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Immo Scheffler

Title(s)Emeritus Professor, Molecular Biology
SchoolVc-academic Affairs
Address9500 Gilman Drive #0322
La Jolla CA 92093
Phone8/5-34--2741
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    MOLEC GENETICS OF COMPLEX I IN MAMMALIAN MITOCHONDRIA
    NIH/NIGMS R01GM059909Jul 1, 2001 - Jun 30, 2005
    Role: Principal Investigator
    MOLECULAR GENETICS OF RESPIRATION-DEFICIENT CELLS
    NIH/NIGMS R01GM033752Aug 1, 1984 - Mar 31, 1996
    Role: Principal Investigator
    MOLECULAR CHARACTERIZATION OF A HUMAN CENTROMERE
    NIH/NIGMS R01GM018835Sep 1, 1977 - Aug 31, 1993
    Role: Principal Investigator
    Cell and Molecular Genetics Training Program
    NIH/NIGMS T32GM007240Jul 1, 1975 - Jun 30, 2020
    Role: Co-Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Correction for Fogal et al., "Mitochondrial p32 Protein Is a Critical Regulator of Tumor Metabolism via Maintenance of Oxidative Phosphorylation". Mol Cell Biol. 2017 07 15; 37(14). Fogal V, Richardson AD, Karmali PP, Scheffler IE, Smith JW, Ruoslahti E. PMID: 28663271.
      View in: PubMed   Mentions:    Fields:    
    2. High throughput gene complementation screening permits identification of a mammalian mitochondrial protein synthesis (?(-)) mutant. Biochim Biophys Acta. 2016 Aug; 1857(8):1336-1343. Potluri P, Procaccio V, Scheffler IE, Wallace DC. PMID: 26946086.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    3. Mitochondrial disease associated with complex I (NADH-CoQ oxidoreductase) deficiency. J Inherit Metab Dis. 2015 May; 38(3):405-15. Scheffler IE. PMID: 25224827.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    4. PKCe promotes oncogenic functions of ATF2 in the nucleus while blocking its apoptotic function at mitochondria. Cell. 2012 Feb 03; 148(3):543-55. Lau E, Kluger H, Varsano T, Lee K, Scheffler I, Rimm DL, Ideker T, Ronai ZA. PMID: 22304920.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCells
    5. Mitochondrial dysfunction impairs tumor suppressor p53 expression/function. J Biol Chem. 2011 Jun 10; 286(23):20297-312. Compton S, Kim C, Griner NB, Potluri P, Scheffler IE, Sen S, Jerry DJ, Schneider S, Yadava N. PMID: 21502317.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    6. Assembling complex I with ACAD9. Cell Metab. 2010 Sep 08; 12(3):211-2. Scheffler IE. PMID: 20816087.
      View in: PubMed   Mentions: 1     Fields:    
    7. Mitochondrial p32 protein is a critical regulator of tumor metabolism via maintenance of oxidative phosphorylation. Mol Cell Biol. 2010 Mar; 30(6):1303-18. Fogal V, Richardson AD, Karmali PP, Scheffler IE, Smith JW, Ruoslahti E. PMID: 20100866.
      View in: PubMed   Mentions: 96     Fields:    Translation:HumansAnimalsCells
    8. Suppression of tumor growth in vivo by the mitocan alpha-tocopheryl succinate requires respiratory complex II. Clin Cancer Res. 2009 Mar 01; 15(5):1593-600. Dong LF, Freeman R, Liu J, Zobalova R, Marin-Hernandez A, Stantic M, Rohlena J, Valis K, Rodriguez-Enriquez S, Butcher B, Goodwin J, Brunk UT, Witting PK, Moreno-Sanchez R, Scheffler IE, Ralph SJ, Neuzil J. PMID: 19223492.
