Manuela Raffatellu

Title(s)Professor, Pediatrics
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Collapse Biography 
    Collapse Education and Training
    University of California, Davis, Davis, CA09/2008Microbial pathogenesis
    Texas A&M University, College Station/Texas03/2005Microbial Pathogenesis
    University of Sassari, ItalyM.D.01/2000Medicine

    Collapse Overview 

    Collapse Research 
    Collapse Research Activities and Funding
    Antimicrobial activity of Escherichia coli Nissle 1917 microcin M
    NIH R21AI154644Jul 7, 2020 - Jun 30, 2022
    Role: Principal Investigator
    C3-Dependent Intracellular Killing in Innate Immunity and Bacterial Pathogenesis
    NIH R01AI145325Mar 5, 2019 - Feb 29, 2024
    Role: Principal Investigator
    Siderophore-based antibiotics: consequences for the microbiota and bacterial pathogens
    NIH R21AI126465Jun 10, 2016 - May 31, 2018
    Role: Co-Principal Investigator
    Nutritional immunity during Salmonella infection
    NIH R01AI126277May 15, 2016 - Apr 30, 2021
    Role: Principal Investigator
    The new chemokine CCL28 and its role during Salmonella infection
    NIH R21AI121928Jan 1, 2016 - Mar 31, 2019
    Role: Principal Investigator
    Development of siderophore-based vaccines against non-typhoidal Salmonella infection
    NIH R01AI114625Jun 1, 2015 - May 31, 2021
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Featured Publications
    Collapse Faculty Mentoring

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Selective IL-27 production by intestinal regulatory T cells permits gut-specific regulation of Th17 immunity. bioRxiv. 2023 Feb 21. Lin CH, Wu CJ, Cho S, Patkar R, Lin LL, Chen MC, Israelsson E, Betts J, Niedzielska M, Patel SA, Duong HG, Gerner RR, Hsu CY, Catley M, Maciewicz RA, Chu H, Raffatellu M, Chang JT, Lu LF. PMID: 36865314; PMCID: PMC9980002.
      View in: PubMed   Mentions:
    2. The Vi Capsular Polysaccharide of Salmonella Typhi Promotes Macrophage Phagocytosis by Binding the Human C-Type Lectin DC-SIGN. mBio. 2022 Oct 26; e0273322. Zhang LF, Lepenies B, Nakamae S, Young BM, Santos RL, Raffatellu M, Cobb BA, Hiyoshi H, B?umler AJ. PMID: 36286551; PMCID: PMC9765441.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    3. Siderophore Immunization Restricted Colonization of Adherent-Invasive Escherichia coli and Ameliorated Experimental Colitis. mBio. 2022 10 26; 13(5):e0218422. Gerner RR, Hossain S, Sargun A, Siada K, Norton GJ, Zheng T, Neumann W, Nuccio SP, Nolan EM, Raffatellu M. PMID: 36094114; PMCID: PMC9600343.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCellsPHPublic Health
    4. Age-associated impairment of T cell immunity is linked to sex-dimorphic elevation of N-glycan branching. Nat Aging. 2022 Mar; 2(3):231-242. Mkhikian H, Hayama KL, Khachikyan K, Li C, Zhou RW, Pawling J, Klaus S, Tran PQN, Ly KM, Gong AD, Saryan H, Hai JL, Grigoryan D, Lee PL, Newton BL, Raffatellu M, Dennis JW, Demetriou M. PMID: 35528547; PMCID: PMC9075523.
