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Susan Little

Title(s)Professor In Residence, Medicine
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Collapse Research 
    Collapse Research Activities and Funding
    Risks, Benefits, and Stakeholder Perspectives of Molecular Epidemiology for HIV Prevention (HIV-ME)
    NIH R01MH124590Jul 8, 2020 - Apr 30, 2025
    Role: Principal Investigator
    Characterizing Privacy Perceptions and Risks in HIV Molecular Epidemiology
    NIH R21AI108351Jun 1, 2014 - May 31, 2017
    Role: Principal Investigator
    Efficacy of ART to Interrupt HIV Transmission Networks
    NIH R01MH100974May 12, 2014 - Feb 29, 2020
    Role: Principal Investigator
    Primary Infection Resource Consortium (PIRC)
    NIH R24AI106039Aug 20, 2013 - Jul 31, 2017
    Role: Principal Investigator
    Determinants of HIV Transmission
    NIH P01AI074621Mar 15, 2008 - Sep 26, 2012
    Role: Principal Investigator
    General Clinical Research Center
    NIH M01RR000827Jan 27, 1997 - Nov 30, 2010
    Role: Co-Investigator

    Collapse ORNG Applications 
    Collapse Clinical Trials
    Collapse Websites

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Interest, concerns, and attitudes among men who have sex with men and healthcare providers toward prophylactic use of doxycycline against Chlamydia trachomatis infections and syphilis. Sex Transm Dis. 2021 Feb 09. PMID: 33560092.
      View in: PubMed   Mentions:    Fields:    
    2. Integrase Strand Transfer Inhibitors Play the Main Role in Greater Weight Gain Among Men With Acute and Early HIV Infection. Open Forum Infect Dis. 2021 Jan; 8(1):ofaa619. Wu KS, Anderson C, Little SJ. PMID: 33511237.
      View in: PubMed   Mentions:
    3. HIV Screening in Emergency Departments: Linkage Works but What About Retention? Acad Emerg Med. 2020 Dec 12. Mathur K, Blumenthal J, Horton LE, Wagner GA, Martin TC, Lo M, Gianella S, Vilke GM, Coyne CJ, Little SJ, Hoenigl M. PMID: 33314418.
      View in: PubMed   Mentions: 1     Fields:    
    4. "[It] is now my responsibility to fulfill that wish:" Clinical and rapid autopsy staff members' experiences and perceptions of HIV reservoir research at the end of life. PLoS One. 2020; 15(11):e0242420. Perry KE, Taylor J, Patel H, Javadi SS, Mathur K, Kaytes A, Concha-Garcia S, Little S, Smith D, Gianella S, Dubé K. PMID: 33206710.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    5. Addressing Ethical Challenges in US-Based HIV Phylogenetic Research. J Infect Dis. 2020 Nov 13; 222(12):1997-2006. Dawson L, Benbow N, Fletcher FE, Kassaye S, Killelea A, Latham SR, Lee LM, Leitner T, Little SJ, Mehta SR, Martinez O, Minalga B, Poon A, Rennie S, Sugarman J, Sweeney P, Torian LV, Wertheim JO. PMID: 32525980.
      View in: PubMed   Mentions: 3     Fields:    
    6. Grindr Users Take More Risks, but Are More Open to Human Immunodeficiency Virus (HIV) Pre-exposure Prophylaxis: Could This Dating App Provide a Platform for HIV Prevention Outreach? Clin Infect Dis. 2020 Oct 23; 71(7):e135-e140. Hoenigl M, Little SJ, Grelotti D, Skaathun B, Wagner GA, Weibel N, Stockman JK, Smith DM. PMID: 31677383.
      View in: PubMed   Mentions: 3     Fields:    
    7. Bayesian reconstruction of transmission trees from genetic sequences and uncertain infection times. Stat Appl Genet Mol Biol. 2020 Oct 21. Montazeri H, Little S, Mozaffarilegha M, Beerenwinkel N, DeGruttola V. PMID: 33085643.
      View in: PubMed   Mentions:    Fields:    
    8. Dynamics and Dispersal of Local HIV Epidemics Within San Diego and Across The San Diego-Tijuana Border. Clin Infect Dis. 2020 Oct 20. Vrancken B, Mehta SR, Ávila-Ríos S, García-Morales C, Tapia-Trejo D, Reyes-Terán G, Navarro-Álvarez S, Little SJ, Hoenigl M, Pines HA, Patterson T, Strathdee SA, Smith DM, Dellicour S, Chaillon A. PMID: 33079188.
      View in: PubMed   Mentions:    Fields:    
    9. Switching to Tenofovir Alafenamide in Elvitegravir-Based Regimens: Pharmacokinetics and Antiviral Activity in Cerebrospinal Fluid. Clin Infect Dis. 2020 Aug 14; 71(4):982-988. Ma Q, Ocque AJ, Morse GD, Sanders C, Burgi A, Little SJ, Letendre SL. PMID: 31560741.
      View in: PubMed   Mentions:    Fields:    
    10. Rapid antiretroviral therapy among individuals with acute and early HIV. Clin Infect Dis. 2020 Aug 10. Martin TCS, Abrams M, Anderson C, Little SJ. PMID: 32777035.
      View in: PubMed   Mentions:    Fields:    
    11. Biometric Registration to an HIV Research Study may Deter Participation. AIDS Behav. 2020 Aug 07. Abrams MP, Torres FE, Little SJ. PMID: 32767155.
