Ronald Ellis

Title(s)Professor In Residence, Neurosciences
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Collapse Biography 
    Collapse Education and Training
    Williams College, Williamstown, MABA05/1982Psychology
    UC San Diego, San Diego, CA11/2018Senior Faculty Mentor Training
    Boston University, Boston, MAMD, PhD06/1989Medicine, Behavioral Neuroscience
    Collapse Awards and Honors
    UC San Diego2009Arnold P. Gold Foundation Leonard Tow Humanism in Medicine Award. UC San Diego School of Medicine
    UC San Diego1997  - 2001Neurosciences Junior Faculty Teaching Award

    Collapse Overview 
    Collapse Overview
    Dr. Ellis’s clinical work and research are focused on the neurological manifestations of HIV infection and their pathogenesis and treatment, particularly dementia, neurocognitive disorders and sensory polyneuropathy. He is Associate Director of the NIMH-funded P03 HIV Neurobehavioral Research Programs (HNRP) and PI of its NeuroAssessment Core, which comprises a Clinical Research Support Unit (CRSU) and a Laboratory, Pharmacology and Biomarker Unit (LPBU). He also serves as an investigator in the Translational Methamphetamine AIDS Research Center (TMARC) and the Center for Medicinal Cannabis Research (CMCR). TMARC comprises an integrated program of human clinical, neuroimaging, laboratory and animal model investigations being conducted at UCSD, The Sanford-Burnham Institute, and the Scripps Institute. Dr. Ellis is Chair of the Neurology Collaborative Science Group of the AIDS Clinical Trials Group (ACTG).

    Collapse Research 
    Collapse Research Activities and Funding
    Immunometabolicgene expression profiles associated with depressed mood and behavioral domains inpeople with HIV
    NIH R01MH128869Sep 15, 2021 - Jun 30, 2026
    Role: Principal Investigator
    Biopsychosocial Phenotypes and Potential Mechanisms in CHARTER
    NIH R01MH125720Dec 8, 2020 - Oct 31, 2025
    Role: Co-Principal Investigator
    Effect of Cannabis Administration and Endocannabinoids on HIV Neuropathic Pain
    NIH R01DA043430Feb 1, 2017 - Dec 31, 2020
    Role: Principal Investigator
    Phase II trial of tesamorelin for cognition in aging HIV-infected persons
    NIH R01AG048650Sep 30, 2015 - May 31, 2021
    Role: Principal Investigator
    A Novel FMRI Biomarker of Asymptomatic HIV-Associated Neurocognitive Disorders
    NIH R01MH108466Jul 1, 2015 - Apr 30, 2020
    Role: Co-Investigator
    Building research capacity in aging HIV-infected persons
    NIH R03AG044910Sep 30, 2013 - Jul 31, 2015
    Role: Principal Investigator
    California NeuroAIDS Tissue Network
    NIH U24MH100928May 1, 2013 - Feb 28, 2023
    Role: Co-Investigator
    Intrahost HIV population dynamics in CNS and other tissues
    NIH R01MH101012May 1, 2013 - Jan 31, 2016
    Role: Principal Investigator
    HIV Clade on Cognitive and Neurological Disorders Brazil
    NIH R21MH076651Jan 25, 2006 - Dec 31, 2009
    Role: Principal Investigator
    HIV Neurobehavioral Research Center
    NIH P30MH062512Apr 24, 2001 - Jan 31, 2026
    Role: Co-Investigator
    NEUROAIDS: EFFECTS OF METHAMPHETAMINE AND HCV
    NIH P01DA012065Jul 1, 1999 - Apr 30, 2011
    Role: Co-Investigator
    HIV Neurocognitive Disorders: A Randomized Clinical Trial of CNS-Targeted HAART
    NIH R01MH058076Sep 30, 1997 - Jul 31, 2012
    Role: Principal Investigator
    CEREBRAL LATERALITY IN AGING ALCOHOLICS
    NIH F31AA005260Mar 1, 1987
    Role: Principal Investigator
    General Clinical Research Center
    NIH M01RR000827Mar 1, 1974 - Nov 30, 2010
    Role: Co-Investigator

    Collapse ORNG Applications 
    Collapse Clinical Trials
    Collapse Featured Publications
    Collapse Faculty Mentoring

    Collapse Featured Content 
    Collapse Featured Videos

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Cognitive and Physiologic Reserve Independently Relate to Superior Neurocognitive Abilities in Adults Aging With HIV. J Acquir Immune Defic Syndr. 2022 08 01; 90(4):440-448. Saloner R, Lobo JD, Paolillo EW, Campbell LM, Letendre SL, Cherner M, Grant I, Heaton RK, Ellis RJ, Moore DJ, CHARTER Study Group. PMID: 35364601; PMCID: PMC9246889.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    2. Association of Plasma Eicosanoid Levels With Immune, Viral, and Cognitive Outcomes in People With HIV. Neurology. 2022 Jul 18. Deme P, Moniruzzaman M, Moore D, Heaton R, Ellis R, Letendre S, Haughey N. PMID: 35851253.
