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George Sakoulas

Title(s)Associate Adjunct Professor, Pediatrics
SchoolHealth Sciences
Address9500 Gilman Drive #0687
La Jolla CA 92093
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    Collapse Research 
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    Developmental and Translational Pharmacology of Pediatric Antimicrobial Therapy
    NIH/NICHD U54HD071600Sep 26, 2011 - Jun 30, 2016
    Role: Co-Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Interleukin (IL)-1ß and IL-10 Host Responses in Patients With Staphylococcus aureus Bacteremia Determined by Antimicrobial Therapy. Clin Infect Dis. 2020 Jun 10; 70(12):2634-2640. Volk CF, Burgdorf S, Edwardson G, Nizet V, Sakoulas G, Rose WE. PMID: 31365924.
      View in: PubMed   Mentions: 1     Fields:    
    2. Genome Sequence Comparison of Staphylococcus aureus TX0117 and a Beta-Lactamase-Cured Derivative Shows Increased Cationic Peptide Resistance Accompanying Mutations in relA and mnaA. Microbiol Resour Announc. 2020 Apr 30; 9(18). Sales MJ, Sakoulas G, Szubin R, Palsson B, Arias C, Singh KV, Murray BE, Monk JM. PMID: 32354985.
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    3. Genetic Determinants Enabling Medium-Dependent Adaptation to Nafcillin in Methicillin-Resistant Staphylococcus aureus. mSystems. 2020 Mar 31; 5(2). Salazar MJ, Machado H, Dillon NA, Tsunemoto H, Szubin R, Dahesh S, Pogliano J, Sakoulas G, Palsson BO, Nizet V, Feist AM. PMID: 32234776.
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    4. Distinct Subpopulations of Intravalvular Methicillin-Resistant Staphylococcus aureus with Variable Susceptibility to Daptomycin in Tricuspid Valve Endocarditis. Antimicrob Agents Chemother. 2020 02 21; 64(3). Miller CR, Dey S, Smolenski PD, Kulkarni PS, Monk JM, Szubin R, Sakoulas G, Berti AD. PMID: 31932377.
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    5. Multicenter Cohort of Patients With Methicillin-Resistant Staphylococcus aureus Bacteremia Receiving Daptomycin Plus Ceftaroline Compared With Other MRSA Treatments. Open Forum Infect Dis. 2020 Jan; 7(1):ofz538. McCreary EK, Kullar R, Geriak M, Zasowski EJ, Rizvi K, Schulz LT, Ouellette K, Vasina L, Haddad F, Rybak MJ, Zervos MJ, Sakoulas G, Rose WE. PMID: 31938716.
      View in: PubMed   Mentions:
    6. Reduced Production of Bacterial Membrane Vesicles Predicts Mortality in ST45/USA600 Methicillin-Resistant Staphylococcus aureus Bacteremia. Antibiotics (Basel). 2019 Dec 18; 9(1). Dey S, Gudipati S, Giuliano C, Zervos MJ, Monk JM, Szubin R, Jorgensen SCJ, Sakoulas G, Berti AD. PMID: 31861446.
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    7. Cefazolin and Ertapenem Salvage Therapy Rapidly Clears Persistent Methicillin-Susceptible Staphylococcus aureus Bacteremia. Clin Infect Dis. 2019 Nov 27. Ulloa ER, Singh KV, Geriak M, Haddad F, Murray BE, Nizet V, Sakoulas G. PMID: 31773134.
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    8. Reply to Kalil et al., "Is Daptomycin plus Ceftaroline Associated with Better Clinical Outcomes than Standard of Care Monotherapy for Staphylococcus aureus Bacteremia?" Antimicrob Agents Chemother. 2019 11; 63(11). Sakoulas G, Geriak M, Haddad F, Rose W, LaPlante K, Zervos M, Kullar R, Nizet V. PMID: 31640978.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    9. Omadacycline for Acute Bacterial Skin and Skin Structure Infections. Clin Infect Dis. 2019 08 01; 69(Suppl 1):S23-S32. Abrahamian FM, Sakoulas G, Tzanis E, Manley A, Steenbergen J, Das AF, Eckburg PB, McGovern PC. PMID: 31367742.
