Lorraine Pillus

Title(s)Professor, Molecular Biology
SchoolVc-academic Affairs
Address9500 Gilman Drive #
La Jolla CA 92093
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    Collapse Research 
    Collapse Research Activities and Funding
    Network-Driven Dynamics of Replicative Aging
    NIH R01AG056440Aug 1, 2017 - May 31, 2022
    Role: Co-Principal Investigator
    Massively parallel epigenomics: building new value with current resources
    NIH R21HG005252Feb 1, 2010 - Jan 31, 2013
    Role: Principal Investigator
    Chromatin Regulation by Deacetylation and SUMO-Targeted Ubiquitin Ligation
    NIH R01GM090177Jul 1, 2009 - Jun 30, 2013
    Role: Principal Investigator
    Functional Analysis of the SIR2/HST Deacetylases
    NIH/NIGMS R01GM054778Aug 1, 1997 - Sep 14, 1998
    Role: Principal Investigator
    Analysis of MYST Family Acetyltransferase Functions
    NIH/NIGMS R01GM056469Aug 1, 1997 - Sep 14, 1998
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    1. Non-canonical chromatin-based functions for the threonine metabolic pathway. Sci Rep. 2024 09 30; 14(1):22629. Chik JK, Su XB, Klepin S, Raygoza J, Pillus L. PMID: 39349514; PMCID: PMC11442984.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    2. Engineering longevity-design of a synthetic gene oscillator to slow cellular aging. Science. 2023 04 28; 380(6643):376-381. Zhou Z, Liu Y, Feng Y, Klepin S, Tsimring LS, Pillus L, Hasty J, Hao N. PMID: 37104589; PMCID: PMC10249776.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    3. Functional tug of war between kinases, phosphatases, and the Gcn5 acetyltransferase in chromatin and cell cycle checkpoint controls. G3 (Bethesda). 2023 04 11; 13(4). Liu Q, Pillus L, Petty EL. PMID: 36772957; PMCID: PMC10085806.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    4. Age-dependent aggregation of ribosomal RNA-binding proteins links deterioration in chromatin stability with challenges to proteostasis. Elife. 2022 Oct 04; 11. Paxman J, Zhou Z, O'Laughlin R, Liu Y, Li Y, Tian W, Su H, Jiang Y, Holness SE, Stasiowski E, Tsimring LS, Pillus L, Hasty J, Hao N. PMID: 36194205; PMCID: PMC9578700.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    5. Cell cycle roles for GCN5 revealed through genetic suppression. Biochim Biophys Acta Gene Regul Mech. 2021 02; 1864(2):194625. Petty EL, Pillus L. PMID: 32798737.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    6. A programmable fate decision landscape underlies single-cell aging in yeast. Science. 2020 Jul 17; 369(6501):325-329. Li Y, Jiang Y, Paxman J, O'Laughlin R, Klepin S, Zhu Y, Pillus L, Tsimring LS, Hasty J, Hao N. PMID: 32675375; PMCID: PMC7437498.
      View in: PubMed   Mentions: 48     Fields:    Translation:AnimalsCells
    7. Advances in quantitative biology methods for studying replicative aging in Saccharomyces cerevisiae. Transl Med Aging. 2020; 4:151-160. O'Laughlin R, Jin M, Li Y, Pillus L, Tsimring LS, Hasty J, Hao N. PMID: 33880425; PMCID: PMC8054985.
      View in: PubMed   Mentions: 12  
    8. Divergent Aging of Isogenic Yeast Cells Revealed through Single-Cell Phenotypic Dynamics. Cell Syst. 2019 03 27; 8(3):242-253.e3. Jin M, Li Y, O'Laughlin R, Bittihn P, Pillus L, Tsimring LS, Hasty J, Hao N. PMID: 30852250; PMCID: PMC6514117.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    9. Connecting GCN5's centromeric SAGA to the mitotic tension-sensing checkpoint. Mol Biol Cell. 2018 09 01; 29(18):2201-2212. Petty EL, Evpak M, Pillus L. PMID: 29995571; PMCID: PMC6249797.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    10. Multigenerational silencing dynamics control cell aging. Proc Natl Acad Sci U S A. 2017 10 17; 114(42):11253-11258. Li Y, Jin M, O'Laughlin R, Bittihn P, Tsimring LS, Pillus L, Hasty J, Hao N. PMID: 29073021; PMCID: PMC5651738.
