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Jared Young

Title(s)Professor , Psychiatry
SchoolHealth Sciences
Address9500 Gilman Drive #0804
La Jolla CA 92093
Phone619-471-0497
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    Biography

    Dr. Young received his BSc. (Hons) in Psychology with Biology and his Ph.D. in Psychopharmacology in the Department of Neuroscience, at the University of Edinburgh, sponsored by the Fujisawa Institute for Neuroscience in Edinburgh. He worked for a year at Organon Laboratories in Scotland prior to his arrival at UCSD to conduct his Post-Doctoral training in 2006. This training was primarily with Profs. Mark Geyer and Dilip Jeste at the Consortium for Translational Research in Neuropsychopharmacology (www.ctrin.org), MIRECC San Diego VA (http://www.mirecc.va.gov/visn22), and the Stein Institute for Research on Aging (www.sira.ucsd.edu) respectively. Dr. Young became a Faculty member in 2009.

    Research Interests

    Dr. Young investigates the molecular biology and neural circuitry underlying behavioral abnormalities occurring in major neuropsychiatric disorders. Debilitating forms of mental illness are prevalent but treatment options for these disorders remain limited. For example, despite the fact that cognitive deficits are a major determinant of impaired function in these patients, there are no approved treatments. Despite molecular and genetic advances, treatment development has not kept pace. One major roadblock for treatment development has been the scarcity of effective cross-species models. Dr. Young uses cutting-edge neuroscience to develop novel and sophisticated cross-species models to identify targetable mechanisms to treat mental illnesses.

    Clinical Focus

    In order to examine the molecular biology and neural circuitry underlying behavioral abnormalities occurring in major neuropsychiatric disorders, we characterize such abnormalities using reverse-translated paradigms. For example, using the human 5-choice continuous performance task (originally developed for mice), we have characterized EEG and fMRI abnormalities that occur in patients with bipolar disorder and schizophrenia, the impact smoking, and smoking cessation, has on attentive properties. By identifying neural mechanisms in patients and healthy subjects, these mechanisms can then be investigated in greater depth using the corresponding animal models.

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    Collapse Research Activities and Funding
    Cannabis use and the endocannabinoid system in bipolar disorder
    NIH/NIDA R01DA043535May 1, 2018 - Feb 28, 2023
    Role: Co-Principal Investigator
    Cross-species studies of smoking effects on cognition and neuroinflammation in HIV
    NIH/NIDA R01DA044909Aug 1, 2017 - Jul 31, 2022
    Role: Principal Investigator
    Neurophysiological biomarkers of behavioral dimensions from cross-species paradigms
    NIH/NIMH UH3MH109168Apr 1, 2016 - Jun 30, 2020
    Role: Principal Investigator
    Neurophysiological biomarkers of behavioral dimensions from cross-species paradigms
    NIH/NIMH UH2MH109168Apr 1, 2016 - Mar 31, 2018
    Role: Principal Investigator
    Oxytocin as a therapeutic target for Schizophrenia
    NIH/NIMH R01MH103421Apr 1, 2015 - Mar 31, 2020
    Role: Principal Investigator
    A model organism of brain circuitry and behavioral switching for bipolar disorder
    NIH/NIMH R01MH104344Jul 1, 2014 - May 31, 2018
    Role: Principal Investigator
    Alpha 7 nicotinic receptor-mediated enhancement of reinforcement learning
    NIH/NIMH R21MH101579Apr 1, 2014 - Mar 31, 2016
    Role: Principal Investigator
    Visuospatial priming in rats: A novel animal model for Tourette Syndrome
    NIH/NIMH R21MH091571Jul 21, 2010 - Apr 30, 2013
    Role: Principal Investigator
    The rodent continuous performance task: Filling the vigilance translational gap
    NIH/NIMH R21MH085221Jul 7, 2009 - Jun 30, 2012
    Role: Principal Investigator

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    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Sustained attention and vigilance deficits associated with HIV and a history of methamphetamine dependence. Drug Alcohol Depend. 2020 Aug 22; 215:108245. Pocuca N, Young JW, MacQueen DA, Letendre S, Heaton RK, Geyer MA, Perry W, Grant I, Minassian A. PMID: 32871507.
      View in: PubMed   Mentions:    Fields:    
    2. Converging evidence that short-active photoperiod increases acetylcholine signaling in the hippocampus. Cogn Affect Behav Neurosci. 2020 Aug 13. Cope ZA, Lavadia ML, Joosen AJM, van de Cappelle CJA, Lara JC, Huval A, Kwiatkowski MK, Picciotto MR, Mineur YS, Dulcis D, Young JW. PMID: 32794101.
      View in: PubMed   Mentions:    Fields:    
    3. Short-active photoperiod gestation induces psychiatry-relevant behavior in healthy mice but a resiliency to such effects are seen in mice with reduced dopamine transporter expression. Sci Rep. 2020 Jun 23; 10(1):10217. Kwiatkowski MA, Cope ZA, Lavadia ML, van de Cappelle CJA, Dulcis D, Young JW. PMID: 32576854.
      View in: PubMed   Mentions:    Fields:    
    4. Amphetamine improves rat 5-choice continuous performance test (5C-CPT) irrespective of concurrent low-dose haloperidol treatment. Psychopharmacology (Berl). 2020 Jul; 237(7):1959-1972. Young JW, Roberts BZ, Breier M, Swerdlow NR. PMID: 32318751.
      View in: PubMed   Mentions:    Fields:    
    5. Moderate prenatal alcohol exposure impairs cognitive control, but not attention, on a rodent touchscreen continuous performance task. Genes Brain Behav. 2020 Mar 06; e12652. Olguin SL, Thompson SM, Young JW, Brigman JL. PMID: 32144885.