      View in: PubMed   Mentions:    Fields:    
    12. Perceptions of Next-of-Kin/Loved Ones About Last Gift Rapid Research Autopsy Study Enrolling People with HIV/AIDS at the End of Life: A Qualitative Interview Study. AIDS Res Hum Retroviruses. 2020 12; 36(12):1033-1046. Dubé K, Patel H, Concha-Garcia S, Perry KE, Mathur K, Javadi SS, Taylor J, Kaytes A, Brown B, Sauceda JA, Little S, Hendrickx S, Rawlings SA, Smith DM, Gianella S. PMID: 32449624.
      View in: PubMed   Mentions: 2     Fields:    
    13. "My Death Will Not [Be] in Vain": Testimonials from Last Gift Rapid Research Autopsy Study Participants Living with HIV at the End of Life. AIDS Res Hum Retroviruses. 2020 Dec; 36(12):1071-1082. Perry KE, Dubé K, Concha-Garcia S, Patel H, Kaytes A, Taylor J, Javadi SS, Mathur K, Lo M, Brown B, Sauceda JA, Wohl DA, Little S, Hendrickx S, Rawlings SA, Smith DM, Gianella S. PMID: 32449625.
      View in: PubMed   Mentions: 2     Fields:    
    14. Phylogenetic Cluster Analysis: Persons with Undiagnosed Infection Drive HIV Transmission in a Population with High Levels of Virologic Suppression. Clin Infect Dis. 2020 Apr 08. Mehta SR, Little SJ. PMID: 32266376.
      View in: PubMed   Mentions:    Fields:    
    15. Salvage Antiretroviral Therapy: Time for "DeNUKElearization"? J Infect Dis. 2020 Apr 07; 221(9):1390-1393. Hoenigl M, Little SJ. PMID: 31136663.
      View in: PubMed   Mentions: 1     Fields:    
    16. Genetic Network Analysis to Assess the Risk of Human Immunodeficiency Virus Transmission Among Men Who Have Sex With Men Seeking Partners on the Internet. Clin Infect Dis. 2020 02 14; 70(5):925-932. Martin TCS, Chaillon A, Graves SK, Lin T, Gianella S, Smith DM, Little SJ, Hoenigl M. PMID: 30953067.
      View in: PubMed   Mentions: 3     Fields:    
    17. Optimizing Screening for HIV. Open Forum Infect Dis. 2020 Feb; 7(2):ofaa024. Chaillon A, Hoenigl M, Freitas L, Feldman H, Tilghman W, Wang L, Smith D, Little S, Mehta SR. PMID: 32055638.
      View in: PubMed   Mentions:
    18. Canine Leishmaniasis Control in the Context of One Health. Emerg Infect Dis. 2019 12; 25(12):1-4. Dantas-Torres F, Miró G, Baneth G, Bourdeau P, Breitschwerdt E, Capelli G, Cardoso L, Day MJ, Dobler G, Ferrer L, Irwin P, Jongejan F, Kempf VAJ, Kohn B, Lappin M, Little S, Madder M, Maggi R, Maia C, Marcondes M, Naucke T, Oliva G, Pennisi MG, Penzhorn BL, Peregrine A, Pfeffer M, Roura X, Sainz A, Shin S, Solano-Gallego L, Straubinger RK, Tasker S, Traub R, Wright I, Bowman DD, Gradoni L, Otranto D. PMID: 31742505.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    19. I wanted it as soon as possible: a qualitative exploration of reactions to access to same-day ART start among participants in San Diego's ART-NET project. AIDS Care. 2020 09; 32(9):1191-1197. Amico KR, Miller J, Schairer C, Gianella S, Little SJ, Hoenigl M. PMID: 31713432.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    20. Universal HIV and Birth Cohort HCV Screening in San Diego Emergency Departments. Sci Rep. 2019 10 09; 9(1):14479. Hoenigl M, Mathur K, Blumenthal J, Brennan J, Zuazo M, McCauley M, Horton LE, Wagner GA, Reed SL, Vilke GM, Coyne CJ, Little SJ. PMID: 31597939.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansPHPublic Health
    21. Meta-analysis of the Cepheid Xpert® CT/NG assay for extragenital detection of Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) infections. Sex Health. 2019 08; 16(4):314-319. Bristow CC, Morris SR, Little SJ, Mehta SR, Klausner JD. PMID: 31296280.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    22. Trust and Expectations of Researchers and Public Health Departments for the Use of HIV Molecular Epidemiology. AJOB Empir Bioeth. 2019 Jul-Sep; 10(3):201-213. Schairer CE, Mehta SR, Vinterbo SA, Hoenigl M, Kalichman M, Little SJ. PMID: 31050604.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    23. Ethical issues in HIV phylogenetics and molecular epidemiology. Curr Opin HIV AIDS. 2019 05; 14(3):221-226. Mehta SR, Schairer C, Little S. PMID: 30946143.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCellsPHPublic Health
    24. Primary Incidence of Hepatitis C Virus Infection Among HIV-Infected Men Who Have Sex With Men in San Diego, 2000-2015. Open Forum Infect Dis. 2019 Apr; 6(4):ofz160. Chaillon A, Sun X, Cachay ER, Looney D, Wyles D, Garfein RS, Martin TCS, Jain S, Mehta SR, Smith DM, Little SJ, Martin NK. PMID: 31041355.