      View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
    11. Critical genomic regulation mediated by Enhancer of Polycomb. Curr Genet. 2018 Feb; 64(1):147-154. Searle NE, Pillus L. PMID: 28884217; PMCID: PMC6287951.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    12. Phosphorylation of the 19S regulatory particle ATPase subunit, Rpt6, modifies susceptibility to proteotoxic stress and protein aggregation. PLoS One. 2017; 12(6):e0179893. Marquez-Lona EM, Torres-Machorro AL, Gonzales FR, Pillus L, Patrick GN. PMID: 28662109; PMCID: PMC5491056.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    13. The replicative lifespan-extending deletion of SGF73 results in altered ribosomal gene expression in yeast. Aging Cell. 2017 08; 16(4):785-796. Mason AG, Garza RM, McCormick MA, Patel B, Kennedy BK, Pillus L, La Spada AR. PMID: 28568901; PMCID: PMC5506417.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    14. Chromatin Regulation by the NuA4 Acetyltransferase Complex Is Mediated by Essential Interactions Between Enhancer of Polycomb (Epl1) and Esa1. Genetics. 2017 03; 205(3):1125-1137. Searle NE, Torres-Machorro AL, Pillus L. PMID: 28108589; PMCID: PMC5340328.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    15. Promotion of Cell Viability and Histone Gene Expression by the Acetyltransferase Gcn5 and the Protein Phosphatase PP2A in Saccharomyces cerevisiae. Genetics. 2016 08; 203(4):1693-707. Petty EL, Lafon A, Tomlinson SL, Mendelsohn BA, Pillus L. PMID: 27317677; PMCID: PMC4981271.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    16. Functions for diverse metabolic activities in heterochromatin. Proc Natl Acad Sci U S A. 2016 Mar 15; 113(11):E1526-35. Su XB, Pillus L. PMID: 26936955; PMCID: PMC4801238.
      View in: PubMed   Mentions: 9     Fields:    Translation:Cells
    17. The Set3 Complex Antagonizes the MYST Acetyltransferase Esa1 in the DNA Damage Response. Mol Cell Biol. 2015 Nov; 35(21):3714-25. Torres-Machorro AL, Clark LG, Chang CS, Pillus L. PMID: 26303527; PMCID: PMC4589593.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    18. A moonlighting metabolic protein influences repair at DNA double-stranded breaks. Nucleic Acids Res. 2015 Feb 18; 43(3):1646-58. Torres-Machorro AL, Aris JP, Pillus L. PMID: 25628362; PMCID: PMC4330366.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    19. Tyrosine phosphorylation of histone H2A by CK2 regulates transcriptional elongation. Nature. 2014 Dec 11; 516(7530):267-71. Basnet H, Su XB, Tan Y, Meisenhelder J, Merkurjev D, Ohgi KA, Hunter T, Pillus L, Rosenfeld MG. PMID: 25252977; PMCID: PMC4461219.
      View in: PubMed   Mentions: 66     Fields:    Translation:HumansAnimalsCells
    20. The SAGA histone deubiquitinase module controls yeast replicative lifespan via Sir2 interaction. Cell Rep. 2014 Jul 24; 8(2):477-86. McCormick MA, Mason AG, Guyenet SJ, Dang W, Garza RM, Ting MK, Moller RM, Berger SL, Kaeberlein M, Pillus L, La Spada AR, Kennedy BK. PMID: 25043177; PMCID: PMC4284099.
      View in: PubMed   Mentions: 37     Fields:    Translation:AnimalsCells
    21. Bypassing the requirement for an essential MYST acetyltransferase. Genetics. 2014 Jul; 197(3):851-63. Torres-Machorro AL, Pillus L. PMID: 24831819; PMCID: PMC4096366.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    22. Unexpected function of the glucanosyltransferase Gas1 in the DNA damage response linked to histone H3 acetyltransferases in Saccharomyces cerevisiae. Genetics. 2014 Apr; 196(4):1029-39. Eustice M, Pillus L. PMID: 24532730; PMCID: PMC3982697.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    23. Balancing chromatin remodeling and histone modifications in transcription. Trends Genet. 2013 Nov; 29(11):621-9. Petty E, Pillus L. PMID: 23870137; PMCID: PMC4408995.
