-
Impaired immune responses in the airways are associated with poor outcome in critically ill COVID-19 patients. ERJ Open Res. 2024 Jul; 10(4).
Barnett CR, Krolikowski K, Postelnicu R, Mukherjee V, Sulaiman I, Chung M, Angel L, Tsay JJ, Wu BG, Yeung ST, Duerr R, Desvignes L, Khanna K, Li Y, Schluger R, Rafeq S, Collazo D, Kyeremateng Y, Amoroso N, Pradhan D, Das S, Evans L, Uyeki TM, Ghedin E, Silverman GJ, Segal LN, Brosnahan SB. PMID: 38978558; PMCID: PMC11228597.
View in:
PubMed Mentions:
-
Longitudinal study of immunity to SARS-CoV2 in ocrelizumab-treated MS patients up to 2 years after COVID-19 vaccination. Ann Clin Transl Neurol. 2024 Jul; 11(7):1750-1764.
Kister I, Curtin R, Piquet AL, Borko T, Pei J, Banbury BL, Bacon TE, Kim A, Tuen M, Velmurugu Y, Nyovanie S, Selva S, Samanovic MI, Mulligan MJ, Patskovsky Y, Priest J, Cabatingan M, Winger RC, Krogsgaard M, Silverman GJ. PMID: 38713096; PMCID: PMC11251481.
View in:
PubMed Mentions: Fields:
Translation:
HumansCellsPHPublic Health
-
The gut microbiome in systemic lupus erythematosus: lessons from rheumatic fever. Nat Rev Rheumatol. 2024 Mar; 20(3):143-157.
Silverman GJ, Azzouz DF, Gisch N, Amarnani A. PMID: 38321297.
View in:
PubMed Mentions:
4 Fields:
Translation:
Humans
-
Understanding the roles of the microbiome in autoimmune rheumatic diseases. Rheumatol Immunol Res. 2023 Dec; 4(4):177-187.
Amarnani A, Silverman GJ. PMID: 38125641; PMCID: PMC10729600.
View in:
PubMed Mentions:
2
-
Extracting Complementary and Integrative Health Approaches in Electronic Health Records. J Healthc Inform Res. 2023 Sep; 7(3):277-290.
Zhou H, Silverman G, Niu Z, Silverman J, Evans R, Austin R, Zhang R. PMID: 37637720; PMCID: PMC10449701.
View in:
PubMed Mentions:
1
-
Longitudinal gut microbiome analyses and blooms of pathogenic strains during lupus disease flares. Ann Rheum Dis. 2023 10; 82(10):1315-1327.
Azzouz DF, Chen Z, Izmirly PM, Chen LA, Li Z, Zhang C, Mieles D, Trujillo K, Heguy A, Pironti A, Putzel GG, Schwudke D, Fenyo D, Buyon JP, Alekseyenko AV, Gisch N, Silverman GJ. PMID: 37365013; PMCID: PMC10511964.
View in:
PubMed Mentions:
14 Fields:
Translation:
Humans
-
Pharmacologic inhibition of glycolysis prevents the development of lupus by altering the gut microbiome in mice. iScience. 2023 Jul 21; 26(7):107122.
Elshikha AS, Ge Y, Brown J, Kanda N, Zadeh M, Abboud G, Choi SC, Silverman G, Garrett TJ, Clapp WL, Mohamadzadeh M, Morel L. PMID: 37416482; PMCID: PMC10320500.
View in:
PubMed Mentions:
3
-
Hybrid and vaccine-induced immunity against SAR-CoV-2 in MS patients on different disease-modifying therapies. Ann Clin Transl Neurol. 2022 10; 9(10):1643-1659.
Kister I, Curtin R, Pei J, Perdomo K, Bacon TE, Voloshyna I, Kim J, Tardio E, Velmurugu Y, Nyovanie S, Valeria Calderon A, Dibba F, Stanzin I, Samanovic MI, Raut P, Raposo C, Priest J, Cabatingan M, Winger RC, Mulligan MJ, Patskovsky Y, Silverman GJ, Krogsgaard M. PMID: 36165097; PMCID: PMC9538694.
View in:
PubMed Mentions:
6 Fields:
Translation:
HumansCells
-
Sex-dependent Lupus Blautia (Ruminococcus) gnavus strain induction of zonulin-mediated intestinal permeability and autoimmunity. Front Immunol. 2022; 13:897971.
Silverman GJ, Deng J, Azzouz DF. PMID: 36032126; PMCID: PMC9405438.
View in:
PubMed Mentions:
14 Fields:
Translation:
HumansAnimalsCells
-
Predictors of Postacute Sequelae of COVID-19 Development and Rehabilitation: A Retrospective Study. Arch Phys Med Rehabil. 2022 10; 103(10):2001-2008.
Abdelwahab N, Ingraham NE, Nguyen N, Siegel L, Silverman G, Sahoo HS, Pakhomov S, Morse LR, Billings J, Usher MG, Melnik TE, Tignanelli CJ, Ikramuddin F. PMID: 35569640; PMCID: PMC9098397.
View in:
PubMed Mentions:
4 Fields:
Translation:
HumansCells
-
Faster B-cell repletion after anti-CD20 infusion in Black patients compared to white patients with neurologic diseases. Mult Scler Relat Disord. 2022 Jul; 63:103830.
Saidenberg L, Arbini AA, Silverman GJ, Lotan I, Cutter G, Kister I. PMID: 35490448.
View in:
PubMed Mentions:
9 Fields:
Translation:
HumansCells
-
Cellular and Humoral Immunity to SARS-CoV-2 Infection in Multiple Sclerosis Patients on Ocrelizumab and Other Disease-Modifying Therapies: A Multi-Ethnic Observational Study. Ann Neurol. 2022 06; 91(6):782-795.