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    10. Surprising synergy of dual translation inhibition vs. Acinetobacter baumannii and other multidrug-resistant bacterial pathogens. EBioMedicine. 2019 Aug; 46:193-201. Dillon N, Holland M, Tsunemoto H, Hancock B, Cornax I, Pogliano J, Sakoulas G, Nizet V. PMID: 31353294.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    11. Avibactam Sensitizes Carbapenem-Resistant NDM-1-Producing Klebsiella pneumoniae to Innate Immune Clearance. J Infect Dis. 2019 07 02; 220(3):484-493. Ulloa ER, Dillon N, Tsunemoto H, Pogliano J, Sakoulas G, Nizet V. PMID: 30923801.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    12. Treatment of Multidrug-Resistant Vancomycin-Resistant Enterococcus faecium Hardware-Associated Vertebral Osteomyelitis with Oritavancin plus Ampicillin. Antimicrob Agents Chemother. 2019 07; 63(7). Dahesh S, Wong B, Nizet V, Sakoulas G, Tran TT, Aitken SL. PMID: 31235559.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    13. Clinical Data on Daptomycin plus Ceftaroline versus Standard of Care Monotherapy in the Treatment of Methicillin-Resistant Staphylococcus aureus Bacteremia. Antimicrob Agents Chemother. 2019 05; 63(5). Geriak M, Haddad F, Rizvi K, Rose W, Kullar R, LaPlante K, Yu M, Vasina L, Ouellette K, Zervos M, Nizet V, Sakoulas G. PMID: 30858203.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    14. Proton-pump inhibitors do not influence clinical outcomes in patients with Staphylococcus aureus bacteremia. Therap Adv Gastroenterol. 2019; 12:1756284819834273. Caffrey AR, Timbrook TT, Ali SR, Nizet V, Sakoulas G. PMID: 30923573.
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    15. Is a Reported Penicillin Allergy Sufficient Grounds to Forgo the Multidimensional Antimicrobial Benefits of ß-Lactam Antibiotics? Clin Infect Dis. 2019 01 01; 68(1):157-164. Sakoulas G, Geriak M, Nizet V. PMID: 29986019.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    16. Characterization of genetic changes associated with daptomycin nonsusceptibility in Staphylococcus aureus. PLoS One. 2018; 13(6):e0198366. Ma Z, Lasek-Nesselquist E, Lu J, Schneider R, Shah R, Oliva G, Pata J, McDonough K, Pai MP, Rose WE, Sakoulas G, Malik M. PMID: 29879195.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    17. The Staphylococcus aureus Two-Component System AgrAC Displays Four Distinct Genomic Arrangements That Delineate Genomic Virulence Factor Signatures. Front Microbiol. 2018; 9:1082. Choudhary KS, Mih N, Monk J, Kavvas E, Yurkovich JT, Sakoulas G, Palsson BO. PMID: 29887846.
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    18. Prevention of High-Level Daptomycin-Resistance Emergence In Vitro in Streptococcus mitis-oralis by Using Combination Antimicrobial Strategies. Curr Microbiol. 2018 Aug; 75(8):1062-1067. Zapata B, Alvarez DN, Farah S, Garcia-de-la-Maria C, Miro JM, Sakoulas G, Bayer AS, Mishra NN. PMID: 29651552.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    19. Impact of cefazolin co-administration with vancomycin to reduce development of vancomycin-intermediate Staphylococcus aureus. Diagn Microbiol Infect Dis. 2018 Aug; 91(4):363-370. Singh NB, Yim J, Jahanbakhsh S, Sakoulas G, Rybak MJ. PMID: 29807674.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    20. Humanized Exposures of a ß-Lactam-ß-Lactamase Inhibitor, Tazobactam, versus Non-ß-Lactam-ß-Lactamase Inhibitor, Avibactam, with or without Colistin, against Acinetobacter baumannii in Murine Thigh and Lung Infection Models. Pharmacology. 2018; 101(5-6):255-261. Monogue ML, Sakoulas G, Nizet V, Nicolau DP. PMID: 29533955.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    21. Telavancin for refractory MRSA bacteraemia in intermittent haemodialysis recipients. J Antimicrob Chemother. 2018 03 01; 73(3):764-767. Britt NS, Tirmizi S, Ritchie DJ, Topal JE, McManus D, Nizet V, Casabar E, Sakoulas G. PMID: 29244141.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    22. Listeria monocytogenes endocarditis: case report, review of the literature, and laboratory evaluation of potential novel antibiotic synergies. Int J Antimicrob Agents. 2018 Mar; 51(3):468-478. Kumaraswamy M, Do C, Sakoulas G, Nonejuie P, Tseng GW, King H, Fierer J, Pogliano J, Nizet V. PMID: 29337066.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    23. Interaction of Antibiotics with Innate Host Defense Factors against Salmonella enterica Serotype Newport. mSphere. 2017 Nov-Dec; 2(6). Sakoulas G, Kumaraswamy M, Kousha A, Nizet V. PMID: 29242830.
