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Maike Sander

TitleAdjunct Professor
InstitutionUniversity of California San Diego
DepartmentCellular and Molecular Medicine
Address9500 Gilman Drive #0695
La Jolla CA 92093
Phone858-246-0843
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    Collapse Overview 
    Collapse Overview
    Our laboratory studies the molecular mechanisms that underlie the differentiation, function and regeneration of cells in the pancreas. We investigate these mechanisms in the context of normal physiology, diabetes and cancer. In our research, we combine of variety experimental systems, including mouse genetics, a human embryonic stem cell-based in vitro differentiation platform, as well as genomic and biochemical approaches.
    In recent studies, we mapped dynamic changes in the transcriptome and epigenome during the progression of pluripotent stem cells toward the pancreatic fate and discovered how chromatin remodeling events prepare developmental precursors to receive and correctly interpret organ-inductive signals. In current work, we are exploring how the cellular environment shapes the epigenome and thereby influences cellular phenotypes in the pancreas. Such knowledge will likely yield an understanding of the mechanisms underlying diseases influenced by both environmental and genetic factors, such as diabetes.

    Research Focus Areas:

  • Developmental Biology

  • Genetics and Genomics

  • Gene Expression and Regulation

  • Stem Cell Biology



  • Collapse Research 
    Collapse Research Activities and Funding
    Fine-mapping and functional analysis of T1D-associated variants
    NIH/NIDDK DP3DK112155Sep 30, 2016 - Jun 30, 2021
    Role: Principal Investigator
    Functional Analysis of T2D Associated Non-coding SNPs
    NIH/NIDDK U01DK105541May 1, 2015 - Apr 30, 2020
    Role: Principal Investigator
    A novel mouse model to identify biomarkers of IPMN formation and progression
    NIH/NCI R21CA194839Apr 1, 2015 - Mar 31, 2017
    Role: Principal Investigator
    A 3-D biomimetic human islet to model beta cell function in health and disease
    NIH/NIDDK UC4DK104202Sep 20, 2014 - Jun 30, 2019
    Role: Principal Investigator
    Epigenetic strategies for the in vitro generation of replacement beta cells
    NIH/NIDDK U01DK089567Sep 17, 2010 - Jun 30, 2014
    Role: Principal Investigator
    Mechanisms of pancreatic endocrine cell differentiation
    NIH/NIDDK R01DK078803Sep 1, 2007 - Jun 30, 2017
    Role: Principal Investigator
    Epigenetic determinants of beta cell development and function
    NIH/NIDDK R01DK068471Jun 1, 2004 - Jul 31, 2021
    Role: Principal Investigator
    Diabetes Research Center (DRC)
    NIH/NIDDK P30DK063491Dec 1, 2002 - Apr 30, 2018
    Role: Co-Investigator
    IVEM and Image Analysis Resource
    NIH/NCRR P41RR004050Dec 12, 1988 - Mar 31, 2014
    Role: Co-Investigator

    Collapse ORNG Applications 
    Collapse Websites

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Das KK, Heeg S, Pitarresi JR, Reichert M, Bakir B, Takano S, Kopp JL, Wahl-Feuerstein A, Hicks P, Sander M, Rustgi AK. ETV5 regulates ductal morphogenesis with Sox9 and is critical for regeneration from pancreatitis. Dev Dyn. 2018 Mar 13. PMID: 29532564.
      View in: PubMed
    2. Lee AYL, Dubois CL, Sarai K, Zarei S, Schaeffer DF, Sander M, Kopp JL. Cell of origin affects tumour development and phenotype in pancreatic ductal adenocarcinoma. Gut. 2018 Jan 23. PMID: 29363536.
      View in: PubMed
    3. Kopp JL, Dubois CL, Schaeffer DF, Samani A, Taghizadeh F, Cowan RW, Rhim AD, Stiles BL, Valasek M, Sander M. Loss of Pten and Activation of Kras Synergistically Induce Formation of Intraductal Papillary Mucinous Neoplasia From Pancreatic Ductal Cells in Mice. Gastroenterology. 2018 04; 154(5):1509-1523.e5. PMID: 29273451.
      View in: PubMed
    4. Carrano AC, Mulas F, Zeng C, Sander M. Interrogating islets in health and disease with single-cell technologies. Mol Metab. 2017 Sep; 6(9):991-1001. PMID: 28951823.