      View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
    9. A novel NDUFA1 mutation leads to a progressive mitochondrial complex I-specific neurodegenerative disease. Mol Genet Metab. 2009 Apr; 96(4):189-95. Potluri P, Davila A, Ruiz-Pesini E, Mishmar D, O'Hearn S, Hancock S, Simon M, Scheffler IE, Wallace DC, Procaccio V. PMID: 19185523.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    10. Alpha-tocopheryl succinate induces apoptosis by targeting ubiquinone-binding sites in mitochondrial respiratory complex II. Oncogene. 2008 Jul 17; 27(31):4324-35. Dong LF, Low P, Dyason JC, Wang XF, Prochazka L, Witting PK, Freeman R, Swettenham E, Valis K, Liu J, Zobalova R, Turanek J, Spitz DR, Domann FE, Scheffler IE, Ralph SJ, Neuzil J. PMID: 18372923.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansAnimalsCells
    11. Investigations of the potential effects of phosphorylation of the MWFE and ESSS subunits on complex I activity and assembly. Int J Biochem Cell Biol. 2008; 40(3):447-60. Yadava N, Potluri P, Scheffler IE. PMID: 17931954.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    12. Nuclear receptor ERR alpha and coactivator PGC-1 beta are effectors of IFN-gamma-induced host defense. Genes Dev. 2007 Aug 01; 21(15):1909-20. Sonoda J, Laganière J, Mehl IR, Barish GD, Chong LW, Li X, Scheffler IE, Mock DC, Bataille AR, Robert F, Lee CH, Giguère V, Evans RM. PMID: 17671090.
      View in: PubMed   Mentions: 73     Fields:    Translation:AnimalsCells
    13. Mitocans as anti-cancer agents targeting mitochondria: lessons from studies with vitamin E analogues, inhibitors of complex II. J Bioenerg Biomembr. 2007 Feb; 39(1):65-72. Neuzil J, Dyason JC, Freeman R, Dong LF, Prochazka L, Wang XF, Scheffler I, Ralph SJ. PMID: 17294131.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    14. Cyanide detoxification by the cobalamin precursor cobinamide. Exp Biol Med (Maywood). 2006 May; 231(5):641-9. Broderick KE, Potluri P, Zhuang S, Scheffler IE, Sharma VS, Pilz RB, Boss GR. PMID: 16636313.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    15. Molecular genetics of complex I-deficient Chinese hamster cell lines. Biochim Biophys Acta. 2004 Dec 06; 1659(2-3):160-71. Scheffler IE, Yadava N, Potluri P. PMID: 15576048.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    16. The role of the ESSS protein in the assembly of a functional and stable mammalian mitochondrial complex I (NADH-ubiquinone oxidoreductase). Eur J Biochem. 2004 Aug; 271(15):3265-73. Potluri P, Yadava N, Scheffler IE. PMID: 15265046.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    17. Disruption of mitochondrial function during apoptosis is mediated by caspase cleavage of the p75 subunit of complex I of the electron transport chain. Cell. 2004 Jun 11; 117(6):773-86. Ricci JE, Muñoz-Pinedo C, Fitzgerald P, Bailly-Maitre B, Perkins GA, Yadava N, Scheffler IE, Ellisman MH, Green DR. PMID: 15186778.
      View in: PubMed   Mentions: 156     Fields:    Translation:HumansAnimalsCells
    18. Import and orientation of the MWFE protein in mitochondrial NADH-ubiquinone oxidoreductase. Mitochondrion. 2004 Jun; 4(1):1-12. Yadava N, Scheffler IE. PMID: 16120368.