      View in: PubMed   Mentions: 53     Fields:    Translation:AnimalsCells
    24. STUbLs in chromatin and genome stability. Biopolymers. 2013 Feb; 99(2):146-54. Garza R, Pillus L. PMID: 23175389; PMCID: PMC3507437.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    25. Decoupling epigenetic and genetic effects through systematic analysis of gene position. Cell Rep. 2013 Jan 31; 3(1):128-37. Chen M, Licon K, Otsuka R, Pillus L, Ideker T. PMID: 23291096; PMCID: PMC3563736.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    26. Functional antagonism between Sas3 and Gcn5 acetyltransferases and ISWI chromatin remodelers. PLoS Genet. 2012; 8(10):e1002994. Lafon A, Petty E, Pillus L. PMID: 23055944; PMCID: PMC3464200.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    27. Suppression analysis of esa1 mutants in Saccharomyces cerevisiae links NAB3 to transcriptional silencing and nucleolar functions. G3 (Bethesda). 2012 Oct; 2(10):1223-32. Chang CS, Clarke A, Pillus L. PMID: 23050233; PMCID: PMC3464115.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    28. Homocitrate synthase connects amino acid metabolism to chromatin functions through Esa1 and DNA damage. Genes Dev. 2010 Sep 01; 24(17):1903-13. Scott EM, Pillus L. PMID: 20810648; PMCID: PMC2932972.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    29. Structural basis for L-lysine feedback inhibition of homocitrate synthase. J Biol Chem. 2010 Apr 02; 285(14):10446-53. Bulfer SL, Scott EM, Pillus L, Trievel RC. PMID: 20089861; PMCID: PMC2856251.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    30. Crystal structure and functional analysis of homocitrate synthase, an essential enzyme in lysine biosynthesis. J Biol Chem. 2009 Dec 18; 284(51):35769-80. Bulfer SL, Scott EM, Couture JF, Pillus L, Trievel RC. PMID: 19776021; PMCID: PMC2791007.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    31. The SAGA subunit Ada2 functions in transcriptional silencing. Mol Cell Biol. 2009 Nov; 29(22):6033-45. Jacobson S, Pillus L. PMID: 19737915; PMCID: PMC2772568.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    32. Collaboration between the essential Esa1 acetyltransferase and the Rpd3 deacetylase is mediated by H4K12 histone acetylation in Saccharomyces cerevisiae. Genetics. 2009 Sep; 183(1):149-60. Chang CS, Pillus L. PMID: 19596907; PMCID: PMC2746140.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    33. The glucanosyltransferase Gas1 functions in transcriptional silencing. Proc Natl Acad Sci U S A. 2009 Jul 07; 106(27):11224-9. Koch MR, Pillus L. PMID: 19541632; PMCID: PMC2708717.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    34. Dynamic reprogramming of transcription factors to and from the subtelomere. Genome Res. 2009 Jun; 19(6):1014-25. Mak HC, Pillus L, Ideker T. PMID: 19372386; PMCID: PMC2694488.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    35. Identifying critical non-catalytic residues that modulate protein kinase A activity. PLoS One. 2009; 4(3):e4746. Kennedy EJ, Yang J, Pillus L, Taylor SS, Ghosh G. PMID: 19270744; PMCID: PMC2650257.
      View in: PubMed   Mentions: 11     Fields:    Translation:Animals
    36. MYSTs mark chromatin for chromosomal functions. Curr Opin Cell Biol. 2008 Jun; 20(3):326-33. Pillus L. PMID: 18511253; PMCID: PMC2717219.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    37. Slx5 promotes transcriptional silencing and is required for robust growth in the absence of Sir2. Mol Cell Biol. 2008 Feb; 28(4):1361-72. Darst RP, Garcia SN, Koch MR, Pillus L. PMID: 18086879; PMCID: PMC2258744.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    38. New nomenclature for chromatin-modifying enzymes. Cell. 2007 Nov 16; 131(4):633-6. Allis CD, Berger SL, Cote J, Dent S, Jenuwien T, Kouzarides T, Pillus L, Reinberg D, Shi Y, Shiekhattar R, Shilatifard A, Workman J, Zhang Y. PMID: 18022353.
