Piyush Patel

Title(s)	Professor, Anesthesiology
School	Vc-health Sciences-schools
Address	9500 Gilman Drive # La Jolla CA 92093
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Research

Research Activities and Funding

Transcranial Laser Therapy of Ischemic Stroke
NIH U01NS069563Feb 1, 2011 - Aug 31, 2015
Role: Principal Investigator

The Role of RhoGTPases in Anesthetic-Mediated Neurotoxicity
NIH R01GM085179May 1, 2010 - Nov 30, 2020
Role: Principal Investigator

Microarray analysis of neuronal ischemic preconditioning
NIH R01NS047570Jun 1, 2004 - Mar 31, 2008
Role: Principal Investigator

Cerebal Ischemia During Anesthesia and Surgery
NIH R01GM052098Aug 1, 1995 - Apr 30, 2006
Role: Principal Investigator

CEREBRAL ISCHEMIA DURING ANESTHESIA AND SURGERY
NIH R29GM052098Aug 1, 1995 - Apr 30, 2001
Role: Principal Investigator

Bibliographic

Publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.

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Subpial delivery of adeno-associated virus 9-synapsin-caveolin-1 (AAV9-SynCav1) preserves motor neuron and neuromuscular junction morphology, motor function, delays disease onset, and extends survival in hSOD1G93A mice. Theranostics. 2022; 12(12):5389-5403. Wang S, Ichinomiya T, Savchenko P, Wang D, Sawada A, Li X, Duong T, Li W, Bonds JA, Kim EJ, Miyanohara A, Roth DM, Patel HH, Patel PM, Tadokoro T, Marsala M, Head BP. PMID: 35910808; PMCID: PMC9330519.

View in: PubMed Mentions: 2 Fields:
Dia Diagnostic Imaging Mol Molecular Biology Nan Nanotechnology The Therapeutics
Translation:Humans Animals Cells
Dietary Fiber and the Hippocampal Neurogenic Niche in a Model of Pelvic Radiotherapy. Neuroscience. 2021 11 01; 475:137-147. Devarakonda S, Malipatlolla DK, Patel P, Grandér R, Kuhn HG, Steineck G, Sjöberg F, Rascón A, Nyman M, Eriksson Y, Danial J, Ittner E, Naama Walid R, Prykhodko O, Masuram S, Kalm M, Bull C. PMID: 34487821.

View in: PubMed Mentions: Fields:
Neu Neurology
Translation:Animals Cells
Synapsin-caveolin-1 gene therapy preserves neuronal and synaptic morphology and prevents neurodegeneration in a mouse model of AD. Mol Ther Methods Clin Dev. 2021 Jun 11; 21:434-450. Wang S, Leem JS, Podvin S, Hook V, Kleschevnikov N, Savchenko P, Dhanani M, Zhou K, Kelly IC, Zhang T, Miyanohara A, Nguyen P, Kleschevnikov A, Wagner SL, Trojanowski JQ, Roth DM, Patel HH, Patel PM, Head BP. PMID: 33981778; PMCID: PMC8065227.

View in: PubMed Mentions: 9
Morphine induces physiological, structural, and molecular benefits in the diabetic myocardium. FASEB J. 2021 03; 35(3):e21407. Zemljic-Harpf AE, See Hoe LE, Schilling JM, Zuniga-Hertz JP, Nguyen A, Vaishnav YJ, Belza GJ, Budiono BP, Patel PM, Head BP, Dillmann WH, Mahata SK, Peart JN, Roth DM, Headrick JP, Patel HH. PMID: 33583084.

View in: PubMed Mentions: 1 Fields:
Bio Biology Phy Physiology
Translation:Humans Animals Cells
Dietary Oat Bran Reduces Systemic Inflammation in Mice Subjected to Pelvic Irradiation. Nutrients. 2020 Jul 22; 12(8). Patel P, Malipatlolla DK, Devarakonda S, Bull C, Rascón A, Nyman M, Stringer A, Tremaroli V, Steineck G, Sjöberg F. PMID: 32707913; PMCID: PMC7468988.