      View in: PubMed   Mentions: 2     Fields:    
    19. Development and characterization of a conditional mitochondrial complex I assembly system. J Biol Chem. 2004 Mar 26; 279(13):12406-13. Yadava N, Houchens T, Potluri P, Scheffler IE. PMID: 14722084.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    20. The tumor suppressor cybL, a component of the respiratory chain, mediates apoptosis induction. Mol Biol Cell. 2003 Aug; 14(8):3082-96. Albayrak T, Scherhammer V, Schoenfeld N, Braziulis E, Mund T, Bauer MK, Scheffler IE, Grimm S. PMID: 12925748.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    21. The role of the 5' untranslated region (UTR) in glucose-dependent mRNA decay. Yeast. 2002 Jul; 19(10):887-902. de la Cruz BJ, Prieto S, Scheffler IE. PMID: 12112242.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    22. Species-specific and mutant MWFE proteins. Their effect on the assembly of a functional mammalian mitochondrial complex I. J Biol Chem. 2002 Jun 14; 277(24):21221-30. Yadava N, Potluri P, Smith EN, Bisevac A, Scheffler IE. PMID: 11937507.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    23. Mitochondria make a come back. Adv Drug Deliv Rev. 2001 Jul 02; 49(1-2):3-26. Scheffler IE. PMID: 11377800.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    24. Molecular genetics of the mammalian NADH-ubiquinone oxidoreductase. J Bioenerg Biomembr. 2001 Jun; 33(3):243-50. Scheffler IE, Yadava N. PMID: 11695834.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    25. A century of mitochondrial research: achievements and perspectives. Mitochondrion. 2001 Jun; 1(1):3-31. Scheffler IE. PMID: 16120266.
      View in: PubMed   Mentions: 51     Fields:    
    26. Combined and individual mitochondrial HSP60 and HSP10 expression in cardiac myocytes protects mitochondrial function and prevents apoptotic cell deaths induced by simulated ischemia-reoxygenation. Circulation. 2001 Apr 03; 103(13):1787-92. Lin KM, Lin B, Lian IY, Mestril R, Scheffler IE, Dillmann WH. PMID: 11282911.
      View in: PubMed   Mentions: 50     Fields:    Translation:AnimalsCells
    27. Glucose-regulated turnover of mRNA and the influence of poly(A) tail length on half-life. J Biol Chem. 2000 May 12; 275(19):14155-66. Prieto S, de la Cruz BJ, Scheffler IE. PMID: 10799492.
      View in: PubMed   Mentions: 11     Fields:    Translation:Cells
    28. The NDUFA1 gene product (MWFE protein) is essential for activity of complex I in mammalian mitochondria. Proc Natl Acad Sci U S A. 1999 Apr 13; 96(8):4354-9. Au HC, Seo BB, Matsuno-Yagi A, Yagi T, Scheffler IE. PMID: 10200266.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    29. Targeted integration of a dominant neo(R) marker into a 2- to 3-Mb human minichromosome and transfer between cells. Cytogenet Cell Genet. 1999; 86(3-4):194-203. Au HC, Mascarello JT, Scheffler IE. PMID: 10575205.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    30. Control of mRNA turnover as a mechanism of glucose repression in Saccharomyces cerevisiae. Int J Biochem Cell Biol. 1998 Nov; 30(11):1175-93. Scheffler IE, de la Cruz BJ, Prieto S. PMID: 9839444.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    31. Molecular remedy of complex I defects: rotenone-insensitive internal NADH-quinone oxidoreductase of Saccharomyces cerevisiae mitochondria restores the NADH oxidase activity of complex I-deficient mammalian cells. Proc Natl Acad Sci U S A. 1998 Aug 04; 95(16):9167-71. Seo BB, Kitajima-Ihara T, Chan EK, Scheffler IE, Matsuno-Yagi A, Yagi T. PMID: 9689052.
