Susan Little

Title(s)Professor In Residence, Medicine
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Risks, Benefits, and Stakeholder Perspectives of Molecular Epidemiology for HIV Prevention (HIV-ME)
    NIH R01MH124590Jul 8, 2020 - Apr 30, 2025
    Role: Principal Investigator
    Characterizing Privacy Perceptions and Risks in HIV Molecular Epidemiology
    NIH R21AI108351Jun 1, 2014 - May 31, 2017
    Role: Principal Investigator
    Efficacy of ART to Interrupt HIV Transmission Networks
    NIH R01MH100974May 12, 2014 - Feb 29, 2020
    Role: Principal Investigator
    Primary Infection Resource Consortium (PIRC)
    NIH R24AI106039Aug 20, 2013 - Mar 31, 2022
    Role: Principal Investigator
    Determinants of HIV Transmission
    NIH P01AI074621Mar 15, 2008 - Feb 28, 2015
    Role: Principal Investigator
    General Clinical Research Center
    NIH M01RR000827Mar 1, 1974 - Nov 30, 2010
    Role: Co-Investigator

    Collapse ORNG Applications 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Ethical and practical considerations for HIV cure-related research at the end-of-life: a qualitative interview and focus group study in the United States. BMC Med Ethics. 2022 Jan 11; 23(1):2. Kanazawa J, Gianella S, Concha-Garcia S, Taylor J, Kaytes A, Christensen C, Patel H, Ndukwe S, Rawlings SA, Hendrickx S, Little S, Brown B, Smith D, Dubé K. PMID: 35012544; PMCID: PMC8748179.
      View in: PubMed   Mentions:
    2. COVID-19 vaccination is protective of clinical disease in solid organ transplant recipients. Transpl Infect Dis. 2022 Jan 05. Aslam S, Liu J, Sigler R, Syed RR, Tu XM, Little SJ, De Gruttola V. PMID: 34989104.
      View in: PubMed   Mentions:
    3. 4th Generation HIV screening in the emergency department: net profit or loss for hospitals? AIDS Care. 2021 Nov 27; 1-5. Hoenigl M, Lo M, Coyne CJ, Wagner GA, Blumenthal J, Mathur K, Horton LE, Martin TCS, Vilke GM, Little SJ. PMID: 34839750.
      View in: PubMed   Mentions:
    4. Frequency of post treatment control varies by antiretroviral therapy restart and viral load criteria. AIDS. 2021 Nov 01; 35(13):2225-2227. Fajnzylber J, Sharaf R, Hutchinson JN, Aga E, Bosch RJ, Hartogensis W, Jacobson JM, Connick E, Volberding P, Skiest DJ, Margolis D, Sneller MC, Little SJ, Gulick RM, Mellors JW, Gandhi RT, Schooley RT, Henry K, Tebas P, Deeks S, Chun TW, Collier AC, Hecht FM, Li JZ, CHAMP study team. PMID: 34127579; PMCID: PMC8490281.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    5. Dynamics and Dispersal of Local Human Immunodeficiency Virus Epidemics Within San Diego and Across the San Diego-Tijuana Border. Clin Infect Dis. 2021 Oct 05; 73(7):e2018-e2025. Vrancken B, Mehta SR, Ávila-Ríos S, García-Morales C, Tapia-Trejo D, Reyes-Terán G, Navarro-Álvarez S, Little SJ, Hoenigl M, Pines HA, Patterson T, Strathdee SA, Smith DM, Dellicour S, Chaillon A. PMID: 33079188; PMCID: PMC8492140.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCellsPHPublic Health
    6. The Performance of Pooled 3 Anatomic Site Testing for Chlamydia trachomatis and Neisseria gonorrhoeae Among Men Who Have Sex With Men and Transgender Women. Sex Transm Dis. 2021 Oct 01; 48(10):733-737. Bristow CC, Mehta SR, Hoenigl M, Little SJ. PMID: 34110736; PMCID: PMC8435040.
      View in: PubMed   Mentions:    Fields:    
    7. Evaluation of HIV-1 reservoir size and broadly neutralizing antibodies (bNAb) susceptibility in acute ART treated individuals. AIDS. 2021 Sep 29. Moldt B, Günthard HF, Workowski KA, Little SJ, Eron JJ, Overton ET, Lehmann C, Rokx C, Kozal MJ, Gandhi RT, Braun DL, Parvangada A, Li J, Martin R, Selzer L, Cox S, Margot N, Liu H, Slamowitz D, Makadzange T, Collins SE, Geleziunas R, Callebaut C. PMID: 34586088.
      View in: PubMed   Mentions:    Fields:    
    8. Phase 3 Safety and Efficacy of AZD1222 (ChAdOx1 nCoV-19) Covid-19 Vaccine. N Engl J Med. 2021 Sep 29. Falsey AR, Sobieszczyk ME, Hirsch I, Sproule S, Robb ML, Corey L, Neuzil KM, Hahn W, Hunt J, Mulligan MJ, McEvoy C, DeJesus E, Hassman M, Little SJ, Pahud BA, Durbin A, Pickrell P, Daar ES, Bush L, Solis J, Carr QO, Oyedele T, Buchbinder S, Cowden J, Vargas SL, Benavides AG, Call R, Keefer MC, Kirkpatrick BD, Pullman J, Tong T, Isaacs MB, Benkeser D, Janes HE, Nason MC, Green JA, Kelly EJ, Maaske J, Mueller N, Shoemaker K, Takas T, Marshall RP, Pangalos MN, Villafana T, Gonzalez-Lopez A, AstraZeneca AZD1222 Clinical Study Group. PMID: 34587382; PMCID: PMC8522798.
      View in: PubMed   Mentions:    Fields:    
    9. Incorporating metadata in HIV transmission network reconstruction: A machine learning feasibility assessment. PLoS Comput Biol. 2021 Sep; 17(9):e1009336. Mazrouee S, Little SJ, Wertheim JO. PMID: 34550966; PMCID: PMC8457453.
      View in: PubMed   Mentions:    Fields:    
    10. Effective Human Immunodeficiency Virus Molecular Surveillance Requires Identification of Incident Cases of Infection. Clin Infect Dis. 2021 09 07; 73(5):842-849. Little SJ, Chen T, Wang R, Anderson C, Pond SK, Nakazawa M, Mathews WC, DeGruttola V, Smith DM. PMID: 34492694; PMCID: PMC8423467.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCellsPHPublic Health
    11. Interest, Concerns, and Attitudes Among Men Who Have Sex With Men and Health Care Providers Toward Prophylactic Use of Doxycycline Against Chlamydia trachomatis Infections and Syphilis. Sex Transm Dis. 2021 Sep 01; 48(9):615-619. Park JJ, Stafylis C, Pearce DD, Taylor J, Little SJ, Kojima N, Gorin AM, Klausner JD. PMID: 33560092.
      View in: PubMed   Mentions: 2     Fields:    
    12. Correction to: A Cross‑Sectional Study to Evaluate the Effects of Age and Duration of HIV Infection on Anxiety and Depression in Cisgender Men. AIDS Behav. 2021 Aug 24. Gianella S, Saloner R, Curtin G, Little SJ, Heaton A, Montoya JL, Letendre SL, Marquine MJ, Jeste DV, Moore DJ. PMID: 34427814.
      View in: PubMed   Mentions:    Fields:    
    13. Clinical effectiveness of COVID-19 vaccination in solid organ transplant recipients. Transpl Infect Dis. 2021 Jul 29; e13705. Aslam S, Adler E, Mekeel K, Little SJ. PMID: 34324256; PMCID: PMC8420394.
      View in: PubMed   Mentions: 2     Fields:    
    14. A Cross-Sectional Study to Evaluate the Effects of Age and Duration of HIV Infection on Anxiety and Depression in Cisgender Men. AIDS Behav. 2021 Jul 21. Gianella S, Saloner R, Curtin G, Little SJ, Heaton A, Montoya JL, Letendre SL, Marquine MJ, Jeste DV, Moore DJ. PMID: 34287757; PMCID: PMC8294268.
      View in: PubMed   Mentions:    Fields:    
    15. Ethical and practical considerations for interventional HIV cure-related research at the end-of-life: A qualitative study with key stakeholders in the United States. PLoS One. 2021; 16(7):e0254148. Kanazawa J, Gianella S, Concha-Garcia S, Taylor J, Kaytes A, Christensen C, Patel H, Ndukwe S, Rawlings S, Hendrickx S, Little S, Brown B, Smith D, Dubé K. PMID: 34270612; PMCID: PMC8284787.
      View in: PubMed   Mentions:    Fields:    
    16. MrHAMER yields highly accurate single molecule viral sequences enabling analysis of intra-host evolution. Nucleic Acids Res. 2021 07 09; 49(12):e70. Gallardo CM, Wang S, Montiel-Garcia DJ, Little SJ, Smith DM, Routh AL, Torbett BE. PMID: 33849057; PMCID: PMC8266615.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    17. Rapid Antiretroviral Therapy Among Individuals With Acute and Early HIV. Clin Infect Dis. 2021 07 01; 73(1):130-133. Martin TCS, Abrams M, Anderson C, Little SJ. PMID: 32777035; PMCID: PMC8246801.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    18. Phylogenetic Cluster Analysis: Persons With Undiagnosed Infection Drive Human Immunodeficiency Virus Transmission in a Population With High Levels of Virologic Suppression. Clin Infect Dis. 2021 06 15; 72(12):2184-2186. Mehta SR, Little SJ. PMID: 32266376; PMCID: PMC8204770.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    19. Attitudes and perceptions of next-of-kin/loved ones toward end-of-life HIV cure-related research: A qualitative focus group study in Southern California. PLoS One. 2021; 16(5):e0250882. Javadi SS, Mathur K, Concha-Garcia S, Patel H, Perry KE, Lo M, Taylor J, Kaytes A, Little S, Gianella S, Smith D, Dubé K. PMID: 33961653; PMCID: PMC8104928.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    20. Biometric Registration to an HIV Research Study may Deter Participation. AIDS Behav. 2021 May; 25(5):1552-1559. Abrams MP, Torres FE, Little SJ. PMID: 32767155; PMCID: PMC7867657.
      View in: PubMed   Mentions:    Fields:    Translation:HumansPHPublic Health
    21. Effective HIV Molecular Surveillance Requires Identification of Incident Cases of Infection. Clin Infect Dis. 2021 Feb 15. Little SJ, Chen T, Wang R, Anderson C, Kosakovsky Pond S, Nakazawa M, Mathews WC, DeGruttola V, Smith DM. PMID: 33588434.
      View in: PubMed   Mentions:    Fields:    
    22. HIV screening in emergency departments: Linkage works but what about retention? Acad Emerg Med. 2021 08; 28(8):913-917. Mathur K, Blumenthal J, Horton LE, Wagner GA, Martin TCS, Lo M, Gianella S, Vilke GM, Coyne CJ, Little SJ, Hoenigl M. PMID: 33314418; PMCID: PMC8196073.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansPHPublic Health
    23. Integrase Strand Transfer Inhibitors Play the Main Role in Greater Weight Gain Among Men With Acute and Early HIV Infection. Open Forum Infect Dis. 2021 Jan; 8(1):ofaa619. Wu KS, Anderson C, Little SJ. PMID: 33511237; PMCID: PMC7813183.
