Linda Sorkin

Title(s)Emeritus Professor, Anesthesiology
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Collapse Research 
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    Targeting lipid rafts for treatment of migraine
    NIH R41NS113705Sep 30, 2019 - Aug 31, 2021
    Role: Co-Principal Investigator
    Spinal TNF elicits AMPAr trafficking and hyperalgesia
    NIH R01NS067459May 1, 2010 - Apr 30, 2016
    Role: Principal Investigator
    The Regulatory Role of Spinal Lipoxins in Nociception
    NIH R21DA021654May 1, 2007 - Apr 30, 2009
    Role: Principal Investigator
    Cytokine and MAP Kinase Involvement in Neuropathic Pain
    NIH R01NS048563Jan 15, 2005 - Dec 31, 2009
    Role: Principal Investigator
    Annual Meeting of the American Pain Society
    NIH U13NS043308Mar 5, 2002 - Aug 28, 2006
    Role: Principal Investigator
    Ca permeable non-NMDAr: New spinal sensitization pathway
    NIH R01NS041580Dec 15, 2001 - Nov 30, 2007
    Role: Principal Investigator
    ANTIBODY NOCICEPTOR SENSITIZATION &ALLOYDNIA
    NIH R01NS035630Apr 1, 1997 - Jan 31, 2002
    Role: Principal Investigator
    SPINAL MEDIATORS OF ARTHRITIS INDUCED HYPERALGESIA
    NIH R01AR042235Dec 29, 1994 - Nov 30, 1997
    Role: Principal Investigator
    AWAKE CAT SPINAL CORD CELLS DRUG AND BEHAVORIAL EFFECTS
    NIH F32NS007623Mar 25, 1986
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    1. Anti-GD2 induced allodynia in rats can be reduced by pretreatment with DFMO. PLoS One. 2020; 15(7):e0236115. Diccianni MB, Kempinska K, Gangoti JA, Yu AL, Sorkin LS. PMID: 32697811; PMCID: PMC7375533.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    2. Noninvasive vagus nerve stimulation alters neural response and physiological autonomic tone to noxious thermal challenge. PLoS One. 2019; 14(2):e0201212. Lerman I, Davis B, Huang M, Huang C, Sorkin L, Proudfoot J, Zhong E, Kimball D, Rao R, Simon B, Spadoni A, Strigo I, Baker DG, Simmons AN. PMID: 30759089; PMCID: PMC6373934.
      View in: PubMed   Mentions: 26     Fields:    Translation:Humans
    3. Origins of antidromic activity in sensory afferent fibers and neurogenic inflammation. Semin Immunopathol. 2018 May; 40(3):237-247. Sorkin LS, Eddinger KA, Woller SA, Yaksh TL. PMID: 29423889; PMCID: PMC7879713.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
    4. Inflammation-induced GluA1 trafficking and membrane insertion of Ca2+ permeable AMPA receptors in dorsal horn neurons is dependent on spinal tumor necrosis factor, PI3 kinase and protein kinase A. Exp Neurol. 2017 07; 293:144-158. Wigerblad G, Huie JR, Yin HZ, Leinders M, Pritchard RA, Koehrn FJ, Xiao WH, Bennett GJ, Huganir RL, Ferguson AR, Weiss JH, Svensson CI, Sorkin LS. PMID: 28412220; PMCID: PMC5539914.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    5. Increased miR-132-3p expression is associated with chronic neuropathic pain. Exp Neurol. 2016 09; 283(Pt A):276-86. Leinders M, Üçeyler N, Pritchard RA, Sommer C, Sorkin LS. PMID: 27349406; PMCID: PMC4992589.
      View in: PubMed   Mentions: 52     Fields:    Translation:HumansAnimalsCells
    6. Effects of intraplantar botulinum toxin-B on carrageenan-induced changes in nociception and spinal phosphorylation of GluA1 and Akt. Eur J Neurosci. 2016 07; 44(1):1714-22. Sikandar S, Gustavsson Y, Marino MJ, Dickenson AH, Yaksh TL, Sorkin LS, Ramachandran R. PMID: 27108664; PMCID: PMC4931962.
