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Psychometric Evaluation of Cognitive and Positive Valence Tasks Chosen for the NIMH Research Domain Criteria Project. Assessment. 2024 Oct 06; 10731911241280770.
Duffy JR, Sturm ET, Sares AG, Sarabia L, Delao EM, M Becker K, Colmenares AM, Manavi RM, Rojas DC, Tregellas JR, Young JW, Thomas ML. PMID: 39370739.
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PubMed Mentions: Fields:
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Acute nicotine vapor normalizes sensorimotor gating and reduces locomotor activity deficits in HIV-1 transgenic rats. bioRxiv. 2024 Jun 22.
Jha NA, Ayoub SM, Flesher MM, Morton K, Sikkink M, de Guglielmo G, Khokhar JY, Minassian A, Brody AL, Young JW. PMID: 38948796; PMCID: PMC11212989.
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PubMed Mentions:
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The Impact of Cannabis Use on Cognition in People with HIV: Evidence of Function-Dependent Effects and Mechanisms from Clinical and Preclinical Studies. Curr HIV/AIDS Rep. 2024 06; 21(3):87-115.
Ayoub SM, Holloway BM, Miranda AH, Roberts BZ, Young JW, Minassian A, Ellis RJ. PMID: 38602558; PMCID: PMC11129923.
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PubMed Mentions: Fields:
Translation:
HumansAnimals
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Decision-making for delaying punishment? A commentary to Minnes et al. (2024). Cogn Affect Behav Neurosci. 2024 Apr; 24(2):322-324.
Young JW, Roberts BZ. PMID: 38459405.
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PubMed Mentions: Fields:
Translation:
Humans
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Sex differences in risk-based decision-making and the modulation of risk preference by dopamine-2 like receptors in rats. Neuropharmacology. 2024 May 01; 248:109851.
Ayoub SM, Libster AM, Barnes SA, Dulawa SC, Young JW. PMID: 38325772; PMCID: PMC11227321.
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PubMed Mentions: Fields:
Translation:
HumansAnimals
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Amphetamine increases motivation of humans and mice as measured by breakpoint, but does not affect an Electroencephalographic biomarker. Cogn Affect Behav Neurosci. 2024 Apr; 24(2):269-278.
Noback M, Bhakta SG, Talledo JA, Kotz JE, Benster L, Roberts BZ, Nungaray JA, Light GA, Swerdlow NR, Brigman JL, Cavanagh JF, Young JW. PMID: 38168850; PMCID: PMC11060428.
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PubMed Mentions: Fields:
Translation:
HumansAnimals
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30 years of the International Behavioral Neuroscience Society: Perspectives on progress from Past Presidents. Neurosci Biobehav Rev. 2023 Dec; 155:105457.
Young JW. PMID: 37925092.
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PubMed Mentions: Fields:
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Daily mood and cognitive performance of women with and without bipolar disorder: role of menopausal status. Arch Womens Ment Health. 2023 12; 26(6):863-868.
Liu Y, Ng HX, Klaus F, Young JW, Eyler LT. PMID: 37667089; PMCID: PMC10632205.
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PubMed Mentions: Fields:
Translation:
Humans
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The Role of Cannabis and The Endocannabinoid System in Sleep Regulation and Cognition: A Review of Human and Animal Studies. Behav Sleep Med. 2024 Mar 03; 22(2):217-233.
Miranda A, Peek E, Ancoli-Israel S, Young JW, Perry W, Minassian A. PMID: 37401160; PMCID: PMC10761597.
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PubMed Mentions: Fields:
Translation:
HumansAnimals
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Impaired cognitive control after moderate prenatal alcohol exposure corresponds to altered EEG power during a rodent touchscreen continuous performance task. Neuropharmacology. 2023 Sep 15; 236:109599.
Olguin SL, Cavanagh JF, Young JW, Brigman JL. PMID: 37217074; PMCID: PMC10330662.
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PubMed Mentions:
2 Fields:
Translation:
HumansAnimals
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CADM2 is implicated in impulsive personality and numerous other traits by genome- and phenome-wide association studies in humans and mice. Transl Psychiatry. 2023 05 12; 13(1):167.
Sanchez-Roige S, Jennings MV, Thorpe HHA, Mallari JE, van der Werf LC, Bianchi SB, Huang Y, Lee C, Mallard TT, Barnes SA, Wu JY, Barkley-Levenson AM, Boussaty EC, Snethlage CE, Schafer D, Babic Z, Winters BD, Watters KE, Biederer T, 23andMe Research Team, Mackillop J, Stephens DN, Elson SL, Fontanillas P, Khokhar JY, Young JW, Palmer AA. PMID: 37173343; PMCID: PMC10182097.
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PubMed Mentions:
18 Fields:
Translation:
HumansAnimals
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Modulation of ventromedial orbitofrontal cortical glutamatergic activity affects the explore-exploit balance and influences value-based decision-making. Cereb Cortex. 2023 05 09; 33(10):5783-5796.
Barnes SA, Dillon DG, Young JW, Thomas ML, Faget L, Yoo JH, Der-Avakian A, Hnasko TS, Geyer MA, Ramanathan DS. PMID: 36472411; PMCID: PMC10183731.
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PubMed Mentions:
1 Fields:
Translation:
Animals
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Perspective on equitable translational studies and clinical support for an unbiased inclusion of the LGBTQIA2S+community. Neuropsychopharmacology. 2023 05; 48(6):852-856.
Goetz TG, Aghi K, Anacker C, Ehrensaft D, Eshel N, Marrocco J, Young JW, Roepke TA. PMID: 36928352; PMCID: PMC10156811.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Development of cross-species translational paradigms for psychiatric research in the Research Domain Criteria era. Neurosci Biobehav Rev. 2023 05; 148:105119.
Young JW. PMID: 36889561.
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PubMed Mentions:
1 Fields:
Translation:
Animals
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Short-active gestational photoperiod reduces effortful choice behavior in mice, partial normalization by d-amphetamine. Psychopharmacology (Berl). 2023 Nov; 240(11):2303-2315.
Roberts BZ, O'Connor MA, Kenton JA, Barnes SA, Young JW. PMID: 36806900.
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PubMed Mentions: Fields:
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A Pilot Assessment of the Effects of HIV and Methamphetamine Dependence on Socially Dysregulated Behavior in the Human Behavioral Pattern Monitor. AIDS Behav. 2023 Aug; 27(8):2617-2628.
Miranda A, Perry W, Umlauf A, Young JW, Morgan EE, Minassian A, Translational Methamphetamine AIDS Research Center (TMARC). PMID: 36738342; PMCID: PMC9898694.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Reinforcement learning deficits exhibited by postnatal PCP-treated rats enable deep neural network classification. Neuropsychopharmacology. 2023 08; 48(9):1377-1385.
Tranter MM, Aggarwal S, Young JW, Dillon DG, Barnes SA. PMID: 36509858; PMCID: PMC10354061.
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PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
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Translational cognitive systems: focus on attention. Emerg Top Life Sci. 2022 12 09; 6(5):529-539.
Roberts BZ, Young JW. PMID: 36408755.
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PubMed Mentions:
5 Fields:
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iTat transgenic mice exhibit hyper-locomotion in the behavioral pattern monitor after chronic exposure to methamphetamine but are unaffected by Tat expression. Pharmacol Biochem Behav. 2023 01; 222:173499.
Ayoub S, Kenton JA, Milienne-Petiot M, Deben DS, Achim C, Geyer MA, Perry W, Grant IE, Young JW, Minassian A, TMARC. PMID: 36462584; PMCID: PMC10014034.
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PubMed Mentions:
2 Fields:
Translation:
HumansAnimals
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The interplay of daily affect and impulsivity measured by mobile surveys in bipolar disorder. Int J Bipolar Disord. 2022 Oct 31; 10(1):25.
Titone MK, Depp C, Klaus F, Carrasco J, Young JW, Eyler LT. PMID: 36310294; PMCID: PMC9618470.
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PubMed Mentions:
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Chronic methamphetamine exposure exerts few effects on the iTat mouse model of HIV, but blocks Tat expression-induced slowed reward retrieval. Behav Brain Res. 2023 02 02; 437:114109.