      View in: PubMed   Mentions: 5     Fields:    
    24. Dissecting Out the Direct Impacts of Large-Scale Antimicrobial Stewardship Interventions on Clinical Outcomes: Can Confounding Be Overcome? Clin Infect Dis. 2017 11 13; 65(11):1956-1957. Dilworth TJ, Rose WE, Sakoulas G, Bayer AS. PMID: 29020207.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    25. Increased Endovascular Staphylococcus aureus Inoculum Is the Link Between Elevated Serum Interleukin 10 Concentrations and Mortality in Patients With Bacteremia. Clin Infect Dis. 2017 May 15; 64(10):1406-1412. Rose WE, Shukla SK, Berti AD, Hayney MS, Henriquez KM, Ranzoni A, Cooper MA, Proctor RA, Nizet V, Sakoulas G. PMID: 28205673.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    26. Evidence To Support Continuation of Statin Therapy in Patients with Staphylococcus aureus Bacteremia. Antimicrob Agents Chemother. 2017 03; 61(3). Caffrey AR, Timbrook TT, Noh E, Sakoulas G, Opal SM, Nizet V, LaPlante KL. PMID: 28069650.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    27. Classical ß-Lactamase Inhibitors Potentiate the Activity of Daptomycin against Methicillin-Resistant Staphylococcus aureus and Colistin against Acinetobacter baumannii. Antimicrob Agents Chemother. 2017 02; 61(2). Sakoulas G, Rose W, Berti A, Olson J, Munguia J, Nonejuie P, Sakoulas E, Rybak MJ, Pogliano J, Nizet V. PMID: 27872080.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    28. ß-Lactamase Inhibitors Enhance the Synergy between ß-Lactam Antibiotics and Daptomycin against Methicillin-Resistant Staphylococcus aureus. Antimicrob Agents Chemother. 2017 01; 61(1). Henson KE, Yim J, Smith JR, Sakoulas G, Rybak MJ. PMID: 27821441.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    29. Cefazolin and Ertapenem, a Synergistic Combination Used To Clear Persistent Staphylococcus aureus Bacteremia. Antimicrob Agents Chemother. 2016 11; 60(11):6609-6618. Sakoulas G, Olson J, Yim J, Singh NB, Kumaraswamy M, Quach DT, Rybak MJ, Pogliano J, Nizet V. PMID: 27572414.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    30. Fosfomycin Enhances the Activity of Daptomycin against Vancomycin-Resistant Enterococci in an In Vitro Pharmacokinetic-Pharmacodynamic Model. Antimicrob Agents Chemother. 2016 10; 60(10):5716-23. Hall Snyder AD, Werth BJ, Nonejuie P, McRoberts JP, Pogliano J, Sakoulas G, Yim J, Singh N, Rybak MJ. PMID: 27431211.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    31. Effects of vancomycin versus nafcillin in enhancing killing of methicillin-susceptible Staphylococcus aureus causing bacteremia by human cathelicidin LL-37. Eur J Clin Microbiol Infect Dis. 2016 Sep; 35(9):1441-7. Le J, Dam Q, Schweizer M, Thienphrapa W, Nizet V, Sakoulas G. PMID: 27234592.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    32. New Guidelines Endorse Old Recommendations for Invasive Enterococcal Infections. Clin Infect Dis. 2016 07 15; 63(2):281-2. Werth BJ, Smith JR, Sakoulas G. PMID: 27161781.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    33. Efficacy of ceftolozane/tazobactam versus levofloxacin in the treatment of complicated urinary tract infections (cUTIs) caused by levofloxacin-resistant pathogens: results from the ASPECT-cUTI trial. J Antimicrob Chemother. 2016 07; 71(7):2014-21. Huntington JA, Sakoulas G, Umeh O, Cloutier DJ, Steenbergen JN, Bliss C, Goldstein EJ. PMID: 26994090.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCTClinical Trials
    34. Standard susceptibility testing overlooks potent azithromycin activity and cationic peptide synergy against MDR Stenotrophomonas maltophilia. J Antimicrob Chemother. 2016 May; 71(5):1264-9. Kumaraswamy M, Lin L, Olson J, Sun CF, Nonejuie P, Corriden R, Döhrmann S, Ali SR, Amaro D, Rohde M, Pogliano J, Sakoulas G, Nizet V. PMID: 26832758.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    35. Bacterial Cytological Profiling (BCP) as a Rapid and Accurate Antimicrobial Susceptibility Testing Method for Staphylococcus aureus. EBioMedicine. 2016 Feb; 4:95-103. Quach DT, Sakoulas G, Nizet V, Pogliano J, Pogliano K. PMID: 26981574.