View in: PubMed Mentions: 5 Fields:
Nut Nutritional Sciences
Translation:Animals
Caveolin-1 Phosphorylation Is Essential for Axonal Growth of Human Neurons Derived From iPSCs. Front Cell Neurosci. 2019; 13:324. Wang S, Zhang Z, Almenar-Queralt A, Leem J, DerMardirossian C, Roth DM, Patel PM, Patel HH, Head BP. PMID: 31379509; PMCID: PMC6650578.

View in: PubMed Mentions: 4
Neuron-targeted caveolin-1 improves neuromuscular function and extends survival in SOD1G93A mice. FASEB J. 2019 06; 33(6):7545-7554. Sawada A, Wang S, Jian M, Leem J, Wackerbarth J, Egawa J, Schilling JM, Platoshyn O, Zemljic-Harpf A, Roth DM, Patel HH, Patel PM, Marsala M, Head BP. PMID: 30894019; PMCID: PMC6529340.

View in: PubMed Mentions: 13 Fields:
Bio Biology Phy Physiology
Translation:Humans Animals Cells
Relations of combat stress and posttraumatic stress disorder to 24-h plasma and cerebrospinal fluid interleukin-6 levels and circadian rhythmicity. Psychoneuroendocrinology. 2019 02; 100:237-245. Agorastos A, Hauger RL, Barkauskas DA, Lerman IR, Moeller-Bertram T, Snijders C, Haji U, Patel PM, Geracioti TD, Chrousos GP, Baker DG. PMID: 30390522.

View in: PubMed Mentions: 11 Fields:
End Endocrinology Neu Neurology Psy Psychiatry
Translation:Humans
Neuron-Targeted Caveolin-1 Promotes Ultrastructural and Functional Hippocampal Synaptic Plasticity. Cereb Cortex. 2018 09 01; 28(9):3255-3266. Egawa J, Zemljic-Harpf A, Mandyam CD, Niesman IR, Lysenko LV, Kleschevnikov AM, Roth DM, Patel HH, Patel PM, Head BP. PMID: 28981594; PMCID: PMC6095215.

View in: PubMed Mentions: 18 Fields:
Bra Brain
Translation:Animals Cells
Comparison of Efficacy and Safety of Fixed Dose Combination of Rosuvastatin and Choline Fenofibrate to Fixed Dose Combination of Rosuvastatin and Fenofibrate in Patients of Mixed Dyslipidemia: A Randomized, Open-label, Multicentre Clinical Trial in Indian Population. Indian J Endocrinol Metab. 2018 Sep-Oct; 22(5):627-631. Barkate H, Patel P, Shah D, Vyas F. PMID: 30294571; PMCID: PMC6166558.

View in: PubMed Mentions:
Neuron-specific caveolin-1 overexpression improves motor function and preserves memory in mice subjected to brain trauma. FASEB J. 2017 08; 31(8):3403-3411. Egawa J, Schilling JM, Cui W, Posadas E, Sawada A, Alas B, Zemljic-Harpf AE, Fannon-Pavlich MJ, Mandyam CD, Roth DM, Patel HH, Patel PM, Head BP. PMID: 28450301; PMCID: PMC5503707.

View in: PubMed Mentions: 10 Fields:
Bio Biology Phy Physiology
Translation:Animals Cells
Caveolin-1 regulation of disrupted-in-schizophrenia-1 as a potential therapeutic target for schizophrenia. J Neurophysiol. 2017 01 01; 117(1):436-444. Kassan A, Egawa J, Zhang Z, Almenar-Queralt A, Nguyen QM, Lajevardi Y, Kim K, Posadas E, Jeste DV, Roth DM, Patel PM, Patel HH, Head BP. PMID: 27832597; PMCID: PMC5253400.