      View in: PubMed   Mentions: 1  
    24. "[It] is now my responsibility to fulfill that wish:" Clinical and rapid autopsy staff members' experiences and perceptions of HIV reservoir research at the end of life. PLoS One. 2020; 15(11):e0242420. Perry KE, Taylor J, Patel H, Javadi SS, Mathur K, Kaytes A, Concha-Garcia S, Little S, Smith D, Gianella S, Dubé K. PMID: 33206710; PMCID: PMC7673534.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    25. Addressing Ethical Challenges in US-Based HIV Phylogenetic Research. J Infect Dis. 2020 11 13; 222(12):1997-2006. Dawson L, Benbow N, Fletcher FE, Kassaye S, Killelea A, Latham SR, Lee LM, Leitner T, Little SJ, Mehta SR, Martinez O, Minalga B, Poon A, Rennie S, Sugarman J, Sweeney P, Torian LV, Wertheim JO. PMID: 32525980; PMCID: PMC7661760.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCellsPHPublic Health
    26. Grindr Users Take More Risks, but Are More Open to Human Immunodeficiency Virus (HIV) Pre-exposure Prophylaxis: Could This Dating App Provide a Platform for HIV Prevention Outreach? Clin Infect Dis. 2020 10 23; 71(7):e135-e140. Hoenigl M, Little SJ, Grelotti D, Skaathun B, Wagner GA, Weibel N, Stockman JK, Smith DM. PMID: 31677383; PMCID: PMC7583417.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCellsPHPublic Health
    27. Bayesian reconstruction of transmission trees from genetic sequences and uncertain infection times. Stat Appl Genet Mol Biol. 2020 Oct 21. Montazeri H, Little S, Mozaffarilegha M, Beerenwinkel N, DeGruttola V. PMID: 33085643; PMCID: PMC8212962.
      View in: PubMed   Mentions:    Fields:    
    28. Switching to Tenofovir Alafenamide in Elvitegravir-Based Regimens: Pharmacokinetics and Antiviral Activity in Cerebrospinal Fluid. Clin Infect Dis. 2020 08 14; 71(4):982-988. Ma Q, Ocque AJ, Morse GD, Sanders C, Burgi A, Little SJ, Letendre SL. PMID: 31560741; PMCID: PMC7428394.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    29. Perceptions of Next-of-Kin/Loved Ones About Last Gift Rapid Research Autopsy Study Enrolling People with HIV/AIDS at the End of Life: A Qualitative Interview Study. AIDS Res Hum Retroviruses. 2020 12; 36(12):1033-1046. Dubé K, Patel H, Concha-Garcia S, Perry KE, Mathur K, Javadi SS, Taylor J, Kaytes A, Brown B, Sauceda JA, Little S, Hendrickx S, Rawlings SA, Smith DM, Gianella S. PMID: 32449624; PMCID: PMC7703245.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    30. "My Death Will Not [Be] in Vain": Testimonials from Last Gift Rapid Research Autopsy Study Participants Living with HIV at the End of Life. AIDS Res Hum Retroviruses. 2020 12; 36(12):1071-1082. Perry KE, Dubé K, Concha-Garcia S, Patel H, Kaytes A, Taylor J, Javadi SS, Mathur K, Lo M, Brown B, Sauceda JA, Wohl DA, Little S, Hendrickx S, Rawlings SA, Smith DM, Gianella S. PMID: 32449625; PMCID: PMC7703253.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    31. Salvage Antiretroviral Therapy: Time for "DeNUKElearization"? J Infect Dis. 2020 04 07; 221(9):1390-1393. Hoenigl M, Little SJ. PMID: 31136663; PMCID: PMC7137884.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    32. Genetic Network Analysis to Assess the Risk of Human Immunodeficiency Virus Transmission Among Men Who Have Sex With Men Seeking Partners on the Internet. Clin Infect Dis. 2020 02 14; 70(5):925-932. Martin TCS, Chaillon A, Graves SK, Lin T, Gianella S, Smith DM, Little SJ, Hoenigl M. PMID: 30953067; PMCID: PMC7319271.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    33. Optimizing Screening for HIV. Open Forum Infect Dis. 2020 Feb; 7(2):ofaa024. Chaillon A, Hoenigl M, Freitas L, Feldman H, Tilghman W, Wang L, Smith D, Little S, Mehta SR. PMID: 32055638; PMCID: PMC7009491.
      View in: PubMed   Mentions: 1  
    34. Canine Leishmaniasis Control in the Context of One Health. Emerg Infect Dis. 2019 12; 25(12):1-4. Dantas-Torres F, Miró G, Baneth G, Bourdeau P, Breitschwerdt E, Capelli G, Cardoso L, Day MJ, Dobler G, Ferrer L, Irwin P, Jongejan F, Kempf VAJ, Kohn B, Lappin M, Little S, Madder M, Maggi R, Maia C, Marcondes M, Naucke T, Oliva G, Pennisi MG, Penzhorn BL, Peregrine A, Pfeffer M, Roura X, Sainz A, Shin S, Solano-Gallego L, Straubinger RK, Tasker S, Traub R, Wright I, Bowman DD, Gradoni L, Otranto D. PMID: 31742505; PMCID: PMC6874277.
      View in: PubMed   Mentions: 14     Fields:    Translation:Animals
    35. I wanted it as soon as possible: a qualitative exploration of reactions to access to same-day ART start among participants in San Diego's ART-NET project. AIDS Care. 2020 09; 32(9):1191-1197. Amico KR, Miller J, Schairer C, Gianella S, Little SJ, Hoenigl M. PMID: 31713432; PMCID: PMC7214217.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    36. Universal HIV and Birth Cohort HCV Screening in San Diego Emergency Departments. Sci Rep. 2019 10 09; 9(1):14479. Hoenigl M, Mathur K, Blumenthal J, Brennan J, Zuazo M, McCauley M, Horton LE, Wagner GA, Reed SL, Vilke GM, Coyne CJ, Little SJ. PMID: 31597939; PMCID: PMC6785532.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansPHPublic Health
    37. Meta-analysis of the Cepheid Xpert® CT/NG assay for extragenital detection of Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) infections. Sex Health. 2019 08; 16(4):314-319. Bristow CC, Morris SR, Little SJ, Mehta SR, Klausner JD. PMID: 31296280; PMCID: PMC6954977.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    38. Trust and Expectations of Researchers and Public Health Departments for the Use of HIV Molecular Epidemiology. AJOB Empir Bioeth. 2019 Jul-Sep; 10(3):201-213. Schairer CE, Mehta SR, Vinterbo SA, Hoenigl M, Kalichman M, Little SJ. PMID: 31050604; PMCID: PMC7233550.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    39. Ethical issues in HIV phylogenetics and molecular epidemiology. Curr Opin HIV AIDS. 2019 05; 14(3):221-226. Mehta SR, Schairer C, Little S. PMID: 30946143; PMCID: PMC6450547.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCellsPHPublic Health
    40. Primary Incidence of Hepatitis C Virus Infection Among HIV-Infected Men Who Have Sex With Men in San Diego, 2000-2015. Open Forum Infect Dis. 2019 Apr; 6(4):ofz160. Chaillon A, Sun X, Cachay ER, Looney D, Wyles D, Garfein RS, Martin TCS, Martin TCS, Jain S, Mehta SR, Smith DM, Little SJ, Martin NK. PMID: 31041355; PMCID: PMC6483132.
      View in: PubMed   Mentions: 7  
    41. Herd Immunity Likely Protected the Men Who Have Sex With Men in the Recent Hepatitis A Outbreak in San Diego, California. Clin Infect Dis. 2019 03 19; 68(7):1228-1230. Smith D, Huynh C, Moore AJ, Frick A, Anderson C, Porrachia M, Scott B, Stous S, Schooley R, Little S, Santos AT. PMID: 30052941; PMCID: PMC7182127.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCellsPHPublic Health
    42. Attitudes and Preferences Regarding the Use of Rapid Self-Testing for Sexually Transmitted Infections and HIV in San Diego Area Men Who Have Sex With Men. Open Forum Infect Dis. 2019 Mar; 6(3):ofz043. Cushman TA, Graves SK, Little SJ. PMID: 30906798; PMCID: PMC6424479.
      View in: PubMed   Mentions: 2  
    43. The inhibitor apoptosis protein antagonist Debio 1143 Is an attractive HIV-1 latency reversal candidate. PLoS One. 2019; 14(2):e0211746. Bobardt M, Kuo J, Chatterji U, Chanda S, Little SJ, Wiedemann N, Vuagniaux G, Gallay PA. PMID: 30716099; PMCID: PMC6361451.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    44. The Control of HIV After Antiretroviral Medication Pause (CHAMP) Study: Posttreatment Controllers Identified From 14 Clinical Studies. J Infect Dis. 2018 11 05; 218(12):1954-1963. Namazi G, Fajnzylber JM, Aga E, Bosch RJ, Acosta EP, Sharaf R, Hartogensis W, Jacobson JM, Connick E, Volberding P, Skiest D, Margolis D, Sneller MC, Little SJ, Gianella S, Smith DM, Kuritzkes DR, Gulick RM, Mellors JW, Mehraj V, Gandhi RT, Mitsuyasu R, Schooley RT, Henry K, Tebas P, Deeks SG, Chun TW, Collier AC, Routy JP, Hecht FM, Walker BD, Li JZ. PMID: 30085241; PMCID: PMC6217727.
      View in: PubMed   Mentions: 51     Fields:    Translation:HumansCells
    45. Ethical considerations for HIV cure-related research at the end of life. BMC Med Ethics. 2018 10 20; 19(1):83. Dubé K, Gianella S, Concha-Garcia S, Little SJ, Kaytes A, Taylor J, Mathur K, Javadi S, Nathan A, Patel H, Luter S, Philpott-Jones S, Brown B, Smith D. PMID: 30342507; PMCID: PMC6196016.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    46. Antigen-specific antibody Fc glycosylation enhances humoral immunity via the recruitment of complement. Sci Immunol. 2018 08 17; 3(26). Lofano G, Gorman MJ, Yousif AS, Yu WH, Fox JM, Dugast AS, Ackerman ME, Suscovich TJ, Weiner J, Barouch D, Streeck H, Little S, Smith D, Richman D, Lauffenburger D, Walker BD, Diamond MS, Alter G. PMID: 30120121; PMCID: PMC6298214.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    47. A Simple Symptom Score for Acute Human Immunodeficiency Virus Infection in a San Diego Community-Based Screening Program. Clin Infect Dis. 2018 06 18; 67(1):105-111. Lin TC, Gianella S, Tenenbaum T, Little SJ, Hoenigl M. PMID: 29293891; PMCID: PMC6005041.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCellsPHPublic Health
    48. Temporal variation in HIV-specific IgG subclass antibodies during acute infection differentiates spontaneous controllers from chronic progressors. AIDS. 2018 02 20; 32(4):443-450. Sadanand S, Das J, Chung AW, Schoen MK, Lane S, Suscovich TJ, Streeck H, Smith DM, Little SJ, Lauffenburger DA, Richman DD, Alter G. PMID: 29239894; PMCID: PMC5983383.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    49. Size, Composition, and Evolution of HIV DNA Populations during Early Antiretroviral Therapy and Intensification with Maraviroc. J Virol. 2018 02 01; 92(3). Chaillon A, Gianella S, Lada SM, Perez-Santiago J, Jordan P, Ignacio C, Karris M, Richman DD, Mehta SR, Little SJ, Wertheim JO, Smith DM. PMID: 29142136; PMCID: PMC5774877.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    50. Infection Staging and Incidence Surveillance Applications of High Dynamic Range Diagnostic Immuno-Assay Platforms. . 2017 12 15; 76(5):547-555. Grebe E, Welte A, Hall J, Keating SM, Facente SN, Marson K, Martin JN, Little SJ, Price MA, Kallas EG, Busch MP, Pilcher CD, Murphy G. PMID: 28914669; PMCID: PMC5680100.
