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Ramirez-Sanchez, Israel

TitleAssistant Project Scientist
InstitutionUniversity of California San Diego
DepartmentMedicine
Address9500 Gilman Drive #0613-J
La Jolla CA 92093
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Ramirez-Sanchez I, Mansour C, Navarrete-Yañez V, Ayala-Hernandez M, Guevara G, Castillo C, Loredo M, Bustamante M, Ceballos G, Villarreal FJ. (-)-Epicatechin induced reversal of endothelial cell aging and improved vascular function: underlying mechanisms. Food Funct. 2018 Aug 21. PMID: 30129961.
      View in: PubMed
    2. Sarmiento V, Ramirez-Sanchez I, Moreno-Ulloa A, Romero-Perez D, Chávez D, Ortiz M, Najera N, Correa-Basurto J, Villarreal F, Ceballos G. Synthesis of novel (-)-epicatechin derivatives as potential endothelial GPER agonists: Evaluation of biological effects. Bioorg Med Chem Lett. 2018 Feb 15; 28(4):658-663. PMID: 29395974.
      View in: PubMed
    3. Ortiz-Vilchis P, Ortiz-Flores M, Pacheco M, Ramirez-Sanchez I, Moreno-Ulloa A, Vega L, Ortiz A, Villarreal F, Rubio-Gayosso I, Najera N, Meaney E, Ceballos G. The cardioprotective effects of (-)-Epicatechin are mediated through arginase activity inhibition in a murine model of ischemia/reperfusion. Eur J Pharmacol. 2018 Jan 05; 818:335-342. PMID: 29126791.
      View in: PubMed
    4. Estrada-Mena FJ, Rodriguez A, Mendoza-Lorenzo P, Neri-Gomez T, Manjarrez-Gutierrez G, Perez-Ortiz AC, Ordonez-Razo R, Ceballos G, Villarreal F, Ramirez-Sanchez I. Effects of (-)-epicatechin on frontal cortex DAPC and dysbindin of the mdx mice. Neurosci Lett. 2017 Sep 29; 658:142-149. PMID: 28855126.
      View in: PubMed
    5. Guevara-Balcazar G, Ramirez-Sanchez I, Mera-Jimenez E, Rubio-Gayosso I, Aguilar-Najera ME, Castillo-Hernandez MC. Participation of COX-1 and COX-2 in the contractile effect of phenylephrine in prepubescent and old rats. Korean J Physiol Pharmacol. 2017 Jul; 21(4):407-413. PMID: 28706454.
      View in: PubMed
    6. Varela CE, Rodriguez A, Romero-Valdovinos M, Mendoza-Lorenzo P, Mansour C, Ceballos G, Villarreal F, Ramirez-Sanchez I. Browning effects of (-)-epicatechin on adipocytes and white adipose tissue. Eur J Pharmacol. 2017 Sep 15; 811:48-59. PMID: 28576408.
      View in: PubMed
    7. Taub PR, Ramirez-Sanchez I, Patel M, Higginbotham E, Moreno-Ulloa A, Román-Pintos LM, Phillips P, Perkins G, Ceballos G, Villarreal F. Beneficial effects of dark chocolate on exercise capacity in sedentary subjects: underlying mechanisms. A double blind, randomized, placebo controlled trial. Food Funct. 2016 Sep 14; 7(9):3686-93. PMID: 27491778; PMCID: PMC5025384 [Available on 09/14/17].
      View in: PubMed, PubMed Central
    8. Varela CE, Fromentin E, Roller M, Villarreal F, Ramirez-Sanchez I. Effects of a natural extract of Aronia Melanocarpa berry on endothelial cell nitric oxide production. J Food Biochem. 2016 Aug; 40(4):404-410. PMID: 27616799.
      View in: PubMed
    9. Guevara-Balcazar G, Villavicencio-Acevedo N, Kormanovski A, Villanueva C, Lara-Padilla E, Ramirez-Sanchez I, Castillo-Hernandez C.Oxidative stress and vascular reactivity changes in thoracic and abdominal aorta of rat exposed to hyperbaric oxygenation. Int J Pharmacol. 2015; 6(11):611-617.
    10. Moreno-Ulloa A, Mendez-Luna D, Beltran-Partida E, Castillo C, Guevara G, Ramirez-Sanchez I, Correa-Basurto J, Ceballos G, Villarreal F. The effects of (-)-epicatechin on endothelial cells involve the G protein-coupled estrogen receptor (GPER). Pharmacol Res. 2015 Oct; 100:309-20. PMID: 26303816; PMCID: PMC4555879 [Available on 10/01/16].
      View in: PubMed, PubMed Central
    11. Barnett CF, Moreno-Ulloa A, Shiva S, Ramirez-Sanchez I, Taub PR, Su Y, Ceballos G, Dugar S, Schreiner G, Villarreal F. Pharmacokinetic, partial pharmacodynamic and initial safety analysis of (-)-epicatechin in healthy volunteers. Food Funct. 2015 Mar; 6(3):824-33. PMID: 25598082; PMCID: PMC4357542.
      View in: PubMed, PubMed Central
    12. Ramirez-Sanchez I, De los Santos S, Gonzalez-Basurto S, Canto P, Mendoza-Lorenzo P, Palma-Flores C, Ceballos-Reyes G, Villarreal F, Zentella-Dehesa A, Coral-Vazquez R. (-)-Epicatechin improves mitochondrial-related protein levels and ameliorates oxidative stress in dystrophic d-sarcoglycan null mouse striated muscle. FEBS J. 2014 Dec; 281(24):5567-80. PMID: 25284161; PMCID: PMC4262719.
      View in: PubMed, PubMed Central
    13. Ortiz-Vilchis P, Yamazaki KG, Rubio-Gayosso I, Ramirez-Sanchez I, Calzada C, Romero-Perez D, Ortiz A, Meaney E, Taub P, Villarreal F, Ceballos G. Co-administration of the flavanol (-)-epicatechin with doxycycline synergistically reduces infarct size in a model of ischemia reperfusion injury by inhibition of mitochondrial swelling. Eur J Pharmacol. 2014 Dec 05; 744:76-82. PMID: 25281837.
      View in: PubMed
    14. Moreno-Ulloa A, Nogueira L, Rodriguez A, Barboza J, Hogan MC, Ceballos G, Villarreal F, Ramirez-Sanchez I. Recovery of Indicators of Mitochondrial Biogenesis, Oxidative Stress, and Aging With (-)-Epicatechin in Senile Mice. J Gerontol A Biol Sci Med Sci. 2015 Nov; 70(11):1370-8. PMID: 25143004; PMCID: PMC4715241 [Available on 11/01/16].
      View in: PubMed, PubMed Central
    15. Moreno-Ulloa A, Romero-Perez D, Villarreal F, Ceballos G, Ramirez-Sanchez I. Cell membrane mediated (-)-epicatechin effects on upstream endothelial cell signaling: evidence for a surface receptor. Bioorg Med Chem Lett. 2014 Jun 15; 24(12):2749-52. PMID: 24794111; PMCID: PMC4157920.
      View in: PubMed, PubMed Central
    16. Gutiérrez-Salmeán G, Ortiz-Vilchis P, Vacaseydel CM, Rubio-Gayosso I, Meaney E, Villarreal F, Ramírez-Sánchez I, Ceballos G. Acute effects of an oral supplement of (-)-epicatechin on postprandial fat and carbohydrate metabolism in normal and overweight subjects. Food Funct. 2014 Mar; 5(3):521-7. PMID: 24458104; PMCID: PMC3947792.