View in: PubMed Mentions: 16 Fields:
Neu Neurology Phy Physiology
Translation:Humans Animals Cells
Caveolin-3 plays a critical role in autophagy after ischemia-reperfusion. Am J Physiol Cell Physiol. 2016 Dec 01; 311(6):C854-C865. Kassan A, Pham U, Nguyen Q, Reichelt ME, Cho E, Patel PM, Roth DM, Head BP, Patel HH. PMID: 27707689; PMCID: PMC5206298.

View in: PubMed Mentions: 12 Fields:
Cel Cell Biology Phy Physiology
Translation:Animals Cells
The Effect of Clevidipine on Cerebral Blood Flow Velocity and Carbon Dioxide Reactivity in Human Volunteers. J Neurosurg Anesthesiol. 2016 Oct; 28(4):337-40. Lemkuil BP, Gierl BT, Patel PM, Pearn ML, Nguyen LC, Minokadeh A, Drummond JC. PMID: 26447497.

View in: PubMed Mentions: 3 Fields:
Ane Anesthesiology Neu Neurosurgery
Translation:Humans
Posttraumatic stress disorder influences the nociceptive and intrathecal cytokine response to a painful stimulus in combat veterans. Psychoneuroendocrinology. 2016 11; 73:99-108. Lerman I, Davis BA, Bertram TM, Proudfoot J, Hauger RL, Coe CL, Patel PM, Baker DG. PMID: 27490714.

View in: PubMed Mentions: 17 Fields:
End Endocrinology Neu Neurology Psy Psychiatry
Translation:Humans
Comparison of efficacy and safety of choline fenofibrate (fenofibric acid) to micronized fenofibrate in patients of mixed dyslipidemia: A randomized, open-label, multicenter clinical trial in Indian population. Indian J Endocrinol Metab. 2016 Jan-Feb; 20(1):67-71. Patel P, Barkate H. PMID: 26904471; PMCID: PMC4743387.

View in: PubMed Mentions: 3
Membrane lipid rafts and neurobiology: age-related changes in membrane lipids and loss of neuronal function. J Physiol. 2016 08 15; 594(16):4565-79. Egawa J, Pearn ML, Lemkuil BP, Patel PM, Head BP. PMID: 26332795; PMCID: PMC4983616.

View in: PubMed Mentions: 68 Fields:
Phy Physiology
Translation:Humans Animals Cells
Neuron-Targeted Caveolin-1 Improves Molecular Signaling, Plasticity, and Behavior Dependent on the Hippocampus in Adult and Aged Mice. Biol Psychiatry. 2017 01 15; 81(2):101-110. Mandyam CD, Schilling JM, Cui W, Egawa J, Niesman IR, Kellerhals SE, Staples MC, Busija AR, Risbrough VB, Posadas E, Grogman GC, Chang JW, Roth DM, Patel PM, Patel HH, Head BP. PMID: 26592463; PMCID: PMC4826329.

View in: PubMed Mentions: 33 Fields:
Psy Psychiatry Psy Psychophysiology
Translation:Animals Cells
Metformin use and the risk of esophageal cancer in Barrett esophagus. South Med J. 2014 Dec; 107(12):774-9. Agrawal S, Patel P, Agrawal A, Makhijani N, Markert R, Deidrich W. PMID: 25502158.

View in: PubMed Mentions: 10 Fields:
Med Medicine (General)
Translation:Humans
Pushing the standards forward: in-depth monitoring of physiological parameters in anesthetized neonatal mice. Anesth Analg. 2014 Nov; 119(5):1029-31. Vutskits L, Patel P. PMID: 25329021.

View in: PubMed Mentions: 1 Fields:
Ane Anesthesiology
Translation:Animals
Review: effects of anesthetics on brain circuit formation. J Neurosurg Anesthesiol. 2014 Oct; 26(4):358-62. Wagner M, Ryu YK, Smith SC, Patel P, Mintz CD. PMID: 25144504; PMCID: PMC4700880.

View in: PubMed Mentions: 16 Fields:
Ane Anesthesiology Neu Neurosurgery
Translation:Humans
Cardioprotective trafficking of caveolin to mitochondria is Gi-protein dependent. Anesthesiology. 2014 Sep; 121(3):538-48. Wang J, Schilling JM, Niesman IR, Headrick JP, Finley JC, Kwan E, Patel PM, Head BP, Roth DM, Yue Y, Patel HH. PMID: 24821070; PMCID: PMC4219636.