      View in: PubMed   Mentions: 59     Fields:    Translation:AnimalsCells
    32. Characterization of the human SDHC gene encoding of the integral membrane proteins of succinate-quinone oxidoreductase in mitochondria. Gene. 1998 Jun 15; 213(1-2):133-40. Elbehti-Green A, Au HC, Mascarello JT, Ream-Robinson D, Scheffler IE. PMID: 9714607.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    33. Promoter analysis of the human succinate dehydrogenase iron-protein gene--both nuclear respiratory factors NRF-1 and NRF-2 are required. Eur J Biochem. 1998 Jan 15; 251(1-2):164-74. Au HC, Scheffler IE. PMID: 9492280.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    34. Molecular genetics of succinate:quinone oxidoreductase in eukaryotes. Prog Nucleic Acid Res Mol Biol. 1998; 60:267-315. Scheffler IE. PMID: 9594577.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    35. Co-operation of the 5' and 3' untranslated regions of ornithine decarboxylase mRNA and inhibitory role of its 3' untranslated region in regulating the translational efficiency of hybrid RNA species via cellular factor. Biochem J. 1997 Sep 01; 326 ( Pt 2):361-7. Lorenzini EC, Scheffler IE. PMID: 9291106.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    36. A respiration-deficient Chinese hamster cell line with a defect in mitochondrial protein synthesis: rapid turnover of some mitochondrial transcripts. Somat Cell Mol Genet. 1997 Jan; 23(1):27-35. Au HC, Scheffler IE. PMID: 9217999.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    37. Genetic analysis of glucose regulation in saccharomyces cerevisiae: control of transcription versus mRNA turnover. EMBO J. 1996 Jan 15; 15(2):363-74. Cereghino GP, Scheffler IE. PMID: 8617211.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    38. A Chinese hamster mutant cell line with a defect in the integral membrane protein CII-3 of complex II of the mitochondrial electron transport chain. J Biol Chem. 1995 Nov 03; 270(44):26104-8. Oostveen FG, Au HC, Meijer PJ, Scheffler IE. PMID: 7592812.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    39. Glucose-dependent turnover of the mRNAs encoding succinate dehydrogenase peptides in Saccharomyces cerevisiae: sequence elements in the 5' untranslated region of the Ip mRNA play a dominant role. Mol Biol Cell. 1995 Sep; 6(9):1125-43. Cereghino GP, Atencio DP, Saghbini M, Beiner J, Scheffler IE. PMID: 8534911.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    40. Structural organization of the gene encoding the human iron-sulfur subunit of succinate dehydrogenase. Gene. 1995 Jul 04; 159(2):249-53. Au HC, Ream-Robinson D, Bellew LA, Broomfield PL, Saghbini M, Scheffler IE. PMID: 7622059.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    41. Regulation of mammalian ornithine decarboxylase. Studies on the induction of the enzyme by hypotonic stress. Eur J Biochem. 1995 Jul 01; 231(1):40-4. Lövkvist-Wallström E, Stjernborg-Ulvsbäck L, Scheffler IE, Persson L. PMID: 7628482.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    42. Isolation and characterization of HL-60 cells resistant to nitroprusside-induced differentiation. J Biol Chem. 1994 Dec 23; 269(51):32155-61. Pilz RB, Berjis M, Idriss SD, Scheele JS, Suhasini M, Gao L, Scheffler IE, Boss GR. PMID: 7798212.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    43. Characterization of the gene encoding the iron-sulfur protein subunit of succinate dehydrogenase from Drosophila melanogaster. Gene. 1994 Nov 18; 149(2):261-5. Au HC, Scheffler IE. PMID: 7958999.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    44. Studies on the assembly of complex II in yeast mitochondria using chimeric human/yeast genes for the iron-sulfur protein subunit. Biochemistry. 1994 Jan 11; 33(1):159-65. Saghbini M, Broomfield PL, Scheffler IE. PMID: 8286334.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    45. The gene for the iron sulfur protein of succinate dehydrogenase (SDH-IP) maps to human chromosome 1p35-36.1. Somat Cell Mol Genet. 1993 Sep; 19(5):505-11. Leckschat S, Ream-Robinson D, Scheffler IE. PMID: 8291026.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    46. The C-terminus of the succinate dehydrogenase IP peptide of Saccharomyces cerevisiae is significant for assembly of complex II. Biochemistry. 1992 Sep 15; 31(36):8442-8. Schmidt DM, Saghbini M, Scheffler IE. PMID: 1390628.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    47. Control of mRNA turnover as a mechanism of glucose repression in Saccharomyces cerevisiae. Mol Cell Biol. 1992 Jul; 12(7):2941-8. Lombardo A, Cereghino GP, Scheffler IE. PMID: 1620107.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    48. The 5'- and 3'-untranslated regions of ornithine decarboxylase mRNA affect the translational efficiency. J Biol Chem. 1990 Jul 15; 265(20):11810-6. Grens A, Scheffler IE. PMID: 2365700.