      View in: PubMed   Mentions: 3  
    5. Salmonella respiration turns the tables on propionate. Trends Microbiol. 2022 03; 30(3):206-208. Walker GT, Raffatellu M. PMID: 35123878; PMCID: PMC9000922.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    6. Multi-omics analyses of the ulcerative colitis gut microbiome link Bacteroides vulgatus proteases with disease severity. Nat Microbiol. 2022 02; 7(2):262-276. Mills RH, Dulai PS, V?zquez-Baeza Y, Sauceda C, Daniel N, Gerner RR, Batachari LE, Malfavon M, Zhu Q, Weldon K, Humphrey G, Carrillo-Terrazas M, Goldasich LD, Bryant M, Raffatellu M, Quinn RA, Gewirtz AT, Chassaing B, Chu H, Sandborn WJ, Dorrestein PC, Knight R, Gonzalez DJ. PMID: 35087228; PMCID: PMC8852248.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    7. Siderophore-mediated zinc acquisition enhances enterobacterial colonization of the inflamed gut. Nat Commun. 2021 12 01; 12(1):7016. Behnsen J, Zhi H, Aron AT, Subramanian V, Santus W, Lee MH, Gerner RR, Petras D, Liu JZ, Green KD, Price SL, Camacho J, Hillman H, Tjokrosurjo J, Montaldo NP, Hoover EM, Treacy-Abarca S, Gilston BA, Skaar EP, Chazin WJ, Garneau-Tsodikova S, Lawrenz MB, Perry RD, Nuccio SP, Dorrestein PC, Raffatellu M. PMID: 34853318; PMCID: PMC8636617.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    8. Native mass spectrometry-based metabolomics identifies metal-binding compounds. Nat Chem. 2022 01; 14(1):100-109. Aron AT, Petras D, Schmid R, Gauglitz JM, B?ttel I, Antelo L, Zhi H, Nuccio SP, Saak CC, Malarney KP, Thines E, Dutton RJ, Aluwihare LI, Raffatellu M, Dorrestein PC. PMID: 34795435; PMCID: PMC8959065.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
    9. Special Collection on the Microbiome and Infection. Infect Immun. 2021 08 16; 89(9):e0035621. Raffatellu M, B?umler AJ. PMID: 34280036; PMCID: PMC8370675.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    10. Ion identity molecular networking for mass spectrometry-based metabolomics in the GNPS environment. Nat Commun. 2021 06 22; 12(1):3832. Schmid R, Petras D, Nothias LF, Wang M, Aron AT, Jagels A, Tsugawa H, Rainer J, Garcia-Aloy M, D?hrkop K, Korf A, Pluskal T, Kamen?k Z, Jarmusch AK, Caraballo-Rodr?guez AM, Weldon KC, Nothias-Esposito M, Aksenov AA, Bauermeister A, Albarracin Orio A, Grundmann CO, Vargas F, Koester I, Gauglitz JM, Gentry EC, H?velmann Y, Kalinina SA, Pendergraft MA, Panitchpakdi M, Tehan R, Le Gouellec A, Aleti G, Mannochio Russo H, Arndt B, H?bner F, Hayen H, Zhi H, Raffatellu M, Prather KA, Aluwihare LI, B?cker S, McPhail KL, Humpf HU, Karst U, Dorrestein PC. PMID: 34158495; PMCID: PMC8219731.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    11. Harnessing Iron Acquisition Machinery to Target Enterobacteriaceae. J Infect Dis. 2021 06 16; 223(12 Suppl 2):S307-S313. Sargun A, Gerner RR, Raffatellu M, Nolan EM. PMID: 33330928; PMCID: PMC8427712.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    12. Conjugation to Enterobactin and Salmochelin S4 Enhances the Antimicrobial Activity and Selectivity of �-Lactam Antibiotics against Nontyphoidal Salmonella. ACS Infect Dis. 2021 05 14; 7(5):1248-1259. Sargun A, Sassone-Corsi M, Zheng T, Raffatellu M, Nolan EM. PMID: 33691061; PMCID: PMC8122056.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    13. Enterobactin- and salmochelin-�-lactam conjugates induce cell morphologies consistent with inhibition of penicillin-binding proteins in uropathogenic Escherichia coli CFT073. Chem Sci. 2021 Jan 13; 12(11):4041-4056. Sargun A, Johnstone TC, Zhi H, Raffatellu M, Nolan EM. PMID: 34163675; PMCID: PMC8179508.
      View in: PubMed   Mentions: 2  
    14. The interaction of enteric bacterial effectors with the host engulfment pathway control innate immune responses. Gut Microbes. 2021 Jan-Dec; 13(1):1991776. Sayed IM, Ibeawuchi SR, Lie D, Anandachar MS, Pranadinata R, Raffatellu M, Das S. PMID: 34719317; PMCID: PMC8565811.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    15. Call for Original Research Papers for a Special Collection in Infection and Immunity: the Microbiome and Infection. Infect Immun. 2020 11 16; 88(12). Raffatellu M, B?umler AJ. PMID: 32989038; PMCID: PMC7671895.