      View in: PubMed   Mentions: 6  Translation:HumansCellsPHPublic Health
    51. Perceptions of molecular epidemiology studies of HIV among stakeholders. J Public Health Res. 2017 Dec 13; 6(3):992. Schairer C, Mehta SR, Vinterbo SA, Hoenigl M, Kalichman M, Little S. PMID: 29291190; PMCID: PMC5736996.
      View in: PubMed   Mentions: 6  
    52. No Substantial Evidence for Sexual Transmission of Minority HIV Drug Resistance Mutations in Men Who Have Sex with Men. J Virol. 2017 11 01; 91(21). Chaillon A, Nakazawa M, Wertheim JO, Little SJ, Smith DM, Mehta SR, Gianella S. PMID: 28794047; PMCID: PMC5640831.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    53. Sexual Partner Concurrency Among Partners Reported by MSM with Recent HIV Infection. AIDS Behav. 2017 Oct; 21(10):3026-3034. Pines HA, Karris MY, Little SJ. PMID: 28702851; PMCID: PMC5983362.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    54. Intrasubtype B HIV-1 Superinfection Correlates with Delayed Neutralizing Antibody Response. J Virol. 2017 09 01; 91(17). Wagner GA, Landais E, Caballero G, Phung P, Kosakovsky Pond SL, Poignard P, Richman DD, Little SJ, Smith DM. PMID: 28615205; PMCID: PMC5553187.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    55. Identification and characterization of Nanobodies targeting the EphA4 receptor. J Biol Chem. 2017 07 07; 292(27):11452-11465. Schoonaert L, Rué L, Roucourt B, Timmers M, Little S, Chávez-Gutiérrez L, Dewilde M, Joyce P, Curnock A, Weber P, Haustraete J, Hassanzadeh-Ghassabeh G, De Strooper B, Van Den Bosch L, Van Damme P, Lemmens R, Robberecht W. PMID: 28526745; PMCID: PMC5500810.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    56. Increased HIV-1 superinfection risk in carriers of specific human leukocyte antigen alleles. AIDS. 2017 05 15; 31(8):1149-1158. Vesa J, Chaillon A, Wagner GA, Anderson CM, Richman DD, Smith DM, Little SJ. PMID: 28244954; PMCID: PMC5559224.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    57. Brief Report: Changes in Levels of Inflammation After Antiretroviral Treatment During Early HIV Infection in AIDS Clinical Trials Group Study A5217. . 2017 05 01; 75(1):137-141. Macatangay BJ, Yang M, Sun X, Morton J, De Gruttola V, Little S, Hogan C, Rinaldo CR, A5217 Team. PMID: 28198712; PMCID: PMC5393630.
      View in: PubMed   Mentions: 5  Translation:HumansCells
    58. Assessing the Performance of 3 Human Immunodeficiency Virus Incidence Risk Scores in a Cohort of Black and White Men Who Have Sex With Men in the South. Sex Transm Dis. 2017 05; 44(5):297-302. Jones J, Hoenigl M, Siegler AJ, Sullivan PS, Little S, Rosenberg E. PMID: 28407646; PMCID: PMC5407317.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansPHPublic Health
    59. Evaluation of the Predictive Potential of the Short Acute Retroviral Syndrome Severity Score for HIV-1 Disease Progression in Individuals With Acute HIV Infection. . 2017 04 01; 74(4):e114-e117. Hoenigl M, Braun DL, Kouyos R, Günthard HF, Little SJ. PMID: 28225720; PMCID: PMC5324781.
      View in: PubMed   Mentions: 2  Translation:Humans
    60. Longitudinal Viral Dynamics in Semen During Early HIV Infection. Clin Infect Dis. 2017 02 15; 64(4):428-434. Morris SR, Zhao M, Smith DM, Vargas MV, Little SJ, Gianella S. PMID: 28174909; PMCID: PMC5849030.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    61. Risk profile and HIV testing outcomes of women undergoing community-based testing in San Diego 2008-2014. Sci Rep. 2017 02 06; 7:42183. Graves SK, Little SJ, Hoenigl M. PMID: 28165056; PMCID: PMC5292713.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansPHPublic Health
    62. Evaluation of opt-out inpatient HIV screening at an urban teaching hospital. AIDS Care. 2017 08; 29(8):1014-1018. Osorio G, Hoenigl M, Quartarolo J, Barger K, Morris SR, Reed SL, Lee J, Little SJ. PMID: 28114789; PMCID: PMC5469710.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansPHPublic Health
    63. Partner services in adults with acute and early HIV infection. AIDS. 2017 01 14; 31(2):287-293. Green N, Hoenigl M, Chaillon A, Anderson CM, Kosakovsky Pond SL, Smith DM, Little SJ. PMID: 27831950; PMCID: PMC5177524.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansPHPublic Health
    64. Early Antiretroviral Therapy Is Associated with Lower HIV DNA Molecular Diversity and Lower Inflammation in Cerebrospinal Fluid but Does Not Prevent the Establishment of Compartmentalized HIV DNA Populations. PLoS Pathog. 2017 01; 13(1):e1006112. Oliveira MF, Chaillon A, Nakazawa M, Vargas M, Letendre SL, Strain MC, Ellis RJ, Morris S, Little SJ, Smith DM, Gianella S. PMID: 28046096; PMCID: PMC5266327.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCellsPHPublic Health
    65. Can research at the end of life be a useful tool to advance HIV cure? AIDS. 2017 01 02; 31(1):1-4. Gianella S, Taylor J, Brown TR, Kaytes A, Achim CL, Moore DJ, Little SJ, Ellis RJ, Smith DM. PMID: 27755112; PMCID: PMC5137789.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    66. Performance of the Bio-Rad Geenius HIV1/2 Supplemental Assay in Detecting "Recent" HIV Infection and Calculating Population Incidence. . 2016 Dec 15; 73(5):581-588. Keating SM, Kassanjee R, Lebedeva M, Facente SN, MacArthur JC, Grebe E, Murphy G, Welte A, Martin JN, Little S, Price MA, Kallas EG, Busch MP, Pilcher CD. PMID: 27509247; PMCID: PMC5110377.
      View in: PubMed   Mentions: 11  Translation:Cells
    67. Treatment of Acute HIV Infection and the Potential Role of Acutely HIV-Infected Persons in Cure Studies. Top Antivir Med. 2016 Dec-2017 Jan; 23(5):156-60. Little SJ. PMID: 27398768; PMCID: PMC6148942.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    68. Concurrency and HIV transmission network characteristics among MSM with recent HIV infection. AIDS. 2016 11 28; 30(18):2875-2883. Pines HA, Wertheim JO, Liu L, Garfein RS, Little SJ, Karris MY. PMID: 27662550; PMCID: PMC5279958.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    69. A randomized controlled clinical trial on the impact of CCR5 blockade with maraviroc in early infection on T-cell dynamics. Medicine (Baltimore). 2016 Nov; 95(44):e5315. Karris MY, Umlauf A, Vaida F, Richman D, Little S, Smith D. PMID: 27858912; PMCID: PMC5591160.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    70. Viral load criteria and threshold optimization to improve HIV incidence assay characteristics. AIDS. 2016 09 24; 30(15):2361-71. Kassanjee R, Pilcher CD, Busch MP, Murphy G, Facente SN, Keating SM, Mckinney E, Marson K, Price MA, Martin JN, Little SJ, Hecht FM, Kallas EG, Welte A, Consortium for the Evaluation and Performance of HIV Incidence Assays (CEPHIA). PMID: 27454561; PMCID: PMC5024345.
      View in: PubMed   Mentions: 27     Fields:    Translation:Humans
    71. Rapid HIV Viral Load Suppression in those Initiating Antiretroviral Therapy at First Visit after HIV Diagnosis. Sci Rep. 2016 09 06; 6:32947. Hoenigl M, Chaillon A, Moore DJ, Morris SR, Mehta SR, Gianella S, Amico KR, Little SJ. PMID: 27597312; PMCID: PMC5011704.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCells
    72. Asymptomatic CMV Replication During Early Human Immunodeficiency Virus (HIV) Infection Is Associated With Lower CD4/CD8 Ratio During HIV Treatment. Clin Infect Dis. 2016 Dec 01; 63(11):1517-1524. Smith DM, Nakazawa M, Freeman ML, Anderson CM, Oliveira MF, Little SJ, Gianella S. PMID: 27601222; PMCID: PMC5106612.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    73. How can we detect HIV during the acute or primary stage of infection? Expert Rev Mol Diagn. 2016 10; 16(10):1049-1051. Hoenigl M, Little SJ. PMID: 27541993; PMCID: PMC5137792.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    74. Screening for acute HIV infection in community-based settings: Cost-effectiveness and impact on transmissions. J Infect. 2016 11; 73(5):476-484. Hoenigl M, Chaillon A, Mehta SR, Smith DM, Graff-Zivin J, Little SJ. PMID: 27521468; PMCID: PMC5143169.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    75. A practical online tool to estimate antiretroviral coverage for HIV infected and susceptible populations needed to reduce local HIV epidemics. Sci Rep. 2016 06 24; 6:28707. Chaillon A, Hoenigl M, Mehta SR, Weibel N, Little SJ, Smith DM. PMID: 27337983; PMCID: PMC4919622.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansPHPublic Health
    76. Characterizing the multiplicity of HIV founder variants during sexual transmission among MSM. Virus Evol. 2016 Jan; 2(1):vew012. Chaillon A, Gianella S, Little SJ, Caballero G, Barin F, Kosakovsky Pond S, Richman DD, Smith DM, Mehta SR. PMID: 30186625; PMCID: PMC6118227.
      View in: PubMed   Mentions: 7  
    77. HIV Infection Rates and Risk Behavior among Young Men undergoing community-based Testing in San Diego. Sci Rep. 2016 05 16; 6:25927. Hoenigl M, Chaillon A, Morris SR, Little SJ. PMID: 27181715; PMCID: PMC4867437.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansPHPublic Health
    78. Using HIV Sequence and Epidemiologic Data to Assess the Effect of Self-referral Testing for Acute HIV Infection on Incident Diagnoses in San Diego, California. Clin Infect Dis. 2016 07 01; 63(1):101-107. Mehta SR, Murrell B, Anderson CM, Kosakovsky Pond SL, Wertheim JO, Young JA, Freitas L, Richman DD, Mathews WC, Scheffler K, Little SJ, Smith DM. PMID: 27174704; PMCID: PMC4901863.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCellsPHPublic Health
    79. CD4/CD8 Cell Ratio in Acute HIV Infection and the Impact of Early Antiretroviral Therapy. Clin Infect Dis. 2016 08 01; 63(3):425-6. Hoenigl M, Chaillon A, Little SJ. PMID: 27143670; PMCID: PMC4946020.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    80. Clear Links Between Starting Methamphetamine and Increasing Sexual Risk Behavior: A Cohort Study Among Men Who Have Sex With Men. . 2016 Apr 15; 71(5):551-7. Hoenigl M, Chaillon A, Moore DJ, Morris SR, Smith DM, Little SJ. PMID: 26536321; PMCID: PMC4788567.