      View in: PubMed
    5. Zeng C, Mulas F, Sui Y, Guan T, Miller N, Tan Y, Liu F, Jin W, Carrano AC, Huising MO, Shirihai OS, Yeo GW, Sander M. Pseudotemporal Ordering of Single Cells Reveals Metabolic Control of Postnatal ß Cell Proliferation. Cell Metab. 2017 May 02; 25(5):1160-1175.e11. PMID: 28467932.
      View in: PubMed
    6. Ediger BN, Lim HW, Juliana C, Groff DN, Williams LT, Dominguez G, Liu JH, Taylor BL, Walp ER, Kameswaran V, Yang J, Liu C, Hunter CS, Kaestner KH, Naji A, Li C, Sander M, Stein R, Sussel L, Won KJ, May CL, Stoffers DA. LIM domain-binding 1 maintains the terminally differentiated state of pancreatic ß cells. J Clin Invest. 2017 Jan 03; 127(1):215-229. PMID: 27941246.
      View in: PubMed
    7. Benthuysen JR, Carrano AC, Sander M. Advances in ß cell replacement and regeneration strategies for treating diabetes. J Clin Invest. 2016 Oct 03; 126(10):3651-3660. PMID: 27694741.
      View in: PubMed
    8. Barrionuevo FJ, Hurtado A, Kim GJ, Real FM, Bakkali M, Kopp JL, Sander M, Scherer G, Burgos M, Jiménez R. Sox9 and Sox8 protect the adult testis from male-to-female genetic reprogramming and complete degeneration. Elife. 2016 06 21; 5. PMID: 27328324; PMCID: PMC4945155.
    9. Fox RG, Lytle NK, Jaquish DV, Park FD, Ito T, Bajaj J, Koechlein CS, Zimdahl B, Yano M, Kopp J, Kritzik M, Sicklick J, Sander M, Grandgenett PM, Hollingsworth MA, Shibata S, Pizzo D, Valasek M, Sasik R, Scadeng M, Okano H, Kim Y, MacLeod AR, Lowy AM, Reya T. Image-based detection and targeting of therapy resistance in pancreatic adenocarcinoma. Nature. 2016 06 16; 534(7607):407-411. PMID: 27281208; PMCID: PMC4998062 [Available on 12/16/16].
    10. Wortham M, Sander M. High T Gives ß Cells a Boost. Cell Metab. 2016 May 10; 23(5):761-3. PMID: 27166938.
      View in: PubMed
    11. Kopp JL, Grompe M, Sander M. Stem cells versus plasticity in liver and pancreas regeneration. Nat Cell Biol. 2016 Mar; 18(3):238-45. PMID: 26911907.
      View in: PubMed
    12. Shih HP, Panlasigui D, Cirulli V, Sander M. ECM Signaling Regulates Collective Cellular Dynamics to Control Pancreas Branching Morphogenesis. Cell Rep. 2016 Jan 12; 14(2):169-79. PMID: 26748698; PMCID: PMC4715768.
    13. Shih HP, Seymour PA, Patel NA, Xie R, Wang A, Liu PP, Yeo GW, Magnuson MA, Sander M. A Gene Regulatory Network Cooperatively Controlled by Pdx1 and Sox9 Governs Lineage Allocation of Foregut Progenitor Cells. Cell Rep. 2015 Oct 13; 13(2):326-36. PMID: 26440894; PMCID: PMC4607666.
    14. Thélie A, Desiderio S, Hanotel J, Quigley I, Van Driessche B, Rodari A, Borromeo MD, Kricha S, Lahaye F, Croce J, Cerda-Moya G, Ordoño Fernandez J, Bolle B, Lewis KE, Sander M, Pierani A, Schubert M, Johnson JE, Kintner CR, Pieler T, Van Lint C, Henningfeld KA, Bellefroid EJ, Van Campenhout C. Prdm12 specifies V1 interneurons through cross-repressive interactions with Dbx1 and Nkx6 genes in Xenopus. Development. 2015 Oct 01; 142(19):3416-28. PMID: 26443638; PMCID: PMC4631751.
