Utpal Das

Title(s)Associate Project Scientist, Neurosciences
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Serine-129 phosphorylation of α-synuclein is an activity-dependent trigger for physiologic protein-protein interactions and synaptic function. Neuron. 2023 Dec 20; 111(24):4006-4023.e10. Parra-Rivas LA, Madhivanan K, Aulston BD, Wang L, Prakashchand DD, Boyer NP, Saia-Cereda VM, Branes-Guerrero K, Pizzo DP, Bagchi P, Sundar VS, Tang Y, Das U, Scott DA, Rangamani P, Ogawa Y. PMID: 38128479; PMCID: PMC10766085.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    2. Alzheimer's disease linked Aβ42 exerts product feedback inhibition on γ-secretase impairing downstream cell signaling. bioRxiv. 2023 Oct 28. Zoltowska KM, Das U, Lismont S, Enzlein T, Maesako M, Houser MC, Franco ML, Moreira DG, Karachentsev D, Becker A, Hopf C, Vilar M, Berezovska O, Mobley W, Chávez-Gutiérrez L. PMID: 37577527; PMCID: PMC10418207.
      View in: PubMed   Mentions:
    3. Clathrin packets move in slow axonal transport and deliver functional payloads to synapses. Neuron. 2021 09 15; 109(18):2884-2901.e7. Ganguly A, Sharma R, Boyer NP, Wernert F, Phan S, Boassa D, Parra L, Das U, Caillol G, Han X, Yates JR, Ellisman MH, Leterrier C, Roy S. PMID: 34534453; PMCID: PMC8457040.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    4. Normal levels of KIF5 but reduced KLC1 levels in both Alzheimer disease and Alzheimer disease in Down syndrome: evidence suggesting defects in anterograde transport. Alzheimers Res Ther. 2021 03 10; 13(1):59. Chen XQ, Das U, Park G, Mobley WC. PMID: 33691783; PMCID: PMC7945332.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    5. Cholesterol-lowering drugs reduce APP processing to Aβ by inducing APP dimerization. Mol Biol Cell. 2021 02 01; 32(3):247-259. Langness VF, van der Kant R, Das U, Wang L, Chaves RDS, Goldstein LSB. PMID: 33296223; PMCID: PMC8098827.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    6. The cellular machinery of post-endocytic APP trafficking in Alzheimer's disease: A future target for therapeutic intervention? Prog Mol Biol Transl Sci. 2021; 177:109-122. Goldstein LSB, Das U. PMID: 33453937.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    7. Functional cooperation of α-synuclein and VAMP2 in synaptic vesicle recycling. Proc Natl Acad Sci U S A. 2019 06 04; 116(23):11113-11115. Sun J, Wang L, Bao H, Premi S, Das U, Chapman ER, Roy S. PMID: 31110017; PMCID: PMC6561242.
      View in: PubMed   Mentions: 74     Fields:    Translation:HumansCells
    8. CRISPR/Cas9 editing of APP C-terminus attenuates β-cleavage and promotes α-cleavage. Nat Commun. 2019 01 03; 10(1):53. Sun J, Carlson-Stevermer J, Das U, Shen M, Delenclos M, Snead AM, Koo SY, Wang L, Qiao D, Loi J, Petersen AJ, Stockton M, Bhattacharyya A, Jones MV, Zhao X, McLean PJ, Sproul AA, Saha K, Roy S. PMID: 30604771; PMCID: PMC6318289.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansAnimalsCells
    9. Amyloid-β Peptide Is Needed for cGMP-Induced Long-Term Potentiation and Memory. J Neurosci. 2017 07 19; 37(29):6926-6937. Palmeri A, Ricciarelli R, Gulisano W, Rivera D, Rebosio C, Calcagno E, Tropea MR, Conti S, Das U, Roy S, Pronzato MA, Arancio O, Fedele E, Puzzo D. PMID: 28626017; PMCID: PMC5518421.