      View in: PubMed, PubMed Central
    17. Aguilar H, Fricovsky E, Ihm S, Schimke M, Maya-Ramos L, Aroonsakool N, Ceballos G, Dillmann W, Villarreal F, Ramirez-Sanchez I. Role for high-glucose-induced protein O-GlcNAcylation in stimulating cardiac fibroblast collagen synthesis. Am J Physiol Cell Physiol. 2014 May 01; 306(9):C794-804. PMID: 24553187; PMCID: PMC4010805.
      View in: PubMed, PubMed Central
    18. Gutiérrez-Salmeán G, Ortiz-Vilchis P, Vacaseydel CM, Garduño-Siciliano L, Chamorro-Cevallos G, Meaney E, Villafaña S, Villarreal F, Ceballos G, Ramírez-Sánchez I. Effects of (-)-epicatechin on a diet-induced rat model of cardiometabolic risk factors. Eur J Pharmacol. 2014 Apr 05; 728:24-30. PMID: 24491839.
      View in: PubMed
    19. Meaney A, Ceballos-Reyes G, Gutiérrez-Salmean G, Samaniego-Méndez V, Vela-Huerta A, Alcocer L, Zárate-Chavarría E, Mendoza-Castelán E, Olivares-Corichi I, García-Sánchez R, Martínez-Marroquín Y, Ramírez-Sánchez I, Meaney E. Cardiovascular risk factors in a Mexican middle-class urban population. The Lindavista Study. Baseline data. Arch Cardiol Mex. 2013 Oct-Dec; 83(4):249-56. PMID: 24215681.
      View in: PubMed
    20. Gutierrez-Salmean G, Ciaraldi TP, Nogueira L, Barboza J, Taub PR, Hogan MC, Henry RR, Meaney E, Villarreal F, Ceballos G, Ramirez-Sanchez I. Effects of (-)-epicatechin on molecular modulators of skeletal muscle growth and differentiation. J Nutr Biochem. 2014 Jan; 25(1):91-4. PMID: 24314870; PMCID: PMC3857584.
      View in: PubMed, PubMed Central
    21. Taub PR, Ramirez-Sanchez I, Ciaraldi TP, Gonzalez-Basurto S, Coral-Vazquez R, Perkins G, Hogan M, Maisel AS, Henry RR, Ceballos G, Villarreal F. Perturbations in skeletal muscle sarcomere structure in patients with heart failure and type 2 diabetes: restorative effects of (-)-epicatechin-rich cocoa. Clin Sci (Lond). 2013 Oct; 125(8):383-9. PMID: 23642227.
      View in: PubMed
    22. Palma-Flores C, Ramírez-Sánchez I, Rosas-Vargas H, Canto P, Coral-Vázquez RM. Description of a utrophin associated protein complex in lipid raft domains of human artery smooth muscle cells. Biochim Biophys Acta. 2014 Mar; 1838(3):1047-54. PMID: 24060563.
      View in: PubMed
    23. Ramirez-Sanchez I, Taub PR, Ciaraldi TP, Nogueira L, Coe T, Perkins G, Hogan M, Maisel AS, Henry RR, Ceballos G, Villarreal F. (-)-Epicatechin rich cocoa mediated modulation of oxidative stress regulators in skeletal muscle of heart failure and type 2 diabetes patients. Int J Cardiol. 2013 Oct 09; 168(4):3982-3990. PMID: 23870648; PMCID: PMC3805662.
      View in: PubMed, PubMed Central
    24. Moreno-Ulloa A, Cid A, Rubio-Gayosso I, Ceballos G, Villarreal F, Ramirez-Sanchez I. Effects of (-)-epicatechin and derivatives on nitric oxide mediated induction of mitochondrial proteins. Bioorg Med Chem Lett. 2013 Aug 01; 23(15):4441-6. PMID: 23791569; PMCID: PMC3741049.
      View in: PubMed, PubMed Central
    25. Gutiérrez-Salmeán G, Meaney A, Ocharán ME, Araujo JM, Ramírez-Sánchez I, Olivares-Corichi IM, García-Sánchez R, Castillo G, Méndez-Bolaina E, Meaney E, Ceballos G.Anthropometric traits, blood pressure, and dietary and physical exercise habits in health sciences students: The Obesity Observatory Project. Nutricion Hospitalaria. 2013; 1(28):194-201.
