Michael David
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Title(s) | Professor, Molecular Biology |
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School | Vc-academic Affairs |
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Address | 9500 Gilman Drive # La Jolla CA 92093
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vCard | Download vCard |
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Biography Div. of Cytokine Biology, CBER/FDA | | 06/1996 | Interferons; Cytokines | Univ. of Vienna, Vienna, Austria | Ph.D. | 06/1991 | Pharmacology/Pharmacognosy | Univ. of Vienna, Vienna, Austria | PharmD | 02/1989 | Pharmacy |
National Multiple Sclerosis Society | 2014
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| 2017 | National Multiple Sclerosis Research Award | National Multiple Sclerosis Society | 2007
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| 2010 | National Multiple Sclerosis Research Award | National Multiple Sclerosis Society | 2002
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| 2005 | National Multiple Sclerosis Research Award | Sidney Kimmel Foundation for Cancer Research | 1997
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| 1998 | Sidney Kimmel Scholar Award | NIH | 1993
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| 1996 | Fogarty Scholar Award | Austrian Science Foundation | 1991
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| 1992 | Schroedinger Award |
Overview Research ORNG Applications Bibliographic
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media.
(Note that publications are often cited in additional ways that are not shown here.)
Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication.
Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication.
Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.)
Click a Field or Translation tag to filter the publications.
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Dephosphorylation activates the interferon-stimulated Schlafen family member 11 in the DNA damage response. J Biol Chem. 2019 10 04; 294(40):14674-14685.
Malone D, Lardelli RM, Li M, David M. PMID: 31395656.
View in: PubMed Mentions: 2 Fields: Translation: HumansCells
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DNA damage-induced cell death relies on SLFN11-dependent cleavage of distinct type II tRNAs. Nat Struct Mol Biol. 2018 11; 25(11):1047-1058.
Li M, Kao E, Malone D, Gao X, Wang JYJ, David M. PMID: 30374083.
View in: PubMed Mentions: 13 Fields: Translation: HumansCells
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Non-human Primate Schlafen11 Inhibits Production of Both Host and Viral Proteins. PLoS Pathog. 2016 Dec; 12(12):e1006066.
Stabell AC, Hawkins J, Li M, Gao X, David M, Press WH, Sawyer SL. PMID: 28027315.
View in: PubMed Mentions: 14 Fields: Translation: HumansAnimalsCells
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B-cell survival and development controlled by the coordination of NF-κB family members RelB and cRel. Blood. 2016 Mar 10; 127(10):1276-86.
Almaden JV, Liu YC, Yang E, Otero DC, Birnbaum H, Davis-Turak J, Asagiri M, David M, Goldrath AW, Hoffmann A. PMID: 26773039.
View in: PubMed Mentions: 8 Fields: Translation: AnimalsCells
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IFN-ß Selectively Inhibits IL-2 Production through CREM-Mediated Chromatin Remodeling. J Immunol. 2015 Jun 01; 194(11):5120-8.
Otero DC, Fares-Frederickson NJ, Xiao M, Baker DP, David M. PMID: 25888642.
View in: PubMed Mentions: 2 Fields: Translation: HumansAnimalsCells
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STING contributes to antiglioma immunity via triggering type I IFN signals in the tumor microenvironment. Cancer Immunol Res. 2014 Dec; 2(12):1199-208.
Ohkuri T, Ghosh A, Kosaka A, Zhu J, Ikeura M, David M, Watkins SC, Sarkar SN, Okada H. PMID: 25300859.
View in: PubMed Mentions: 52 Fields: Translation: AnimalsCells
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Unconventional post-translational modifications in immunological signaling. Nat Immunol. 2014 Jun; 15(6):512-20.
Mowen KA, David M. PMID: 24840982.
View in: PubMed Mentions: 26 Fields: Translation: HumansAnimalsCells
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Expression profile of host restriction factors in HIV-1 elite controllers. Retrovirology. 2013 Oct 16; 10:106.
Abdel-Mohsen M, Raposo RA, Deng X, Li M, Liegler T, Sinclair E, Salama MS, Ghanem Hel-D, Hoh R, Wong JK, David M, Nixon DF, Deeks SG, Pillai SK. PMID: 24131498.
View in: PubMed Mentions: 37 Fields: Translation: HumansCells
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IRF7-dependent IFN-ß production in response to RANKL promotes medullary thymic epithelial cell development. J Immunol. 2013 Apr 01; 190(7):3289-98.
