: 27623381.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    35. 53BP1 and USP28 mediate p53 activation and G1 arrest after centrosome loss or extended mitotic duration. J Cell Biol. 2016 07 18; 214(2):155-66. PMID: 27432897.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansCells
    36. A TOGgle for Tension at Kinetochores. Cell. 2016 Jun 02; 165(6):1316-1318. PMID: 27259144.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    37. A Small RNA-Catalytic Argonaute Pathway Tunes Germline Transcript Levels to Ensure Embryonic Divisions. Cell. 2016 Apr 07; 165(2):396-409. PMID: 27020753.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    38. Correction: Kinetochore-localized BUB-1/BUB-3 complex promotes anaphase onset in C. elegans. J Cell Biol. 2016 Mar 14; 212(6):737. PMID: 26953348.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    39. A Cell Biologist's Field Guide to Aurora Kinase Inhibitors. Front Oncol. 2015; 5:285. PMID: 26732741.
      View in: PubMed   Mentions:
    40. NOCA-1 functions with ?-tubulin and in parallel to Patronin to assemble non-centrosomal microtubule arrays in C. elegans. Elife. 2015 Sep 15; 4:e08649. Wang S, Wu D, Quintin S, Green RA, Cheerambathur DK, Ochoa SD, Desai A, Oegema K. PMID: 26371552.
      View in: PubMed   Mentions: 35     Fields:    Translation:AnimalsCells
    41. Natural Loss of Mps1 Kinase in Nematodes Uncovers a Role for Polo-like Kinase 1 in Spindle Checkpoint Initiation. Cell Rep. 2015 Jul 07; 12(1):58-65. PMID: 26119738.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    42. Orthogonal targeting of EGFRvIII expressing glioblastomas through simultaneous EGFR and PLK1 inhibition. Oncotarget. 2015 May 20; 6(14):11751-67. PMID: 26059434.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    43. Kinetochore-localized BUB-1/BUB-3 complex promotes anaphase onset in C. elegans. J Cell Biol. 2015 May 25; 209(4):507-17. PMID: 25987605.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    44. Cell biology. Reversible centriole depletion with an inhibitor of Polo-like kinase 4. Science. 2015 Jun 05; 348(6239):1155-60. PMID: 25931445.
      View in: PubMed   Mentions: 104     Fields:    Translation:HumansAnimalsCells
    45. Separase Cleaves the N-Tail of the CENP-A Related Protein CPAR-1 at the Meiosis I Metaphase-Anaphase Transition in C. elegans. PLoS One. 2015; 10(4):e0125382. PMID: 25919583.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    46. Preventing farnesylation of the dynein adaptor Spindly contributes to the mitotic defects caused by farnesyltransferase inhibitors. Mol Biol Cell. 2015 May 15; 26(10):1845-56. PMID: 25808490.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    47. The CENP-A N-tail confers epigenetic stability to centromeres via the CENP-T branch of the CCAN in fission yeast. Curr Biol. 2015 Feb 02; 25(3):348-356. PMID: 25619765.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    48. The outer kinetochore protein KNL-1 contains a defined oligomerization domain in nematodes. Mol Biol Cell. 2015 Jan 15; 26(2):229-37. PMID: 25411336.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    49. A new piece in the kinetochore jigsaw puzzle. J Cell Biol. 2014 Aug 18; 206(4):457-9. PMID: 25135931.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    50. PCNA and Msh2-Msh6 activate an Mlh1-Pms1 endonuclease pathway required for Exo1-independent mismatch repair. Mol Cell. 2014 Jul 17; 55(2):291-304. PMID: 24981171.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    51. Mlh2 is an accessory factor for DNA mismatch repair in Saccharomyces cerevisiae. PLoS Genet. 2014 May; 10(5):e1004327. PMID: 24811092.
      View in: PubMed   Mentions: 11     Fields:    Translation:Animals
    52. A Bub1-Mad1 interaction targets the Mad1-Mad2 complex to unattached kinetochores to initiate the spindle checkpoint. J Cell Biol. 2014 Mar 03; 204(5):647-57. PMID: 24567362.
