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Michael Kalichman

Title(s)Adjunct Professor, Pathology
SchoolHealth Sciences
Phone858-822-2027
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    Collapse Overview 
    Collapse Overview
    Kalichman has taught research ethics for nearly 25 years. He is founding director of the UC San Diego Research Ethics Program since 1997, the San Diego Research Ethics Consortium since 2006, and the ethics service for the NIH CTSA-funded Clinical and Translational Research Institute since 2010. In addition, Kalichman is co-founding director for the Center for Ethics in Science and Technology since 2004. Kalichman has taught train-the-trainer, research ethics workshops throughout the U.S. and for groups and institutions in Central America, Africa, and Asia. In 1999, with support from the Office of Research Integrity, he created one of the first online resources for the teaching of research ethics (http://research-ethics.net). He leads NIH- and NSF-funded research on the goals, content, and methods for teaching research ethics. Internationally, he has had significant roles in a collaboration between the AAAS and the China Association of Science and Technology (CAST), co-chairing the working group for RCR education at the 2010 Singapore meeting of the World Conference on Research Integrity, and assisting Korean leaders in setting a national research ethics agenda.

    Collapse Research 
    Collapse Research Activities and Funding
    Characterizing Privacy Perceptions and Risks in HIV Molecular Epidemiology
    NIH/NIAID R21AI108351Jun 1, 2014 - May 31, 2016
    Role: Principal Investigator
    Standards of Scientific Conduct
    NIH/NINR R01NR009962Sep 1, 2007 - May 31, 2010
    Role: Principal Investigator
    TRAINING IN CLINICAL RESEARCH ETHICS
    NIH/NIAID K01AI001591Aug 1, 2001 - Jul 31, 2007
    Role: Principal Investigator
    LOCAL ANESTHETIC NEUROTOXICITY IN THE SPINAL CORD
    NIH/NINDS R29NS024833Apr 1, 1987 - Jun 30, 1993
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Schairer CE, Mehta SR, Vinterbo SA, Hoenigl M, Kalichman M, Little SJ. Trust and Expectations of Researchers and Public Health Departments for the Use of HIV Molecular Epidemiology. AJOB Empir Bioeth. 2019 May 03; 1-13. PMID: 31050604.
      View in: PubMed
    2. Schairer C, Mehta SR, Vinterbo SA, Hoenigl M, Kalichman M, Little S. Perceptions of molecular epidemiology studies of HIV among stakeholders. J Public Health Res. 2017 Dec 13; 6(3):992. PMID: 29291190.
      View in: PubMed
    3. Al-Khatib A, Kalichman M. Responsible Conduct of Human Subjects Research in Islamic Communities. Sci Eng Ethics. 2017 Nov 10. PMID: 29127672.
      View in: PubMed
    4. Adelman Z, Akbari O, Bauer J, Bier E, Bloss C, Carter SR, Callender C, Denis AC, Cowhey P, Dass B, Delborne J, Devereaux M, Ellsworth P, Friedman RM, Gantz V, Gibson C, Hay BA, Hoddle M, James AA, James S, Jorgenson L, Kalichman M, Marshall J, McGinnis W, Newman J, Pearson A, Quemada H, Rudenko L, Shelton A, Vinetz JM, Weisman J, Wong B, Wozniak C. Rules of the road for insect gene drive research and testing. Nat Biotechnol. 2017 08 08; 35(8):716-718. PMID: 28787415.
      View in: PubMed
    5. Kalichman MW, Plemmons DK. Intervention to Promote Responsible Conduct of Research Mentoring. Sci Eng Ethics. 2018 04; 24(2):699-725. PMID: 28608033.
      View in: PubMed
    6. Plemmons DK, Kalichman MW. Mentoring for Responsible Research: The Creation of a Curriculum for Faculty to Teach RCR in the Research Environment. Sci Eng Ethics. 2018 02; 24(1):207-226. PMID: 28281158.
      View in: PubMed
    7. Kalichman M. Responsible Conduct of Research Education (What, Why, and Does It Work?). Acad Med. 2016 Dec; 91(12):e10. PMID: 27749309.