Otero DC, Baker DP, David M. PMID: 23440417.
View in: PubMed Mentions: 15 Fields: Translation: AnimalsCells
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Codon-usage-based inhibition of HIV protein synthesis by human schlafen 11. Nature. 2012 Nov 01; 491(7422):125-8.
Li M, Kao E, Gao X, Sandig H, Limmer K, Pavon-Eternod M, Jones TE, Landry S, Pan T, Weitzman MD, David M. PMID: 23000900.
View in: PubMed Mentions: 111 Fields: Translation: HumansCells
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Immunomodulatory functions of type I interferons. Nat Rev Immunol. 2012 Jan 06; 12(2):125-35.
González-Navajas JM, Lee J, David M, Raz E. PMID: 22222875.
View in: PubMed Mentions: 328 Fields: Translation: Humans
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Phospholipase C?-2 and intracellular calcium are required for lipopolysaccharide-induced Toll-like receptor 4 (TLR4) endocytosis and interferon regulatory factor 3 (IRF3) activation. J Biol Chem. 2012 Feb 03; 287(6):3704-9.
Chiang CY, Veckman V, Limmer K, David M. PMID: 22158869.
View in: PubMed Mentions: 36 Fields: Translation: AnimalsCells
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T cell-intrinsic and -extrinsic contributions of the IFNAR/STAT1-axis to thymocyte survival. PLoS One. 2011; 6(9):e24972.
Moro H, Otero DC, Tanabe Y, David M. PMID: 21949815.
View in: PubMed Mentions: 8 Fields: Translation: AnimalsCells
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Interferons and microRNAs. J Interferon Cytokine Res. 2010 Nov; 30(11):825-8.
David M. PMID: 20939680.
View in: PubMed Mentions: 20 Fields: Translation: HumansAnimalsCells
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Onco-miR-155 targets SHIP1 to promote TNFalpha-dependent growth of B cell lymphomas. EMBO Mol Med. 2009 Aug; 1(5):288-95.
Pedersen IM, Otero D, Kao E, Miletic AV, Hother C, Ralfkiaer E, Rickert RC, Gronbaek K, David M. PMID: 19890474.
View in: PubMed Mentions: 73 Fields: Translation: HumansAnimalsCells
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MicroRNAs in the immune response. Cytokine. 2008 Sep; 43(3):391-4.
Pedersen I, David M. PMID: 18701320.
View in: PubMed Mentions: 49 Fields: Translation: HumansAnimals
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Interferon modulation of cellular microRNAs as an antiviral mechanism. Nature. 2007 Oct 18; 449(7164):919-22.
Pedersen IM, Cheng G, Wieland S, Volinia S, Croce CM, Chisari FV, David M. PMID: 17943132.
View in: PubMed Mentions: 358 Fields: Translation: HumansAnimalsCells
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Complement C3d conjugation to anthrax protective antigen promotes a rapid, sustained, and protective antibody response. PLoS One. 2007 Oct 17; 2(10):e1044.
Kolla RV, Chintalapati S, Sabet M, Santelli E, Liddington RC, David M, Fierer J, Guiney D, Rickert RC. PMID: 17940608.
View in: PubMed Mentions: 8 Fields: Translation: AnimalsCells
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Cutting edge: selective tyrosine dephosphorylation of interferon-activated nuclear STAT5 by the VHR phosphatase. J Immunol. 2007 Sep 15; 179(6):3402-6.
Hoyt R, Zhu W, Cerignoli F, Alonso A, Mustelin T, David M. PMID: 17785772.
View in: PubMed Mentions: 25 Fields: Translation: HumansCells
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Cutting edge: inherent and acquired resistance to radiation-induced apoptosis in B cells: a pivotal role for STAT3. J Immunol. 2006 Nov 15; 177(10):6593-7.
Otero DC, Poli V, David M, Rickert RC. PMID: 17082570.
View in: PubMed Mentions: 18 Fields: Translation: AnimalsCells
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Cutting edge: apoptosis-regulating signal kinase 1 is required for reactive oxygen species-mediated activation of IFN regulatory factor 3 by lipopolysaccharide. J Immunol. 2006 May 15; 176(10):5720-4.