View in: PubMed Mentions: 15 Fields:
Ane Anesthesiology
Translation:Animals Cells
Perioperative hypertension: white coat, masked, and appropriately referred for treatment. J Neurosurg Anesthesiol. 2014 Jul; 26(3):265. Drummond JC, Blake J, Patel PM, Clopton P, Schulteis G. PMID: 24275936.

View in: PubMed Mentions: 1 Fields:
Ane Anesthesiology Neu Neurosurgery
Translation:Humans
Evidence for acute central sensitization to prolonged experimental pain in posttraumatic stress disorder. Pain Med. 2014 May; 15(5):762-71. Moeller-Bertram T, Strigo IA, Simmons AN, Schilling JM, Patel P, Baker DG. PMID: 24738563.

View in: PubMed Mentions: 11 Fields:
Neu Neurology Pal Palliative Care Psy Psychophysiology
Translation:Humans
Long-term atorvastatin treatment leads to alterations in behavior, cognition, and hippocampal biochemistry. Behav Brain Res. 2014 Jul 01; 267:6-11. Schilling JM, Cui W, Godoy JC, Risbrough VB, Niesman IR, Roth DM, Patel PM, Drummond JC, Patel HH, Zemljic-Harpf AE, Head BP. PMID: 24657594; PMCID: PMC4059187.

View in: PubMed Mentions: 11 Fields:
Beh Behavioral Sciences Bra Brain
Translation:Animals
Circadian rhythmicity, variability and correlation of interleukin-6 levels in plasma and cerebrospinal fluid of healthy men. Psychoneuroendocrinology. 2014 Jun; 44:71-82. Agorastos A, Hauger RL, Barkauskas DA, Moeller-Bertram T, Clopton PL, Haji U, Lohr JB, Geracioti TD, Patel PM, Chrousos GP, Baker DG. PMID: 24767621.

View in: PubMed Mentions: 27 Fields:
End Endocrinology Neu Neurology Psy Psychiatry
Translation:Humans
Traumatic brain injury enhances neuroinflammation and lesion volume in caveolin deficient mice. J Neuroinflammation. 2014 Mar 03; 11:39. Niesman IR, Schilling JM, Shapiro LA, Kellerhals SE, Bonds JA, Kleschevnikov AM, Cui W, Voong A, Krajewski S, Ali SS, Roth DM, Patel HH, Patel PM, Head BP. PMID: 24593993; PMCID: PMC3975903.

View in: PubMed Mentions: 51 Fields:
Neu Neurology
Translation:Animals Cells
Randomized comparative trial of efficacy of paracetamol, ibuprofen and paracetamol-ibuprofen combination for treatment of febrile children. Perspect Clin Res. 2014 Jan; 5(1):25-31. Vyas FI, Rana DA, Patel PM, Patel VJ, Bhavsar RH. PMID: 24551584; PMCID: PMC3915365.

View in: PubMed Mentions: 5
Caveolin isoform switching as a molecular, structural, and metabolic regulator of microglia. Mol Cell Neurosci. 2013 Sep; 56:283-97. Niesman IR, Zemke N, Fridolfsson HN, Haushalter KJ, Levy K, Grove A, Schnoor R, Finley JC, Patel PM, Roth DM, Head BP, Patel HH. PMID: 23851187; PMCID: PMC3791173.

View in: PubMed Mentions: 17 Fields:
Cel Cell Biology Mol Molecular Biology Neu Neurology
Translation:Animals Cells
Characterization of cerebrospinal fluid (CSF) and plasma NPY levels in normal volunteers over a 24-h timeframe. Psychoneuroendocrinology. 2013 Oct; 38(10):2378-82. Baker DG, Bertram TM, Patel PM, Barkauskas DA, Clopton P, Patel S, Geracioti TD, Haji U, O'Connor DT, Nievergelt CM, Hauger RL. PMID: 23759334.