      View in: PubMed   Mentions: 55  Translation:Humans
    81. Replication of Human Herpesviruses Is Associated with Higher HIV DNA Levels during Antiretroviral Therapy Started at Early Phases of HIV Infection. J Virol. 2016 Apr; 90(8):3944-3952. Gianella S, Anderson CM, Var SR, Oliveira MF, Lada SM, Vargas MV, Massanella M, Little SJ, Richman DD, Strain MC, Pérez-Santiago J, Smith DM. PMID: 26842469; PMCID: PMC4810527.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansCells
    82. Characterization of HIV Transmission in South-East Austria. PLoS One. 2016; 11(3):e0151478. Hoenigl M, Chaillon A, Kessler HH, Haas B, Stelzl E, Weninger K, Little SJ, Mehta SR. PMID: 26967154; PMCID: PMC4788428.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    83. Neurobehavioral Disturbances During Acute and Early HIV Infection. Cogn Behav Neurol. 2016 Mar; 29(1):1-10. Kamat R, Doyle KL, Iudicello JE, Morgan EE, Morris S, Smith DM, Little SJ, Grant I, Woods SP, Translational Methamphetamine AIDS Research Center (TMARC) Group. PMID: 27008244; PMCID: PMC4806542.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    84. Signs or Symptoms of Acute HIV Infection in a Cohort Undergoing Community-Based Screening. Emerg Infect Dis. 2016 Mar; 22(3):532-4. Hoenigl M, Green N, Camacho M, Gianella S, Mehta SR, Smith DM, Little SJ. PMID: 26890854; PMCID: PMC4766914.
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    85. Prevalence of Transmitted HIV Drug Resistance Among Recently Infected Persons in San Diego, CA 1996-2013. . 2016 Feb 01; 71(2):228-36. Panichsillapakit T, Smith DM, Wertheim JO, Richman DD, Little SJ, Mehta SR. PMID: 26413846; PMCID: PMC4712087.
      View in: PubMed   Mentions: 22  Translation:HumansCells
    86. Colorectal Disorders in Acute Human Immunodeficiency Virus Infection: A Case Series. Open Forum Infect Dis. 2016 Jan; 3(1):ofw014. Panichsillapakit T, Patel D, Santangelo J, Richman DD, Little SJ, Smith DM. PMID: 26925432; PMCID: PMC4766383.
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    87. Distinct cytokine/chemokine network in semen and blood characterize different stages of HIV infection. AIDS. 2016 Jan; 30(2):193-201. Vanpouille C, Introini A, Morris SR, Margolis L, Daar ES, Dube MP, Little SJ, Smith DM, Lisco A, Gianella S. PMID: 26558730; PMCID: PMC4862605.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    88. RETRACTED: Investigation of the GeneXpert® CT/NG assay for use with male pharyngeal and rectal swabs. Int J STD AIDS. 2016 Jan 01; 956462416665059. Geiger R, Smith DM, Little SJ, Mehta SR. PMID: 27510643.
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    89. High Prevalence of Covert Infection With Gastrointestinal Helminths in Cats. J Am Anim Hosp Assoc. 2015 Nov-Dec; 51(6):359-64. Little S, Adolph C, Downie K, Snider T, Reichard M. PMID: 26535453.
      View in: PubMed   Mentions: 9     Fields:    Translation:Animals
    90. Costs per Diagnosis of Acute HIV Infection in Community-based Screening Strategies: A Comparative Analysis of Four Screening Algorithms. Clin Infect Dis. 2016 Feb 15; 62(4):501-511. Hoenigl M, Graff-Zivin J, Little SJ. PMID: 26508512; PMCID: PMC4725382.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCellsPHPublic Health
    91. No evidence of posttreatment control after early initiation of antiretroviral therapy. AIDS. 2015 Oct 23; 29(16):2093-7. Gianella S, Anderson CM, Richman DD, Smith DM, Little SJ. PMID: 26544575; PMCID: PMC4638137.
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    92. Risk Behavior and Sexually Transmitted Infections Among Transgender Women and Men Undergoing Community-Based Screening for Acute and Early HIV Infection in San Diego. Medicine (Baltimore). 2015 Oct; 94(41):e1830. Green N, Hoenigl M, Morris S, Little SJ. PMID: 26469928; PMCID: PMC4616789.
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    93. Repeat HIV-testing is associated with an increase in behavioral risk among men who have sex with men: a cohort study. BMC Med. 2015 Sep 11; 13:218. Hoenigl M, Anderson CM, Green N, Mehta SR, Smith DM, Little SJ. PMID: 26444673; PMCID: PMC4596465.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansPHPublic Health
    94. Methamphetamine Use in HIV-infected Individuals Affects T-cell Function and Viral Outcome during Suppressive Antiretroviral Therapy. Sci Rep. 2015 Aug 24; 5:13179. Massanella M, Gianella S, Schrier R, Dan JM, Pérez-Santiago J, Oliveira MF, Richman DD, Little SJ, Benson CA, Daar ES, Dube MP, Haubrich RH, Smith DM, Morris SR. PMID: 26299251; PMCID: PMC4547398.
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    95. HIV Transmission Networks in the San Diego-Tijuana Border Region. EBioMedicine. 2015 Oct; 2(10):1456-63. Mehta SR, Wertheim JO, Brouwer KC, Wagner KD, Chaillon A, Strathdee S, Patterson TL, Rangel MG, Vargas M, Murrell B, Garfein R, Little SJ, Smith DM. PMID: 26629540; PMCID: PMC4634195.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCellsPHPublic Health
    96. Seminal Shedding of CMV and HIV Transmission among Men Who Have Sex with Men. Int J Environ Res Public Health. 2015 Jul 07; 12(7):7585-92. Gianella S, Scheffler K, Mehta SR, Little SJ, Freitas L, Morris SR, Smith DM. PMID: 26198239; PMCID: PMC4515676.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    97. Risk Factors for Acute and Early HIV Infection Among Men Who Have Sex With Men (MSM) in San Diego, 2008 to 2014: A Cohort Study. Medicine (Baltimore). 2015 Jul; 94(30):e1242. Hoenigl M, Green N, Mehta SR, Little SJ. PMID: 26222863; PMCID: PMC4554110.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    98. Development and validation of the San Diego Early Test Score to predict acute and early HIV infection risk in men who have sex with men. Clin Infect Dis. 2015 Aug 01; 61(3):468-75. Hoenigl M, Weibel N, Mehta SR, Anderson CM, Jenks J, Green N, Gianella S, Smith DM, Little SJ. PMID: 25904374; PMCID: PMC4542926.
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    99. Influence of the timing of antiretroviral therapy on the potential for normalization of immune status in human immunodeficiency virus 1-infected individuals. JAMA Intern Med. 2015 Jan; 175(1):88-99. Okulicz JF, Le TD, Agan BK, Camargo JF, Landrum ML, Wright E, Dolan MJ, Ganesan A, Ferguson TM, Smith DM, Richman DD, Little SJ, Clark RA, He W, Ahuja SK. PMID: 25419650; PMCID: PMC4286496.
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    100. Independent assessment of candidate HIV incidence assays on specimens in the CEPHIA repository. AIDS. 2014 Oct 23; 28(16):2439-49. Kassanjee R, Pilcher CD, Keating SM, Facente SN, McKinney E, Price MA, Martin JN, Little S, Hecht FM, Kallas EG, Welte A, Busch MP, Murphy G, Consortium for the Evaluation and Performance of HIV Incidence Assays (CEPHIA). PMID: 25144218; PMCID: PMC4210690.
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    101. Individualized diagnosis interventions can add significant effectiveness in reducing human immunodeficiency virus incidence among men who have sex with men: insights from Southern California. Ann Epidemiol. 2015 Jan; 25(1):1-6. Khanna A, Goodreau SM, Wohlfeiler D, Daar E, Little S, Gorbach PM. PMID: 25453725; PMCID: PMC4255290.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    102. Pre-exposure prophylaxis accessibility research and evaluation (PrEPARE Study). AIDS Behav. 2014 Sep; 18(9):1722-5. King HL, Keller SB, Giancola MA, Rodriguez DA, Chau JJ, Young JA, Little SJ, Smith DM. PMID: 25017425; PMCID: PMC4127131.
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    103. Emergence of individual HIV-specific CD8 T cell responses during primary HIV-1 infection can determine long-term disease outcome. J Virol. 2014 Nov; 88(21):12793-801. Streeck H, Lu R, Beckwith N, Milazzo M, Liu M, Routy JP, Little S, Jessen H, Kelleher AD, Hecht F, Sekaly RP, Alter G, Heckerman D, Carrington M, Rosenberg ES, Altfeld M. PMID: 25165102; PMCID: PMC4248916.
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    104. Modeling the impact of post-diagnosis behavior change on HIV prevalence in Southern California men who have sex with men (MSM). AIDS Behav. 2014 Aug; 18(8):1523-31. Khanna AS, Goodreau SM, Gorbach PM, Daar E, Little SJ. PMID: 24165985; PMCID: PMC4004722.
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    105. Human APOBEC3 induced mutation of human immunodeficiency virus type-1 contributes to adaptation and evolution in natural infection. PLoS Pathog. 2014 Jul; 10(7):e1004281. Kim EY, Lorenzo-Redondo R, Little SJ, Chung YS, Phalora PK, Maljkovic Berry I, Archer J, Penugonda S, Fischer W, Richman DD, Bhattacharya T, Malim MH, Wolinsky SM. PMID: 25080100; PMCID: PMC4117599.
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    106. Impaired Nef function is associated with early control of HIV-1 viremia. J Virol. 2014 Sep 01; 88(17):10200-13. Kuang XT, Li X, Anmole G, Mwimanzi P, Shahid A, Le AQ, Chong L, Qian H, Miura T, Markle T, Baraki B, Connick E, Daar ES, Jessen H, Kelleher AD, Little S, Markowitz M, Pereyra F, Rosenberg ES, Walker BD, Ueno T, Brumme ZL, Brockman MA. PMID: 24965469; PMCID: PMC4136354.
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    107. Using HIV networks to inform real time prevention interventions. PLoS One. 2014; 9(6):e98443. Little SJ, Kosakovsky Pond SL, Anderson CM, Young JA, Wertheim JO, Mehta SR, May S, Smith DM. PMID: 24901437; PMCID: PMC4047027.
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    108. Geography should not be destiny: focusing HIV/AIDS implementation research and programs on microepidemics in US neighborhoods. Am J Public Health. 2014 May; 104(5):775-80. Nunn A, Yolken A, Cutler B, Trooskin S, Wilson P, Little S, Mayer K. PMID: 24716570; PMCID: PMC3987607.