      View in: PubMed   Mentions: 41     Fields:    Translation:AnimalsCells
    49. Cloning and characterization of the iron-sulfur subunit gene of succinate dehydrogenase from Saccharomyces cerevisiae. J Biol Chem. 1990 Jun 25; 265(18):10419-23. Lombardo A, Carine K, Scheffler IE. PMID: 2191948.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    50. Molecular and genetic characterization of an ornithine decarboxylase-deficient Chinese hamster cell line. J Biol Chem. 1990 May 25; 265(15):8880-6. Pilz RB, Steglich C, Scheffler IE. PMID: 1692838.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    51. Nucleotide sequence of the Chinese hamster ornithine decarboxylase gene. Nucleic Acids Res. 1989 Dec 25; 17(24):10497. Grens A, Steglich C, Pilz R, Scheffler IE. PMID: 2602162.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    52. Isolation and characterization of a Saccharomyces cerevisiae mutant with a disrupted gene for the IP subunit of succinate dehydrogenase. J Biol Chem. 1989 Nov 15; 264(32):18874-7. Lombardo A, Scheffler IE. PMID: 2681203.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    53. Molecular characterization of human minichromosomes with centromere from chromosome 1 in human-hamster hybrid cells. Somat Cell Mol Genet. 1989 Sep; 15(5):445-60. Carine K, Jacquemin-Sablon A, Waltzer E, Mascarello J, Scheffler IE. PMID: 2781415.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    54. Use of the DNA polymerase chain reaction for homology probing: isolation of partial cDNA or genomic clones encoding the iron-sulfur protein of succinate dehydrogenase from several species. Proc Natl Acad Sci U S A. 1989 Mar; 86(6):1934-8. Gould SJ, Subramani S, Scheffler IE. PMID: 2494655.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansAnimalsCells
    55. Molecular characterization of human minichromosomes in Chinese hamster/human somatic cell hybrids. Prog Clin Biol Res. 1989; 318:19-31. Scheffler IE, Carine K. PMID: 2576309.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    56. Steady-state and nuclear run-on analyses of transcription in a temperature-sensitive Chinese hamster cell mutant with a defect in RNA metabolism. Somat Cell Mol Genet. 1988 Sep; 14(5):439-59. Slezynger TC, Scheffler IE. PMID: 2459782.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    57. Temperature-sensitive Chinese hamster cell mutant with a defect in glycoprotein synthesis: accumulation of the EGF receptor in the endoplasmic reticulum and the role of the glucose-regulated protein GRP78. J Cell Physiol. 1988 Jul; 136(1):33-42. Feige JJ, Keller GA, Scheffler IE. PMID: 3294237.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    58. Characterization of single-copy probe from vicinity of centromere of human chromosome 1. Somat Cell Mol Genet. 1988 Jul; 14(4):381-91. Solus J, Jacquemin-Sablon A, Carine K, Waltzer E, Scheffler IE. PMID: 2840744.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    59. Analysis of the protein glycosylation defect of a temperature-sensitive cell cycle mutant by the use of mutant cells overexpressing the human epidermal growth factor receptor after transfection of the gene. J Cell Physiol. 1987 Dec; 133(3):461-70. Feige JJ, Scheffler IE. PMID: 3121640.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    60. Enhanced synthesis of the glucose/calcium-regulated proteins in a hamster cell mutant deficient in transfer of oligosaccharide core to polypeptides. J Cell Physiol. 1986 Dec; 129(3):277-82. Lee AS, Wells S, Kim KS, Scheffler IE. PMID: 3782307.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    61. Chinese hamster cells with a minichromosome containing the centromere region of human chromosome 1. Somat Cell Mol Genet. 1986 Sep; 12(5):479-91. Carine K, Solus J, Waltzer E, Manch-Citron J, Hamkalo BA, Scheffler IE. PMID: 3020713.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    62. Posttranscriptional regulation of ornithine decarboxylase activity. J Cell Physiol. 1986 Mar; 126(3):371-8. Dircks L, Grens A, Slezynger TC, Scheffler IE. PMID: 3081524.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    63. Chinese hamster cells deficient in ornithine decarboxylase activity: reversion by gene amplification and by azacytidine treatment. Somat Cell Mol Genet. 