      View in: PubMed   Mentions: 3  Translation:AnimalsCells
    7. Noninvasive Transcutaneous Vagus Nerve Stimulation Decreases Whole Blood Culture-Derived Cytokines and Chemokines: A Randomized, Blinded, Healthy Control Pilot Trial. Neuromodulation. 2016 Apr; 19(3):283-90. Lerman I, Hauger R, Sorkin L, Proudfoot J, Davis B, Huang A, Lam K, Simon B, Baker DG. PMID: 26990318.
      View in: PubMed   Mentions: 82     Fields:    Translation:HumansCells
    8. Different phosphoinositide 3-kinase isoforms mediate carrageenan nociception and inflammation. Pain. 2016 Jan; 157(1):137-146. Pritchard RA, Falk L, Larsson M, Leinders M, Sorkin LS. PMID: 26313408; PMCID: PMC4711388.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    9. The search for novel analgesics: targets and mechanisms. F1000Prime Rep. 2015; 7:56. Yaksh TL, Woller SA, Ramachandran R, Sorkin LS. PMID: 26097729; PMCID: PMC4447049.
      View in: PubMed   Mentions: 45  
    10. Modulation of peripheral inflammation by the spinal cord. Handb Exp Pharmacol. 2015; 227:191-206. Sorkin LS. PMID: 25846620.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    11. Differential distribution of PI3K isoforms in spinal cord and dorsal root ganglia: potential roles in acute inflammatory pain. Pain. 2014 Jun; 155(6):1150-1160. Leinders M, Koehrn FJ, Bartok B, Boyle DL, Shubayev V, Kalcheva I, Yu NK, Park J, Kaang BK, Hefferan MP, Firestein GS, Sorkin LS. PMID: 24631588; PMCID: PMC4128246.
      View in: PubMed   Mentions: 17     Fields:    Translation:Animals
    12. Chimeric antibody c.8B6 to O-acetyl-GD2 mediates the same efficient anti-neuroblastoma effects as therapeutic ch14.18 antibody to GD2 without antibody induced allodynia. PLoS One. 2014; 9(2):e87210. Terme M, Dorvillius M, Cochonneau D, Chaumette T, Xiao W, Diccianni MB, Barbet J, Yu AL, Paris F, Sorkin LS, Birklé S. PMID: 24520328; PMCID: PMC3919714.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    13. TNF-α triggers rapid membrane insertion of Ca(2+) permeable AMPA receptors into adult motor neurons and enhances their susceptibility to slow excitotoxic injury. Exp Neurol. 2012 Dec; 238(2):93-102. Yin HZ, Hsu CI, Yu S, Rao SD, Sorkin LS, Weiss JH. PMID: 22921461; PMCID: PMC3498614.
      View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
    14. Carrageenan induced phosphorylation of Akt is dependent on neurokinin-1 expressing neurons in the superficial dorsal horn. Mol Pain. 2012 Jan 13; 8:4. Choi JI, Koehrn FJ, Sorkin LS. PMID: 22243518; PMCID: PMC3305429.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    15. A pilot study of the effects of cannabis on appetite hormones in HIV-infected adult men. Brain Res. 2012 Jan 11; 1431:46-52. Riggs PK, Vaida F, Rossi SS, Sorkin LS, Gouaux B, Grant I, Ellis RJ. PMID: 22133305; PMCID: PMC6200580.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansCTClinical Trials
    16. Molecular mechanism of cross-organ reflex sensitization: should I pay attention to it? Anesthesiology. 2011 Jan; 114(1):14-5. Zuo Z, Sorkin LS. PMID: 21150576.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    17. Peripheral inflammation induces tumor necrosis factor dependent AMPA receptor trafficking and Akt phosphorylation in spinal cord in addition to pain behavior. Pain. 2010 May; 149(2):243-253. Choi JI, Svensson CI, Koehrn FJ, Bhuskute A, Sorkin LS. PMID: 20202754; PMCID: PMC2860679.