      View in: PubMed   Mentions:    Fields:    
    16. CD8 T cells drive anorexia, dysbiosis, and blooms of a commensal with immunosuppressive potential after viral infection. Proc Natl Acad Sci U S A. 2020 10 06; 117(40):24998-25007. Labarta-Bajo L, Gramalla-Schmitz A, Gerner RR, Kazane KR, Humphrey G, Schwartz T, Sanders K, Swafford A, Knight R, Raffatellu M, Z??iga EI. PMID: 32958643; PMCID: PMC7547153.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    17. Iron at the host-microbe interface. Mol Aspects Med. 2020 10; 75:100895. Gerner RR, Nuccio SP, Raffatellu M. PMID: 32883564; PMCID: PMC7554189.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimals
    18. Pathogen Interference: Targeting Virulence Factors to Tackle Intracellular Microbes. Cell Chem Biol. 2020 07 16; 27(7):765-767. Lee MH, Nuccio SP, Raffatellu M. PMID: 32679090.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    19. Targeted Depletion of Bacteria from Mixed Populations by Programmable Adhesion with Antagonistic Competitor Cells. Cell Host Microbe. 2020 08 12; 28(2):313-321.e6. Ting SY, Mart?nez-Garc?a E, Huang S, Bertolli SK, Kelly KA, Cutler KJ, Su ED, Zhi H, Tang Q, Radey MC, Raffatellu M, Peterson SB, de Lorenzo V, Mougous JD. PMID: 32470328; PMCID: PMC7725374.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    20. Gut pain sensors help to combat infection. Nature. 2020 04; 580(7805):594-595. Gerner RR, Raffatellu M. PMID: 32313162.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    21. Global chemical effects of the microbiome include new bile-acid conjugations. Nature. 2020 03; 579(7797):123-129. Quinn RA, Melnik AV, Vrbanac A, Fu T, Patras KA, Christy MP, Bodai Z, Belda-Ferre P, Tripathi A, Chung LK, Downes M, Welch RD, Quinn M, Humphrey G, Panitchpakdi M, Weldon KC, Aksenov A, da Silva R, Avila-Pacheco J, Clish C, Bae S, Mallick H, Franzosa EA, Lloyd-Price J, Bussell R, Thron T, Nelson AT, Wang M, Leszczynski E, Vargas F, Gauglitz JM, Meehan MJ, Gentry E, Arthur TD, Komor AC, Poulsen O, Boland BS, Chang JT, Sandborn WJ, Lim M, Garg N, Lumeng JC, Xavier RJ, Kazmierczak BI, Jain R, Egan M, Rhee KE, Ferguson D, Raffatellu M, Vlamakis H, Haddad GG, Siegel D, Huttenhower C, Mazmanian SK, Evans RM, Nizet V, Knight R, Dorrestein PC. PMID: 32103176; PMCID: PMC7252668.
      View in: PubMed   Mentions: 126     Fields:    Translation:HumansAnimals
    22. CRTAM Shapes the Gut Microbiota and Enhances the Severity of Infection. J Immunol. 2019 07 15; 203(2):532-543. Perez-Lopez A, Nuccio SP, Ushach I, Edwards RA, Pahu R, Silva S, Zlotnik A, Raffatellu M. PMID: 31142601; PMCID: PMC6615957.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    23. CCL28 Is Involved in Mucosal IgA Responses, Olfaction, and Resistance to Enteric Infections. J Interferon Cytokine Res. 2019 04; 39(4):214-223. Burkhardt AM, Perez-Lopez A, Ushach I, Catalan-Dibene J, Nuccio SP, Chung LK, Hernandez-Ruiz M, Carnevale C, Raffatellu M, Zlotnik A. PMID: 30855201; PMCID: PMC6479244.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    24. Probiotic fengycins dis(Agr)ee with Staphylococcus aureus colonization. Cell Res. 2019 02; 29(2):93-94. Chung LK, Raffatellu M. PMID: 30607015; PMCID: PMC6355905.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    25. Genome-scale metabolic reconstructions of multiple Salmonella strains reveal serovar-specific metabolic traits. Nat Commun. 2018 09 14; 9(1):3771. Seif Y, Kavvas E, Lachance JC, Yurkovich JT, Nuccio SP, Fang X, Catoiu E, Raffatellu M, Palsson BO, Monk JM. PMID: 30218022; PMCID: PMC6138749.
      View in: PubMed   Mentions: 44     Fields:    Translation:Cells
    26. Learning from bacterial competition in the host to develop antimicrobials. Nat Med. 2018 08; 24(8):1097-1103. Raffatellu M. PMID: 30082869.
      View in: PubMed   Mentions: 27     Fields:    Translation:Cells
    27. Defining Host Responses during Systemic Bacterial Infection through Construction of a Murine Organ Proteome Atlas. Cell Syst. 2018 05 23; 6(5):579-592.e4. Lapek JD, Mills RH, Wozniak JM, Campeau A, Fang RH, Wei X, van de Groep K, Perez-Lopez A, van Sorge NM, Raffatellu M, Knight R, Zhang L, Gonzalez DJ. PMID: 29778837; PMCID: PMC7868092.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    28. A Worm's Gut Feelings: Neuronal Muscarinic and Epithelial Canonical Wnt Pathways Promote Antimicrobial Defense. Immunity. 2018 05 15; 48(5):839-841. Gerner RR, Raffatellu M. PMID: 29768168.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    29. Esterase-Catalyzed Siderophore Hydrolysis Activates an Enterobactin-Ciprofloxacin Conjugate and Confers Targeted Antibacterial Activity. J Am Chem Soc. 2018 04 18; 140(15):5193-5201. Neumann W, Sassone-Corsi M, Raffatellu M, Nolan EM. PMID: 29578687; PMCID: PMC5921047.