Young JW, Kenton JA, Milienne-Petiot M, Deben D, Achim C, Geyer MA, Perry W, Grant IE, Minassian A, TMARC. PMID: 36108778; PMCID: PMC10878174.
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PubMed Mentions: Fields:
Translation:
HumansAnimals
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The relationship between novelty-seeking traits and behavior: Establishing construct validity for the human Behavioral Pattern Monitor. Psychiatry Res. 2022 10; 316:114776.
Minassian A, Kelsoe JR, Miranda A, Young JW, Perry W. PMID: 35964417; PMCID: PMC9885942.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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The 2020 International Behavioral Neuroscience Society (IBNS) meeting - Troubles & progress. Neurosci Biobehav Rev. 2022 12; 143:104819.
Young JW, Byrnes EM. PMID: 35940308; PMCID: PMC9354388.
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PubMed Mentions: Fields:
Translation:
Humans
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Correction to: Electrophysiological biomarkers of behavioral dimensions from cross-species paradigms. Transl Psychiatry. 2022 Jul 21; 12(1):290.
Cavanagh JF, Gregg D, Light GA, Olguin SL, Sharp RF, Bismark AW, Bhakta SG, Swerdlow NR, Brigman JL, Young JW. PMID: 35864090; PMCID: PMC9304120.
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PubMed Mentions: Fields:
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Combined prior chronic methamphetamine treatment and gp120 expression reduce PPI in aged male but not female mice. Neurosci Lett. 2022 05 29; 780:136639.
Jordan Walter T, Minassian A, Perry W, Young JW, Translational Methamphetamine AIDS Research Center (TMARC). PMID: 35452766.
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PubMed Mentions:
2 Fields:
Translation:
HumansAnimals
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Amphetamine alters an EEG marker of reward processing in humans and mice. Psychopharmacology (Berl). 2022 Mar; 239(3):923-933.
Cavanagh JF, Olguin SL, Talledo JA, Kotz JE, Roberts BZ, Nungaray JA, Sprock J, Gregg D, Bhakta SG, Light GA, Swerdlow NR, Young JW, Brigman JL. PMID: 35132440; PMCID: PMC8891070.
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PubMed Mentions:
7 Fields:
Translation:
HumansAnimals
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MicroPET evidence for a hypersensitive neuroinflammatory profile of gp120 mouse model of HIV. Psychiatry Res Neuroimaging. 2022 04; 321:111445.
Young JW, Barback CV, Stolz LA, Groman SM, Vera DR, Hoh C, Kotta KK, Minassian A, Powell SB, Brody AL. PMID: 35101828.
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PubMed Mentions:
3 Fields:
Translation:
HumansAnimals
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EEG reveals that dextroamphetamine improves cognitive control through multiple processes in healthy participants. Neuropsychopharmacology. 2022 04; 47(5):1029-1036.
Bhakta SG, Cavanagh JF, Talledo JA, Kotz JE, Benster L, Roberts BZ, Nungaray JA, Brigman JL, Light GA, Swerdlow NR, Young JW. PMID: 35042948; PMCID: PMC8938448.
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PubMed Mentions:
3 Fields:
Translation:
Humans
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Preclinical Evaluation of Attention and Impulsivity Relevant to Determining ADHD Mechanisms and Treatments. Curr Top Behav Neurosci. 2022; 57:291-320.
Kenton JA, Young JW. PMID: 35606639.
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PubMed Mentions: Fields:
Translation:
HumansAnimals
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HIV Transgenic Rats Demonstrate Impaired Sensorimotor Gating But Are Insensitive to Cannabinoid (Δ9-Tetrahydrocannabinol)-Induced Deficits. Int J Neuropsychopharmacol. 2021 11 12; 24(11):894-906.
Roberts BZ, Minassian A, Halberstadt AL, He YV, Chatha M, Geyer MA, Grant I, Young JW. PMID: 34338765; PMCID: PMC8598295.
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PubMed Mentions:
3 Fields:
Translation:
Animals
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Electrophysiological biomarkers of behavioral dimensions from cross-species paradigms. Transl Psychiatry. 2021 09 17; 11(1):482.
Cavanagh JF, Gregg D, Light GA, Olguin SL, Sharp RF, Bismark AW, Bhakta SG, Swerdlow NR, Brigman JL, Young JW. PMID: 34535625; PMCID: PMC8448772.
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PubMed Mentions:
11 Fields:
Translation:
Animals
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HIV Transgenic Rats Demonstrate Superior Task Acquisition and Intact Reversal Learning in the Within-Session Probabilistic Reversal Learning Task. Cogn Affect Behav Neurosci. 2021 12; 21(6):1207-1221.
Roberts BZ, He YV, Chatha M, Minassian A, Grant I, Young JW. PMID: 34312815; PMCID: PMC9815827.
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PubMed Mentions:
2 Fields:
Translation:
Animals
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The Effects of Cannabis Use on Cognitive Function in Healthy Aging: A Systematic Scoping Review. Arch Clin Neuropsychol. 2021 Jul 19; 36(5):673-685.
Pocuca N, Walter TJ, Minassian A, Young JW, Geyer MA, Perry W. PMID: 33159510; PMCID: PMC8296849.
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PubMed Mentions:
7 Fields:
Translation:
Animals
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The Relationships between HIV-1 Infection, History of Methamphetamine Use Disorder, and Soluble Biomarkers in Blood and Cerebrospinal Fluid. Viruses. 2021 07 01; 13(7).
Walter TJ, Iudicello J, Cookson DR, Franklin D, Tang B, Young JW, Perry W, Ellis R, Heaton RK, Grant I, Minassian A, Letendre S. PMID: 34372493; PMCID: PMC8310127.
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PubMed Mentions:
4 Fields:
Translation:
HumansCells
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Chronic antipsychotic treatment exerts limited effects on the mania-like behavior of dopamine transporter knockdown mice. Behav Brain Res. 2021 05 07; 405:113167.
Cope ZA, Kenton JA, Minassian A, Martin MV, Perry W, Bundgaard C, Arnt J, van Enkhuizen J, Geyer MA, Young JW. PMID: 33577882; PMCID: PMC10729608.
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PubMed Mentions:
1 Fields:
Translation:
Animals
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Convergent observations of MK-801-induced impairment in rat 5C-CPT performance across laboratories: reversal with a D1 but not nicotinic agonist. Psychopharmacology (Berl). 2021 Apr; 238(4):979-990.
Grottick AJ, MacQueen DL, Barnes SA, Carroll C, Sanabria EK, Bobba V, Young JW. PMID: 33404734.
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PubMed Mentions:
1 Fields:
Translation:
Animals
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The relationship between cannabis use and cognition in people with bipolar disorder: A systematic scoping review. Psychiatry Res. 2021 03; 297:113695.
Jordan Walter T, Pocuca N, Young JW, Geyer MA, Minassian A, Perry W. PMID: 33545431; PMCID: PMC7914198.
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PubMed Mentions:
3 Fields:
Translation:
Humans
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Converging evidence that short-active photoperiod increases acetylcholine signaling in the hippocampus. Cogn Affect Behav Neurosci. 2020 12; 20(6):1173-1183.
Cope ZA, Lavadia ML, Joosen AJM, van de Cappelle CJA, Lara JC, Huval A, Kwiatkowski MK, Picciotto MR, Mineur YS, Dulcis D, Young JW. PMID: 32794101; PMCID: PMC7718303.
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PubMed Mentions:
5 Fields:
Translation:
Animals
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Chronic nicotine, but not suramin or resveratrol, partially remediates the mania-like profile of dopamine transporter knockdown mice. Eur Neuropsychopharmacol. 2021 01; 42:75-86.
Kwiatkowski MA, Roberts BZ, van Enkhuizen J, Ji B, Zhou X, Young JW. PMID: 33191077; PMCID: PMC8853461.
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PubMed Mentions:
1 Fields:
Translation:
HumansAnimals
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Both HIV and Tat expression decrease prepulse inhibition with further impairment by methamphetamine. Prog Neuropsychopharmacol Biol Psychiatry. 2021 03 02; 106:110089.
