Lorraine Pillus

Title(s)Professor, Molecular Biology
SchoolVc-academic Affairs
Address9500 Gilman Drive #
La Jolla CA 92093
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    Collapse Research 
    Collapse Research Activities and Funding
    Network-Driven Dynamics of Replicative Aging
    NIH R01AG056440Aug 1, 2017 - May 31, 2022
    Role: Co-Principal Investigator
    Massively parallel epigenomics: building new value with current resources
    NIH R21HG005252Feb 1, 2010 - Jan 31, 2013
    Role: Principal Investigator
    Chromatin Regulation by Deacetylation and SUMO-Targeted Ubiquitin Ligation
    NIH R01GM090177Jul 1, 2009 - Jun 30, 2013
    Role: Principal Investigator
    Functional Analysis of the SIR2/HST Deacetylases
    NIH/NIGMS R01GM054778Aug 1, 1997 - Sep 14, 1998
    Role: Principal Investigator
    Analysis of MYST Family Acetyltransferase Functions
    NIH/NIGMS R01GM056469Aug 1, 1997 - Sep 14, 1998
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Engineering longevity-design of a synthetic gene oscillator to slow cellular aging. Science. 2023 04 28; 380(6643):376-381. Zhou Z, Liu Y, Feng Y, Klepin S, Tsimring LS, Pillus L, Hasty J, Hao N. PMID: 37104589; PMCID: PMC10249776.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    2. Functional tug of war between kinases, phosphatases, and the Gcn5 acetyltransferase in chromatin and cell cycle checkpoint controls. G3 (Bethesda). 2023 04 11; 13(4). Liu Q, Pillus L, Petty EL. PMID: 36772957; PMCID: PMC10085806.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    3. Age-dependent aggregation of ribosomal RNA-binding proteins links deterioration in chromatin stability with challenges to proteostasis. Elife. 2022 Oct 04; 11. Paxman J, Zhou Z, O'Laughlin R, Liu Y, Li Y, Tian W, Su H, Jiang Y, Holness SE, Stasiowski E, Tsimring LS, Pillus L, Hasty J, Hao N. PMID: 36194205; PMCID: PMC9578700.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    4. Cell cycle roles for GCN5 revealed through genetic suppression. Biochim Biophys Acta Gene Regul Mech. 2021 02; 1864(2):194625. Petty EL, Pillus L. PMID: 32798737.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    5. A programmable fate decision landscape underlies single-cell aging in yeast. Science. 2020 Jul 17; 369(6501):325-329. Li Y, Jiang Y, Paxman J, O'Laughlin R, Klepin S, Zhu Y, Pillus L, Tsimring LS, Hasty J, Hao N. PMID: 32675375; PMCID: PMC7437498.
      View in: PubMed   Mentions: 41     Fields:    Translation:AnimalsCells
    6. Advances in quantitative biology methods for studying replicative aging in Saccharomyces cerevisiae. Transl Med Aging. 2020; 4:151-160. O'Laughlin R, Jin M, Li Y, Pillus L, Tsimring LS, Hasty J, Hao N. PMID: 33880425; PMCID: PMC8054985.