      View in: PubMed   Mentions: 50     Fields:    Translation:AnimalsCells
    53. Spatial control of phospholipid flux restricts endoplasmic reticulum sheet formation to allow nuclear envelope breakdown. Genes Dev. 2014 Jan 15; 28(2):121-6. PMID: 24449268.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    54. Linked in: formation and regulation of microtubule attachments during chromosome segregation. Curr Opin Cell Biol. 2014 Feb; 26:113-22. PMID: 24529253.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    55. Meiotic double-strand breaks uncover and protect against mitotic errors in the C. elegans germline. Curr Biol. 2013 Dec 02; 23(23):2400-6. PMID: 24239117.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    56. Crosstalk between microtubule attachment complexes ensures accurate chromosome segregation. Science. 2013 Dec 06; 342(6163):1239-42. PMID: 24231804.
      View in: PubMed   Mentions: 35     Fields:    Translation:AnimalsCells
    57. The midbody ring scaffolds the abscission machinery in the absence of midbody microtubules. J Cell Biol. 2013 Nov 11; 203(3):505-20. PMID: 24217623.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    58. Dominant mutations in S. cerevisiae PMS1 identify the Mlh1-Pms1 endonuclease active site and an exonuclease 1-independent mismatch repair pathway. PLoS Genet. 2013 Oct; 9(10):e1003869. PMID: 24204293.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    59. A conserved RhoGAP limits M phase contractility and coordinates with microtubule asters to confine RhoA during cytokinesis. Dev Cell. 2013 Sep 16; 26(5):496-510. PMID: 24012485.
      View in: PubMed   Mentions: 35     Fields:    Translation:AnimalsCells
    60. Spindle assembly checkpoint proteins are positioned close to core microtubule attachment sites at kinetochores. J Cell Biol. 2013 Sep 02; 202(5):735-46. PMID: 23979716.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansAnimalsCells
    61. A two-step mechanism for epigenetic specification of centromere identity and function. Nat Cell Biol. 2013 Sep; 15(9):1056-66. PMID: 23873148.
      View in: PubMed   Mentions: 106     Fields:    Translation:HumansAnimalsCells
    62. Direct binding of SAS-6 to ZYG-1 recruits SAS-6 to the mother centriole for cartwheel assembly. Dev Cell. 2013 May 13; 25(3):284-98. PMID: 23673331.
      View in: PubMed   Mentions: 31     Fields:    Translation:AnimalsCells
    63. Tension sensing by Aurora B kinase is independent of survivin-based centromere localization. Nature. 2013 May 02; 497(7447):118-21. PMID: 23604256.
      View in: PubMed   Mentions: 62     Fields:    Translation:AnimalsCells
    64. What the hec is up with mouse oocyte meiosis? Dev Cell. 2013 Apr 15; 25(1):3-4. PMID: 23597481.
      View in: PubMed   Mentions:    Fields:    
    65. Hierarchical assembly of the eggshell and permeability barrier in C. elegans. J Cell Biol. 2012 Aug 20; 198(4):731-48. PMID: 22908315.
      View in: PubMed   Mentions: 40     Fields:    Translation:AnimalsCells
    66. An inverse relationship to germline transcription defines centromeric chromatin in C. elegans. Nature. 2012 Apr 08; 484(7395):534-7. PMID: 22495302.
      View in: PubMed   Mentions: 63     Fields:    Translation:AnimalsCells
    67. Acentrosomal spindle assembly and chromosome segregation during oocyte meiosis. Trends Cell Biol. 2012 May; 22(5):241-9. PMID: 22480579.
      View in: PubMed   Mentions: 58     Fields:    Translation:HumansAnimalsCells
    68. Microtubule binding by KNL-1 contributes to spindle checkpoint silencing at the kinetochore. J Cell Biol. 2012 Feb 20; 196(4):469-82. PMID: 22331849.