      View in: PubMed   Mentions: 441     Fields:    Translation:HumansAnimalsCells
    39. Identification of functionally distinct regions that mediate biological activity of the protein kinase a homolog Tpk2. J Biol Chem. 2008 Jan 11; 283(2):1084-93. Kennedy EJ, Ghosh G, Pillus L. PMID: 17971450.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    40. MYST opportunities for growth control: yeast genes illuminate human cancer gene functions. Oncogene. 2007 Aug 13; 26(37):5373-84. Lafon A, Chang CS, Scott EM, Jacobson SJ, Pillus L. PMID: 17694079.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansAnimalsCells
    41. Nuclear export modulates the cytoplasmic Sir2 homologue Hst2. EMBO Rep. 2006 Dec; 7(12):1247-51. Wilson JM, Le VQ, Zimmerman C, Marmorstein R, Pillus L. PMID: 17110954; PMCID: PMC1794688.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    42. Chromatin-modifiying enzymes are essential when the Saccharomyces cerevisiae morphogenesis checkpoint is constitutively activated. Genetics. 2006 Nov; 174(3):1135-49. Ruault M, Pillus L. PMID: 16951088; PMCID: PMC1667082.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    43. Distinct roles for the essential MYST family HAT Esa1p in transcriptional silencing. Mol Biol Cell. 2006 Apr; 17(4):1744-57. Clarke AS, Samal E, Pillus L. PMID: 16436512; PMCID: PMC1415314.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
    44. Pho5p and newly identified nucleotide pyrophosphatases/ phosphodiesterases regulate extracellular nucleotide phosphate metabolism in Saccharomyces cerevisiae. Eukaryot Cell. 2005 Nov; 4(11):1892-901. Kennedy EJ, Pillus L, Ghosh G. PMID: 16278456; PMCID: PMC1287867.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    45. Genomewide analysis of nucleosome density histone acetylation and HDAC function in fission yeast. EMBO J. 2005 Aug 17; 24(16):2906-18. Wirén M, Silverstein RA, Sinha I, Walfridsson J, Lee HM, Laurenson P, Pillus L, Robyr D, Grunstein M, Ekwall K. PMID: 16079916; PMCID: PMC1187943.
      View in: PubMed   Mentions: 77     Fields:    Translation:AnimalsCells
    46. Histone H3 phosphorylation can promote TBP recruitment through distinct promoter-specific mechanisms. EMBO J. 2005 Mar 09; 24(5):997-1008. Lo WS, Gamache ER, Henry KW, Yang D, Pillus L, Berger SL. PMID: 15719021; PMCID: PMC554127.
      View in: PubMed   Mentions: 46     Fields:    Translation:AnimalsCells
    47. Conserved locus-specific silencing functions of Schizosaccharomyces pombe sir2+. Genetics. 2005 Mar; 169(3):1243-60. Freeman-Cook LL, Gómez EB, Spedale EJ, Marlett J, Forsburg SL, Pillus L, Laurenson P. PMID: 15545655; PMCID: PMC1449530.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
    48. Molecular requirements for gene expression mediated by targeted histone acetyltransferases. Mol Cell Biol. 2004 Jul; 24(13):6029-39. Jacobson S, Pillus L. PMID: 15199156; PMCID: PMC480887.
      View in: PubMed   Mentions: 10     Fields:    Translation:Cells
    49. Functional analyses of chromatin modifications in yeast. Methods Enzymol. 2004; 377:3-55. Jacobson SJ, Laurenson PM, Pillus L. PMID: 14979016.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    50. SIR1 and the origin of epigenetic states in Saccharomyces cerevisiae. Cold Spring Harb Symp Quant Biol. 2004; 69:259-65. Pillus L, Rine J. PMID: 16117657.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    51. The Sir4 C-terminal coiled coil is required for telomeric and mating type silencing in Saccharomyces cerevisiae. J Mol Biol. 2003 Dec 05; 334(4):769-80. Murphy GA, Spedale EJ, Powell ST, Pillus L, Schultz SC, Chen L. PMID: 14636601.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    52. Transcriptional activation via sequential histone H2B ubiquitylation and deubiquitylation, mediated by SAGA-associated Ubp8. Genes Dev. 2003 Nov 01; 17(21):2648-63. Henry KW, Wyce A, Lo WS, Duggan LJ, Emre NC, Kao CF, Pillus L, Shilatifard A, Osley MA, Berger SL. PMID: 14563679; PMCID: PMC280615.