      View in: PubMed
    8. Nebeker C, Kalichman M, Talavera A, Elder J. Training in Research Ethics and Standards for Community Health Workers and Promotores Engaged in Latino Health Research. Hastings Cent Rep. 2015 Jul-Aug; 45(4):20-7. PMID: 26152386.
      View in: PubMed
    9. Kalichman MW, Plemmons DK. Research Agenda: The Effects of Responsible-Conduct-of-Research Training on Attitudes. J Empir Res Hum Res Ethics. 2015 Dec; 10(5):457-9. PMID: 25752981.
      View in: PubMed
    10. Kalichman M. A Modest Proposal to Move RCR Education Out of the Classroom and into Research. J Microbiol Biol Educ. 2014 Dec; 15(2):93-5. PMID: 25574254; PMCID: PMC4278527.
    11. Kalichman M, Sweet M, Plemmons D. Standards of Scientific Conduct: Disciplinary Differences. Sci Eng Ethics. 2015 Oct; 21(5):1085-93. PMID: 25256408; PMCID: PMC4375091 [Available on 10/01/16].
    12. Taras HL, Kalichman MW, Schulteis G, Dumbauld J, Bell Y, Seligman FF, West KD. Soliciting views of various communities on health research: a prelude to engagement in specific research projects. Health Expect. 2015 Dec; 18(6):2753-63. PMID: 25103450; PMCID: PMC4320671.
    13. Kalichman M. Rescuing responsible conduct of research (RCR) education. Account Res. 2014; 21(1):68-83. PMID: 24073608.
      View in: PubMed
    14. Kalichman M, Sweet M, Plemmons D. Standards of scientific conduct: are there any? Sci Eng Ethics. 2014 Dec; 20(4):885-96. PMID: 24337932.
      View in: PubMed
    15. Dumbauld J, Kalichman M, Bell Y, Dagnino C, Taras HL. Case study in designing a research fundamentals curriculum for community health workers: a university-community clinic collaboration. Health Promot Pract. 2014 Jan; 15(1):79-85. PMID: 24121537; PMCID: PMC4034738.
    16. Plemmons DK, Kalichman MW. Reported goals of instructors of responsible conduct of research for teaching of skills. J Empir Res Hum Res Ethics. 2013 Apr; 8(2):95-103. PMID: 23651933; PMCID: PMC3705638.
    17. Kalichman M. A brief history of RCR education. Account Res. 2013; 20(5-6):380-94. PMID: 24028484.
      View in: PubMed
    18. Devereaux M, Kalichman M. ESCRO committees--not dead yet. Am J Bioeth. 2013; 13(1):59-60. PMID: 23311849; PMCID: PMC3594697.
    19. Kalichman M, Plemmons D, Bird SJ. Editors' overview: Neuroethics: many voices and many stories. Sci Eng Ethics. 2012 Sep; 18(3):423-32. PMID: 23054674; PMCID: PMC3483404.
    20. Kalichman MW. Overview: underserved areas of education in the responsible conduct of research: authorship. Sci Eng Ethics. 2011 Jun; 17(2):335-9. PMID: 21611821; PMCID: PMC3428198.
    21. Blight A, Curt A, Ditunno JF, Dobkin B, Ellaway P, Fawcett J, Fehlings M, Grossman RG, Lammertse DP, Privat A, Steeves J, Tuszynski M, Kalichman M, Guest JD. Position statement on the sale of unproven cellular therapies for spinal cord injury: the international campaign for cures of spinal cord injury paralysis. Spinal Cord. 2009 Sep; 47(9):713-4. PMID: 19417762.
      View in: PubMed
    22. Schwartz PH, Kalichman MW. Ethical challenges to cell-based interventions for the central nervous system: some recommendations for clinical trials and practice. Am J Bioeth. 2009 May; 9(5):41-3. PMID: 19396684.
      View in: PubMed
    23. Kalichman M. Evidence-based research ethics. Am J Bioeth. 2009; 9(6-7):85-7. PMID: 19998132; PMCID: PMC3586321.
    24. Kalichman MW, Plemmons DK. Reported goals for responsible conduct of research courses. Acad Med. 2007 Sep; 82(9):846-52. PMID: 17726389.