      View in: PubMed   Mentions: 50     Fields:    Translation:AnimalsCells
    69. Structure, assembly and reading of centromeric chromatin. Curr Opin Genet Dev. 2012 Apr; 22(2):139-47. PMID: 22178421.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    70. Visualization of eukaryotic DNA mismatch repair reveals distinct recognition and repair intermediates. Cell. 2011 Nov 23; 147(5):1040-53. PMID: 22118461.
      View in: PubMed   Mentions: 99     Fields:    Translation:HumansAnimalsCells
    71. Rapid de novo centromere formation occurs independently of heterochromatin protein 1 in C. elegans embryos. Curr Biol. 2011 Nov 08; 21(21):1800-7. PMID: 22018540.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    72. Acute drug treatment in the early C. elegans embryo. PLoS One. 2011; 6(9):e24656. Carvalho A, Olson SK, Gutierrez E, Zhang K, Noble LB, Zanin E, Desai A, Groisman A, Oegema K. PMID: 21935434.
      View in: PubMed   Mentions: 49     Fields:    Translation:Animals
    73. Uncoordinated loss of chromatid cohesion is a common outcome of extended metaphase arrest. PLoS One. 2011; 6(8):e22969. Stevens D, Gassmann R, Oegema K, Desai A. PMID: 21829677.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansCells
    74. A high-resolution C. elegans essential gene network based on phenotypic profiling of a complex tissue. Cell. 2011 Apr 29; 145(3):470-82. PMID: 21529718.
      View in: PubMed   Mentions: 96     Fields:    Translation:Animals
    75. The chromosomal passenger complex and centralspindlin independently contribute to contractile ring assembly. J Cell Biol. 2011 Apr 04; 193(1):155-69. Lewellyn L, Carvalho A, Desai A, Maddox AS, Oegema K. PMID: 21464231.
      View in: PubMed   Mentions: 35     Fields:    Translation:AnimalsCells
    76. Affinity purification of protein complexes in C. elegans. Methods Cell Biol. 2011; 106:289-322. PMID: 22118282.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    77. Broad chromosomal domains of histone modification patterns in C. elegans. Genome Res. 2011 Feb; 21(2):227-36. Liu T, Rechtsteiner A, Egelhofer TA, Vielle A, Latorre I, Cheung MS, Ercan S, Ikegami K, Jensen M, Kolasinska-Zwierz P, Rosenbaum H, Shin H, Taing S, Takasaki T, Iniguez AL, Desai A, Dernburg AF, Kimura H, Lieb JD, Ahringer J, Strome S, Liu XS. PMID: 21177964.
      View in: PubMed   Mentions: 130     Fields:    Translation:AnimalsCells
    78. Integrative analysis of the Caenorhabditis elegans genome by the modENCODE project. Science. 2010 Dec 24; 330(6012):1775-87. Gerstein MB, Lu ZJ, Van Nostrand EL, Cheng C, Arshinoff BI, Liu T, Yip KY, Robilotto R, Rechtsteiner A, Ikegami K, Alves P, Chateigner A, Perry M, Morris M, Auerbach RK, Feng X, Leng J, Vielle A, Niu W, Rhrissorrakrai K, Agarwal A, Alexander RP, Barber G, Brdlik CM, Brennan J, Brouillet JJ, Carr A, Cheung MS, Clawson H, Contrino S, Dannenberg LO, Dernburg AF, Desai A, Dick L, Dosé AC, Du J, Egelhofer T, Ercan S, Euskirchen G, Ewing B, Feingold EA, Gassmann R, Good PJ, Green P, Gullier F, Gutwein M, Guyer MS, Habegger L, Han T, Henikoff JG, Henz SR, Hinrichs A, Holster H, Hyman T, Iniguez AL, Janette J, Jensen M, Kato M, Kent WJ, Kephart E, Khivansara V, Khurana E, Kim JK, Kolasinska-Zwierz P, Lai EC, Latorre I, Leahey A, Lewis S, Lloyd P, Lochovsky L, Lowdon RF, Lubling Y, Lyne R, MacCoss M, Mackowiak SD, Mangone M, McKay S, Mecenas D, Merrihew G, Miller DM, Muroyama A, Murray JI, Ooi SL, Pham H, Phippen T, Preston EA, Rajewsky N, Rätsch G, Rosenbaum H, Rozowsky J, Rutherford K, Ruzanov P, Sarov M, Sasidharan R, Sboner A, Scheid P, Segal E, Shin H, Shou C, Slack FJ, Slightam C, Smith R, Spencer WC, Stinson EO, Taing S, Takasaki T, Vafeados D, Voronina K, Wang G, Washington NL, Whittle CM, Wu B, Yan KK, Zeller G, Zha Z, Zhong M, Zhou X, Ahringer J, Strome S, Gunsalus KC, Micklem G, Liu XS, Reinke V, Kim SK, Hillier LW, Henikoff S, Piano F, Snyder M, Stein L, Lieb JD, Waterston RH. PMID: 21177976.