      View in: PubMed   Mentions: 35     Fields:    Translation:Cells
    30. Mechanisms to Evade the Phagocyte Respiratory Burst Arose by Convergent Evolution in Typhoidal Salmonella Serovars. Cell Rep. 2018 02 13; 22(7):1787-1797. Hiyoshi H, Wangdi T, Lock G, Saechao C, Raffatellu M, Cobb BA, B?umler AJ. PMID: 29444431; PMCID: PMC5826628.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    31. G.I. pros: Antimicrobial defense in the gastrointestinal tract. Semin Cell Dev Biol. 2019 04; 88:129-137. Chung LK, Raffatellu M. PMID: 29432952; PMCID: PMC6087682.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimals
    32. Identification of IL-40, a Novel B Cell-Associated Cytokine. J Immunol. 2017 11 01; 199(9):3326-3335. Catalan-Dibene J, Vazquez MI, Luu VP, Nuccio SP, Karimzadeh A, Kastenschmidt JM, Villalta SA, Ushach I, Pone EJ, Casali P, Raffatellu M, Burkhardt AM, Hernandez-Ruiz M, Heller G, Hevezi PA, Zlotnik A. PMID: 28978694; PMCID: PMC5667921.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    33. Bariatric surgery attenuates colitis in an obese murine model. Surg Obes Relat Dis. 2017 Apr; 13(4):661-668. Li S, Vinci A, Behnsen J, Cheng C, Jellbauer S, Raffatellu M, Sousa KM, Edwards R, Nguyen NT, Stamos MJ, Pigazzi A. PMID: 28185763; PMCID: PMC7847609.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    34. Cytokines IL-17 and IL-22 in the host response to infection. Pathog Dis. 2016 12; 74(9). Valeri M, Raffatellu M. PMID: 27915228; PMCID: PMC5975231.
      View in: PubMed   Mentions: 76     Fields:    Translation:HumansAnimals
    35. Siderophores: More than Stealing Iron. mBio. 2016 11 15; 7(6). Behnsen J, Raffatellu M. PMID: 27935843; PMCID: PMC5111413.
      View in: PubMed   Mentions: 30     Fields:    Translation:Cells
    36. Siderophore-based immunization strategy to inhibit growth of enteric pathogens. Proc Natl Acad Sci U S A. 2016 11 22; 113(47):13462-13467. Sassone-Corsi M, Chairatana P, Zheng T, Perez-Lopez A, Edwards RA, George MD, Nolan EM, Raffatellu M. PMID: 27821741; PMCID: PMC5127304.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCellsPHPublic Health
    37. Microcins mediate competition among Enterobacteriaceae in the inflamed gut. Nature. 2016 12 08; 540(7632):280-283. Sassone-Corsi M, Nuccio SP, Liu H, Hernandez D, Vu CT, Takahashi AA, Edwards RA, Raffatellu M. PMID: 27798599; PMCID: PMC5145735.
      View in: PubMed   Mentions: 179     Fields:    Translation:AnimalsCells
    38. Beneficial Effects of Sodium Phenylbutyrate Administration during Infection with Salmonella enterica Serovar Typhimurium. Infect Immun. 2016 09; 84(9):2639-52. Jellbauer S, Perez Lopez A, Behnsen J, Gao N, Nguyen T, Murphy C, Edwards RA, Raffatellu M. PMID: 27382022; PMCID: PMC4995890.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    39. Close encounters of the type-six kind: injected bacterial toxins modulate gut microbial composition. EMBO Rep. 2016 09; 17(9):1242-4. Sassone-Corsi M, Raffatellu M. PMID: 27506890; PMCID: PMC5007567.
      View in: PubMed   Mentions:    Fields:    
    40. Salmonella Mitigates Oxidative Stress and Thrives in the Inflamed Gut by Evading Calprotectin-Mediated Manganese Sequestration. Cell Host Microbe. 2016 Jun 08; 19(6):814-25. Diaz-Ochoa VE, Lam D, Lee CS, Klaus S, Behnsen J, Liu JZ, Chim N, Nuccio SP, Rathi SG, Mastroianni JR, Edwards RA, Jacobo CM, Cerasi M, Battistoni A, Ouellette AJ, Goulding CW, Chazin WJ, Skaar EP, Raffatellu M. PMID: 27281571; PMCID: PMC4901528.
      View in: PubMed   Mentions: 75     Fields:    Translation:AnimalsCells
    41. Mucosal immunity to pathogenic intestinal bacteria. Nat Rev Immunol. 2016 Mar; 16(3):135-48. Perez-Lopez A, Behnsen J, Nuccio SP, Raffatellu M. PMID: 26898110.