View in: PubMed Mentions: 13 Fields:
End Endocrinology Neu Neurology Psy Psychiatry
Translation:Humans
Epicatechin regulation of mitochondrial structure and function is opioid receptor dependent. Mol Nutr Food Res. 2013 Jun; 57(6):1007-14. Panneerselvam M, Ali SS, Finley JC, Kellerhals SE, Migita MY, Head BP, Patel PM, Roth DM, Patel HH. PMID: 23625721; PMCID: PMC3835714.

View in: PubMed Mentions: 14 Fields:
Nut Nutritional Sciences
Translation:Animals Cells
An observational study of the influence of "white-coat hypertension" on day-of-surgery blood pressure determinations. J Neurosurg Anesthesiol. 2013 Apr; 25(2):154-61. Drummond JC, Blake JL, Patel PM, Clopton P, Schulteis G. PMID: 23211641.

View in: PubMed Mentions: 12 Fields:
Ane Anesthesiology Neu Neurosurgery
Translation:Humans
Cerebral saturation and cerebral blood flow in head-injured patients. Neurosurg Focus. 2012 Dec; 33(6):E12: 1; author reply E12: 1-2. Drummond JC, Patel PM. PMID: 23199424.

View in: PubMed Mentions: Fields:
Neu Neurosurgery
Translation:Humans
Caveolins: targeting pro-survival signaling in the heart and brain. Front Physiol. 2012; 3:393. Stary CM, Tsutsumi YM, Patel PM, Head BP, Patel HH, Roth DM. PMID: 23060817; PMCID: PMC3464704.

View in: PubMed Mentions: 25
Mitochondria-localized caveolin in adaptation to cellular stress and injury. FASEB J. 2012 Nov; 26(11):4637-49. Fridolfsson HN, Kawaraguchi Y, Ali SS, Panneerselvam M, Niesman IR, Finley JC, Kellerhals SE, Migita MY, Okada H, Moreno AL, Jennings M, Kidd MW, Bonds JA, Balijepalli RC, Ross RS, Patel PM, Miyanohara A, Chen Q, Lesnefsky EJ, Head BP, Roth DM, Insel PA, Patel HH. PMID: 22859372; PMCID: PMC4050367.

View in: PubMed Mentions: 44 Fields:
Bio Biology Phy Physiology
Translation:Humans Animals Cells
Propofol neurotoxicity is mediated by p75 neurotrophin receptor activation. Anesthesiology. 2012 Feb; 116(2):352-61. Pearn ML, Hu Y, Niesman IR, Patel HH, Drummond JC, Roth DM, Akassoglou K, Patel PM, Head BP. PMID: 22198221; PMCID: PMC3275822.

View in: PubMed Mentions: 62 Fields:
Ane Anesthesiology
Translation:Animals Cells
Volatile anesthetics protect cancer cells against tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis via caveolins. Anesthesiology. 2011 Sep; 115(3):499-508. Kawaraguchi Y, Horikawa YT, Murphy AN, Murray F, Miyanohara A, Ali SS, Head BP, Patel PM, Roth DM, Patel HH. PMID: 21862885; PMCID: PMC3162469.

View in: PubMed Mentions: 30 Fields:
Ane Anesthesiology
Translation:Humans Cells
Proscribing the use of albumin in the head-injured patient is not warranted. Anesth Analg. 2011 Aug; 113(2):426-7; author reply 427-8. Drummond JC, Patel PM, Lemkuil B. PMID: 21788329.

View in: PubMed Mentions: 2 Fields:
Ane Anesthesiology
Translation:Humans
Neuron-targeted caveolin-1 protein enhances signaling and promotes arborization of primary neurons. J Biol Chem. 2011 Sep 23; 286(38):33310-21. Head BP, Hu Y, Finley JC, Saldana MD, Bonds JA, Miyanohara A, Niesman IR, Ali SS, Murray F, Insel PA, Roth DM, Patel HH, Patel PM. PMID: 21799010; PMCID: PMC3190943.