1985 Jan; 11(1):11-23. Steglich C, Grens A, Scheffler IE. PMID: 2579446.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    64. Localization of ornithine decarboxylase in mutant CHO cells that overproduce the enzyme. Differences between the intracellular distribution of monospecific ornithine decarboxylase antibodies and radiolabeled alpha-difluoromethylornithine. Eur J Cell Biol. 1984 Nov; 35(2):264-72. Anehus S, Emanuelsson H, Persson L, Sundler F, Scheffler IE, Heby O. PMID: 6440787.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    65. Chinese hamster ovary cells resistant to alpha-difluoromethylornithine are overproducers of ornithine decarboxylase. J Biol Chem. 1983 Oct 25; 258(20):12601-8. Choi JH, Scheffler IE. PMID: 6415054.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    66. Selection of ornithine decarboxylase-deficient mutants of Chinese hamster ovary cells. Methods Enzymol. 1983; 94:108-11. Steglich C, Scheffler IE. PMID: 6684725.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    67. Temperature-sensitive Chinese hamster fibroblast mutant with a defect in RNA metabolism. Mol Cell Biol. 1982 Dec; 2(12):1558-73. Wong EA, Scheffler IE. PMID: 14582197.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    68. Mapping of the genes of some components of the electron transport chain (complex I) on the X chromosome of mammals. Somatic Cell Genet. 1982 Nov; 8(6):691-707. Day CE, Scheffler IE. PMID: 6819642.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    69. An ornithine decarboxylase-deficient mutant of Chinese hamster ovary cells. J Biol Chem. 1982 Apr 25; 257(8):4603-9. Steglich C, Scheffler IE. PMID: 7068654.
      View in: PubMed   Mentions: 37     Fields:    Translation:AnimalsCells
    70. Integrity of mitochondria in a mammalian cell mutant defective in mitochondrial protein synthesis. J Cell Biol. 1981 Jul; 90(1):108-15. Burnett KG, Scheffler IE. PMID: 6265473.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    71. A mutant of Chinese hamster ovary cells resistant to alpha-methyl- and alpha-difluoromethylornithine. Somatic Cell Genet. 1981 Mar; 7(2):219-33. Choi J, Scheffler IE. PMID: 6794163.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    72. Cell cycle-dependent regulation of thymidine kinase activity introduced into mouse LMTK- cells by DNA and chromatin-mediated gene transfer. Proc Natl Acad Sci U S A. 1981 Feb; 78(2):1119-23. Schlosser CA, Steglich C, deWet JR, Scheffler IE. PMID: 6940130.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    73. Enzyme induction in a temperature-sensitive cell cycle mutant of Chinese hamster fibroblasts. J Cell Physiol. 1980 Nov; 105(2):209-20. Landy-Otsuka F, Scheffler IE. PMID: 7462327.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    74. Cytoplasmic inheritance of oligomycin resistance in Chinese hamster ovary cells. J Cell Biol. 1980 Sep; 86(3):723-9. Breen GA, Scheffler IE. PMID: 6447704.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    75. The energy charge in wild-type and respiration-deficient Chinese hamster cell mutants. J Cell Physiol. 1980 Apr; 103(1):169-72. Soderberg K, Nissinen E, Bakay B, Scheffler IE. PMID: 7191856.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    76. Assignment of a gene for succinate dehydrogenase to human chromosome 1 by somatic cell hybridization. Cytogenet Cell Genet. 1980; 28(1-2):121-35. Mascarello JT, Soderberg K, Scheffler IE. PMID: 6934864.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    77. Biochemical and genetic characterization of three hamster cell mutants resistant to diphtheria toxin. J Cell Biol. 1979 Oct; 83(1):116-25. Draper RK, Chin D, Eurey-Owens D, Scheffler IE, Simon MI. PMID: 117016.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    78. Respiration-deficient Chinese hamster cell mutants: biochemical characterization. Somatic Cell Genet. 1979 Jul; 5(4):441-51. Breen GA, Scheffler IE. PMID: 494059.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    79. Respiration-deficient Chinese hamster cell mutants: genetic characterization. Somatic Cell Genet. 1979 Mar; 5(2):225-40. Soderberg K, Mascarello JT, Breen GA, Scheffler IE. PMID: 483122.