      View in: PubMed   Mentions: 8  
    7. Divergent Aging of Isogenic Yeast Cells Revealed through Single-Cell Phenotypic Dynamics. Cell Syst. 2019 03 27; 8(3):242-253.e3. Jin M, Li Y, O'Laughlin R, Bittihn P, Pillus L, Tsimring LS, Hasty J, Hao N. PMID: 30852250; PMCID: PMC6514117.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    8. Connecting GCN5's centromeric SAGA to the mitotic tension-sensing checkpoint. Mol Biol Cell. 2018 09 01; 29(18):2201-2212. Petty EL, Evpak M, Pillus L. PMID: 29995571; PMCID: PMC6249797.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    9. Multigenerational silencing dynamics control cell aging. Proc Natl Acad Sci U S A. 2017 10 17; 114(42):11253-11258. Li Y, Jin M, O'Laughlin R, Bittihn P, Tsimring LS, Pillus L, Hasty J, Hao N. PMID: 29073021; PMCID: PMC5651738.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    10. Critical genomic regulation mediated by Enhancer of Polycomb. Curr Genet. 2018 Feb; 64(1):147-154. Searle NE, Pillus L. PMID: 28884217; PMCID: PMC6287951.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    11. Phosphorylation of the 19S regulatory particle ATPase subunit, Rpt6, modifies susceptibility to proteotoxic stress and protein aggregation. PLoS One. 2017; 12(6):e0179893. Marquez-Lona EM, Torres-Machorro AL, Gonzales FR, Pillus L, Patrick GN. PMID: 28662109; PMCID: PMC5491056.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    12. The replicative lifespan-extending deletion of SGF73 results in altered ribosomal gene expression in yeast. Aging Cell. 2017 08; 16(4):785-796. Mason AG, Garza RM, McCormick MA, Patel B, Kennedy BK, Pillus L, La Spada AR. PMID: 28568901; PMCID: PMC5506417.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    13. Chromatin Regulation by the NuA4 Acetyltransferase Complex Is Mediated by Essential Interactions Between Enhancer of Polycomb (Epl1) and Esa1. Genetics. 2017 03; 205(3):1125-1137. Searle NE, Torres-Machorro AL, Pillus L. PMID: 28108589; PMCID: PMC5340328.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    14. Promotion of Cell Viability and Histone Gene Expression by the Acetyltransferase Gcn5 and the Protein Phosphatase PP2A in Saccharomyces cerevisiae. Genetics. 2016 08; 203(4):1693-707. Petty EL, Lafon A, Tomlinson SL, Mendelsohn BA, Pillus L. PMID: 27317677; PMCID: PMC4981271.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    15. Functions for diverse metabolic activities in heterochromatin. Proc Natl Acad Sci U S A. 2016 Mar 15; 113(11):E1526-35. Su XB, Pillus L. PMID: 26936955; PMCID: PMC4801238.
      View in: PubMed   Mentions: 8     Fields:    Translation:Cells
    16. The Set3 Complex Antagonizes the MYST Acetyltransferase Esa1 in the DNA Damage Response. Mol Cell Biol. 2015 Nov; 35(21):3714-25. Torres-Machorro AL, Clark LG, Chang CS, Pillus L. PMID: 26303527; PMCID: PMC4589593.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    17. A moonlighting metabolic protein influences repair at DNA double-stranded breaks. Nucleic Acids Res. 2015 Feb 18; 43(3):1646-58. Torres-Machorro AL, Aris JP, Pillus L. PMID: 25628362; PMCID: PMC4330366.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    18. Tyrosine phosphorylation of histone H2A by CK2 regulates transcriptional elongation. Nature. 2014 Dec 11; 516(7530):267-71. Basnet H, Su XB, Tan Y, Meisenhelder J, Merkurjev D, Ohgi KA, Hunter T, Pillus L, Rosenfeld MG. PMID: 25252977; PMCID: PMC4461219.
      View in: PubMed   Mentions: 62     Fields:    Translation:HumansAnimalsCells
    19. The SAGA histone deubiquitinase module controls yeast replicative lifespan via Sir2 interaction. Cell Rep. 2014 Jul 24; 8(2):477-86. McCormick MA, Mason AG, Guyenet SJ, Dang W, Garza RM, Ting MK, Moller RM, Berger SL, Kaeberlein M, Pillus L, La Spada AR, Kennedy BK. PMID: 25043177; PMCID: PMC4284099.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    20. Bypassing the requirement for an essential MYST acetyltransferase. Genetics. 2014 Jul; 197(3):851-63. Torres-Machorro AL, Pillus L. PMID: 24831819; PMCID: PMC4096366.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    21. Unexpected function of the glucanosyltransferase Gas1 in the DNA damage response linked to histone H3 acetyltransferases in Saccharomyces cerevisiae. Genetics. 2014 Apr; 196(4):1029-39. Eustice M, Pillus L. PMID: 24532730; PMCID: PMC3982697.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    22. Balancing chromatin remodeling and histone modifications in transcription. Trends Genet. 2013 Nov; 29(11):621-9. Petty E, Pillus L. PMID: 23870137; PMCID: PMC4408995.