      View in: PubMed   Mentions: 341     Fields:    Translation:AnimalsCells
    53. Structural basis for histone and phosphohistone binding by the GCN5 histone acetyltransferase. Mol Cell. 2003 Aug; 12(2):461-73. Clements A, Poux AN, Lo WS, Pillus L, Berger SL, Marmorstein R. PMID: 14536085.
      View in: PubMed   Mentions: 60     Fields:    Translation:AnimalsCells
    54. Telomerase-independent proliferation is influenced by cell type in Saccharomyces cerevisiae. Genetics. 2003 Jul; 164(3):909-21. Lowell JE, Roughton AI, Lundblad V, Pillus L. PMID: 12871903; PMCID: PMC1462614.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    55. Histone deacetylation by Sir2 generates a transcriptionally repressed nucleoprotein complex. Proc Natl Acad Sci U S A. 2003 Feb 18; 100(4):1609-14. Parsons XH, Garcia SN, Pillus L, Kadonaga JT. PMID: 12571358; PMCID: PMC149880.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    56. A unique class of conditional sir2 mutants displays distinct silencing defects in Saccharomyces cerevisiae. Genetics. 2002 Oct; 162(2):721-36. Garcia SN, Pillus L. PMID: 12399383; PMCID: PMC1462279.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    57. Histone H3 specific acetyltransferases are essential for cell cycle progression. Genes Dev. 2001 Dec 01; 15(23):3144-54. Howe L, Auston D, Grant P, John S, Cook RG, Workman JL, Pillus L. PMID: 11731478; PMCID: PMC312843.
      View in: PubMed   Mentions: 110     Fields:    Translation:AnimalsCells
    58. Deciphering NAD-dependent deacetylases. Cell. 2001 Apr 20; 105(2):161-4. Dutnall RN, Pillus L. PMID: 11336664.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    59. Two classes of sir3 mutants enhance the sir1 mutant mating defect and abolish telomeric silencing in Saccharomyces cerevisiae. Genetics. 2000 Jun; 155(2):509-22. Stone EM, Reifsnyder C, McVey M, Gazo B, Pillus L. PMID: 10835377; PMCID: PMC1461112.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    60. The silencing protein SIR2 and its homologs are NAD-dependent protein deacetylases. Proc Natl Acad Sci U S A. 2000 May 23; 97(11):5807-11. Landry J, Sutton A, Tafrov ST, Heller RC, Stebbins J, Pillus L, Sternglanz R. PMID: 10811920; PMCID: PMC18515.
      View in: PubMed   Mentions: 402     Fields:    Translation:AnimalsCells
    61. MAP kinase signaling induces nuclear reorganization in budding yeast. Curr Biol. 2000 Apr 06; 10(7):373-82. Stone EM, Heun P, Laroche T, Pillus L, Gasser SM. PMID: 10753745.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    62. The Schizosaccharomyces pombe hst4(+) gene is a SIR2 homologue with silencing and centromeric functions. Mol Biol Cell. 1999 Oct; 10(10):3171-86. Freeman-Cook LL, Sherman JM, Brachmann CB, Allshire RC, Boeke JD, Pillus L. PMID: 10512858; PMCID: PMC25575.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    63. NuA4, an essential transcription adaptor/histone H4 acetyltransferase complex containing Esa1p and the ATM-related cofactor Tra1p. EMBO J. 1999 Sep 15; 18(18):5108-19. Allard S, Utley RT, Savard J, Clarke A, Grant P, Brandl CJ, Pillus L, Workman JL, Côté J. PMID: 10487762; PMCID: PMC1171581.