Kister I, Patskovsky Y, Curtin R, Pei J, Perdomo K, Rimler Z, Voloshyna I, Samanovic MI, Cornelius AR, Velmurugu Y, Nyovanie S, Kim JJ, Tardio E, Bacon TE, Zhovtis Ryerson L, Raut P, Pedotti R, Hawker K, Raposo C, Priest J, Cabatingan M, Winger RC, Mulligan MJ, Krogsgaard M, Silverman GJ. PMID: 35289960; PMCID: PMC9082484.
View in:
PubMed Mentions:
14 Fields:
Translation:
HumansCells
-
Lupus gut microbiota transplants cause autoimmunity and inflammation. Clin Immunol. 2021 12; 233:108892.
Ma Y, Guo R, Sun Y, Li X, He L, Li Z, Silverman GJ, Chen G, Gao F, Yuan J, Wei Q, Li M, Lu L, Niu H. PMID: 34813937.
View in:
PubMed Mentions:
15 Fields:
Translation:
HumansAnimals
-
Editorial: Pathogens, Pathobionts, and Autoimmunity. Front Immunol. 2021; 12:752980.
Spatz LA, Silverman GJ, James JA. PMID: 34567014; PMCID: PMC8456017.
View in:
PubMed Mentions: Fields:
Translation:
HumansAnimalsCells
-
Tonic interferon restricts pathogenic IL-17-driven inflammatory disease via balancing the microbiome. Elife. 2021 08 11; 10.
Marié IJ, Brambilla L, Azzouz D, Chen Z, Baracho GV, Arnett A, Li HS, Liu W, Cimmino L, Chattopadhyay P, Silverman G, Watowich SS, Khor B, Levy DE. PMID: 34378531; PMCID: PMC8376249.
View in:
PubMed Mentions:
17 Fields:
Translation:
Animals
-
Autoantibody-mediated impairment of DNASE1L3 activity in sporadic systemic lupus erythematosus. J Exp Med. 2021 05 03; 218(5).
Hartl J, Serpas L, Wang Y, Rashidfarrokhi A, Perez OA, Sally B, Sisirak V, Soni C, Khodadadi-Jamayran A, Tsirigos A, Caiello I, Bracaglia C, Volpi S, Ghiggeri GM, Chida AS, Sanz I, Kim MY, Belmont HM, Silverman GJ, Clancy RM, Izmirly PM, Buyon JP, Reizis B. PMID: 33783474; PMCID: PMC8020718.
View in:
PubMed Mentions:
52 Fields:
Translation:
HumansAnimalsCells
-
Diversity of Functionally Distinct Clonal Sets of Human Conventional Memory B Cells That Bind Staphylococcal Protein A. Front Immunol. 2021; 12:662782.
Radke EE, Li Z, Hernandez DN, El Bannoudi H, Kosakovsky Pond SL, Shopsin B, Lopez P, Fenyö D, Silverman GJ. PMID: 33995388; PMCID: PMC8113617.
View in:
PubMed Mentions:
4 Fields:
Translation:
HumansCells
-
Could Compensatory Autoantibody Production Affect Rheumatoid Arthritis Etiopathogenesis? Arthritis Rheumatol. 2021 05; 73(5):728-730.
Silverman GJ. PMID: 33538128.
View in:
PubMed Mentions:
1 Fields:
Translation:
Humans
-
Blood clots and TAM receptor signalling in COVID-19 pathogenesis. Nat Rev Immunol. 2020 07; 20(7):395-396.
Lemke G, Silverman GJ. PMID: 32488201; PMCID: PMC7264968.
View in:
PubMed Mentions:
26 Fields:
Translation:
HumansAnimalsCellsPHPublic Health
-
Convergent Evolution of Neutralizing Antibodies to Staphylococcus aureus γ-Hemolysin C That Recognize an Immunodominant Primary Sequence-Dependent B-Cell Epitope. mBio. 2020 06 16; 11(3).
Hernandez DN, Tam K, Shopsin B, Radke EE, Law K, Cardozo T, Torres VJ, Silverman GJ. PMID: 32546616; PMCID: PMC7298706.
View in:
PubMed Mentions:
4 Fields:
Translation:
HumansAnimalsCells
-
Unbiased Identification of Immunogenic Staphylococcus aureus Leukotoxin B-Cell Epitopes. Infect Immun. 2020 03 23; 88(4).
Hernandez DN, Tam K, Shopsin B, Radke EE, Kolahi P, Copin R, Stubbe FX, Cardozo T, Torres VJ, Silverman GJ. PMID: 32014894; PMCID: PMC7093132.
View in:
PubMed Mentions:
3 Fields:
Translation:
AnimalsCells
-
Response to: 'The level of peripheral regulatory T cells is linked to changes in gut commensal microflora in patients with systemic lupus erythematosus' by Zhang et al and the phylogeny of a candidate pathobiont in lupus nephritis. Ann Rheum Dis. 2021 11; 80(11):e178.
Silverman GJ, Azzouz DF. PMID: 31732516.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansCells
-
Systemic Lupus Erythematosus and dysbiosis in the microbiome: cause or effect or both? Curr Opin Immunol. 2019 12; 61:80-85.
Silverman GJ, Azzouz DF, Alekseyenko AV. PMID: 31590039; PMCID: PMC6901743.
View in:
PubMed Mentions:
27 Fields:
Translation:
HumansAnimals
-
Protective effect of hydroxychloroquine on rheumatoid arthritis-associated atherosclerosis. Animal Model Exp Med. 2019 Jun; 2(2):98-106.
Shi N, Zhang S, Silverman G, Li M, Cai J, Niu H. PMID: 31392302; PMCID: PMC6600633.
