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Kun-Liang Guan

Title(s)Professor, Pharmacology
SchoolHealth Sciences
Address9500 Gilman Drive #0695
La Jolla CA 92093
Phone858-822-7945
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    Collapse Biography 
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    Ph.D.Purdue University

    Collapse Overview 

    Collapse Research 
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    Molecular Mechanism and Therapy for Ocular Melanoma
    NIH/NCI R01CA217642Mar 14, 2017 - Feb 28, 2022
    Role: Co-Principal Investigator
    The mTOR and Hippo pathway in cell growth and cancer
    NIH/NCI R35CA196878Aug 5, 2015 - Jul 31, 2022
    Role: Principal Investigator
    Regulation of the Hippo pathway and its role in uveal melanoma
    NIH/NEI R01EY022611Sep 1, 2012 - Aug 31, 2016
    Role: Principal Investigator
    Regulation and function of the YAP transcription co-activator oncoprotein
    NIH/NCI R01CA132809Apr 8, 2008 - Feb 28, 2018
    Role: Principal Investigator
    Rag GTPases in mTOR regulation and physiological functions
    NIH/NCI R01CA108941Sep 3, 2004 - Sep 30, 2007
    Role: Principal Investigator
    S6K and mTOR as targets for tuberous sclerosis
    NIH/NCI R41CA101611Jul 1, 2003 - Jun 30, 2004
    Role: Principal Investigator
    Regulation of Ras and Rheb modification by GCN2
    NIH/NIGMS R01GM062694Jul 1, 2000 - Sep 30, 2007
    Role: Principal Investigator
    REGULATION OF PROTEIN TYROSINE PHOSPHORYLATION IN YEAST
    NIH/NIGMS R01GM055642May 1, 1997 - Apr 30, 2001
    Role: Principal Investigator
    Protein phosphorylation and growth factor function
    NIH/NIGMS R01GM051586Aug 1, 1994 - Sep 30, 2007
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. The Hippo Pathway: Biology and Pathophysiology. Annu Rev Biochem. 2019 06 20; 88:577-604. Ma S, Meng Z, Chen R, Guan KL. PMID: 30566373.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    2. Hippo pathway regulation of gastrointestinal tissues. Annu Rev Physiol. 2015; 77:201-27. Yu FX, Meng Z, Plouffe SW, Guan KL. PMID: 25293527.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    3. An emerging role for TOR signaling in mammalian tissue and stem cell physiology. Development. 2011 Aug; 138(16):3343-56. Russell RC, Fang C, Guan KL. PMID: 21791526.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansAnimalsCells
    4. Amino acid signaling in TOR activation. Annu Rev Biochem. 2011; 80:1001-32. Kim J, Guan KL. PMID: 21548787.
      View in: PubMed   Mentions: 81     Fields:    Translation:HumansAnimalsCells
    5. Generation of acetyllysine antibodies and affinity enrichment of acetylated peptides. Nat Protoc. 2010 Sep; 5(9):1583-95. Guan KL, Yu W, Lin Y, Xiong Y, Zhao S. PMID: 21085124.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansCells
    6. Critical roles for the TSC-mTOR pathway in ß-cell function. Am J Physiol Endocrinol Metab. 2009 Nov; 297(5):E1013-22. Mori H, Inoki K, Opland D, Münzberg H, Villanueva EC, Faouzi M, Ikenoue T, Kwiatkowski DJ, Macdougald OA, Myers MG, Guan KL. PMID: 19690069.
      View in: PubMed   Mentions: 41     Fields:    Translation:AnimalsCells
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