      View in: PubMed   Mentions:    Fields:    
    6. The D2-family receptor agonist bromocriptine but, not nicotine, reverses NMDA receptor antagonist-induced working memory deficits in the radial arm maze in mice. Neurobiol Learn Mem. 2020 02; 168:107159. MacQueen DA, Young JW. PMID: 31911198.
      View in: PubMed   Mentions:    Fields:    
    7. Btbd3 expression regulates compulsive-like and exploratory behaviors in mice. Transl Psychiatry. 2019 09 09; 9(1):222. Thompson SL, Welch AC, Ho EV, Bessa JM, Portugal-Nunes C, Morais M, Young JW, Knowles JA, Dulawa SC. PMID: 31501410.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    8. Reconsidering the Latent Structure of Negative Symptoms in Schizophrenia: A Review of Evidence Supporting the 5 Consensus Domains. Schizophr Bull. 2019 06 18; 45(4):725-729. Strauss GP, Ahmed AO, Young JW, Kirkpatrick B. PMID: 30541136.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    9. Current status of the neurobiology of aggression and impulsivity. Neuropharmacology. 2019 09 15; 156:107665. Slattery DA, Young JW. PMID: 31176758.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    10. Convergent neural substrates of inattention in bipolar disorder patients and dopamine transporter-deficient mice using the 5-choice CPT. Bipolar Disord. 2020 02; 22(1):46-58. Young JW, Geyer MA, Halberstadt AL, van Enkhuizen J, Minassian A, Khan A, Perry W, Eyler LT. PMID: 31025493.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    11. Oxytocin improves probabilistic reversal learning but not effortful motivation in Brown Norway rats. Neuropharmacology. 2019 05 15; 150:15-26. Roberts BZ, Young JW, He YV, Cope ZA, Shilling PD, Feifel D. PMID: 30844406.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    12. The importance and depth of reproducibility in rodent models of psychiatric diseases. Pharmacol Biochem Behav. 2019 03; 178:1-2. Young JW, Einat H. PMID: 30777154.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    13. Evidence for light-entrainment-induced switching between depression- & mania-relevant behaviors in mice. Neuropsychopharmacology. 2019 09; 44(10):1679-1680. Young JW, Cope ZA, Romoli B, Schrurs E, Joosen A, van Enkhuizen J, Sharp RF, Dulcis D. PMID: 30787425.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    14. Nicotine improves probabilistic reward learning in wildtype but not alpha7 nAChR null mutants, yet alpha7 nAChR agonists do not improve probabilistic learning. Eur Neuropsychopharmacol. 2018 11; 28(11):1217-1231. Milienne-Petiot M, Higa KK, Grim A, Deben D, Groenink L, Twamley EW, Geyer MA, Young JW. PMID: 30213668.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    15. Amphetamine improves mouse and human attention in the 5-choice continuous performance test. Neuropharmacology. 2018 08; 138:87-96. MacQueen DA, Minassian A, Kenton JA, Geyer MA, Perry W, Brigman JL, Young JW. PMID: 29859849.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    16. Correction to: The Effects of Cariprazine and Aripiprazole on PCP-Induced Deficits on Attention Assessed in the 5-Choice Serial Reaction Time Task. Psychopharmacology (Berl). 2018 05; 235(5):1621. Barnes SA, Young JW, Markou A, Adham N, Gyertyán I, Kiss B. PMID: 29564481.
      View in: PubMed   Mentions:    Fields:    
    17. Reverse translated and gold standard continuous performance tests predict global cognitive performance in schizophrenia. Transl Psychiatry. 2018 04 12; 8(1):80. Bismark AW, Thomas ML, Tarasenko M, Shiluk AL, Rackelmann SY, Young JW, Light GA. PMID: 29643355.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    18. Mice with reduced DAT levels recreate seasonal-induced switching between states in bipolar disorder. Neuropsychopharmacology. 2018 07; 43(8):1721-1731. Young JW, Cope ZA, Romoli B, Schrurs E, van Enkhuizen J, Sharp RF, Dulcis D. PMID: 29520059.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    19. The Effects of Cariprazine and Aripiprazole on PCP-Induced Deficits on Attention Assessed in the 5-Choice Serial Reaction Time Task. Psychopharmacology (Berl). 2018 05; 235(5):1403-1414. Barnes SA, Young JW, Markou A, Adham N, Gyertyán I, Kiss B. PMID: 29473089.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    20. Cross-Species Neurophysiological Biomarkers of Attentional Dysfunction in Schizophrenia: Bridging the Translational Gap. Neuropsychopharmacology. 2018 01; 43(1):230-231. Young JW, Light GA. PMID: 29192660.
      View in: PubMed   Mentions:    Fields:    
    21. Cognitive Phenotypes for Biomarker Identification in Mental Illness: Forward and Reverse Translation. Curr Top Behav Neurosci. 2018; 40:111-166. MacQueen DA, Young JW, Cope ZA. PMID: 29858983.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    22. Dopamine transporter knockdown mice in the behavioral pattern monitor: A robust, reproducible model for mania-relevant behaviors. Pharmacol Biochem Behav. 2019 03; 178:42-50. Kwiatkowski MA, Hellemann G, Sugar CA, Cope ZA, Minassian A, Perry W, Geyer MA, Young JW. PMID: 29289701.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    23. Tolcapone-Enhanced Neurocognition in Healthy Adults: Neural Basis and Predictors. Int J Neuropsychopharmacol. 2017 12 01; 20(12):979-987. Bhakta SG, Light GA, Talledo JA, Balvaneda B, Hughes E, Alvarez A, Rana BK, Young JW, Swerdlow NR. PMID: 29020372.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    24. Phencyclidine increased while isolation rearing did not affect progressive ratio responding in rats: Investigating potential models of amotivation in schizophrenia. Behav Brain Res. 2019 05 17; 364:413-422. Amitai N, Powell SB, Young JW. PMID: 29175446.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    25. The COMT Val158Met Polymorphism and Exploratory Behavior in Bipolar Mania. Mol Neuropsychiatry. 2018 Feb; 3(3):151-156. Minassian A, Young JW, Geyer MA, Kelsoe JR, Perry W. PMID: 29594134.
