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Rena Yadlapati

Title(s)Associate Professor Of Clinical, Medicine
SchoolHealth Sciences
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    Collapse Biography 
    Collapse Education and Training
    University of California Los Angeles, Los Angeles, CA06/2012Internal Medicine
    Northwestern University, Chicago, IL06/2016Gastroenterology & Hepatology
    Northwestern University, Chicago, IL06/2017Esophageal Physiology
    Northwestern University, Chicago, IL06/2017MS Health Services & Outcomes Research
    Collapse Awards and Honors
    2008Alpha Omega Alpha Honor Society
    2008Gold Humanism Honor Society
    2009  - 2010UCLA Commendation for Excellence in Medical Student Teaching
    2015Northwestern University - Excellence in Teaching
    2016ASGE Excellence in Diversity Research Award
    2016Northwestern University - Excellence in Mentorship Area of Scholarly Conentration Mentor
    2016Jameson Clinical Research Award - Northwestern
    2017  - 2019Clinical Faculty Scholars Program-University of Colorado

    Collapse Overview 
    Collapse Overview
    Dr. Yadlapati is director of Esophageal Diseases and Motility at UC San Diego Health and treats gastroesophageal reflux disease (GERD) and related conditions such as voice complaints (laryngopharyngeal reflux) and Barrett’s esophagus, swallowing disorders such as achalasia and esophageal motility disorders, and eosinophilic esophagitis.

    Dr. Yadlapati has expertise in interpreting esophageal manometry, Bravo testing, pH impedance and EndoFLIP. She performs upper GI endoscopies with dilation, ESO FLIP pneumatic dilation for achalasia, as well as colonoscopies.

    Dr. Yadlapati is an active clinical researcher with grant support. She is a co-author of national guidelines for esophageal disorders. The recipient of many teaching awards, Dr. Yadlapati has published over 60 articles in peer-reviewed publications. She speaks at the regional, national and international level on esophageal diseases.

    Dr. Yadlapati feels that each patient with esophageal complaints is unique, and that their care should be personalized using state-of-the-art technologies and team-based approaches to provide the highest quality of care.

    Collapse Research 
    Collapse Research Activities and Funding
    Determining Best Practices for Reflux Associated Laryngeal Symptoms
    American college of Gastroenterology Junior Faculty Development AwardJul 1, 2018 - Jun 30, 2020
    Role: Principal Investigator
    Effectiveness of Physiologic Testing in PPI Non-Responders
    NIH R01DK092217Apr 1, 2012 - Mar 31, 2022
    Role: Co-Investigator

    Collapse ORNG Applications 
    Collapse Websites
    Collapse Featured Presentations

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Yadlapati R, Gupta S, Pandolfino JE. Do Vigorous Esophageal Contractions Contribute to Rigorous Phenotyping of Gastroesophageal Reflux Disease? Dig Dis Sci. 2019 Jul 04. PMID: 31273596.
      View in: PubMed
    2. Keswani RN, Benson M, Beveridge C, Gawron AJ, Gluskin AB, Kahi CJ, Kaltenbach TR, McClure J, Schenck R, Yadlapati RH, Duloy A. Colonoscopy-Naïve Raters can be Trained to Assess Colonoscopy Quality. Clin Gastroenterol Hepatol. 2019 Jun 19. PMID: 31228569.
      View in: PubMed
    3. Agrawal N, Yadlapati R, Shabeeb N, Price CP, Lidder A, Shintani-Smith S, Bové M, Pandolfino J, Tan B. Relationship between extralaryngeal endoscopic findings, proton pump inhibitor (PPI) response, and pH measures in suspected laryngopharyngeal reflux. Dis Esophagus. 2019 Apr 01; 32(4). PMID: 30101358.
      View in: PubMed
    4. Yadlapati R, Ciolino JD, Craft J, Roman S, Pandolfino JE. Trajectory assessment is useful when day-to-day esophageal acid exposure varies in prolonged wireless pH monitoring. Dis Esophagus. 2019 Mar 01; 32(3). PMID: 30124795.
      View in: PubMed
    5. Yadlapati R, Furuta GT, Menard-Katcher P. New Developments in Esophageal Motility Testing. Curr Treat Options Gastroenterol. 2019 Mar; 17(1):76-88. PMID: 30712156.