      View in: PubMed   Mentions: 51     Fields:    Translation:AnimalsCells
    23. STUbLs in chromatin and genome stability. Biopolymers. 2013 Feb; 99(2):146-54. Garza R, Pillus L. PMID: 23175389; PMCID: PMC3507437.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    24. Decoupling epigenetic and genetic effects through systematic analysis of gene position. Cell Rep. 2013 Jan 31; 3(1):128-37. Chen M, Licon K, Otsuka R, Pillus L, Ideker T. PMID: 23291096; PMCID: PMC3563736.
      View in: PubMed   Mentions: 31     Fields:    Translation:AnimalsCells
    25. Functional antagonism between Sas3 and Gcn5 acetyltransferases and ISWI chromatin remodelers. PLoS Genet. 2012; 8(10):e1002994. Lafon A, Petty E, Pillus L. PMID: 23055944; PMCID: PMC3464200.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    26. Suppression analysis of esa1 mutants in Saccharomyces cerevisiae links NAB3 to transcriptional silencing and nucleolar functions. G3 (Bethesda). 2012 Oct; 2(10):1223-32. Chang CS, Clarke A, Pillus L. PMID: 23050233; PMCID: PMC3464115.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    27. Homocitrate synthase connects amino acid metabolism to chromatin functions through Esa1 and DNA damage. Genes Dev. 2010 Sep 01; 24(17):1903-13. Scott EM, Pillus L. PMID: 20810648; PMCID: PMC2932972.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    28. Structural basis for L-lysine feedback inhibition of homocitrate synthase. J Biol Chem. 2010 Apr 02; 285(14):10446-53. Bulfer SL, Scott EM, Pillus L, Trievel RC. PMID: 20089861; PMCID: PMC2856251.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    29. Crystal structure and functional analysis of homocitrate synthase, an essential enzyme in lysine biosynthesis. J Biol Chem. 2009 Dec 18; 284(51):35769-80. Bulfer SL, Scott EM, Couture JF, Pillus L, Trievel RC. PMID: 19776021; PMCID: PMC2791007.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    30. The SAGA subunit Ada2 functions in transcriptional silencing. Mol Cell Biol. 2009 Nov; 29(22):6033-45. Jacobson S, Pillus L. PMID: 19737915; PMCID: PMC2772568.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    31. Collaboration between the essential Esa1 acetyltransferase and the Rpd3 deacetylase is mediated by H4K12 histone acetylation in Saccharomyces cerevisiae. Genetics. 2009 Sep; 183(1):149-60. Chang CS, Pillus L. PMID: 19596907; PMCID: PMC2746140.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    32. The glucanosyltransferase Gas1 functions in transcriptional silencing. Proc Natl Acad Sci U S A. 2009 Jul 07; 106(27):11224-9. Koch MR, Pillus L. PMID: 19541632; PMCID: PMC2708717.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    33. Dynamic reprogramming of transcription factors to and from the subtelomere. Genome Res. 2009 Jun; 19(6):1014-25. Mak HC, Pillus L, Ideker T. PMID: 19372386; PMCID: PMC2694488.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    34. Identifying critical non-catalytic residues that modulate protein kinase A activity. PLoS One. 2009; 4(3):e4746. Kennedy EJ, Yang J, Pillus L, Taylor SS, Ghosh G. PMID: 19270744; PMCID: PMC2650257.
