Imanuel Lerman

Title(s)Associate Clinical Professor, Anesthesiology
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Collapse Biography 
    Collapse Education and Training
    Massachusetts General Hospital , Boston, MAFellowship 07/2012Pain Medicine
    Yale School of Medicine , New Haven, CTResident 07/2011Neurology
    Yale School of Medicine , New Haven, CTResident 07/2008Internal Medicine
    Georgetown School of Medicine , District of Columbia MD 06/2007Medicine
    Georgetown University , District of Columbia MSc07/2004Physiology and Biophysics
    University of Colorado , Boulder BA06/2000Molecular Cellular Developmental Biology, Kinesiolgy and Applied Physiology
    Collapse Awards and Honors
    Georgetown University School of Medicine 2003  - 2004Exceptional Service Award
    Georgetown University School of Medicine 2004  - 2007Thomas Auth M.D. Excellence in Neurology Award
    Brain and Behavior Foundation 2014  - 2015NARSAD Young Investigator Award
    University of California San Diego, Anesthesiology Department 2016  - 2017Pain Fellowship Teaching Award

    Collapse Overview 
    Collapse Overview
    As an associate professor in the Department of Anesthesiology at UC San Diego School of Medicine, Dr. Lerman carries out numerous clinical trials at UC San Diego Medical Center, the Altman Clinical Trial Research Institute, and the VA San Diego Healthcare System. His clinical reasarch studies primarily focus on understanding the impact of neurotechnologies (e.g. spinal cord stimulation, vagal nerve stimulation, and other central and peripheral nerve stimulation) on pain, learning and mental health disorders.

    He uses techniques such as functional magnetic resonance imaging (fMRI) and magnetoencephalography (MEG); inflammatory profiling of cerebrospinal fluid and peripheral blood; and high resolution evaluation of peripheral autonomic nervous system to better understand the interplay between pain and inflammation in the central and peripheral nervous system, in both healthy and disease states.

    Dr. Lerman completed his fellowship in pain management at Massachusetts General Hospital and his neurology residency at Yale School of Medicine. He earned his medical degree from Georgetown University School of Medicine, where he also obtained a master's degree in physiology and biophysics. He is triple board certified in neurology, pain medicine and headache medicine (United Council for Neurologic Subspecialties).

    Dr. Lerman is a founding board member of the American Interventional Headache Society, faculty and founding member of the Regenerative Medicine special interest group within the American Society of Regional Anesthesiology and Pain Medicine, and faculty member for the World Academy of Pain Medicine Ultrasonography.

    Collapse Research 
    Collapse Research Activities and Funding
    Novel Vagus Nerve Signaling to Improve Learning Throughout Adverse Sleep Challenge (NOVEL-TASC)
    Defense Advanced Research Projects Agency (DARPA) W911NF2010027Apr 1, 2020 - Sep 1, 2021
    Role: PI
    In-Vivo Vagus Sentinels to Detect and Prevent Infection
    BARDA HHS 7515011900038Aug 1, 2019 - Feb 28, 2021
    Role: Principle Investigator
    Vagal nerve stimulation to probe inflammation and brain in posttraumatic stress
    VA IK2RX002920Apr 1, 2019 - Mar 31, 2024
    Role: Principal Investigator
    Vagal Nerve Stimulation to Probe Inflammation and Brain in Post-traumatic Stress
    Department of Veterans Affairs, Rehabilitation Research and Development Service IK2 RX002920Jan 10, 2019 - Dec 31, 2023
    Role: Principle Investigator
    Role Description: Career Development Award (CDA-2)
    Effects of High Frequency Spinal Cord Stimulation As Measured by Autonomic Tone and Functional Brain Imaging
    NEVRO LLC 20172749Sep 1, 2018
    Role: Principle Investigator
    Focused Ultrasound For Nerve Stimulation
    Katz Neural Engineering Fund 86M45AApr 1, 2018 - Mar 9, 2019
    Role: Principle Investigator

    Collapse ORNG Applications 
    Collapse Clinical Trials
    Collapse Websites
    Collapse In The News