      View in: PubMed   Mentions: 76     Fields:    
    18. Anti-GD(2) with an FC point mutation reduces complement fixation and decreases antibody-induced allodynia. Pain. 2010 Apr; 149(1):135-142. Sorkin LS, Otto M, Baldwin WM, Vail E, Gillies SD, Handgretinger R, Barfield RC, Yu HM, Yu AL. PMID: 20171010; PMCID: PMC3755890.
      View in: PubMed   Mentions: 84     Fields:    Translation:Animals
    19. Behavioral models of pain states evoked by physical injury to the peripheral nerve. Neurotherapeutics. 2009 Oct; 6(4):609-19. Sorkin LS, Yaksh TL. PMID: 19789066; PMCID: PMC5084283.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimals
    20. MKK3, an upstream activator of p38, contributes to formalin phase 2 and late allodynia in mice. Neuroscience. 2009 Aug 18; 162(2):462-71. Sorkin LS, Boyle DL, Hammaker D, Herman DS, Vail E, Firestein GS. PMID: 19427893; PMCID: PMC2802055.
      View in: PubMed   Mentions: 9     Fields:    
    21. Spinal p38 mitogen-activated protein kinase mediates allodynia induced by first-degree burn in the rat. J Neurosci Res. 2009 Mar; 87(4):948-55. Sorkin L, Svensson CI, Jones-Cordero TL, Hefferan MP, Campana WM. PMID: 18855936; PMCID: PMC2644733.
      View in: PubMed   Mentions: 13     Fields:    
    22. Selective stimulation of either tumor necrosis factor receptor differentially induces pain behavior in vivo and ectopic activity in sensory neurons in vitro. Neuroscience. 2008 Nov 19; 157(2):414-23. Schäfers M, Sommer C, Geis C, Hagenacker T, Vandenabeele P, Sorkin LS. PMID: 18838115.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
    23. Spinal p38 MAP kinase regulates peripheral cholinergic outflow. Arthritis Rheum. 2008 Sep; 58(9):2919-21. Waldburger JM, Boyle DL, Edgar M, Sorkin LS, Levine YA, Pavlov VA, Tracey K, Firestein GS. PMID: 18759350; PMCID: PMC4533855.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    24. The sensitization of a broad spectrum of sensory nerve fibers in a rat model of acute postoperative pain and its response to intrathecal pharmacotherapy. Pain. 2008 Oct 31; 139(3):569-577. Nagakura Y, Jones TL, Malkmus SA, Sorkin L, Yaksh TL. PMID: 18692315; PMCID: PMC3346272.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    25. Secondary hyperalgesia in the rat first degree burn model is independent of spinal cyclooxygenase and nitric oxide synthase. Eur J Pharmacol. 2008 Jun 10; 587(1-3):118-23. Sorkin LS, Doom CM, Maruyama KP, Nanigian DB. PMID: 18440503; PMCID: PMC2703817.
      View in: PubMed   Mentions: 2     Fields:    
    26. Effect of cytokines on neuronal excitability. Neurosci Lett. 2008 Jun 06; 437(3):188-93. Schäfers M, Sorkin L. PMID: 18420346.
      View in: PubMed   Mentions: 88     Fields:    Translation:AnimalsCells
    27. Secondary hyperalgesia in the postoperative pain model is dependent on spinal calcium/calmodulin-dependent protein kinase II alpha activation. Anesth Analg. 2007 Dec; 105(6):1650-6, table of contents. Jones TL, Lustig AC, Sorkin LS. PMID: 18042863.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    28. Low-speed subcellular fractionation method for determining noxious stimulus-evoked spinal neurokinin-1 receptor internalization. J Neurosci Methods. 2007 Mar 30; 161(1):23-31. Jones TL, Hefferan MP, Marsala M, Sorkin LS. PMID: 17083983.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    29. Regulation of peripheral inflammation by spinal p38 MAP kinase in rats. PLoS Med. 2006 Sep; 3(9):e338. Boyle DL, Jones TL, Hammaker D, Svensson CI, Rosengren S, Albani S, Sorkin L, Firestein GS. PMID: 16953659; PMCID: PMC1560929.