      View in: PubMed
    6. Han S, Yadlapati R, Simon V, Ezekwe E, Early DS, Kushnir V, Hollander T, Brauer BC, Hammad H, Edmundowicz SA, Wood M, Shaheen NJ, Muthusamy RV, Komanduri S, Wani S. Dysplasia severity is associated with poor quality of life in patients with Barrett's esophagus referred for endoscopic eradication therapy. Dis Esophagus. 2019 Jan 01; 32(1). PMID: 30169612.
      View in: PubMed
    7. Schneider SL, Clary MS, Fink DS, Wang SX, Chowdhury FN, Yadlapati R, Jetté ME, Courey MS. Voice therapy associated with a decrease in the reflux symptoms index in patients with voice complaints. Laryngoscope. 2019 05; 129(5):1169-1173. PMID: 30444264.
      View in: PubMed
    8. Yadlapati R, DeLay K. Proton Pump Inhibitor-Refractory Gastroesophageal Reflux Disease. Med Clin North Am. 2019 Jan; 103(1):15-27. PMID: 30466671.
      View in: PubMed
    9. Machicado JD, Han S, Yadlapati RH, Simon VC, Qumseya BJ, Sultan S, Kushnir VM, Komanduri S, Rastogi A, Muthusamy VR, Haidry R, Ragunath K, Singh R, Hammad HT, Shaheen NJ, Wani S. A Survey of Expert Practice and Attitudes Regarding Advanced Imaging Modalities in Surveillance of Barrett's Esophagus. Dig Dis Sci. 2018 12; 63(12):3262-3271. PMID: 30178283.
      View in: PubMed
    10. Yadlapati R, Johnston ER, Gluskin AB, Gregory DL, Cyrus R, Werth L, Ciolino JD, Grande DP, Keswani RN. An Automated Inpatient Split-dose Bowel Preparation System Improves Colonoscopy Quality and Reduces Repeat Procedures. J Clin Gastroenterol. 2018 09; 52(8):709-714. PMID: 28727629.
      View in: PubMed
    11. Duloy A, Yadlapati RH, Benson M, Gawron AJ, Kahi CJ, Kaltenbach TR, McClure J, Gregory DL, Keswani RN. Video-Based Assessments of Colonoscopy Inspection Quality Correlate With Quality Metrics and Highlight Areas for Improvement. Clin Gastroenterol Hepatol. 2019 Mar; 17(4):691-700. PMID: 29908363.
      View in: PubMed
    12. Yadlapati R, Hungness ES, Pandolfino JE. Complications of Antireflux Surgery. Am J Gastroenterol. 2018 Aug; 113(8):1137-1147. PMID: 29899438.
      View in: PubMed
    13. Yadlapati R, Furuta GT, Wani S. The Ratio of SEP70 to Pepsin as a Biomarker of Laryngopharyngeal Reflux. Gastroenterology. 2018 07; 155(1):224-226. PMID: 29883572.
      View in: PubMed
    14. Alexeeva O, Keswani RN, Pandolfino JE, Liebovitz D, Gregory D, Yadlapati R. Electronic Clinical Decision Support Tools for Obesity and Gastroesophageal Reflux Disease: The Provider's Perspective. Am J Gastroenterol. 2018 Jun; 113(6):916. PMID: 29855547.
      View in: PubMed
    15. Yadlapati R, Vaezi MF, Vela MF, Spechler SJ, Shaheen NJ, Richter J, Lacy BE, Katzka D, Katz PO, Kahrilas PJ, Gyawali PC, Gerson L, Fass R, Castell DO, Craft J, Hillman L, Pandolfino JE. Management options for patients with GERD and persistent symptoms on proton pump inhibitors: recommendations from an expert panel. Am J Gastroenterol. 2018 Jul; 113(7):980-986. PMID: 29686276.
      View in: PubMed
    16. Yadlapati R, Craft J, Adkins CJ, Pandolfino JE. The Upper Esophageal Sphincter Assist Device Is Associated With Symptom Response in Reflux-Associated Laryngeal Symptoms. Clin Gastroenterol Hepatol. 2018 Oct; 16(10):1670-1672. PMID: 29408585.