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    109. Cytomegalovirus replication in semen is associated with higher levels of proviral HIV DNA and CD4+ T cell activation during antiretroviral treatment. J Virol. 2014 Jul; 88(14):7818-27. Gianella S, Massanella M, Richman DD, Little SJ, Spina CA, Vargas MV, Lada SM, Daar ES, Dube MP, Haubrich RH, Morris SR, Smith DM, California Collaborative Treatment Group 592 Team. PMID: 24789781; PMCID: PMC4097769.
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    110. Ensuring privacy in the study of pathogen genetics. Lancet Infect Dis. 2014 Aug; 14(8):773-777. Mehta SR, Vinterbo SA, Little SJ. PMID: 24721230; PMCID: PMC4111774.
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    111. Predictors of virologic response in persons who start antiretroviral therapy during recent HIV infection. AIDS. 2014 Mar 27; 28(6):841-9. Karris MY, Kao YT, Patel D, Dawson M, Woods SP, Vaida F, Spina C, Richman D, Little S, Smith DM. PMID: 24401640; PMCID: PMC4049563.
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    112. Relationships among measures of balance, gait, and community integration in people with brain injury. J Head Trauma Rehabil. 2014 Mar-Apr; 29(2):117-24. Perry SB, Woollard J, Little S, Shroyer K. PMID: 23474884.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    113. Real-world impact of neurocognitive deficits in acute and early HIV infection. J Neurovirol. 2013 Dec; 19(6):565-73. Doyle KL, Morgan EE, Morris S, Smith DM, Little S, Iudicello JE, Blackstone K, Moore DJ, Grant I, Letendre SL, Woods SP, Translational Methamphetamine AIDS Research Center (TMARC) Group. PMID: 24277439; PMCID: PMC3865175.
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    114. Incidence and prevalence of intrasubtype HIV-1 dual infection in at-risk men in the United States. J Infect Dis. 2014 Apr 01; 209(7):1032-8. Wagner GA, Pacold ME, Kosakovsky Pond SL, Caballero G, Chaillon A, Rudolph AE, Morris SR, Little SJ, Richman DD, Smith DM. PMID: 24273040; PMCID: PMC3952674.
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    115. Dual-mixed HIV-1 coreceptor tropism and HIV-associated neurocognitive deficits. J Neurovirol. 2013 Oct; 19(5):488-94. Morris SR, Woods SP, Deutsch R, Little SJ, Wagner G, Morgan EE, Heaton RK, Letendre SL, Grant I, Smith DM. PMID: 24078557; PMCID: PMC3921071.
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    116. Dynamics of viral evolution and neutralizing antibody response after HIV-1 superinfection. J Virol. 2013 Dec; 87(23):12737-44. Chaillon A, Wagner GA, Hepler NL, Little SJ, Kosakovsky Pond SL, Caballero G, Pacold ME, Phung P, Wrin T, Richman DD, Wertheim JO, Smith DM. PMID: 24049166; PMCID: PMC3838120.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    117. Virologic correlates of anti-CMV IgG levels in HIV-1-infected men. J Infect Dis. 2014 Feb 01; 209(3):452-6. Gianella S, Morris SR, Tatro E, Vargas MV, Haubrich RH, Daar ES, Dube MP, Richman DD, Little SJ, Smith DM. PMID: 23964106; PMCID: PMC3883163.
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    118. Differential gene expression in HIV-infected individuals following ART. Antiviral Res. 2013 Nov; 100(2):420-8. Massanella M, Singhania A, Beliakova-Bethell N, Pier R, Lada SM, White CH, Pérez-Santiago J, Blanco J, Richman DD, Little SJ, Woelk CH. PMID: 23933117; PMCID: PMC3899918.
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    119. Gut Lactobacillales are associated with higher CD4 and less microbial translocation during HIV infection. AIDS. 2013 Jul 31; 27(12):1921-31. Pérez-Santiago J, Gianella S, Massanella M, Spina CA, Karris MY, Var SR, Patel D, Jordan PS, Young JA, Little SJ, Richman DD, Smith DM. PMID: 24180001; PMCID: PMC3816380.
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    120. HIV-1 clade B pol evolution following primary infection. PLoS One. 2013; 8(6):e68188. Hightower GK, May SJ, Pérez-Santiago J, Pacold ME, Wagner GA, Little SJ, Richman DD, Mehta SR, Smith DM, Pond SL. PMID: 23840830; PMCID: PMC3695957.
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    121. Reply to Mounzer and DiNubile. J Infect Dis. 2013 Aug 15; 208(4):711-2. Morris SR, Smith DM, Little SJ, Gianella S. PMID: 23667136; PMCID: PMC3719903.
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    122. Using ultradeep pyrosequencing to study HIV-1 coreceptor usage in primary and dual infection. J Infect Dis. 2013 Jul 15; 208(2):271-4. Wagner GA, Pacold ME, Vigil E, Caballero G, Morris SR, Kosakovsky Pond SL, Little SJ, Richman DD, Gianella S, Smith DM. PMID: 23599311; PMCID: PMC3685231.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    123. Shedding of HIV and human herpesviruses in the semen of effectively treated HIV-1-infected men who have sex with men. Clin Infect Dis. 2013 Aug; 57(3):441-7. Gianella S, Smith DM, Vargas MV, Little SJ, Richman DD, Daar ES, Dube MP, Zhang F, Ginocchio CC, Haubrich RH, Morris SR, CCTG 592 Team. PMID: 23595831; PMCID: PMC3703105.
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    124. Enhanced CD4+ T-cell recovery with earlier HIV-1 antiretroviral therapy. N Engl J Med. 2013 Jan 17; 368(3):218-30. Le T, Wright EJ, Smith DM, He W, Catano G, Okulicz JF, Young JA, Clark RA, Richman DD, Little SJ, Ahuja SK. PMID: 23323898; PMCID: PMC3657555.
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    125. Herpes viruses and HIV-1 drug resistance mutations influence the virologic and immunologic milieu of the male genital tract. AIDS. 2013 Jan 02; 27(1):39-47. Gianella S, Morris SR, Anderson C, Spina CA, Vargas MV, Young JA, Richman DD, Little SJ, Smith DM. PMID: 22739399; PMCID: PMC3769229.
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    126. Cytomegalovirus DNA in semen and blood is associated with higher levels of proviral HIV DNA. J Infect Dis. 2013 Mar 15; 207(6):898-902. Gianella S, Anderson CM, Vargas MV, Richman DD, Little SJ, Morris SR, Smith DM. PMID: 23275608; PMCID: PMC3571441.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansCells
    127. Substance use is a risk factor for neurocognitive deficits and neuropsychiatric distress in acute and early HIV infection. J Neurovirol. 2013 Feb; 19(1):65-74. Weber E, Morgan EE, Iudicello JE, Blackstone K, Grant I, Ellis RJ, Letendre SL, Little S, Morris S, Smith DM, Moore DJ, Woods SP, TMARC Group. PMID: 23250704; PMCID: PMC3568179.
      View in: PubMed   Mentions: 44     Fields:    Translation:Humans
    128. Role of seminal shedding of herpesviruses in HIV Type 1 Transmission. J Infect Dis. 2013 Jan 15; 207(2):257-61. Gianella S, Morris SR, Vargas MV, Young JA, Callahan B, Richman DD, Little SJ, Smith DM. PMID: 23148284; PMCID: PMC3532824.
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    129. Impact of seminal cytomegalovirus replication on HIV-1 dynamics between blood and semen. J Med Virol. 2012 Nov; 84(11):1703-9. Gianella S, Mehta SR, Strain MC, Young JA, Vargas MV, Little SJ, Richman DD, Kosakovsky Pond SL, Smith DM. PMID: 22997072; PMCID: PMC3472447.
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    130. Sexual transmission of predicted CXCR4-tropic HIV-1 likely originating from the source partner's seminal cells. Virology. 2012 Dec 05; 434(1):2-4. Gianella S, Mehta SR, Young JA, Vargas MV, Little SJ, Richman DD, Kosakovsky Pond SL, Smith DM. PMID: 23040890; PMCID: PMC3485073.
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    131. Higher HIV-1 genetic diversity is associated with AIDS and neuropsychological impairment. Virology. 2012 Nov 25; 433(2):498-505. Hightower GK, Wong JK, Letendre SL, Umlauf AA, Ellis RJ, Ignacio CC, Heaton RK, Collier AC, Marra CM, Clifford DB, Gelman BB, McArthur JC, Morgello S, Simpson DM, McCutchan JA, Grant I, Little SJ, Richman DD, Kosakovsky Pond SL, Smith DM, CHARTER Study Group. PMID: 22999095; PMCID: PMC3466337.
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    132. The design, synthesis, in silico ADME profiling, antiplasmodial and antimycobacterial evaluation of new arylamino quinoline derivatives. Eur J Med Chem. 2012 Nov; 57:259-67. Tukulula M, Little S, Gut J, Rosenthal PJ, Wan B, Franzblau SG, Chibale K. PMID: 23064162.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    133. A combined screening platform for HIV treatment failure and resistance. PLoS One. 2012; 7(4):e35401. Tilghman MW, May S, Pérez-Santiago J, Ignacio CC, Little SJ, Richman DD, Smith DM. PMID: 22563383; PMCID: PMC3338506.
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    134. Associations between phylogenetic clustering and HLA profile among HIV-infected individuals in San Diego, California. J Infect Dis. 2012 May 15; 205(10):1529-33. Mehta SR, Kosakovsky Pond SL, Young JA, Richman D, Little S, Smith DM. PMID: 22448013; PMCID: PMC3415817.
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    135. Cost savings associated with testing of antibodies, antigens, and nucleic acids for diagnosis of acute HIV infection. J Clin Microbiol. 2012 Jun; 50(6):1874-8. Karris MY, Anderson CM, Morris SR, Smith DM, Little SJ. PMID: 22442319; PMCID: PMC3372146.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansPHPublic Health
    136. Clinical, virologic, and immunologic correlates of HIV-1 intraclade B dual infection among men who have sex with men. AIDS. 2012 Jan 14; 26(2):157-65. Pacold ME, Pond SL, Wagner GA, Delport W, Bourque DL, Richman DD, Little SJ, Smith DM. PMID: 22045341; PMCID: PMC3807679.
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    137. The setpoint study (ACTG A5217): effect of immediate versus deferred antiretroviral therapy on virologic set point in recently HIV-1-infected individuals. J Infect Dis. 2012 Jan 01; 205(1):87-96. Hogan CM, Degruttola V, Sun X, Fiscus SA, Del Rio C, Hare CB, Markowitz M, Connick E, Macatangay B, Tashima KT, Kallungal B, Camp R, Morton T, Daar ES, Little S, A5217 Study Team. PMID: 22180621; PMCID: PMC3242744.
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    138. Associations between virologic and immunologic dynamics in blood and in the male genital tract. J Virol. 2012 Feb; 86(3):1307-15. Gianella S, Strain MC, Rought SE, Vargas MV, Little SJ, Richman DD, Spina CA, Smith DM. PMID: 22114342; PMCID: PMC3264378.