      View in: PubMed   Mentions: 42     Fields:    Translation:AnimalsCells
    30. [Spinal glutamate receptor antagonists differentiate primary and secondary mechanical hyperalgesia caused by incision]. Schmerz. 2006 Jun; 20(3):245-53. Pogatzki-Zahn EM, Niemeier JS, Sorkin LS, Brennan TJ. PMID: 16763860.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    31. Covariance among age, spinal p38 MAP kinase activation and allodynia. J Pain. 2006 May; 7(5):337-45. Svensson CI, Schäfers M, Jones TL, Yaksh TL, Sorkin LS. PMID: 16632323.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    32. Activated PKA and PKC, but not CaMKIIalpha, are required for AMPA/Kainate-mediated pain behavior in the thermal stimulus model. Pain. 2005 Oct; 117(3):259-270. Jones TL, Sorkin LS. PMID: 16150547.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    33. Hyperpolarization-activated, cation-nonselective, cyclic nucleotide-modulated channel blockade alleviates mechanical allodynia and suppresses ectopic discharge in spinal nerve ligated rats. J Pain. 2005 Jul; 6(7):417-24. Lee DH, Chang L, Sorkin LS, Chaplan SR. PMID: 15993819.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    34. Spinal blockade of TNF blocks spinal nerve ligation-induced increases in spinal P-p38. Neurosci Lett. 2005 May 13; 379(3):209-13. Svensson CI, Schäfers M, Jones TL, Powell H, Sorkin LS. PMID: 15843065.
      View in: PubMed   Mentions: 45     Fields:    Translation:AnimalsCells
    35. Calcium-permeable alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid/kainate receptors mediate development, but not maintenance, of secondary allodynia evoked by first-degree burn in the rat. J Pharmacol Exp Ther. 2004 Jul; 310(1):223-9. Jones TL, Sorkin LS. PMID: 15007101.
      View in: PubMed   Mentions: 17     Fields:    Translation:Animals
    36. Cyclooxygenase inhibition in nerve-injury- and TNF-induced hyperalgesia in the rat. Exp Neurol. 2004 Jan; 185(1):160-8. Schäfers M, Marziniak M, Sorkin LS, Yaksh TL, Sommer C. PMID: 14697327.
      View in: PubMed   Mentions: 32     Fields:    Translation:Animals
    37. Regulation of peripheral inflammation by spinal adenosine: role of somatic afferent fibers. Exp Neurol. 2003 Nov; 184(1):162-8. Sorkin LS, Moore J, Boyle DL, Yang L, Firestein GS. PMID: 14637089.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    38. Spinal glutamate receptor antagonists differentiate primary and secondary mechanical hyperalgesia caused by incision. Pain. 2003 Sep; 105(1-2):97-107. Pogatzki EM, Niemeier JS, Sorkin LS, Brennan TJ. PMID: 14499425.
      View in: PubMed   Mentions: 18     Fields:    Translation:Animals
    39. Spinal nerve ligation induces transient upregulation of tumor necrosis factor receptors 1 and 2 in injured and adjacent uninjured dorsal root ganglia in the rat. Neurosci Lett. 2003 Aug 28; 347(3):179-82. Schäfers M, Sorkin LS, Geis C, Shubayev VI. PMID: 12875915.
      View in: PubMed   Mentions: 43     Fields:    Translation:AnimalsCells
    40. Intramuscular injection of tumor necrosis factor-alpha induces muscle hyperalgesia in rats. Pain. 2003 Aug; 104(3):579-588. Schäfers M, Sorkin LS, Sommer C. PMID: 12927630.
      View in: PubMed   Mentions: 40     Fields:    Translation:Animals
    41. Spinal adenosine agonist reduces c-fos and astrocyte activation in dorsal horn of rats with adjuvant-induced arthritis. Neurosci Lett. 2003 Apr 10; 340(2):119-22. Sorkin LS, Maruyama K, Boyle DL, Yang L, Marsala M, Firestein GS. PMID: 12668251.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    42. Tumor necrosis factor-alpha induces mechanical allodynia after spinal nerve ligation by activation of p38 MAPK in primary sensory neurons. J Neurosci. 2003 Apr 01; 23(7):2517-21. Schäfers M, Svensson CI, Sommer C, Sorkin LS. PMID: 12684435; PMCID: PMC6742090.