View in:
PubMed Mentions:
20 Fields:
-
B1 B cell progenitors. Science. 2019 04 19; 364(6437):248.
Ghosn E, Dorshkind K, Herzenberg LA, Holodick N, Kantor A, Montecino-Rodriguez E, Rothstein TL, Silverman GJ, Yang Y, Yoder MC, Yoshimoto M. PMID: 31000655; PMCID: PMC7257805.
View in:
PubMed Mentions:
6 Fields:
Translation:
Cells
-
Tissue resident and follicular Treg cell differentiation is regulated by CRAC channels. Nat Commun. 2019 03 12; 10(1):1183.
Vaeth M, Wang YH, Eckstein M, Yang J, Silverman GJ, Lacruz RS, Kannan K, Feske S. PMID: 30862784; PMCID: PMC6414608.
View in:
PubMed Mentions:
27 Fields:
Translation:
HumansAnimalsCells
-
Lupus nephritis is linked to disease-activity associated expansions and immunity to a gut commensal. Ann Rheum Dis. 2019 07; 78(7):947-956.
Azzouz D, Omarbekova A, Heguy A, Schwudke D, Gisch N, Rovin BH, Caricchio R, Buyon JP, Alekseyenko AV, Silverman GJ. PMID: 30782585; PMCID: PMC6585303.
View in:
PubMed Mentions:
172 Fields:
Translation:
HumansCells
-
The microbiome in SLE pathogenesis. Nat Rev Rheumatol. 2019 02; 15(2):72-74.
Silverman GJ. PMID: 30607012.
View in:
PubMed Mentions:
31 Fields:
Translation:
HumansAnimals
-
Essential Domain-Dependent Roles Within Soluble IgG for in vivo Superantigen Properties of Staphylococcal Protein A: Resolving the B-Cell Superantigen Paradox. Front Immunol. 2018; 9:2011.
Ulloa-Morales AJ, Goodyear CS, Silverman GJ. PMID: 30283436; PMCID: PMC6156153.
View in:
PubMed Mentions:
12 Fields:
Translation:
AnimalsCells
-
Hierarchy of human IgG recognition within the Staphylococcus aureus immunome. Sci Rep. 2018 09 05; 8(1):13296.
Radke EE, Brown SM, Pelzek AJ, Fulmer Y, Hernandez DN, Torres VJ, Thomsen IP, Chiang WK, Miller AO, Shopsin B, Silverman GJ. PMID: 30185867; PMCID: PMC6125462.
View in:
PubMed Mentions:
23 Fields:
Translation:
HumansCells
-
The Microbiome and Systemic Lupus Erythematosus. N Engl J Med. 2018 06 07; 378(23):2236-2237.
Rosenbaum JT, Silverman GJ. PMID: 29874543.
View in:
PubMed Mentions:
12 Fields:
Translation:
Humans
-
Immune checkpoint inhibitors and the union of bugs against cancer. Kidney Int. 2018 05; 93(5):1030-1032.
Silverman GJ, Azzouz DF, Mor A. PMID: 29680016; PMCID: PMC6488224.
View in:
PubMed Mentions:
2 Fields:
Translation:
HumansAnimalsCells
-
Human Memory B Cells Targeting Staphylococcus aureus Exotoxins Are Prevalent with Skin and Soft Tissue Infection. mBio. 2018 03 13; 9(2).
Pelzek AJ, Shopsin B, Radke EE, Tam K, Ueberheide BM, Fenyö D, Brown SM, Li Q, Rubin A, Fulmer Y, Chiang WK, Hernandez DN, El Bannoudi H, Sause WE, Sommerfield A, Thomsen IP, Miller AO, Torres VJ, Silverman GJ. PMID: 29535203; PMCID: PMC5850327.
View in:
PubMed Mentions:
19 Fields:
Translation:
HumansCells
-
Autoimmune reactivity to malondialdehyde adducts in systemic lupus erythematosus is associated with disease activity and nephritis. Arthritis Res Ther. 2018 02 26; 20(1):36.
Hardt U, Larsson A, Gunnarsson I, Clancy RM, Petri M, Buyon JP, Silverman GJ, Svenungsson E, Grönwall C. PMID: 29482604; PMCID: PMC5827973.
View in:
PubMed Mentions:
12 Fields:
Translation:
Humans
-
Is Gut Microbial LPS a Potential Trigger of Juvenile Idiopathic Arthritis? J Rheumatol. 2017 11; 44(11):1569-1571.
Azzouz DF, Silverman GJ. PMID: 29093074.
View in:
PubMed Mentions:
1 Fields:
Translation:
Humans
-
Depressed serum IgM levels in SLE are restricted to defined subgroups. Clin Immunol. 2017 10; 183:304-315.
Grönwall C, Hardt U, Gustafsson JT, Elvin K, Jensen-Urstad K, Kvarnström M, Grosso G, Rönnelid J, Padykov L, Gunnarsson I, Silverman GJ, Svenungsson E. PMID: 28919518.
View in:
PubMed Mentions:
11 Fields:
Translation:
Humans
-
Autoreactivity to malondialdehyde-modifications in rheumatoid arthritis is linked to disease activity and synovial pathogenesis. J Autoimmun. 2017 Nov; 84:29-45.
Grönwall C, Amara K, Hardt U, Krishnamurthy A, Steen J, Engström M, Sun M, Ytterberg AJ, Zubarev RA, Scheel-Toellner D, Greenberg JD, Klareskog L, Catrina AI, Malmström V, Silverman GJ. PMID: 28647488.
View in:
PubMed Mentions:
25 Fields:
Translation:
HumansCells
-
Targeting the programmed cell death-1 pathway in rheumatoid arthritis. Autoimmun Rev. 2017 Aug; 16(8):767-773.