View in: PubMed Mentions: 48 Fields:
Bio Biochemistry
Translation:Animals Cells
Role of decoy molecules in neuronal ischemic preconditioning. Life Sci. 2011 Apr 11; 88(15-16):670-4. Panneerselvam M, Patel PM, Roth DM, Kidd MW, Chin-Lee B, Head BP, Niesman IR, Inoue S, Patel HH, Davis DP. PMID: 21315738; PMCID: PMC3070046.

View in: PubMed Mentions: 7 Fields:
Bio Biochemistry Bio Biology Phy Physiology
Translation:Animals Cells
Isoflurane neurotoxicity is mediated by p75NTR-RhoA activation and actin depolymerization. Anesthesiology. 2011 Jan; 114(1):49-57. Lemkuil BP, Head BP, Pearn ML, Patel HH, Drummond JC, Patel PM. PMID: 21169791; PMCID: PMC3037980.

View in: PubMed Mentions: 56 Fields:
Ane Anesthesiology
Translation:Animals Cells
Loss of caveolin-1 accelerates neurodegeneration and aging. PLoS One. 2010 Dec 23; 5(12):e15697. Head BP, Peart JN, Panneerselvam M, Yokoyama T, Pearn ML, Niesman IR, Bonds JA, Schilling JM, Miyanohara A, Headrick J, Ali SS, Roth DM, Patel PM, Patel HH. PMID: 21203469; PMCID: PMC3009734.

View in: PubMed Mentions: 91 Fields:
Med Medicine (General)Sci Science
Translation:Animals Cells
Dark chocolate receptors: epicatechin-induced cardiac protection is dependent on delta-opioid receptor stimulation. Am J Physiol Heart Circ Physiol. 2010 Nov; 299(5):H1604-9. Panneerselvam M, Tsutsumi YM, Bonds JA, Horikawa YT, Saldana M, Dalton ND, Head BP, Patel PM, Roth DM, Patel HH. PMID: 20833967; PMCID: PMC2993198.

View in: PubMed Mentions: 18 Fields:
Car Cardiology Phy Physiology
Translation:Animals
Statins might contribute to postoperative delirium. Anesthesiology. 2010 Aug; 113(2):500-1. Drummond JC, Head BP, Patel PM. PMID: 20657207.

View in: PubMed Mentions: 2 Fields:
Ane Anesthesiology
Translation:Humans
Role of caveolin-3 and glucose transporter-4 in isoflurane-induced delayed cardiac protection. Anesthesiology. 2010 May; 112(5):1136-45. Tsutsumi YM, Kawaraguchi Y, Horikawa YT, Niesman IR, Kidd MW, Chin-Lee B, Head BP, Patel PM, Roth DM, Patel HH. PMID: 20418694; PMCID: PMC2860616.

View in: PubMed Mentions: 30 Fields:
Ane Anesthesiology
Translation:Animals Cells
At the sharp end of spines: anesthetic effects on synaptic remodeling in the developing brain. Anesthesiology. 2010 Mar; 112(3):521-3. Crosby G, Culley DJ, Patel PM. PMID: 20124984; PMCID: PMC2828506.

View in: PubMed Mentions: 5 Fields:
Ane Anesthesiology
Translation:Humans Cells
Intra-arterial injection in the rat brain: evaluation of steroids used for transforaminal epidurals. Spine (Phila Pa 1976). 2009 Jul 15; 34(16):1638-43. Dawley JD, Moeller-Bertram T, Wallace MS, Patel PM. PMID: 19770605.

View in: PubMed Mentions: 12 Fields:
Ort Orthopedics
Translation:Animals
Inhibition of p75 neurotrophin receptor attenuates isoflurane-mediated neuronal apoptosis in the neonatal central nervous system. Anesthesiology. 2009 Apr; 110(4):813-25. Head BP, Patel HH, Niesman IR, Drummond JC, Roth DM, Patel PM. PMID: 19293698; PMCID: PMC2767332.