      View in: PubMed   Mentions:
    25. Herd Immunity Likely Protected the Men Who Have Sex With Men in the Recent Hepatitis A Outbreak in San Diego, California. Clin Infect Dis. 2019 03 19; 68(7):1228-1230. Smith D, Huynh C, Moore AJ, Frick A, Anderson C, Porrachia M, Scott B, Stous S, Schooley R, Little S, Santos AT. PMID: 30052941.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCellsPHPublic Health
    26. Attitudes and Preferences Regarding the Use of Rapid Self-Testing for Sexually Transmitted Infections and HIV in San Diego Area Men Who Have Sex With Men. Open Forum Infect Dis. 2019 Mar; 6(3):ofz043. Cushman TA, Graves SK, Little SJ. PMID: 30906798.
      View in: PubMed   Mentions:
    27. The inhibitor apoptosis protein antagonist Debio 1143 Is an attractive HIV-1 latency reversal candidate. PLoS One. 2019; 14(2):e0211746. Bobardt M, Kuo J, Chatterji U, Chanda S, Little SJ, Wiedemann N, Vuagniaux G, Gallay PA. PMID: 30716099.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    28. The Control of HIV After Antiretroviral Medication Pause (CHAMP) Study: Posttreatment Controllers Identified From 14 Clinical Studies. J Infect Dis. 2018 11 05; 218(12):1954-1963. Namazi G, Fajnzylber JM, Aga E, Bosch RJ, Acosta EP, Sharaf R, Hartogensis W, Jacobson JM, Connick E, Volberding P, Skiest D, Margolis D, Sneller MC, Little SJ, Gianella S, Smith DM, Kuritzkes DR, Gulick RM, Mellors JW, Mehraj V, Gandhi RT, Mitsuyasu R, Schooley RT, Henry K, Tebas P, Deeks SG, Chun TW, Collier AC, Routy JP, Hecht FM, Walker BD, Li JZ. PMID: 30085241.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansCells
    29. Ethical considerations for HIV cure-related research at the end of life. BMC Med Ethics. 2018 10 20; 19(1):83. Dubé K, Gianella S, Concha-Garcia S, Little SJ, Kaytes A, Taylor J, Mathur K, Javadi S, Nathan A, Patel H, Luter S, Philpott-Jones S, Brown B, Smith D. PMID: 30342507.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    30. Antigen-specific antibody Fc glycosylation enhances humoral immunity via the recruitment of complement. Sci Immunol. 2018 08 17; 3(26). Lofano G, Gorman MJ, Yousif AS, Yu WH, Fox JM, Dugast AS, Ackerman ME, Suscovich TJ, Weiner J, Barouch D, Streeck H, Little S, Smith D, Richman D, Lauffenburger D, Walker BD, Diamond MS, Alter G. PMID: 30120121.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    31. A Simple Symptom Score for Acute Human Immunodeficiency Virus Infection in a San Diego Community-Based Screening Program. Clin Infect Dis. 2018 06 18; 67(1):105-111. Lin TC, Gianella S, Tenenbaum T, Little SJ, Hoenigl M. PMID: 29293891.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCellsPHPublic Health
    32. Temporal variation in HIV-specific IgG subclass antibodies during acute infection differentiates spontaneous controllers from chronic progressors. AIDS. 2018 02 20; 32(4):443-450. Sadanand S, Das J, Chung AW, Schoen MK, Lane S, Suscovich TJ, Streeck H, Smith DM, Little SJ, Lauffenburger DA, Richman DD, Alter G. PMID: 29239894.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    33. Size, Composition, and Evolution of HIV DNA Populations during Early Antiretroviral Therapy and Intensification with Maraviroc. J Virol. 2018 02 01; 92(3). Chaillon A, Gianella S, Lada SM, Perez-Santiago J, Jordan P, Ignacio C, Karris M, Richman DD, Mehta SR, Little SJ, Wertheim JO, Smith DM. PMID: 29142136.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    34. Infection Staging and Incidence Surveillance Applications of High Dynamic Range Diagnostic Immuno-Assay Platforms. . 2017 12 15; 76(5):547-555. Grebe E, Welte A, Hall J, Keating SM, Facente SN, Marson K, Martin JN, Little SJ, Price MA, Kallas EG, Busch MP, Pilcher CD, Murphy G. PMID: 28914669.
      View in: PubMed   Mentions:
    35. Perceptions of molecular epidemiology studies of HIV among stakeholders. J Public Health Res. 2017 Dec 13; 6(3):992. Schairer C, Mehta SR, Vinterbo SA, Hoenigl M, Kalichman M, Little S. PMID: 29291190.