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    139. Using HIV transmission networks to investigate community effects in HIV prevention trials. PLoS One. 2011; 6(11):e27775. Wertheim JO, Kosakovsky Pond SL, Little SJ, De Gruttola V. PMID: 22114692; PMCID: PMC3218056.
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    140. High-risk behaviors associated with injection drug use among recently HIV-infected men who have sex with men in San Diego, CA. AIDS Behav. 2011 Oct; 15(7):1561-9. Ghanem A, Little SJ, Drumright L, Liu L, Morris S, Garfein RS. PMID: 21607643; PMCID: PMC4394837.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    141. Upregulation of BST-2/Tetherin by HIV infection in vivo. J Virol. 2011 Oct; 85(20):10659-68. Homann S, Smith D, Little S, Richman D, Guatelli J. PMID: 21849457; PMCID: PMC3187519.
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    142. Identifying the early post-HIV antibody seroconversion period. J Infect Dis. 2011 Aug 15; 204(4):526-33. Hecht FM, Wellman R, Busch MP, Pilcher CD, Norris PJ, Margolick JB, Collier AC, Little SJ, Markowitz M, Routy JP, Holte S, Acute Infection Early Disease Research Program. PMID: 21791654; PMCID: PMC3144168.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    143. MSM: resurgent epidemics. Curr Opin HIV AIDS. 2011 Jul; 6(4):326-32. Morris SR, Little SJ. PMID: 21537172; PMCID: PMC6075729.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    144. Detection of minority resistance during early HIV-1 infection: natural variation and spurious detection rather than transmission and evolution of multiple viral variants. J Virol. 2011 Aug; 85(16):8359-67. Gianella S, Delport W, Pacold ME, Young JA, Choi JY, Little SJ, Richman DD, Kosakovsky Pond SL, Smith DM. PMID: 21632754; PMCID: PMC3147985.
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    145. Evaluation of pooled rapid HIV antibody screening of patients admitted to a San Diego Hospital. J Virol Methods. 2011 Jun; 174(1-2):94-8. Mehta SR, Nguyen VT, Osorio G, Little S, Smith DM. PMID: 21513744; PMCID: PMC3095723.
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    146. Behaviors of recently HIV-infected men who have sex with men in the year postdiagnosis: effects of drug use and partner types. J Acquir Immune Defic Syndr. 2011 Feb 01; 56(2):176-82. Gorbach PM, Weiss RE, Jeffries R, Javanbakht M, Drumright LN, Daar ES, Little SJ. PMID: 21119524; PMCID: PMC3023009.
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    147. Sex, race, and geographic region influence clinical outcomes following primary HIV-1 infection. J Infect Dis. 2011 Feb 15; 203(4):442-51. Meditz AL, MaWhinney S, Allshouse A, Feser W, Markowitz M, Little S, Hecht R, Daar ES, Collier AC, Margolick J, Kilby JM, Routy JP, Conway B, Kaldor J, Levy J, Schooley R, Cooper DA, Altfeld M, Richman D, Connick E. PMID: 21245157; PMCID: PMC3071223.
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    148. Neurocognitive functioning in acute or early HIV infection. J Neurovirol. 2011 Feb; 17(1):50-7. Moore DJ, Letendre SL, Morris S, Umlauf A, Deutsch R, Smith DM, Little S, Rooney A, Franklin DR, Gouaux B, Leblanc S, Rosario D, Fennema-Notestine C, Heaton RK, Ellis RJ, Atkinson JH, Grant I, CHARTER Group. PMID: 21165782; PMCID: PMC3032208.
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    149. The major genetic determinants of HIV-1 control affect HLA class I peptide presentation. Science. 2010 Dec 10; 330(6010):1551-7. International HIV Controllers Study, Pereyra F, Jia X, McLaren PJ, Telenti A, de Bakker PI, Walker BD, Ripke S, Brumme CJ, Pulit SL, Carrington M, Kadie CM, Carlson JM, Heckerman D, Graham RR, Plenge RM, Deeks SG, Gianniny L, Crawford G, Sullivan J, Gonzalez E, Davies L, Camargo A, Moore JM, Beattie N, Gupta S, Crenshaw A, Burtt NP, Guiducci C, Gupta N, Gao X, Qi Y, Yuki Y, Piechocka-Trocha A, Cutrell E, Rosenberg R, Moss KL, Lemay P, O'Leary J, Schaefer T, Verma P, Toth I, Block B, Baker B, Rothchild A, Lian J, Proudfoot J, Alvino DM, Vine S, Addo MM, Allen TM, Altfeld M, Henn MR, Le Gall S, Streeck H, Haas DW, Kuritzkes DR, Robbins GK, Shafer RW, Gulick RM, Shikuma CM, Haubrich R, Riddler S, Sax PE, Daar ES, Ribaudo HJ, Agan B, Agarwal S, Ahern RL, Allen BL, Altidor S, Altschuler EL, Ambardar S, Anastos K, Anderson B, Anderson V, Andrady U, Antoniskis D, Bangsberg D, Barbaro D, Barrie W, Bartczak J, Barton S, Basden P, Basgoz N, Bazner S, Bellos NC, Benson AM, Berger J, Bernard NF, Bernard AM, Birch C, Bodner SJ, Bolan RK, Boudreaux ET, Bradley M, Braun JF, Brndjar JE, Brown SJ, Brown K, Brown ST, Burack J, Bush LM, Cafaro V, Campbell O, Campbell J, Carlson RH, Carmichael JK, Casey KK, Cavacuiti C, Celestin G, Chambers ST, Chez N, Chirch LM, Cimoch PJ, Cohen D, Cohn LE, Conway B, Cooper DA, Cornelson B, Cox DT, Cristofano MV, Cuchural G, Czartoski JL, Dahman JM, Daly JS, Davis BT, Davis K, Davod SM, DeJesus E, Dietz CA, Dunham E, Dunn ME, Ellerin TB, Eron JJ, Fangman JJ, Farel CE, Ferlazzo H, Fidler S, Fleenor-Ford A, Frankel R, Freedberg KA, French NK, Fuchs JD, Fuller JD, Gaberman J, Gallant JE, Gandhi RT, Garcia E, Garmon D, Gathe JC, Gaultier CR, Gebre W, Gilman FD, Gilson I, Goepfert PA, Gottlieb MS, Goulston C, Groger RK, Gurley TD, Haber S, Hardwicke R, Hardy WD, Harrigan PR, Hawkins TN, Heath S, Hecht FM, Henry WK, Hladek M, Hoffman RP, Horton JM, Hsu RK, Huhn GD, Hunt P, Hupert MJ, Illeman ML, Jaeger H, Jellinger RM, John M, Johnson JA, Johnson KL, Johnson H, Johnson K, Joly J, Jordan WC, Kauffman CA, Khanlou H, Killian RK, Kim AY, Kim DD, Kinder CA, Kirchner JT, Kogelman L, Kojic EM, Korthuis PT, Kurisu W, Kwon DS, LaMar M, Lampiris H, Lanzafame M, Lederman MM, Lee DM, Lee JM, Lee MJ, Lee ET, Lemoine J, Levy JA, Llibre JM, Liguori MA, Little SJ, Liu AY, Lopez AJ, Loutfy MR, Loy D, Mohammed DY, Man A, Mansour MK, Marconi VC, Markowitz M, Marques R, Martin JN, Martin HL, Mayer KH, McElrath MJ, McGhee TA, McGovern BH, McGowan K, McIntyre D, Mcleod GX, Menezes P, Mesa G, Metroka CE, Meyer-Olson D, Miller AO, Montgomery K, Mounzer KC, Nagami EH, Nagin I, Nahass RG, Nelson MO, Nielsen C, Norene DL, O'Connor DH, Ojikutu BO, Okulicz J, Oladehin OO, Oldfield EC, Olender SA, Ostrowski M, Owen WF, Pae E, Parsonnet J, Pavlatos AM, Perlmutter AM, Pierce MN, Pincus JM, Pisani L, Price LJ, Proia L, Prokesch RC, Pujet HC, Ramgopal M, Rathod A, Rausch M, Ravishankar J, Rhame FS, Richards CS, Richman DD, Rodes B, Rodriguez M, Rose RC, Rosenberg ES, Rosenthal D, Ross PE, Rubin DS, Rumbaugh E, Saenz L, Salvaggio MR, Sanchez WC, Sanjana VM, Santiago S, Schmidt W, Schuitemaker H, Sestak PM, Shalit P, Shay W, Shirvani VN, Silebi VI, Sizemore JM, Skolnik PR, Sokol-Anderson M, Sosman JM, Stabile P, Stapleton JT, Starrett S, Stein F, Stellbrink HJ, Sterman FL, Stone VE, Stone DR, Tambussi G, Taplitz RA, Tedaldi EM, Telenti A, et al. PMID: 21051598; PMCID: PMC3235490.
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    150. Comparison of methods to detect HIV dual infection. AIDS Res Hum Retroviruses. 2010 Dec; 26(12):1291-8. Pacold M, Smith D, Little S, Cheng PM, Jordan P, Ignacio C, Richman D, Pond SK. PMID: 20954840; PMCID: PMC3011997.
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    151. Clinical management of acute HIV infection: best practice remains unknown. J Infect Dis. 2010 Oct 15; 202 Suppl 2:S278-88. Bell SK, Little SJ, Rosenberg ES. PMID: 20846034; PMCID: PMC6037306.
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    152. Response to Comment on "The Origins of Sexually Transmitted HIV Among Men Who Have Sex with Men" Sci Transl Med. 2010 Sep; 2(50):501r1. Smith D, Delport W, Butler D, Little S, Richman D, Pond SK. PMID: 21532938; PMCID: PMC3083242.
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    153. Evaluation of an HIV nucleic acid testing program with automated Internet and voicemail systems to deliver results. Ann Intern Med. 2010 Jun 15; 152(12):778-85. Morris SR, Little SJ, Cunningham T, Garfein RS, Richman DD, Smith DM. PMID: 20547906; PMCID: PMC2922925.
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    154. Impaired replication capacity of acute/early viruses in persons who become HIV controllers. J Virol. 2010 Aug; 84(15):7581-91. Miura T, Brumme ZL, Brockman MA, Rosato P, Sela J, Brumme CJ, Pereyra F, Kaufmann DE, Trocha A, Block BL, Daar ES, Connick E, Jessen H, Kelleher AD, Rosenberg E, Markowitz M, Schafer K, Vaida F, Iwamoto A, Little S, Walker BD. PMID: 20504921; PMCID: PMC2897600.
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    155. Developing and evaluating comprehensive HIV infection control strategies: issues and challenges. Clin Infect Dis. 2010 May 15; 50 Suppl 3:S102-7. DeGruttola V, Smith DM, Little SJ, Miller V. PMID: 20397937; PMCID: PMC2913596.