      View in: PubMed   Mentions: 8     Fields:    Translation:Cells
    36. When sepsis persists: a review of MRSA bacteraemia salvage therapy. J Antimicrob Chemother. 2016 Mar; 71(3):576-86. Kullar R, Sakoulas G, Deresinski S, van Hal SJ. PMID: 26565015.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    37. Penicillin Binding Protein 1 Is Important in the Compensatory Response of Staphylococcus aureus to Daptomycin-Induced Membrane Damage and Is a Potential Target for ß-Lactam-Daptomycin Synergy. Antimicrob Agents Chemother. 2016 01; 60(1):451-8. Berti AD, Theisen E, Sauer JD, Nonejuie P, Olson J, Pogliano J, Sakoulas G, Nizet V, Proctor RA, Rose WE. PMID: 26525797.
      View in: PubMed   Mentions: 12     Fields:    Translation:Cells
    38. Differential Effects of Penicillin Binding Protein Deletion on the Susceptibility of Enterococcus faecium to Cationic Peptide Antibiotics. Antimicrob Agents Chemother. 2015 Oct; 59(10):6132-9. Sakoulas G, Kumaraswamy M, Nonejuie P, Werth BJ, Rybak MJ, Pogliano J, Rice LB, Nizet V. PMID: 26195528.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    39. Azithromycin Synergizes with Cationic Antimicrobial Peptides to Exert Bactericidal and Therapeutic Activity Against Highly Multidrug-Resistant Gram-Negative Bacterial Pathogens. EBioMedicine. 2015 Jul; 2(7):690-8. Lin L, Nonejuie P, Munguia J, Hollands A, Olson J, Dam Q, Kumaraswamy M, Rivera H, Corriden R, Rohde M, Hensler ME, Burkart MD, Pogliano J, Sakoulas G, Nizet V. PMID: 26288841.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansAnimalsCells
    40. Agranulocytosis with ceftaroline high-dose monotherapy or combination therapy with clindamycin. Pharmacotherapy. 2015 Jun; 35(6):608-12. Varada NL, Sakoulas G, Lei LR, Chua J. PMID: 26037689.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    41. Clinical Outcomes of Daptomycin for Vancomycin-resistant Enterococcus Bacteremia. Clin Ther. 2015 Jul 01; 37(7):1443-1453.e2. Moise PA, Sakoulas G, McKinnell JA, Lamp KC, DePestel DD, Yoon MJ, Reyes K, Zervos MJ. PMID: 25982687.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    42. In vitro activity of daptomycin in combination with ß-lactams, gentamicin, rifampin, and tigecycline against daptomycin-nonsusceptible enterococci. Antimicrob Agents Chemother. 2015 Jul; 59(7):4279-88. Hindler JA, Wong-Beringer A, Charlton CL, Miller SA, Kelesidis T, Carvalho M, Sakoulas G, Nonejuie P, Pogliano J, Nizet V, Humphries R. PMID: 25963982.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    43. Staphylococcus aureus bacteraemia management: where do we stand and where are we going? Evid Based Med. 2015 Aug; 20(4):126. Moise PA, Sakoulas G. PMID: 25895528.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    44. Heterogeneity of genetic pathways toward daptomycin nonsusceptibility in Staphylococcus aureus determined by adjunctive antibiotics. Antimicrob Agents Chemother. 2015 May; 59(5):2799-806. Berti AD, Baines SL, Howden BP, Sakoulas G, Nizet V, Proctor RA, Rose WE. PMID: 25733508.