    15. Font-Burgada J, Shalapour S, Ramaswamy S, Hsueh B, Rossell D, Umemura A, Taniguchi K, Nakagawa H, Valasek MA, Ye L, Kopp JL, Sander M, Carter H, Deisseroth K, Verma IM, Karin M. Hybrid Periportal Hepatocytes Regenerate the Injured Liver without Giving Rise to Cancer. Cell. 2015 Aug 13; 162(4):766-79. PMID: 26276631; PMCID: PMC4545590.
    16. Jörs S, Jeliazkova P, Ringelhan M, Thalhammer J, Dürl S, Ferrer J, Sander M, Heikenwalder M, Schmid RM, Siveke JT, Geisler F. Lineage fate of ductular reactions in liver injury and carcinogenesis. J Clin Invest. 2015 Jun; 125(6):2445-57. PMID: 25915586.
      View in: PubMed
    17. Wang A, Yue F, Li Y, Xie R, Harper T, Patel NA, Muth K, Palmer J, Qiu Y, Wang J, Lam DK, Raum JC, Stoffers DA, Ren B, Sander M. Epigenetic priming of enhancers predicts developmental competence of hESC-derived endodermal lineage intermediates. Cell Stem Cell. 2015 Apr 02; 16(4):386-99. PMID: 25842977; PMCID: PMC4478079.
    18. De Vas MG, Kopp JL, Heliot C, Sander M, Cereghini S, Haumaitre C. Hnf1b controls pancreas morphogenesis and the generation of Ngn3+ endocrine progenitors. Development. 2015 Mar 01; 142(5):871-82. PMID: 25715395; PMCID: PMC4352981.
    19. Xie R, Carrano AC, Sander M. A systems view of epigenetic networks regulating pancreas development and ß-cell function. Wiley Interdiscip Rev Syst Biol Med. 2015 Jan-Feb; 7(1):1-11. PMID: 25644779; PMCID: PMC4339621.
    20. Malhotra GK, Zhao X, Edwards E, Kopp JL, Naramura M, Sander M, Band H, Band V. The role of Sox9 in mouse mammary gland development and maintenance of mammary stem and luminal progenitor cells. BMC Dev Biol. 2014 Dec 20; 14:47. PMID: 25527186; PMCID: PMC4297388.
    21. Zhao X, Chen Y, Zhu Q, Huang H, Teng P, Zheng K, Hu X, Xie B, Zhang Z, Sander M, Qiu M. Control of astrocyte progenitor specification, migration and maturation by Nkx6.1 homeodomain transcription factor. PLoS One. 2014; 9(10):e109171. PMID: 25285789; PMCID: PMC4186865.
    22. Taylor BL, Benthuysen J, Sander M. Postnatal ß-cell proliferation and mass expansion is dependent on the transcription factor Nkx6.1. Diabetes. 2015 Mar; 64(3):897-903. PMID: 25277396; PMCID: PMC4338594.
    23. Benitah SA, Bracken A, Dou Y, Huangfu D, Ivanova N, Koseki H, Laurent L, Lim DA, Meshorer E, Pombo A, Sander M, Xu GL. Stem cell epigenetics: looking forward. Cell Stem Cell. 2014 Jun 05; 14(6):706-9. PMID: 25032261.
      View in: PubMed
    24. Kanda S, Tanigawa S, Ohmori T, Taguchi A, Kudo K, Suzuki Y, Sato Y, Hino S, Sander M, Perantoni AO, Sugano S, Nakao M, Nishinakamura R. Sall1 maintains nephron progenitors and nascent nephrons by acting as both an activator and a repressor. J Am Soc Nephrol. 2014 Nov; 25(11):2584-95. PMID: 24744442; PMCID: PMC4214521.
    25. Shih HP, Sander M. Pancreas development ex vivo: culturing embryonic pancreas explants on permeable culture inserts, with fibronectin-coated glass microwells, or embedded in three-dimensional Matrigel™. Methods Mol Biol. 2014; 1210:229-37. PMID: 25173172; PMCID: PMC4423897.
    26. Kopp JL, Sander M. New insights into the cell lineage of pancreatic ductal adenocarcinoma: evidence for tumor stem cells in premalignant lesions? Gastroenterology. 2014 Jan; 146(1):24-6. PMID: 24275238.
      View in: PubMed
    27. Rockich BE, Hrycaj SM, Shih HP, Nagy MS, Ferguson MA, Kopp JL, Sander M, Wellik DM, Spence JR. Sox9 plays multiple roles in the lung epithelium during branching morphogenesis. Proc Natl Acad Sci U S A. 2013 Nov 19; 110(47):E4456-64. PMID: 24191021; PMCID: PMC3839746.