      View in: PubMed   Mentions:
    36. No Substantial Evidence for Sexual Transmission of Minority HIV Drug Resistance Mutations in Men Who Have Sex with Men. J Virol. 2017 11 01; 91(21). Chaillon A, Nakazawa M, Wertheim JO, Little SJ, Smith DM, Mehta SR, Gianella S. PMID: 28794047.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    37. Sexual Partner Concurrency Among Partners Reported by MSM with Recent HIV Infection. AIDS Behav. 2017 Oct; 21(10):3026-3034. Pines HA, Karris MY, Little SJ. PMID: 28702851.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    38. Intrasubtype B HIV-1 Superinfection Correlates with Delayed Neutralizing Antibody Response. J Virol. 2017 09 01; 91(17). Wagner GA, Landais E, Caballero G, Phung P, Kosakovsky Pond SL, Poignard P, Richman DD, Little SJ, Smith DM. PMID: 28615205.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    39. Identification and characterization of Nanobodies targeting the EphA4 receptor. J Biol Chem. 2017 07 07; 292(27):11452-11465. Schoonaert L, Rué L, Roucourt B, Timmers M, Little S, Chávez-Gutiérrez L, Dewilde M, Joyce P, Curnock A, Weber P, Haustraete J, Hassanzadeh-Ghassabeh G, De Strooper B, Van Den Bosch L, Van Damme P, Lemmens R, Robberecht W. PMID: 28526745.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    40. Increased HIV-1 superinfection risk in carriers of specific human leukocyte antigen alleles. AIDS. 2017 05 15; 31(8):1149-1158. Vesa J, Chaillon A, Wagner GA, Anderson CM, Richman DD, Smith DM, Little SJ. PMID: 28244954.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    41. Assessing the Performance of 3 Human Immunodeficiency Virus Incidence Risk Scores in a Cohort of Black and White Men Who Have Sex With Men in the South. Sex Transm Dis. 2017 05; 44(5):297-302. Jones J, Hoenigl M, Siegler AJ, Sullivan PS, Little S, Rosenberg E. PMID: 28407646.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansPHPublic Health
    42. Brief Report: Changes in Levels of Inflammation After Antiretroviral Treatment During Early HIV Infection in AIDS Clinical Trials Group Study A5217. . 2017 05 01; 75(1):137-141. Macatangay BJ, Yang M, Sun X, Morton J, De Gruttola V, Little S, Hogan C, Rinaldo CR. PMID: 28198712.
      View in: PubMed   Mentions:
    43. Evaluation of the Predictive Potential of the Short Acute Retroviral Syndrome Severity Score for HIV-1 Disease Progression in Individuals With Acute HIV Infection. . 2017 04 01; 74(4):e114-e117. Hoenigl M, Braun DL, Kouyos R, Günthard HF, Little SJ. PMID: 28225720.
      View in: PubMed   Mentions:
    44. Longitudinal Viral Dynamics in Semen During Early HIV Infection. Clin Infect Dis. 2017 02 15; 64(4):428-434. Morris SR, Zhao M, Smith DM, Vargas MV, Little SJ, Gianella S. PMID: 28174909.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    45. Risk profile and HIV testing outcomes of women undergoing community-based testing in San Diego 2008-2014. Sci Rep. 2017 02 06; 7:42183. Graves SK, Little SJ, Hoenigl M. PMID: 28165056.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansPHPublic Health
    46. Evaluation of opt-out inpatient HIV screening at an urban teaching hospital. AIDS Care. 2017 08; 29(8):1014-1018. Osorio G, Hoenigl M, Quartarolo J, Barger K, Morris SR, Reed SL, Lee J, Little SJ. PMID: 28114789.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansPHPublic Health
    47. Partner services in adults with acute and early HIV infection. AIDS. 2017 01 14; 31(2):287-293. Green N, Hoenigl M, Chaillon A, Anderson CM, Kosakovsky Pond SL, Smith DM, Little SJ. PMID: 27831950.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansPHPublic Health
    48. Early Antiretroviral Therapy Is Associated with Lower HIV DNA Molecular Diversity and Lower Inflammation in Cerebrospinal Fluid but Does Not Prevent the Establishment of Compartmentalized HIV DNA Populations. PLoS Pathog. 2017 01; 13(1):e1006112. Oliveira MF, Chaillon A, Nakazawa M, Vargas M, Letendre SL, Strain MC, Ellis RJ, Morris S, Little SJ, Smith DM, Gianella S. PMID: 28046096.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCellsPHPublic Health
    49. Can research at the end of life be a useful tool to advance HIV cure? AIDS. 2017 01 02; 31(1):1-4. Gianella S, Taylor J, Brown TR, Kaytes A, Achim CL, Moore DJ, Little SJ, Ellis RJ, Smith DM. PMID: 27755112.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    50. Performance of the Bio-Rad Geenius HIV1/2 Supplemental Assay in Detecting "Recent" HIV Infection and Calculating Population Incidence. . 2016 Dec 15; 73(5):581-588. Keating SM, Kassanjee R, Lebedeva M, Facente SN, MacArthur JC, Grebe E, Murphy G, Welte A, Martin JN, Little S, Price MA, Kallas EG, Busch MP, Pilcher CD. PMID: 27509247.