View in: PubMed Mentions: 113 Fields:
Ane Anesthesiology
Translation:Animals Cells
Update on neonatal anesthetic neurotoxicity: insight into molecular mechanisms and relevance to humans. Anesthesiology. 2009 Apr; 110(4):703-8. Patel P, Sun L. PMID: 19276968; PMCID: PMC2737718.

View in: PubMed Mentions: 24 Fields:
Ane Anesthesiology
Translation:Humans Animals Cells
Cardiac-specific overexpression of caveolin-3 induces endogenous cardiac protection by mimicking ischemic preconditioning. Circulation. 2008 Nov 04; 118(19):1979-88. Tsutsumi YM, Horikawa YT, Jennings MM, Kidd MW, Niesman IR, Yokoyama U, Head BP, Hagiwara Y, Ishikawa Y, Miyanohara A, Patel PM, Insel PA, Patel HH, Roth DM. PMID: 18936328; PMCID: PMC2676165.

View in: PubMed Mentions: 72 Fields:
Car Cardiology Vas Vascular Diseases
Translation:Animals Cells
Journal-related and other special activities at the 2008 American Society of Anesthesiologists Annual Meeting. Anesthesiology. 2008 Sep; 109(3):365. Lerman J, Kharasch ED, Eisenach JC, Warner MA, Jevtovic-Todorovic V, Patel PM, Sun LS. PMID: 18754137.

View in: PubMed Mentions: 1 Fields:
Ane Anesthesiology
Effect of dexmedetomidine on cerebral blood flow velocity, cerebral metabolic rate, and carbon dioxide response in normal humans. Anesthesiology. 2008 Feb; 108(2):225-32. Drummond JC, Dao AV, Roth DM, Cheng CR, Atwater BI, Minokadeh A, Pasco LC, Patel PM. PMID: 18212567.

View in: PubMed Mentions: 37 Fields:
Ane Anesthesiology
Translation:Humans
Anesthetics and brain protection. Curr Opin Anaesthesiol. 2007 Oct; 20(5):395-9. Head BP, Patel P. PMID: 17873591.

View in: PubMed Mentions: 23 Fields:
Ane Anesthesiology
Translation:Humans
Caveolin-1 expression is essential for N-methyl-D-aspartate receptor-mediated Src and extracellular signal-regulated kinase 1/2 activation and protection of primary neurons from ischemic cell death. FASEB J. 2008 Mar; 22(3):828-40. Head BP, Patel HH, Tsutsumi YM, Hu Y, Mejia T, Mora RC, Insel PA, Roth DM, Drummond JC, Patel PM. PMID: 17905724.

View in: PubMed Mentions: 61 Fields:
Bio Biology Phy Physiology
Translation:Humans Animals Cells
Pathway and gene ontology based analysis of gene expression in a rat model of cerebral ischemic tolerance. Brain Res. 2007 Oct 26; 1177:103-23. Feng Z, Davis DP, Sásik R, Patel HH, Drummond JC, Patel PM. PMID: 17916339.

View in: PubMed Mentions: 19 Fields:
Bra Brain
Translation:Animals Cells
Mechanisms of cardiac protection from ischemia/reperfusion injury: a role for caveolae and caveolin-1. FASEB J. 2007 May; 21(7):1565-74. Patel HH, Tsutsumi YM, Head BP, Niesman IR, Jennings M, Horikawa Y, Huang D, Moreno AL, Patel PM, Insel PA, Roth DM. PMID: 17272740.

View in: PubMed Mentions: 67 Fields:
Bio Biology Phy Physiology
Translation:Animals Cells
Reevaluation of gray and white matter injury after spinal cord ischemia in rabbits. Anesthesiology. 2006 Aug; 105(2):305-12. Kurita N, Kawaguchi M, Kakimoto M, Yamamoto Y, Inoue S, Nakamura M, Konishi N, Patel PM, Furuya H. PMID: 16871064.