      View in: PubMed
    25. Kalichman MW. Responding to challenges in educating for the responsible conduct of research. Acad Med. 2007 Sep; 82(9):870-5. PMID: 17726394.
      View in: PubMed
    26. Powell ST, Allison MA, Kalichman MW. Effectiveness of a responsible conduct of research course: a preliminary study. Sci Eng Ethics. 2007 Jun; 13(2):249-64. PMID: 17717736.
      View in: PubMed
    27. Plemmons DK, Kalichman MW. Reported Goals For Knowledge to be Learned in Responsible Conduct of Research Courses. J Empir Res Hum Res Ethics. 2007 Jun; 2(2):57-66. PMID: 19385796.
      View in: PubMed
    28. Lammertse D, Tuszynski MH, Steeves JD, Curt A, Fawcett JW, Rask C, Ditunno JF, Fehlings MG, Guest JD, Ellaway PH, Kleitman N, Blight AR, Dobkin BH, Grossman R, Katoh H, Privat A, Kalichman M. Guidelines for the conduct of clinical trials for spinal cord injury as developed by the ICCP panel: clinical trial design. Spinal Cord. 2007 Mar; 45(3):232-42. PMID: 17179970.
      View in: PubMed
    29. Tuszynski MH, Steeves JD, Fawcett JW, Lammertse D, Kalichman M, Rask C, Curt A, Ditunno JF, Fehlings MG, Guest JD, Ellaway PH, Kleitman N, Bartlett PF, Blight AR, Dietz V, Dobkin BH, Grossman R, Privat A. Guidelines for the conduct of clinical trials for spinal cord injury as developed by the ICCP Panel: clinical trial inclusion/exclusion criteria and ethics. Spinal Cord. 2007 Mar; 45(3):222-31. PMID: 17179971.
      View in: PubMed
    30. Plemmons DK, Brody SA, Kalichman MW. Student perceptions of the effectiveness of education in the responsible conduct of research. Sci Eng Ethics. 2006 Jul; 12(3):571-82. PMID: 16909159.
      View in: PubMed
    31. Snyder EY, Hinman LM, Kalichman MW. Can science resolve the ethical impasse in stem cell research? Nat Biotechnol. 2006 Apr; 24(4):397-400. PMID: 16601717.
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    32. Yücel YH, Gupta N, Zhang Q, Mizisin AP, Kalichman MW, Weinreb RN. Memantine protects neurons from shrinkage in the lateral geniculate nucleus in experimental glaucoma. Arch Ophthalmol. 2006 Feb; 124(2):217-25. PMID: 16476892.
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    33. Kalichman MW, Hinman LM. Consensus and the search for pluripotent stem cells. Stem Cell Rev. 2005 Dec; 1(4):287-9. PMID: 17142868.
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    34. Kalichman MW, Hinman LM, Snyder EY. Exploring common ground in the stem cell ethical debate--a perspective for scientists: introduction to this special issue of stem cell reviews. Stem Cell Rev. 2005 Dec; 1(4):285-6. PMID: 17142867.
      View in: PubMed
    35. Kalichman M. Use and abuse of the internet for teaching research ethics--commentary on "Misconceptions and realities about teaching online". Sci Eng Ethics. 2005 Jul; 11(3):341-5. PMID: 16190275.
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    36. Kalichman M. Ethical decision-making in research: identifying all competing interests. Commentary on "Six Domains of Research Ethics". Sci Eng Ethics. 2002 Apr; 8(2):215-8; discussion 219-22. PMID: 12092493.
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    37. Yücel YH, Kalichman MW, Mizisin AP, Powell HC, Weinreb RN. Histomorphometric analysis of optic nerve changes in experimental glaucoma. J Glaucoma. 1999 Feb; 8(1):38-45. PMID: 10084273.
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    38. Dines KC, Calcutt NA, Nunag KD, Mizisin AP, Kalichman MW. Effects of hindlimb temperature on sciatic nerve laser Doppler vascular conductance in control and streptozotocin-diabetic rats. J Neurol Sci. 1999 Feb 01; 163(1):17-24. PMID: 10223405.