      View in: PubMed   Mentions:
    51. Treatment of Acute HIV Infection and the Potential Role of Acutely HIV-Infected Persons in Cure Studies. Top Antivir Med. 2016 Dec-2017 Jan; 23(5):156-60. Little SJ. PMID: 27398768.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    52. Concurrency and HIV transmission network characteristics among MSM with recent HIV infection. AIDS. 2016 11 28; 30(18):2875-2883. Pines HA, Wertheim JO, Liu L, Garfein RS, Little SJ, Karris MY. PMID: 27662550.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    53. A randomized controlled clinical trial on the impact of CCR5 blockade with maraviroc in early infection on T-cell dynamics. Medicine (Baltimore). 2016 Nov; 95(44):e5315. Karris MY, Umlauf A, Vaida F, Richman D, Little S, Smith D. PMID: 27858912.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    54. Viral load criteria and threshold optimization to improve HIV incidence assay characteristics. AIDS. 2016 09 24; 30(15):2361-71. Kassanjee R, Pilcher CD, Busch MP, Murphy G, Facente SN, Keating SM, Mckinney E, Marson K, Price MA, Martin JN, Little SJ, Hecht FM, Kallas EG, Welte A. PMID: 27454561.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    55. Asymptomatic CMV Replication During Early Human Immunodeficiency Virus (HIV) Infection Is Associated With Lower CD4/CD8 Ratio During HIV Treatment. Clin Infect Dis. 2016 Dec 01; 63(11):1517-1524. Smith DM, Nakazawa M, Freeman ML, Anderson CM, Oliveira MF, Little SJ, Gianella S. PMID: 27601222.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    56. Rapid HIV Viral Load Suppression in those Initiating Antiretroviral Therapy at First Visit after HIV Diagnosis. Sci Rep. 2016 09 06; 6:32947. Hoenigl M, Chaillon A, Moore DJ, Morris SR, Mehta SR, Gianella S, Amico KR, Little SJ. PMID: 27597312.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    57. How can we detect HIV during the acute or primary stage of infection? Expert Rev Mol Diagn. 2016 10; 16(10):1049-1051. Hoenigl M, Little SJ. PMID: 27541993.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    58. Screening for acute HIV infection in community-based settings: Cost-effectiveness and impact on transmissions. J Infect. 2016 11; 73(5):476-484. Hoenigl M, Chaillon A, Mehta SR, Smith DM, Graff-Zivin J, Little SJ. PMID: 27521468.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    59. A practical online tool to estimate antiretroviral coverage for HIV infected and susceptible populations needed to reduce local HIV epidemics. Sci Rep. 2016 06 24; 6:28707. Chaillon A, Hoenigl M, Mehta SR, Weibel N, Little SJ, Smith DM. PMID: 27337983.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansPHPublic Health
    60. Characterizing the multiplicity of HIV founder variants during sexual transmission among MSM. Virus Evol. 2016 Jan; 2(1):vew012. Chaillon A, Gianella S, Little SJ, Caballero G, Barin F, Kosakovsky Pond S, Richman DD, Smith DM, Mehta SR. PMID: 30186625.
      View in: PubMed   Mentions:
    61. HIV Infection Rates and Risk Behavior among Young Men undergoing community-based Testing in San Diego. Sci Rep. 2016 05 16; 6:25927. Hoenigl M, Chaillon A, Morris SR, Little SJ. PMID: 27181715.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansPHPublic Health
    62. Using HIV Sequence and Epidemiologic Data to Assess the Effect of Self-referral Testing for Acute HIV Infection on Incident Diagnoses in San Diego, California. Clin Infect Dis. 2016 07 01; 63(1):101-107. Mehta SR, Murrell B, Anderson CM, Kosakovsky Pond SL, Wertheim JO, Young JA, Freitas L, Richman DD, Mathews WC, Scheffler K, Little SJ, Smith DM. PMID: 27174704.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCellsPHPublic Health
    63. CD4/CD8 Cell Ratio in Acute HIV Infection and the Impact of Early Antiretroviral Therapy. Clin Infect Dis. 2016 08 01; 63(3):425-6. Hoenigl M, Chaillon A, Little SJ. PMID: 27143670.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    64. Clear Links Between Starting Methamphetamine and Increasing Sexual Risk Behavior: A Cohort Study Among Men Who Have Sex With Men. . 2016 Apr 15; 71(5):551-7. Hoenigl M, Chaillon A, Moore DJ, Morris SR, Smith DM, Little SJ. PMID: 26536321.
      View in: PubMed   Mentions:
    65. Replication of Human Herpesviruses Is Associated with Higher HIV DNA Levels during Antiretroviral Therapy Started at Early Phases of HIV Infection. J Virol. 2016 Apr; 90(8):3944-3952. Gianella S, Anderson CM, Var SR, Oliveira MF, Lada SM, Vargas MV, Massanella M, Little SJ, Richman DD, Strain MC, Pérez-Santiago J, Smith DM. PMID: 26842469.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCells
    66. Characterization of HIV Transmission in South-East Austria. PLoS One. 2016; 11(3):e0151478. Hoenigl M, Chaillon A, Kessler HH, Haas B, Stelzl E, Weninger K, Little SJ, Mehta SR. PMID: 26967154.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    67. Neurobehavioral Disturbances During Acute and Early HIV Infection. Cogn Behav Neurol. 2016 Mar; 29(1):1-10. Kamat R, Doyle KL, Iudicello JE, Morgan EE, Morris S, Smith DM, Little SJ, Grant I, Woods SP. PMID: 27008244.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    68. Signs or Symptoms of Acute HIV Infection in a Cohort Undergoing Community-Based Screening. Emerg Infect Dis. 2016 Mar; 22(3):532-4. Hoenigl M, Green N, Camacho M, Gianella S, Mehta SR, Smith DM, Little SJ. PMID: 26890854.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCellsPHPublic Health
    69. Prevalence of Transmitted HIV Drug Resistance Among Recently Infected Persons in San Diego, CA 1996-2013. . 2016 Feb 01; 71(2):228-36. Panichsillapakit T, Smith DM, Wertheim JO, Richman DD, Little SJ, Mehta SR. PMID: 26413846.
      View in: PubMed   Mentions:
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    77. Methamphetamine Use in HIV-infected Individuals Affects T-cell Function and Viral Outcome during Suppressive Antiretroviral Therapy. Sci Rep. 2015 Aug 24; 5:13179. Massanella M, Gianella S, Schrier R, Dan JM, Pérez-Santiago J, Oliveira MF, Richman DD, Little SJ, Benson CA, Daar ES, Dube MP, Haubrich RH, Smith DM, Morris SR. PMID: 26299251.