      View in: PubMed   Mentions: 11     Fields:    Translation:Animals
    35. MYSTs mark chromatin for chromosomal functions. Curr Opin Cell Biol. 2008 Jun; 20(3):326-33. Pillus L. PMID: 18511253; PMCID: PMC2717219.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    36. Slx5 promotes transcriptional silencing and is required for robust growth in the absence of Sir2. Mol Cell Biol. 2008 Feb; 28(4):1361-72. Darst RP, Garcia SN, Koch MR, Pillus L. PMID: 18086879; PMCID: PMC2258744.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    37. New nomenclature for chromatin-modifying enzymes. Cell. 2007 Nov 16; 131(4):633-6. Allis CD, Berger SL, Cote J, Dent S, Jenuwien T, Kouzarides T, Pillus L, Reinberg D, Shi Y, Shiekhattar R, Shilatifard A, Workman J, Zhang Y. PMID: 18022353.
      View in: PubMed   Mentions: 443     Fields:    Translation:HumansAnimalsCells
    38. Identification of functionally distinct regions that mediate biological activity of the protein kinase a homolog Tpk2. J Biol Chem. 2008 Jan 11; 283(2):1084-93. Kennedy EJ, Ghosh G, Pillus L. PMID: 17971450.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    39. MYST opportunities for growth control: yeast genes illuminate human cancer gene functions. Oncogene. 2007 Aug 13; 26(37):5373-84. Lafon A, Chang CS, Scott EM, Jacobson SJ, Pillus L. PMID: 17694079.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansAnimalsCells
    40. Nuclear export modulates the cytoplasmic Sir2 homologue Hst2. EMBO Rep. 2006 Dec; 7(12):1247-51. Wilson JM, Le VQ, Zimmerman C, Marmorstein R, Pillus L. PMID: 17110954; PMCID: PMC1794688.
      View in: PubMed   Mentions: 31     Fields:    Translation:AnimalsCells
    41. Chromatin-modifiying enzymes are essential when the Saccharomyces cerevisiae morphogenesis checkpoint is constitutively activated. Genetics. 2006 Nov; 174(3):1135-49. Ruault M, Pillus L. PMID: 16951088; PMCID: PMC1667082.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    42. Distinct roles for the essential MYST family HAT Esa1p in transcriptional silencing. Mol Biol Cell. 2006 Apr; 17(4):1744-57. Clarke AS, Samal E, Pillus L. PMID: 16436512; PMCID: PMC1415314.
      View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
    43. Pho5p and newly identified nucleotide pyrophosphatases/ phosphodiesterases regulate extracellular nucleotide phosphate metabolism in Saccharomyces cerevisiae. Eukaryot Cell. 2005 Nov; 4(11):1892-901. Kennedy EJ, Pillus L, Ghosh G. PMID: 16278456; PMCID: PMC1287867.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    44. Genomewide analysis of nucleosome density histone acetylation and HDAC function in fission yeast. EMBO J. 2005 Aug 17; 24(16):2906-18. Wirén M, Silverstein RA, Sinha I, Walfridsson J, Lee HM, Laurenson P, Pillus L, Robyr D, Grunstein M, Ekwall K. PMID: 16079916; PMCID: PMC1187943.
      View in: PubMed   Mentions: 77     Fields:    Translation:AnimalsCells
    45. Histone H3 phosphorylation can promote TBP recruitment through distinct promoter-specific mechanisms. EMBO J. 2005 Mar 09; 24(5):997-1008. Lo WS, Gamache ER, Henry KW, Yang D, Pillus L, Berger SL. PMID: 15719021; PMCID: PMC554127.
      View in: PubMed   Mentions: 46     Fields:    Translation:AnimalsCells
    46. Conserved locus-specific silencing functions of Schizosaccharomyces pombe sir2+. Genetics. 2005 Mar; 169(3):1243-60. Freeman-Cook LL, Gómez EB, Spedale EJ, Marlett J, Forsburg SL, Pillus L, Laurenson P. PMID: 15545655; PMCID: PMC1449530.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    47. Molecular requirements for gene expression mediated by targeted histone acetyltransferases. Mol Cell Biol. 2004 Jul; 24(13):6029-39. Jacobson S, Pillus L. PMID: 15199156; PMCID: PMC480887.