      View in: PubMed   Mentions:
    26. Transgenic mice expressing HIV-1 envelope protein gp120 in the brain as an animal model in neuroAIDS research. J Neurovirol. 2018 04; 24(2):156-167. Thaney VE, Sanchez AB, Fields JA, Minassian A, Young JW, Maung R, Kaul M. PMID: 29075998.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    27. Amphetamine Modestly Improves Conners' Continuous Performance Test Performance in Healthy Adults. J Int Neuropsychol Soc. 2018 03; 24(3):283-293. MacQueen DA, Minassian A, Henry BL, Geyer MA, Young JW, Perry W. PMID: 29032769.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    28. Blockade of dopamine D1-family receptors attenuates the mania-like hyperactive, risk-preferring, and high motivation behavioral profile of mice with low dopamine transporter levels. J Psychopharmacol. 2017 10; 31(10):1334-1346. Milienne-Petiot M, Groenink L, Minassian A, Young JW. PMID: 28950781.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    29. Modafinil improves attentional performance in healthy, non-sleep deprived humans at doses not inducing hyperarousal across species. Neuropharmacology. 2017 Oct; 125:254-262. Cope ZA, Minassian A, Kreitner D, MacQueen DA, Milienne-Petiot M, Geyer MA, Perry W, Young JW. PMID: 28774856.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    30. The 5 choice continuous performance test (5C-CPT): A novel tool to assess cognitive control across species. J Neurosci Methods. 2017 Dec 01; 292:53-60. Bhakta SG, Young JW. PMID: 28754432.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    31. Preclinical Models to Investigate Mechanisms of Negative Symptoms in Schizophrenia. Schizophr Bull. 2017 07 01; 43(4):706-711. Barnes SA, Der-Avakian A, Young JW. PMID: 28586462.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    32. Relationship between effortful motivation and neurocognition in schizophrenia. Schizophr Res. 2018 03; 193:69-76. Bismark AW, Thomas ML, Tarasenko M, Shiluk AL, Rackelmann SY, Young JW, Light GA. PMID: 28673753.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    33. Introduction to the special issue from the 2015 meeting of the International Behavioral Neuroscience Society. Neurosci Biobehav Rev. 2017 05; 76(Pt B):185-186. Pletnikov M, Young JW, Hall FS, Kent S. PMID: 28300550.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    34. Brexpiprazole reduces hyperactivity, impulsivity, and risk-preference behavior in mice with dopamine transporter knockdown-a model of mania. Psychopharmacology (Berl). 2017 Mar; 234(6):1017-1028. Milienne-Petiot M, Geyer MA, Arnt J, Young JW. PMID: 28160035.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    35. Striatal dopamine D1 receptor suppression impairs reward-associative learning. Behav Brain Res. 2017 04 14; 323:100-110. Higa KK, Young JW, Ji B, Nichols DE, Geyer MA, Zhou X. PMID: 28143767.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    36. The Five-Choice Continuous Performance Task (5C-CPT): A Cross-Species Relevant Paradigm for Assessment of Vigilance and Response Inhibition in Rodents. Curr Protoc Neurosci. 2017 01 03; 78:9.56.1-9.56.18. Cope ZA, Young JW. PMID: 28046200.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    37. Neurophysiological Characterization of Attentional Performance Dysfunction in Schizophrenia Patients in a Reverse-Translated Task. Neuropsychopharmacology. 2017 May; 42(6):1338-1348. Young JW, Bismark AW, Sun Y, Zhang W, McIlwain M, Grootendorst I, Light GA. PMID: 27917869.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    38. Adolescent GBR12909 exposure induces oxidative stress, disrupts parvalbumin-positive interneurons, and leads to hyperactivity and impulsivity in adult mice. Neuroscience. 2017 03 14; 345:166-175. Khan A, de Jong LA, Kamenski ME, Higa KK, Lucero JD, Young JW, Behrens MM, Powell SB. PMID: 27890827.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    39. Research Domain Criteria versus DSM V: How does this debate affect attempts to model corticostriatal dysfunction in animals? Neurosci Biobehav Rev. 2017 05; 76(Pt B):301-316. Young JW, Winstanley CA, Brady AM, Hall FS. PMID: 27826070.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    40. The effects of reduced dopamine transporter function and chronic lithium on motivation, probabilistic learning, and neurochemistry in mice: Modeling bipolar mania. Neuropharmacology. 2017 02; 113(Pt A):260-270. Milienne-Petiot M, Kesby JP, Graves M, van Enkhuizen J, Semenova S, Minassian A, Markou A, Geyer MA, Young JW. PMID: 27732870.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    41. Premature responses in the five-choice serial reaction time task reflect rodents' temporal strategies: evidence from no-light and pharmacological challenges. Psychopharmacology (Berl). 2016 Oct; 233(19-20):3513-25. Cope ZA, Halberstadt AL, van Enkhuizen J, Flynn AD, Breier M, Swerdlow NR, Geyer MA, Young JW. PMID: 27534540.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    42. Perseveration by NK1R-/- ('knockout') mice is blunted by doses of methylphenidate that affect neither other aspects of their cognitive performance nor the behaviour of wild-type mice in the 5-Choice Continuous Performance Test. J Psychopharmacol. 2016 09; 30(9):837-47. Pillidge K, Porter AJ, Young JW, Stanford SC. PMID: 27097734.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    43. The mood stabilizer valproic acid opposes the effects of dopamine on circadian rhythms. Neuropharmacology. 2016 08; 107:262-270. Landgraf D, Joiner WJ, McCarthy MJ, Kiessling S, Barandas R, Young JW, Cermakian N, Welsh DK. PMID: 27033596.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    44. Effect of 5-HT2A and 5-HT2C receptors on temporal discrimination by mice. Neuropharmacology. 