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Bruce Ito

Title(s)Staff Res Assoc , Medicine
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Discovery of BMS-986235/LAR-1219: A Potent Formyl Peptide Receptor 2 (FPR2) Selective Agonist for the Prevention of Heart Failure. J Med Chem. 2020 09 10; 63(17):9003-9019. Asahina Y, Wurtz NR, Arakawa K, Carson N, Fujii K, Fukuchi K, Garcia R, Hsu MY, Ishiyama J, Ito B, Kick E, Lupisella J, Matsushima S, Ohata K, Ostrowski J, Saito Y, Tsuda K, Villarreal F, Yamada H, Yamaoka T, Wexler R, Gordon D, Kohno Y. PMID: 32407089.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    2. The role of inflammation in driving left ventricular remodeling in a pre-HFpEF model. Exp Biol Med (Maywood). 2020 04; 245(8):748-757. Loredo-Mendoza ML, Ramirez-Sanchez I, Bustamante-Pozo MM, Ayala M, Navarrete V, Garate-Carrillo A, Ito BR, Ceballos G, Omens J, Villarreal F. PMID: 32183553.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    3. Preservation of Post-Infarction Cardiac Structure and Function via Long-Term Oral Formyl Peptide Receptor Agonist Treatment. JACC Basic Transl Sci. 2019 Dec; 4(8):905-920. García RA, Ito BR, Lupisella JA, Carson NA, Hsu MY, Fernando G, Heroux M, Bouvier M, Dierks E, Kick EK, Gordon DA, Chen J, Mintier G, Carrier M, St-Onge S, Shah H, Towne J, Bucardo MS, Ma X, Ryan CS, Wurtz NR, Ostrowski J, Villarreal FJ. PMID: 31909300.
      View in: PubMed   Mentions:
    4. Low Intensity Epicardial Pacing During the Absolute Refractory Period Augments Left Ventricular Function Mediated by Local Catecholamine Release. J Cardiovasc Electrophysiol. 2016 09; 27(9):1102-9. Ito BR, Covell JW, Curtis GP. PMID: 27279561.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    5. Discordant signaling and autophagy response to fasting in hearts of obese mice: Implications for ischemia tolerance. Am J Physiol Heart Circ Physiol. 2016 07 01; 311(1):H219-28. Andres AM, Kooren JA, Parker SJ, Tucker KC, Ravindran N, Ito BR, Huang C, Venkatraman V, Van Eyk JE, Gottlieb RA, Mentzer RM. PMID: 27199111.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    6. Autophagy and the human heart. J Thorac Cardiovasc Surg. 2014 Jul; 148(1):369-70. Ito BR, Gottlieb RA, Mentzer RM. PMID: 24939031.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    7. Activation of the homeostatic intracellular repair response during cardiac surgery. J Am Coll Surg. 2013 Apr; 216(4):719-26; discussion 726-9. Jahania SM, Sengstock D, Vaitkevicius P, Andres A, Ito BR, Gottlieb RA, Mentzer RM. PMID: 23415552.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    8. Reduction of hepatic steatosis in rats and mice after treatment with a liver-targeted thyroid hormone receptor agonist. Hepatology. 2009 Feb; 49(2):407-17. Cable EE, Finn PD, Stebbins JW, Hou J, Ito BR, van Poelje PD, Linemeyer DL, Erion MD. PMID: 19072834.
      View in: PubMed   Mentions: 50     Fields:    Translation:AnimalsCells
    9. Preclinical pharmacokinetics of a HepDirect prodrug of a novel phosphonate-containing thyroid hormone receptor agonist. Drug Metab Dispos. 2008 Nov; 36(11):2393-403. Fujitaki JM, Cable EE, Ito BR, Zhang BH, Hou J, Yang C, Bullough DA, Ferrero JL, van Poelje PD, Linemeyer DL, Erion MD. PMID: 18703645.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    10. Targeting thyroid hormone receptor-beta agonists to the liver reduces cholesterol and triglycerides and improves the therapeutic index. Proc Natl Acad Sci U S A. 2007 Sep 25; 104(39):15490-5. Erion MD, Cable EE, Ito BR, Jiang H, Fujitaki JM, Finn PD, Zhang BH, Hou J, Boyer SH, van Poelje PD, Linemeyer DL. PMID: 17878314.
      View in: PubMed   Mentions: 63     Fields:    Translation:Animals
    11. Functional effects of enhancing or silencing adenosine A2b receptors in cardiac fibroblasts. . 2004 Dec; 287(6):H2478-86. Chen Y, Epperson S, Makhsudova L, Ito B, Suarez J, Dillmann W, Villarreal F. PMID: 15284071.
      View in: PubMed   Mentions:
    12. Modulation of cardiac remodeling by adenosine: in vitro and in vivo effects. Mol Cell Biochem. 2003 Sep; 251(1-2):17-26. Villarreal F, Zimmermann S, Makhsudova L, Montag AC, Erion MD, Bullough DA, Ito BR. PMID: 14575299.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimals
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