      View in: PubMed
    17. Taft TH, Carlson DA, Triggs J, Craft J, Starkey K, Yadlapati R, Gregory D, Pandolfino JE. Evaluating the reliability and construct validity of the Eckardt symptom score as a measure of achalasia severity. Neurogastroenterol Motil. 2018 06; 30(6):e13287. PMID: 29315993.
      View in: PubMed
    18. Yadlapati R, Pandolfino JE, Alexeeva O, Gregory DL, Craven MR, Liebovitz D, Lichten A, Seger E, Workman M, St Peter N, Craft J, Doerfler B, Keswani RN. The Reflux Improvement and Monitoring (TRIM) Program Is Associated With Symptom Improvement and Weight Reduction for Patients With Obesity and Gastroesophageal Reflux Disease. Am J Gastroenterol. 2018 01; 113(1):23-30. PMID: 29016559.
      View in: PubMed
    19. Kahrilas P, Yadlapati R, Roman S. Emerging dilemmas in the diagnosis and management of gastroesophageal reflux disease. F1000Res. 2017; 6:1748. PMID: 29034088.
      View in: PubMed
    20. Yadlapati R, Tye M, Keefer L, Kahrilas PJ, Pandolfino JE. Psychosocial Distress and Quality of Life Impairment Are Associated With Symptom Severity in PPI Non-Responders With Normal Impedance-pH Profiles. Am J Gastroenterol. 2018 01; 113(1):31-38. PMID: 28895583.
      View in: PubMed
    21. Yadlapati R, Tye M, Roman S, Kahrilas PJ, Ritter K, Pandolfino JE. Postprandial High-Resolution Impedance Manometry Identifies Mechanisms of Nonresponse to Proton Pump Inhibitors. Clin Gastroenterol Hepatol. 2018 02; 16(2):211-218.e1. PMID: 28911949.
      View in: PubMed
    22. Hillman L, Yadlapati R, Whitsett M, Thuluvath AJ, Berendsen MA, Pandolfino JE. Review of antireflux procedures for proton pump inhibitor nonresponsive gastroesophageal reflux disease. Dis Esophagus. 2017 Sep 01; 30(9):1-14. PMID: 28859357.
      View in: PubMed
    23. Hillman L, Yadlapati R, Thuluvath AJ, Berendsen MA, Pandolfino JE. A review of medical therapy for proton pump inhibitor nonresponsive gastroesophageal reflux disease. Dis Esophagus. 2017 Sep 01; 30(9):1-15. PMID: 28859358.
      View in: PubMed
    24. Yadlapati R, Kahrilas PJ. The "dangers" of chronic proton pump inhibitor use. J Allergy Clin Immunol. 2018 01; 141(1):79-81. PMID: 28729001.
      View in: PubMed
    25. Siegel A, Boike J, Trivedi I, Yadlapati R. Posttransplant Lymphoproliferative Disorder of the Small Bowel as an Unexpected Cause of Iron Deficiency Anemia Decades after Heart Transplantation. ACG Case Rep J. 2017; 4:e86. PMID: 28706962.
      View in: PubMed
    26. Yadlapati R. High-resolution esophageal manometry: interpretation in clinical practice. Curr Opin Gastroenterol. 2017 Jul; 33(4):301-309. PMID: 28426462.
      View in: PubMed
    27. Wani S, Muthusamy VR, Shaheen NJ, Yadlapati R, Wilson R, Abrams JA, Bergman J, Chak A, Chang K, Das A, Dumot J, Edmundowicz SA, Eisen G, Falk GW, Fennerty MB, Gerson L, Ginsberg GG, Grande D, Hall M, Harnke B, Inadomi J, Jankowski J, Lightdale CJ, Makker J, Odze RD, Pech O, Sampliner RE, Spechler S, Triadafilopoulos G, Wallace MB, Wang K, Waxman I, Komanduri S. Development of Quality Indicators for Endoscopic Eradication Therapies in Barrett's Esophagus: The TREAT-BE (Treatment With Resection and Endoscopic Ablation Techniques for Barrett's Esophagus) Consortium. Am J Gastroenterol. 2017 07; 112(7):1032-1048. PMID: 28570552.