      View in: PubMed   Mentions: 479     Fields:    Translation:AnimalsCells
    79. A PSHaver for centromeric histones. Mol Cell. 2010 Nov 12; 40(3):351-2. Folco HD, Desai A. PMID: 21070962.
      View in: PubMed   Mentions: 2     Fields:    
    80. A kinetochore-independent mechanism drives anaphase chromosome separation during acentrosomal meiosis. Nat Cell Biol. 2010 Sep; 12(9):894-901. Dumont J, Oegema K, Desai A. PMID: 20729837.
      View in: PubMed   Mentions: 75     Fields:    Translation:AnimalsCells
    81. PHF8 mediates histone H4 lysine 20 demethylation events involved in cell cycle progression. Nature. 2010 Jul 22; 466(7305):508-12. Liu W, Tanasa B, Tyurina OV, Zhou TY, Gassmann R, Liu WT, Ohgi KA, Benner C, Garcia-Bassets I, Aggarwal AK, Desai A, Dorrestein PC, Glass CK, Rosenfeld MG. PMID: 20622854.
      View in: PubMed   Mentions: 166     Fields:    Translation:HumansCells
    82. Removal of Spindly from microtubule-attached kinetochores controls spindle checkpoint silencing in human cells. Genes Dev. 2010 May; 24(9):957-71. Gassmann R, Holland AJ, Varma D, Wan X, Civril F, Cleveland DW, Oegema K, Salmon ED, Desai A. PMID: 20439434.
      View in: PubMed   Mentions: 80     Fields:    Translation:HumansCells
    83. Cell structure and dynamics. Curr Opin Cell Biol. 2010 Feb; 22(1):1-3. Desai A, Dogterom M. PMID: 20102790.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    84. Analyzing the effects of delaying aster separation on furrow formation during cytokinesis in the Caenorhabditis elegans embryo. Mol Biol Cell. 2010 Jan 01; 21(1):50-62. Lewellyn L, Dumont J, Desai A, Oegema K. PMID: 19889842.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    85. The hydrolethalus syndrome protein HYLS-1 links core centriole structure to cilia formation. Genes Dev. 2009 Sep 01; 23(17):2046-59. Dammermann A, Pemble H, Mitchell BJ, McLeod I, Yates JR, Kintner C, Desai AB, Oegema K. PMID: 19656802.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimalsCells
    86. Structural memory in the contractile ring makes the duration of cytokinesis independent of cell size. Cell. 2009 May 29; 137(5):926-37. Carvalho A, Desai A, Oegema K. PMID: 19490897.
      View in: PubMed   Mentions: 88     Fields:    Translation:Animals
    87. Protein architecture of the human kinetochore microtubule attachment site. Cell. 2009 May 15; 137(4):672-84. Wan X, O'Quinn RP, Pierce HL, Joglekar AP, Gall WE, DeLuca JG, Carroll CW, Liu ST, Yen TJ, McEwen BF, Stukenberg PT, Desai A, Salmon ED. PMID: 19450515.