      View in: PubMed   Mentions:    Fields:    
    3. Neuropathic pain correlates with worsening cognition in people with human immunodeficiency virus. Brain. 2022 06 30; 145(6):2206-2213. Ellis RJ, Sacktor N, Clifford DB, Marra CM, Collier AC, Gelman B, Robinson-Papp J, Letendre SL, Heaton RK, CNS Antiretroviral Therapy Effects Research (CHARTER) Study Group. PMID: 35773234; PMCID: PMC9630658.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    4. Longitudinal evaluation of neurologic-post acute sequelae SARS-CoV-2 infection symptoms. Ann Clin Transl Neurol. 2022 07; 9(7):995-1010. Shanley JE, Valenciano AF, Timmons G, Miner AE, Kakarla V, Rempe T, Yang JH, Gooding A, Norman MA, Banks SJ, Ritter ML, Ellis RJ, Horton L, Graves JS. PMID: 35702954; PMCID: PMC9268882.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    5. Higher cerebrospinal fluid biomarkers of neuronal injury in HIV-associated neurocognitive impairment. J Neurovirol. 2022 Jun; 28(3):438-445. Ellis RJ, Chenna A, Petropoulos CJ, Lie Y, Curanovic D, Crescini M, Winslow J, Sundermann E, Tang B, Letendre SL. PMID: 35674935; PMCID: PMC9470698.
      View in: PubMed   Mentions:    Fields:    
    6. Cingulate transcranial direct current stimulation in adults with HIV. PLoS One. 2022; 17(6):e0269491. Jiang X, Dahmani S, Bronshteyn M, Yang FN, Ryan JP, Gallagher RC, Damera SR, Kumar PN, Moore DJ, Ellis RJ, Turkeltaub PE. PMID: 35658059; PMCID: PMC9165807.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    7. Toward Composite Pain Biomarkers of Neuropathic Pain-Focus on Peripheral Neuropathic Pain. Front Pain Res (Lausanne). 2022; 3:869215. Diaz MM, Caylor J, Strigo I, Lerman I, Henry B, Lopez E, Wallace MS, Ellis RJ, Simmons AN, Keltner JR. PMID: 35634449; PMCID: PMC9130475.
      View in: PubMed   Mentions:
    8. Association Between VACS Index and Health-Related Quality of Life in Persons with HIV: Moderating Role of Fruit and Vegetable Consumption. Int J Behav Med. 2022 May 09. Campbell LM, Montoya JL, Fazeli PL, Marquine MJ, Ellis RJ, Jeste DV, Moore DJ, Moore RC. PMID: 35534722.
      View in: PubMed   Mentions:    Fields:    
    9. Ethnic/Racial Disparities in Longitudinal Neurocognitive Decline in People With HIV. J Acquir Immune Defic Syndr. 2022 05 01; 90(1):97-105. Wei-Ming Watson C, Kamalyan L, Tang B, Hussain MA, Cherner M, Rivera Mindt M, Byrd DA, Franklin DR, Collier AC, Clifford DB, Gelman B, Morgello S, McCutchan JA, Ellis RJ, Grant I, Heaton RK, Marquine MJ, CHARTER Group. PMID: 35081558; PMCID: PMC8986565.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    10. Higher Cerebrospinal Fluid Soluble Urokinase-type Plasminogen Activator Receptor, But Not Interferon γ-inducible Protein 10, Correlate With Higher Working Memory Deficits. J Acquir Immune Defic Syndr. 2022 05 01; 90(1):106-114. De Almeida SM, Rotta I, Tang B, Umlauf A, Vaida F, Cherner M, Franklin D, Letendre S, Ellis RJ, HNRC Group. PMID: 35090158; PMCID: PMC8986587.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    11. Higher Comorbidity Burden Predicts Worsening Neurocognitive Trajectories in People with Human Immunodeficiency Virus. Clin Infect Dis. 2022 04 28; 74(8):1323-1328. Ellis RJ, Paolillo E, Saloner R, Heaton RK. PMID: 34329400; PMCID: PMC9049252.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    12. Soluble CD14 is subtype-dependent in serum but not in cerebrospinal fluid in people with HIV. J Neuroimmunol. 2022 05 15; 366:577845. de Almeida SM, Tang B, Vaida F, Letendre S, Ellis RJ, HNRC Group. PMID: 35313166.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    13. Peripheral inflammation and depressed mood independently predict neurocognitive worsening over 12 years. Brain Behav Immun Health. 2022 May; 21:100437. Tang B, Collier AC, Morgello S, Cookson D, Sacktor N, Ellis RJ, Marra CM, Clifford DB, Gelman BB, Robinson-Papp J, McCutchan JA, Letendre S, Heaton RK, Grant I. PMID: 35308084; PMCID: PMC8928134.