2016 08; 107:364-375. Halberstadt AL, Sindhunata IS, Scheffers K, Flynn AD, Sharp RF, Geyer MA, Young JW. PMID: 27020041.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    45. Wet or dry: translatable "water mazes" for mice and humans. J Clin Invest. 2016 Feb; 126(2):477-9. Higa KK, Young JW, Geyer MA. PMID: 26784538.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    46. Locomotor Profiling from Rodents to the Clinic and Back Again. Curr Top Behav Neurosci. 2016; 28:287-303. Young JW, Minassian A, Geyer MA. PMID: 27418071.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    47. Dispatches from the International Behavioral Neuroscience Society meeting 2014. Introduction. Behav Brain Res. 2015 Dec 15; 295:1-2. Brigman JL, Young JW, Pletnikov M, Kent S. PMID: 26549148.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    48. Negative visuospatial priming in isolation-reared rats: Evidence of resistance to the disruptive effects of amphetamine. Cogn Affect Behav Neurosci. 2015 Dec; 15(4):901-14. Amitai N, Powell S, Weber M, Swerdlow NR, Young JW. PMID: 26220402.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    49. Differences in the performance of NK1R-/- ('knockout') and wildtype mice in the 5-Choice Continuous Performance Test. Behav Brain Res. 2016 Feb 01; 298(Pt B):268-77. Porter AJ, Pillidge K, Stanford SC, Young JW. PMID: 26522842.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    50. Introduction to the special issue from the 2014 meeting of the International Behavioral Neuroscience Society. Neurosci Biobehav Rev. 2015 Nov; 58:1-3. Young JW, Hall FS, Pletnikov M, Kent S. PMID: 26672720.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    51. Amphetamine increases activity but not exploration in humans and mice. Psychopharmacology (Berl). 2016 Jan; 233(2):225-33. Minassian A, Young JW, Cope ZA, Henry BL, Geyer MA, Perry W. PMID: 26449721.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    52. Investigating the underlying mechanisms of aberrant behaviors in bipolar disorder from patients to models: Rodent and human studies. Neurosci Biobehav Rev. 2015 Nov; 58:4-18. van Enkhuizen J, Geyer MA, Minassian A, Perry W, Henry BL, Young JW. PMID: 26297513.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    53. Effort-Based Decision-Making Paradigms for Clinical Trials in Schizophrenia: Part 2—External Validity and Correlates. Schizophr Bull. 2015 Sep; 41(5):1055-65. Horan WP, Reddy LF, Barch DM, Buchanan RW, Dunayevich E, Gold JM, Marder SR, Wynn JK, Young JW, Green MF. PMID: 26209546.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    54. Translational Rodent Paradigms to Investigate Neuromechanisms Underlying Behaviors Relevant to Amotivation and Altered Reward Processing in Schizophrenia. Schizophr Bull. 2015 Sep; 41(5):1024-34. Young JW, Markou A. PMID: 26194891.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimals
    55. Modeling bipolar disorder in mice by increasing acetylcholine or dopamine: chronic lithium treats most, but not all features. Psychopharmacology (Berl). 2015 Sep; 232(18):3455-67. van Enkhuizen J, Milienne-Petiot M, Geyer MA, Young JW. PMID: 26141192.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    56. Effort-Based Decision-Making Paradigms for Clinical Trials in Schizophrenia: Part 1—Psychometric Characteristics of 5 Paradigms. Schizophr Bull. 2015 Sep; 41(5):1045-54. Reddy LF, Horan WP, Barch DM, Buchanan RW, Dunayevich E, Gold JM, Lyons N, Marder SR, Treadway MT, Wynn JK, Young JW, Green MF. PMID: 26142081.
      View in: PubMed   Mentions: 29     Fields:    Translation:Humans
    57. Neural mechanisms regulating different forms of risk-related decision-making: Insights from animal models. Neurosci Biobehav Rev. 2015 Nov; 58:147-67. Orsini CA, Moorman DE, Young JW, Setlow B, Floresco SB. PMID: 26072028.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansAnimals
    58. Negative affective states and cognitive impairments in nicotine dependence. Neurosci Biobehav Rev. 2015 Nov; 58:168-85. Hall FS, Der-Avakian A, Gould TJ, Markou A, Shoaib M, Young JW. PMID: 26054790.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    59. Restoration of Sp4 in Forebrain GABAergic Neurons Rescues Hypersensitivity to Ketamine in Sp4 Hypomorphic Mice. Int J Neuropsychopharmacol. 2015 Jun 02; 18(11):pyv063. Higa KK, Ji B, Buell MR, Risbrough VB, Powell SB, Young JW, Geyer MA, Zhou X. PMID: 26037489.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    60. Early Adolescent Emergence of Reversal Learning Impairments in Isolation-Reared Rats. Dev Neurosci. 2015; 37(3):253-62. Powell SB, Khan A, Young JW, Scott CN, Buell MR, Caldwell S, Tsan E, de Jong LA, Acheson DT, Lucero J, Geyer MA, Behrens MM. PMID: 26022788.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    61. GlyT-1 Inhibition Attenuates Attentional But Not Learning or Motivational Deficits of the Sp4 Hypomorphic Mouse Model Relevant to Psychiatric Disorders. Neuropsychopharmacology. 2015 Nov; 40(12):2715-26. Young JW, Kamenski ME, Higa KK, Light GA, Geyer MA, Zhou X. PMID: 25907107.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    62. Investigating the mechanism(s) underlying switching between states in bipolar disorder. Eur J Pharmacol. 2015 Jul 15; 759:151-62. Young JW, Dulcis D. PMID: 25814263.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimals
    63. Translational and Early Phase Strategies for Treatment Development: Report of ISCTM Autumn 2013 Symposium. Innov Clin Neurosci. 2015 Mar-Apr; 12(3-4):5S-10S. Young JW, Potter WZ, Riley S, Groeneveld GJ, Kinon BJ, Egan MF, Feltner DE. PMID: 25977839.