      View in: PubMed   Mentions: 198     Fields:    Translation:HumansCells
    88. Systematic analysis in Caenorhabditis elegans reveals that the spindle checkpoint is composed of two largely independent branches. Mol Biol Cell. 2009 Feb; 20(4):1252-67. Essex A, Dammermann A, Lewellyn L, Oegema K, Desai A. PMID: 19109417.
      View in: PubMed   Mentions: 39     Fields:    Translation:AnimalsCells
    89. Inhibition of Rac by the GAP activity of centralspindlin is essential for cytokinesis. Science. 2008 Dec 05; 322(5907):1543-6. Canman JC, Lewellyn L, Laband K, Smerdon SJ, Desai A, Bowerman B, Oegema K. PMID: 19056985.
      View in: PubMed   Mentions: 75     Fields:    Translation:AnimalsCells
    90. Fibrils connect microtubule tips with kinetochores: a mechanism to couple tubulin dynamics to chromosome motion. Cell. 2008 Oct 17; 135(2):322-33. McIntosh JR, Grishchuk EL, Morphew MK, Efremov AK, Zhudenkov K, Volkov VA, Cheeseman IM, Desai A, Mastronarde DN, Ataullakhanov FI. PMID: 18957206.
      View in: PubMed   Mentions: 102     Fields:    Translation:AnimalsCells
    91. Orientation and structure of the Ndc80 complex on the microtubule lattice. J Cell Biol. 2008 Sep 22; 182(6):1055-61. Wilson-Kubalek EM, Cheeseman IM, Yoshioka C, Desai A, Milligan RA. PMID: 18794333.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansCells
    92. An integrated mechanobiochemical feedback mechanism describes chromosome motility from prometaphase to anaphase in mitosis. Proc Natl Acad Sci U S A. 2008 Sep 16; 105(37):13752-7. Liu J, Desai A, Onuchic JN, Hwa T. PMID: 18780795.
      View in: PubMed   Mentions: 7     Fields:    Translation:Cells
    93. A new mechanism controlling kinetochore-microtubule interactions revealed by comparison of two dynein-targeting components: SPDL-1 and the Rod/Zwilch/Zw10 complex. Genes Dev. 2008 Sep 01; 22(17):2385-99. Gassmann R, Essex A, Hu JS, Maddox PS, Motegi F, Sugimoto A, O'Rourke SM, Bowerman B, McLeod I, Yates JR, Oegema K, Cheeseman IM, Desai A. PMID: 18765790.
      View in: PubMed   Mentions: 84     Fields:    Translation:AnimalsCells
    94. Proteomics in Caenorhabditis elegans. Brief Funct Genomic Proteomic. 2008 May; 7(3):205-10. Audhya A, Desai A. PMID: 18372286.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    95. SAS-4 is recruited to a dynamic structure in newly forming centrioles that is stabilized by the gamma-tubulin-mediated addition of centriolar microtubules. J Cell Biol. 2008 Feb 25; 180(4):771-85. Dammermann A, Maddox PS, Desai A, Oegema K. PMID: 18299348.
      View in: PubMed   Mentions: 59     Fields:    Translation:AnimalsCells
    96. The wages of CIN. J Cell Biol. 2008 Feb 25; 180(4):661-3. Yuen KW, Desai A. PMID: 18283117.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    97. Kinetochore-microtubule interactions: the means to the end. Curr Opin Cell Biol. 2008 Feb; 20(1):53-63. Tanaka TU, Desai A. PMID: 18182282.
      View in: PubMed   Mentions: 59     Fields:    Translation:HumansAnimalsCells
    98. Expression and imaging of fluorescent proteins in the C. elegans gonad and early embryo. Methods Cell Biol. 2008; 85:179-218. Green RA, Audhya A, Pozniakovsky A, Dammermann A, Pemble H, Monen J, Portier N, Hyman A, Desai A, Oegema K. PMID: 18155464.