    28. Taylor BL, Liu FF, Sander M. Nkx6.1 is essential for maintaining the functional state of pancreatic beta cells. Cell Rep. 2013 Sep 26; 4(6):1262-75. PMID: 24035389; PMCID: PMC4058003.
    29. Shih HP, Wang A, Sander M. Pancreas organogenesis: from lineage determination to morphogenesis. Annu Rev Cell Dev Biol. 2013; 29:81-105. PMID: 23909279.
      View in: PubMed
    30. Guo S, Dai C, Guo M, Taylor B, Harmon JS, Sander M, Robertson RP, Powers AC, Stein R. Inactivation of specific ß cell transcription factors in type 2 diabetes. J Clin Invest. 2013 Aug; 123(8):3305-16. PMID: 23863625; PMCID: PMC3726150.
    31. Jin L, Feng T, Shih HP, Zerda R, Luo A, Hsu J, Mahdavi A, Sander M, Tirrell DA, Riggs AD, Ku HT. Colony-forming cells in the adult mouse pancreas are expandable in Matrigel and form endocrine/acinar colonies in laminin hydrogel. Proc Natl Acad Sci U S A. 2013 Mar 05; 110(10):3907-12. PMID: 23431132; PMCID: PMC3593860.
    32. Schaffer AE, Taylor BL, Benthuysen JR, Liu J, Thorel F, Yuan W, Jiao Y, Kaestner KH, Herrera PL, Magnuson MA, May CL, Sander M. Nkx6.1 controls a gene regulatory network required for establishing and maintaining pancreatic Beta cell identity. PLoS Genet. 2013; 9(1):e1003274. PMID: 23382704; PMCID: PMC3561089.
    33. Xie R, Everett LJ, Lim HW, Patel NA, Schug J, Kroon E, Kelly OG, Wang A, D'Amour KA, Robins AJ, Won KJ, Kaestner KH, Sander M. Dynamic chromatin remodeling mediated by polycomb proteins orchestrates pancreatic differentiation of human embryonic stem cells. Cell Stem Cell. 2013 Feb 07; 12(2):224-37. PMID: 23318056; PMCID: PMC3619036.
    34. van der Meulen T, Xie R, Kelly OG, Vale WW, Sander M, Huising MO. Urocortin 3 marks mature human primary and embryonic stem cell-derived pancreatic alpha and beta cells. PLoS One. 2012; 7(12):e52181. PMID: 23251699; PMCID: PMC3522648.
    35. Kopp JL, von Figura G, Mayes E, Liu FF, Dubois CL, Morris JP, Pan FC, Akiyama H, Wright CV, Jensen K, Hebrok M, Sander M. Identification of Sox9-dependent acinar-to-ductal reprogramming as the principal mechanism for initiation of pancreatic ductal adenocarcinoma. Cancer Cell. 2012 Dec 11; 22(6):737-50. PMID: 23201164; PMCID: PMC3568632.
    36. Morán I, Akerman I, van de Bunt M, Xie R, Benazra M, Nammo T, Arnes L, Nakic N, García-Hurtado J, Rodríguez-Seguí S, Pasquali L, Sauty-Colace C, Beucher A, Scharfmann R, van Arensbergen J, Johnson PR, Berry A, Lee C, Harkins T, Gmyr V, Pattou F, Kerr-Conte J, Piemonti L, Berney T, Hanley N, Gloyn AL, Sussel L, Langman L, Brayman KL, Sander M, McCarthy MI, Ravassard P, Ferrer J. Human ß cell transcriptome analysis uncovers lncRNAs that are tissue-specific, dynamically regulated, and abnormally expressed in type 2 diabetes. Cell Metab. 2012 Oct 03; 16(4):435-48. PMID: 23040067.
      View in: PubMed
    37. Seymour PA, Shih HP, Patel NA, Freude KK, Xie R, Lim CJ, Sander M. A Sox9/Fgf feed-forward loop maintains pancreatic organ identity. Development. 2012 Sep; 139(18):3363-72. PMID: 22874919; PMCID: PMC3424044.
    38. Wang A, Sander M. Generating cells of the gastrointestinal system: current approaches and applications for the differentiation of human pluripotent stem cells. J Mol Med (Berl). 2012 Jul; 90(7):763-71. PMID: 22714642.