      View in: PubMed   Mentions:
    64. Methamphetamine Exposure Combined with HIV-1 Disease or gp120 Expression: Comparison of Learning and Executive Functions in Humans and Mice. Neuropsychopharmacology. 2015 Jul; 40(8):1899-909. Kesby JP, Heaton RK, Young JW, Umlauf A, Woods SP, Letendre SL, Markou A, Grant I, Semenova S. PMID: 25652249.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimals
    65. Developing treatments for cognitive deficits in schizophrenia: the challenge of translation. J Psychopharmacol. 2015 Feb; 29(2):178-96. Young JW, Geyer MA. PMID: 25516372.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimals
    66. The catecholaminergic-cholinergic balance hypothesis of bipolar disorder revisited. Eur J Pharmacol. 2015 Apr 15; 753:114-26. van Enkhuizen J, Janowsky DS, Olivier B, Minassian A, Perry W, Young JW, Geyer MA. PMID: 25107282.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimals
    67. Reduced dopamine transporter functioning induces high-reward risk-preference consistent with bipolar disorder. Neuropsychopharmacology. 2014 Dec; 39(13):3112-22. van Enkhuizen J, Henry BL, Minassian A, Perry W, Milienne-Petiot M, Higa KK, Geyer MA, Young JW. PMID: 25005251.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimals
    68. Inhibition of protein translation by the DISC1-Boymaw fusion gene from a Scottish family with major psychiatric disorders. Hum Mol Genet. 2014 Nov 01; 23(21):5683-705. Ji B, Higa KK, Kim M, Zhou L, Young JW, Geyer MA, Zhou X. PMID: 24908665.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    69. Altered exploration and sensorimotor gating of the chakragati mouse model of schizophrenia. Behav Neurosci. 2014 Aug; 128(4):460-7. Young JW, Ratty A, Dawe GS, Geyer MA. PMID: 24708299.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    70. Isolation rearing effects on probabilistic learning and cognitive flexibility in rats. Cogn Affect Behav Neurosci. 2014 Mar; 14(1):388-406. Amitai N, Young JW, Higa K, Sharp RF, Geyer MA, Powell SB. PMID: 23943516.
      View in: PubMed   Mentions: 14     Fields:    Translation:Animals
    71. Prepulse inhibition in HIV-1 gp120 transgenic mice after withdrawal from chronic methamphetamine. Behav Pharmacol. 2014 Feb; 25(1):12-22. Henry BL, Geyer MA, Buell MR, Perry W, Young JW, Minassian A. PMID: 24281153.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimals
    72. Sleep deprivation impairs performance in the 5-choice continuous performance test: similarities between humans and mice. Behav Brain Res. 2014 Mar 15; 261:40-8. van Enkhuizen J, Acheson D, Risbrough V, Drummond S, Geyer MA, Young JW. PMID: 24333377.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimals
    73. Dopamine depletion attenuates some behavioral abnormalities in a hyperdopaminergic mouse model of bipolar disorder. J Affect Disord. 2014 Feb; 155:247-54. van Enkhuizen J, Geyer MA, Halberstadt AL, Zhuang X, Young JW. PMID: 24287168.
      View in: PubMed   Mentions: 17     Fields:    Translation:Animals
    74. Evaluating the role of the alpha-7 nicotinic acetylcholine receptor in the pathophysiology and treatment of schizophrenia. Biochem Pharmacol. 2013 Oct 15; 86(8):1122-32. Young JW, Geyer MA. PMID: 23856289.
      View in: PubMed   Mentions: 40     Fields:    Translation:Humans
    75. Reward learning as a potential target for pharmacological augmentation of cognitive remediation for schizophrenia: a roadmap for preclinical development. Front Neurosci. 2013; 7:103. Acheson DT, Twamley EW, Young JW. PMID: 23785309.
      View in: PubMed   Mentions:
    76. Prolonged Ketamine Effects in Sp4 Hypomorphic Mice: Mimicking Phenotypes of Schizophrenia. PLoS One. 2013; 8(6):e66327. Ji B, Wang X, Pinto-Duarte A, Kim M, Caldwell S, Young JW, Behrens MM, Sejnowski TJ, Geyer MA, Zhou X. PMID: 23823008.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    77. Inhibitory deficits in euthymic bipolar disorder patients assessed in the human behavioral pattern monitor. J Affect Disord. 2013 Sep 25; 150(3):948-54. Henry BL, Minassian A, Patt VM, Hua J, Young JW, Geyer MA, Perry W. PMID: 23759280.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    78. Further evidence for Clock?19 mice as a model for bipolar disorder mania using cross-species tests of exploration and sensorimotor gating. Behav Brain Res. 2013 Jul 15; 249:44-54. van Enkhuizen J, Minassian A, Young JW. PMID: 23623885.