Sandigursky S, Silverman GJ, Mor A. PMID: 28572054; PMCID: PMC5596871.
View in:
PubMed Mentions:
12 Fields:
Translation:
HumansAnimalsCells
-
Persistence of Disease-Associated Anti-Citrullinated Protein Antibody-Expressing Memory B Cells in Rheumatoid Arthritis in Clinical Remission. Arthritis Rheumatol. 2017 06; 69(6):1176-1186.
Pelzek AJ, Grönwall C, Rosenthal P, Greenberg JD, McGeachy M, Moreland L, Rigby WFC, Silverman GJ. PMID: 28118534; PMCID: PMC5569882.
View in:
PubMed Mentions:
18 Fields:
Translation:
HumansCells
-
Unbiased RACE-Based Massive Parallel Surveys of Human IgA Antibody Repertoires. Methods Mol Biol. 2017; 1643:45-73.
El Bannoudi H, Anquetil C, Braunstein MJ, Pond SLK, Silverman GJ. PMID: 28667529.
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansCells
-
miRNAs Are Essential for the Regulation of the PI3K/AKT/FOXO Pathway and Receptor Editing during B Cell Maturation. Cell Rep. 2016 11 22; 17(9):2271-2285.
Coffre M, Benhamou D, Rieß D, Blumenberg L, Snetkova V, Hines MJ, Chakraborty T, Bajwa S, Jensen K, Chong MMW, Getu L, Silverman GJ, Blelloch R, Littman DR, Calado D, Melamed D, Skok JA, Rajewsky K, Koralov SB. PMID: 27880903; PMCID: PMC5679080.
View in:
PubMed Mentions:
23 Fields:
Translation:
AnimalsCells
-
Modulation of natural IgM autoantibodies to oxidative stress-related neo-epitopes on apoptotic cells in newborns of mothers with anti-Ro autoimmunity. J Autoimmun. 2016 09; 73:30-41.
Grönwall C, Clancy RM, Getu L, Lloyd KA, Siegel DL, Reed JH, Buyon JP, Silverman GJ. PMID: 27289167; PMCID: PMC5003717.
View in:
PubMed Mentions:
5 Fields:
Translation:
Humans
-
Role of Natural Autoantibodies in Ugandans With Rheumatic Heart Disease and HIV. EBioMedicine. 2016 Mar; 5:161-6.
Huck DM, Okello E, Mirembe G, Ssinabulya I, Zidar DA, Silverman GJ, Getu L, Nowacki AS, Calabrese LH, Salata RA, Longenecker CT. PMID: 27077123; PMCID: PMC4816839.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansCells
-
Anti-carbamylated Protein Antibody Levels Correlate with Anti-Sa (Citrullinated Vimentin) Antibody Levels in Rheumatoid Arthritis. J Rheumatol. 2016 Feb; 43(2):273-281.
Challener GJ, Jones JD, Pelzek AJ, Hamilton BJ, Boire G, de Brum-Fernandes AJ, Masetto A, Carrier N, Ménard HA, Silverman GJ, Rigby WFC. PMID: 26669911; PMCID: PMC4737983.
View in:
PubMed Mentions:
14 Fields:
Translation:
Humans
-
Assigning and visualizing germline genes in antibody repertoires. Philos Trans R Soc Lond B Biol Sci. 2015 Sep 05; 370(1676).
Frost SD, Murrell B, Hossain AS, Silverman GJ, Pond SL. PMID: 26194754; PMCID: PMC4528417.
View in:
PubMed Mentions:
13 Fields:
Translation:
Humans
-
Analysis of Programmed Death-1 in Patients with Psoriatic Arthritis. Inflammation. 2015 Aug; 38(4):1573-9.
Peled M, Strazza M, Azoulay-Alfaguter I, Silverman GJ, Scher JU, Mor A. PMID: 25663558.
View in:
PubMed Mentions:
19 Fields:
Translation:
HumansCells
-
Erratum to: Analysis of Programmed Death-1 in Patients with Psoriatic Arthritis. Inflammation. 2015 Aug; 38(4):1580.
Peled M, Strazza M, Azoulay-Alfaguter I, Silverman GJ, Scher JU, Mor A. PMID: 25847627.
View in:
PubMed Mentions:
1 Fields:
-
Efficacy and Safety of Tabalumab, an Anti-B-Cell-Activating Factor Monoclonal Antibody, in a Heterogeneous Rheumatoid Arthritis Population: Results From a Randomized, Placebo-Controlled, Phase 3 Trial (FLEX-O). J Clin Rheumatol. 2015 Aug; 21(5):231-8.
Genovese MC, Silverman GJ, Emery P, Gupta RC, Gill A, Veenhuizen M, Xie L, Komocsar WJ, Berclaz PY, Lee C. PMID: 26203826.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansCellsCTClinical Trials
-
Protective natural autoantibodies to apoptotic cells: evidence of convergent selection of recurrent innate-like clones. Ann N Y Acad Sci. 2015 Dec; 1362:164-75.
Silverman GJ. PMID: 25990717; PMCID: PMC4651665.
View in:
PubMed Mentions:
16 Fields:
Translation:
HumansAnimalsCells
-
T cell chemokine receptor patterns as pathogenic signatures in autoimmunity. Discov Med. 2015 Feb; 19(103):117-25.
Strazza M, Azoulay-Alfaguter I, Silverman GJ, Mor A. PMID: 25725226.
View in:
PubMed Mentions:
5 Fields:
Translation:
Humans
-
Programmed death-1 pathway in cancer and autoimmunity. Clin Immunol. 2014 Jul; 153(1):145-52.