    26. Rubio-Gayosso I, Ramirez-Sanchez I, Ita-Islas I, Ortiz-Vilchis P, Gutierrez-Salmean G, Meaney A, Palma I, Olivares I, Garcia R, Meaney E, Ceballos G. Testosterone metabolites mediate its effects on myocardial damage induced by ischemia/reperfusion in male Wistar rats. Steroids. 2013 Mar; 78(3):362-9. PMID: 23276633.
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    27. Ramirez-Sanchez I, Nogueira L, Moreno A, Murphy A, Taub P, Perkins G, Ceballos GM, Hogan M, Malek M, Villarreal F. Stimulatory effects of the flavanol (-)-epicatechin on cardiac angiogenesis: additive effects with exercise. J Cardiovasc Pharmacol. 2012 Nov; 60(5):429-38. PMID: 22833114; PMCID: PMC3496054.
      View in: PubMed, PubMed Central
    28. Ramirez-Sanchez I, Aguilar H, Ceballos G, Villarreal F. (-)-Epicatechin-induced calcium independent eNOS activation: roles of HSP90 and AKT. Mol Cell Biochem. 2012 Nov; 370(1-2):141-50. PMID: 22865466; PMCID: PMC3812804.
      View in: PubMed, PubMed Central
    29. Meaney E, Sierra-Vargas P, Meaney A, Guzmán-Grenfell M, Ramírez-Sánchez I, Hicks JJ, Olivares-Corichi I, Ceballos G. Does metformin increase paraoxonase activity in patients with the metabolic syndrome? Additional data from the MEFISTO study. Clin Transl Sci. 2012 Jun; 5(3):265-8. PMID: 22686204.
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    30. Ramírez-Sánchez I, Mendoza-Lorenzo P, Zentella-Dehesa A, Méndez-Bolaina E, Lara-Padilla E, Ceballos-Reyes G, Canto P, Palma-Flores C, Coral-Vázquez RM. Caveolae and non-caveolae lipid raft microdomains of human umbilical vein endothelial cells contain utrophin-associated protein complexes. Biochimie. 2012 Sep; 94(9):1884-90. PMID: 22609462.
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    31. Taub PR, Ramirez-Sanchez I, Ciaraldi TP, Perkins G, Murphy AN, Naviaux R, Hogan M, Maisel AS, Henry RR, Ceballos G, Villarreal F. Alterations in skeletal muscle indicators of mitochondrial structure and biogenesis in patients with type 2 diabetes and heart failure: effects of epicatechin rich cocoa. Clin Transl Sci. 2012 Feb; 5(1):43-7. PMID: 22376256.
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    32. Nogueira L, Ramirez-Sanchez I, Perkins GA, Murphy A, Taub PR, Ceballos G, Villarreal FJ, Hogan MC, Malek MH. (-)-Epicatechin enhances fatigue resistance and oxidative capacity in mouse muscle. J Physiol. 2011 Sep 15; 589(Pt 18):4615-31. PMID: 21788351; PMCID: PMC3208228.
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    33. García-Pérez BE, Villagómez-Palatto DA, Castañeda-Sánchez JI, Coral-Vázquez RM, Ramírez-Sánchez I, Ordoñez-Razo RM, Luna-Herrera J. Innate response of human endothelial cells infected with mycobacteria. Immunobiology. 2011 Aug; 216(8):925-35. PMID: 21397978.
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    34. Ramirez-Sanchez I, Maya L, Ceballos G, Villarreal F. (-)-Epicatechin induces calcium and translocation independent eNOS activation in arterial endothelial cells. Am J Physiol Cell Physiol. 2011 Apr; 300(4):C880-7. PMID: 21209365; PMCID: PMC3074631.