      View in: PubMed   Mentions: 122     Fields:    Translation:HumansCells
    42. Gut immune dysfunction through impaired innate pattern recognition receptor expression and gut microbiota dysbiosis in chronic SIV infection. Mucosal Immunol. 2016 05; 9(3):677-88. Glavan TW, Gaulke CA, Santos Rocha C, Sankaran-Walters S, Hirao LA, Raffatellu M, Jiang G, B?umler AJ, Goulart LR, Dandekar S. PMID: 26376368; PMCID: PMC4794436.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansAnimalsCells
    43. Metals in infectious diseases and nutritional immunity. Metallomics. 2015 Jun; 7(6):926-8. Skaar EP, Raffatellu M. PMID: 26017093.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimalsCells
    44. Salmonella infection inhibits intestinal biotin transport: cellular and molecular mechanisms. Am J Physiol Gastrointest Liver Physiol. 2015 Jul 15; 309(2):G123-31. Ghosal A, Jellbauer S, Kapadia R, Raffatellu M, Said HM. PMID: 25999427; PMCID: PMC4504957.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    45. No vacancy: how beneficial microbes cooperate with immunity to provide colonization resistance to pathogens. J Immunol. 2015 May 01; 194(9):4081-7. Sassone-Corsi M, Raffatellu M. PMID: 25888704; PMCID: PMC4402713.
      View in: PubMed   Mentions: 123     Fields:    Translation:HumansAnimalsCells
    46. Exploiting host immunity: the Salmonella paradigm. Trends Immunol. 2015 Feb; 36(2):112-20. Behnsen J, Perez-Lopez A, Nuccio SP, Raffatellu M. PMID: 25582038; PMCID: PMC4323876.
      View in: PubMed   Mentions: 57     Fields:    Translation:HumansAnimalsCells
    47. mTOR kinase inhibitors promote antibody class switching via mTORC2 inhibition. Proc Natl Acad Sci U S A. 2014 Nov 25; 111(47):E5076-85. Limon JJ, So L, Jellbauer S, Chiu H, Corado J, Sykes SM, Raffatellu M, Fruman DA. PMID: 25385646; PMCID: PMC4250172.
      View in: PubMed   Mentions: 39     Fields:    Translation:AnimalsCells
    48. Nutritional iron turned inside out: intestinal stress from a gut microbial perspective. FEMS Microbiol Rev. 2014 Nov; 38(6):1202-34. Kortman GA, Raffatellu M, Swinkels DW, Tjalsma H. PMID: 25205464.
      View in: PubMed   Mentions: 95     Fields:    Translation:HumansCells
    49. The ZupT transporter plays an important role in zinc homeostasis and contributes to Salmonella enterica virulence. Metallomics. 2014 Apr; 6(4):845-53. Cerasi M, Liu JZ, Ammendola S, Poe AJ, Petrarca P, Pesciaroli M, Pasquali P, Raffatellu M, Battistoni A. PMID: 24430377; PMCID: PMC3969385.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    50. Response to Gerlic et al. Cell Metab. 2014 Mar 04; 19(3):346-7. Im SS, Young SG, Raffatellu M, Osborne TF. PMID: 24606892.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    51. The cytokine IL-22 promotes pathogen colonization by suppressing related commensal bacteria. Immunity. 2014 Feb 20; 40(2):262-73. Behnsen J, Jellbauer S, Wong CP, Edwards RA, George MD, Ouyang W, Raffatellu M. PMID: 24508234; PMCID: PMC3964146.
      View in: PubMed   Mentions: 150     Fields:    Translation:AnimalsCells
    52. Transition metal ions at the crossroads of mucosal immunity and microbial pathogenesis. Front Cell Infect Microbiol. 2014; 4:2. Diaz-Ochoa VE, Jellbauer S, Klaus S, Raffatellu M. PMID: 24478990; PMCID: PMC3900919.
      View in: PubMed   Mentions: 62     Fields:    Translation:HumansAnimalsCells
    53. A hydrogen boost for salmonella. Cell Host Microbe. 2013 Dec 11; 14(6):603-4. Sassone-Corsi M, Raffatellu M. PMID: 24331457.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    54. An intestinal arsonist: pathobiont ignites IBD and flees the scene. Gut. 2014 Jul; 63(7):1034-5. Jellbauer S, Raffatellu M. PMID: 24026350.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    55. Keeping the peace: aryl hydrocarbon receptor signaling modulates the mucosal microbiota. Immunity. 2013 Aug 22; 39(2):206-7. Behnsen J, Raffatellu M. PMID: 23973218.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    56. Probiotic bacteria reduce salmonella typhimurium intestinal colonization by competing for iron. Cell Host Microbe. 2013 Jul 17; 14(1):26-37. Deriu E, Liu JZ, Pezeshki M, Edwards RA, Ochoa RJ, Contreras H, Libby SJ, Fang FC, Raffatellu M. PMID: 23870311; PMCID: PMC3752295.