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    79. Seminal Shedding of CMV and HIV Transmission among Men Who Have Sex with Men. Int J Environ Res Public Health. 2015 Jul 07; 12(7):7585-92. Gianella S, Scheffler K, Mehta SR, Little SJ, Freitas L, Morris SR, Smith DM. PMID: 26198239.
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    84. Individualized diagnosis interventions can add significant effectiveness in reducing human immunodeficiency virus incidence among men who have sex with men: insights from Southern California. Ann Epidemiol. 2015 Jan; 25(1):1-6. Khanna A, Goodreau SM, Wohlfeiler D, Daar E, Little S, Gorbach PM. PMID: 25453725.
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    157. CCL3L1-CCR5 genotype influences durability of immune recovery during antiretroviral therapy of HIV-1-infected individuals. Nat Med. 2008 Apr; 14(4):413-20. Ahuja SK, Kulkarni H, Catano G, Agan BK, Camargo JF, He W, O'Connell RJ, Marconi VC, Delmar J, Eron J, Clark RA, Frost S, Martin J, Ahuja SS, Deeks SG, Little S, Richman D, Hecht FM, Dolan MJ. PMID: 18376407.
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    158. Persistence of transmitted drug resistance among subjects with primary human immunodeficiency virus infection. J Virol. 2008 Jun; 82(11):5510-8. Little SJ, Frost SD, Wong JK, Smith DM, Pond SL, Ignacio CC, Parkin NT, Petropoulos CJ, Richman DD. PMID: 18353964.
      View in: PubMed   Mentions: 98     Fields:    Translation:HumansCells
    159. Dynamics of total, linear nonintegrated, and integrated HIV-1 DNA in vivo and in vitro. J Infect Dis. 2008 Feb 01; 197(3):411-9. Koelsch KK, Liu L, Haubrich R, May S, Havlir D, Günthard HF, Ignacio CC, Campos-Soto P, Little SJ, Shafer R, Robbins GK, D'Aquila RT, Kawano Y, Young K, Dao P, Spina CA, Richman DD, Wong JK. PMID: 18248304.
      View in: PubMed   Mentions: 76     Fields:    Translation:HumansCells
    160. Treatment of acute HIV-1 infection: are we getting there? Curr Opin HIV AIDS. 2008 Jan; 3(1):67-74. Cellerai C, Little SJ, Loes SK. PMID: 19372946.
      View in: PubMed   Mentions: 4     Fields:    
    161. Associations between substance use, erectile dysfunction medication and recent HIV infection among men who have sex with men. AIDS Behav. 2009 Apr; 13(2):328-36. Drumright LN, Gorbach PM, Little SJ, Strathdee SA. PMID: 18064558.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    162. Application of multicomponent reactions to antimalarial drug discovery. Part 3: discovery of aminoxazole 4-aminoquinolines with potent antiplasmodial activity in vitro. Bioorg Med Chem Lett. 2007 Sep 01; 17(17):4733-6. Musonda CC, Little S, Yardley V, Chibale K. PMID: 17644333.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    163. Long-term persistence of transmitted HIV drug resistance in male genital tract secretions: implications for secondary transmission. J Infect Dis. 2007 Aug 01; 196(3):356-60. Smith DM, Wong JK, Shao H, Hightower GK, Mai SH, Moreno JM, Ignacio CC, Frost SD, Richman DD, Little SJ. PMID: 17597449.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansCells
    164. Unprotected anal intercourse and substance use before and after HIV diagnosis among recently HIV-infected men who have sex with men. Sex Transm Dis. 2007 Jun; 34(6):401-7. Drumright LN, Strathdee SA, Little SJ, Araneta MR, Slymen DJ, Malcarne VL, Daar ES, Gorbach PM. PMID: 17091117.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    165. Recognition of a defined region within p24 gag by CD8+ T cells during primary human immunodeficiency virus type 1 infection in individuals expressing protective HLA class I alleles. J Virol. 2007 Jul; 81(14):7725-31. Streeck H, Lichterfeld M, Alter G, Meier A, Teigen N, Yassine-Diab B, Sidhu HK, Little S, Kelleher A, Routy JP, Rosenberg ES, Sekaly RP, Walker BD, Altfeld M. PMID: 17494064.
      View in: PubMed   Mentions: 79     Fields:    Translation:HumansCells
    166. Herpes simplex virus type 2 infection does not influence viral dynamics during early HIV-1 infection. J Infect Dis. 2007 May 01; 195(9):1270-7. Cachay ER, Frost SD, Richman DD, Smith DM, Little SJ. PMID: 17396995.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    167. Clinical utility of HIV standard genotyping among antiretroviral-naive individuals with unknown duration of infection. Clin Infect Dis. 2007 Feb 01; 44(3):456-8. Smith D, Moini N, Pesano R, Cachay E, Aiem H, Lie Y, Richman D, Little S. PMID: 17205459.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    168. Characteristics of recently HIV-infected men who use the Internet to find male sex partners and sexual practices with those partners. . 2006 Dec 15; 43(5):582-7. Smith DM, Drumright LN, Frost SD, Cheng WS, Espitia S, Daar ES, Little SJ, Gorbach PM. PMID: 17019370.