      View in: PubMed   Mentions: 11     Fields:    Translation:Animals
    79. Bridging the bench to bedside gap: validation of a reverse-translated rodent continuous performance test using functional magnetic resonance imaging. Psychiatry Res. 2013 Jun 30; 212(3):183-91. McKenna BS, Young JW, Dawes SE, Asgaard GL, Eyler LT. PMID: 23570915.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    80. Demand and modality of directed attention modulate "pre-attentive" sensory processes in schizophrenia patients and nonpsychiatric controls. Schizophr Res. 2013 May; 146(1-3):326-35. Rissling AJ, Park SH, Young JW, Rissling MB, Sugar CA, Sprock J, Mathias DJ, Pela M, Sharp RF, Braff DL, Light GA. PMID: 23490760.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    81. Cognitive performance and response inhibition in developmentally vitamin D (DVD)-deficient rats. Behav Brain Res. 2013 Apr 01; 242:47-53. Turner KM, Young JW, McGrath JJ, Eyles DW, Burne TH. PMID: 23275047.
      View in: PubMed   Mentions: 17     Fields:    Translation:Animals
    82. Nicotinic agonist-induced improvement of vigilance in mice in the 5-choice continuous performance test. Behav Brain Res. 2013 Mar 01; 240:119-33. Young JW, Meves JM, Geyer MA. PMID: 23201359.
      View in: PubMed   Mentions: 33     Fields:    Translation:Animals
    83. Chronic valproate attenuates some, but not all, facets of mania-like behaviour in mice. Int J Neuropsychopharmacol. 2013 Jun; 16(5):1021-31. van Enkhuizen J, Geyer MA, Kooistra K, Young JW. PMID: 23164454.
      View in: PubMed   Mentions: 21     Fields:    Translation:Animals
    84. Consideration of species differences in developing novel molecules as cognition enhancers. Neurosci Biobehav Rev. 2013 Nov; 37(9 Pt B):2181-93. Young JW, Jentsch JD, Bussey TJ, Wallace TL, Hutcheson DM. PMID: 23064177.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimals
    85. A novel visuospatial priming task for rats with relevance to Tourette syndrome and modulation of dopamine levels. Neurosci Biobehav Rev. 2013 Jul; 37(6):1139-49. Amitai N, Weber M, Swerdlow NR, Sharp RF, Breier MR, Halberstadt AL, Young JW. PMID: 23010529.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    86. Differential effects of dopamine transporter inhibitors in the rodent Iowa gambling task: relevance to mania. Psychopharmacology (Berl). 2013 Feb; 225(3):661-74. van Enkhuizen J, Geyer MA, Young JW. PMID: 22945515.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimals
    87. Behavioral effects of chronic methamphetamine treatment in HIV-1 gp120 transgenic mice. Behav Brain Res. 2013 Jan 01; 236(1):210-220. Henry BL, Geyer MA, Buell M, Perry W, Young JW, Minassian A. PMID: 22960458.
      View in: PubMed   Mentions: 14     Fields:    Translation:Animals
    88. The 3rd Schizophrenia International Research Society Conference, 14-18 April 2012, Florence, Italy: summaries of oral sessions. Schizophr Res. 2012 Oct; 141(1):e1-e24. Abbs B, Achalia RM, Adelufosi AO, Aktener AY, Beveridge NJ, Bhakta SG, Blackman RK, Bora E, Byun MS, Cabanis M, Carrion R, Castellani CA, Chow TJ, Dmitrzak-Weglarz M, Gayer-Anderson C, Gomes FV, Haut K, Hori H, Kantrowitz JT, Kishimoto T, Lee FH, Lin A, Palaniyappan L, Quan M, Rubio MD, Ruiz de Azúa S, Sahoo S, Strauss GP, Szczepankiewicz A, Thompson AD, Trotta A, Tully LM, Uchida H, Velthorst E, Young JW, O'Shea A, Delisi LE. PMID: 22910407.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    89. Four factors underlying mouse behavior in an open field. Behav Brain Res. 2012 Jul 15; 233(1):55-61. Tanaka S, Young JW, Halberstadt AL, Masten VL, Geyer MA. PMID: 22569582.
      View in: PubMed   Mentions: 21     Fields:    Translation:Animals
    90. Attentional processing in C57BL/6J mice exposed to developmental vitamin D deficiency. PLoS One. 2012; 7(4):e35896. Harms LR, Turner KM, Eyles DW, Young JW, McGrath JJ, Burne TH. PMID: 22563415.
      View in: PubMed   Mentions: 11     Fields:    Translation:Animals
    91. Measuring the construct of executive control in schizophrenia: defining and validating translational animal paradigms for discovery research. Neurosci Biobehav Rev. 2013 Nov; 37(9 Pt B):2125-40. Gilmour G, Arguello A, Bari A, Brown VJ, Carter C, Floresco SB, Jentsch DJ, Tait DS, Young JW, Robbins TW. PMID: 22548905.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimals
    92. Hippocampal calbindin-1 immunoreactivity correlate of recognition memory performance in aged mice. Neurosci Lett. 2012 May 10; 516(1):161-5. Soontornniyomkij V, Risbrough VB, Young JW, Soontornniyomkij B, Jeste DV, Achim CL. PMID: 22503902.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    93. Examining the genetic and neural components of cognitive flexibility using mice. Physiol Behav. 2012 Dec 05; 107(5):666-9. Brigman JL, Powell EM, Mittleman G, Young JW. PMID: 22234243.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    94. Behavioral animal models to assess pro-cognitive treatments for schizophrenia. Handb Exp Pharmacol. 2012; (213):39-79. Young JW, Amitai N, Geyer MA. PMID: 23027412.