      View in: PubMed   Mentions:
    14. Main lymphocyte subpopulations in cerebrospinal fluid and peripheral blood in HIV-1 subtypes C and B. J Neurovirol. 2022 04; 28(2):291-304. de Almeida SM, Beltrame MP, Tang B, Rotta I, Schluga Y, Justus JLP, da Rocha MT, Abramson I, Vaida F, Schrier R, Ellis RJ. PMID: 35190973.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    15. Higher buccal mitochondrial DNA and mitochondrial common deletion number are associated with markers of neurodegeneration and inflammation in cerebrospinal fluid. J Neurovirol. 2022 04; 28(2):281-290. Solanky D, Fields JA, Iudicello JE, Ellis RJ, Franklin D, Clifford DB, Gelman BB, Marra CM, Morgello S, Rubin LH, Grant I, Heaton RK, Letendre SL, Mehta SR. PMID: 35157246; PMCID: PMC9352370.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    16. CSF markers of AD-related pathology relate specifically to memory impairment in older people with HIV: a pilot study. J Neurovirol. 2022 02; 28(1):162-167. Lobo JD, Moore DJ, Bondi MW, Soontornniyomkij V, Soontornniyomkij B, Gouaux B, Achim CL, Ellis RJ, Sundermann EE. PMID: 35103880; PMCID: PMC9081235.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    17. The impacts of HIV infection, age, and education on functional brain networks in adults with HIV. J Neurovirol. 2022 04; 28(2):265-273. Yang FN, Hassanzadeh-Behbahani S, Kumar P, Moore DJ, Ellis RJ, Jiang X. PMID: 35044643.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    18. Polygenic networks in peripheral leukocytes indicate patterns associated with HIV infection and context-dependent effects of cannabis use. Brain Behav Immun Health. 2022 Mar; 20:100414. Basova LV, Lukkes SE, Milner R, Ellis RJ, Cherner M, Iudicello J, Marcondes MCG. PMID: 35128491; PMCID: PMC8808072.
      View in: PubMed   Mentions:
    19. Fatigue is associated with worse cognitive and everyday functioning in older persons with HIV. AIDS. 2022 05 01; 36(6):763-772. Campbell LM, Sun-Suslow N, Heaton A, Heaton RK, Ellis RJ, Moore DJ, Moore RC. PMID: 34999606; PMCID: PMC9081180.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    20. A Haptoglobin Exon Copy Number Variant Associates With HIV-Associated Neurocognitive Impairment in European and African-Descent Populations. Front Genet. 2021; 12:756685. Bai H, Kaur H, Kallianpur AR, Hulgan T, Franklin DR, Letendre SL, Ellis RJ, Bush WS. PMID: 35003209; PMCID: PMC8727522.
      View in: PubMed   Mentions:
    21. Frailty Syndrome Is Associated with Poorer Self-Reported Sleep Quality Among Older Persons with Human Immunodeficiency Virus. AIDS Res Hum Retroviruses. 2022 02; 38(2):87-96. Sun-Suslow N, Balon E, Montoya JL, Saloner R, Campbell LM, Serrano V, Ellis RJ, Moore DJ. PMID: 34779233; PMCID: PMC8861916.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    22. Prior Methamphetamine Use Disorder History Does Not Impair Interoceptive Processing of Soft Touch in HIV Infection. Viruses. 2021 12 10; 13(12). Bischoff-Grethe A, Ellis RJ, Tapert SF, Paulus MP, Grant I. PMID: 34960745; PMCID: PMC8705776.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    23. Identification of Youthful Neurocognitive Trajectories in Adults Aging with HIV: A Latent Growth Mixture Model. AIDS Behav. 2022 Jun; 26(6):1966-1979. Saloner R, Lobo JD, Paolillo EW, Campbell LM, Letendre SL, Cherner M, Grant I, Heaton RK, Ellis RJ, Roesch SC, Moore DJ, CHARTER Study Group. PMID: 34878634; PMCID: PMC9046348.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    24. Polypharmacy in older adults with HIV infection: Effects on the brain. J Am Geriatr Soc. 2022 03; 70(3):924-927. Smith L, Letendre S, Erlandson KM, Ma Q, Ellis RJ, Farhadian SF. PMID: 34855982; PMCID: PMC8904273.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    25. Association of painful human immunodeficiency virus distal sensory polyneuropathy with aberrant expectation of pain relief: functional magnetic resonance imaging evidence. Brain Commun. 2021; 3(4):fcab260. Strigo IA, Keltner JR, Ellis RJ, Simmons AN. PMID: 34859214; PMCID: PMC8633742.