Walter TJ, Young JW, Milienne-Petiot M, Deben DS, Heaton RK, Letendre S, Grelotti DJ, Perry W, Grant I, Minassian A, Translational Methamphetamine AIDS Research Center (TMARC). PMID: 32891668; PMCID: PMC7750302.
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PubMed Mentions:
6 Fields:
Translation:
HumansAnimalsCells
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Sustained attention and vigilance deficits associated with HIV and a history of methamphetamine dependence. Drug Alcohol Depend. 2020 10 01; 215:108245.
Pocuca N, Young JW, MacQueen DA, Letendre S, Heaton RK, Geyer MA, Perry W, Grant I, Minassian A, Translational Methamphetamine AIDS Research Center (TMARC). PMID: 32871507; PMCID: PMC7811354.
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PubMed Mentions:
5 Fields:
Translation:
Humans
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Short-active photoperiod gestation induces psychiatry-relevant behavior in healthy mice but a resiliency to such effects are seen in mice with reduced dopamine transporter expression. Sci Rep. 2020 06 23; 10(1):10217.
Kwiatkowski MA, Cope ZA, Lavadia ML, van de Cappelle CJA, Dulcis D, Young JW. PMID: 32576854; PMCID: PMC7311429.
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PubMed Mentions:
2 Fields:
Translation:
Animals
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Amphetamine improves rat 5-choice continuous performance test (5C-CPT) irrespective of concurrent low-dose haloperidol treatment. Psychopharmacology (Berl). 2020 Jul; 237(7):1959-1972.
Young JW, Roberts BZ, Breier M, Swerdlow NR. PMID: 32318751.
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PubMed Mentions:
6 Fields:
Translation:
Animals
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Moderate prenatal alcohol exposure impairs cognitive control, but not attention, on a rodent touchscreen continuous performance task. Genes Brain Behav. 2021 01; 20(1):e12652.
Olguin SL, Thompson SM, Young JW, Brigman JL. PMID: 32144885; PMCID: PMC8128045.
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PubMed Mentions:
18 Fields:
Translation:
Animals
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The D2-family receptor agonist bromocriptine but, not nicotine, reverses NMDA receptor antagonist-induced working memory deficits in the radial arm maze in mice. Neurobiol Learn Mem. 2020 02; 168:107159.
MacQueen DA, Young JW. PMID: 31911198.
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PubMed Mentions:
1 Fields:
Translation:
Animals
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Btbd3 expression regulates compulsive-like and exploratory behaviors in mice. Transl Psychiatry. 2019 09 09; 9(1):222.
Thompson SL, Welch AC, Ho EV, Bessa JM, Portugal-Nunes C, Morais M, Young JW, Knowles JA, Dulawa SC. PMID: 31501410; PMCID: PMC6733800.
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PubMed Mentions:
7 Fields:
Translation:
Animals
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Reconsidering the Latent Structure of Negative Symptoms in Schizophrenia: A Review of Evidence Supporting the 5 Consensus Domains. Schizophr Bull. 2019 06 18; 45(4):725-729.
Strauss GP, Ahmed AO, Young JW, Kirkpatrick B. PMID: 30541136; PMCID: PMC6581128.
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PubMed Mentions:
35 Fields:
Translation:
Humans
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Current status of the neurobiology of aggression and impulsivity. Neuropharmacology. 2019 09 15; 156:107665.
Slattery DA, Young JW. PMID: 31176758.
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PubMed Mentions: Fields:
Translation:
HumansAnimals
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Convergent neural substrates of inattention in bipolar disorder patients and dopamine transporter-deficient mice using the 5-choice CPT. Bipolar Disord. 2020 02; 22(1):46-58.
Young JW, Geyer MA, Halberstadt AL, van Enkhuizen J, Minassian A, Khan A, Perry W, Eyler LT. PMID: 31025493; PMCID: PMC6815232.
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PubMed Mentions:
14 Fields:
Translation:
HumansAnimalsCells
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Oxytocin improves probabilistic reversal learning but not effortful motivation in Brown Norway rats. Neuropharmacology. 2019 05 15; 150:15-26.
Roberts BZ, Young JW, He YV, Cope ZA, Shilling PD, Feifel D. PMID: 30844406; PMCID: PMC6500730.
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PubMed Mentions:
11 Fields:
Translation:
Animals
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The importance and depth of reproducibility in rodent models of psychiatric diseases. Pharmacol Biochem Behav. 2019 03; 178:1-2.
Young JW, Einat H. PMID: 30777154.
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PubMed Mentions: Fields:
Translation:
Animals
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Evidence for light-entrainment-induced switching between depression- & mania-relevant behaviors in mice. Neuropsychopharmacology. 2019 09; 44(10):1679-1680.
Young JW, Cope ZA, Romoli B, Schrurs E, Joosen A, van Enkhuizen J, Sharp RF, Dulcis D. PMID: 30787425; PMCID: PMC6784984.
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PubMed Mentions:
2 Fields:
Translation:
Animals
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Nicotine improves probabilistic reward learning in wildtype but not alpha7 nAChR null mutants, yet alpha7 nAChR agonists do not improve probabilistic learning. Eur Neuropsychopharmacol. 2018 11; 28(11):1217-1231.
Milienne-Petiot M, Higa KK, Grim A, Deben D, Groenink L, Twamley EW, Geyer MA, Young JW. PMID: 30213668; PMCID: PMC6344043.
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PubMed Mentions:
2 Fields:
Translation:
Animals
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Amphetamine improves mouse and human attention in the 5-choice continuous performance test. Neuropharmacology. 2018 08; 138:87-96.
MacQueen DA, Minassian A, Kenton JA, Geyer MA, Perry W, Brigman JL, Young JW. PMID: 29859849; PMCID: PMC6340711.
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PubMed Mentions:
23 Fields:
Translation:
HumansAnimals
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Correction to: The Effects of Cariprazine and Aripiprazole on PCP-Induced Deficits on Attention Assessed in the 5-Choice Serial Reaction Time Task. Psychopharmacology (Berl). 2018 05; 235(5):1621.
Barnes SA, Young JW, Markou A, Adham N, Gyertyán I, Kiss B. PMID: 29564481; PMCID: PMC6713673.
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PubMed Mentions:
1 Fields:
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Reverse translated and gold standard continuous performance tests predict global cognitive performance in schizophrenia. Transl Psychiatry. 2018 04 12; 8(1):80.
Bismark AW, Thomas ML, Tarasenko M, Shiluk AL, Rackelmann SY, Young JW, Light GA. PMID: 29643355; PMCID: PMC5895589.
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PubMed Mentions:
3 Fields:
Translation:
Humans
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Mice with reduced DAT levels recreate seasonal-induced switching between states in bipolar disorder. Neuropsychopharmacology. 2018 07; 43(8):1721-1731.
Young JW, Cope ZA, Romoli B, Schrurs E, van Enkhuizen J, Sharp RF, Dulcis D. PMID: 29520059; PMCID: PMC6006292.
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PubMed Mentions:
21 Fields:
Translation:
AnimalsCells
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The Effects of Cariprazine and Aripiprazole on PCP-Induced Deficits on Attention Assessed in the 5-Choice Serial Reaction Time Task. Psychopharmacology (Berl). 2018 05; 235(5):1403-1414.
Barnes SA, Young JW, Markou A, Adham N, Gyertyán I, Kiss B. PMID: 29473089; PMCID: PMC5920008.
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PubMed Mentions:
7 Fields:
Translation:
Animals
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Cross-Species Neurophysiological Biomarkers of Attentional Dysfunction in Schizophrenia: Bridging the Translational Gap. Neuropsychopharmacology. 2018 01; 43(1):230-231.
Young JW, Light GA. PMID: 29192660; PMCID: PMC5719116.
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PubMed Mentions:
2 Fields:
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Cognitive Phenotypes for Biomarker Identification in Mental Illness: Forward and Reverse Translation. Curr Top Behav Neurosci. 2018; 40:111-166.
MacQueen DA, Young JW, Cope ZA. PMID: 29858983.
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PubMed Mentions: Fields:
Translation:
Humans
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Dopamine transporter knockdown mice in the behavioral pattern monitor: A robust, reproducible model for mania-relevant behaviors. Pharmacol Biochem Behav. 2019 03; 178:42-50.
