Gernot Walter

Title(s)	Emeritus Professor, Pathology
School	Health Sciences
Phone	858-534-1894
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Research

Research Activities and Funding

Role of PP2A in Lung Cancer
NIH/NCI R01CA118015Jan 1, 2008 - Dec 31, 2011
Role: Principal Investigator

Molecular Pathology of Cancer Training Grant
NIH/NCI T32CA077109Jul 1, 1998 - Jul 31, 2010
Role: Co-Principal Investigator

PROTEIN PHOSPHATASE 2A AND TUMOR ANTIGENS IN CELL GROWTH
NIH/NCI R01CA036111Dec 1, 1983 - Nov 30, 2006
Role: Principal Investigator

Bibliographic

Publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.

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Walter G, Ruediger R. Mouse model for probing tumor suppressor activity of protein phosphatase 2A in diverse signaling pathways. Cell Cycle. 2012 Feb 01; 11(3):451-9. PMID: 22262169; PMCID: PMC3315090.

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Ruediger R, Ruiz J, Walter G. Human cancer-associated mutations in the Aa subunit of protein phosphatase 2A increase lung cancer incidence in Aa knock-in and knockout mice. Mol Cell Biol. 2011 Sep; 31(18):3832-44. PMID: 21791616; PMCID: PMC3165721.

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Ruediger R, Zhou J, Walter G. Mutagenesis and expression of the scaffolding Aalpha and Abeta subunits of PP2A: assays for measuring defects in binding of cancer-related Aalpha and Abeta mutants to the regulatory B and catalytic C subunits. Methods Mol Biol. 2007; 365:85-99. PMID: 17200556.

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Walter G, Zhou J, Ruediger R. Purification of PP2A holoenzymes by sequential immunoprecipitation with anti-peptide antibodies. Methods Mol Biol. 2007; 365:113-26. PMID: 17200558.

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Petersen P, Chou DM, You Z, Hunter T, Walter JC, Walter G. Protein phosphatase 2A antagonizes ATM and ATR in a Cdk2- and Cdc7-independent DNA damage checkpoint. Mol Cell Biol. 2006 Mar; 26(5):1997-2011. PMID: 16479016; PMCID: PMC1430240.

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Zhou J, Pham HT, Ruediger R, Walter G. Characterization of the Aalpha and Abeta subunit isoforms of protein phosphatase 2A: differences in expression, subunit interaction, and evolution. Biochem J. 2003 Jan 15; 369(Pt 2):387-98. PMID: 12370081; PMCID: PMC1223084.

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Zhou J, Pham HT, Walter G. The formation and activity of PP2A holoenzymes do not depend on the isoform of the catalytic subunit. J Biol Chem. 2003 Mar 07; 278(10):8617-22. PMID: 12506124.

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Chou DM, Petersen P, Walter JC, Walter G. Protein phosphatase 2A regulates binding of Cdc45 to the prereplication complex. J Biol Chem. 2002 Oct 25; 277(43):40520-7. PMID: 12185086.

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Strack S, Ruediger R, Walter G, Dagda RK, Barwacz CA, Cribbs JT. Protein phosphatase 2A holoenzyme assembly: identification of contacts between B-family regulatory and scaffolding A subunits. J Biol Chem. 2002 Jun 07; 277(23):20750-5. PMID: 11929880.

View in: PubMed