      View in: PubMed   Mentions: 180     Fields:    Translation:HumansAnimalsCells
    57. Attenuated Salmonella enterica serovar Typhimurium lacking the ZnuABC transporter: an efficacious orally-administered mucosal vaccine against salmonellosis in pigs. Vaccine. 2013 Aug 12; 31(36):3695-701. Gradassi M, Pesciaroli M, Martinelli N, Ruggeri J, Petrucci P, Hassan WH, Raffatellu M, Scaglione FE, Ammendola S, Battistoni A, Alborali GL, Pasquali P. PMID: 23770333; PMCID: PMC3880306.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    58. Circadian clock regulates the host response to Salmonella. Proc Natl Acad Sci U S A. 2013 Jun 11; 110(24):9897-902. Bellet MM, Deriu E, Liu JZ, Grimaldi B, Blaschitz C, Zeller M, Edwards RA, Sahar S, Dandekar S, Baldi P, George MD, Raffatellu M, Sassone-Corsi P. PMID: 23716692; PMCID: PMC3683799.
      View in: PubMed   Mentions: 119     Fields:    Translation:AnimalsCells
    59. Salmonella Typhimurium lacking the Znuabc transporter is attenuated and immunogenic in pigs. Vaccine. 2013 Jun 12; 31(27):2868-73. Pesciaroli M, Gradassi M, Martinelli N, Ruggeri J, Pistoia C, Raffatellu M, Magistrali CF, Battistoni A, Pasquali P, Alborali GL. PMID: 23623860; PMCID: PMC3874890.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCellsPHPublic Health
    60. Probiotics: properties, examples, and specific applications. Cold Spring Harb Perspect Med. 2013 Mar 01; 3(3):a010074. Behnsen J, Deriu E, Sassone-Corsi M, Raffatellu M. PMID: 23457295; PMCID: PMC3579206.
      View in: PubMed   Mentions: 84     Fields:    Translation:Humans
    61. Uremic plasma impairs barrier function and depletes the tight junction protein constituents of intestinal epithelium. Am J Nephrol. 2012; 36(5):438-43. Vaziri ND, Goshtasbi N, Yuan J, Jellbauer S, Moradi H, Raffatellu M, Kalantar-Zadeh K. PMID: 23128155; PMCID: PMC3725306.
      View in: PubMed   Mentions: 56     Fields:    Translation:HumansCells
    62. Zinc sequestration by the neutrophil protein calprotectin enhances Salmonella growth in the inflamed gut. Cell Host Microbe. 2012 Mar 15; 11(3):227-39. Liu JZ, Jellbauer S, Poe AJ, Ton V, Pesciaroli M, Kehl-Fie TE, Restrepo NA, Hosking MP, Edwards RA, Battistoni A, Pasquali P, Lane TE, Chazin WJ, Vogl T, Roth J, Skaar EP, Raffatellu M. PMID: 22423963; PMCID: PMC3308348.
      View in: PubMed   Mentions: 191     Fields:    Translation:AnimalsCells
    63. Linking lipid metabolism to the innate immune response in macrophages through sterol regulatory element binding protein-1a. Cell Metab. 2011 May 04; 13(5):540-9. Im SS, Yousef L, Blaschitz C, Liu JZ, Edwards RA, Young SG, Raffatellu M, Osborne TF. PMID: 21531336; PMCID: PMC3090630.
      View in: PubMed   Mentions: 150     Fields:    Translation:AnimalsCells
    64. Enteric pathology and Salmonella-induced cell death in healthy and SIV-infected rhesus macaques. Vet Pathol. 2011 Sep; 48(5):933-41. Santos RL, Almeida AP, Xavier MN, Paix?o TA, Wilson RP, Dandekar S, Raffatellu M, B?umler AJ. PMID: 21041540.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    65. Th17 cytokines and the gut mucosal barrier. J Clin Immunol. 2010 Mar; 30(2):196-203. Blaschitz C, Raffatellu M. PMID: 20127275; PMCID: PMC2842875.
      View in: PubMed   Mentions: 106     Fields:    Translation:HumansAnimalsCells
    66. Salmonella's iron armor for battling the host and its microbiota. Gut Microbes. 2010 Jan; 1(1):70-72. Raffatellu M, B?umler AJ. PMID: 21327120; PMCID: PMC3035136.
      View in: PubMed   Mentions: 12     Fields:    
    67. The Salmonella enterica serotype Typhi Vi capsular antigen is expressed after the bacterium enters the ileal mucosa. Infect Immun. 2010 Jan; 78(1):527-35. Tran QT, Gomez G, Khare S, Lawhon SD, Raffatellu M, Bäumler AJ, Ajithdoss D, Dhavala S, Adams LG. PMID: 19901065; PMCID: PMC2798196.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    68. Life in the inflamed intestine, Salmonella style. Trends Microbiol. 2009 Nov; 17(11):498-506. Santos RL, Raffatellu M, Bevins CL, Adams LG, Tükel C, Tsolis RM, Bäumler AJ. PMID: 19819699; PMCID: PMC3235402.