      View in: PubMed   Mentions: 223     Fields:    Translation:HumansAnimalsCells
    64. The conserved core of a human SIR2 homologue functions in yeast silencing. Mol Biol Cell. 1999 Sep; 10(9):3045-59. Sherman JM, Stone EM, Freeman-Cook LL, Brachmann CB, Boeke JD, Pillus L. PMID: 10473645; PMCID: PMC25551.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansAnimalsCells
    65. Net results of nucleolar dynamics. Cell. 1999 Jun 25; 97(7):825-8. Garcia SN, Pillus L. PMID: 10399910.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    66. Modifying chromatin and concepts of cancer. Curr Opin Genet Dev. 1999 Apr; 9(2):175-84. Jacobson S, Pillus L. PMID: 10322138.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    67. Esa1p is an essential histone acetyltransferase required for cell cycle progression. Mol Cell Biol. 1999 Apr; 19(4):2515-26. Clarke AS, Lowell JE, Jacobson SJ, Pillus L. PMID: 10082517; PMCID: PMC84044.
      View in: PubMed   Mentions: 180     Fields:    Translation:AnimalsCells
    68. Distribution of a limited Sir2 protein pool regulates the strength of yeast rDNA silencing and is modulated by Sir4p. Genetics. 1998 Jul; 149(3):1205-19. Smith JS, Brachmann CB, Pillus L, Boeke JD. PMID: 9649515; PMCID: PMC1460222.
      View in: PubMed   Mentions: 75     Fields:    Translation:AnimalsCells
    69. Silent chromatin in yeast: an orchestrated medley featuring Sir3p [corrected]. Bioessays. 1998 Jan; 20(1):30-40. Stone EM, Pillus L. PMID: 9504045.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    70. Telomere tales: chromatin, telomerase and telomere function in Saccharomyces cerevisiae. Cell Mol Life Sci. 1998 Jan; 54(1):32-49. Lowell JE, Pillus L. PMID: 9487385; PMCID: PMC11147197.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    71. SET1, a yeast member of the trithorax family, functions in transcriptional silencing and diverse cellular processes. Mol Biol Cell. 1997 Dec; 8(12):2421-36. Nislow C, Ray E, Pillus L. PMID: 9398665; PMCID: PMC25717.
      View in: PubMed   Mentions: 126     Fields:    Translation:HumansAnimalsCells
    72. An uncertain silence. Trends Genet. 1997 Aug; 13(8):308-13. Sherman JM, Pillus L. PMID: 9260516.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    73. Mammalian homologues of the Polycomb-group gene Enhancer of zeste mediate gene silencing in Drosophila heterochromatin and at S. cerevisiae telomeres. EMBO J. 1997 Jun 02; 16(11):3219-32. Laible G, Wolf A, Dorn R, Reuter G, Nislow C, Lebersorger A, Popkin D, Pillus L, Jenuwein T. PMID: 9214638; PMCID: PMC1169939.
      View in: PubMed   Mentions: 120     Fields:    Translation:HumansAnimalsCells
    74. Yeast SAS silencing genes and human genes associated with AML and HIV-1 Tat interactions are homologous with acetyltransferases. Nat Genet. 1997 May; 16(1):109. Reifnyder C, Lowell J, Clarke A, Pillus L. PMID: 9140406.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    75. Activation of an MAP kinase cascade leads to Sir3p hyperphosphorylation and strengthens transcriptional silencing. J Cell Biol. 1996 Nov; 135(3):571-83. Stone EM, Pillus L. PMID: 8909534; PMCID: PMC2121063.
      View in: PubMed   Mentions: 38     Fields:    Translation:AnimalsCells
    76. Yeast SAS silencing genes and human genes associated with AML and HIV-1 Tat interactions are homologous with acetyltransferases. Nat Genet. 1996 Sep; 14(1):42-9. Reifsnyder C, Lowell J, Clarke A, Pillus L. PMID: 8782818.
      View in: PubMed   Mentions: 102     Fields:    Translation:HumansAnimalsCells
    77. The SIR2 gene family, conserved from bacteria to humans, functions in silencing, cell cycle progression, and chromosome stability. Genes Dev. 1995 Dec 01; 9(23):2888-902. Brachmann CB, Sherman JM, Devine SE, Cameron EE, Pillus L, Boeke JD. PMID: 7498786.
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