Kwiatkowski MA, Hellemann G, Sugar CA, Cope ZA, Minassian A, Perry W, Geyer MA, Young JW. PMID: 29289701; PMCID: PMC10014035.
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PubMed Mentions:
10 Fields:
Translation:
Animals
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Tolcapone-Enhanced Neurocognition in Healthy Adults: Neural Basis and Predictors. Int J Neuropsychopharmacol. 2017 12 01; 20(12):979-987.
Bhakta SG, Light GA, Talledo JA, Balvaneda B, Hughes E, Alvarez A, Rana BK, Young JW, Swerdlow NR. PMID: 29020372; PMCID: PMC5716101.
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PubMed Mentions:
9 Fields:
Translation:
Humans
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Phencyclidine increased while isolation rearing did not affect progressive ratio responding in rats: Investigating potential models of amotivation in schizophrenia. Behav Brain Res. 2019 05 17; 364:413-422.
Amitai N, Powell SB, Young JW. PMID: 29175446.
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PubMed Mentions:
5 Fields:
Translation:
Animals
-
View in:
PubMed Mentions:
4
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Transgenic mice expressing HIV-1 envelope protein gp120 in the brain as an animal model in neuroAIDS research. J Neurovirol. 2018 04; 24(2):156-167.
Thaney VE, Sanchez AB, Fields JA, Minassian A, Young JW, Maung R, Kaul M. PMID: 29075998; PMCID: PMC5911244.
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PubMed Mentions:
31 Fields:
Translation:
AnimalsCells
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Amphetamine Modestly Improves Conners' Continuous Performance Test Performance in Healthy Adults. J Int Neuropsychol Soc. 2018 03; 24(3):283-293.
MacQueen DA, Minassian A, Henry BL, Geyer MA, Young JW, Perry W. PMID: 29032769; PMCID: PMC5820221.
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PubMed Mentions:
11 Fields:
Translation:
Humans
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Blockade of dopamine D1-family receptors attenuates the mania-like hyperactive, risk-preferring, and high motivation behavioral profile of mice with low dopamine transporter levels. J Psychopharmacol. 2017 10; 31(10):1334-1346.
Milienne-Petiot M, Groenink L, Minassian A, Young JW. PMID: 28950781; PMCID: PMC10773978.
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PubMed Mentions:
7 Fields:
Translation:
Animals
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Modafinil improves attentional performance in healthy, non-sleep deprived humans at doses not inducing hyperarousal across species. Neuropharmacology. 2017 Oct; 125:254-262.
Cope ZA, Minassian A, Kreitner D, MacQueen DA, Milienne-Petiot M, Geyer MA, Perry W, Young JW. PMID: 28774856; PMCID: PMC6472902.
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PubMed Mentions:
10 Fields:
Translation:
HumansAnimals
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The 5 choice continuous performance test (5C-CPT): A novel tool to assess cognitive control across species. J Neurosci Methods. 2017 Dec 01; 292:53-60.
Bhakta SG, Young JW. PMID: 28754432; PMCID: PMC5813688.
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PubMed Mentions:
8 Fields:
Translation:
HumansAnimals
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Preclinical Models to Investigate Mechanisms of Negative Symptoms in Schizophrenia. Schizophr Bull. 2017 07 01; 43(4):706-711.
Barnes SA, Der-Avakian A, Young JW. PMID: 28586462; PMCID: PMC5472160.
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PubMed Mentions:
11 Fields:
Translation:
HumansAnimals
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Relationship between effortful motivation and neurocognition in schizophrenia. Schizophr Res. 2018 03; 193:69-76.
Bismark AW, Thomas ML, Tarasenko M, Shiluk AL, Rackelmann SY, Young JW, Light GA. PMID: 28673753; PMCID: PMC5754266.
View in:
PubMed Mentions:
26 Fields:
Translation:
Humans
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Introduction to the special issue from the 2015 meeting of the International Behavioral Neuroscience Society. Neurosci Biobehav Rev. 2017 05; 76(Pt B):185-186.
Pletnikov M, Young JW, Hall FS, Kent S. PMID: 28300550.
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Humans
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Brexpiprazole reduces hyperactivity, impulsivity, and risk-preference behavior in mice with dopamine transporter knockdown-a model of mania. Psychopharmacology (Berl). 2017 Mar; 234(6):1017-1028.
Milienne-Petiot M, Geyer MA, Arnt J, Young JW. PMID: 28160035; PMCID: PMC5391249.
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PubMed Mentions:
10 Fields:
Translation:
Animals
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Striatal dopamine D1 receptor suppression impairs reward-associative learning. Behav Brain Res. 2017 04 14; 323:100-110.
Higa KK, Young JW, Ji B, Nichols DE, Geyer MA, Zhou X. PMID: 28143767.
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PubMed Mentions:
12 Fields:
Translation:
Animals
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The Five-Choice Continuous Performance Task (5C-CPT): A Cross-Species Relevant Paradigm for Assessment of Vigilance and Response Inhibition in Rodents. Curr Protoc Neurosci. 2017 01 03; 78:9.56.1-9.56.18.
Cope ZA, Young JW. PMID: 28046200; PMCID: PMC6472906.
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PubMed Mentions:
11 Fields:
Translation:
Animals
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Neurophysiological Characterization of Attentional Performance Dysfunction in Schizophrenia Patients in a Reverse-Translated Task. Neuropsychopharmacology. 2017 May; 42(6):1338-1348.
Young JW, Bismark AW, Sun Y, Zhang W, McIlwain M, Grootendorst I, Light GA. PMID: 27917869; PMCID: PMC5437886.
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PubMed Mentions:
16 Fields:
Translation:
Humans
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Adolescent GBR12909 exposure induces oxidative stress, disrupts parvalbumin-positive interneurons, and leads to hyperactivity and impulsivity in adult mice. Neuroscience. 2017 03 14; 345:166-175.
Khan A, de Jong LA, Kamenski ME, Higa KK, Lucero JD, Young JW, Behrens MM, Powell SB. PMID: 27890827; PMCID: PMC5316310.
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PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
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Research Domain Criteria versus DSM V: How does this debate affect attempts to model corticostriatal dysfunction in animals? Neurosci Biobehav Rev. 2017 05; 76(Pt B):301-316.
Young JW, Winstanley CA, Brady AM, Hall FS. PMID: 27826070.
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PubMed Mentions:
10 Fields:
Translation:
Humans
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The effects of reduced dopamine transporter function and chronic lithium on motivation, probabilistic learning, and neurochemistry in mice: Modeling bipolar mania. Neuropharmacology. 2017 02; 113(Pt A):260-270.
Milienne-Petiot M, Kesby JP, Graves M, van Enkhuizen J, Semenova S, Minassian A, Markou A, Geyer MA, Young JW. PMID: 27732870; PMCID: PMC5148687.
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PubMed Mentions:
19 Fields:
Translation:
Animals
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Premature responses in the five-choice serial reaction time task reflect rodents' temporal strategies: evidence from no-light and pharmacological challenges. Psychopharmacology (Berl). 2016 Oct; 233(19-20):3513-25.
Cope ZA, Halberstadt AL, van Enkhuizen J, Flynn AD, Breier M, Swerdlow NR, Geyer MA, Young JW. PMID: 27534540; PMCID: PMC5023490.
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PubMed Mentions:
27 Fields:
Translation:
Animals
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Perseveration by NK1R-/- ('knockout') mice is blunted by doses of methylphenidate that affect neither other aspects of their cognitive performance nor the behaviour of wild-type mice in the 5-Choice Continuous Performance Test. J Psychopharmacol. 2016 09; 30(9):837-47.
Pillidge K, Porter AJ, Young JW, Stanford SC. PMID: 27097734; PMCID: PMC4994704.
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PubMed Mentions:
7 Fields:
Translation:
Animals
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The mood stabilizer valproic acid opposes the effects of dopamine on circadian rhythms. Neuropharmacology. 2016 08; 107:262-270.
Landgraf D, Joiner WJ, McCarthy MJ, Kiessling S, Barandas R, Young JW, Cermakian N, Welsh DK. PMID: 27033596.