      View in: PubMed   Mentions: 8     Fields:    Translation:Cells
    45. ß-Lactam combinations with daptomycin provide synergy against vancomycin-resistant Enterococcus faecalis and Enterococcus faecium. J Antimicrob Chemother. 2015; 70(6):1738-43. Smith JR, Barber KE, Raut A, Aboutaleb M, Sakoulas G, Rybak MJ. PMID: 25645208.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    46. Examining the use of ceftaroline in the treatment of Streptococcus pneumoniae meningitis with reference to human cathelicidin LL-37. Antimicrob Agents Chemother. 2015 Apr; 59(4):2428-31. Sakoulas G, Nonejuie P, Kullar R, Pogliano J, Rybak MJ, Nizet V. PMID: 25605351.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    47. Comment on: Failure of combination therapy with daptomycin and synergistic ceftriaxone for enterococcal endocarditis. J Antimicrob Chemother. 2015 Apr; 70(4):1272-3. Hall Snyder A, Werth BJ, Barber KE, Sakoulas G, Rybak MJ. PMID: 25433012.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    48. Reply to Eschenauer et al. Clin Infect Dis. 2015 Feb 15; 60(4):671-2. Kullar R, McKinnell JA, Sakoulas G. PMID: 25371486.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    49. Ceftobiprole and ampicillin increase daptomycin susceptibility of daptomycin-susceptible and -resistant VRE. J Antimicrob Chemother. 2015 Feb; 70(2):489-93. Werth BJ, Barber KE, Tran KN, Nonejuie P, Sakoulas G, Pogliano J, Rybak MJ. PMID: 25304643.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    50. Heterogeneity of mprF sequences in methicillin-resistant Staphylococcus aureus clinical isolates: role in cross-resistance between daptomycin and host defense antimicrobial peptides. Antimicrob Agents Chemother. 2014 Dec; 58(12):7462-7. Bayer AS, Mishra NN, Sakoulas G, Nonejuie P, Nast CC, Pogliano J, Chen KT, Ellison SN, Yeaman MR, Yang SJ. PMID: 25288091.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    51. Daptomycin in combination with other antibiotics for the treatment of complicated methicillin-resistant Staphylococcus aureus bacteremia. Clin Ther. 2014 Oct 01; 36(10):1303-16. Dhand A, Sakoulas G. PMID: 25444563.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    52. Vancomycin plus ceftaroline shows potent in vitro synergy and was successfully utilized to clear persistent daptomycin-non-susceptible MRSA bacteraemia. J Antimicrob Chemother. 2015 Jan; 70(1):311-3. Barber KE, Rybak MJ, Sakoulas G. PMID: 25125677.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    53. Avoiding the perfect storm: the biologic and clinical case for reevaluating the 7-day expectation for methicillin-resistant Staphylococcus aureus bacteremia before switching therapy. Clin Infect Dis. 2014 Nov 15; 59(10):1455-61. Kullar R, McKinnell JA, Sakoulas G. PMID: 25048852.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    54. Antimicrobial salvage therapy for persistent staphylococcal bacteremia using daptomycin plus ceftaroline. Clin Ther. 2014 Oct 01; 36(10):1317-33. Sakoulas G, Moise PA, Casapao AM, Nonejuie P, Olson J, Okumura CY, Rybak MJ, Kullar R, Dhand A, Rose WE, Goff DA, Bressler AM, Lee Y, Pogliano J, Johns S, Kaatz GW, Ebright JR, Nizet V. PMID: 25017183.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    55. Potent synergy of ceftobiprole plus daptomycin against multiple strains of Staphylococcus aureus with various resistance phenotypes. J Antimicrob Chemother. 2014 Nov; 69(11):3006-10. Barber KE, Werth BJ, Ireland CE, Stone NE, Nonejuie P, Sakoulas G, Pogliano J, Rybak MJ. PMID: 24990867.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    56. Defining daptomycin resistance prevention exposures in vancomycin-resistant Enterococcus faecium and E. faecalis. Antimicrob Agents Chemother. 2014 Sep; 58(9):5253-61. Werth BJ, Steed ME, Ireland CE, Tran TT, Nonejuie P, Murray BE, Rose WE, Sakoulas G, Pogliano J, Arias CA, Rybak MJ. PMID: 24957825.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    57. Evaluation of the novel combination of daptomycin plus ceftriaxone against vancomycin-resistant enterococci in an in vitro pharmacokinetic/pharmacodynamic simulated endocardial vegetation model. J Antimicrob Chemother. 2014 Aug; 69(8):2148-54. Hall Snyder A, Werth BJ, Barber KE, Sakoulas G, Rybak MJ. PMID: 24777900.
      View in: PubMed   Mentions: 18     Fields:    Translation:Cells
    58. Efficacy and safety of daptomycin in patients with renal impairment: a multicenter retrospective analysis. Pharmacotherapy. 2014 Jun; 34(6):582-9. Kullar R, McClellan I, Geriak M, Sakoulas G. PMID: 24658897.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    59. Human cathelicidin LL-37 resistance and increased daptomycin MIC in methicillin-resistant Staphylococcus aureus strain USA600 (ST45) are associated with increased mortality in a hospital setting. J Clin Microbiol. 2014 Jun; 52(6):2172-4. Sakoulas G, Guram K, Reyes K, Nizet V, Zervos M. PMID: 24648548.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    60. Ceftaroline restores daptomycin activity against daptomycin-nonsusceptible vancomycin-resistant Enterococcus faecium. Antimicrob Agents Chemother. 2014; 58(3):1494-500. Sakoulas G, Rose W, Nonejuie P, Olson J, Pogliano J, Humphries R, Nizet V. PMID: 24366742.