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    39. Kalichman MW, Chalk CH, Mizisin AP. Classification of teased nerve fibers for multicenter clinical trials. J Peripher Nerv Syst. 1999; 4(3-4):233-44. PMID: 10642091.
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    40. Kalichman MW, Dines KC, Bobik M, Mizisin AP. Nerve conduction velocity, laser Doppler flow, and axonal caliber in galactose and streptozotocin diabetes. Brain Res. 1998 Nov 09; 810(1-2):130-7. PMID: 9813281.
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    41. Brown S, Kalichman MW. Effects of training in the responsible conduct of research: a survey of graduate students in experimental sciences. Sci Eng Ethics. 1998 Oct; 4(4):487-98. PMID: 11658057.
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    42. Mizisin AP, Kalichman MW, Bache M, Dines KC, DiStefano PS. NT-3 attenuates functional and structural disorders in sensory nerves of galactose-fed rats. J Neuropathol Exp Neurol. 1998 Sep; 57(9):803-13. PMID: 9737543.
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    43. Yücel YH, Gupta N, Kalichman MW, Mizisin AP, Hare W, de Souza Lima M, Zangwill L, Weinreb RN. Relationship of optic disc topography to optic nerve fiber number in glaucoma. Arch Ophthalmol. 1998 Apr; 116(4):493-7. PMID: 9565048.
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    44. Mizisin AP, Kalichman MW, Garrett RS, Dines KC. Tactile hyperesthesia, altered epidermal innervation and plantar nerve injury in the hindfeet of rats housed on wire grates. Brain Res. 1998 Mar 30; 788(1-2):13-9. PMID: 9554936.
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    45. Kalichman MW, Powell HC, Mizisin AP. Reactive, degenerative, and proliferative Schwann cell responses in experimental galactose and human diabetic neuropathy. Acta Neuropathol. 1998 Jan; 95(1):47-56. PMID: 9452821.
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    46. Dines KC, Mizisin AP, Jorge MC, Nunag KD, Kalichman MW. Effects of body and hindlimb temperature on laser Doppler blood flow and vascular conductance in rat sciatic nerve and skeletal muscle. J Neurol Sci. 1997 May 01; 148(1):7-13. PMID: 9125384.
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    47. Yee TC, Kalichman MW. Effects of aging on nerve conduction block induced by bupivacaine and procaine in rats. J Peripher Nerv Syst. 1997; 2(2):175-9. PMID: 10959231.
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    48. Brett FM, Kalichman MW, Calcutt NA, Mizisin AP. Effects of seven days of galactose feeding and aldose reductase inhibition on mast cells and vessel morphometry in rat sciatic nerve. J Neurol Sci. 1996 Sep 15; 141(1-2):6-12. PMID: 8880685.
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    49. Mizisin AP, Li L, Perello M, Freshwater JD, Kalichman MW, Roux L, Calcutt NA. Polyol pathway and osmoregulation in JS1 Schwann cells grown in hyperglycemic and hyperosmotic conditions. Am J Physiol. 1996 Jan; 270(1 Pt 2):F90-7. PMID: 8769826.
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    50. Kalichman MW, Powell HC, Calcutt NA, Mizisin AP. Mast cell degranulation and blood-nerve barrier permeability in rat sciatic nerve after 7 days of hyperglycemia. Am J Physiol. 1995 Feb; 268(2 Pt 2):H740-8. PMID: 7864200.
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    51. Kalichman MW, Sanicolas MT, Jorge MC, Roux L. Effects of cocaine on blood flow and prostaglandin metabolites in rat sciatic nerve. Am J Physiol. 1994 Jun; 266(6 Pt 2):H2515-9. PMID: 8024013.
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    52. Calcutt NA, Mizisin AP, Kalichman MW. Aldose reductase inhibition, Doppler flux and conduction in diabetic rat nerve. Eur J Pharmacol. 1994 Jan 04; 251(1):27-33. PMID: 8137868.
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    53. Kalichman MW. Physiologic mechanisms by which local anesthetics may cause injury to nerve and spinal cord. Reg Anesth. 1993 Nov-Dec; 18(6 Suppl):448-52. PMID: 8110646.
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    54. Mizisin AP, Kalichman MW. Permeability and surface area of the blood-nerve barrier in galactose intoxication. Brain Res. 1993 Jul 30; 618(1):109-14. PMID: 8402165.