      View in: PubMed   Mentions: 35     Fields:    Translation:Animals
    99. Molecular architecture of the kinetochore-microtubule interface. Nat Rev Mol Cell Biol. 2008 Jan; 9(1):33-46. Cheeseman IM, Desai A. PMID: 18097444.
      View in: PubMed   Mentions: 427     Fields:    Translation:HumansAnimalsCells
    100. KNL1 and the CENP-H/I/K complex coordinately direct kinetochore assembly in vertebrates. Mol Biol Cell. 2008 Feb; 19(2):587-94. Cheeseman IM, Hori T, Fukagawa T, Desai A. PMID: 18045986.
      View in: PubMed   Mentions: 85     Fields:    Translation:HumansAnimalsCells
    101. A mechanobiochemical mechanism for monooriented chromosome oscillation in mitosis. Proc Natl Acad Sci U S A. 2007 Oct 09; 104(41):16104-9. Liu J, Desai A, Onuchic JN, Hwa T. PMID: 17911248.
      View in: PubMed   Mentions: 8     Fields:    Translation:Cells
    102. When it comes to couple(r)s, do opposites attract? Nat Struct Mol Biol. 2007 Sep; 14(9):790-2. Sandall S, Desai A. PMID: 17823608.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    103. A role for Rab5 in structuring the endoplasmic reticulum. J Cell Biol. 2007 Jul 02; 178(1):43-56. Audhya A, Desai A, Oegema K. PMID: 17591921.
      View in: PubMed   Mentions: 94     Fields:    Translation:AnimalsCells
    104. Anillin and the septins promote asymmetric ingression of the cytokinetic furrow. Dev Cell. 2007 May; 12(5):827-35. Maddox AS, Lewellyn L, Desai A, Oegema K. PMID: 17488632.
      View in: PubMed   Mentions: 64     Fields:    Translation:Animals
    105. A microtubule-independent role for centrosomes and aurora a in nuclear envelope breakdown. Dev Cell. 2007 Apr; 12(4):515-29. Portier N, Audhya A, Maddox PS, Green RA, Dammermann A, Desai A, Oegema K. PMID: 17419991.
      View in: PubMed   Mentions: 55     Fields:    Translation:AnimalsCells
    106. Functional genomics identifies a Myb domain-containing protein family required for assembly of CENP-A chromatin. J Cell Biol. 2007 Mar 12; 176(6):757-63. Maddox PS, Hyndman F, Monen J, Oegema K, Desai A. PMID: 17339379.
      View in: PubMed   Mentions: 101     Fields:    Translation:AnimalsCells
    107. Analysis of kinetochore assembly and function in Caenorhabditis elegans embryos and human cells. Methods. 2007 Feb; 41(2):177-89. Gassmann R, Kline SL, Carvalho A, Desai A. PMID: 17189860.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    108. Centromere identity maintained by nucleosomes assembled with histone H3 containing the CENP-A targeting domain. Mol Cell. 2007 Jan 26; 25(2):309-22. Black BE, Jansen LE, Maddox PS, Foltz DR, Desai AB, Shah JV, Cleveland DW. PMID: 17244537.
      View in: PubMed   Mentions: 119     Fields:    Translation:HumansAnimalsCells
    109. A Bir1-Sli15 complex connects centromeres to microtubules and is required to sense kinetochore tension. Cell. 2006 Dec 15; 127(6):1179-91. Sandall S, Severin F, McLeod IX, Yates JR, Oegema K, Hyman A, Desai A. PMID: 17174893.
      View in: PubMed   Mentions: 66     Fields:    Translation:AnimalsCells
    110. The conserved KMN network constitutes the core microtubule-binding site of the kinetochore. Cell. 2006 Dec 01; 127(5):983-97. Cheeseman IM, Chappie JS, Wilson-Kubalek EM, Desai A. PMID: 17129783.