      View in: PubMed   Mentions: 10     Fields:    Translation:Cells
    48. SIR1 and the origin of epigenetic states in Saccharomyces cerevisiae. Cold Spring Harb Symp Quant Biol. 2004; 69:259-65. Pillus L, Rine J. PMID: 16117657.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    49. Functional analyses of chromatin modifications in yeast. Methods Enzymol. 2004; 377:3-55. Jacobson SJ, Laurenson PM, Pillus L. PMID: 14979016.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    50. The Sir4 C-terminal coiled coil is required for telomeric and mating type silencing in Saccharomyces cerevisiae. J Mol Biol. 2003 Dec 05; 334(4):769-80. Murphy GA, Spedale EJ, Powell ST, Pillus L, Schultz SC, Chen L. PMID: 14636601.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    51. Transcriptional activation via sequential histone H2B ubiquitylation and deubiquitylation, mediated by SAGA-associated Ubp8. Genes Dev. 2003 Nov 01; 17(21):2648-63. Henry KW, Wyce A, Lo WS, Duggan LJ, Emre NC, Kao CF, Pillus L, Shilatifard A, Osley MA, Berger SL. PMID: 14563679; PMCID: PMC280615.
      View in: PubMed   Mentions: 341     Fields:    Translation:AnimalsCells
    52. Structural basis for histone and phosphohistone binding by the GCN5 histone acetyltransferase. Mol Cell. 2003 Aug; 12(2):461-73. Clements A, Poux AN, Lo WS, Pillus L, Berger SL, Marmorstein R. PMID: 14536085.
      View in: PubMed   Mentions: 60     Fields:    Translation:AnimalsCells
    53. Telomerase-independent proliferation is influenced by cell type in Saccharomyces cerevisiae. Genetics. 2003 Jul; 164(3):909-21. Lowell JE, Roughton AI, Lundblad V, Pillus L. PMID: 12871903; PMCID: PMC1462614.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    54. Histone deacetylation by Sir2 generates a transcriptionally repressed nucleoprotein complex. Proc Natl Acad Sci U S A. 2003 Feb 18; 100(4):1609-14. Parsons XH, Garcia SN, Pillus L, Kadonaga JT. PMID: 12571358; PMCID: PMC149880.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    55. Histone H3 specific acetyltransferases are essential for cell cycle progression. Genes Dev. 2001 Dec 01; 15(23):3144-54. Howe L, Auston D, Grant P, John S, Cook RG, Workman JL, Pillus L. PMID: 11731478; PMCID: PMC312843.
      View in: PubMed   Mentions: 108     Fields:    Translation:AnimalsCells
    56. Deciphering NAD-dependent deacetylases. Cell. 2001 Apr 20; 105(2):161-4. Dutnall RN, Pillus L. PMID: 11336664.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    57. Two classes of sir3 mutants enhance the sir1 mutant mating defect and abolish telomeric silencing in Saccharomyces cerevisiae. Genetics. 2000 Jun; 155(2):509-22. Stone EM, Reifsnyder C, McVey M, Gazo B, Pillus L. PMID: 10835377; PMCID: PMC1461112.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    58. The silencing protein SIR2 and its homologs are NAD-dependent protein deacetylases. Proc Natl Acad Sci U S A. 2000 May 23; 97(11):5807-11. Landry J, Sutton A, Tafrov ST, Heller RC, Stebbins J, Pillus L, Sternglanz R. PMID: 10811920; PMCID: PMC18515.