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PubMed Mentions:
22 Fields:
Translation:
HumansAnimalsCells
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Effect of 5-HT2A and 5-HT2C receptors on temporal discrimination by mice. Neuropharmacology. 2016 08; 107:364-375.
Halberstadt AL, Sindhunata IS, Scheffers K, Flynn AD, Sharp RF, Geyer MA, Young JW. PMID: 27020041; PMCID: PMC5403251.
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PubMed Mentions:
20 Fields:
Translation:
Animals
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Wet or dry: translatable "water mazes" for mice and humans. J Clin Invest. 2016 Feb; 126(2):477-9.
Higa KK, Young JW, Geyer MA. PMID: 26784538; PMCID: PMC4731183.
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Translation:
HumansAnimals
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Locomotor Profiling from Rodents to the Clinic and Back Again. Curr Top Behav Neurosci. 2016; 28:287-303.
Young JW, Minassian A, Geyer MA. PMID: 27418071.
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PubMed Mentions:
11 Fields:
Translation:
HumansAnimals
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Dispatches from the International Behavioral Neuroscience Society meeting 2014. Introduction. Behav Brain Res. 2015 Dec 15; 295:1-2.
Brigman JL, Young JW, Pletnikov M, Kent S. PMID: 26549148.
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PubMed Mentions: Fields:
Translation:
HumansAnimals
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Negative visuospatial priming in isolation-reared rats: Evidence of resistance to the disruptive effects of amphetamine. Cogn Affect Behav Neurosci. 2015 Dec; 15(4):901-14.
Amitai N, Powell S, Weber M, Swerdlow NR, Young JW. PMID: 26220402; PMCID: PMC4641795.
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PubMed Mentions:
1 Fields:
Translation:
Animals
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Differences in the performance of NK1R-/- ('knockout') and wildtype mice in the 5‑Choice Continuous Performance Test. Behav Brain Res. 2016 Feb 01; 298(Pt B):268-77.
Porter AJ, Pillidge K, Stanford SC, Young JW. PMID: 26522842; PMCID: PMC4683099.
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PubMed Mentions:
8 Fields:
Translation:
Animals
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Introduction to the special issue from the 2014 meeting of the International Behavioral Neuroscience Society. Neurosci Biobehav Rev. 2015 Nov; 58:1-3.
Young JW, Hall FS, Pletnikov M, Kent S. PMID: 26672720.
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PubMed Mentions: Fields:
Translation:
Humans
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View in:
PubMed Mentions:
18 Fields:
Translation:
HumansAnimals
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Investigating the underlying mechanisms of aberrant behaviors in bipolar disorder from patients to models: Rodent and human studies. Neurosci Biobehav Rev. 2015 Nov; 58:4-18.
van Enkhuizen J, Geyer MA, Minassian A, Perry W, Henry BL, Young JW. PMID: 26297513; PMCID: PMC4684462.
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PubMed Mentions:
13 Fields:
Translation:
HumansAnimals
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Effort-Based Decision-Making Paradigms for Clinical Trials in Schizophrenia: Part 2—External Validity and Correlates. Schizophr Bull. 2015 Sep; 41(5):1055-65.
Horan WP, Reddy LF, Barch DM, Buchanan RW, Dunayevich E, Gold JM, Marder SR, Wynn JK, Young JW, Green MF. PMID: 26209546; PMCID: PMC4535650.
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PubMed Mentions:
56 Fields:
Translation:
Humans
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Translational Rodent Paradigms to Investigate Neuromechanisms Underlying Behaviors Relevant to Amotivation and Altered Reward Processing in Schizophrenia. Schizophr Bull. 2015 Sep; 41(5):1024-34.
Young JW, Markou A. PMID: 26194891; PMCID: PMC4535652.
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PubMed Mentions:
28 Fields:
Translation:
HumansAnimals
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Modeling bipolar disorder in mice by increasing acetylcholine or dopamine: chronic lithium treats most, but not all features. Psychopharmacology (Berl). 2015 Sep; 232(18):3455-67.
van Enkhuizen J, Milienne-Petiot M, Geyer MA, Young JW. PMID: 26141192; PMCID: PMC4537820.
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PubMed Mentions:
18 Fields:
Translation:
Animals
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Effort-Based Decision-Making Paradigms for Clinical Trials in Schizophrenia: Part 1—Psychometric Characteristics of 5 Paradigms. Schizophr Bull. 2015 Sep; 41(5):1045-54.
Reddy LF, Horan WP, Barch DM, Buchanan RW, Dunayevich E, Gold JM, Lyons N, Marder SR, Treadway MT, Wynn JK, Young JW, Green MF. PMID: 26142081; PMCID: PMC4535649.
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PubMed Mentions:
72 Fields:
Translation:
Humans
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Neural mechanisms regulating different forms of risk-related decision-making: Insights from animal models. Neurosci Biobehav Rev. 2015 Nov; 58:147-67.
Orsini CA, Moorman DE, Young JW, Setlow B, Floresco SB. PMID: 26072028; PMCID: PMC7913606.
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PubMed Mentions:
78 Fields:
Translation:
HumansAnimals
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Negative affective states and cognitive impairments in nicotine dependence. Neurosci Biobehav Rev. 2015 Nov; 58:168-85.
Hall FS, Der-Avakian A, Gould TJ, Markou A, Shoaib M, Young JW. PMID: 26054790; PMCID: PMC4670824.
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PubMed Mentions:
34 Fields:
Translation:
Humans
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Restoration of Sp4 in Forebrain GABAergic Neurons Rescues Hypersensitivity to Ketamine in Sp4 Hypomorphic Mice. Int J Neuropsychopharmacol. 2015 Jun 02; 18(11):pyv063.
Higa KK, Ji B, Buell MR, Risbrough VB, Powell SB, Young JW, Geyer MA, Zhou X. PMID: 26037489; PMCID: PMC4756721.
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PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
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Early Adolescent Emergence of Reversal Learning Impairments in Isolation-Reared Rats. Dev Neurosci. 2015; 37(3):253-62.
Powell SB, Khan A, Young JW, Scott CN, Buell MR, Caldwell S, Tsan E, de Jong LA, Acheson DT, Lucero J, Geyer MA, Behrens MM. PMID: 26022788; PMCID: PMC4644772.
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PubMed Mentions:
15 Fields:
Translation:
Animals
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GlyT-1 Inhibition Attenuates Attentional But Not Learning or Motivational Deficits of the Sp4 Hypomorphic Mouse Model Relevant to Psychiatric Disorders. Neuropsychopharmacology. 2015 Nov; 40(12):2715-26.
Young JW, Kamenski ME, Higa KK, Light GA, Geyer MA, Zhou X. PMID: 25907107; PMCID: PMC4864647.
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PubMed Mentions:
21 Fields:
Translation:
Animals
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Investigating the mechanism(s) underlying switching between states in bipolar disorder. Eur J Pharmacol. 2015 Jul 15; 759:151-62.
Young JW, Dulcis D. PMID: 25814263; PMCID: PMC4437855.
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PubMed Mentions:
29 Fields:
Translation:
HumansAnimals
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Translational and Early Phase Strategies for Treatment Development: Report of ISCTM Autumn 2013 Symposium. Innov Clin Neurosci. 2015 Mar-Apr; 12(3-4):5S-10S.
Young JW, Potter WZ, Riley S, Groeneveld GJ, Kinon BJ, Egan MF, Feltner DE. PMID: 25977839; PMCID: PMC4571292.
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PubMed Mentions:
1
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Methamphetamine Exposure Combined with HIV-1 Disease or gp120 Expression: Comparison of Learning and Executive Functions in Humans and Mice. Neuropsychopharmacology. 2015 Jul; 40(8):1899-909.
Kesby JP, Heaton RK, Young JW, Umlauf A, Woods SP, Letendre SL, Markou A, Grant I, Semenova S. PMID: 25652249; PMCID: PMC4839513.
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PubMed Mentions:
30 Fields:
Translation:
HumansAnimals
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Developing treatments for cognitive deficits in schizophrenia: the challenge of translation. J Psychopharmacol. 2015 Feb; 29(2):178-96.
Young JW, Geyer MA. PMID: 25516372; PMCID: PMC4670265.