      View in: PubMed   Mentions: 88     Fields:    Translation:HumansAnimalsCells
    69. Th17 cytokines and host-pathogen interactions at the mucosa: dichotomies of help and harm. Cytokine. 2009 Oct-Nov; 48(1-2):156-60. Liu JZ, Pezeshki M, Raffatellu M. PMID: 19665391; PMCID: PMC2836905.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    70. Salmonella enterica serovar Typhimurium-induced internalization and IL-8 expression in HeLa cells does not have a direct relationship with intracellular Ca(2+) levels. Microbes Infect. 2009 Sep; 11(10-11):850-8. Figueiredo JF, Barhoumi R, Raffatellu M, Lawhon SD, Rousseau B, Burghardt RC, Tsolis RM, Bäumler AJ, Adams LG. PMID: 19450704; PMCID: PMC2742474.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    71. Lipocalin-2 resistance confers an advantage to Salmonella enterica serotype Typhimurium for growth and survival in the inflamed intestine. Cell Host Microbe. 2009 May 08; 5(5):476-86. Raffatellu M, George MD, Akiyama Y, Hornsby MJ, Nuccio SP, Paixao TA, Butler BP, Chu H, Santos RL, Berger T, Mak TW, Tsolis RM, Bevins CL, Solnick JV, Dandekar S, Bäumler AJ. PMID: 19454351; PMCID: PMC2768556.
      View in: PubMed   Mentions: 270     Fields:    Translation:HumansAnimalsCells
    72. Salmonella enterica Typhimurium SipA induces CXC-chemokine expression through p38MAPK and JUN pathways. Microbes Infect. 2009 Feb; 11(2):302-10. Figueiredo JF, Lawhon SD, Gokulan K, Khare S, Raffatellu M, Tsolis RM, Bäumler AJ, McCormick BA, Adams LG. PMID: 19114119.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    73. Interleukin-23 orchestrates mucosal responses to Salmonella enterica serotype Typhimurium in the intestine. Infect Immun. 2009 Jan; 77(1):387-98. Godinez I, Raffatellu M, Chu H, Paixão TA, Haneda T, Santos RL, Bevins CL, Tsolis RM, Bäumler AJ. PMID: 18955477; PMCID: PMC2612270.
      View in: PubMed   Mentions: 81     Fields:    Translation:AnimalsCells
    74. Clinical pathogenesis of typhoid fever. J Infect Dev Ctries. 2008 Aug 30; 2(4):260-6. Raffatellu M, Wilson RP, Winter SE, Bäumler AJ. PMID: 19741286.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansCells
    75. Simian immunodeficiency virus-induced mucosal interleukin-17 deficiency promotes Salmonella dissemination from the gut. Nat Med. 2008 Apr; 14(4):421-8. Raffatellu M, Santos RL, Verhoeven DE, George MD, Wilson RP, Winter SE, Godinez I, Sankaran S, Paixao TA, Gordon MA, Kolls JK, Dandekar S, Bäumler AJ. PMID: 18376406; PMCID: PMC2901863.
      View in: PubMed   Mentions: 333     Fields:    Translation:HumansAnimalsCells
    76. T cells help to amplify inflammatory responses induced by Salmonella enterica serotype Typhimurium in the intestinal mucosa. Infect Immun. 2008 May; 76(5):2008-17. Godinez I, Haneda T, Raffatellu M, George MD, Paixão TA, Rolán HG, Santos RL, Dandekar S, Tsolis RM, Bäumler AJ. PMID: 18347048; PMCID: PMC2346712.
      View in: PubMed   Mentions: 77     Fields:    Translation:AnimalsCells
    77. The Salmonella enterica serotype Typhi regulator TviA reduces interleukin-8 production in intestinal epithelial cells by repressing flagellin secretion. Cell Microbiol. 2008 Jan; 10(1):247-61. Winter SE, Raffatellu M, Wilson RP, Rüssmann H, Bäumler AJ. PMID: 17725646.
      View in: PubMed   Mentions: 58     Fields:    Translation:HumansCells
    78. The Vi-capsule prevents Toll-like receptor 4 recognition of Salmonella. Cell Microbiol. 2008 Apr; 10(4):876-90. Wilson RP, Raffatellu M, Chessa D, Winter SE, Tükel C, Bäumler AJ. PMID: 18034866.