      View in: PubMed   Mentions:
    169. Unprotected anal intercourse and substance use among men who have sex with men with recent HIV infection. . 2006 Nov 01; 43(3):344-50. Drumright LN, Little SJ, Strathdee SA, Slymen DJ, Araneta MR, Malcarne VL, Daar ES, Gorbach PM. PMID: 16980913.
      View in: PubMed   Mentions:
    170. Greater CD4 T-cell gains after one year of antiretroviral therapy are associated with lower HIV-1 pol replication capacity. AIDS. 2006 Oct 24; 20(16):2123-5. Barbour JD, Hecht FM, Little SJ, Markowitz M, Daar ES, Kelleher AD, Routy JP, Campbell TB, Rosenberg ES, Segal MR, Weidler J, Grant RM. PMID: 17053362.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    171. Lack of neutralizing antibody response to HIV-1 predisposes to superinfection. Virology. 2006 Nov 10; 355(1):1-5. Smith DM, Strain MC, Frost SD, Pillai SK, Wong JK, Wrin T, Liu Y, Petropolous CJ, Daar ES, Little SJ, Richman DD. PMID: 16962152.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansCells
    172. A multicenter observational study of the potential benefits of initiating combination antiretroviral therapy during acute HIV infection. J Infect Dis. 2006 Sep 15; 194(6):725-33. Hecht FM, Wang L, Collier A, Little S, Markowitz M, Margolick J, Kilby JM, Daar E, Conway B, Holte S. PMID: 16941337.
      View in: PubMed   Mentions: 68     Fields:    Translation:HumansCells
    173. Transmission behaviors of recently HIV-infected men who have sex with men. . 2006 May; 42(1):80-5. Gorbach PM, Drumright LN, Daar ES, Little SJ. PMID: 16763494.
      View in: PubMed   Mentions:
    174. Simian immunodeficiency virus engrafted with human immunodeficiency virus type 1 (HIV-1)-specific epitopes: replication, neutralization, and survey of HIV-1-positive plasma. J Virol. 2006 Mar; 80(6):3030-41. Yuste E, Sanford HB, Carmody J, Bixby J, Little S, Zwick MB, Greenough T, Burton DR, Richman DD, Desrosiers RC, Johnson WE. PMID: 16501112.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansAnimalsCells
    175. Neutralizing antibody responses drive the evolution of human immunodeficiency virus type 1 envelope during recent HIV infection. Proc Natl Acad Sci U S A. 2005 Dec 20; 102(51):18514-9. Frost SD, Wrin T, Smith DM, Kosakovsky Pond SL, Liu Y, Paxinos E, Chappey C, Galovich J, Beauchaine J, Petropoulos CJ, Little SJ, Richman DD. PMID: 16339909.
      View in: PubMed   Mentions: 180     Fields:    Translation:HumansCells
    176. HIV drug resistance acquired through superinfection. AIDS. 2005 Aug 12; 19(12):1251-6. Smith DM, Wong JK, Hightower GK, Ignacio CC, Koelsch KK, Petropoulos CJ, Richman DD, Little SJ. PMID: 16052079.
      View in: PubMed   Mentions: 36     Fields:    Translation:Humans
    177. HIV treatment decisions and transmitted drug resistance. Clin Infect Dis. 2005 Jul 15; 41(2):233-5. Little SJ, Smith DM. PMID: 15983921.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    178. HIV superinfection. J Infect Dis. 2005 Aug 01; 192(3):438-44. Smith DM, Richman DD, Little SJ. PMID: 15995957.
      View in: PubMed   Mentions: 67     Fields:    Translation:Humans
    179. Characterization of human immunodeficiency virus type 1 (HIV-1) envelope variation and neutralizing antibody responses during transmission of HIV-1 subtype B. J Virol. 2005 May; 79(10):6523-7. Frost SD, Liu Y, Pond SL, Chappey C, Wrin T, Petropoulos CJ, Little SJ, Richman DD. PMID: 15858036.
      View in: PubMed   Mentions: 98     Fields:    Translation:HumansCells
    180. Effect of treatment, during primary infection, on establishment and clearance of cellular reservoirs of HIV-1. J Infect Dis. 2005 May 01; 191(9):1410-8. Strain MC, Little SJ, Daar ES, Havlir DV, Gunthard HF, Lam RY, Daly OA, Nguyen J, Ignacio CC, Spina CA, Richman DD, Wong JK. PMID: 15809898.