Pedoeem A, Azoulay-Alfaguter I, Strazza M, Silverman GJ, Mor A. PMID: 24780173.
View in:
PubMed Mentions:
122 Fields:
Translation:
HumansAnimalsCells
-
Selection of apoptotic cell specific human antibodies from adult bone marrow. PLoS One. 2014; 9(4):e95999.
Grönwall C, Charles ED, Dustin LB, Rader C, Silverman GJ. PMID: 24760047; PMCID: PMC3997490.
View in:
PubMed Mentions:
2 Fields:
Translation:
HumansAnimalsCells
-
Relation of carotid plaque with natural IgM antibodies in patients with systemic lupus erythematosus. Clin Immunol. 2014 Jul; 153(1):1-7.
Grönwall C, Reynolds H, Kim JK, Buyon J, Goldberg JD, Clancy RM, Silverman GJ. PMID: 24704464; PMCID: PMC4068957.
View in:
PubMed Mentions:
11 Fields:
Translation:
Humans
-
Natural IgM: beneficial autoantibodies for the control of inflammatory and autoimmune disease. J Clin Immunol. 2014 Jul; 34 Suppl 1:S12-21.
Grönwall C, Silverman GJ. PMID: 24691998; PMCID: PMC4354681.
View in:
PubMed Mentions:
85 Fields:
Translation:
HumansAnimals
-
Rheumatoid arthritis clinical benefits from abatacept, cytokine blockers, and rituximab are all linked to modulation of memory B cell responses. J Rheumatol. 2014 May; 41(5):825-8.
Silverman GJ, Pelzek A. PMID: 24692519; PMCID: PMC4386843.
View in:
PubMed Mentions:
4 Fields:
Translation:
HumansCells
-
Protective autoantibodies in the rheumatic diseases: lessons for therapy. Nat Rev Rheumatol. 2013 May; 9(5):291-300.
Silverman GJ, Vas J, Grönwall C. PMID: 23507902.
View in:
PubMed Mentions:
23 Fields:
Translation:
HumansAnimals
-
Fundamental roles of the innate-like repertoire of natural antibodies in immune homeostasis. Front Immunol. 2013; 4:4.
Vas J, Grönwall C, Silverman GJ. PMID: 23386848; PMCID: PMC3564042.
View in:
PubMed Mentions:
28 Fields:
-
MAPK phosphatase-1 is required for regulatory natural autoantibody-mediated inhibition of TLR responses. Proc Natl Acad Sci U S A. 2012 Nov 27; 109(48):19745-50.
Grönwall C, Chen Y, Vas J, Khanna S, Thiel S, Corr M, Kono DH, Silverman GJ. PMID: 23139409; PMCID: PMC3511709.
View in:
PubMed Mentions:
22 Fields:
Translation:
AnimalsCells
-
Natural antibody to apoptotic cell membranes inhibits the proinflammatory properties of lupus autoantibody immune complexes. Arthritis Rheum. 2012 Oct; 64(10):3388-98.
Vas J, Grönwall C, Marshak-Rothstein A, Silverman GJ. PMID: 22577035; PMCID: PMC3462267.
View in:
PubMed Mentions:
42 Fields:
Translation:
AnimalsCells
-
In vivo VL-targeted microbial superantigen induced global shifts in the B cell repertoire. J Immunol. 2012 Jul 15; 189(2):850-9.
Grönwall C, Kosakovsky Pond SL, Young JA, Silverman GJ. PMID: 22696444; PMCID: PMC3598568.
View in:
PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
-
Protective Roles of Natural IgM Antibodies. Front Immunol. 2012; 3:66.
Grönwall C, Vas J, Silverman GJ. PMID: 22566947; PMCID: PMC3341951.
View in:
PubMed Mentions:
180 Fields:
-
Natural IgM in immune equilibrium and harnessing their therapeutic potential. J Immunol. 2012 Feb 01; 188(3):939-45.
Kaveri SV, Silverman GJ, Bayry J. PMID: 22262757; PMCID: PMC3266110.
View in:
PubMed Mentions:
68 Fields:
Translation:
HumansAnimalsCells
-
IgM autoantibodies to distinct apoptosis-associated antigens correlate with protection from cardiovascular events and renal disease in patients with SLE. Clin Immunol. 2012 Mar; 142(3):390-8.
Grönwall C, Akhter E, Oh C, Burlingame RW, Petri M, Silverman GJ. PMID: 22297166; PMCID: PMC3632049.
View in:
PubMed Mentions:
59 Fields:
Translation:
Humans
-
Naturally occurring autoantibodies to apoptotic cells. Adv Exp Med Biol. 2012; 750:14-26.
Elkon KB, Silverman GJ. PMID: 22903663.
View in:
PubMed Mentions:
20 Fields:
Translation:
HumansAnimalsCells
-
Inflammation and autoantibody markers identify rheumatoid arthritis patients with enhanced clinical benefit following rituximab treatment. Arthritis Rheum. 2011 Dec; 63(12):3681-91.
Lal P, Su Z, Holweg CT, Silverman GJ, Schwartzman S, Kelman A, Read S, Spaniolo G, Monroe JG, Behrens TW, Townsend MJ. PMID: 22127691.
View in:
PubMed Mentions:
32 Fields:
Translation:
HumansCTClinical Trials
-
Co-opting endogenous immunoglobulin for the regulation of inflammation and osteoclastogenesis in humans and mice. Arthritis Rheum. 2011 Dec; 63(12):3897-907.
MacLellan LM, Montgomery J, Sugiyama F, Kitson SM, Thümmler K, Silverman GJ, Beers SA, Nibbs RJ, McInnes IB, Goodyear CS. PMID: 22127707; PMCID: PMC3598489.