      View in: PubMed   Mentions: 461     Fields:    Translation:HumansAnimalsCells
    111. An FHA domain-mediated protein interaction network of Rad53 reveals its role in polarized cell growth. J Cell Biol. 2006 Dec 04; 175(5):743-53. Smolka MB, Chen SH, Maddox PS, Enserink JM, Albuquerque CP, Wei XX, Desai A, Kolodner RD, Zhou H. PMID: 17130285.
      View in: PubMed   Mentions: 52     Fields:    Translation:AnimalsCells
    112. Molecular analysis of mitotic chromosome condensation using a quantitative time-resolved fluorescence microscopy assay. Proc Natl Acad Sci U S A. 2006 Oct 10; 103(41):15097-102. Maddox PS, Portier N, Desai A, Oegema K. PMID: 17005720.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    113. The CENP-H-I complex is required for the efficient incorporation of newly synthesized CENP-A into centromeres. Nat Cell Biol. 2006 May; 8(5):446-57. Okada M, Cheeseman IM, Hori T, Okawa K, McLeod IX, Yates JR, Desai A, Fukagawa T. PMID: 16622420.
      View in: PubMed   Mentions: 209     Fields:    Translation:HumansAnimalsCells
    114. The human Mis12 complex is required for kinetochore assembly and proper chromosome segregation. J Cell Biol. 2006 Apr 10; 173(1):9-17. Kline SL, Cheeseman IM, Hori T, Fukagawa T, Desai A. PMID: 16585270.
      View in: PubMed   Mentions: 102     Fields:    Translation:HumansAnimalsCells
    115. Analysis of microtubule polymerization in vitro and during the cell cycle in Xenopus egg extracts. Methods. 2006 Jan; 38(1):29-34. Budde PP, Desai A, Heald R. PMID: 16343934.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    116. Differential role of CENP-A in the segregation of holocentric C. elegans chromosomes during meiosis and mitosis. Nat Cell Biol. 2005 Dec; 7(12):1248-55. Monen J, Maddox PS, Hyndman F, Oegema K, Desai A. PMID: 16273096.
      View in: PubMed   Mentions: 86     Fields:    Translation:AnimalsCells
    117. Unstable microtubule capture at kinetochores depleted of the centromere-associated protein CENP-F. EMBO J. 2005 Nov 16; 24(22):3927-39. Bomont P, Maddox P, Shah JV, Desai AB, Cleveland DW. PMID: 16252009.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansAnimalsCells
    118. A complex containing the Sm protein CAR-1 and the RNA helicase CGH-1 is required for embryonic cytokinesis in Caenorhabditis elegans. J Cell Biol. 2005 Oct 24; 171(2):267-79. Audhya A, Hyndman F, McLeod IX, Maddox AS, Yates JR, Desai A, Oegema K. PMID: 16247027.
      View in: PubMed   Mentions: 109     Fields:    Translation:AnimalsCells
    119. Microtubule capture by CENP-E silences BubR1-dependent mitotic checkpoint signaling. J Cell Biol. 2005 Sep 12; 170(6):873-80. Mao Y, Desai A, Cleveland DW. PMID: 16144904.
      View in: PubMed   Mentions: 67     Fields:    Translation:HumansAnimalsCells
    120. An essential function of the C. elegans ortholog of TPX2 is to localize activated aurora A kinase to mitotic spindles. Dev Cell. 2005 Aug; 9(2):237-48. Ozlü N, Srayko M, Kinoshita K, Habermann B, O'toole ET, Müller-Reichert T, Schmalz N, Desai A, Hyman AA. PMID: 16054030.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansAnimalsCells
    121. Distinct roles for two C. elegans anillins in the gonad and early embryo. Development. 2005 Jun; 132(12):2837-48. Maddox AS, Habermann B, Desai A, Oegema K. PMID: 15930113.
