Shunhui Zhuang

Title(s)SRA 2, Medicine
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. A plasma membrane-associated form of the androgen receptor enhances nuclear androgen signaling in osteoblasts and prostate cancer cells. Sci Signal. 2024 Jan 30; 17(821):eadi7861. Kalyanaraman H, Casteel DE, China SP, Zhuang S, Boss GR, Pilz RB. PMID: 38289986; PMCID: PMC10916501.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    2. The Antioxidant/Nitric Oxide-Quenching Agent Cobinamide Prevents Aortic Disease in a Mouse Model of Marfan Syndrome. JACC Basic Transl Sci. 2024 Jan; 9(1):46-62. Kalyanaraman H, Casteel DE, Cabriales JA, Tat J, Zhuang S, Chan A, Dretchen KL, Boss GR, Pilz RB. PMID: 38362350; PMCID: PMC10864892.
      View in: PubMed   Mentions:
    3. Cobinamide is a strong and versatile antioxidant that overcomes oxidative stress in cells, flies, and diabetic mice. PNAS Nexus. 2022 Sep; 1(4):pgac191. Chang S, Tat J, China SP, Kalyanaraman H, Zhuang S, Chan A, Lai C, Radic Z, Abdel-Rahman EA, Casteel DE, Pilz RB, Ali SS, Boss GR. PMID: 36276587; PMCID: PMC9578022.
      View in: PubMed   Mentions: 2  
    4. Constitutive protein kinase G activation exacerbates stress-induced cardiomyopathy. Br J Pharmacol. 2022 06; 179(11):2413-2429. Schwaerzer GK, Casteel DE, Cividini F, Kalyanaraman H, Zhuang S, Gu Y, Dalton ND, Peterson KL, Dillmann WH, Boss GR, Pilz RB. PMID: 34000062; PMCID: PMC9926932.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    5. Metabolic interaction between amino acid deprivation and cisplatin synergistically reduces phosphoribosyl-pyrophosphate and augments cisplatin cytotoxicity. Sci Rep. 2020 11 16; 10(1):19907. Wahwah N, Dhar D, Chen H, Zhuang S, Chan A, Casteel DE, Kalyanaraman H, Pilz RB, Boss GR. PMID: 33199755; PMCID: PMC7670436.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    6. Aortic pathology from protein kinase G activation is prevented by an antioxidant vitamin B12 analog. Nat Commun. 2019 08 06; 10(1):3533. Schwaerzer GK, Kalyanaraman H, Casteel DE, Dalton ND, Gu Y, Lee S, Zhuang S, Wahwah N, Schilling JM, Patel HH, Zhang Q, Makino A, Milewicz DM, Peterson KL, Boss GR, Pilz RB. PMID: 31387997; PMCID: PMC6684604.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    7. The activity of cGMP-dependent protein kinase Iα is not directly regulated by oxidation-induced disulfide formation at cysteine 43. J Biol Chem. 2017 05 19; 292(20):8262-8268. Kalyanaraman H, Zhuang S, Pilz RB, Casteel DE. PMID: 28360102; PMCID: PMC5437233.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    8. Akt phosphorylation and regulation of transketolase is a nodal point for amino acid control of purine synthesis. Mol Cell. 2014 Jul 17; 55(2):264-76. Saha A, Connelly S, Jiang J, Zhuang S, Amador DT, Phan T, Pilz RB, Boss GR. PMID: 24981175; PMCID: PMC4104231.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansAnimalsCells
    9. Nongenomic thyroid hormone signaling occurs through a plasma membrane-localized receptor. Sci Signal. 2014 May 20; 7(326):ra48. Kalyanaraman H, Schwappacher R, Joshua J, Zhuang S, Scott BT, Klos M, Casteel DE, Frangos JA, Dillmann W, Boss GR, Pilz RB. PMID: 24847117; PMCID: PMC6504257.
      View in: PubMed   Mentions: 51     Fields:    Translation:HumansAnimalsCells
    10. A molecular mechanism for therapeutic effects of cGMP-elevating agents in pulmonary arterial hypertension. J Biol Chem. 2013 Jun 07; 288(23):16557-16566. Schwappacher R, Kilic A, Kojonazarov B, Lang M, Diep T, Zhuang S, Gawlowski T, Schermuly RT, Pfeifer A, Boss GR, Pilz RB. PMID: 23612967; PMCID: PMC3675591.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    11. Rho isoform-specific interaction with IQGAP1 promotes breast cancer cell proliferation and migration. J Biol Chem. 2012 Nov 02; 287(45):38367-78. Casteel DE, Turner S, Schwappacher R, Rangaswami H, Su-Yuo J, Zhuang S, Boss GR, Pilz RB. PMID: 22992742; PMCID: PMC3488105.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansCells
    12. Protein kinase G and focal adhesion kinase converge on Src/Akt/β-catenin signaling module in osteoblast mechanotransduction. J Biol Chem. 2012 Jun 15; 287(25):21509-19. Rangaswami H, Schwappacher R, Tran T, Chan GC, Zhuang S, Boss GR, Pilz RB. PMID: 22563076; PMCID: PMC3375572.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
    13. Pro-survival effects of 17β-estradiol on osteocytes are mediated by nitric oxide/cGMP via differential actions of cGMP-dependent protein kinases I and II. J Biol Chem. 2012 Jan 06; 287(2):978-88. Marathe N, Rangaswami H, Zhuang S, Boss GR, Pilz RB. PMID: 22117068; PMCID: PMC3256896.