      View in: PubMed   Mentions: 2  
    26. Markers of Gut Barrier Function and Microbial Translocation Associate with Lower Gut Microbial Diversity in People with HIV. Viruses. 2021 09 22; 13(10). Ellis RJ, Iudicello JE, Heaton RK, Isnard S, Lin J, Routy JP, Gianella S, Hoenigl M, Knight R. PMID: 34696320; PMCID: PMC8537977.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    27. Current Considerations for Clinical Management and Care of People with HIV: Findings from the 11th Annual International HIV and Aging Workshop. AIDS Res Hum Retroviruses. 2021 11; 37(11):807-820. Kamkwalala AR, Garg A, Roy U, Matthews A, Castillo-Mancilla J, Lake JE, Sebastiani G, Yin M, Brown TT, Kamer AR, Jabs DA, Ellis RJ, Boffito M, Greene M, Schmalzle S, Siegler E, Erlandson KM, Moore DJ. PMID: 34405689; PMCID: PMC8817696.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    28. Reduced Gut Microbiome Diversity in People With HIV Who Have Distal Neuropathic Pain. J Pain. 2022 02; 23(2):318-325. Ellis RJ, Heaton RK, Gianella S, Rahman G, Knight R. PMID: 34530155.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    29. Baseline Neurocognitive Impairment (NCI) Is Associated With Incident Frailty but Baseline Frailty Does Not Predict Incident NCI in Older Persons With Human Immunodeficiency Virus (HIV). Clin Infect Dis. 2021 08 16; 73(4):680-688. Masters MC, Perez J, Wu K, Ellis RJ, Goodkin K, Koletar SL, Andrade A, Yang J, Brown TT, Palella FJ, Sacktor N, Tassiopoulos K, Erlandson KM. PMID: 34398957; PMCID: PMC8499706.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    30. Low-Level HIV RNA in Cerebrospinal Fluid and Neurocognitive Performance: A Longitudinal Cohort Study. J Acquir Immune Defic Syndr. 2021 08 15; 87(5):1196-1204. Anderson AM, Tang B, Vaida F, Mcclernon D, Deutsch R, Cherner M, Cookson D, Crescini M, Grant I, Ellis RJ, Letendre SL. PMID: 33901102; PMCID: PMC8596378.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    31. Paresthesia Predicts Increased Risk of Distal Neuropathic Pain in Older People with HIV-Associated Sensory Polyneuropathy. Pain Med. 2021 08 06; 22(8):1850-1856. Diaz MM, Keltner JR, Simmons AN, Franklin D, Moore RC, Clifford D, Collier AC, Gelman BB, Marra PDC, McCutchan JA, Morgello S, Sacktor N, Best B, Notestine CF, Weibel SG, Grant I, Marcotte TD, Vaida F, Letendre S, Heaton R, Ellis RJ. PMID: 33565583; PMCID: PMC8502467.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    32. Plasma Citrate and Succinate Are Associated With Neurocognitive Impairment in Older People With HIV. Clin Infect Dis. 2021 08 02; 73(3):e765-e772. Hileman CO, Kalayjian RC, Azzam S, Schlatzer D, Wu K, Tassiopoulos K, Bedimo R, Ellis RJ, Erlandson KM, Kallianpur A, Koletar SL, Landay AL, Palella FJ, Taiwo B, Pallaki M, Hoppel CL. PMID: 33564870; PMCID: PMC8326582.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    33. Cannabis and Inflammation in HIV: A Review of Human and Animal Studies. Viruses. 2021 08 02; 13(8). Ellis RJ, Wilson N, Peterson S. PMID: 34452386; PMCID: PMC8402692.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    34. Alterations of Brain Metabolites in Adults With HIV: A Systematic Meta-analysis of Magnetic Resonance Spectroscopy Studies. Neurology. 2021 09 14; 97(11):e1085-e1096. Dahmani S, Kaliss N, VanMeter JW, Moore DJ, Ellis RJ, Jiang X. PMID: 34253633; PMCID: PMC8456358.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    35. The Relationships between HIV-1 Infection, History of Methamphetamine Use Disorder, and Soluble Biomarkers in Blood and Cerebrospinal Fluid. Viruses. 2021 07 01; 13(7). Walter TJ, Iudicello J, Cookson DR, Franklin D, Tang B, Young JW, Perry W, Ellis R, Heaton RK, Grant I, Minassian A, Letendre S. PMID: 34372493; PMCID: PMC8310127.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    36. Daily Cannabis Use is Associated With Lower CNS Inflammation in People With HIV. J Int Neuropsychol Soc. 2021 07; 27(6):661-672. Watson CW, Campbell LM, Sun-Suslow N, Hong S, Umlauf A, Ellis RJ, Iudicello JE, Letendre S, Marcotte TD, Heaton RK, Morgan EE, Grant I. PMID: 34261550; PMCID: PMC8288448.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    37. Beneficial Effects of Cannabis on Blood-Brain Barrier Function in Human Immunodeficiency Virus. Clin Infect Dis. 2021 07 01; 73(1):124-129. Ellis RJ, Peterson S, Cherner M, Morgan E, Schrier R, Tang B, Hoenigl M, Letendre S, Iudicello J. PMID: 32296832; PMCID: PMC8246839.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    38. Higher CSF Ferritin Heavy-Chain (Fth1) and Transferrin Predict Better Neurocognitive Performance in People with HIV. Mol Neurobiol. 2021 Oct; 58(10):4842-4855. Kaur H, Bush WS, Letendre SL, Ellis RJ, Heaton RK, Patton SM, Connor JR, Samuels DC, Franklin DR, Hulgan T, Kallianpur AR. PMID: 34195939; PMCID: PMC9236615.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    39. Characterization of HIV-Associated Neurocognitive Impairment in Middle-Aged and Older Persons With HIV in Lima, Peru. Front Neurol. 2021; 12:629257. Diaz MM, Zacarías MG, Sotolongo P, Sanes MF, Franklin DJ, Marquine MJ, Cherner M, Cárcamo C, Ellis RJ, Lanata S, García PJ. PMID: 34220665; PMCID: PMC8248346.