      View in: PubMed, PubMed Central
    35. Ramirez-Sanchez I, Maya L, Ceballos G, Villarreal F. Fluorescent detection of (-)-epicatechin in microsamples from cacao seeds and cocoa products: Comparison with Folin-Ciocalteu method. J Food Compost Anal. 2010 Dec 01; 23(8):790-793. PMID: 21297935.
      View in: PubMed
    36. Ramirez-Sanchez I, Maya L, Ceballos G, Villarreal F. (-)-epicatechin activation of endothelial cell endothelial nitric oxide synthase, nitric oxide, and related signaling pathways. Hypertension. 2010 Jun; 55(6):1398-405. PMID: 20404222; PMCID: PMC2874202.
      View in: PubMed, PubMed Central
    37. Villarreal F, Epperson SA, Ramirez-Sanchez I, Yamazaki KG, Brunton LL. Regulation of cardiac fibroblast collagen synthesis by adenosine: roles for Epac and PI3K. Am J Physiol Cell Physiol. 2009 May; 296(5):C1178-84. PMID: 19279233; PMCID: PMC2681376.
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    38. Epperson SA, Brunton LL, Ramirez-Sanchez I, Villarreal F. Adenosine receptors and second messenger signaling pathways in rat cardiac fibroblasts. Am J Physiol Cell Physiol. 2009 May; 296(5):C1171-7. PMID: 19244482; PMCID: PMC2681375.
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    39. Rodriguez-Hernandez A, Rubio-Gayosso I, Ramirez-Sanchez I, Ita-Islas I, Meaney E, Gaxiola S, Meaney A, Asbun J, Figueroa-Valverde L, Ceballos G.Intraluminal restricted 17ß-estradiol exerts the same myocardial protection against ischemia/reperfusion injury in vivo as free 17ß-estradiol. Steroids. 2008; 5(73):528-538.
    40. Guevara-Balcazar G, Rubio-Gayosso I, Miliar-Garcia A, Castillo C, Ramirez-Sanchez I, Meaney E, Meaney A, Gomez E, Rubio R, Ceballos G. Mannose polymer induces vasodilation through a luminal mannose receptor in rat mesenteric arteries. Front Biosci. 2008 May 01; 13:5294-303. PMID: 18508587.
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    41. Méndez-Bolaina E, Sánchez-González J, Ramírez-Sánchez I, Ocharán-Hernández E, Núñez-Sánchez M, Meaney-Mendiolea E, Meaney A, Asbun-Bojalil J, Miliar-García A, Olivares-Corichi I, Ceballos-Reyes G. Effect of caveolin-1 scaffolding peptide and 17beta-estradiol on intracellular Ca2+ kinetics evoked by angiotensin II in human vascular smooth muscle cells. Am J Physiol Cell Physiol. 2007 Dec; 293(6):C1953-61. PMID: 17942630.
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    42. Ramirez-Sanchez I, Ceballos-Reyes G, Rosas-Vargas H, Cerecedo-Mercado D, Zentella-Dehesa A, Salamanca F, Coral-Vazquez RM. Expression and function of utrophin associated protein complex in stretched endothelial cells: dissociation and activation of eNOS. Front Biosci. 2007 Jan 01; 12:1956-62. PMID: 17127434.
      View in: PubMed
    43. Mendez E, Calzada C, Ocharan E, Sierra A, Castillo C, Ramirez-Sanchez I, Meaney E, Meaney A, Asbun J, Miliar A, Herrera J, Ceballos G.Differential expression of a1-adrenergic receptor subtypes in coronary microvascular endothelial cell in culture. European Journal of Pharmacology. 2006; 1-3(546):127-133.
    44. I. Ramírez-Sánchez, H. Rosas-Vargas, G. Ceballos-Reyes, F. Salamanca, R.M. Coral-Vázquez. .Expression analysis of the sg-sspn complex in smooth muscle and endothelial cells of human umbilical cord vessels. Journal of Vascular Research. 2005; 1(42):1-7.
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