      View in: PubMed   Mentions: 50     Fields:    Translation:AnimalsCells
    14. Cyclic GMP and protein kinase G control a Src-containing mechanosome in osteoblasts. Sci Signal. 2010 Dec 21; 3(153):ra91. Rangaswami H, Schwappacher R, Marathe N, Zhuang S, Casteel DE, Haas B, Chen Y, Pfeifer A, Kato H, Shattil S, Boss GR, Pilz RB. PMID: 21177494; PMCID: PMC3093297.
      View in: PubMed   Mentions: 51     Fields:    Translation:AnimalsCells
    15. Type II cGMP-dependent protein kinase mediates osteoblast mechanotransduction. J Biol Chem. 2009 May 29; 284(22):14796-808. Rangaswami H, Marathe N, Zhuang S, Chen Y, Yeh JC, Frangos JA, Boss GR, Pilz RB. PMID: 19282289; PMCID: PMC2685661.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansAnimalsCells
    16. A DNA polymerase-{alpha}{middle dot}primase cofactor with homology to replication protein A-32 regulates DNA replication in mammalian cells. J Biol Chem. 2009 Feb 27; 284(9):5807-18. Casteel DE, Zhuang S, Zeng Y, Perrino FW, Boss GR, Goulian M, Pilz RB. PMID: 19119139; PMCID: PMC2645831.
      View in: PubMed   Mentions: 112     Fields:    Translation:HumansAnimalsCells
    17. cGMP-dependent protein kinase anchoring by IRAG regulates its nuclear translocation and transcriptional activity. Cell Signal. 2008 Jul; 20(7):1392-9. Casteel DE, Zhang T, Zhuang S, Pilz RB. PMID: 18450420; PMCID: PMC2477739.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    18. A cysteine-rich LIM-only protein mediates regulation of smooth muscle-specific gene expression by cGMP-dependent protein kinase. J Biol Chem. 2007 Nov 16; 282(46):33367-33380. Zhang T, Zhuang S, Casteel DE, Looney DJ, Boss GR, Pilz RB. PMID: 17878170.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    19. Effects of lovastatin on Rho isoform expression, activity, and association with guanine nucleotide dissociation inhibitors. Biochem Pharmacol. 2008 Jan 15; 75(2):405-13. Turner SJ, Zhuang S, Zhang T, Boss GR, Pilz RB. PMID: 17920041; PMCID: PMC2228324.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    20. Cyanide detoxification by the cobalamin precursor cobinamide. Exp Biol Med (Maywood). 2006 May; 231(5):641-9. Broderick KE, Potluri P, Zhuang S, Scheffler IE, Sharma VS, Pilz RB, Boss GR. PMID: 16636313.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimalsCells
    21. Regulation of cGMP-dependent protein kinase expression by Rho and Kruppel-like transcription factor-4. J Biol Chem. 2006 Jun 23; 281(25):16951-16961. Zeng Y, Zhuang S, Gloddek J, Tseng CC, Boss GR, Pilz RB. PMID: 16632465.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    22. Cyclic GMP-dependent protein kinase regulates CCAAT enhancer-binding protein beta functions through inhibition of glycogen synthase kinase-3. J Biol Chem. 2005 Sep 23; 280(38):32683-92. Zhao X, Zhuang S, Chen Y, Boss GR, Pilz RB. PMID: 16055922.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    23. Nitric oxide scavenging by the cobalamin precursor cobinamide. J Biol Chem. 2005 Mar 11; 280(10):8678-85. Broderick KE, Singh V, Zhuang S, Kambo A, Chen JC, Sharma VS, Pilz RB, Boss GR. PMID: 15632180.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    24. Vasodilator-stimulated phosphoprotein activation of serum-response element-dependent transcription occurs downstream of RhoA and is inhibited by cGMP-dependent protein kinase phosphorylation. J Biol Chem. 2004 Mar 12; 279(11):10397-407. Zhuang S, Nguyen GT, Chen Y, Gudi T, Eigenthaler M, Jarchau T, Walter U, Boss GR, Pilz RB. PMID: 14679200.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    25. Synergism between calcium and cyclic GMP in cyclic AMP response element-dependent transcriptional regulation requires cooperation between CREB and C/EBP-beta. Mol Cell Biol. 2003 Jun; 23(12):4066-82. Chen Y, Zhuang S, Cassenaer S, Casteel DE, Gudi T, Boss GR, Pilz RB. PMID: 12773552; PMCID: PMC156132.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    26. Rheb is in a high activation state and inhibits B-Raf kinase in mammalian cells. Oncogene. 2002 Sep 12; 21(41):6356-65. Im E, von Lintig FC, Chen J, Zhuang S, Qui W, Chowdhury S, Worley PF, Boss GR, Pilz RB. PMID: 12214276.
      View in: PubMed   Mentions: 53     Fields:    Translation:AnimalsCells
    27. cGMP-dependent protein kinase I beta physically and functionally interacts with the transcriptional regulator TFII-I. J Biol Chem. 2002 Aug 30; 277(35):32003-14. Casteel DE, Zhuang S, Gudi T, Tang J, Vuica M, Desiderio S, Pilz RB. PMID: 12082086.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
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