      View in: PubMed   Mentions: 1  
    40. Prevention of HIV-1 TAT Protein-Induced Peripheral Neuropathy and Mitochondrial Disruption by the Antimuscarinic Pirenzepine. Front Neurol. 2021; 12:663373. Han MM, Frizzi KE, Ellis RJ, Calcutt NA, Fields JA. PMID: 34211430; PMCID: PMC8239242.
      View in: PubMed   Mentions: 2  
    41. Mitochondrial DNA haplogroups and domain-specific neurocognitive performance in adults with HIV. J Neurovirol. 2021 08; 27(4):557-567. Volpe K, Samuels D, Kallianpur A, Ellis R, Franklin D, Letendre S, Heaton RK, Hulgan T. PMID: 34101088; PMCID: PMC8527871.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    42. Depression is associated with hippocampal volume loss in adults with HIV. Hum Brain Mapp. 2021 08 15; 42(12):3750-3759. Bronshteyn M, Yang FN, Shattuck KF, Dawson M, Kumar P, Moore DJ, Ellis RJ, Jiang X. PMID: 34089276; PMCID: PMC8288081.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    43. Low Neuroactive Steroids Identifies a Biological Subtype of Depression in Adults with Human Immunodeficiency Virus on Suppressive Antiretroviral Therapy. J Infect Dis. 2021 05 20; 223(9):1601-1611. Mukerji SS, Misra V, Lorenz DR, Chettimada S, Keller K, Letendre S, Ellis RJ, Morgello S, Parker RA, Gabuzda D. PMID: 32157292; PMCID: PMC8136979.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    44. Large Mitochondrial DNA Deletions in HIV Sensory Neuropathy. Neurology. 2021 07 13; 97(2):e156-e165. Roda RH, Bargiela D, Chen W, Perry K, Ellis RJ, Clifford DB, Bharti A, Kallianpur AR, Oliveira MF, Diaz MM, Rubin LH, Gavegnano C, McArthur JC, Hoke A, Polydefkis M. PMID: 33947785; PMCID: PMC8279564.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCTClinical Trials
    45. Connectome-based prediction of global cognitive performance in people with HIV. Neuroimage Clin. 2021; 30:102677. Yang FN, Hassanzadeh-Behbahani S, Bronshteyn M, Dawson M, Kumar P, Moore DJ, Ellis RJ, Jiang X. PMID: 34215148; PMCID: PMC8102633.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    46. Cannabis and the Gut-Brain Axis Communication in HIV Infection. Cannabis Cannabinoid Res. 2021 04; 6(2):92-104. Wilson NL, Peterson SN, Ellis RJ. PMID: 33912676; PMCID: PMC8064951.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    47. Social Isolation Is Linked to Inflammation in Aging People With HIV and Uninfected Individuals. J Acquir Immune Defic Syndr. 2021 04 15; 86(5):600-606. Ellis RJ, Iudicello J, Sun-Suslow N, Grelotti D, Cherner M, Morgan E, Letendre SL, Heaton RK. PMID: 33298794; PMCID: PMC7933098.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    48. Low CD4+ cell count nadir exacerbates the impacts of APOE ε4 on functional connectivity and memory in adults with HIV. AIDS. 2021 04 01; 35(5):727-736. Yang FN, Bronshteyn M, Flowers SA, Dawson M, Kumar P, Rebeck GW, Turner RS, Moore DJ, Ellis RJ, Jiang X. PMID: 33587445; PMCID: PMC8318747.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    49. Detection of H3K4me3 Identifies NeuroHIV Signatures, Genomic Effects of Methamphetamine and Addiction Pathways in Postmortem HIV+ Brain Specimens that Are Not Amenable to Transcriptome Analysis. Viruses. 2021 03 24; 13(4). Basova L, Lindsey A, McGovern AM, Ellis RJ, Marcondes MCG. PMID: 33805201; PMCID: PMC8064323.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    50. IgG intrathecal synthesis in HIV-associated neurocognitive disorder (HAND) according to the HIV-1 subtypes and pattern of HIV RNA in CNS and plasma compartments. J Neuroimmunol. 2021 06 15; 355:577542. De Almeida SM, Rotta I, Tang B, Vaida F, Letendre S, Ellis RJ, HNRC Group. PMID: 33845284; PMCID: PMC8102367.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    51. Gut microbiota dysbiosis is associated with worse emotional states in HIV infection. J Neurovirol. 2021 04; 27(2):228-238. Pérez-Santiago J, Marquine MJ, Cookson D, Giraud-Colón R, Heaton RK, Grant I, Ellis RJ, Letendre SL, Peterson SN. PMID: 33651324; PMCID: PMC8781727.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    52. Telomere length is associated with HIV infection, methamphetamine use, inflammation, and comorbid disease risk. Drug Alcohol Depend. 2021 04 01; 221:108639. Mehta SR, Iudicello JE, Lin J, Ellis RJ, Morgan E, Okwuegbuna O, Cookson D, Karris M, Saloner R, Heaton R, Grant I, Letendre S, TMARC Group. PMID: 33621803; PMCID: PMC8026664.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    53. Cannabis use is not associated with increased balance disturbances in HIV-infected individuals. J Cannabis Res. 2021 Feb 03; 3(1):3. Kiendrebeogo P, Grelotti D, Cherner M, Moore RC, Tang B, Ellis RJ. PMID: 33536072; PMCID: PMC7860021.