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PubMed Mentions:
52 Fields:
Translation:
HumansAnimals
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The catecholaminergic-cholinergic balance hypothesis of bipolar disorder revisited. Eur J Pharmacol. 2015 Apr 15; 753:114-26.
van Enkhuizen J, Janowsky DS, Olivier B, Minassian A, Perry W, Young JW, Geyer MA. PMID: 25107282; PMCID: PMC4318788.
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PubMed Mentions:
38 Fields:
Translation:
HumansAnimals
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Reduced dopamine transporter functioning induces high-reward risk-preference consistent with bipolar disorder. Neuropsychopharmacology. 2014 Dec; 39(13):3112-22.
van Enkhuizen J, Henry BL, Minassian A, Perry W, Milienne-Petiot M, Higa KK, Geyer MA, Young JW. PMID: 25005251; PMCID: PMC4229584.
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PubMed Mentions:
39 Fields:
Translation:
HumansAnimals
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Inhibition of protein translation by the DISC1-Boymaw fusion gene from a Scottish family with major psychiatric disorders. Hum Mol Genet. 2014 Nov 01; 23(21):5683-705.
Ji B, Higa KK, Kim M, Zhou L, Young JW, Geyer MA, Zhou X. PMID: 24908665; PMCID: PMC4189903.
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PubMed Mentions:
22 Fields:
Translation:
HumansAnimalsCells
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Altered exploration and sensorimotor gating of the chakragati mouse model of schizophrenia. Behav Neurosci. 2014 Aug; 128(4):460-7.
Young JW, Ratty A, Dawe GS, Geyer MA. PMID: 24708299; PMCID: PMC4107138.
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PubMed Mentions:
3 Fields:
Translation:
Animals
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Isolation rearing effects on probabilistic learning and cognitive flexibility in rats. Cogn Affect Behav Neurosci. 2014 Mar; 14(1):388-406.
Amitai N, Young JW, Higa K, Sharp RF, Geyer MA, Powell SB. PMID: 23943516; PMCID: PMC3923850.
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PubMed Mentions:
39 Fields:
Translation:
Animals
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Prepulse inhibition in HIV-1 gp120 transgenic mice after withdrawal from chronic methamphetamine. Behav Pharmacol. 2014 Feb; 25(1):12-22.
Henry BL, Geyer MA, Buell MR, Perry W, Young JW, Minassian A, Translational Methamphetamine AIDS Research Center (TMARC) Group. PMID: 24281153; PMCID: PMC3926694.
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PubMed Mentions:
23 Fields:
Translation:
HumansAnimals
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Sleep deprivation impairs performance in the 5-choice continuous performance test: similarities between humans and mice. Behav Brain Res. 2014 Mar 15; 261:40-8.
van Enkhuizen J, Acheson D, Risbrough V, Drummond S, Geyer MA, Young JW. PMID: 24333377; PMCID: PMC3937379.
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PubMed Mentions:
34 Fields:
Translation:
HumansAnimals
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Dopamine depletion attenuates some behavioral abnormalities in a hyperdopaminergic mouse model of bipolar disorder. J Affect Disord. 2014 Feb; 155:247-54.
van Enkhuizen J, Geyer MA, Halberstadt AL, Zhuang X, Young JW. PMID: 24287168; PMCID: PMC3924859.
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PubMed Mentions:
25 Fields:
Translation:
Animals
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Evaluating the role of the alpha-7 nicotinic acetylcholine receptor in the pathophysiology and treatment of schizophrenia. Biochem Pharmacol. 2013 Oct 15; 86(8):1122-32.
Young JW, Geyer MA. PMID: 23856289; PMCID: PMC3797190.
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PubMed Mentions:
56 Fields:
Translation:
Humans
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Reward learning as a potential target for pharmacological augmentation of cognitive remediation for schizophrenia: a roadmap for preclinical development. Front Neurosci. 2013; 7:103.
Acheson DT, Twamley EW, Young JW. PMID: 23785309; PMCID: PMC3684768.
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PubMed Mentions:
15
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Prolonged Ketamine Effects in Sp4 Hypomorphic Mice: Mimicking Phenotypes of Schizophrenia. PLoS One. 2013; 8(6):e66327.
Ji B, Wang X, Pinto-Duarte A, Kim M, Caldwell S, Young JW, Behrens MM, Sejnowski TJ, Geyer MA, Zhou X. PMID: 23823008; PMCID: PMC3688895.
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PubMed Mentions:
15 Fields:
Translation:
AnimalsCells
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Inhibitory deficits in euthymic bipolar disorder patients assessed in the human behavioral pattern monitor. J Affect Disord. 2013 Sep 25; 150(3):948-54.
Henry BL, Minassian A, Patt VM, Hua J, Young JW, Geyer MA, Perry W. PMID: 23759280; PMCID: PMC3759601.
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PubMed Mentions:
22 Fields:
Translation:
Humans
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Further evidence for ClockΔ19 mice as a model for bipolar disorder mania using cross-species tests of exploration and sensorimotor gating. Behav Brain Res. 2013 Jul 15; 249:44-54.
van Enkhuizen J, Minassian A, Young JW. PMID: 23623885; PMCID: PMC3672322.
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PubMed Mentions:
23 Fields:
Translation:
Animals
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Bridging the bench to bedside gap: validation of a reverse-translated rodent continuous performance test using functional magnetic resonance imaging. Psychiatry Res. 2013 Jun 30; 212(3):183-91.
McKenna BS, Young JW, Dawes SE, Asgaard GL, Eyler LT. PMID: 23570915.
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PubMed Mentions:
23 Fields:
Translation:
Humans
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Demand and modality of directed attention modulate "pre-attentive" sensory processes in schizophrenia patients and nonpsychiatric controls. Schizophr Res. 2013 May; 146(1-3):326-35.
Rissling AJ, Park SH, Young JW, Rissling MB, Sugar CA, Sprock J, Mathias DJ, Pela M, Sharp RF, Braff DL, Light GA. PMID: 23490760; PMCID: PMC3622836.
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PubMed Mentions:
30 Fields:
Translation:
Humans
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Cognitive performance and response inhibition in developmentally vitamin D (DVD)-deficient rats. Behav Brain Res. 2013 Apr 01; 242:47-53.
Turner KM, Young JW, McGrath JJ, Eyles DW, Burne TH. PMID: 23275047.
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PubMed Mentions:
31 Fields:
Translation:
Animals
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Nicotinic agonist-induced improvement of vigilance in mice in the 5-choice continuous performance test. Behav Brain Res. 2013 Mar 01; 240:119-33.
Young JW, Meves JM, Geyer MA. PMID: 23201359; PMCID: PMC3538919.
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PubMed Mentions:
41 Fields:
Translation:
Animals
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Chronic valproate attenuates some, but not all, facets of mania-like behaviour in mice. Int J Neuropsychopharmacol. 2013 Jun; 16(5):1021-31.
van Enkhuizen J, Geyer MA, Kooistra K, Young JW. PMID: 23164454; PMCID: PMC3920978.
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PubMed Mentions:
32 Fields:
Translation:
Animals
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Consideration of species differences in developing novel molecules as cognition enhancers. Neurosci Biobehav Rev. 2013 Nov; 37(9 Pt B):2181-93.
Young JW, Jentsch JD, Bussey TJ, Wallace TL, Hutcheson DM. PMID: 23064177; PMCID: PMC3594426.
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PubMed Mentions:
26 Fields:
Translation:
HumansAnimals
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A novel visuospatial priming task for rats with relevance to Tourette syndrome and modulation of dopamine levels. Neurosci Biobehav Rev. 2013 Jul; 37(6):1139-49.
Amitai N, Weber M, Swerdlow NR, Sharp RF, Breier MR, Halberstadt AL, Young JW. PMID: 23010529; PMCID: PMC3556379.
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PubMed Mentions:
6 Fields:
Translation:
HumansAnimals
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Differential effects of dopamine transporter inhibitors in the rodent Iowa gambling task: relevance to mania. Psychopharmacology (Berl). 2013 Feb; 225(3):661-74.
van Enkhuizen J, Geyer MA, Young JW. PMID: 22945515; PMCID: PMC3537839.