      View in: PubMed   Mentions: 137     Fields:    Translation:HumansCells
    181. Human immunodeficiency virus type 1 clade B superinfection: evidence for differential immune containment of distinct clade B strains. J Virol. 2005 Jan; 79(2):860-8. Yang OO, Daar ES, Jamieson BD, Balamurugan A, Smith DM, Pitt JA, Petropoulos CJ, Richman DD, Little SJ, Brown AJ. PMID: 15613314.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansCells
    182. HIV-specific cytotoxic T cells from long-term survivors select a unique T cell receptor. J Exp Med. 2004 Dec 20; 200(12):1547-57. Dong T, Stewart-Jones G, Chen N, Easterbrook P, Xu X, Papagno L, Appay V, Weekes M, Conlon C, Spina C, Little S, Screaton G, van der Merwe A, Richman DD, McMichael AJ, Jones EY, Rowland-Jones SL. PMID: 15596521.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansCells
    183. Incidence of HIV superinfection following primary infection. JAMA. 2004 Sep 08; 292(10):1177-8. Smith DM, Wong JK, Hightower GK, Ignacio CC, Koelsch KK, Daar ES, Richman DD, Little SJ. PMID: 15353529.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansCells
    184. The prostate as a reservoir for HIV-1. AIDS. 2004 Jul 23; 18(11):1600-2. Smith DM, Kingery JD, Wong JK, Ignacio CC, Richman DD, Little SJ. PMID: 15238781.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    185. Genetic basis of hypersusceptibility to protease inhibitors and low replicative capacity of human immunodeficiency virus type 1 strains in primary infection. J Virol. 2004 Mar; 78(5):2242-6. Leigh Brown AJ, Frost SD, Good B, Daar ES, Simon V, Markowitz M, Collier AC, Connick E, Conway B, Margolick JB, Routy JP, Corbeil J, Hellmann NS, Richman DD, Little SJ. PMID: 14963120.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    186. Immune activation and CD8+ T-cell differentiation towards senescence in HIV-1 infection. PLoS Biol. 2004 Feb; 2(2):E20. Papagno L, Spina CA, Marchant A, Salio M, Rufer N, Little S, Dong T, Chesney G, Waters A, Easterbrook P, Dunbar PR, Shepherd D, Cerundolo V, Emery V, Griffiths P, Conlon C, McMichael AJ, Richman DD, Rowland-Jones SL, Appay V. PMID: 14966528.
      View in: PubMed   Mentions: 158     Fields:    Translation:HumansCells
    187. HIV evolution and escape. Trans Am Clin Climatol Assoc. 2004; 115:289-303. Richman DD, Little SJ, Smith DM, Wrin T, Petropoulos C, Wong JK. PMID: 17060974.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    188. Polyclonal proliferation and apoptosis of CCR5+ T lymphocytes during primary human immunodeficiency virus type 1 infection: regulation by interleukin (IL)-2, IL-15, and Bcl-2. J Infect Dis. 2003 Jun 01; 187(11):1735-47. Zaunders JJ, Moutouh-de Parseval L, Kitada S, Reed JC, Rought S, Genini D, Leoni L, Kelleher A, Cooper DA, Smith DE, Grey P, Estaquier J, Little S, Richman DD, Corbeil J. PMID: 12751031.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    189. Clade B HIV-1 superinfection with wild-type virus after primary infection with drug-resistant clade B virus. AIDS. 2003 May 02; 17(7):F11-6. Koelsch KK, Smith DM, Little SJ, Ignacio CC, Macaranas TR, Brown AJ, Petropoulos CJ, Richman DD, Wong JK. PMID: 12700477.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansCells
    190. Rapid evolution of the neutralizing antibody response to HIV type 1 infection. Proc Natl Acad Sci U S A. 2003 Apr 01; 100(7):4144-9. Richman DD, Wrin T, Little SJ, Petropoulos CJ. PMID: 12644702.
      View in: PubMed   Mentions: 563     Fields:    Translation:HumansCells
    191. Transmission fitness of drug-resistant human immunodeficiency virus and the prevalence of resistance in the antiretroviral-treated population. J Infect Dis. 2003 Feb 15; 187(4):683-6. Leigh Brown AJ, Frost SD, Mathews WC, Dawson K, Hellmann NS, Daar ES, Richman DD, Little SJ. PMID: 12599087.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansCells
    192. Antiretroviral-drug resistance among patients recently infected with HIV. N Engl J Med. 2002 Aug 08; 347(6):385-94. Little SJ, Holte S, Routy JP, Daar ES, Markowitz M, Collier AC, Koup RA, Mellors JW, Connick E, Conway B, Kilby M, Wang L, Whitcomb JM, Hellmann NS, Richman DD. PMID: 12167680.
      View in: PubMed   Mentions: 284     Fields:    Translation:HumansCells
    193. Memory CD8+ T cells vary in differentiation phenotype in different persistent virus infections. Nat Med. 2002 Apr; 8(4):379-85. Appay V, Dunbar PR, Callan M, Klenerman P, Gillespie GM, Papagno L, Ogg GS, King A, Lechner F, Spina CA, Little S, Havlir DV, Richman DD, Gruener N, Pape G, Waters A, Easterbrook P, Salio M, Cerundolo V, McMichael AJ, Rowland-Jones SL. PMID: 11927944.
      View in: PubMed   Mentions: 489     Fields:    Translation:HumansCells
    194. Dynamics of T cell responses in HIV infection. J Immunol. 2002 Apr 01; 168(7):3660-6. Appay V, Papagno L, Spina CA, Hansasuta P, King A, Jones L, Ogg GS, Little S, McMichael AJ, Richman DD, Rowland-Jones SL. PMID: 11907132.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansCells
    195. Transmission and prevalence of HIV resistance among treatment-naive subjects. Antivir Ther. 2000 Mar; 5(1):33-40. Little SJ. PMID: 10846591.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    196. Viral dynamics of acute HIV-1 infection. J Exp Med. 1999 Sep 20; 190(6):841-50. Little SJ, McLean AR, Spina CA, Richman DD, Havlir DV. PMID: 10499922.
      View in: PubMed   Mentions: 106     Fields:    Translation:HumansCells
    197. Reduced antiretroviral drug susceptibility among patients with primary HIV infection. JAMA. 1999 Sep 22-29; 282(12):1142-9. Little SJ, Daar ES, D'Aquila RT, Keiser PH, Connick E, Whitcomb JM, Hellmann NS, Petropoulos CJ, Sutton L, Pitt JA, Rosenberg ES, Koup RA, Walker BD, Richman DD. PMID: 10501117.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansCells
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