      View in: PubMed   Mentions: 11     Fields:    Translation:Animals
    95. Predictive animal models of mania: hits, misses and future directions. Br J Pharmacol. 2011 Oct; 164(4):1263-84. Young JW, Henry BL, Geyer MA. PMID: 21410454.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansAnimals
    96. D1 receptor activation improves vigilance in rats as measured by the 5-choice continuous performance test. Psychopharmacology (Berl). 2012 Mar; 220(1):129-41. Barnes SA, Young JW, Neill JC. PMID: 21901319.
      View in: PubMed   Mentions: 19     Fields:    Translation:Animals
    97. Repeated assessment of exploration and novelty seeking in the human behavioral pattern monitor in bipolar disorder patients and healthy individuals. PLoS One. 2011; 6(8):e24185. Minassian A, Henry BL, Young JW, Masten V, Geyer MA, Perry W. PMID: 21912623.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    98. Factor analysis of attentional set-shifting performance in young and aged mice. Behav Brain Funct. 2011 Aug 12; 7:33. Tanaka S, Young JW, Gresack JE, Geyer MA, Risbrough VB. PMID: 21838910.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    99. Delayed procedural learning in a7-nicotinic acetylcholine receptor knockout mice. Genes Brain Behav. 2011 Oct; 10(7):720-33. Young JW, Meves JM, Tarantino IS, Caldwell S, Geyer MA. PMID: 21679297.
      View in: PubMed   Mentions: 34     Fields:    Translation:Animals
    100. Mouse pharmacological models of cognitive disruption relevant to schizophrenia. Neuropharmacology. 2012 Mar; 62(3):1381-90. Young JW, Powell SB, Geyer MA. PMID: 21726569.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimals
    101. Rats tested after a washout period from sub-chronic PCP administration exhibited impaired performance in the 5-Choice Continuous Performance Test (5C-CPT) when the attentional load was increased. Neuropharmacology. 2012 Mar; 62(3):1432-41. Barnes SA, Young JW, Neill JC. PMID: 21569782.
      View in: PubMed   Mentions: 26     Fields:    Translation:Animals
    102. The effect of reduced dopamine D4 receptor expression in the 5-choice continuous performance task: Separating response inhibition from premature responding. Behav Brain Res. 2011 Sep 12; 222(1):183-92. Young JW, Powell SB, Scott CN, Zhou X, Geyer MA. PMID: 21458500.
      View in: PubMed   Mentions: 32     Fields:    Translation:Animals
    103. Increased hippocampal accumulation of autophagosomes predicts short-term recognition memory impairment in aged mice. Age (Dordr). 2012 Apr; 34(2):305-16. Soontornniyomkij V, Risbrough VB, Young JW, Soontornniyomkij B, Jeste DV, Achim CL. PMID: 21431350.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    104. Increased risk-taking behavior in dopamine transporter knockdown mice: further support for a mouse model of mania. J Psychopharmacol. 2011 Jul; 25(7):934-43. Young JW, van Enkhuizen J, Winstanley CA, Geyer MA. PMID: 21421642.
      View in: PubMed   Mentions: 35     Fields:    Translation:Animals
    105. Dopamine receptor mediation of the exploratory/hyperactivity effects of modafinil. Neuropsychopharmacology. 2011 Jun; 36(7):1385-96. Young JW, Kooistra K, Geyer MA. PMID: 21412225.
      View in: PubMed   Mentions: 19     Fields:    Translation:Animals
    106. Effect of methamphetamine dependence on inhibitory deficits in a novel human open-field paradigm. Psychopharmacology (Berl). 2011 Jun; 215(4):697-707. Henry BL, Minassian A, van Rhenen M, Young JW, Geyer MA, Perry W. PMID: 21279333.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    107. Working memory span capacity improved by a D2 but not D1 receptor family agonist. Behav Brain Res. 2011 Jun 01; 219(2):181-8. Tarantino IS, Sharp RF, Geyer MA, Meves JM, Young JW. PMID: 21232557.
      View in: PubMed   Mentions: 9     Fields:    Translation:Animals
    108. Initial evidence linking synaptic superoxide production with poor short-term memory in aged mice. Brain Res. 2011 Jan 12; 1368:65-70. Ali SS, Young JW, Wallace CK, Gresack J, Jeste DV, Geyer MA, Dugan LL, Risbrough VB. PMID: 21075081.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    109. Evaluation of the clinical efficacy of asenapine in schizophrenia. Expert Opin Pharmacother. 2010 Aug; 11(12):2107-15. Minassian A, Young JW. PMID: 20642375.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    110. Quantifying over-activity in bipolar and schizophrenia patients in a human open field paradigm. Psychiatry Res. 2010 Jun 30; 178(1):84-91. Perry W, Minassian A, Henry B, Kincaid M, Young JW, Geyer MA. PMID: 20471103.
      View in: PubMed   Mentions: 32     Fields:    Translation:Humans
    111. The mouse attentional-set-shifting task: a method for assaying successful cognitive aging? Cogn Affect Behav Neurosci. 2010 May; 10(2):243-51. Young JW, Powell SB, Geyer MA, Jeste DV, Risbrough VB. PMID: 20498348.
      View in: PubMed   Mentions: 31     Fields:    Translation:Animals
    112. Short-term recognition memory impairment is associated with decreased expression of FK506 binding protein 51 in the aged mouse brain. Age (Dordr). 2010 Sep; 32(3):309-22. Soontornniyomkij V, Risbrough VB, Young JW, Wallace CK, Soontornniyomkij B, Jeste DV, Achim CL. PMID: 20422297.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    113. Cross-species assessments of motor and exploratory behavior related to bipolar disorder. Neurosci Biobehav Rev. 2010 Jul; 34(8):1296-306. Henry BL, Minassian A, Young JW, Paulus MP, Geyer MA, Perry W. PMID: 20398694.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimals
    114. The mania-like exploratory profile in genetic dopamine transporter mouse models is diminished in a familiar environment and reinstated by subthreshold psychostimulant administration. Pharmacol Biochem Behav. 2010 Jul; 96(1):7-15. Young JW, Goey AK, Minassian A, Perry W, Paulus MP, Geyer MA. PMID: 20363246.