      View in: PubMed   Mentions: 404     Fields:    Translation:AnimalsCells
    59. MAP kinase signaling induces nuclear reorganization in budding yeast. Curr Biol. 2000 Apr 06; 10(7):373-82. Stone EM, Heun P, Laroche T, Pillus L, Gasser SM. PMID: 10753745.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    60. The Schizosaccharomyces pombe hst4(+) gene is a SIR2 homologue with silencing and centromeric functions. Mol Biol Cell. 1999 Oct; 10(10):3171-86. Freeman-Cook LL, Sherman JM, Brachmann CB, Allshire RC, Boeke JD, Pillus L. PMID: 10512858; PMCID: PMC25575.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    61. NuA4, an essential transcription adaptor/histone H4 acetyltransferase complex containing Esa1p and the ATM-related cofactor Tra1p. EMBO J. 1999 Sep 15; 18(18):5108-19. Allard S, Utley RT, Savard J, Clarke A, Grant P, Brandl CJ, Pillus L, Workman JL, Côté J. PMID: 10487762; PMCID: PMC1171581.
      View in: PubMed   Mentions: 220     Fields:    Translation:HumansAnimalsCells
    62. The conserved core of a human SIR2 homologue functions in yeast silencing. Mol Biol Cell. 1999 Sep; 10(9):3045-59. Sherman JM, Stone EM, Freeman-Cook LL, Brachmann CB, Boeke JD, Pillus L. PMID: 10473645; PMCID: PMC25551.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansAnimalsCells
    63. Net results of nucleolar dynamics. Cell. 1999 Jun 25; 97(7):825-8. Garcia SN, Pillus L. PMID: 10399910.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    64. Modifying chromatin and concepts of cancer. Curr Opin Genet Dev. 1999 Apr; 9(2):175-84. Jacobson S, Pillus L. PMID: 10322138.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    65. Esa1p is an essential histone acetyltransferase required for cell cycle progression. Mol Cell Biol. 1999 Apr; 19(4):2515-26. Clarke AS, Lowell JE, Jacobson SJ, Pillus L. PMID: 10082517; PMCID: PMC84044.
      View in: PubMed   Mentions: 184     Fields:    Translation:AnimalsCells
    66. Distribution of a limited Sir2 protein pool regulates the strength of yeast rDNA silencing and is modulated by Sir4p. Genetics. 1998 Jul; 149(3):1205-19. Smith JS, Brachmann CB, Pillus L, Boeke JD. PMID: 9649515; PMCID: PMC1460222.
      View in: PubMed   Mentions: 77     Fields:    Translation:AnimalsCells
    67. Silent chromatin in yeast: an orchestrated medley featuring Sir3p [corrected]. Bioessays. 1998 Jan; 20(1):30-40. Stone EM, Pillus L. PMID: 9504045.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    68. Telomere tales: chromatin, telomerase and telomere function in Saccharomyces cerevisiae. Cell Mol Life Sci. 1998 Jan; 54(1):32-49. Lowell JE, Pillus L. PMID: 9487385.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    69. SET1, a yeast member of the trithorax family, functions in transcriptional silencing and diverse cellular processes. Mol Biol Cell. 1997 Dec; 8(12):2421-36. Nislow C, Ray E, Pillus L. PMID: 9398665; PMCID: PMC25717.
      View in: PubMed   Mentions: 117     Fields:    Translation:HumansAnimalsCells
    70. An uncertain silence. Trends Genet. 1997 Aug; 13(8):308-13. Sherman JM, Pillus L. PMID: 9260516.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    71. Mammalian homologues of the Polycomb-group gene Enhancer of zeste mediate gene silencing in Drosophila heterochromatin and at S. cerevisiae telomeres. EMBO J. 1997 Jun 02; 16(11):3219-32. Laible G, Wolf A, Dorn R, Reuter G, Nislow C, Lebersorger A, Popkin D, Pillus L, Jenuwein T. PMID: 9214638; PMCID: PMC1169939.
