Mark Kamps

TitleEmeritus Professor
InstitutionUniversity of California San Diego
Address9500 Gilman Drive #0723
La Jolla CA 92093
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    Collapse Research 
    Collapse Research Activities and Funding
    Molecular Pathology of Cancer Training Grant
    NIH/NCI T32CA077109Jul 1, 1998 - Jul 31, 2010
    Role: Principal Investigator
    NIH/NHLBI R01HL054451Jun 1, 1995 - May 31, 1999
    Role: Principal Investigator
    Hoxa9, Meis1, and Pbx in Self-renewal and Leukemogenesis
    NIH/NCI R01CA056876Apr 10, 1992 - Nov 30, 2013
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Zhu Y, Gong K, Denholtz M, Chandra V, Kamps M, Alber F, Murre C. Comprehensive characterization of neutrophil genome topology. Genes Dev. 2017 01 15; 31(2):141-153. PMID: 28167501.
      View in: PubMed
    2. Li D, Yang H, Nan H, Liu P, Pang S, Zhao Q, Karni R, Kamps M, Xu Y, Zhou J, Wiedmer T, Sims PJ, Wang F. Identification of key regulatory pathways of myeloid differentiation using an mESC-based karyotypically normal cell model. Blood. 2012 Dec 06; 120(24):4712-9. PMID: 23086752; PMCID: PMC3520617.
    3. Miles LA, Lighvani S, Baik N, Andronicos NM, Chen EI, Parmer CM, Khaldoyanidi S, Diggs JE, Kiosses WB, Kamps M, Yates JR, Parmer RJ. The plasminogen receptor, Plg-R(KT), and macrophage function. J Biomed Biotechnol. 2012; 2012:250464. PMID: 23125524; PMCID: PMC3484331.
    4. Pasillas MP, Shah M, Kamps M. NSD1 PHD domains bind methylated H3K4 and H3K9 using interactions disrupted by point mutations in human sotos syndrome. Hum Mutat. 2011 Mar; 32(3):292-8. PMID: 21972110.
      View in: PubMed
    5. Xu J, Watts JA, Pope SD, Gadue P, Kamps M, Plath K, Zaret KS, Smale ST. Transcriptional competence and the active marking of tissue-specific enhancers by defined transcription factors in embryonic and induced pluripotent stem cells. Genes Dev. 2009 Dec 15; 23(24):2824-38. PMID: 20008934; PMCID: PMC2800090.
    6. Andronicos NM, Chen EI, Baik N, Bai H, Parmer CM, Kiosses WB, Kamps M, Yates JR, Parmer RJ, Miles LA. Proteomics-based discovery of a novel, structurally unique, and developmentally regulated plasminogen receptor, Plg-RKT, a major regulator of cell surface plasminogen activation. Blood. 2010 Feb 18; 115(7):1319-30. PMID: 19897580; PMCID: PMC2826757.
    7. Scheele JS, Kolanczyk M, Gantert M, Zemojtel T, Dorn A, Sykes DB, Sykes DP, Möbest DC, Kamps M, Räpple D, Duchniewicz M. The Spt-Ada-Gcn5-acetyltransferase complex interaction motif of E2a is essential for a subset of transcriptional and oncogenic properties of E2a-Pbx1. Leuk Lymphoma. 2009 May; 50(5):816-28. PMID: 19399691.
      View in: PubMed
    8. Jürgens AS, Kolanczyk M, Moebest DC, Zemojtel T, Lichtenauer U, Duchniewicz M, Gantert MP, Hecht J, Hattenhorst U, Burdach S, Dorn A, Kamps M, Beuschlein F, Räpple D, Scheele JS. PBX1 is dispensable for neural commitment of RA-treated murine ES cells. In Vitro Cell Dev Biol Anim. 2009 May-Jun; 45(5-6):252-63. PMID: 19148706; PMCID: PMC2758398.
    9. Wang GG, Cai L, Pasillas MP, Kamps M. NUP98-NSD1 links H3K36 methylation to Hox-A gene activation and leukaemogenesis. Nat Cell Biol. 2007 Jul; 9(7):804-12. PMID: 17589499.
      View in: PubMed
    10. Odegaard JI, Vats D, Zhang L, Ricardo-Gonzalez R, Smith KL, Sykes DB, Kamps M, Chawla A. Quantitative expansion of ES cell-derived myeloid progenitors capable of differentiating into macrophages. J Leukoc Biol. 2007 Mar; 81(3):711-9. PMID: 17158607; PMCID: PMC1904487.