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    55. Kalichman MW, Moorhouse DF, Powell HC, Myers RR. Relative neural toxicity of local anesthetics. J Neuropathol Exp Neurol. 1993 May; 52(3):234-40. PMID: 8492141.
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    56. Mizisin AP, Kalichman MW, Calcutt NA, Myers RR, Powell HC. Decreased endoneurial fluid electrolytes in normal rat sciatic nerve after aldose reductase inhibition. J Neurol Sci. 1993 May; 116(1):67-72. PMID: 8389817.
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    57. Kalichman MW, Friedman PJ. A pilot study of biomedical trainees' perceptions concerning research ethics. Acad Med. 1992 Nov; 67(11):769-75. PMID: 1418260.
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    58. Kalichman MW, Calcutt NA. Local anesthetic-induced conduction block and nerve fiber injury in streptozotocin-diabetic rats. Anesthesiology. 1992 Nov; 77(5):941-7. PMID: 1443749.
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    59. Kalichman MW, Lalonde AW. Experimental nerve ischemia and injury produced by cocaine and procaine. Brain Res. 1991 Nov 22; 565(1):34-41. PMID: 1773356.
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    60. Kalichman MW, Myers RR. Transperineurial vessel constriction in an edematous neuropathy. J Neuropathol Exp Neurol. 1991 Jul; 50(4):408-18. PMID: 2061711.
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    61. Cole DJ, Kalichman MW, Shapiro HM, Drummond JC. The nonlinear potency of sub-MAC concentrations of nitrous oxide in decreasing the anesthetic requirement of enflurane, halothane, and isoflurane in rats. Anesthesiology. 1990 Jul; 73(1):93-9. PMID: 2360745.
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    62. Mizisin AP, Kalichman MW, Myers RR, Powell HC. Role of the blood-nerve barrier in experimental nerve edema. Toxicol Pathol. 1990; 18(1 Pt 2):170-85. PMID: 2195637.
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    63. Cole DJ, Kalichman MW, Shapiro HM, Eger EI. Does 1 + 1 = 2? A continuing debate. Anesth Analg. 1990 Jan; 70(1):126-7. PMID: 2297097.
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    64. Kalichman MW, Powell HC, Myers RR. Quantitative histologic analysis of local anesthetic-induced injury to rat sciatic nerve. J Pharmacol Exp Ther. 1989 Jul; 250(1):406-13. PMID: 2746508.
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    65. Cole DJ, Kalichman MW, Shapiro HM. The nonlinear contribution of nitrous oxide at sub-MAC concentrations to enflurane MAC in rats. Anesth Analg. 1989 May; 68(5):556-62. PMID: 2719289.
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    66. Powell HC, Kalichman MW, Garrett RS, Myers RR. Selective vulnerability of unmyelinated fiber Schwann cells in nerves exposed to local anesthetics. Lab Invest. 1988 Aug; 59(2):271-80. PMID: 3404978.
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    67. Kalichman MW, Powell HC, Myers RR. Pathology of local anesthetic-induced nerve injury. Acta Neuropathol. 1988; 75(6):583-9. PMID: 3376761.
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    68. Kalichman MW, Myers RR. Behavioral and electrophysiological recovery following cryogenic nerve injury. Exp Neurol. 1987 Jun; 96(3):692-702. PMID: 3582553.
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    69. Kalichman MW, Powell HC, Reisner LS, Myers RR. The role of 2-chloroprocaine and sodium bisulfite in rat sciatic nerve edema. J Neuropathol Exp Neurol. 1986 Sep; 45(5):566-75. PMID: 3018175.
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    70. Myers RR, Kalichman MW, Reisner LS, Powell HC. Neurotoxicity of local anesthetics: altered perineurial permeability, edema, and nerve fiber injury. Anesthesiology. 1986 Jan; 64(1):29-35. PMID: 3942334.
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    71. Kalichman MW. Pharmacological investigation of convulsant gamma-aminobutyric acid (GABA) antagonists in amygdala-kindled rats. Epilepsia. 1982 Apr; 23(2):163-71. PMID: 7075571.
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