Chiang E, Dang O, Anderson K, Matsuzawa A, Ichijo H, David M. PMID: 16670275.
View in: PubMed Mentions: 33 Fields: Translation: HumansAnimalsCells
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Molecular determinants of crosstalk between nuclear receptors and toll-like receptors. Cell. 2005 Sep 09; 122(5):707-21.
Ogawa S, Lozach J, Benner C, Pascual G, Tangirala RK, Westin S, Hoffmann A, Subramaniam S, David M, Rosenfeld MG, Glass CK. PMID: 16143103.
View in: PubMed Mentions: 229 Fields: Translation: AnimalsCells
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Cutting edge: role of STAT1, STAT3, and STAT5 in IFN-alpha beta responses in T lymphocytes. J Immunol. 2005 Jan 15; 174(2):609-13.
Tanabe Y, Nishibori T, Su L, Arduini RM, Baker DP, David M. PMID: 15634877.
View in: PubMed Mentions: 52 Fields: Translation: AnimalsCells
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Induction of IFN-regulated factors and antitumoral surveillance by transfected placebo plasmid DNA. Mol Ther. 2005 Jan; 11(1):112-9.
Li S, Wilkinson M, Xia X, David M, Xu L, Purkel-Sutton A, Bhardwaj A. PMID: 15585412.
View in: PubMed Mentions: 12 Fields: Translation: AnimalsCells
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Arginine methylation of NIP45 modulates cytokine gene expression in effector T lymphocytes. Mol Cell. 2004 Aug 27; 15(4):559-71.
Mowen KA, Schurter BT, Fathman JW, David M, Glimcher LH. PMID: 15327772.
View in: PubMed Mentions: 51 Fields: Translation: HumansAnimalsCells
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Inhibition of lipopolysaccharide-induced interferon regulatory factor 3 activation and protection from septic shock by hydroxystilbenes. Shock. 2004 May; 21(5):470-5.
Dang O, Navarro L, David M. PMID: 15087825.
View in: PubMed Mentions: 9 Fields: Translation: HumansAnimalsCells
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Arsenic inhibition of the JAK-STAT pathway. Oncogene. 2004 Apr 29; 23(20):3603-12.
Cheng HY, Li P, David M, Smithgall TE, Feng L, Lieberman MW. PMID: 15116095.
View in: PubMed Mentions: 19 Fields: Translation: HumansCells
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Arginine methylation of RNA helicase a determines its subcellular localization. J Biol Chem. 2004 May 28; 279(22):22795-8.
Smith WA, Schurter BT, Wong-Staal F, David M. PMID: 15084609.
View in: PubMed Mentions: 35 Fields: Translation: HumansCells
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Cutting edge: anthrax lethal toxin inhibits activation of IFN-regulatory factor 3 by lipopolysaccharide. J Immunol. 2004 Jan 15; 172(2):747-51.
Dang O, Navarro L, Anderson K, David M. PMID: 14707042.
View in: PubMed Mentions: 24 Fields: Translation: HumansAnimalsCells
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Impaired development of CD4+ CD25+ regulatory T cells in the absence of STAT1: increased susceptibility to autoimmune disease. J Exp Med. 2004 Jan 05; 199(1):25-34.
Nishibori T, Tanabe Y, Su L, David M. PMID: 14699080.
View in: PubMed Mentions: 45 Fields: Translation: AnimalsCells
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The Epstein-Barr virus SM protein induces STAT1 and interferon-stimulated gene expression. J Virol. 2003 Mar; 77(6):3690-701.
Ruvolo V, Navarro L, Sample CE, David M, Sung S, Swaminathan S. PMID: 12610144.
View in: PubMed Mentions: 18 Fields: Translation: HumansCells
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Signal transduction by type I interferons. Biotechniques. 2002 Oct; Suppl:58-65.
David M. PMID: 12395928.
View in: PubMed Mentions: 14 Fields: Translation: HumansAnimalsCells
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Arginine methylation of STAT1 regulates its dephosphorylation by T cell protein tyrosine phosphatase. J Biol Chem. 2002 Sep 27; 277(39):35787-90.
Zhu W, Mustelin T, David M. PMID: 12171910.