      View in: PubMed
    39. Shih HP, Kopp JL, Sandhu M, Dubois CL, Seymour PA, Grapin-Botton A, Sander M. A Notch-dependent molecular circuitry initiates pancreatic endocrine and ductal cell differentiation. Development. 2012 Jul; 139(14):2488-99. PMID: 22675211; PMCID: PMC3383226.
    40. Schaffer AE, Yang AJ, Thorel F, Herrera PL, Sander M. Transgenic overexpression of the transcription factor Nkx6.1 in ß-cells of mice does not increase ß-cell proliferation, ß-cell mass, or improve glucose clearance. Mol Endocrinol. 2011 Nov; 25(11):1904-14. PMID: 21964593; PMCID: PMC3198960.
    41. Dubois CL, Shih HP, Seymour PA, Patel NA, Behrmann JM, Ngo V, Sander M. Sox9-haploinsufficiency causes glucose intolerance in mice. PLoS One. 2011; 6(8):e23131. PMID: 21829703; PMCID: PMC3149078.
    42. Carpentier R, Suñer RE, van Hul N, Kopp JL, Beaudry JB, Cordi S, Antoniou A, Raynaud P, Lepreux S, Jacquemin P, Leclercq IA, Sander M, Lemaigre FP. Embryonic ductal plate cells give rise to cholangiocytes, periportal hepatocytes, and adult liver progenitor cells. Gastroenterology. 2011 Oct; 141(4):1432-8, 1438.e1-4. PMID: 21708104; PMCID: PMC3494970.
    43. Kopp JL, Dubois CL, Hao E, Thorel F, Herrera PL, Sander M. Progenitor cell domains in the developing and adult pancreas. Cell Cycle. 2011 Jun 15; 10(12):1921-7. PMID: 21558806; PMCID: PMC3154415.
    44. Dorrell C, Erker L, Schug J, Kopp JL, Canaday PS, Fox AJ, Smirnova O, Duncan AW, Finegold MJ, Sander M, Kaestner KH, Grompe M. Prospective isolation of a bipotential clonogenic liver progenitor cell in adult mice. Genes Dev. 2011 Jun 01; 25(11):1193-203. PMID: 21632826; PMCID: PMC3110957.
    45. Kopp JL, Dubois CL, Schaffer AE, Hao E, Shih HP, Seymour PA, Ma J, Sander M. Sox9+ ductal cells are multipotent progenitors throughout development but do not produce new endocrine cells in the normal or injured adult pancreas. Development. 2011 Feb; 138(4):653-65. PMID: 21266405; PMCID: PMC3026412.
    46. Seymour PA, Sander M. Historical perspective: beginnings of the beta-cell: current perspectives in beta-cell development. Diabetes. 2011 Feb; 60(2):364-76. PMID: 21270248; PMCID: PMC3028333.
    47. Schaffer AE, Freude KK, Nelson SB, Sander M. Nkx6 transcription factors and Ptf1a function as antagonistic lineage determinants in multipotent pancreatic progenitors. Dev Cell. 2010 Jun 15; 18(6):1022-9. PMID: 20627083; PMCID: PMC3133668.
    48. Prakash N, Puelles E, Freude K, Trümbach D, Omodei D, Di Salvio M, Sussel L, Ericson J, Sander M, Simeone A, Wurst W. Nkx6-1 controls the identity and fate of red nucleus and oculomotor neurons in the mouse midbrain. Development. 2009 Aug; 136(15):2545-55. PMID: 19592574; PMCID: PMC2729334.
    49. Wang S, Jensen JN, Seymour PA, Hsu W, Dor Y, Sander M, Magnuson MA, Serup P, Gu G. Sustained Neurog3 expression in hormone-expressing islet cells is required for endocrine maturation and function. Proc Natl Acad Sci U S A. 2009 Jun 16; 106(24):9715-20. PMID: 19487660; PMCID: PMC2701002.
    50. Seymour PA, Freude KK, Dubois CL, Shih HP, Patel NA, Sander M. A dosage-dependent requirement for Sox9 in pancreatic endocrine cell formation. Dev Biol. 2008 Nov 01; 323(1):19-30. PMID: 18723011; PMCID: PMC2879081.