      View in: PubMed   Mentions: 171     Fields:    Translation:AnimalsCells
    43. Increased sensitivity of injured and adjacent uninjured rat primary sensory neurons to exogenous tumor necrosis factor-alpha after spinal nerve ligation. J Neurosci. 2003 Apr 01; 23(7):3028-38. Schäfers M, Lee DH, Brors D, Yaksh TL, Sorkin LS. PMID: 12684490; PMCID: PMC6742101.
      View in: PubMed   Mentions: 91     Fields:    Translation:AnimalsCells
    44. Effects of full-thickness burns on nociceptor sensitization in anesthetized rats. Burns. 2002 Dec; 28(8):772-7. Junger H, Moore AC, Sorkin LS. PMID: 12464476.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    45. Spinal adenosine receptor activation inhibits inflammation and joint destruction in rat adjuvant-induced arthritis. Arthritis Rheum. 2002 Nov; 46(11):3076-82. Boyle DL, Moore J, Yang L, Sorkin LS, Firestein GS. PMID: 12428252.
      View in: PubMed   Mentions: 13     Fields:    Translation:Animals
    46. Antibody directed against GD(2) produces mechanical allodynia, but not thermal hyperalgesia when administered systemically or intrathecally despite its dependence on capsaicin sensitive afferents. Brain Res. 2002 Mar 15; 930(1-2):67-74. Sorkin LS, Yu AL, Junger H, Doom CM. PMID: 11879797.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    47. Pain models display differential sensitivity to Ca2+-permeable non-NMDA glutamate receptor antagonists. Anesthesiology. 2001 Oct; 95(4):965-73. Sorkin LS, Yaksh TL, Doom CM. PMID: 11605940.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    48. Upregulation of dorsal root ganglion (alpha)2(delta) calcium channel subunit and its correlation with allodynia in spinal nerve-injured rats. J Neurosci. 2001 Mar 15; 21(6):1868-75. Luo ZD, Chaplan SR, Higuera ES, Sorkin LS, Stauderman KA, Williams ME, Yaksh TL. PMID: 11245671; PMCID: PMC6762626.
      View in: PubMed   Mentions: 173     Fields:    Translation:AnimalsCells
    49. Antibody activation and immune reactions: potential linkage to pain and neuropathy. Pain Med. 2000 Dec; 1(4):296-302. Sorkin LS. PMID: 15101875.
      View in: PubMed   Mentions: 2     Fields:    
    50. Isoprostanes induce plasma extravasation in rat skin. Prostaglandins Other Lipid Mediat. 2000 Oct; 62(4):335-42. Junger H, Sorkin LS. PMID: 11060897.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    51. C-nociceptor sensitization by isoprostanes is cyclooxygenase dependent. Brain Res. 2000 Jun 09; 867(1-2):255-8. Junger H, Sorkin LS. PMID: 10837823.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    52. Isoprostanes, novel eicosanoids that produce nociception and sensitize rat sensory neurons. J Pharmacol Exp Ther. 2000 Jun; 293(3):912-20. Evans AR, Junger H, Southall MD, Nicol GD, Sorkin LS, Broome JT, Bailey TW, Vasko MR. PMID: 10869392.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    53. Epineurial application of TNF elicits an acute mechanical hyperalgesia in the awake rat. J Peripher Nerv Syst. 2000 Jun; 5(2):96-100. Sorkin LS, Doom CM. PMID: 10905468.
      View in: PubMed   Mentions: 58     Fields:    Translation:Animals
    54. Nociceptive and inflammatory effects of subcutaneous TNFalpha. Pain. 2000 Mar; 85(1-2):145-51. Junger H, Sorkin LS. PMID: 10692613.