      View in: PubMed   Mentions:
    54. Cerebrospinal fluid CXCL10 is associated with the presence of low level CSF HIV during suppressive antiretroviral therapy. J Neuroimmunol. 2021 04 15; 353:577493. Anderson AM, Kundu S, Tang B, Vaida F, Okwuegbuna O, McClernon D, Cherner M, Deutsch R, Cookson D, Crescini M, Grant I, Zetterberg H, Blennow K, Gisslen M, Ellis RJ, Letendre SL. PMID: 33571816; PMCID: PMC8634543.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
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    290. Two-year prospective study of major depressive disorder in HIV-infected men. J Affect Disord. 2008 Jun; 108(3):225-34. Atkinson JH, Heaton RK, Patterson TL, Wolfson T, Deutsch R, Brown SJ, Summers J, Sciolla A, Gutierrez R, Ellis RJ, Abramson I, Hesselink JR, McCutchan JA, Grant I, HNRC Group. PMID: 18045694; PMCID: PMC2494949.
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    291. Selegiline transdermal system (STS) for HIV-associated cognitive impairment: open-label report of ACTG 5090. HIV Clin Trials. 2007 Nov-Dec; 8(6):437-46. Evans SR, Yeh TM, Sacktor N, Clifford DB, Simpson D, Miller EN, Ellis RJ, Valcour V, Marra CM, Millar L, Schifitto G, AIDS Clinical Trials Group and the Neurologic AIDS Research Consortium. PMID: 18042509.
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    292. Low CSF leptin levels are associated with worse learning and memory performance in HIV-infected men. J Neuroimmune Pharmacol. 2007 Dec; 2(4):352-8. Huang JS, Letendre S, Marquie-Beck J, Cherner M, McCutchan JA, Grant I, Ellis R. PMID: 18040853.
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    293. Memantine and HIV-associated cognitive impairment: a neuropsychological and proton magnetic resonance spectroscopy study. AIDS. 2007 Sep 12; 21(14):1877-86. Schifitto G, Navia BA, Yiannoutsos CT, Marra CM, Chang L, Ernst T, Jarvik JG, Miller EN, Singer EJ, Ellis RJ, Kolson DL, Simpson D, Nath A, Berger J, Shriver SL, Millar LL, Colquhoun D, Lenkinski R, Gonzalez RG, Lipton SA, Adult AIDS Clinical Trial Group (ACTG) 301, 700 Teams, HIV MRS Consortium. PMID: 17721095.
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    294. Pathogenesis of hepatitis C virus coinfection in the brains of patients infected with HIV. J Infect Dis. 2007 Aug 01; 196(3):361-70. Letendre S, Paulino AD, Rockenstein E, Adame A, Crews L, Cherner M, Heaton R, Ellis R, Everall IP, Grant I, Masliah E, HIV Neurobehavioral Research Center Group. PMID: 17597450.
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    295. Neuropsychological deficits in human immunodeficiency virus type 1 clade C-seropositive adults from South India. J Neurovirol. 2007 Jun; 13(3):195-202. Gupta JD, Satishchandra P, Gopukumar K, Wilkie F, Waldrop-Valverde D, Ellis R, Ownby R, Subbakrishna DK, Desai A, Kamat A, Ravi V, Rao BS, Satish KS, Kumar M. PMID: 17613709.
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    296. HIV suppression by HAART preserves cognitive function in advanced, immune-reconstituted AIDS patients. AIDS. 2007 May 31; 21(9):1109-17. McCutchan JA, Wu JW, Robertson K, Koletar SL, Ellis RJ, Cohn S, Taylor M, Woods S, Heaton R, Currier J, Williams PL. PMID: 17502721.
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    297. Predictive validity of demographically adjusted normative standards for the HIV Dementia Scale. J Clin Exp Neuropsychol. 2008 Jan; 30(1):83-90. Morgan EE, Woods SP, Scott JC, Childers M, Beck JM, Ellis RJ, Grant I, Heaton RK, HIV Neurobehavioral Research Center (HNRC) Group. PMID: 17852582; PMCID: PMC3659773.
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    298. NeuroAIDS in Brazil. J Neurovirol. 2007 Apr; 13(2):89-96. Ellis RJ, Joseph J, de Almeida SM. PMID: 17505977.
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    299. Neurologic complications of HIV disease and their treatment. Top HIV Med. 2007 Apr-May; 15(2):32-9. Letendre S, Ances B, Gibson S, Ellis RJ. PMID: 17485785.