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Effects of Noninvasive Cervical Vagal Nerve Stimulation on Cognitive Performance But Not Brain Activation in Healthy Adults. Neuromodulation. 2020 Nov 25. Klaming R, Simmons AN, Spadoni AD, Lerman I. PMID: 33236815.
      View in: PubMed   Mentions:    Fields:    
    2. Ultrasound-Guided Cervical Medial Branch Blocks: A Systematic Review and Meta-Analysis. Article. 2020; 01( 03):1-12. Stephania Paredes MD, Roderick J. Finlayson MD, Samer Narouze MD PhD , Sameh M Hakim MD MSc (Pain) MSc (Anesth) PGDipM DipBiostat, , Daniel Adams PA-C MSHS DMA, Nimish Mittal MBBS MD MSc, Michael Catapano BHSc MD, Lynn Kohan MD, Patrick Connell BSc, Nebojsa Nick Knezevic MD PhD, Alex Feoktistov MD PhD, Imanuel Lerman MD MSc, Antoun Nader MD, Dmitri Souza MD PhD. View Publication.
    3. Marked Increases in Resting-State MEG Gamma-Band Activity in Combat-Related Mild Traumatic Brain Injury. Cereb Cortex. 2020 01 10; 30(1):283-295. Huang MX, Huang CW, Harrington DL, Nichols S, Robb-Swan A, Angeles-Quinto A, Le L, Rimmele C, Drake A, Song T, Huang JW, Clifford R, Ji Z, Cheng CK, Lerman I, Yurgil KA, Lee RR, Baker DG. PMID: 31041986.
      View in: PubMed   Mentions:    Fields:    
    4. A Letter to the Editor: Impact of Neck Position on the Probability of Common Carotid Artery Puncture during Ultrasound-Guided Stellate Ganglion Block. PM R. 2019 11; 11(11):1250-1251. Reddy R, Lerman I, Chen J. PMID: 31397974.
      View in: PubMed   Mentions: 1     Fields:    
    5. Spinal cord stimulation in chronic pain: evidence and theory for mechanisms of action. Bioelectron Med. 2019 Jun 28; 5. Caylor J, Reddy R, Yin S, Cui C, Huang M, Huang C, Ramesh R, Baker DG, Simmons A, Souza D, Narouze S, Vallejo R, Lerman I. PMID: 31435499.
      View in: PubMed   Mentions:
    6. MEG Working Memory N-Back Task Reveals Functional Deficits in Combat-Related Mild Traumatic Brain Injury. Cereb Cortex. 2019 05 01; 29(5):1953-1968. Huang MX, Nichols S, Robb-Swan A, Angeles-Quinto A, Harrington DL, Drake A, Huang CW, Song T, Diwakar M, Risbrough VB, Matthews S, Clifford R, Cheng CK, Huang JW, Sinha A, Yurgil KA, Ji Z, Lerman I, Lee RR, Baker DG. PMID: 29668852.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    7. Noninvasive vagus nerve stimulation alters neural response and physiological autonomic tone to noxious thermal challenge. PLoS One. 2019; 14(2):e0201212. Lerman I, Davis B, Huang M, Huang C, Sorkin L, Proudfoot J, Zhong E, Kimball D, Rao R, Simon B, Spadoni A, Strigo I, Baker DG, Simmons AN. PMID: 30759089.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    8. Relations of combat stress and posttraumatic stress disorder to 24-h plasma and cerebrospinal fluid interleukin-6 levels and circadian rhythmicity. Psychoneuroendocrinology. 2019 02; 100:237-245. Agorastos A, Hauger RL, Barkauskas DA, Lerman IR, Moeller-Bertram T, Snijders C, Haji U, Patel PM, Geracioti TD, Chrousos GP, Baker DG. PMID: 30390522.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    9. Spinal Cord Stimulator Related Infections: Findings From a Multicenter Retrospective Analysis of 2737 Implants. Neuromodulation. 2017 Aug; 20(6):553-557. Bendel MA, O'Brien T, Hoelzer BC, Deer TR, Pittelkow TP, Costandi S, Walega DR, Azer G, Hayek SM, Wang Z, Eldrige JS, Qu W, Rosenow JM, Falowski SM, Neuman SA, Moeschler SM, Wassef C, Kim C, Niazi T, Saifullah T, Yee B, Kim C, Oryhan CL, Warren DT, Lerman I, Mora R, Hanes M, Simopoulos T, Sharma S, Gilligan C, Grace W, Ade T, Mekhail NA, Hunter JP, Choi D, Choi DY. PMID: 28726312.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCellsPHPublic Health