      View in: PubMed   Mentions: 71     Fields:    Translation:AnimalsCells
    55. Mechanical allodynia in rats is blocked by a Ca2+ permeable AMPA receptor antagonist. Neuroreport. 1999 Nov 26; 10(17):3523-6. Sorkin LS, Yaksh TL, Doom CM. PMID: 10619637.
      View in: PubMed   Mentions: 18     Fields:    Translation:Animals
    56. Acute pain mechanisms. Surg Clin North Am. 1999 Apr; 79(2):213-29. Sorkin LS, Wallace MS. PMID: 10352652.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    57. Systemic gabapentin and S(+)-3-isobutyl-gamma-aminobutyric acid block secondary hyperalgesia. Brain Res. 1998 Nov 09; 810(1-2):93-9. Jones DL, Sorkin LS. PMID: 9813259.
      View in: PubMed   Mentions: 16     Fields:    Translation:Animals
    58. Spinal bicuculline produces hypersensitivity of dorsal horn neurons: effects of excitatory amino acid antagonists. Pain. 1998 Aug; 77(2):181-190. Sorkin LS, Puig S, Jones DL. PMID: 9766836.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    59. Gabapentin reverses the allodynia produced by the administration of anti-GD2 ganglioside, an immunotherapeutic drug. Anesth Analg. 1998 Jan; 86(1):111-6. Gillin S, Sorkin LS. PMID: 9428862.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    60. Tumour necrosis factor-alpha induces ectopic activity in nociceptive primary afferent fibres. Neuroscience. 1997 Nov; 81(1):255-62. Sorkin LS, Xiao WH, Wagner R, Myers RR. PMID: 9300418.
      View in: PubMed   Mentions: 109     Fields:    Translation:AnimalsCells
    61. Intravenous lidocaine: effects on controlling pain after anti-GD2 antibody therapy in children with neuroblastoma--a report of a series. Anesth Analg. 1997 Oct; 85(4):794-6. Wallace MS, Lee J, Sorkin L, Dunn JS, Yaksh T, Yu A. PMID: 9322457.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    62. An animal model of pain produced by systemic administration of an immunotherapeutic anti-ganglioside antibody. Pain. 1997 Jan; 69(1-2):119-25. Slart R, Yu AL, Yaksh TL, Sorkin LS. PMID: 9060021.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimals
    63. Electrophysiological characteristics of primary afferent fibers after systemic administration of anti-GD2 ganglioside antibody. Pain. 1997 Jan; 69(1-2):145-51. Xiao WH, Yu AL, Sorkin LS. PMID: 9060025.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    64. Neuronal model of tactile allodynia produced by spinal strychnine: effects of excitatory amino acid receptor antagonists and a mu-opiate receptor agonist. Pain. 1996 Dec; 68(2-3):283-92. Sorkin LS, Puig S. PMID: 9121816.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    65. Evoked Release of Amino Acids and Prostanoids in Spinal Cords of Anesthetized Rats: Changes During Peripheral Inflammation and Hyperalgesia. Am J Ther. 1996 Apr; 3(4):268-275. Sorkin LS, Moore JH. PMID: 11862260.
      View in: PubMed   Mentions: 1     Fields:    
    66. Formalin-evoked activity in identified primary afferent fibers: systemic lidocaine suppresses phase-2 activity. Pain. 1996 Feb; 64(2):345-355. Puig S, Sorkin LS. PMID: 8740613.
      View in: PubMed   Mentions: 91     Fields:    Translation:AnimalsCells
    67. Transient spinal ischemia in rat: characterization of spinal cord blood flow, extracellular amino acid release, and concurrent histopathological damage. J Cereb Blood Flow Metab. 1994 Jul; 14(4):604-14. Marsala M, Sorkin LS, Yaksh TL. PMID: 8014207.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    68. Radicular artery blood flow does not redistribute fentanyl from the epidural space to the spinal cord. Anesthesiology. 1994 Apr; 80(4):872-8. Bernards CM, Sorkin LS. PMID: 8024142.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    69. Raphe magnus stimulation-induced antinociception in the cat is associated with release of amino acids as well as serotonin in the lumbar dorsal horn. Brain Res. 1993 Jul 30; 618(1):95-108. Sorkin LS, McAdoo DJ, Willis WD. PMID: 8402183.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    70. NMDA evokes an L-NAME sensitive spinal release of glutamate and citrulline. Neuroreport. 1993 May; 4(5):479-82. Sorkin LS. PMID: 8099815.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    71. Amino acids and serotonin are released into the lumbar spinal cord of the anesthetized cat following intradermal capsaicin injections. Brain Res. 1993 Apr 02; 607(1-2):89-98. Sorkin LS, McAdoo DJ. PMID: 7683245.