View in:
PubMed Mentions:
13 Fields:
Translation:
HumansAnimalsCells
-
WASp-deficient B cells play a critical, cell-intrinsic role in triggering autoimmunity. J Exp Med. 2011 Sep 26; 208(10):2033-42.
Becker-Herman S, Meyer-Bahlburg A, Schwartz MA, Jackson SW, Hudkins KL, Liu C, Sather BD, Khim S, Liggitt D, Song W, Silverman GJ, Alpers CE, Rawlings DJ. PMID: 21875954; PMCID: PMC3182055.
View in:
PubMed Mentions:
97 Fields:
Translation:
HumansAnimalsCells
-
Development of anti-CD20 therapy for multiple sclerosis. Exp Cell Res. 2011 May 15; 317(9):1312-8.
Bartok B, Silverman GJ. PMID: 21510932; PMCID: PMC3266104.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansAnimalsCells
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Regulatory natural autoantibodies to apoptotic cells: pallbearers and protectors. Arthritis Rheum. 2011 Mar; 63(3):597-602.
Silverman GJ. PMID: 21360488; PMCID: PMC3056121.
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19 Fields:
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HumansCells
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Rethinking the red wolf disease: does Protein S suppress systemic lupus erythematosus clinical activity? Arthritis Res Ther. 2010; 12(5):144.
Silverman GJ. PMID: 21067626; PMCID: PMC2991027.
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2 Fields:
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HumansAnimals
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Natural autoantibodies to apoptotic cell membranes regulate fundamental innate immune functions and suppress inflammation. Discov Med. 2009 Oct; 8(42):151-6.
Silverman GJ, Grönwall C, Vas J, Chen Y. PMID: 19833064.
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22 Fields:
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HumansAnimalsCells
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Endosomal TLR signaling is required for anti-nucleic acid and rheumatoid factor autoantibodies in lupus. Proc Natl Acad Sci U S A. 2009 Jul 21; 106(29):12061-6.
Kono DH, Haraldsson MK, Lawson BR, Pollard KM, Koh YT, Du X, Arnold CN, Baccala R, Silverman GJ, Beutler BA, Theofilopoulos AN. PMID: 19574451; PMCID: PMC2715524.
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95 Fields:
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AnimalsCells
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Regulation of dendritic cells and macrophages by an anti-apoptotic cell natural antibody that suppresses TLR responses and inhibits inflammatory arthritis. J Immunol. 2009 Jul 15; 183(2):1346-59.
Chen Y, Khanna S, Goodyear CS, Park YB, Raz E, Thiel S, Grönwall C, Vas J, Boyle DL, Corr M, Kono DH, Silverman GJ. PMID: 19564341; PMCID: PMC2713016.
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92 Fields:
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AnimalsCells
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IgM antibodies to apoptosis-associated determinants recruit C1q and enhance dendritic cell phagocytosis of apoptotic cells. J Immunol. 2009 May 15; 182(10):6031-43.
Chen Y, Park YB, Patel E, Silverman GJ. PMID: 19414754; PMCID: PMC4428684.
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131 Fields:
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AnimalsCells
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Pathogenic natural antibodies recognizing annexin IV are required to develop intestinal ischemia-reperfusion injury. J Immunol. 2009 May 01; 182(9):5363-73.
Kulik L, Fleming SD, Moratz C, Reuter JW, Novikov A, Chen K, Andrews KA, Markaryan A, Quigg RJ, Silverman GJ, Tsokos GC, Holers VM. PMID: 19380783; PMCID: PMC2820395.
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72 Fields:
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HumansAnimalsCells
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Chronic lymphocytic leukemia cells recognize conserved epitopes associated with apoptosis and oxidation. Mol Med. 2008 Nov-Dec; 14(11-12):665-74.
Catera R, Silverman GJ, Hatzi K, Seiler T, Didier S, Zhang L, Hervé M, Meffre E, Oscier DG, Vlassara H, Scofield RH, Chen Y, Allen SL, Kolitz J, Rai KR, Chu CC, Chiorazzi N. PMID: 19009014; PMCID: PMC2582860.
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93 Fields:
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HumansCells
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Phage-display methodology for the study of protein-protein interactions: stage 1, generating libraries. CSH Protoc. 2008 Aug 01; 2008:pdb.prot5020.
Goodyear CS, Silverman GJ. PMID: 21356886.
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Phage-display methodology for the study of protein-protein interactions: stage 2, panning. CSH Protoc. 2008 Aug 01; 2008:pdb.prot5021.
Goodyear CS, Silverman GJ. PMID: 21356887.
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Phage-display methodology for the study of protein-protein interactions: stage 3, binding analysis. CSH Protoc. 2008 Aug 01; 2008:pdb.prot5022.
Goodyear CS, Silverman GJ. PMID: 21356888.
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Phage-display methodology for the study of protein-protein interactions: overview. CSH Protoc. 2008 Aug 01; 2008:pdb.top48.
Goodyear CS, Silverman GJ. PMID: 21356898.
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Understanding the mechanistic basis in rheumatoid arthritis for clinical response to anti-CD20 therapy: the B-cell roadblock hypothesis. Immunol Rev. 2008 Jun; 223:175-85.
Silverman GJ, Boyle DL. PMID: 18613836.
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PubMed Mentions:
20 Fields:
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HumansAnimalsCells
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Genetic imprinting of autoantibody repertoires in systemic lupus erythematosus patients. Clin Exp Immunol. 2008 Jul; 153(1):102-16.
Silverman GJ, Srikrishnan R, Germar K, Goodyear CS, Andrews KA, Ginzler EM, Tsao BP. PMID: 18510544; PMCID: PMC2432104.
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PubMed Mentions:
29 Fields:
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Humans
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Therapeutic potential (2). Lupus. 2008 Mar; 17(3):262-5.