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    156. Safety and immunogenicity of therapeutic DNA vaccination in individuals treated with antiretroviral therapy during acute/early HIV-1 infection. PLoS One. 2010 May 10; 5(5):e10555. Rosenberg ES, Graham BS, Chan ES, Bosch RJ, Stocker V, Maenza J, Markowitz M, Little S, Sax PE, Collier AC, Nabel G, Saindon S, Flynn T, Kuritzkes D, Barouch DH, AIDS Clinical Trials Group A5187 Team. PMID: 20479938; PMCID: PMC2866663.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansCellsPHPublic HealthCTClinical Trials
    157. The virologic and immunologic effects of cyclosporine as an adjunct to antiretroviral therapy in patients treated during acute and early HIV-1 infection. J Infect Dis. 2010 May 01; 201(9):1298-302. Markowitz M, Vaida F, Hare CB, Boden D, Mohri H, Hecht FM, Kalayjian RC, Conrad A, Mildvan D, Aberg J, Hogan C, Kilby JM, Balfour HH, Schafer K, Richman D, Little S. PMID: 20235838; PMCID: PMC2851487.
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    158. The origins of sexually transmitted HIV among men who have sex with men. Sci Transl Med. 2010 Feb 10; 2(18):18re1. Butler DM, Delport W, Kosakovsky Pond SL, Lakdawala MK, Cheng PM, Little SJ, Richman DD, Smith DM. PMID: 20371483; PMCID: PMC2945226.
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    159. Gene expression before HAART initiation predicts HIV-infected individuals at risk of poor CD4+ T-cell recovery. AIDS. 2010 Jan 16; 24(2):217-22. Woelk CH, Beliakova-Bethell N, Goicoechea M, Zhao Y, Du P, Rought SE, Lozach J, Pérez-Santiago J, Richman DD, Smith DM, Little SJ. PMID: 19952713; PMCID: PMC2915828.
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    160. The use of pooled viral load testing to identify antiretroviral treatment failure. AIDS. 2009 Oct 23; 23(16):2151-8. Smith DM, May SJ, Pérez-Santiago J, Strain MC, Ignacio CC, Haubrich RH, Richman DD, Benson CA, Little SJ. PMID: 19730348; PMCID: PMC2915784.
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    161. Antiretroviral therapy in acute and recent HIV infection: a prospective multicenter stratified trial of intentionally interrupted treatment. AIDS. 2009 Sep 24; 23(15):1987-95. Volberding P, Demeter L, Bosch RJ, Aga E, Pettinelli C, Hirsch M, Vogler M, Martinez A, Little S, Connick E, ACTG 371 Team. PMID: 19696651; PMCID: PMC2888600.
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    162. Seroprevalence of feline leukemia virus and feline immunodeficiency virus infection among cats in Canada. Can Vet J. 2009 Jun; 50(6):644-8. Little S, Sears W, Lachtara J, Bienzle D. PMID: 19721785; PMCID: PMC2684053.
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    163. Human immunodeficiency virus type 1-specific CD8+ T-cell responses during primary infection are major determinants of the viral set point and loss of CD4+ T cells. J Virol. 2009 Aug; 83(15):7641-8. Streeck H, Jolin JS, Qi Y, Yassine-Diab B, Johnson RC, Kwon DS, Addo MM, Brumme C, Routy JP, Little S, Jessen HK, Kelleher AD, Hecht FM, Sekaly RP, Rosenberg ES, Walker BD, Carrington M, Altfeld M. PMID: 19458000; PMCID: PMC2708622.
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    164. Latently-infected CD4+ T cells are enriched for HIV-1 Tat variants with impaired transactivation activity. Virology. 2009 Apr 25; 387(1):98-108. Yukl S, Pillai S, Li P, Chang K, Pasutti W, Ahlgren C, Havlir D, Strain M, Günthard H, Richman D, Rice AP, Daar E, Little S, Wong JK. PMID: 19268337; PMCID: PMC4474533.
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    165. Tolerability and efficacy of PI versus NNRTI-based regimens in subjects receiving HAART during acute or early HIV infection. J Acquir Immune Defic Syndr. 2009 Mar 01; 50(3):267-75. Apuzzo LG, Vaida F, Gallant JE, Ernstrom KB, Little SJ, Routy JP, Collier AC, Conway B, Markowitz MH, Hecht FM, Walker BD, Connick E, Margolick JB. PMID: 19194317; PMCID: PMC3115738.
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    166. A public health model for the molecular surveillance of HIV transmission in San Diego, California. AIDS. 2009 Jan 14; 23(2):225-32. Smith DM, May SJ, Tweeten S, Drumright L, Pacold ME, Kosakovsky Pond SL, Pesano RL, Lie YS, Richman DD, Frost SD, Woelk CH, Little SJ. PMID: 19098493; PMCID: PMC2644048.
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    167. Controlling the HIV epidemic, without a vaccine! AIDS. 2008 Nov 30; 22(18):2554-5. DeGruttola V, Little S, Schooley R. PMID: 19005285; PMCID: PMC6037487.
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    168. Optimizing peptide matrices for identifying T-cell antigens. Cytometry A. 2008 Nov; 73(11):1071-8. Precopio ML, Butterfield TR, Casazza JP, Little SJ, Richman DD, Koup RA, Roederer M. PMID: 18781655; PMCID: PMC2586828.
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    169. Herpes simplex virus 2 serostatus and viral loads of HIV-1 in blood and semen as risk factors for HIV transmission among men who have sex with men. AIDS. 2008 Aug 20; 22(13):1667-71. Butler DM, Smith DM, Cachay ER, Hightower GK, Nugent CT, Richman DD, Little SJ. PMID: 18670228; PMCID: PMC2653089.
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    170. 2008 American Association of Feline Practitioners' feline retrovirus management guidelines. J Feline Med Surg. 2008 Jul; 10(3):300-16. Levy J, Crawford C, Hartmann K, Hofmann-Lehmann R, Little S, Sundahl E, Thayer V. PMID: 18455463.
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    171. Comparison of algorithms that interpret genotypic HIV-1 drug resistance to determine the prevalence of transmitted drug resistance. AIDS. 2008 Apr 23; 22(7):835-9. Liu L, May S, Richman DD, Hecht FM, Markowitz M, Daar ES, Routy JP, Margolick JB, Collier AC, Woelk CH, Little SJ, Smith DM. PMID: 18427201; PMCID: PMC2716722.
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    172. Antiretroviral drug resistance and risk behavior among recently HIV-infected men who have sex with men. J Acquir Immune Defic Syndr. 2008 Apr 15; 47(5):639-43. Gorbach PM, Drumright LN, Javanbakht M, Pond SL, Woelk CH, Daar ES, Little SJ. PMID: 18285715; PMCID: PMC4153748.
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    173. Herpes simplex virus type 2 acquisition during recent HIV infection does not influence plasma HIV levels. . 2008 Apr 15; 47(5):592-6. Cachay ER, Frost SD, Poon AF, Looney D, Rostami SM, Pacold ME, Richman DD, Little SJ, Smith DM. PMID: 18197122; PMCID: PMC2630881.
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    174. CCL3L1-CCR5 genotype influences durability of immune recovery during antiretroviral therapy of HIV-1-infected individuals. Nat Med. 2008 Apr; 14(4):413-20. Ahuja SK, Kulkarni H, Catano G, Agan BK, Camargo JF, He W, O'Connell RJ, Marconi VC, Delmar J, Eron J, Clark RA, Frost S, Martin J, Ahuja SS, Deeks SG, Little S, Richman D, Hecht FM, Dolan MJ. PMID: 18376407; PMCID: PMC2630879.
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    175. Persistence of transmitted drug resistance among subjects with primary human immunodeficiency virus infection. J Virol. 2008 Jun; 82(11):5510-8. Little SJ, Frost SD, Wong JK, Smith DM, Pond SL, Ignacio CC, Parkin NT, Petropoulos CJ, Richman DD. PMID: 18353964; PMCID: PMC2395184.
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    176. Dynamics of total, linear nonintegrated, and integrated HIV-1 DNA in vivo and in vitro. J Infect Dis. 2008 Feb 01; 197(3):411-9. Koelsch KK, Liu L, Haubrich R, May S, Havlir D, Günthard HF, Ignacio CC, Campos-Soto P, Little SJ, Shafer R, Robbins GK, D'Aquila RT, Kawano Y, Young K, Dao P, Spina CA, Richman DD, Wong JK. PMID: 18248304.
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    177. Treatment of acute HIV-1 infection: are we getting there? Curr Opin HIV AIDS. 2008 Jan; 3(1):67-74. Cellerai C, Little SJ, Loes SK. PMID: 19372946.
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    178. Associations between substance use, erectile dysfunction medication and recent HIV infection among men who have sex with men. AIDS Behav. 2009 Apr; 13(2):328-36. Drumright LN, Gorbach PM, Little SJ, Strathdee SA. PMID: 18064558; PMCID: PMC6075707.
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    179. Application of multicomponent reactions to antimalarial drug discovery. Part 3: discovery of aminoxazole 4-aminoquinolines with potent antiplasmodial activity in vitro. Bioorg Med Chem Lett. 2007 Sep 01; 17(17):4733-6. Musonda CC, Little S, Yardley V, Chibale K. PMID: 17644333.
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    180. Long-term persistence of transmitted HIV drug resistance in male genital tract secretions: implications for secondary transmission. J Infect Dis. 2007 Aug 01; 196(3):356-60. Smith DM, Wong JK, Shao H, Hightower GK, Mai SH, Moreno JM, Ignacio CC, Frost SD, Richman DD, Little SJ. PMID: 17597449.
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    181. Unprotected anal intercourse and substance use before and after HIV diagnosis among recently HIV-infected men who have sex with men. Sex Transm Dis. 2007 Jun; 34(6):401-7. Drumright LN, Strathdee SA, Little SJ, Araneta MR, Slymen DJ, Malcarne VL, Daar ES, Gorbach PM. PMID: 17091117.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    182. Recognition of a defined region within p24 gag by CD8+ T cells during primary human immunodeficiency virus type 1 infection in individuals expressing protective HLA class I alleles. J Virol. 2007 Jul; 81(14):7725-31. Streeck H, Lichterfeld M, Alter G, Meier A, Teigen N, Yassine-Diab B, Sidhu HK, Little S, Kelleher A, Routy JP, Rosenberg ES, Sekaly RP, Walker BD, Altfeld M. PMID: 17494064; PMCID: PMC1933382.
      View in: PubMed   Mentions: 79     Fields:    Translation:HumansCells
    183. Herpes simplex virus type 2 infection does not influence viral dynamics during early HIV-1 infection. J Infect Dis. 2007 May 01; 195(9):1270-7. Cachay ER, Frost SD, Richman DD, Smith DM, Little SJ. PMID: 17396995.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    184. Clinical utility of HIV standard genotyping among antiretroviral-naive individuals with unknown duration of infection. Clin Infect Dis. 2007 Feb 01; 44(3):456-8. Smith D, Moini N, Pesano R, Cachay E, Aiem H, Lie Y, Richman D, Little S. PMID: 17205459.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    185. Characteristics of recently HIV-infected men who use the Internet to find male sex partners and sexual practices with those partners. . 2006 Dec 15; 43(5):582-7. Smith DM, Drumright LN, Frost SD, Cheng WS, Espitia S, Daar ES, Little SJ, Gorbach PM. PMID: 17019370.
      View in: PubMed   Mentions: 8  Translation:Humans
    186. Unprotected anal intercourse and substance use among men who have sex with men with recent HIV infection. . 2006 Nov 01; 43(3):344-50. Drumright LN, Little SJ, Strathdee SA, Slymen DJ, Araneta MR, Malcarne VL, Daar ES, Gorbach PM. PMID: 16980913.