      View in: PubMed   Mentions: 16     Fields:    Translation:Animals
    72. The role of NMDA and non-NMDA excitatory amino acid receptors in the excitation of primate spinothalamic tract neurons by mechanical, chemical, thermal, and electrical stimuli. J Neurosci. 1992 Aug; 12(8):3025-41. Dougherty PM, Palecek J, Paleckova V, Sorkin LS, Willis WD. PMID: 1353793; PMCID: PMC6575659.
      View in: PubMed   Mentions: 40     Fields:    Translation:AnimalsCells
    73. Stimulation in the ventral posterior lateral nucleus of the primate thalamus leads to release of serotonin in the lumbar spinal cord. Brain Res. 1992 May 29; 581(2):307-10. Sorkin LS, McAdoo DJ, Willis WD. PMID: 1393535.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    74. The effects of A- and C-fiber stimulation on patterns of neuropeptide immunostaining in the rat superficial dorsal horn. Brain Res. 1992 May 15; 580(1-2):121-8. Klein CM, Coggeshall RE, Carlton SM, Sorkin LS. PMID: 1504792.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    75. Neural changes in acute arthritis in monkeys. II. Increased glutamate immunoreactivity in the medial articular nerve. Brain Res Brain Res Rev. 1992 Jan-Apr; 17(1):15-27. Westlund KN, Sun YC, Sluka KA, Dougherty PM, Sorkin LS, Willis WD. PMID: 1353392.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    76. Neural changes in acute arthritis in monkeys. IV. Time-course of amino acid release into the lumbar dorsal horn. Brain Res Brain Res Rev. 1992 Jan-Apr; 17(1):39-50. Sorkin LS, Westlund KN, Sluka KA, Dougherty PM, Willis WD. PMID: 1638274.
      View in: PubMed   Mentions: 14     Fields:    Translation:Animals
    77. Neural changes in acute arthritis in monkeys. III. Changes in substance P, calcitonin gene-related peptide and glutamate in the dorsal horn of the spinal cord. Brain Res Brain Res Rev. 1992 Jan-Apr; 17(1):29-38. Sluka KA, Dougherty PM, Sorkin LS, Willis WD, Westlund KN. PMID: 1379098.
      View in: PubMed   Mentions: 11     Fields:    Translation:Animals
    78. Neural changes in acute arthritis in monkeys. I. Parallel enhancement of responses of spinothalamic tract neurons to mechanical stimulation and excitatory amino acids. Brain Res Brain Res Rev. 1992 Jan-Apr; 17(1):1-13. Dougherty PM, Sluka KA, Sorkin LS, Westlund KN, Willis WD. PMID: 1638273.
      View in: PubMed   Mentions: 15     Fields:    Translation:Animals
    79. Unmyelinated primary afferent fiber stimulation depletes dynorphin A (1-8) immunoreactivity in rat ventral horn. Brain Res. 1991 Dec 06; 566(1-2):70-6. Klein CM, Sorkin LS, Chung K, Coggeshall RE. PMID: 1687665.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    80. Neurogenic hyperalgesia: central neural correlates in responses of spinothalamic tract neurons. J Neurophysiol. 1991 Jul; 66(1):228-46. Simone DA, Sorkin LS, Oh U, Chung JM, Owens C, LaMotte RH, Willis WD. PMID: 1919669.