      View in: PubMed   Mentions: 29     Fields:    Translation:Cells
    61. Nafcillin enhances innate immune-mediated killing of methicillin-resistant Staphylococcus aureus. J Mol Med (Berl). 2014 Feb; 92(2):139-49. Sakoulas G, Okumura CY, Thienphrapa W, Olson J, Nonejuie P, Dam Q, Dhand A, Pogliano J, Yeaman MR, Hensler ME, Bayer AS, Nizet V. PMID: 24297496.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansAnimalsCells
    62. Reduced glycopeptide and lipopeptide susceptibility in Staphylococcus aureus and the "seesaw effect": Taking advantage of the back door left open? Drug Resist Updat. 2013 Jul-Nov; 16(3-5):73-9. Ortwine JK, Werth BJ, Sakoulas G, Rybak MJ. PMID: 24268586.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    63. A current perspective on daptomycin for the clinical microbiologist. Clin Microbiol Rev. 2013 Oct; 26(4):759-80. Humphries RM, Pollett S, Sakoulas G. PMID: 24092854.
      View in: PubMed   Mentions: 52     Fields:    Translation:HumansCells
    64. Staphylococcal enterotoxin P predicts bacteremia in hospitalized patients colonized with methicillin-resistant Staphylococcus aureus. J Infect Dis. 2014 Feb 15; 209(4):571-7. Calderwood MS, Desjardins CA, Sakoulas G, Nicol R, Dubois A, Delaney ML, Kleinman K, Cosimi LA, Feldgarden M, Onderdonk AB, Birren BW, Platt R, Huang SS. PMID: 24041793.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    65. A multicentre evaluation of the effectiveness and safety of high-dose daptomycin for the treatment of infective endocarditis. J Antimicrob Chemother. 2013 Dec; 68(12):2921-6. Kullar R, Casapao AM, Davis SL, Levine DP, Zhao JJ, Crank CW, Segreti J, Sakoulas G, Cosgrove SE, Rybak MJ. PMID: 23928022.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    66. ß-Lactam antibiotics targeting PBP1 selectively enhance daptomycin activity against methicillin-resistant Staphylococcus aureus. Antimicrob Agents Chemother. 2013 Oct; 57(10):5005-12. Berti AD, Sakoulas G, Nizet V, Tewhey R, Rose WE. PMID: 23896478.
      View in: PubMed   Mentions: 29     Fields:    Translation:Cells
    67. Multicenter study of high-dose daptomycin for treatment of enterococcal infections. Antimicrob Agents Chemother. 2013 Sep; 57(9):4190-6. Casapao AM, Kullar R, Davis SL, Levine DP, Zhao JJ, Potoski BA, Goff DA, Crank CW, Segreti J, Sakoulas G, Cosgrove SE, Rybak MJ. PMID: 23774437.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
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    72. Microbiological profile of organisms causing bloodstream infection in critically ill patients. J Clin Med Res. 2012 Dec; 4(6):371-7. Orsini J, Mainardi C, Muzylo E, Karki N, Cohen N, Sakoulas G. PMID: 23226169.
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    75. Elevated serum interleukin-10 at time of hospital admission is predictive of mortality in patients with Staphylococcus aureus bacteremia. J Infect Dis. 2012 Nov 15; 206(10):1604-11. Rose WE, Eickhoff JC, Shukla SK, Pantrangi M, Rooijakkers S, Cosgrove SE, Nizet V, Sakoulas G. PMID: 22966128.
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    97. Susceptibility relationship between vancomycin and daptomycin in Staphylococcus aureus: facts and assumptions. Lancet Infect Dis. 2009 Oct; 9(10):617-24. Moise PA, North D, Steenbergen JN, Sakoulas G. PMID: 19778764.
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    101. Evaluating aztreonam and ceftazidime pharmacodynamics with Escherichia coli in combination with daptomycin, linezolid, or vancomycin in an in vitro pharmacodynamic model. Antimicrob Agents Chemother. 2009 Oct; 53(10):4549-55. LaPlante KL, Sakoulas G. PMID: 19620335.
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    102. Pharmacodynamics of vancomycin at simulated epithelial lining fluid concentrations against methicillin-resistant Staphylococcus aureus (MRSA): implications for dosing in MRSA pneumonia. Antimicrob Agents Chemother. 2009 Sep; 53(9):3894-901. Harigaya Y, Bulitta JB, Forrest A, Sakoulas G, Lesse AJ, Mylotte JM, Tsuji BT. PMID: 19596879.