      View in: PubMed   Mentions: 68     Fields:    Translation:AnimalsCells
    122. The CENP-F-like proteins HCP-1 and HCP-2 target CLASP to kinetochores to mediate chromosome segregation. Curr Biol. 2005 Apr 26; 15(8):771-7. Cheeseman IM, MacLeod I, Yates JR, Oegema K, Desai A. PMID: 15854912.
      View in: PubMed   Mentions: 38     Fields:    Translation:AnimalsCells
    123. Microtubule cytoskeleton: a new twist at the end. Curr Biol. 2005 Feb 22; 15(4):R126-9. Wittmann T, Desai A. PMID: 15723782.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    124. Kinetochore-spindle microtubule interactions during mitosis. Curr Opin Cell Biol. 2005 Feb; 17(1):35-46. Kline-Smith SL, Sandall S, Desai A. PMID: 15661517.
      View in: PubMed   Mentions: 51     Fields:    Translation:HumansAnimalsCells
    125. A combined approach for the localization and tandem affinity purification of protein complexes from metazoans. Sci STKE. 2005 Jan 11; 2005(266):pl1. Cheeseman IM, Desai A. PMID: 15644491.
      View in: PubMed   Mentions: 132     Fields:    Translation:HumansAnimalsCells
    126. Centriole assembly requires both centriolar and pericentriolar material proteins. Dev Cell. 2004 Dec; 7(6):815-29. Dammermann A, Müller-Reichert T, Pelletier L, Habermann B, Desai A, Oegema K. PMID: 15572125.
      View in: PubMed   Mentions: 128     Fields:    Translation:HumansAnimalsCells
    127. A conserved protein network controls assembly of the outer kinetochore and its ability to sustain tension. Genes Dev. 2004 Sep 15; 18(18):2255-68. Cheeseman IM, Niessen S, Anderson S, Hyndman F, Yates JR, Oegema K, Desai A. PMID: 15371340.
      View in: PubMed   Mentions: 206     Fields:    Translation:HumansAnimalsCells
    128. Cell division: feeling tense enough? Nature. 2004 Mar 04; 428(6978):32-3. Cheeseman IM, Desai A. PMID: 14999271.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    129. Cell division: AAAtacking the mitotic spindle. Curr Biol. 2004 Jan 20; 14(2):R70-2. Cheeseman IM, Desai A. PMID: 14738753.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    130. "Holo"er than thou: chromosome segregation and kinetochore function in C. elegans. Chromosome Res. 2004; 12(6):641-53. Maddox PS, Oegema K, Desai A, Cheeseman IM. PMID: 15289669.
      View in: PubMed   Mentions: 69     Fields:    Translation:AnimalsCells
    131. KNL-1 directs assembly of the microtubule-binding interface of the kinetochore in C. elegans. Genes Dev. 2003 Oct 01; 17(19):2421-35. Desai A, Rybina S, Müller-Reichert T, Shevchenko A, Shevchenko A, Hyman A, Oegema K. PMID: 14522947.
      View in: PubMed   Mentions: 114     Fields:    Translation:AnimalsCells
    132. The minus end in sight. Curr Biol. 2003 Aug 05; 13(15):R614-24. Dammermann A, Desai A, Oegema K. PMID: 12906817.
      View in: PubMed   Mentions: 51     Fields:    Translation:Cells
    133. The microtubule-destabilizing kinesin XKCM1 is required for chromosome positioning during spindle assembly. Curr Biol. 2002 Oct 29; 12(21):1885-9. Walczak CE, Gan EC, Desai A, Mitchison TJ, Kline-Smith SL. PMID: 12419191.
      View in: PubMed   Mentions: 35     Fields:    Translation:AnimalsCells
    134. Poleward microtubule flux is a major component of spindle dynamics and anaphase a in mitotic Drosophila embryos. Curr Biol. 2002 Oct 01; 12(19):1670-4. Maddox P, Desai A, Oegema K, Mitchison TJ, Salmon ED. PMID: 12361570.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    135. The (theoretical) yin and yang of spindle mechanics. Dev Cell. 2002 Oct; 3(4):465-7. Desai A. PMID: 12408797.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
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