      View in: PubMed   Mentions: 82     Fields:    Translation:HumansAnimalsCells
    81. Release and metabolism of 5-hydroxytryptamine in the cat spinal cord examined with microdialysis. J Pharmacol Exp Ther. 1991 Apr; 257(1):192-9. Sorkin LS, Hughes MG, Liu D, Willis WD, McAdoo DJ. PMID: 1708424.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    82. Enhancement of somatosensory evoked potentials by etomidate in cats: an investigation of its site of action. Anesthesiology. 1991 Mar; 74(3):499-503. Samra SK, Sorkin LS. PMID: 2001029.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    83. Changes in calcitonin gene-related peptide immunoreactivity in the rat dorsal horn following electrical stimulation of the sciatic nerve. Neurosci Lett. 1990 Jul 31; 115(2-3):149-54. Klein CM, Coggeshall RE, Carlton SM, Westlund KN, Sorkin LS. PMID: 2234494.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    84. Convergence of heterotopic nociceptive information onto neurons of caudal medullary reticular formation in monkey (Macaca fascicularis). J Neurophysiol. 1990 May; 63(5):1118-27. Villanueva L, Cliffer KD, Sorkin LS, Le Bars D, Willis WD. PMID: 2358866.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    85. Calcitonin gene-related peptide containing primary afferent fibers synapse on primate spinothalamic tract cells. Neurosci Lett. 1990 Feb 05; 109(1-2):76-81. Carlton SM, Westlund KN, Zhang DX, Sorkin LS, Willis WD. PMID: 2314643.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    86. Norepinephrine and serotonin release upon impact injury to rat spinal cord. J Neurotrauma. 1990; 7(4):219-27. Liu DX, Valadez V, Sorkin LS, McAdoo DJ. PMID: 1707100.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    87. The primate spinocervicothalamic pathway: responses of cells of the lateral cervical nucleus and spinocervical tract to innocuous and noxious stimuli. J Neurophysiol. 1988 Mar; 59(3):861-85. Downie JW, Ferrington DG, Sorkin LS, Willis WD. PMID: 3367201.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    88. Microdialysis recovery of serotonin released in spinal cord dorsal horn. J Neurosci Methods. 1988 Mar; 23(2):131-8. Sorkin LS, Steinman JL, Hughes MG, Willis WD, McAdoo DJ. PMID: 2451773.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    89. Physiological identification of afferent fibers and postsynaptic sensory neurons in the spinal cord of the intact, awake cat. Exp Neurol. 1988 Feb; 99(2):412-27. Sorkin LS, Morrow TJ, Casey KL. PMID: 3338532.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    90. Response properties of spinal neurons projecting to midbrain or midbrain-thalamus in the monkey. Brain Res. 1987 Dec 22; 437(1):165-70. Yezierski RP, Sorkin LS, Willis WD. PMID: 2827865.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    91. Responses of spinothalamic tract cells in the superficial dorsal horn of the primate lumbar spinal cord. J Physiol. 1987 Jul; 388:681-703. Ferrington DG, Sorkin LS, Willis WD. PMID: 3656204; PMCID: PMC1192572.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    92. Response characteristics of neurons in the ventral posterior lateral nucleus of the monkey thalamus. J Neurophysiol. 1986 Aug; 56(2):370-90. Chung JM, Lee KH, Surmeier DJ, Sorkin LS, Kim J, Willis WD. PMID: 3760926.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    93. Classification of primate spinothalamic and somatosensory thalamic neurons based on cluster analysis. J Neurophysiol. 1986 Aug; 56(2):308-27. Chung JM, Surmeier DJ, Lee KH, Sorkin LS, Honda CN, Tsong Y, Willis WD. PMID: 3760923.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    94. Somatotopic organization and response characteristics of dorsal horn neurons in the cervical spinal cord of the cat. Somatosens Res. 1986; 3(4):323-38. Sorkin LS, Ferrington DG, Willis WD. PMID: 3775153.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    95. Responses of spinothalamic tract cells in the cat cervical spinal cord to innocuous and graded noxious stimuli. Somatosens Res. 1986; 3(4):339-58. Ferrington DG, Sorkin LS, Willis WD. PMID: 3775154.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
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