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    300. Evidence-based treatment for HIV-associated dementia and cognitive impairment: why so little? PLoS Clin Trials. 2007 Mar 30; 2(3):e15. Ellis RJ. PMID: 17401455; PMCID: PMC1845157.
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    302. Meeting practical challenges of a trial involving a multitude of treatment regimens: an example of a multi-center randomized controlled clinical trial in neuroAIDS. J Neuroimmune Pharmacol. 2007 Mar; 2(1):97-104. May S, Letendre S, Haubrich R, McCutchan JA, Heaton R, Capparelli E, Ellis R. PMID: 18040832.
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    303. Clinical trials in HIV CNS disease and treatment management. J Neuroimmune Pharmacol. 2007 Mar; 2(1):20-5. Ellis RJ. PMID: 18040822.
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    304. The role of cohort studies in drug development: clinical evidence of antiviral activity of serotonin reuptake inhibitors and HMG-CoA reductase inhibitors in the central nervous system. J Neuroimmune Pharmacol. 2007 Mar; 2(1):120-7. Letendre SL, Marquie-Beck J, Ellis RJ, Woods SP, Best B, Clifford DB, Collier AC, Gelman BB, Marra C, McArthur JC, McCutchan JA, Morgello S, Simpson D, Alexander TJ, Durelle J, Heaton R, Grant I, CHARTER Group. PMID: 18040835.
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    305. Neuropathologic confirmation of definitional criteria for human immunodeficiency virus-associated neurocognitive disorders. J Neurovirol. 2007; 13(1):23-8. Cherner M, Cysique L, Heaton RK, Marcotte TD, Ellis RJ, Masliah E, Grant I, HNRC Group. PMID: 17454445.
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    306. HIV and antiretroviral therapy in the brain: neuronal injury and repair. Nat Rev Neurosci. 2007 Jan; 8(1):33-44. Ellis R, Langford D, Masliah E. PMID: 17180161.
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    307. Proton MRS and neuropsychological correlates in AIDS dementia complex: evidence of subcortical specificity. J Neuropsychiatry Clin Neurosci. 2007; 19(3):283-92. Paul RH, Yiannoutsos CT, Miller EN, Chang L, Marra CM, Schifitto G, Ernst T, Singer E, Richards T, Jarvik GJ, Price R, Meyerhoff DJ, Kolson D, Ellis RJ, Gonzalez G, Lenkinski RE, Cohen RA, Navia BA. PMID: 17827413.
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    308. Cognitive deficits and degeneration of interneurons in HIV+ methamphetamine users. Neurology. 2006 Oct 24; 67(8):1486-9. Chana G, Everall IP, Crews L, Langford D, Adame A, Grant I, Cherner M, Lazzaretto D, Heaton R, Ellis R, Masliah E, HNRC Group. PMID: 17060582.
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    309. Valproic acid does not affect markers of human immunodeficiency virus disease progression. J Neurovirol. 2006 Oct; 12(5):403-6. Ances BM, Letendre S, Buzzell M, Marquie-Beck J, Lazaretto D, Marcotte TD, Grant I, Ellis RJ, HNRC Group. PMID: 17065134.
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    310. Lithium improves HIV-associated neurocognitive impairment. AIDS. 2006 Sep 11; 20(14):1885-8. Letendre SL, Woods SP, Ellis RJ, Atkinson JH, Masliah E, van den Brande G, Durelle J, Grant I, Everall I, HNRC Group. PMID: 16954730.
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    311. Relationship of CSF leukocytosis to compartmentalized changes in MCP-1/CCL2 in the CSF of HIV-infected patients undergoing interruption of antiretroviral therapy. J Neuroimmunol. 2006 Oct; 179(1-2):180-5. Monteiro de Almeida S, Letendre S, Zimmerman J, Kolakowski S, Lazzaretto D, McCutchan JA, Ellis R. PMID: 16901548.
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    312. Human immunodeficiency virus and the central nervous system. Braz J Infect Dis. 2006 Feb; 10(1):41-50. de Almeida SM, Letendre S, Ellis R. PMID: 16767315.
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    313. Genetic attributes of cerebrospinal fluid-derived HIV-1 env. Brain. 2006 Jul; 129(Pt 7):1872-83. Pillai SK, Pond SL, Liu Y, Good BM, Strain MC, Ellis RJ, Letendre S, Smith DM, Günthard HF, Grant I, Marcotte TD, McCutchan JA, Richman DD, Wong JK. PMID: 16735456.
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    314. Characterization of interference with 6 commercial delta9-tetrahydrocannabinol immunoassays by efavirenz (glucuronide) in urine. Clin Chem. 2006 May; 52(5):896-7. Rossi S, Yaksh T, Bentley H, van den Brande G, Grant I, Ellis R. PMID: 16638958.