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    80. Lipid-saccharide intermediates and glycoprotein biosynthesis in a temperature-sensitive Chinese hamster cell mutant. J Cell Physiol. 1979 Feb; 98(2):251-66. Tenner AJ, Scheffler IE. PMID: 217883.
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    81. Induction of ornithine decarboxylase activity in a temperature-sensitive cell cycle mutant of Chinese hamster cells. Proc Natl Acad Sci U S A. 1978 Oct; 75(10):5001-5. Landy-Otsuka F, Scheffler IE. PMID: 283409.
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    82. Chinese hamster cell mutant with defective mitochondrial protein synthesis. Nature. 1977 Jul 07; 268(5615):64-7. Ditta G, Soderberg K, Scheffler IE. PMID: 196202.
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    83. Mammalian cells with defective mitochondrial functions: a Chinese hamster mutant cell line lacking succinate dehydrogenase activity. Cell. 1977 Apr; 10(4):697-702. Soderberg KL, Ditta GS, Scheffler IE. PMID: 558831.
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    84. Glycoprotein synthesis in a temperature-sensitive Chinese hamster cell cycle mutant. J Cell Physiol. 1977 Feb; 90(2):145-60. Tenner A, Zieg J, Scheffler IE. PMID: 557044.
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    85. A respiration-deficient Chinese hamster cell line with a defect in NADH-coenzyme Q reductase. J Biol Chem. 1976 Aug 10; 251(15):4588-95. DeFrancesco L, Scheffler IE, Bissell MJ. PMID: 947896.
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    86. The selection of Chinese hamster cells deficient in oxidative energy metabolism. Somatic Cell Genet. 1976 Jul; 2(4):331-44. Ditta G, Soderberg K, Landy F, Scheffler IE. PMID: 1027147.
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    87. Conditionally lethal mutations in chinese hamster cells. Characterization of a cell line with a possible defect in the Krebs cycle. J Cell Physiol. 1975 Apr; 85(2 Pt 1):293-305. DeFrancesco L, Werntz D, Scheffler IE. PMID: 1123408.
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    88. Isopycnic centrifugation of chromatin in renografin solutions. J Cell Biol. 1974 Jun; 61(3):780-8. Chan RT, Scheffler IE. PMID: 4836392.
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    89. Conditional lethal mutants of Chinese hamster cells: mutants requiring exogenous carbondioxide for growth. J Cell Physiol. 1974 Apr; 83(2):219-30. Scheffler IE. PMID: 4822527.
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    90. Conditionally lethal mutations in Chinese hamster cells. I. Isolation of a temperature-sensitive line and its investigation by cell cycle studies. J Cell Physiol. 1973 Apr; 81(2):199-216. Scheffler IE, Buttin G. PMID: 4348554.
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    91. Genetic approach to DNA replication and its control in Escherichia coli. Fed Proc. 1972 Sep-Oct; 31(5):1422-7. Hirota Y, Mordoh J, Scheffler I, Jacob F. PMID: 4561641.
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