Silverman GJ, Linnik MD. PMID: 18372374.
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HumansAnimals
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Quantitation of DNA and RNA. CSH Protoc. 2007 Nov 01; 2007:pdb.ip47.
Barbas CF, Burton DR, Scott JK, Silverman GJ. PMID: 21356961.
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18
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B cell modulation in rheumatology. Curr Opin Pharmacol. 2007 Aug; 7(4):426-33.
Silverman GJ, Khanna S. PMID: 17625968; PMCID: PMC2693398.
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PubMed Mentions:
2 Fields:
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HumansAnimalsCells
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Cutting Edge: Bim is required for superantigen-mediated B cell death. J Immunol. 2007 Mar 01; 178(5):2636-40.
Goodyear CS, Corr M, Sugiyama F, Boyle DL, Silverman GJ. PMID: 17312102.
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16 Fields:
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AnimalsCells
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Anti-CD20 therapy and autoimmune disease: therapeutic opportunities and evolving insights. Front Biosci. 2007 Jan 01; 12:2194-206.
Silverman GJ. PMID: 17127456.
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PubMed Mentions:
5 Fields:
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HumansCells
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Staphylococcus aureus protein A binding to von Willebrand factor A1 domain is mediated by conserved IgG binding regions. FEBS J. 2006 Nov; 273(21):4831-41.
O'Seaghdha M, van Schooten CJ, Kerrigan SW, Emsley J, Silverman GJ, Cox D, Lenting PJ, Foster TJ. PMID: 16999823.
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PubMed Mentions:
49 Fields:
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HumansCells
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Alternative and classical NF-kappa B signaling retain autoreactive B cells in the splenic marginal zone and result in lupus-like disease. Immunity. 2006 Sep; 25(3):403-15.
Enzler T, Bonizzi G, Silverman GJ, Otero DC, Widhopf GF, Anzelon-Mills A, Rickert RC, Karin M. PMID: 16973390.
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PubMed Mentions:
78 Fields:
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AnimalsCells
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Therapeutic B cell depletion and regeneration in rheumatoid arthritis: emerging patterns and paradigms. Arthritis Rheum. 2006 Aug; 54(8):2356-67.
Silverman GJ. PMID: 16868991.
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PubMed Mentions:
14 Fields:
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HumansCells
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Confounding B-cell defences: lessons from a staphylococcal superantigen. Nat Rev Immunol. 2006 Jun; 6(6):465-75.
Silverman GJ, Goodyear CS. PMID: 16724100.
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PubMed Mentions:
83 Fields:
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HumansAnimalsCells
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Temporal and dose-dependent relationships between in vivo B cell receptor-targeted proliferation and deletion-induced by a microbial B cell toxin. J Immunol. 2006 Feb 15; 176(4):2262-71.
Goodyear CS, Sugiyama F, Silverman GJ. PMID: 16455982.
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PubMed Mentions:
12 Fields:
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AnimalsCells
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Blocking the alpha 4 integrin-paxillin interaction selectively impairs mononuclear leukocyte recruitment to an inflammatory site. J Clin Invest. 2006 Mar; 116(3):715-23.
Féral CC, Rose DM, Han J, Fox N, Silverman GJ, Kaushansky K, Ginsberg MH. PMID: 16470243; PMCID: PMC1361348.
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PubMed Mentions:
33 Fields:
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AnimalsCells
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Prevention and reversal of nephritis in MRL/lpr mice with a single injection of C-reactive protein. Arthritis Rheum. 2006 Jan; 54(1):325-35.
Rodriguez W, Mold C, Marnell LL, Hutt J, Silverman GJ, Tran D, Du Clos TW. PMID: 16385552.
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35 Fields:
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Animals
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Targeting of B cells in SLE: rationale and therapeutic opportunities. Bull NYU Hosp Jt Dis. 2006; 64(1-2):51-6.
Silverman GJ. PMID: 17121490.
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PubMed Mentions:
5 Fields:
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HumansAnimalsCells
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Germinal center exclusion of autoreactive B cells is defective in human systemic lupus erythematosus. J Clin Invest. 2005 Nov; 115(11):3205-16.
Cappione A, Anolik JH, Pugh-Bernard A, Barnard J, Dutcher P, Silverman G, Sanz I. PMID: 16211091; PMCID: PMC1242189.
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PubMed Mentions:
169 Fields:
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HumansCells
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Bacterial cell wall-expressed protein A triggers supraclonal B-cell responses upon in vivo infection with Staphylococcus aureus. Microbes Infect. 2005 Dec; 7(15):1501-11.
Palmqvist N, Silverman GJ, Josefsson E, Tarkowski A. PMID: 16039897.
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13 Fields:
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AnimalsCells
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Natural antibodies and the autoimmunity of atherosclerosis. Springer Semin Immunopathol. 2005 Mar; 26(4):385-404.
Binder CJ, Silverman GJ. PMID: 15609021.
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72 Fields:
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HumansAnimalsCells
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B cell superantigens: a microbe's answer to innate-like B cells and natural antibodies. Springer Semin Immunopathol. 2005 Mar; 26(4):463-84.
Goodyear CS, Silverman GJ. PMID: 15633015.
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PubMed Mentions:
18 Fields:
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HumansAnimalsCells
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Anti-CD20 therapy in systemic lupus erythematosus: a step closer to the clinic. Arthritis Rheum. 2005 Feb; 52(2):371-7.
Silverman GJ. PMID: 15692969.
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PubMed Mentions:
3 Fields:
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Humans
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On the mechanism of staphylococcal protein A immunomodulation. Transfusion. 2005 Feb; 45(2):274-80.
Silverman GJ, Goodyear CS, Siegel DL. PMID: 15660839.