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    315. Cortical and subcortical neurodegeneration is associated with HIV neurocognitive impairment. AIDS. 2006 Apr 04; 20(6):879-87. Moore DJ, Masliah E, Rippeth JD, Gonzalez R, Carey CL, Cherner M, Ellis RJ, Achim CL, Marcotte TD, Heaton RK, Grant I, HNRC Group. PMID: 16549972.
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    316. Relationship of antiretroviral treatment to postmortem brain tissue viral load in human immunodeficiency virus-infected patients. J Neurovirol. 2006 Apr; 12(2):100-7. Langford D, Marquie-Beck J, de Almeida S, Lazzaretto D, Letendre S, Grant I, McCutchan JA, Masliah E, Ellis RJ. PMID: 16798671.
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    317. Neurologic complications of HIV disease and their treatments. Top HIV Med. 2006 Mar-Apr; 14(1):21-6. Letendre S, Ellis RJ. PMID: 16641524.
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    318. Clinical validation of the NeuroScreen. J Neurovirol. 2005 Dec; 11(6):503-11. Ellis RJ, Evans SR, Clifford DB, Moo LR, McArthur JC, Collier AC, Benson C, Bosch R, Simpson D, Yiannoutsos CT, Yang Y, Robertson K, Neurological AIDS Research Consortium, AIDS Clinical Trials Group Study Teams A5001 and A362. PMID: 16338744.
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    319. The effects of hepatitis C, HIV, and methamphetamine dependence on neuropsychological performance: biological correlates of disease. AIDS. 2005 Oct; 19 Suppl 3:S72-8. Letendre SL, Cherner M, Ellis RJ, Marquie-Beck J, Gragg B, Marcotte T, Heaton RK, McCutchan JA, Grant I, HNRC Group. PMID: 16251831.
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    320. Dynamics of monocyte chemoattractant protein type one (MCP-1) and HIV viral load in human cerebrospinal fluid and plasma. J Neuroimmunol. 2005 Dec; 169(1-2):144-52. Monteiro de Almeida S, Letendre S, Zimmerman J, Lazzaretto D, McCutchan A, Ellis R. PMID: 16182380.
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    321. A battery approach for measuring neuropsychological change. Arch Clin Neuropsychol. 2006 Jan; 21(1):83-9. Woods SP, Childers M, Ellis RJ, Guaman S, Grant I, Heaton RK, HIV Neurobehavioral Research Center (HNRC) Group. PMID: 16169705.
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    322. Brain mitochondrial injury in human immunodeficiency virus-seropositive (HIV+) individuals taking nucleoside reverse transcriptase inhibitors. J Neurovirol. 2005 Aug; 11(4):356-64. Schweinsburg BC, Taylor MJ, Alhassoon OM, Gonzalez R, Brown GG, Ellis RJ, Letendre S, Videen JS, McCutchan JA, Patterson TL, Grant I, HNRC Group. PMID: 16206458.
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    325. Population pharmacokinetics of abacavir in plasma and cerebrospinal fluid. Antimicrob Agents Chemother. 2005 Jun; 49(6):2504-6. Capparelli EV, Letendre SL, Ellis RJ, Patel P, Holland D, McCutchan JA. PMID: 15917556; PMCID: PMC1140502.
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    326. Genetic composition of human immunodeficiency virus type 1 in cerebrospinal fluid and blood without treatment and during failing antiretroviral therapy. J Virol. 2005 Feb; 79(3):1772-88. Strain MC, Letendre S, Pillai SK, Russell T, Ignacio CC, Günthard HF, Good B, Smith DM, Wolinsky SM, Furtado M, Marquie-Beck J, Durelle J, Grant I, Richman DD, Marcotte T, McCutchan JA, Ellis RJ, Wong JK. PMID: 15650202; PMCID: PMC544082.
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    327. The monocyte chemotactic protein-1 -2578G allele is associated with elevated MCP-1 concentrations in cerebrospinal fluid. J Neuroimmunol. 2004 Dec; 157(1-2):193-6. Letendre S, Marquie-Beck J, Singh KK, de Almeida S, Zimmerman J, Spector SA, Grant I, Ellis R, HNRC Group. PMID: 15579297.
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    328. CCR2 polymorphisms affect neuropsychological impairment in HIV-1-infected adults. J Neuroimmunol. 2004 Dec; 157(1-2):185-92. Singh KK, Ellis RJ, Marquie-Beck J, Letendre S, Heaton RK, Grant I, Spector SA. PMID: 15579296.
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    331. Altered P-glycoprotein expression in AIDS patients with HIV encephalitis. J Neuropathol Exp Neurol. 2004 Oct; 63(10):1038-47. Langford D, Grigorian A, Hurford R, Adame A, Ellis RJ, Hansen L, Masliah E. PMID: 15535131.
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    339. Molecular chaperones: Plugging the transport gap. Nature. 2003 Feb 20; 421(6925):801-2. Ellis RJ. PMID: 12594497.
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    341. Neurocognitive dysfunction predicts postmortem findings of HIV encephalitis. Neurology. 2002 Nov 26; 59(10):1563-7. Cherner M, Masliah E, Ellis RJ, Marcotte TD, Moore DJ, Grant I, Heaton RK. PMID: 12451198.
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