      View in: PubMed   Mentions: 112     Fields:    Translation:HumansAnimalsCells
    72. Yeast SAS silencing genes and human genes associated with AML and HIV-1 Tat interactions are homologous with acetyltransferases. Nat Genet. 1997 May; 16(1):109. Reifnyder C, Lowell J, Clarke A, Pillus L. PMID: 9140406.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    73. Activation of an MAP kinase cascade leads to Sir3p hyperphosphorylation and strengthens transcriptional silencing. J Cell Biol. 1996 Nov; 135(3):571-83. Stone EM, Pillus L. PMID: 8909534; PMCID: PMC2121063.
      View in: PubMed   Mentions: 37     Fields:    Translation:AnimalsCells
    74. Yeast SAS silencing genes and human genes associated with AML and HIV-1 Tat interactions are homologous with acetyltransferases. Nat Genet. 1996 Sep; 14(1):42-9. Reifsnyder C, Lowell J, Clarke A, Pillus L. PMID: 8782818.
      View in: PubMed   Mentions: 105     Fields:    Translation:HumansAnimalsCells
    75. The SIR2 gene family, conserved from bacteria to humans, functions in silencing, cell cycle progression, and chromosome stability. Genes Dev. 1995 Dec 01; 9(23):2888-902. Brachmann CB, Sherman JM, Devine SE, Cameron EE, Pillus L, Boeke JD. PMID: 7498786.
      View in: PubMed   Mentions: 264     Fields:    Translation:HumansAnimalsCells
    76. Silencing speaks up. Cell. 1994 Mar 25; 76(6):963-6. Rivier DH, Pillus L. PMID: 8137430.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    77. SIR3 and SIR4 proteins are required for the positioning and integrity of yeast telomeres. Cell. 1993 Nov 05; 75(3):543-55. Palladino F, Laroche T, Gilson E, Axelrod A, Pillus L, Gasser SM. PMID: 8221893.
      View in: PubMed   Mentions: 166     Fields:    Translation:AnimalsCells
    78. The positioning of yeast telomeres depends on SIR3, SIR4, and the integrity of the nuclear membrane. Cold Spring Harb Symp Quant Biol. 1993; 58:733-46. Palladino F, Laroche T, Gilson E, Pillus L, Gasser SM. PMID: 7956091.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    79. An acquired state: epigenetic mechanisms in transcription. Curr Opin Cell Biol. 1992 Jun; 4(3):453-8. Pillus L. PMID: 1497916.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    80. Epigenetic inheritance of transcriptional states in S. cerevisiae. Cell. 1989 Nov 17; 59(4):637-47. Pillus L, Rine J. PMID: 2684414.
      View in: PubMed   Mentions: 158     Fields:    Translation:AnimalsCells
    81. Two functional alpha-tubulin genes of the yeast Saccharomyces cerevisiae encode divergent proteins. Mol Cell Biol. 1986 Nov; 6(11):3711-21. Schatz PJ, Pillus L, Grisafi P, Solomon F, Botstein D. PMID: 3025610; PMCID: PMC367132.
      View in: PubMed   Mentions: 80     Fields:    Translation:AnimalsCells
    82. Components of microtubular structures in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A. 1986 Apr; 83(8):2468-72. Pillus L, Solomon F. PMID: 3517870; PMCID: PMC323319.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    83. A chicken-yeast chimeric beta-tubulin protein is incorporated into mouse microtubules in vivo. Cell. 1986 Feb 14; 44(3):461-8. Bond JF, Fridovich-Keil JL, Pillus L, Mulligan RC, Solomon F. PMID: 3753663.
      View in: PubMed   Mentions: 72     Fields:    Translation:AnimalsCells
    84. Near-neighbor analysis of spindle microtubules in the alga Ochromonas. Eur J Cell Biol. 1983 Mar; 30(1):9-17. Tippit DH, Pillus L, Pickett-Heaps JD. PMID: 6682766.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    85. Organization of spindle microtubules in Ochromonas danica. J Cell Biol. 1980 Dec; 87(3 Pt 1):531-45. Tippit DH, Pillus L, Pickett-Heaps J. PMID: 7462315; PMCID: PMC2110780.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
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