      View in: PubMed   Mentions: 48  Translation:Humans
    187. Greater CD4 T-cell gains after one year of antiretroviral therapy are associated with lower HIV-1 pol replication capacity. AIDS. 2006 Oct 24; 20(16):2123-5. Barbour JD, Hecht FM, Little SJ, Markowitz M, Daar ES, Kelleher AD, Routy JP, Campbell TB, Rosenberg ES, Segal MR, Weidler J, Grant RM. PMID: 17053362.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    188. Lack of neutralizing antibody response to HIV-1 predisposes to superinfection. Virology. 2006 Nov 10; 355(1):1-5. Smith DM, Strain MC, Frost SD, Pillai SK, Wong JK, Wrin T, Liu Y, Petropolous CJ, Daar ES, Little SJ, Richman DD. PMID: 16962152.
      View in: PubMed   Mentions: 52     Fields:    Translation:HumansCells
    189. A multicenter observational study of the potential benefits of initiating combination antiretroviral therapy during acute HIV infection. J Infect Dis. 2006 Sep 15; 194(6):725-33. Hecht FM, Wang L, Collier A, Little S, Markowitz M, Margolick J, Kilby JM, Daar E, Conway B, Holte S, AIEDRP Network. PMID: 16941337.
      View in: PubMed   Mentions: 69     Fields:    Translation:HumansCells
    190. Transmission behaviors of recently HIV-infected men who have sex with men. . 2006 May; 42(1):80-5. Gorbach PM, Drumright LN, Daar ES, Little SJ. PMID: 16763494.
      View in: PubMed   Mentions: 41  Translation:Humans
    191. Simian immunodeficiency virus engrafted with human immunodeficiency virus type 1 (HIV-1)-specific epitopes: replication, neutralization, and survey of HIV-1-positive plasma. J Virol. 2006 Mar; 80(6):3030-41. Yuste E, Sanford HB, Carmody J, Bixby J, Little S, Zwick MB, Greenough T, Burton DR, Richman DD, Desrosiers RC, Johnson WE. PMID: 16501112; PMCID: PMC1395451.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansAnimalsCells
    192. Neutralizing antibody responses drive the evolution of human immunodeficiency virus type 1 envelope during recent HIV infection. Proc Natl Acad Sci U S A. 2005 Dec 20; 102(51):18514-9. Frost SD, Wrin T, Smith DM, Kosakovsky Pond SL, Liu Y, Paxinos E, Chappey C, Galovich J, Beauchaine J, Petropoulos CJ, Little SJ, Richman DD. PMID: 16339909; PMCID: PMC1310509.
      View in: PubMed   Mentions: 185     Fields:    Translation:HumansCells
    193. HIV drug resistance acquired through superinfection. AIDS. 2005 Aug 12; 19(12):1251-6. Smith DM, Wong JK, Hightower GK, Ignacio CC, Koelsch KK, Petropoulos CJ, Richman DD, Little SJ. PMID: 16052079.
      View in: PubMed   Mentions: 39     Fields:    Translation:Humans
    194. HIV treatment decisions and transmitted drug resistance. Clin Infect Dis. 2005 Jul 15; 41(2):233-5. Little SJ, Smith DM. PMID: 15983921.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    195. HIV superinfection. J Infect Dis. 2005 Aug 01; 192(3):438-44. Smith DM, Richman DD, Little SJ. PMID: 15995957.
      View in: PubMed   Mentions: 71     Fields:    Translation:Humans
    196. Characterization of human immunodeficiency virus type 1 (HIV-1) envelope variation and neutralizing antibody responses during transmission of HIV-1 subtype B. J Virol. 2005 May; 79(10):6523-7. Frost SD, Liu Y, Pond SL, Chappey C, Wrin T, Petropoulos CJ, Little SJ, Richman DD. PMID: 15858036; PMCID: PMC1091710.
      View in: PubMed   Mentions: 103     Fields:    Translation:HumansCells
    197. Effect of treatment, during primary infection, on establishment and clearance of cellular reservoirs of HIV-1. J Infect Dis. 2005 May 01; 191(9):1410-8. Strain MC, Little SJ, Daar ES, Havlir DV, Gunthard HF, Lam RY, Daly OA, Nguyen J, Ignacio CC, Spina CA, Richman DD, Wong JK. PMID: 15809898.
      View in: PubMed   Mentions: 149     Fields:    Translation:HumansCells
    198. Human immunodeficiency virus type 1 clade B superinfection: evidence for differential immune containment of distinct clade B strains. J Virol. 2005 Jan; 79(2):860-8. Yang OO, Daar ES, Jamieson BD, Balamurugan A, Smith DM, Pitt JA, Petropoulos CJ, Richman DD, Little SJ, Brown AJ. PMID: 15613314; PMCID: PMC538553.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansCells
    199. HIV-specific cytotoxic T cells from long-term survivors select a unique T cell receptor. J Exp Med. 2004 Dec 20; 200(12):1547-57. Dong T, Stewart-Jones G, Chen N, Easterbrook P, Xu X, Papagno L, Appay V, Weekes M, Conlon C, Spina C, Little S, Screaton G, van der Merwe A, Richman DD, McMichael AJ, Jones EY, Rowland-Jones SL. PMID: 15596521; PMCID: PMC2212004.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansCells
    200. Incidence of HIV superinfection following primary infection. JAMA. 2004 Sep 08; 292(10):1177-8. Smith DM, Wong JK, Hightower GK, Ignacio CC, Koelsch KK, Daar ES, Richman DD, Little SJ. PMID: 15353529.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansCells
    201. The prostate as a reservoir for HIV-1. AIDS. 2004 Jul 23; 18(11):1600-2. Smith DM, Kingery JD, Wong JK, Ignacio CC, Richman DD, Little SJ. PMID: 15238781.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    202. Genetic basis of hypersusceptibility to protease inhibitors and low replicative capacity of human immunodeficiency virus type 1 strains in primary infection. J Virol. 2004 Mar; 78(5):2242-6. Leigh Brown AJ, Frost SD, Good B, Daar ES, Simon V, Markowitz M, Collier AC, Connick E, Conway B, Margolick JB, Routy JP, Corbeil J, Hellmann NS, Richman DD, Little SJ. PMID: 14963120; PMCID: PMC369210.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    203. Immune activation and CD8+ T-cell differentiation towards senescence in HIV-1 infection. PLoS Biol. 2004 Feb; 2(2):E20. Papagno L, Spina CA, Marchant A, Salio M, Rufer N, Little S, Dong T, Chesney G, Waters A, Easterbrook P, Dunbar PR, Shepherd D, Cerundolo V, Emery V, Griffiths P, Conlon C, McMichael AJ, Richman DD, Rowland-Jones SL, Appay V. PMID: 14966528; PMCID: PMC340937.
      View in: PubMed   Mentions: 170     Fields:    Translation:HumansCells
    204. HIV evolution and escape. Trans Am Clin Climatol Assoc. 2004; 115:289-303. Richman DD, Little SJ, Smith DM, Wrin T, Petropoulos C, Wong JK. PMID: 17060974; PMCID: PMC2263778.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    205. Polyclonal proliferation and apoptosis of CCR5+ T lymphocytes during primary human immunodeficiency virus type 1 infection: regulation by interleukin (IL)-2, IL-15, and Bcl-2. J Infect Dis. 2003 Jun 01; 187(11):1735-47. Zaunders JJ, Moutouh-de Parseval L, Kitada S, Reed JC, Rought S, Genini D, Leoni L, Kelleher A, Cooper DA, Smith DE, Grey P, Estaquier J, Little S, Richman DD, Corbeil J. PMID: 12751031.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    206. Clade B HIV-1 superinfection with wild-type virus after primary infection with drug-resistant clade B virus. AIDS. 2003 May 02; 17(7):F11-6. Koelsch KK, Smith DM, Little SJ, Ignacio CC, Macaranas TR, Brown AJ, Petropoulos CJ, Richman DD, Wong JK. PMID: 12700477.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansCells
    207. Rapid evolution of the neutralizing antibody response to HIV type 1 infection. Proc Natl Acad Sci U S A. 2003 Apr 01; 100(7):4144-9. Richman DD, Wrin T, Little SJ, Petropoulos CJ. PMID: 12644702; PMCID: PMC153062.
      View in: PubMed   Mentions: 596     Fields:    Translation:HumansCells
    208. Transmission fitness of drug-resistant human immunodeficiency virus and the prevalence of resistance in the antiretroviral-treated population. J Infect Dis. 2003 Feb 15; 187(4):683-6. Leigh Brown AJ, Frost SD, Mathews WC, Dawson K, Hellmann NS, Daar ES, Richman DD, Little SJ. PMID: 12599087.
      View in: PubMed   Mentions: 51     Fields:    Translation:HumansCells
    209. Antiretroviral-drug resistance among patients recently infected with HIV. N Engl J Med. 2002 Aug 08; 347(6):385-94. Little SJ, Holte S, Routy JP, Daar ES, Markowitz M, Collier AC, Koup RA, Mellors JW, Connick E, Conway B, Kilby M, Wang L, Whitcomb JM, Hellmann NS, Richman DD. PMID: 12167680.
      View in: PubMed   Mentions: 294     Fields:    Translation:HumansCells
    210. Memory CD8+ T cells vary in differentiation phenotype in different persistent virus infections. Nat Med. 2002 Apr; 8(4):379-85. Appay V, Dunbar PR, Callan M, Klenerman P, Gillespie GM, Papagno L, Ogg GS, King A, Lechner F, Spina CA, Little S, Havlir DV, Richman DD, Gruener N, Pape G, Waters A, Easterbrook P, Salio M, Cerundolo V, McMichael AJ, Rowland-Jones SL. PMID: 11927944.
      View in: PubMed   Mentions: 515     Fields:    Translation:HumansCells
    211. Dynamics of T cell responses in HIV infection. J Immunol. 2002 Apr 01; 168(7):3660-6. Appay V, Papagno L, Spina CA, Hansasuta P, King A, Jones L, Ogg GS, Little S, McMichael AJ, Richman DD, Rowland-Jones SL. PMID: 11907132.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansCells
    212. Transmission and prevalence of HIV resistance among treatment-naive subjects. Antivir Ther. 2000 Mar; 5(1):33-40. Little SJ. PMID: 10846591.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    213. Viral dynamics of acute HIV-1 infection. J Exp Med. 1999 Sep 20; 190(6):841-50. Little SJ, McLean AR, Spina CA, Richman DD, Havlir DV. PMID: 10499922; PMCID: PMC2195636.
      View in: PubMed   Mentions: 107     Fields:    Translation:HumansCells
    214. Reduced antiretroviral drug susceptibility among patients with primary HIV infection. JAMA. 1999 Sep 22-29; 282(12):1142-9. Little SJ, Daar ES, D'Aquila RT, Keiser PH, Connick E, Whitcomb JM, Hellmann NS, Petropoulos CJ, Sutton L, Pitt JA, Rosenberg ES, Koup RA, Walker BD, Richman DD. PMID: 10501117.
      View in: PubMed   Mentions: 56     Fields:    Translation:HumansCells
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