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    105. Genotypic and phenotypic relationships among methicillin-resistant Staphylococcus aureus from three multicentre bacteraemia studies. J Antimicrob Chemother. 2009 May; 63(5):873-6. Moise PA, Smyth DS, Robinson DA, El-Fawal N, McCalla C, Sakoulas G. PMID: 19261624.
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    106. Vancomycin ototoxicity: a reevaluation in an era of increasing doses. Antimicrob Agents Chemother. 2009 Feb; 53(2):483-6. Forouzesh A, Moise PA, Sakoulas G. PMID: 19001107.
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    107. Daptomycin for soft tissue infection and neutropenia in a myelogenous leukemia patient who failed prior vancomycin therapy. Clin Adv Hematol Oncol. 2008 Nov; 6(11):813-5. Sakoulas G. PMID: 19194364.
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    108. Cryptococcal infection presenting as cellulitis in a renal transplant recipient. Transpl Infect Dis. 2009 Feb; 11(1):68-71. Orsini J, Nowakowski J, Delaney V, Sakoulas G, Wormser GP. PMID: 19000155.
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    109. Microbiological and genotypic analysis of methicillin-resistant Staphylococcus aureus bacteremia. Antimicrob Agents Chemother. 2008 Sep; 52(9):3441-3. McCalla C, Smyth DS, Robinson DA, Steenbergen J, Luperchio SA, Moise PA, Fowler VG, Sakoulas G. PMID: 18606839.
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    110. Associations between the genotypes of Staphylococcus aureus bloodstream isolates and clinical characteristics and outcomes of bacteremic patients. J Clin Microbiol. 2008 Sep; 46(9):2890-6. Lalani T, Federspiel JJ, Boucher HW, Rude TH, Bae IG, Rybak MJ, Tonthat GT, Corey GR, Stryjewski ME, Sakoulas G, Chu VH, Alder J, Steenbergen JN, Luperchio SA, Campion M, Woods CW, Fowler VG. PMID: 18596141.
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    113. Relationship of linezolid minimum inhibitory concentration and time to bacterial eradication in treatment for methicillin-resistant Staphylococcus aureus infection. Ann Pharmacother. 2008 Apr; 42(4):592-3. Moise PA, Castro RS, Sul C, Forrest A, Sakoulas G. PMID: 18349303.
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    114. Teicoplanin pharmacodynamics in reference to the accessory gene regulator (agr) in Staphylococcus aureus using an in vitro pharmacodynamic model. J Antimicrob Chemother. 2008 May; 61(5):1099-102. Rose WE, Kaatz GW, Sakoulas G, Rybak MJ. PMID: 18263568.
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    123. Daptomycin nonsusceptibility in Staphylococcus aureus with reduced vancomycin susceptibility is independent of alterations in MprF. Antimicrob Agents Chemother. 2007 Jun; 51(6):2223-5. Pillai SK, Gold HS, Sakoulas G, Wennersten C, Moellering RC, Eliopoulos GM. PMID: 17404001.
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    139. Introduction of erm(C) into a linezolid- and methicillin-resistant Staphylococcus aureus does not restore linezolid susceptibility. J Antimicrob Chemother. 2003 Apr; 51(4):1039-41. Sakoulas G, Gold HS, Venkataraman L, Moellering RC, Ferraro MJ, Eliopoulos GM. PMID: 12728937.
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    140. Staphylococcus aureus accessory gene regulator (agr) group II: is there a relationship to the development of intermediate-level glycopeptide resistance? J Infect Dis. 2003 Mar 15; 187(6):929-38. Sakoulas G, Eliopoulos GM, Moellering RC, Novick RP, Venkataraman L, Wennersten C, DeGirolami PC, Schwaber MJ, Gold HS. PMID: 12660939.
      View in: PubMed   Mentions: 75     Fields:    Translation:HumansCells
    141. Comparison of mortality associated with methicillin-resistant and methicillin-susceptible Staphylococcus aureus bacteremia: a meta-analysis. Clin Infect Dis. 2003 Jan 01; 36(1):53-9. Cosgrove SE, Sakoulas G, Perencevich EN, Schwaber MJ, Karchmer AW, Carmeli Y. PMID: 12491202.