View in: PubMed Mentions: 27 Fields: Translation: HumansAnimalsCells
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Identification of a nuclear Stat1 protein tyrosine phosphatase. Mol Cell Biol. 2002 Aug; 22(16):5662-8.
ten Hoeve J, de Jesus Ibarra-Sanchez M, Fu Y, Zhu W, Tremblay M, David M, Shuai K. PMID: 12138178.
View in: PubMed Mentions: 155 Fields: Translation: HumansAnimalsCells
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Regulation of STAT protein synthesis by c-Cbl. Oncogene. 2001 Nov 01; 20(50):7326-33.
Blesofsky WA, Mowen K, Arduini RM, Baker DP, Murphy MA, Bowtell DD, David M. PMID: 11704862.
View in: PubMed Mentions: 4 Fields: Translation: AnimalsCells
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Analysis of protein arginine methylation and protein arginine-methyltransferase activity. Sci STKE. 2001 Jul 31; 2001(93):pl1.
Mowen KA, David M. PMID: 11752667.
View in: PubMed Mentions: Fields: Translation: HumansAnimalsCells
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Arginine methylation of STAT1 modulates IFNalpha/beta-induced transcription. Cell. 2001 Mar 09; 104(5):731-41.
Mowen KA, Tang J, Zhu W, Schurter BT, Shuai K, Herschman HR, David M. PMID: 11257227.
View in: PubMed Mentions: 125 Fields: Translation: HumansCells
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Cytokine activation of transcription. Genet Eng (N Y). 2001; 23:35-44.
Mowen KA, David M. PMID: 11570105.
View in: PubMed Mentions: Fields: Translation: Cells
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Regulation of STAT1 nuclear export by Jak1. Mol Cell Biol. 2000 Oct; 20(19):7273-81.
Mowen K, David M. PMID: 10982844.
View in: PubMed Mentions: 24 Fields: Translation: HumansCells
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Distinct mechanisms of STAT phosphorylation via the interferon-alpha/beta receptor. Selective inhibition of STAT3 and STAT5 by piceatannol. J Biol Chem. 2000 Apr 28; 275(17):12661-6.
Su L, David M. PMID: 10777558.
View in: PubMed Mentions: 27 Fields: Translation: HumansCells
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p38-dependent activation of interferon regulatory factor 3 by lipopolysaccharide. J Biol Chem. 1999 Dec 10; 274(50):35535-8.
Navarro L, David M. PMID: 10585427.
View in: PubMed Mentions: 31 Fields: Translation: HumansCells
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Rapid STAT phosphorylation via the B cell receptor. Modulatory role of CD19. J Biol Chem. 1999 Nov 05; 274(45):31770-4.
Su L, Rickert RC, David M. PMID: 10542198.
View in: PubMed Mentions: 15 Fields: Translation: HumansCells
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Inhibition of B cell receptor-mediated apoptosis by IFN. J Immunol. 1999 Jun 01; 162(11):6317-21.
Su L, David M. PMID: 10352242.
View in: PubMed Mentions: 18 Fields: Translation: HumansCells
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Role of the STAT1-SH2 domain and STAT2 in the activation and nuclear translocation of STAT1. J Biol Chem. 1998 Nov 13; 273(46):30073-6.
Mowen K, David M. PMID: 9804758.
View in: PubMed Mentions: 16 Fields: Translation: AnimalsCells
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Cytomegalovirus activates interferon immediate-early response gene expression and an interferon regulatory factor 3-containing interferon-stimulated response element-binding complex. Mol Cell Biol. 1998 Jul; 18(7):3796-802.
Navarro L, Mowen K, Rodems S, Weaver B, Reich N, Spector D, David M. PMID: 9632763.
View in: PubMed Mentions: 68 Fields: Translation: HumansCells
This graph shows the total number of publications by year. To see the data as text, click here.
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Year | Publications |
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1998 | 2 | 1999 | 3 | 2000 | 2 | 2001 | 4 | 2002 | 3 | 2003 | 2 | 2004 | 5 | 2005 | 3 | 2006 | 2 | 2007 | 3 | 2008 | 1 | 2009 | 1 | 2010 | 1 | 2011 | 2 | 2012 | 2 | 2013 | 2 | 2014 | 2 | 2015 | 1 | 2016 | 2 | 2018 | 1 | 2019 | 1 |
This graph shows the number and percent of publications by field.
Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications.
Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written.
To see the data as text, click here.
This graph shows the number and percent of publications by field.
Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications.
Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written.
To see the data as text, click here.
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