      View in: PubMed
    28. Wani S, Muthusamy VR, Shaheen NJ, Yadlapati R, Wilson R, Abrams JA, Bergman J, Chak A, Chang K, Das A, Dumot J, Edmundowicz SA, Eisen G, Falk GW, Fennerty MB, Gerson L, Ginsberg GG, Grande D, Hall M, Harnke B, Inadomi J, Jankowski J, Lightdale CJ, Makker J, Odze RD, Pech O, Sampliner RE, Spechler S, Triadafilopoulos G, Wallace MB, Wang K, Waxman I, Komanduri S. Development of quality indicators for endoscopic eradication therapies in Barrett's esophagus: the TREAT-BE (Treatment with Resection and Endoscopic Ablation Techniques for Barrett's Esophagus) Consortium. Gastrointest Endosc. 2017 07; 86(1):1-17.e3. PMID: 28576294.
      View in: PubMed
    29. Gyawali CP, Roman S, Bredenoord AJ, Fox M, Keller J, Pandolfino JE, Sifrim D, Tatum R, Yadlapati R, Savarino E. Classification of esophageal motor findings in gastro-esophageal reflux disease: Conclusions from an international consensus group. Neurogastroenterol Motil. 2017 Dec; 29(12). PMID: 28544357.
      View in: PubMed
    30. Yadlapati R, Pandolfino JE, Tan BK. Response to Song et al. Am J Gastroenterol. 2017 05; 112(5):812-813. PMID: 28469219.
      View in: PubMed
    31. Roman S, Gyawali CP, Savarino E, Yadlapati R, Zerbib F, Wu J, Vela M, Tutuian R, Tatum R, Sifrim D, Keller J, Fox M, Pandolfino JE, Bredenoord AJ. Ambulatory reflux monitoring for diagnosis of gastro-esophageal reflux disease: Update of the Porto consensus and recommendations from an international consensus group. Neurogastroenterol Motil. 2017 Oct; 29(10):1-15. PMID: 28370768.
      View in: PubMed
    32. Yadlapati R. High Resolution Manometry Vs Conventional Line Tracing for Esophageal Motility Disorders. Gastroenterol Hepatol (N Y). 2017 Mar; 13(3):176-178. PMID: 28539845.
      View in: PubMed
    33. Yadlapati R, Kahrilas PJ. When is proton pump inhibitor use appropriate? BMC Med. 2017 02 21; 15(1):36. PMID: 28219434.
      View in: PubMed
    34. Yadlapati R, Dakhoul L, Pandolfino JE, Keswani RN. The Quality of Care for Gastroesophageal Reflux Disease. Dig Dis Sci. 2017 03; 62(3):569-576. PMID: 28028689.
      View in: PubMed
    35. Yadlapati R, Keswani RN, Dunbar KB, Gawron AJ, Gyawali CP, Kahrilas PJ, Katz PO, Katzka D, Spechler SJ, Tatum R, Pandolfino JE. Benchmarks for the interpretation of esophageal high-resolution manometry. Neurogastroenterol Motil. 2017 Apr; 29(4). PMID: 27739183.
      View in: PubMed
    36. Yadlapati R, Keswani RN, Ciolino JD, Grande DP, Listernick ZI, Carlson DA, Castell DO, Dunbar KB, Gawron AJ, Gyawali CP, Katz PO, Katzka D, Lacy BE, Spechler SJ, Tatum R, Vela MF, Pandolfino JE. A System to Assess the Competency for Interpretation of Esophageal Manometry Identifies Variation in Learning Curves. Clin Gastroenterol Hepatol. 2017 Nov; 15(11):1708-1714.e3. PMID: 27473627.
      View in: PubMed
    37. Yadlapati R, Pandolfino JE, Lidder AK, Shabeeb N, Jaiyeola DM, Adkins C, Agrawal N, Cooper A, Price CP, Ciolino JD, Gawron AJ, Smith SS, Bove M, Tan BK. Oropharyngeal pH Testing Does Not Predict Response to Proton Pump Inhibitor Therapy in Patients with Laryngeal Symptoms. Am J Gastroenterol. 2016 Nov; 111(11):1517-1524. PMID: 27091320.
      View in: PubMed
    38. Yadlapati R. Publishing as a Fellow: Why & How. ACG Case Rep J. 2016 Apr; 3(3):146-7. PMID: 27144184.
      View in: PubMed
    39. Yadlapati R, Keswani RN, Pandolfino JE. Competency based medical education in gastrointestinal motility. Neurogastroenterol Motil. 2016 Oct; 28(10):1460-4. PMID: 27061311.