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PubMed Mentions:
32 Fields:
Translation:
HumansAnimals
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Behavioral effects of chronic methamphetamine treatment in HIV-1 gp120 transgenic mice. Behav Brain Res. 2013 Jan 01; 236(1):210-220.
Henry BL, Geyer MA, Buell M, Perry W, Young JW, Minassian A, Translational Methamphetamine AIDS Research Center (TMARC) Group. PMID: 22960458; PMCID: PMC3482284.
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PubMed Mentions:
23 Fields:
Translation:
Animals
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The 3rd Schizophrenia International Research Society Conference, 14-18 April 2012, Florence, Italy: summaries of oral sessions. Schizophr Res. 2012 Oct; 141(1):e1-e24.
Abbs B, Achalia RM, Adelufosi AO, Aktener AY, Beveridge NJ, Bhakta SG, Blackman RK, Bora E, Byun MS, Cabanis M, Carrion R, Castellani CA, Chow TJ, Dmitrzak-Weglarz M, Gayer-Anderson C, Gomes FV, Haut K, Hori H, Kantrowitz JT, Kishimoto T, Lee FH, Lin A, Palaniyappan L, Quan M, Rubio MD, Ruiz de Azúa S, Sahoo S, Strauss GP, Szczepankiewicz A, Thompson AD, Trotta A, Tully LM, Uchida H, Velthorst E, Young JW, O'Shea A, Delisi LE. PMID: 22910407; PMCID: PMC3877922.
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PubMed Mentions:
5 Fields:
Translation:
Humans
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Four factors underlying mouse behavior in an open field. Behav Brain Res. 2012 Jul 15; 233(1):55-61.
Tanaka S, Young JW, Halberstadt AL, Masten VL, Geyer MA. PMID: 22569582; PMCID: PMC3866095.
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PubMed Mentions:
38 Fields:
Translation:
Animals
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Attentional processing in C57BL/6J mice exposed to developmental vitamin D deficiency. PLoS One. 2012; 7(4):e35896.
Harms LR, Turner KM, Eyles DW, Young JW, McGrath JJ, Burne TH. PMID: 22563415; PMCID: PMC3338544.
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PubMed Mentions:
21 Fields:
Translation:
Animals
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Measuring the construct of executive control in schizophrenia: defining and validating translational animal paradigms for discovery research. Neurosci Biobehav Rev. 2013 Nov; 37(9 Pt B):2125-40.
Gilmour G, Arguello A, Bari A, Brown VJ, Carter C, Floresco SB, Jentsch DJ, Tait DS, Young JW, Robbins TW. PMID: 22548905.
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PubMed Mentions:
36 Fields:
Translation:
HumansAnimals
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Hippocampal calbindin-1 immunoreactivity correlate of recognition memory performance in aged mice. Neurosci Lett. 2012 May 10; 516(1):161-5.
Soontornniyomkij V, Risbrough VB, Young JW, Soontornniyomkij B, Jeste DV, Achim CL. PMID: 22503902; PMCID: PMC3338865.
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PubMed Mentions:
20 Fields:
Translation:
AnimalsCells
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Examining the genetic and neural components of cognitive flexibility using mice. Physiol Behav. 2012 Dec 05; 107(5):666-9.
Brigman JL, Powell EM, Mittleman G, Young JW. PMID: 22234243; PMCID: PMC3337351.
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PubMed Mentions:
9 Fields:
Translation:
Animals
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Behavioral animal models to assess pro-cognitive treatments for schizophrenia. Handb Exp Pharmacol. 2012; (213):39-79.
Young JW, Amitai N, Geyer MA. PMID: 23027412.
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PubMed Mentions:
16 Fields:
Translation:
Animals
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Predictive animal models of mania: hits, misses and future directions. Br J Pharmacol. 2011 Oct; 164(4):1263-84.
Young JW, Henry BL, Geyer MA. PMID: 21410454; PMCID: PMC3229761.
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PubMed Mentions:
62 Fields:
Translation:
HumansAnimals
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D₁ receptor activation improves vigilance in rats as measured by the 5-choice continuous performance test. Psychopharmacology (Berl). 2012 Mar; 220(1):129-41.
Barnes SA, Young JW, Neill JC. PMID: 21901319; PMCID: PMC5870138.
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PubMed Mentions:
21 Fields:
Translation:
Animals
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Repeated assessment of exploration and novelty seeking in the human behavioral pattern monitor in bipolar disorder patients and healthy individuals. PLoS One. 2011; 6(8):e24185.
Minassian A, Henry BL, Young JW, Masten V, Geyer MA, Perry W. PMID: 21912623; PMCID: PMC3166173.
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PubMed Mentions:
32 Fields:
Translation:
Humans
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Factor analysis of attentional set-shifting performance in young and aged mice. Behav Brain Funct. 2011 Aug 12; 7:33.
Tanaka S, Young JW, Gresack JE, Geyer MA, Risbrough VB. PMID: 21838910; PMCID: PMC3174878.
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PubMed Mentions:
5 Fields:
Translation:
Animals
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Delayed procedural learning in α7-nicotinic acetylcholine receptor knockout mice. Genes Brain Behav. 2011 Oct; 10(7):720-33.
Young JW, Meves JM, Tarantino IS, Caldwell S, Geyer MA. PMID: 21679297; PMCID: PMC3918170.
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PubMed Mentions:
50 Fields:
Translation:
Animals
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Mouse pharmacological models of cognitive disruption relevant to schizophrenia. Neuropharmacology. 2012 Mar; 62(3):1381-90.
Young JW, Powell SB, Geyer MA. PMID: 21726569; PMCID: PMC3217063.
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PubMed Mentions:
20 Fields:
Translation:
HumansAnimals
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Rats tested after a washout period from sub-chronic PCP administration exhibited impaired performance in the 5-Choice Continuous Performance Test (5C-CPT) when the attentional load was increased. Neuropharmacology. 2012 Mar; 62(3):1432-41.
Barnes SA, Young JW, Neill JC. PMID: 21569782; PMCID: PMC5870141.
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PubMed Mentions:
31 Fields:
Translation:
Animals
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The effect of reduced dopamine D4 receptor expression in the 5-choice continuous performance task: Separating response inhibition from premature responding. Behav Brain Res. 2011 Sep 12; 222(1):183-92.
Young JW, Powell SB, Scott CN, Zhou X, Geyer MA. PMID: 21458500; PMCID: PMC3531561.
View in:
PubMed Mentions:
41 Fields:
Translation:
Animals
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Increased hippocampal accumulation of autophagosomes predicts short-term recognition memory impairment in aged mice. Age (Dordr). 2012 Apr; 34(2):305-16.
Soontornniyomkij V, Risbrough VB, Young JW, Soontornniyomkij B, Jeste DV, Achim CL. PMID: 21431350; PMCID: PMC3312638.
View in:
PubMed Mentions:
13 Fields:
Translation:
AnimalsCells
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Increased risk-taking behavior in dopamine transporter knockdown mice: further support for a mouse model of mania. J Psychopharmacol. 2011 Jul; 25(7):934-43.
Young JW, van Enkhuizen J, Winstanley CA, Geyer MA. PMID: 21421642; PMCID: PMC3568506.
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PubMed Mentions:
52 Fields:
Translation:
Animals
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Dopamine receptor mediation of the exploratory/hyperactivity effects of modafinil. Neuropsychopharmacology. 2011 Jun; 36(7):1385-96.
Young JW, Kooistra K, Geyer MA. PMID: 21412225; PMCID: PMC3096808.
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PubMed Mentions:
24 Fields:
Translation:
Animals
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Effect of methamphetamine dependence on inhibitory deficits in a novel human open-field paradigm. Psychopharmacology (Berl). 2011 Jun; 215(4):697-707.
Henry BL, Minassian A, van Rhenen M, Young JW, Geyer MA, Perry W, Translational Methamphetamine AIDS Research Center (TMARC) Group. PMID: 21279333; PMCID: PMC3102201.
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PubMed Mentions:
18 Fields:
Translation:
Humans
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Working memory span capacity improved by a D2 but not D1 receptor family agonist. Behav Brain Res. 2011 Jun 01; 219(2):181-8.
Tarantino IS, Sharp RF, Geyer MA, Meves JM, Young JW. PMID: 21232557; PMCID: PMC3073724.