      View in: PubMed   Mentions: 390     Fields:    Translation:HumansCells
    142. Linezolid resistance in Staphylococcus aureus: characterization and stability of resistant phenotype. J Infect Dis. 2002 Dec 01; 186(11):1603-7. Pillai SK, Sakoulas G, Wennersten C, Eliopoulos GM, Moellering RC, Ferraro MJ, Gold HS. PMID: 12447736.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansCells
    143. Prevalence of the fsr locus in Enterococcus faecalis infections. J Clin Microbiol. 2002 Jul; 40(7):2651-2. Pillai SK, Sakoulas G, Gold HS, Wennersten C, Eliopoulos GM, Moellering RC, Inouye RT. PMID: 12089299.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    144. Accessory gene regulator (agr) locus in geographically diverse Staphylococcus aureus isolates with reduced susceptibility to vancomycin. Antimicrob Agents Chemother. 2002 May; 46(5):1492-502. Sakoulas G, Eliopoulos GM, Moellering RC, Wennersten C, Venkataraman L, Novick RP, Gold HS. PMID: 11959587.
      View in: PubMed   Mentions: 145     Fields:    Translation:HumansCells
    145. Methicillin-resistant Staphylococcus aureus: comparison of susceptibility testing methods and analysis of mecA-positive susceptible strains. J Clin Microbiol. 2001 Nov; 39(11):3946-51. Sakoulas G, Gold HS, Venkataraman L, DeGirolami PC, Eliopoulos GM, Qian Q. PMID: 11682512.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansCells
    146. BK-related polyomavirus vasculopathy in a renal-transplant recipient. N Engl J Med. 2001 Oct 25; 345(17):1250-5. Petrogiannis-Haliotis T, Sakoulas G, Kirby J, Koralnik IJ, Dvorak AM, Monahan-Earley R, DE Girolami PC, DE Girolami U, Upton M, Major EO, Pfister LA, Joseph JT. PMID: 11680445.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    147. Linezolid resistance in a clinical isolate of Staphylococcus aureus. Lancet. 2001 Jul 21; 358(9277):207-8. Tsiodras S, Gold HS, Sakoulas G, Eliopoulos GM, Wennersten C, Venkataraman L, Moellering RC, Ferraro MJ. PMID: 11476839.
      View in: PubMed   Mentions: 178     Fields:    Translation:HumansCells
    148. Methicillin-susceptible Staphylococcus aureus: believe it, or not. Arch Intern Med. 2001 May 14; 161(9):1237-8. Sakoulas G, Degirolami PC, Gold HS. PMID: 11343454.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    149. Brainstem and striatal encephalitis complicating Mycoplasma pneumoniae pneumonia: possible benefit of intravenous immunoglobulin. Pediatr Infect Dis J. 2001 May; 20(5):543-5. Sakoulas G. PMID: 11368117.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    150. Corynebacterium jeikeium native valve endocarditis following femoral access for coronary angiography. Clin Infect Dis. 2001 Apr 01; 32(7):E120-1. Ross MJ, Sakoulas G, Manning WJ, Cohn WE, Lisbon A. PMID: 11264050.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    151. Successful use of cyclosporine in the treatment of glucocorticoid- resistant nongranulomatous chronic idiopathic enterocolitis. Gastroenterology. 1999 Nov; 117(5):1259-60. Sakoulas G, Anastopoulos H. PMID: 10610339.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    152. Hypercalcemia in an AIDS patient treated with growth hormone. AIDS. 1997 Sep; 11(11):1353-6. Sakoulas G, Tritos NA, Lally M, Wanke C, Hartzband P. PMID: 9302445.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    153. [Role of endogenous basic fibroblast growth factor in experimental duodenal ulcer]. Orv Hetil. 1995 Jul 09; 136(28):1501-3. Sándor Z, Kusstatscher S, Sakoulas G, Szabó S. PMID: 7637967.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    154. Molecular and cellular basis of ulcer healing. Scand J Gastroenterol Suppl. 1995; 208:3-8. Szabo S, Kusstatscher S, Sandor Z, Sakoulas G. PMID: 7777801.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    155. Growth factors: new 'endogenous drugs' for ulcer healing. Scand J Gastroenterol Suppl. 1995; 210:15-8. Szabo S, Kusstatscher S, Sakoulas G, Sandor Z, Vincze A, Jadus M. PMID: 8578198.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    156. Genomic sequences capable of committing mouse and rat fibroblasts to adipogenesis. Nucleic Acids Res. 1993 May 11; 21(9):2223-8. Colón-Teicher L, Wise LS, Martino JJ, Baskin L, Sakoulas G, Pollack RE, Chen S. PMID: 8502564.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    157. Excess wild-type p53 blocks initiation and maintenance of simian virus 40 transformation. Mol Cell Biol. 1991 Jul; 11(7):3472-83. Fukasawa K, Sakoulas G, Pollack RE, Chen S. PMID: 1646391.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
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