    11. Lichtenauer UD, Duchniewicz M, Kolanczyk M, Hoeflich A, Hahner S, Else T, Bicknell AB, Zemojtel T, Stallings NR, Schulte DM, Kamps M, Hammer GD, Scheele JS, Beuschlein F. Pre-B-cell transcription factor 1 and steroidogenic factor 1 synergistically regulate adrenocortical growth and steroidogenesis. Endocrinology. 2007 Feb; 148(2):693-704. PMID: 17082260.
      View in: PubMed
    12. Wang GG, Pasillas MP, Kamps M. Persistent transactivation by meis1 replaces hox function in myeloid leukemogenesis models: evidence for co-occupancy of meis1-pbx and hox-pbx complexes on promoters of leukemia-associated genes. Mol Cell Biol. 2006 May; 26(10):3902-16. PMID: 16648484; PMCID: PMC1488994.
    13. Wang GG, Calvo KR, Pasillas MP, Sykes DB, Häcker H, Kamps M. Quantitative production of macrophages or neutrophils ex vivo using conditional Hoxb8. Nat Methods. 2006 Apr; 3(4):287-93. PMID: 16554834.
      View in: PubMed
    14. Häcker H, Redecke V, Blagoev B, Kratchmarova I, Hsu LC, Wang GG, Kamps M, Raz E, Wagner H, Häcker G, Mann M, Karin M. Specificity in Toll-like receptor signalling through distinct effector functions of TRAF3 and TRAF6. Nature. 2006 Jan 12; 439(7073):204-7. PMID: 16306937.
      View in: PubMed
    15. Wang GG, Pasillas MP, Kamps M. Meis1 programs transcription of FLT3 and cancer stem cell character, using a mechanism that requires interaction with Pbx and a novel function of the Meis1 C-terminus. Blood. 2005 Jul 01; 106(1):254-64. PMID: 15755900; PMCID: PMC1895124.
    16. Rave-Harel N, Givens ML, Nelson SB, Duong HA, Coss D, Clark ME, Hall SB, Kamps M, Mellon PL. TALE homeodomain proteins regulate gonadotropin-releasing hormone gene expression independently and via interactions with Oct-1. J Biol Chem. 2004 Jul 16; 279(29):30287-97. PMID: 15138251; PMCID: PMC2935805.
    17. Sykes DB, Kamps M. E2a/Pbx1 induces the rapid proliferation of stem cell factor-dependent murine pro-T cells that cause acute T-lymphoid or myeloid leukemias in mice. Mol Cell Biol. 2004 Feb; 24(3):1256-69. PMID: 14729970; PMCID: PMC321418.
    18. Sykes DB, Scheele J, Pasillas M, Kamps M. Transcriptional profiling during the early differentiation of granulocyte and monocyte progenitors controlled by conditional versions of the E2a-Pbx1 oncoprotein. Leuk Lymphoma. 2003 Jul; 44(7):1187-99. PMID: 12916872.
      View in: PubMed
    19. Sykes DB, Kamps M. Estrogen-regulated conditional oncoproteins: tools to address open questions in normal myeloid cell function, normal myeloid differentiation, and the genetic basis of differentiation arrest in myeloid leukemia. Leuk Lymphoma. 2003 Jul; 44(7):1131-9. PMID: 12916864.
      View in: PubMed
    20. Calvo KR, Sykes DB, Pasillas MP, Kamps M. Nup98-HoxA9 immortalizes myeloid progenitors, enforces expression of Hoxa9, Hoxa7 and Meis1, and alters cytokine-specific responses in a manner similar to that induced by retroviral co-expression of Hoxa9 and Meis1. Oncogene. 2002 Jun 20; 21(27):4247-56. PMID: 12082612.
      View in: PubMed
    21. Klappacher GW, Lunyak VV, Sykes DB, Sawka-Verhelle D, Sage J, Brard G, Ngo SD, Gangadharan D, Jacks T, Kamps M, Rose DW, Rosenfeld MG, Glass CK. An induced Ets repressor complex regulates growth arrest during terminal macrophage differentiation. Cell. 2002 Apr 19; 109(2):169-80. PMID: 12007404.
      View in: PubMed