    51. Jonckheere N, Mayes E, Shih HP, Li B, Lioubinski O, Dai X, Sander M. Analysis of mPygo2 mutant mice suggests a requirement for mesenchymal Wnt signaling in pancreatic growth and differentiation. Dev Biol. 2008 Jun 15; 318(2):224-35. PMID: 18452912; PMCID: PMC2478757.
    52. Nelson SB, Schaffer AE, Sander M. The transcription factors Nkx6.1 and Nkx6.2 possess equivalent activities in promoting beta-cell fate specification in Pdx1+ pancreatic progenitor cells. Development. 2007 Jul; 134(13):2491-500. PMID: 17537793.
      View in: PubMed
    53. Seymour PA, Freude KK, Tran MN, Mayes EE, Jensen J, Kist R, Scherer G, Sander M. SOX9 is required for maintenance of the pancreatic progenitor cell pool. Proc Natl Acad Sci U S A. 2007 Feb 06; 104(6):1865-70. PMID: 17267606; PMCID: PMC1794281.
    54. Seymour PA, Sander M. Immunohistochemical detection of beta-galactosidase or green fluorescent protein on tissue sections. Methods Mol Biol. 2007; 411:13-23. PMID: 18287635.
      View in: PubMed
    55. Pedersen JK, Nelson SB, Jorgensen MC, Henseleit KD, Fujitani Y, Wright CV, Sander M, Serup P. Endodermal expression of Nkx6 genes depends differentially on Pdx1. Dev Biol. 2005 Dec 15; 288(2):487-501. PMID: 16297379.
      View in: PubMed
    56. Henseleit KD, Nelson SB, Kuhlbrodt K, Hennings JC, Ericson J, Sander M. NKX6 transcription factor activity is required for alpha- and beta-cell development in the pancreas. Development. 2005 Jul; 132(13):3139-49. PMID: 15944193.
      View in: PubMed
    57. Nelson SB, Janiesch C, Sander M. Expression of Nkx6 genes in the hindbrain and gut of the developing mouse. J Histochem Cytochem. 2005 Jun; 53(6):787-90. PMID: 15928328.
      View in: PubMed
    58. Cai J, Qi Y, Hu X, Tan M, Liu Z, Zhang J, Li Q, Sander M, Qiu M. Generation of oligodendrocyte precursor cells from mouse dorsal spinal cord independent of Nkx6 regulation and Shh signaling. Neuron. 2005 Jan 06; 45(1):41-53. PMID: 15629701.
      View in: PubMed
    59. Mellitzer G, Martín M, Sidhoum-Jenny M, Orvain C, Barths J, Seymour PA, Sander M, Gradwohl G. Pancreatic islet progenitor cells in neurogenin 3-yellow fluorescent protein knock-add-on mice. Mol Endocrinol. 2004 Nov; 18(11):2765-76. PMID: 15297605.
      View in: PubMed
    60. Matsuoka TA, Artner I, Henderson E, Means A, Sander M, Stein R. The MafA transcription factor appears to be responsible for tissue-specific expression of insulin. Proc Natl Acad Sci U S A. 2004 Mar 02; 101(9):2930-3. PMID: 14973194; PMCID: PMC365722.
    61. Liu R, Cai J, Hu X, Tan M, Qi Y, German M, Rubenstein J, Sander M, Qiu M. Region-specific and stage-dependent regulation of Olig gene expression and oligodendrogenesis by Nkx6.1 homeodomain transcription factor. Development. 2003 Dec; 130(25):6221-31. PMID: 14602683.
      View in: PubMed
    62. Müller M, Jabs N, Lorke DE, Fritzsch B, Sander M. Nkx6.1 controls migration and axon pathfinding of cranial branchio-motoneurons. Development. 2003 Dec; 130(23):5815-26. PMID: 14534138.
      View in: PubMed
    63. Pattyn A, Vallstedt A, Dias JM, Sander M, Ericson J. Complementary roles for Nkx6 and Nkx2 class proteins in the establishment of motoneuron identity in the hindbrain. Development. 2003 Sep; 130(17):4149-59. PMID: 12874134.
      View in: PubMed
    64. Lioubinski O, Müller M, Wegner M, Sander M. Expression of Sox transcription factors in the developing mouse pancreas. Dev Dyn. 2003 Jul; 227(3):402-8. PMID: 12815626.
      View in: PubMed