View in: PubMed Mentions: 3 Fields:
Ane Anesthesiology
Translation:Animals
The combination of isoflurane and caspase 8 inhibition results in sustained neuroprotection in rats subject to focal cerebral ischemia. Anesth Analg. 2006 May; 102(5):1548-55. Inoue S, Davis DP, Drummond JC, Cole DJ, Patel PM. PMID: 16632840.

View in: PubMed Mentions: 11 Fields:
Ane Anesthesiology
Translation:Animals
A phase 1 clinical trial of nerve growth factor gene therapy for Alzheimer disease. Nat Med. 2005 May; 11(5):551-5. Tuszynski MH, Thal L, Pay M, Salmon DP, U HS, Bakay R, Patel P, Blesch A, Vahlsing HL, Ho G, Tong G, Potkin SG, Fallon J, Hansen L, Mufson EJ, Kordower JH, Gall C, Conner J. PMID: 15852017.

View in: PubMed Mentions: 310 Fields:
Med Medicine (General)Mol Molecular Biology
Translation:Humans Cells CTClinical Trials
The role of nitric oxide synthase inhibition in the adverse effects of etomidate in the setting of focal cerebral ischemia in rats. Anesth Analg. 2005 Mar; 100(3):841-846. Drummond JC, McKay LD, Cole DJ, Patel PM. PMID: 15728077.

View in: PubMed Mentions: 9 Fields:
Ane Anesthesiology
Translation:Animals
Etomidate, transfusion, and vasospasm. J Neurosurg. 2005 Mar; 102(3):583-4; author reply 585-6. Drummond JC, Cole DJ, Patel PM. PMID: 15796403.

View in: PubMed Mentions: Fields:
Neu Neurosurgery
Translation:Animals
Neuroprotective effects of anesthetic agents. J Anesth. 2005; 19(2):150-6. Kawaguchi M, Furuya H, Patel PM. PMID: 15875133.

View in: PubMed Mentions: 51 Fields:
Ane Anesthesiology
Translation:Humans Animals
Combination of isoflurane and caspase inhibition reduces cerebral injury in rats subjected to focal cerebral ischemia. Anesthesiology. 2004 Jul; 101(1):75-81. Inoue S, Drummond JC, Davis DP, Cole DJ, Patel PM. PMID: 15220774.

View in: PubMed Mentions: 8 Fields:
Ane Anesthesiology
Translation:Animals Cells
No magic bullets: the ephemeral nature of anesthetic-mediated neuroprotection. Anesthesiology. 2004 May; 100(5):1049-51. Patel P. PMID: 15114198.

View in: PubMed Mentions: 3 Fields:
Ane Anesthesiology
Translation:Humans Animals
Effect of isoflurane on neuronal apoptosis in rats subjected to focal cerebral ischemia. Anesth Analg. 2004 Mar; 98(3):798-805, table of contents. Kawaguchi M, Drummond JC, Cole DJ, Kelly PJ, Spurlock MP, Patel PM. PMID: 14980940.

View in: PubMed Mentions: 29 Fields:
Ane Anesthesiology
Translation:Animals Cells
Ischemic preconditioning in the brain. Curr Opin Anaesthesiol. 2003 Oct; 16(5):447-52. Davis DP, Patel PM. PMID: 17021495.

View in: PubMed Mentions: 9 Fields:
Ane Anesthesiology
Efficacy and safety of desloratadine 5 mg once daily in the treatment of chronic idiopathic urticaria: a double-blind, randomized, placebo-controlled trial. J Am Acad Dermatol. 2003 Apr; 48(4):535-41. Monroe E, Finn A, Patel P, Guerrero R, Ratner P, Bernstein D, Desloratadine Uritcaria Study Group. PMID: 12664016.

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Der Dermatology
Translation:Humans CTClinical Trials
Isoflurane and pentobarbital reduce the frequency of transient ischemic depolarizations during focal ischemia in rats. Anesth Analg. 1998 Apr; 86(4):773-80. Patel PM, Drummond JC, Cole DJ, Kelly PJ, Watson M. PMID: 9539600.

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Ane Anesthesiology
Translation:Animals