      View in: PubMed
    40. Yadlapati R, Pandolfino JE. Novel Tools, Biomarkers, and Disease Entities in Esophageal Disorders. Clin Transl Gastroenterol. 2016 Feb 11; 7:e144. PMID: 26866393.
      View in: PubMed
    41. Yadlapati R, Adkins C, Jaiyeola DM, Lidder AK, Gawron AJ, Tan BK, Shabeeb N, Price CP, Agrawal N, Ellenbogen M, Smith SS, Bove M, Pandolfino JE. Abilities of Oropharyngeal pH Tests and Salivary Pepsin Analysis to Discriminate Between Asymptomatic Volunteers and Subjects With Symptoms of Laryngeal Irritation. Clin Gastroenterol Hepatol. 2016 Apr; 14(4):535-542.e2. PMID: 26689899.
      View in: PubMed
    42. Yadlapati R, Gawron AJ, Keswani RN, Bilimoria K, Castell DO, Dunbar KB, Gyawali CP, Jobe BA, Katz PO, Katzka DA, Lacy BE, Massey BT, Richter JE, Schnoll-Sussman F, Spechler SJ, Tatum R, Vela MF, Pandolfino JE. Identification of Quality Measures for Performance of and Interpretation of Data From Esophageal Manometry. Clin Gastroenterol Hepatol. 2016 Apr; 14(4):526-534.e1. PMID: 26499925.
      View in: PubMed
    43. Yadlapati R. Finding the Right "Balance" for the Trainee. ACG Case Rep J. 2015 Oct; 3(1):1-2. PMID: 26504860.
      View in: PubMed
    44. Yadlapati R, Johnston ER, Gregory DL, Ciolino JD, Cooper A, Keswani RN. Predictors of Inadequate Inpatient Colonoscopy Preparation and Its Association with Hospital Length of Stay and Costs. Dig Dis Sci. 2015 Nov; 60(11):3482-90. PMID: 26093612.
      View in: PubMed
    45. Carlson DA, Ravi K, Kahrilas PJ, Gyawali CP, Bredenoord AJ, Castell DO, Spechler SJ, Halland M, Kanuri N, Katzka DA, Leggett CL, Roman S, Saenz JB, Sayuk GS, Wong AC, Yadlapati R, Ciolino JD, Fox MR, Pandolfino JE. Diagnosis of Esophageal Motility Disorders: Esophageal Pressure Topography vs. Conventional Line Tracing. Am J Gastroenterol. 2015 Jul; 110(7):967-77; quiz 978. PMID: 26032151.
      View in: PubMed
    46. Keswani RN, Yadlapati R, Gleason KM, Ciolino JD, Manka M, O'Leary KJ, Barnard C, Pandolfino JE. Physician report cards and implementing standards of practice are both significantly associated with improved screening colonoscopy quality. Am J Gastroenterol. 2015 Aug; 110(8):1134-9. PMID: 25869388.
      View in: PubMed
    47. Yadlapati R, Gawron AJ, Bilimoria K, Keswani RN, Dunbar KB, Kahrilas PJ, Katz P, Richter J, Schnoll-Sussman F, Soper N, Vela MF, Pandolfino JE. Development of quality measures for the care of patients with gastroesophageal reflux disease. Clin Gastroenterol Hepatol. 2015 May; 13(5):874-83.e2. PMID: 25460560.
      View in: PubMed
    48. Yadlapati R, Law R, Komanduri S. Gallbladder halo sign: emphysematous cholecystitis caused by cystic duct obstruction. Clin Gastroenterol Hepatol. 2015 Mar; 13(3):A27-8. PMID: 25445766.
      View in: PubMed
    49. Yadlapati R, Gawron A, Keswani RN. Patient satisfaction does not correlate with established colonoscopy quality metrics. Am J Gastroenterol. 2014 Jul; 109(7):1089-91. PMID: 24989104.
      View in: PubMed
    50. Gawron AJ, Yadlapati R. Disparities in endoscopy use for colorectal cancer screening in the United States. Dig Dis Sci. 2014 Mar; 59(3):530-7. PMID: 24248417.
      View in: PubMed