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10 Fields:
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HumansCells
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Apoptotic cells with oxidation-specific epitopes are immunogenic and proinflammatory. J Exp Med. 2004 Dec 06; 200(11):1359-70.
Chang MK, Binder CJ, Miller YI, Subbanagounder G, Silverman GJ, Berliner JA, Witztum JL. PMID: 15583011; PMCID: PMC2211955.
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145 Fields:
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AnimalsCells
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Staphylococcal toxin induced preferential and prolonged in vivo deletion of innate-like B lymphocytes. Proc Natl Acad Sci U S A. 2004 Aug 03; 101(31):11392-7.
Goodyear CS, Silverman GJ. PMID: 15273292; PMCID: PMC509211.
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PubMed Mentions:
41 Fields:
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AnimalsCells
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A recombinant antibody increases cardiac contractility by mimicking phospholamban phosphorylation. FASEB J. 2004 Aug; 18(11):1312-4.
Meyer M, Belke DD, Trost SU, Swanson E, Dieterle T, Scott B, Cary SP, Ho P, Bluhm WF, McDonough PM, Silverman GJ, Dillmann WH. PMID: 15180962.
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PubMed Mentions:
12 Fields:
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HumansAnimalsCells
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In vivo VL-targeted activation-induced apoptotic supraclonal deletion by a microbial B cell toxin. J Immunol. 2004 Mar 01; 172(5):2870-7.
Goodyear CS, Narita M, Silverman GJ. PMID: 14978088.
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PubMed Mentions:
12 Fields:
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AnimalsCells
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Roles of B cells in rheumatoid arthritis. Arthritis Res Ther. 2003; 5 Suppl 4:S1-6.
Silverman GJ, Carson DA. PMID: 15180890; PMCID: PMC2833442.
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72 Fields:
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HumansAnimalsCells
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The autoreactivity of anti-phosphorylcholine antibodies for atherosclerosis-associated neo-antigens and apoptotic cells. J Immunol. 2003 Jun 15; 170(12):6151-7.
Shaw PX, Goodyear CS, Chang MK, Witztum JL, Silverman GJ. PMID: 12794145.
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60 Fields:
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AnimalsCells
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Rituximab therapy and autoimmune disorders: prospects for anti-B cell therapy. Arthritis Rheum. 2003 Jun; 48(6):1484-92.
Silverman GJ, Weisman S. PMID: 12794814.
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74 Fields:
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HumansAnimalsCells
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Pneumococcal vaccination decreases atherosclerotic lesion formation: molecular mimicry between Streptococcus pneumoniae and oxidized LDL. Nat Med. 2003 Jun; 9(6):736-43.
Binder CJ, Hörkkö S, Dewan A, Chang MK, Kieu EP, Goodyear CS, Shaw PX, Palinski W, Witztum JL, Silverman GJ. PMID: 12740573.
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Death by a B cell superantigen: In vivo VH-targeted apoptotic supraclonal B cell deletion by a Staphylococcal Toxin. J Exp Med. 2003 May 05; 197(9):1125-39.
Goodyear CS, Silverman GJ. PMID: 12719481; PMCID: PMC2193973.
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PubMed Mentions:
100 Fields:
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AnimalsCells
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Development of functional human monoclonal single-chain variable fragment antibody against HIV-1 from human cervical B cells. Hybrid Hybridomics. 2003 Apr; 22(2):97-108.
Berry JD, Rutherford J, Silverman GJ, Kaul R, Elia M, Gobuty S, Fuller R, Plummer FA, Barbas CF. PMID: 12831535.
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PubMed Mentions:
5 Fields:
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HumansCells
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Mucosal plasma cell repertoire during HIV-1 infection. J Immunol. 2002 Oct 01; 169(7):4008-16.
Scamurra RW, Nelson DB, Lin XM, Miller DJ, Silverman GJ, Kappel T, Thurn JR, Lorenz E, Kulkarni-Narla A, Janoff EN. PMID: 12244203.
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17 Fields:
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HumansCells
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A model B-cell superantigen and the immunobiology of B lymphocytes. Clin Immunol. 2002 Feb; 102(2):117-34.
Silverman GJ, Goodyear CS. PMID: 11846453.
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PubMed Mentions:
20 Fields:
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HumansAnimalsCells
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Adoptive transfer of a superantigen-induced hole in the repertoire of natural IgM-secreting cells. Cell Immunol. 2001 Apr 10; 209(1):76-80.
Silverman GJ. PMID: 11414738.
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PubMed Mentions:
5 Fields:
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AnimalsCells
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A B cell superantigen-induced persistent "Hole" in the B-1 repertoire. J Exp Med. 2000 Jul 03; 192(1):87-98.
Silverman GJ, Cary SP, Dwyer DC, Luo L, Wagenknecht R, Curtiss VE. PMID: 10880529; PMCID: PMC1887708.
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PubMed Mentions:
27 Fields:
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HumansAnimalsCells
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The dual phases of the response to neonatal exposure to a VH family-restricted staphylococcal B cell superantigen. J Immunol. 1998 Nov 15; 161(10):5720-32.
Silverman GJ, Nayak JV, Warnatz K, Hajjar FF, Cary S, Tighe H, Curtiss VE. PMID: 9820554.
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PubMed Mentions:
9 Fields:
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AnimalsCells
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B-cell superantigens. Immunol Today. 1997 Aug; 18(8):379-86.
Silverman GJ. PMID: 9267080.
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PubMed Mentions:
14 Fields:
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HumansAnimalsCells
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B-cell superantigens: molecular and cellular implications. Int Rev Immunol. 1997; 14(4):259-90.
Silverman GJ, Nayak JV, La Cava A. PMID: 9186781.
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HumansAnimalsCells