    10. Spinal Cord Stimulator Implant Infection Rates and Risk Factors: A Multicenter Retrospective Study. Neuromodulation. 2017 Aug; 20(6):558-562. Hoelzer BC, Bendel MA, Deer TR, Eldrige JS, Walega DR, Wang Z, Costandi S, Azer G, Qu W, Falowski SM, Neuman SA, Moeschler SM, Wassef C, Kim C, Niazi T, Saifullah T, Yee B, Kim C, Oryhan CL, Rosenow JM, Warren DT, Lerman I, Mora R, Hayek SM, Hanes M, Simopoulos T, Sharma S, Gilligan C, Grace W, Ade T, Mekhail NA, Hunter JP, Choi D, Choi DY. PMID: 28493599.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansPHPublic Health
    11. Posttraumatic stress disorder influences the nociceptive and intrathecal cytokine response to a painful stimulus in combat veterans. Psychoneuroendocrinology. 2016 11; 73:99-108. Lerman I, Davis BA, Bertram TM, Proudfoot J, Hauger RL, Coe CL, Patel PM, Baker DG. PMID: 27490714.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    12. Noninvasive Transcutaneous Vagus Nerve Stimulation Decreases Whole Blood Culture-Derived Cytokines and Chemokines: A Randomized, Blinded, Healthy Control Pilot Trial. Neuromodulation. 2016 Apr; 19(3):283-90. Lerman I, Hauger R, Sorkin L, Proudfoot J, Davis B, Huang A, Lam K, Simon B, Baker DG. PMID: 26990318.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCells
    13. Techniques in Regional Anesthesia and Pain Medicine. Optimizing needle tip visualization during out-of-plane ultrasonography: A novel technique. 2015; 4(18):123-125. Imanuel R.Lerman MD MS Dmitri Souzdalnitski MD PhD, Bryan A. Davis MD MS, Lei Shi MD PhD . View Publication.
    14. A Novel Freehand (Underhand), Out-of-Plane Ultrasound Technique to Optimize Visualization of Needle Tip During Subacromial Bursa Injection. Reg Anesth Pain Med. 2015 Nov-Dec; 40(6):730-1. Shi L, Souzdalnitski D, Lerman I. PMID: 26488082.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    15. Ultrasound-guided regional anesthesia simulation and trainee performance. Techniques in Regional Anesthesia and Pain Management. 2015; 18(4):110-118. Imanuel R. Lerman, MD, MS, Dmitri Souzdalnitski, MD, PhD, Thomas Halaszynski, DMD, MD, MBA, Feng Dai, PhD, Maged Guirguis, MD, Samer N. Narouze, MD, PhD, FIPP. View Publication.
    16. Novel High-Frequency Peripheral Nerve Stimulator Treatment of Refractory Postherpetic Neuralgia: A Brief Technical Note. Neuromodulation. 2015 Aug; 18(6):487-93; discussion 493. Lerman IR, Chen JL, Hiller D, Souzdalnitski D, Sheean G, Wallace M, Barba D. PMID: 25832898.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    17. A low-cost, durable, combined ultrasound and fluoroscopic phantom for cervical transforaminal injections. Reg Anesth Pain Med. 2012 May-Jun; 37(3):344-8. Lerman IR, Souzdalnitski D, Narouze S. PMID: 22476241.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    18. Genetic variability in forced and voluntary endurance exercise performance in seven inbred mouse strains. J Appl Physiol (1985). 2002 Jun; 92(6):2245-55. Lerman I, Harrison BC, Freeman K, Hewett TE, Allen DL, Robbins J, Leinwand LA. PMID: 12015333.
      View in: PubMed   Mentions: 93     Fields:    Translation:Animals
    19. Alterations in cardiac adrenergic signaling and calcium cycling differentially affect the progression of cardiomyopathy. J Clin Invest. 2001 Apr; 107(8):967-74. Freeman K, Lerman I, Kranias EG, Bohlmeyer T, Bristow MR, Lefkowitz RJ, Iaccarino G, Koch WJ, Leinwand LA. PMID: 11306600.
      View in: PubMed   Mentions: 48     Fields:    Translation:AnimalsCells
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