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13 Fields:
Translation:
Animals
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Initial evidence linking synaptic superoxide production with poor short-term memory in aged mice. Brain Res. 2011 Jan 12; 1368:65-70.
Ali SS, Young JW, Wallace CK, Gresack J, Jeste DV, Geyer MA, Dugan LL, Risbrough VB. PMID: 21075081; PMCID: PMC3018762.
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PubMed Mentions:
19 Fields:
Translation:
AnimalsCells
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Evaluation of the clinical efficacy of asenapine in schizophrenia. Expert Opin Pharmacother. 2010 Aug; 11(12):2107-15.
Minassian A, Young JW. PMID: 20642375; PMCID: PMC2924192.
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PubMed Mentions:
9 Fields:
Translation:
Humans
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Quantifying over-activity in bipolar and schizophrenia patients in a human open field paradigm. Psychiatry Res. 2010 Jun 30; 178(1):84-91.
Perry W, Minassian A, Henry B, Kincaid M, Young JW, Geyer MA. PMID: 20471103; PMCID: PMC2914139.
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PubMed Mentions:
42 Fields:
Translation:
Humans
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The mouse attentional-set-shifting task: a method for assaying successful cognitive aging? Cogn Affect Behav Neurosci. 2010 May; 10(2):243-51.
Young JW, Powell SB, Geyer MA, Jeste DV, Risbrough VB. PMID: 20498348; PMCID: PMC2877277.
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PubMed Mentions:
40 Fields:
Translation:
Animals
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Short-term recognition memory impairment is associated with decreased expression of FK506 binding protein 51 in the aged mouse brain. Age (Dordr). 2010 Sep; 32(3):309-22.
Soontornniyomkij V, Risbrough VB, Young JW, Wallace CK, Soontornniyomkij B, Jeste DV, Achim CL. PMID: 20422297; PMCID: PMC2926850.
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23 Fields:
Translation:
AnimalsCells
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Cross-species assessments of motor and exploratory behavior related to bipolar disorder. Neurosci Biobehav Rev. 2010 Jul; 34(8):1296-306.
Henry BL, Minassian A, Young JW, Paulus MP, Geyer MA, Perry W. PMID: 20398694; PMCID: PMC2900445.
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PubMed Mentions:
29 Fields:
Translation:
HumansAnimals
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The mania-like exploratory profile in genetic dopamine transporter mouse models is diminished in a familiar environment and reinstated by subthreshold psychostimulant administration. Pharmacol Biochem Behav. 2010 Jul; 96(1):7-15.
Young JW, Goey AK, Minassian A, Perry W, Paulus MP, Geyer MA. PMID: 20363246; PMCID: PMC2878916.
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PubMed Mentions:
39 Fields:
Translation:
Animals
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Action of modafinil--increased motivation via the dopamine transporter inhibition and D1 receptors? Biol Psychiatry. 2010 Apr 15; 67(8):784-7.
Young JW, Geyer MA. PMID: 20132929; PMCID: PMC2849918.
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PubMed Mentions:
42 Fields:
Translation:
Animals
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Age-associated improvements in cross-modal prepulse inhibition in mice. Behav Neurosci. 2010 Feb; 124(1):133-140.
Young JW, Wallace CK, Geyer MA, Risbrough VB. PMID: 20141288; PMCID: PMC3088993.
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15 Fields:
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Animals
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PubMed Mentions:
55 Fields:
Translation:
Humans
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Animal models of schizophrenia. Curr Top Behav Neurosci. 2010; 4:391-433.
Young JW, Zhou X, Geyer MA. PMID: 21312408.
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PubMed Mentions:
35 Fields:
Translation:
HumansAnimals
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GBR 12909 administration as a mouse model of bipolar disorder mania: mimicking quantitative assessment of manic behavior. Psychopharmacology (Berl). 2010 Feb; 208(3):443-54.
Young JW, Goey AK, Minassian A, Perry W, Paulus MP, Geyer MA. PMID: 20020109; PMCID: PMC2806531.
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PubMed Mentions:
44 Fields:
Translation:
Animals
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A reverse-translational study of dysfunctional exploration in psychiatric disorders: from mice to men. Arch Gen Psychiatry. 2009 Oct; 66(10):1072-80.
Perry W, Minassian A, Paulus MP, Young JW, Kincaid MJ, Ferguson EJ, Henry BL, Zhuang X, Masten VL, Sharp RF, Geyer MA. PMID: 19805697; PMCID: PMC2897252.
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PubMed Mentions:
105 Fields:
Translation:
HumansAnimals
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Asenapine effects in animal models of psychosis and cognitive function. Psychopharmacology (Berl). 2009 Nov; 206(4):699-714.
Marston HM, Young JW, Martin FD, Serpa KA, Moore CL, Wong EH, Gold L, Meltzer LT, Azar MR, Geyer MA, Shahid M. PMID: 19462162; PMCID: PMC2755103.
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PubMed Mentions:
19 Fields:
Translation:
Animals
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Using the MATRICS to guide development of a preclinical cognitive test battery for research in schizophrenia. Pharmacol Ther. 2009 May; 122(2):150-202.
Young JW, Powell SB, Risbrough V, Marston HM, Geyer MA. PMID: 19269307; PMCID: PMC2688712.
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PubMed Mentions:
141 Fields:
Translation:
HumansAnimals
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Dopamine D1 and D2 receptor family contributions to modafinil-induced wakefulness. J Neurosci. 2009 Mar 04; 29(9):2663-5.
Young JW. PMID: 19261860; PMCID: PMC2697968.
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PubMed Mentions:
5 Fields:
Translation:
HumansAnimals
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The 5-choice continuous performance test: evidence for a translational test of vigilance for mice. PLoS One. 2009; 4(1):e4227.
Young JW, Light GA, Marston HM, Sharp R, Geyer MA. PMID: 19156216; PMCID: PMC2626630.
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PubMed Mentions:
90 Fields:
Translation:
Animals
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Atypical antipsychotics clozapine and quetiapine attenuate prepulse inhibition deficits in dopamine transporter knockout mice. Behav Pharmacol. 2008 Sep; 19(5-6):562-5.
Powell SB, Young JW, Ong JC, Caron MG, Geyer MA. PMID: 18690110; PMCID: PMC2693185.
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PubMed Mentions:
29 Fields:
Translation:
Animals
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Progressive impairment in olfactory working memory in a mouse model of Mild Cognitive Impairment. Neurobiol Aging. 2009 Sep; 30(9):1430-43.
Young JW, Sharkey J, Finlayson K. PMID: 18242780.
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PubMed Mentions:
32 Fields:
Translation:
HumansAnimals
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A reverse-translational approach to bipolar disorder: rodent and human studies in the Behavioral Pattern Monitor. Neurosci Biobehav Rev. 2007; 31(6):882-96.
Young JW, Minassian A, Paulus MP, Geyer MA, Perry W. PMID: 17706782; PMCID: PMC2025688.
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PubMed Mentions:
58 Fields:
Translation:
HumansAnimals
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The odour span task: a novel paradigm for assessing working memory in mice. Neuropharmacology. 2007 Feb; 52(2):634-45.
Young JW, Kerr LE, Kelly JS, Marston HM, Spratt C, Finlayson K, Sharkey J. PMID: 17097694.
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PubMed Mentions:
34 Fields:
Translation:
HumansAnimals
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Impaired attention is central to the cognitive deficits observed in alpha 7 deficient mice. Eur Neuropsychopharmacol. 2007 Jan 15; 17(2):145-55.
Young JW, Crawford N, Kelly JS, Kerr LE, Marston HM, Spratt C, Finlayson K, Sharkey J. PMID: 16650968.
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PubMed Mentions:
101 Fields:
Translation:
AnimalsCells
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Nicotine improves sustained attention in mice: evidence for involvement of the alpha7 nicotinic acetylcholine receptor. Neuropsychopharmacology. 2004 May; 29(5):891-900.
Young JW, Finlayson K, Spratt C, Marston HM, Crawford N, Kelly JS, Sharkey J. PMID: 14970827.
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PubMed Mentions:
88 Fields:
Translation:
AnimalsCells