      View in: PubMed   Mentions: 28     Fields:    Translation:Animals
    115. Action of modafinil--increased motivation via the dopamine transporter inhibition and D1 receptors? Biol Psychiatry. 2010 Apr 15; 67(8):784-7. Young JW, Geyer MA. PMID: 20132929.
      View in: PubMed   Mentions: 28     Fields:    Translation:Animals
    116. Age-associated improvements in cross-modal prepulse inhibition in mice. Behav Neurosci. 2010 Feb; 124(1):133-140. Young JW, Wallace CK, Geyer MA, Risbrough VB. PMID: 20141288.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    117. The quantitative assessment of motor activity in mania and schizophrenia. J Affect Disord. 2010 Jan; 120(1-3):200-6. Minassian A, Henry BL, Geyer MA, Paulus MP, Young JW, Perry W. PMID: 19435640.
      View in: PubMed   Mentions: 35     Fields:    Translation:Humans
    118. Animal models of schizophrenia. Curr Top Behav Neurosci. 2010; 4:391-433. Young JW, Zhou X, Geyer MA. PMID: 21312408.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimals
    119. GBR 12909 administration as a mouse model of bipolar disorder mania: mimicking quantitative assessment of manic behavior. Psychopharmacology (Berl). 2010 Feb; 208(3):443-54. Young JW, Goey AK, Minassian A, Perry W, Paulus MP, Geyer MA. PMID: 20020109.
      View in: PubMed   Mentions: 35     Fields:    Translation:Animals
    120. A reverse-translational study of dysfunctional exploration in psychiatric disorders: from mice to men. Arch Gen Psychiatry. 2009 Oct; 66(10):1072-80. Perry W, Minassian A, Paulus MP, Young JW, Kincaid MJ, Ferguson EJ, Henry BL, Zhuang X, Masten VL, Sharp RF, Geyer MA. PMID: 19805697.
      View in: PubMed   Mentions: 75     Fields:    Translation:HumansAnimals
    121. Asenapine effects in animal models of psychosis and cognitive function. Psychopharmacology (Berl). 2009 Nov; 206(4):699-714. Marston HM, Young JW, Martin FD, Serpa KA, Moore CL, Wong EH, Gold L, Meltzer LT, Azar MR, Geyer MA, Shahid M. PMID: 19462162.
      View in: PubMed   Mentions: 15     Fields:    Translation:Animals
    122. Using the MATRICS to guide development of a preclinical cognitive test battery for research in schizophrenia. Pharmacol Ther. 2009 May; 122(2):150-202. Young JW, Powell SB, Risbrough V, Marston HM, Geyer MA. PMID: 19269307.
      View in: PubMed   Mentions: 109     Fields:    Translation:HumansAnimals
    123. Dopamine D1 and D2 receptor family contributions to modafinil-induced wakefulness. J Neurosci. 2009 Mar 04; 29(9):2663-5. Young JW. PMID: 19261860.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    124. The 5-choice continuous performance test: evidence for a translational test of vigilance for mice. PLoS One. 2009; 4(1):e4227. Young JW, Light GA, Marston HM, Sharp R, Geyer MA. PMID: 19156216.
      View in: PubMed   Mentions: 59     Fields:    Translation:Animals
    125. Atypical antipsychotics clozapine and quetiapine attenuate prepulse inhibition deficits in dopamine transporter knockout mice. Behav Pharmacol. 2008 Sep; 19(5-6):562-5. Powell SB, Young JW, Ong JC, Caron MG, Geyer MA. PMID: 18690110.
      View in: PubMed   Mentions: 25     Fields:    Translation:Animals
    126. Progressive impairment in olfactory working memory in a mouse model of Mild Cognitive Impairment. Neurobiol Aging. 2009 Sep; 30(9):1430-43. Young JW, Sharkey J, Finlayson K. PMID: 18242780.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimals
    127. A reverse-translational approach to bipolar disorder: rodent and human studies in the Behavioral Pattern Monitor. Neurosci Biobehav Rev. 2007; 31(6):882-96. Young JW, Minassian A, Paulus MP, Geyer MA, Perry W. PMID: 17706782.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansAnimals
    128. The odour span task: a novel paradigm for assessing working memory in mice. Neuropharmacology. 2007 Feb; 52(2):634-45. Young JW, Kerr LE, Kelly JS, Marston HM, Spratt C, Finlayson K, Sharkey J. PMID: 17097694.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimals
    129. Impaired attention is central to the cognitive deficits observed in alpha 7 deficient mice. Eur Neuropsychopharmacol. 2007 Jan 15; 17(2):145-55. Young JW, Crawford N, Kelly JS, Kerr LE, Marston HM, Spratt C, Finlayson K, Sharkey J. PMID: 16650968.
      View in: PubMed   Mentions: 85     Fields:    Translation:AnimalsCells
    130. Nicotine improves sustained attention in mice: evidence for involvement of the alpha7 nicotinic acetylcholine receptor. Neuropsychopharmacology. 2004 May; 29(5):891-900. Young JW, Finlayson K, Spratt C, Marston HM, Crawford N, Kelly JS, Sharkey J. PMID: 14970827.
      View in: PubMed   Mentions: 75     Fields:    Translation:AnimalsCells
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