      View in: PubMed   Mentions: 73     Fields:    Translation:AnimalsCells
    79. The capsule encoding the viaB locus reduces interleukin-17 expression and mucosal innate responses in the bovine intestinal mucosa during infection with Salmonella enterica serotype Typhi. Infect Immun. 2007 Sep; 75(9):4342-50. Raffatellu M, Santos RL, Chessa D, Wilson RP, Winter SE, Rossetti CA, Lawhon SD, Chu H, Lau T, Bevins CL, Adams LG, Bäumler AJ. PMID: 17591794; PMCID: PMC1951168.
      View in: PubMed   Mentions: 59     Fields:    Translation:AnimalsCells
    80. SIMPLE approach for isolating mutants expressing fimbriae. Appl Environ Microbiol. 2007 Jul; 73(14):4455-62. Nuccio SP, Chessa D, Weening EH, Raffatellu M, Clegg S, Bäumler AJ. PMID: 17526787; PMCID: PMC1932825.
      View in: PubMed   Mentions: 10     Fields:    Translation:Cells
    81. Neutrophil influx during non-typhoidal salmonellosis: who is in the driver's seat? FEMS Immunol Med Microbiol. 2006 Apr; 46(3):320-9. Tükel C, Raffatellu M, Chessa D, Wilson RP, Akçelik M, Bäumler AJ. PMID: 16553804.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    82. Capsule-mediated immune evasion: a new hypothesis explaining aspects of typhoid fever pathogenesis. Infect Immun. 2006 Jan; 74(1):19-27. Raffatellu M, Chessa D, Wilson RP, Tükel C, Akçelik M, Bäumler AJ. PMID: 16368953; PMCID: PMC1346610.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansAnimalsCells
    83. Host restriction of Salmonella enterica serotype Typhi is not caused by functional alteration of SipA, SopB, or SopD. Infect Immun. 2005 Dec; 73(12):7817-26. Raffatellu M, Sun YH, Wilson RP, Tran QT, Chessa D, Andrews-Polymenis HL, Lawhon SD, Figueiredo JF, Tsolis RM, Adams LG, Bäumler AJ. PMID: 16299271; PMCID: PMC1307101.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    84. CsgA is a pathogen-associated molecular pattern of Salmonella enterica serotype Typhimurium that is recognized by Toll-like receptor 2. Mol Microbiol. 2005 Oct; 58(1):289-304. Tükel C, Raffatellu M, Humphries AD, Wilson RP, Andrews-Polymenis HL, Gull T, Figueiredo JF, Wong MH, Michelsen KS, Akçelik M, Adams LG, Bäumler AJ. PMID: 16164566.
      View in: PubMed   Mentions: 92     Fields:    Translation:HumansAnimalsCells
    85. The Vi capsular antigen of Salmonella enterica serotype Typhi reduces Toll-like receptor-dependent interleukin-8 expression in the intestinal mucosa. Infect Immun. 2005 Jun; 73(6):3367-74. Raffatellu M, Chessa D, Wilson RP, Dusold R, Rubino S, Bäumler AJ. PMID: 15908363; PMCID: PMC1111811.
      View in: PubMed   Mentions: 98     Fields:    Translation:HumansCells
    86. SipA, SopA, SopB, SopD, and SopE2 contribute to Salmonella enterica serotype typhimurium invasion of epithelial cells. Infect Immun. 2005 Jan; 73(1):146-54. Raffatellu M, Wilson RP, Chessa D, Andrews-Polymenis H, Tran QT, Lawhon S, Khare S, Adams LG, Bäumler AJ. PMID: 15618149; PMCID: PMC538951.
      View in: PubMed   Mentions: 124     Fields:    Translation:HumansAnimalsCells
    87. The use of flow cytometry to detect expression of subunits encoded by 11 Salmonella enterica serotype Typhimurium fimbrial operons. Mol Microbiol. 2003 Jun; 48(5):1357-76. Humphries AD, Raffatellu M, Winter S, Weening EH, Kingsley RA, Droleskey R, Zhang S, Figueiredo J, Khare S, Nunes J, Adams LG, Tsolis RM, Bäumler AJ. PMID: 12787362.
      View in: PubMed   Mentions: 81     Fields:    Translation:AnimalsCells
    88. Molecular pathogenesis of Salmonella enterica serotype typhimurium-induced diarrhea. Infect Immun. 2003 Jan; 71(1):1-12. Zhang S, Kingsley RA, Santos RL, Andrews-Polymenis H, Raffatellu M, Figueiredo J, Nunes J, Tsolis RM, Adams LG, Bäumler AJ. PMID: 12496143; PMCID: PMC143292.
      View in: PubMed   Mentions: 117     Fields:    Translation:HumansAnimalsCells
    89. IS200 fingerprinting of Salmonella enterica serotype Abortusovis strains isolated in Iran. Epidemiol Infect. 2002 Apr; 128(2):333-6. Nikbakht GH, Raffatellu M, Uzzau S, Tadjbakhsh H, Rubino S. PMID: 12002552; PMCID: PMC2869827.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
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