      View in: PubMed   Mentions: 26     Fields:    Translation:Animals
    10. Hsc70 chaperone activity is required for the cytosolic slow axonal transport of synapsin. J Cell Biol. 2017 07 03; 216(7):2059-2074. Ganguly A, Han X, Das U, Wang L, Loi J, Sun J, Gitler D, Caillol G, Leterrier C, Yates JR, Roy S. PMID: 28559423; PMCID: PMC5496608.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    11. Visualizing APP and BACE-1 approximation in neurons yields insight into the amyloidogenic pathway. Nat Neurosci. 2016 Jan; 19(1):55-64. Das U, Wang L, Ganguly A, Saikia JM, Wagner SL, Koo EH, Roy S. PMID: 26642089; PMCID: PMC4782935.
      View in: PubMed   Mentions: 99     Fields:    Translation:AnimalsCells
    12. α-synuclein multimers cluster synaptic vesicles and attenuate recycling. Curr Biol. 2014 Oct 06; 24(19):2319-26. Wang L, Das U, Scott DA, Tang Y, McLean PJ, Roy S. PMID: 25264250; PMCID: PMC4190006.
      View in: PubMed   Mentions: 138     Fields:    Translation:HumansAnimalsCells
    13. Fast vesicle transport is required for the slow axonal transport of synapsin. J Neurosci. 2013 Sep 25; 33(39):15362-75. Tang Y, Scott D, Das U, Gitler D, Ganguly A, Roy S. PMID: 24068803; PMCID: PMC3782618.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    14. Activity-induced convergence of APP and BACE-1 in acidic microdomains via an endocytosis-dependent pathway. Neuron. 2013 Aug 07; 79(3):447-60. Das U, Scott DA, Ganguly A, Koo EH, Tang Y, Roy S. PMID: 23931995; PMCID: PMC3741682.
      View in: PubMed   Mentions: 127     Fields:    Translation:AnimalsCells
    15. The slow axonal transport of alpha-synuclein--mechanistic commonalities amongst diverse cytosolic cargoes. Cytoskeleton (Hoboken). 2012 Jul; 69(7):506-13. Tang Y, Das U, Scott DA, Roy S. PMID: 22344896; PMCID: PMC3376189.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    16. Early and selective impairments in axonal transport kinetics of synaptic cargoes induced by soluble amyloid β-protein oligomers. Traffic. 2012 May; 13(5):681-93. Tang Y, Scott DA, Das U, Edland SD, Radomski K, Koo EH, Roy S. PMID: 22309053; PMCID: PMC3593673.
      View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
    17. Mechanistic logic underlying the axonal transport of cytosolic proteins. Neuron. 2011 May 12; 70(3):441-54. Scott DA, Das U, Tang Y, Roy S. PMID: 21555071; PMCID: PMC3096075.
      View in: PubMed   Mentions: 60     Fields:    Translation:AnimalsCells
    18. Domain organization and function in GluK2 subtype kainate receptors. Proc Natl Acad Sci U S A. 2010 May 04; 107(18):8463-8. Das U, Kumar J, Mayer ML, Plested AJ. PMID: 20404149; PMCID: PMC2889583.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    19. Inhibition of protein aggregation: supramolecular assemblies of arginine hold the key. PLoS One. 2007 Nov 14; 2(11):e1176. Das U, Hariprasad G, Ethayathulla AS, Manral P, Das TK, Pasha S, Mann A, Ganguli M, Verma AK, Bhat R, Chandrayan SK, Ahmed S, Sharma S, Kaur P, Singh TP, Srinivasan A. PMID: 18000547; PMCID: PMC2064962.
      View in: PubMed   Mentions: 49     Fields:    Translation:AnimalsCells
    20. Interface peptide of Alzheimer's amyloid beta: application in purification. Biochem Biophys Res Commun. 2007 Oct 19; 362(2):538-42. Das U, Hariprasad G, Pasha S, Mann A, Ganguli M, Sharma S, Kaur P, Singh TP, Srinivasan A. PMID: 17707778.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    21. Crystal structure of a secretory signalling glycoprotein from sheep at 2.0A resolution. J Struct Biol. 2006 Dec; 156(3):505-16. Srivastava DB, Ethayathulla AS, Kumar J, Singh N, Sharma S, Das U, Srinivasan A, Singh TP. PMID: 16859926.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells